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1137

Inhibitors & Agonists

5

Screening Libraries

56

Fluorescent Dye

45

Biochemical Assay Reagents

67

Peptides

23

MCE Kits

1

Inhibitory Antibodies

200

Natural
Products

45

Isotope-Labeled Compounds

5

Click Chemistry

9

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-D1436
    PBFI

    		Fluorescent Dye Neurological Disease
    PBFI is the fluorescent indicator that is widely used for the determination of intracellular concentrations of K + .
    PBFI
  • HY-77537
    7-Deazaxanthine

    7DX

    		 Thymidylate Synthase Cardiovascular Disease
    7-Deazaxanthine (7DX) is an inhibitor of thymidine phosphorylase (TPase). 7-Deazaxanthine inhibits TPase reaction in a concentration-dependent manner with an IC50 value of 40 μM. 7-Deazaxanthine also has a significant angiogenesis inhibitory effect .
    7-Deazaxanthine
  • HY-D0221
    2,4,6-Tri-2-pyridinyl-1,3,5-triazine

    NSC 112125; 2,4,6-Tipyidyl-s-tiazie

    		 Fluorescent Dye Others
    2,4,6-Tri-2-pyridinyl-1,3,5-triazine (NSC 112125) is a commonly used fluorescent dye for detecting iron. 2,4,6-Tri-2-pyridinyl-1,3,5-triazine forms a complex with Fe (II) and can be quantified as a measure of iron concentration by colorimetric detection at 594 nm .
    2,4,6-Tri-2-pyridinyl-1,3,5-triazine
  • HY-B2150
    4-Hydroxyantipyrine

    4-Hydroxyphenazone; NSC 174055

    		 Drug Metabolite Others
    4-Hydroxyantipyrine (4-Hydroxyphenazone; NSC 174055) is the major metabolite of Antipyrine (HY-B0171), can be as a biodistribution promoter. 4-Hydroxyantipyrine can increase distribution of concentration ratio of Citicoline and Antipyrine in the brain .
    4-Hydroxyantipyrine
  • HY-109500
    Masoprocol

    meso-Nordihydroguaiaretic acid; meso-NDGA

    		 Lipoxygenase Metabolic Disease Cancer
    Masoprocol (meso-Nordihydroguaiaretic acid) is a potent and orally active lipoxygenase inhibitor. Masoprocol shows antihyperglycemic activity. Masoprocol decreases the glucose concentration and hepatic triglyceride in vivo. Masoprocol has the potential for the research of type II diabetes .
    Masoprocol
  • HY-157646
    MZ-101

    GYS1-IN-2

    		 Others Metabolic Disease
    MZ-101 (GYS1-IN-2) is an orally active, potent and selective small-molecule glycogen synthase 1 (GYS1) inhibitor with with an IC50 value of 0.041 µM. MZ-101 reduces glycogen concentrations in cells and in mice. MZ-101 can used to study GYS1 -mediated Pompe disease and other glycogen storage diseases .
    MZ-101
  • HY-N10349
    Gluconasturtiin

    		Others Infection
    Gluconasturtiin is a feeding activator for the larvae of P. maculipennis. High concentrations of gluconasturtiin is toxic to the larvae .
    Gluconasturtiin
  • HY-137325
    2-Chloro-ATP

    		Guanylate Cyclase Others
    2-Chloro-ATP is a soluble guanylate cyclase inhibitor that increases intracellular calcium concentration at low concentrations through a mechanism independent of inositol phosphate production .
    2-Chloro-ATP
  • HY-B2150S
    4-Hydroxyantipyrine-d3

    4-Hydroxyphenazone-d3; NSC 174055-d3

    		 Drug Metabolite Isotope-Labeled Compounds Others
    4-Hydroxyantipyrine-d3 is the deuterium labeled 4-Hydroxyantipyrine. 4-Hydroxyantipyrine is the major metabolite of Antipyrine, can be as a biodistribution promoter. 4-Hydroxyantipyrine can increase distribution of concentration ratio of Antipyrine in the brain[1][2][3].
    4-Hydroxyantipyrine-d3
  • HY-W286073
    Hexaethylene glycol decyl ether

