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ATP competetive

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-D0183
    ATP-polyamine-biotin
    1 Publications Verification

    		 Biochemical Assay Reagents Others
    ATP-polyamine-biotin, the first cell-permeable ATP analogue, is an efficient kinase cosubstrate. ATP-polyamine-biotin promotes biotin labeling of kinase substrates in live cells .
    ATP-polyamine-biotin
  • HY-155754
    3′-Acetate-ATP

    		ATP Synthase Others
    3’-Acetate-ATP, an ATP analogue, is ATP acetylation product with an maxima uv absorption at 259 nm in water at neutral pH. 3’-Acetate-ATP exerts a blocking effect on nucleic acid polymerization .
    3′-Acetate-ATP
  • HY-134262
    8-Bromo-ATP

    8-Bromoadenosine 5'-triphosphate; 8-Br-ATP

    		 P2X Receptor Cancer
    8-Bromo-ATP (8-Bromoadenosine 5'-triphosphate), an ATP analogue, is a purinergic P2X receptor agonist. 8-Bromo-ATP shows cytotoxic to multiple myeloma cells with an IC50 of 23.1 μM .
    8-Bromo-ATP
  • HY-157046
    ATP Synthesis-IN-2

    		Bacterial ATP Synthase Infection
    ATP Synthesis-IN-2 (Compound 5) is an antibacterial compound. ATP Synthesis-IN-2 is a potent ATP synthesis activity inhibitor with IC50 against Pseudomonas aeruginosa (PA) Value of 0.7 μg/mL .
    ATP Synthesis-IN-2
  • HY-149736
    ATP Synthesis-IN-3

    		PKA ATP Synthase Cardiovascular Disease
    ATP Synthesis-IN-3 (compound 31) is an ATP hydrolysis inhibitor with protective effects during myocardial ischemia. ATP Synthesis-IN-3 can increase the ATP content of ischemic cardiomyocytes, increase the phosphorylation of PKA and phospholamban, and inhibit ischemia-induced apoptosis .
    ATP Synthesis-IN-3
  • HY-131760
    2'-NH2-ATP

    2'-Amino-2'-deoxyadenosine-5'-triphosphate, 2′-Amino-2′-deoxy-ATP

    		 Biochemical Assay Reagents Metabolic Disease
    2'-NH2-ATP (2'-Amino-2'-deoxyadenosine-5'-triphosphate), an adenosine derivative, is a weak competitive inhibitor of ATP, with a Ki of 2.3 mM. 2'-NH2-ATP can be used in nucleic acid labeling .
    2'-NH2-ATP
  • HY-134361
    ATP-γ-S tetrasodium

    		P2Y Receptor Eukaryotic Initiation Factor (eIF) Neurological Disease Metabolic Disease Inflammation/Immunology
    ATP-γ-S (tetrasodium) is a P2Y11 receptor agonist, an antioxidant and a neuroprotective agent. ATP-γ-S (tetrasodium) can be used as a substrate for the nucleotide hydrolysis and RNA unwinding activities of eukaryotic translation initiation factor eIF4A. ATP-γ-S (tetrasodium) is active in ATP hydrolysis .
    ATP-γ-S tetrasodium
  • HY-134290
    8-Chloro-ATP

    		Topoisomerase Cancer
    8-Chloro-ATP, an ATP (HY-B2176) analog, is a topoisomerase II (Topo II) inhibitor. 8-Chloro-ATP inhibits DNA synthesis and induces DNA double-stranded breaks (DSBs). 8-Chloro-ATP inhibits Topo II-catalyzed ATP hydrolysis .
    8-Chloro-ATP
  • HY-162804
    ATP synthase inhibitor 3

    		Bacterial ATP Synthase Infection
    ATP synthase inhibitor 3 (compound PT6) is an orally active inhibitor of mycobacterial F-ATP synthase (IC50=0.788 μM). ATP synthase inhibitor 3 inhibits the growth of Mycobacterium tuberculosis H37Rv strain (ATCC-27294) in vitro and depletes intracellular ATP levels at an IC50 value of 30μM .
    ATP synthase inhibitor 3
  • HY-157045
    ATP Synthesis-IN-1

    		ATP Synthase Infection
    ATP Synthesis-IN-1 (Compound 4), quinoline derivative, is a potent inhibitor of PA ATP synthesis activity. ATP Synthesis-IN-1 has PA ATP synthesis inhibition with IC50 value of 11.1μg/mL. ATP Synthesis-IN-1 also has antibacterial activity. ATP Synthesis-IN-1 can be used for the research of drug-resistant PA infection .
    ATP Synthesis-IN-1
  • HY-134398
    Kinetin triphosphate

    6-Fu-ATP; KTP

    		 PINK1/Parkin Neurological Disease Cancer
    Kinetin triphosphate(6-Fu-ATP; KTP) is an ATP analogue that regulates or enhances kinase function with higher catalytic efficiency than its endogenous substrate, ATP. Kinetin triphosphate can be used in Parkinson's disease research .
    Kinetin triphosphate
  • HY-131800
    3'-Deoxy-3'-amino-ATP

    		ATP Synthase Metabolic Disease
    3'-Deoxy-3'-amino-ATP, an ATP analogue, is a potent and competitive inhibitor of ATP, with a Ki of 2.3 μM. 3'-Deoxy-3'-amino-ATP can be used to synthesis of 3′-Amino-3′-deoxy transfer RNA by incorporation into the 3' terminus of tRNA-C-C .
    3'-Deoxy-3'-amino-ATP
  • HY-136647
    8-Bromoadenosine 5'-triphosphate tetrasodium

    8-Br-ATP tetrasodium

    		 Drug Derivative Others
    8-Bromoadenosine 5'-triphosphate tetrasodium (8-Br-ATP tetrasodium) is an ATP analogue. ATP is a central component of energy storage and metabolism in vivo .
    8-Bromoadenosine 5'-triphosphate tetrasodium
  • HY-134320B
    8-Azido-ATP trisodium

    8-Azidoadenosine 5'-triphosphate trisodium; 8-N3-ATP trisodium

    		 Potassium Channel Metabolic Disease
    8-Azido-ATP (8-N3-ATP) trisodium, a photoreactable nucleotide analog, is useful for the identification of proteins, such as DNA-dependent RNA polymerase. 8-Azido-ATP trisodium is a click chemistry reagent that contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. 8-Azido-ATP trisodium can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups .
    8-Azido-ATP trisodium
  • HY-134290A
    8-Chloro-ATP tetrasodium

    		Topoisomerase Cancer
    8-Chloro-ATP tetrasodium, an ATP (HY-B2176) analog, is a topoisomerase II (Topo II) inhibitor. 8-Chloro-ATP tetrasodium inhibits DNA synthesis and induces DNA double-stranded breaks (DSBs). 8-Chloro-ATP tetrasodium inhibits Topo II-catalyzed ATP hydrolysis .
    8-Chloro-ATP tetrasodium
  • HY-146388
    Mtb ATP synthase-IN-1

    		Bacterial ATP Synthase Infection
    Mtb ATP synthase-