    		Biochemical Assay Reagents Others
    Hexaethylene glycol decyl ether is a non-ionic surfactant, which forms micelle, and can be utilized in the cosmetics, pharmaceuticals and food industries .
    Hexaethylene glycol decyl ether
  • HY-163203
    DDC18-8A

    		Bacterial Infection
    DDC18-8A is an amphiphilic dendrimer that exhibits high antibacterial and antibiofilm efficacy .
    DDC18-8A
  • HY-P10562
    BMV Gag-(7−25)

    		TMV Others
    BMV Gag-(7?25) is an arginine-rich peptide with cell-penetrating ability. BMV Gag-(7?25) can be used in drug delivery and gene therapy research .
    BMV Gag-(7−25)
  • HY-119401
    CAY10444
    1 Publications Verification

    BML-241

    		 LPL Receptor Cancer
    CAY10444 (BML-241) is a sphingosine-1-phosphate 3 (S1P3) antagonist. CAY10444 inhibits by 37% S1P-induced increases in Ca2+ in HeLa cells expressing S1P3 receptors .
    CAY10444
  • HY-U00027
    Quinotolast sodium

    FR71021

    		 Histamine Receptor Leukotriene Receptor Prostaglandin Receptor Inflammation/Immunology Endocrinology
    Quinotolast sodium in the concentration range of 1-100 μg/mL inhibits histamine, LTC4 and PGD2 release in a concentration-dependent manner.
    Quinotolast sodium
  • HY-P5366
    PEP1

    		Liposome Others
    PEP1 is a biological active peptide. (PEP1 binds to POPC SLBs at Low Concentration, High Concentration of PEP1 Leads to POPC SLBs Lysis)
    PEP1
  • HY-117445
    Oxazole yellow

    		Fluorescent Dye Others
    Oxazole yellow is a cyanine dye composed of benzoxazole and quinoline rings connected by a linker. It is almost non-luminescent in water, but its green fluorescence is significantly enhanced after intercalation in double-stranded DNA. Oxazole yellow can be used to detect cell apoptosis .
    Oxazole yellow
  • HY-119092
    Bisaramil

    		Sodium Channel Cardiovascular Disease
    Bisaramil is an orally active antiarrhythmic agent. Bisaramil exerts concentration dependent inhibitory effect on PMA-stimulated free radical generation and prolonged the time lag concentration dependently .
    Bisaramil
  • HY-B1065R
    Aceglutamide (Standard)

    α-N-Acetyl-L-glutamine (Standard); N2-Acetylglutamine (Standard)

    		 Autophagy Endogenous Metabolite Neurological Disease
    Aceglutamide (Standard) is the analytical standard of Aceglutamide. This product is intended for research and analytical applications. Aceglutamide (α-N-Acetyl-L-glutamine) is a psychostimulant and nootropic, used to improve memory and concentration[1].
    Aceglutamide (Standard)
  • HY-W800693
    BP Fluor 405 picolyl azide

    		Fluorescent Dye Others
    BP Fluor 405 Picolyl Azide is an advanced fluorescent probe that incorporatess a copper-chelating motif to raise the effective concentration of Cu(I) at the reaction site. The rate of the CuAAC reaction depends on the concentrations of all reagents, including copper, therefore raising the effective copper concentration at the reaction site dramatically increases the rate of CuAAC reaction without increasing the concentrations of azide reagent or copper. In addition, the use of picolyl azide instead of conventional azides allows for at least a tenfold reduction in the concentration of the copper catalyst without sacrificing the efficiency of labeling. In summary, the introduction of a picolyl moiety into an azide probe leads to a substantial increase in the sensitivity of alkyne detection. This is of special value for the detection of low abundance targets or where significant increase in signal intensity is desired.
    BP Fluor 405 picolyl azide
  • HY-W800697
    BP Fluor 430 picolyl azide

    		Fluorescent Dye Others
    BP Fluor 430 Picolyl Azide is an advanced fluorescent probe that incorporatess a copper-chelating motif to raise the effective concentration of Cu(I) at the reaction site. The rate of the CuAAC reaction depends on the concentrations of all reagents, including copper, therefore raising the effective copper concentration at the reaction site will dramatically increase the rate of CuAAC reaction without the need to increase concentration of azide reagent or copper. In addition, the use of BP Fluor 430 Picolyl Azide instead of conventional BP Fluor 430 Azide allows for at least a tenfold reduction in the concentration of the copper catalyst without sacrificing the efficiency of labeling. In summary, the introduction of a picolyl moiety into an azide probe leads to a substantial increase in the sensitivity of alkyne detection. This is of special value for the detection of low abundance targets or where significant increase in signal intensity is desired.
    BP Fluor 430 picolyl azide
  • HY-P2206
    Zelkovamycin

    		Bacterial Infection
    Zelkovamycin is a cyclic peptide antibiotic originally isolated from Streptomyces. It inhibits growth of X. oryzae, P. oryzae, S. aureus, and A. laidlawii in a concentration-dependent manner when used at concentrations ranging from 0.01 to 300 μg/mL.
    Zelkovamycin
  • HY-122622
    PF-04471141 hydrochloride

    		Phosphodiesterase (PDE) Others
    PF-04471141 (hydrochloride) is a compound that regulates intracellular cAMP and cGMP concentrations. It is a PDE1 inhibitor and has different effects on different PDE enzymes in regulating intracellular signaling molecule concentrations and cell proliferation in vascular smooth muscle cells.
    PF-04471141 hydrochloride
  • HY-113286
    4-Guanidinobutanoic acid

    		Endogenous Metabolite Others
    4-Guanidinobutanoic acid is a normal metabolite present in low concentrations.
    4-Guanidinobutanoic acid
  • HY-100921
    Spaglumic Acid

    N-Acetylaspartylglutamic acid

    		 Endogenous Metabolite Neurological Disease
    Spaglumic Acid (N-Acetylaspartylglutamic acid) is a neuropeptide found in millimolar concentrations in brain.
    Spaglumic Acid
  • HY-136408
    Malonyl CoA lithium

    Malonyl coenzyme A lithium

    		 Mitochondrial Metabolism Metabolic Disease
    Malonyl CoA (Malonyl Coenzyme A) lithium is an inhibitor of carnitine palmitoyl transferase 1 (CPT1). High Malonyl CoA lithium concentrations suppress fatty acid oxidation, while low Malonyl CoA lithium concentrations are permissive for fat oxidation .
    Malonyl CoA lithium
  • HY-148075
    PI4KIIIbeta-IN-11

    		PI4K Infection
    PI4KIIIbeta-IN-11 is an inhibitor of PI4KIIIβ, with a mean pIC50 value of at least 9.1. PI4KIIIβ plays a key role in diseases research of RNA viruses and Plasmodium falciparum .
    PI4KIIIbeta-IN-11
  • HY-13655A
    Isatoribine

    		Toll-like Receptor (TLR) Infection
    Isatoribine is a TLR7 agonist. Isatoribine is used in the study of chronic hepatitis C virus (HCV) infection .
    Isatoribine
  • HY-44076
    LAP
    1 Publications Verification

    Lithium phenyl-2,4,6-trimethylbenzoylphosphinate

    		 Biochemical Assay Reagents Others Cancer
    LAP (Lithium phenyl-2,4,6-trimethylbenzoylphosphinate) is a free radical initiator. The free radicals produced by LAP under bioprinting conditions are potentially cytotoxic and mutagenic. In addition, the concentration of LAP affects the mechanical strength of 3D printed scaffolds. Generally, the concentration range of LAP used for curing is 0.05%-1%. The elastic modulus produced at a concentration of 0.1% is the highest, with enhanced mechanical properties and excellent biocompatibility .
    LAP
  • HY-N13182
    Taxoquinone

    		Others Others
    Taxoquinone is an antioxidant derived from Metasequoia glyptostroboides and belongs to the diterpenoid class of compounds. At a concentration of 150 μg/mL, Taxoquinone exhibits a maximum inhibition of DPPH radicals of 81.29%, demonstrating superior antioxidant activity compared to Ascorbic acid and α-tocopherol at the same concentration .
    Taxoquinone
  • HY-W013275
    MCLA hydrochloride
    1 Publications Verification

    		 Reactive Oxygen Species Others
    MCLA hydrochloride is a chemiluminescent reagent which can be used to quantify aqueous concentrations of superoxide.
    MCLA hydrochloride
  • HY-137392
    Cathepsin L-IN-4

    1-Naphthalenesulfonyl-Ile-Trp-CHO

    		 Cathepsin Others
    Cathepsin L-IN-4 is an inhibitor of cathepsin L with IC50 at nanomolar concentrations .
    Cathepsin L-IN-4
  • HY-B0398
    Nalidixic acid
    2 Publications Verification

    		 Bacterial Antibiotic Topoisomerase Infection
    Nalidixic acid, a quinolone antibiotic, is effective against both gram-positive and gram-negative bacteria. Nalidixic acid acts in a bacteriostatic manner in lower concentrations and is bactericidal in higher concentrations. Nalidixic acid inhibits a subunit of DNA gyrase and topoisomerase IV and reversibly blocks DNA replication in susceptible bacteria .
    Nalidixic acid
  • HY-B0398A
    Nalidixic acid sodium salt
    2 Publications Verification

    		 Bacterial Antibiotic Topoisomerase Infection
    Nalidixic acid sodium salt, a quinolone antibiotic, is effective against both gram-positive and gram-negative bacteria. Nalidixic acid acts in a bacteriostatic manner in lower concentrations and is bactericidal in higher concentrations. Nalidixic acid inhibits a subunit of DNA gyrase and topoisomerase IV and reversibly blocks DNA replication in susceptible bacteria .
    Nalidixic acid sodium salt
  • HY-Y0313S2
    p-Hydroxybenzaldehyde-d5

    		GABA Receptor Endogenous Metabolite Neurological Disease
    p-Hydroxybenzaldehyde-d5 is the deuterium labeled p-Hydroxybenzaldehyde[1]. p-Hydroxybenzaldehyde is a one of the major components in vanilla aroma, with antagonistic effect on GABAA receptor of the α1β2γ2S subtype at high concentrations[2].
    p-Hydroxybenzaldehyde-d5
  • HY-P10713
    PTZ-GFFY

    		Biochemical Assay Reagents Others
    PTZ-GFFY is a super-gelator that can form a hydrogel at the ultra-low concentration .
    PTZ-GFFY
  • HY-P1528
    Autocamtide 2, amide

    		CaMK Autophagy Neurological Disease
    Autocamtide 2, amide is a substrate (100 μM final concentration) for CaMK family assays.
    Autocamtide 2, amide
  • HY-D1639
    5,5'-Dibromo BAPTA tetrapotassium

    		Fluorescent Dye Others
    5,5'-Dibromo BAPTA tetrapotassium is a calcium chelator, can be formulated into a buffer with a defined calcium ion concentration. 5,5'-Dibromo BAPTA tetrapotassium can control the concentration of calcium ions inside and outside the cell and can be used in studies of calcium physiological activity .
    5,5'-Dibromo BAPTA tetrapotassium
  • HY-N13073
    6-Gingediol

    		Others Others
    6-Gingediol (compound 13) is a pungent component of ginger with potential anti-serotonin and gastric mucosal protective effects. 6-Gingediol has no pungent effect at concentrations below 10 μM, but the pungent effect is significant at concentrations above 100 μM or even 1000 μM .
    6-Gingediol
  • HY-170327
    ZCL279

    		Ras Cancer
    ZCL279 is a small molecule modulator (SMM) that inhibits Cdc42-intersectin (ITSN) interaction. ZCL279 can activate Cdc42 (a cytoplasmic small GTPase in the Ras superfamily) at lower concentrations (<10 μM) and significantly inhibit it at higher concentrations (<10 μM) .
    ZCL279
  • HY-B2179
    Cloperastine fendizoate

    		Potassium Channel Inflammation/Immunology
    Cloperastine fendizoate inhibits the hERG K + currents in a concentration-dependent manner with an IC50 value of 27 nM.
    Cloperastine fendizoate
  • HY-B2133
    Cloperastine hydrochloride

    		Potassium Channel Inflammation/Immunology
    Cloperastine hydrochloride inhibits the hERG K + currents in a concentration-dependent manner with an IC50 value of 27 nM .
    Cloperastine hydrochloride
  • HY-113486
    Lathosterol
    2 Publications Verification

    		 Endogenous Metabolite Metabolic Disease
    Lathosterol is a cholesterol-like molecule. Serum Lathosterol concentration is an indicator of whole-body cholesterol synthesis.
    Lathosterol
  • HY-146296
    Xanthine oxidoreductase-IN-1

    		Xanthine Oxidase Metabolic Disease
    The compound is a xanthine oxidoreductase (XOR) inhibitor with high inhibitory concentration, and the value of ic50 is 7.0 nm.
    Xanthine oxidoreductase-IN-1
  • HY-15915
    DTNB
    5+ Cited Publications

    Ellman’s Reagent

    		 Biochemical Assay Reagents Others
    DTNB (Ellman’s Reagent) is a chemical used to quantify the number or concentration of thiol groups .
    DTNB
  • HY-129811
    Bis-ANS dipotassium

    		Microtubule/Tubulin Neurological Disease
    Bis-ANS dipotassium is a fluorescent probe of hydrophobic protein. Bis-ANS binds to tubulin with a Kd of 2 μM . Bis-ANS dipotassium is a potent biphasic modulator of protein liquid-liquid phase separation (LLPS). Bis-ANS dipotassium promotes LLPS at low concentrations but suppresses LLPS at high concentrations .
    Bis-ANS dipotassium
  • HY-172151
    PPO-IN-17

    		Herbicide Protoporphyrinogen IX oxidase Others
    PPO-IN-17 (Compound 6R) is the inhibitor protoporphyrinogen IX oxidase (PPO) that inhibits Nicotiana tobacco PPO (NtPPO) with Ki of 30.34 nM. PPO-IN-17 exhibits herbicidal activity that inhibits barnyardgrass (E. crus-galli), foxtail grass (D. sanguinalis), alfalfa (M. sativa) and Canada cocklebur (C. canadensis) (>95% inhibition rate at a concentration of 37.5 g/hm 2). PPO-IN-17 exhibits no toxicity on rice (at a concentration of 75 g/hm 2) or on honeybees (at a concentration of 6400 mg/kg) .
    PPO-IN-17
  • HY-17461S1
    Cortisone-d8

    		Isotope-Labeled Compounds Glucocorticoid Receptor Endogenous Metabolite Inflammation/Immunology Endocrinology
    Cortisone-d8 is the deuterium labeled Cortisone. Cortisone (17-Hydroxy-11-dehydrocorticosterone), an oxidized metabolite of Cortisol (a Glucocorticoid). Cortisone acts as an immunosuppressant and anti-inflammatory agent. Cortisone can partially intervene in binding of Glucocorticoid to Glucocorticoid-receptor at high concentrations[1][3][4].
    Cortisone-d8
  • HY-W099540
    OES2-0017

    		Bacterial Infection
    OES2-0017 shows potent synergy with polyamines and growth-inhibitory effects at the low micromolar range. OES2-0017 inhibits spermine/spermidine acetyltransferase (SpeG) (IC50: 34.82 μM ) and other polyamine detoxification enzymes in low concentrations, perturbed the bacterial membrane in higher concentrations .
    OES2-0017
  • HY-P5981
    Chromozym t-PA

    		Biochemical Assay Reagents Others
    Chromozym t-PA can be used for determination of t-PA (tissue plasminogen activator) concentration
    Chromozym t-PA
  • HY-B1065
    Aceglutamide

    α-N-Acetyl-L-glutamine; N2-Acetylglutamine

    		 Autophagy Endogenous Metabolite Neurological Disease
    Aceglutamide (α-N-Acetyl-L-glutamine) is a psychostimulant and nootropic, used to improve memory and concentration .
    Aceglutamide

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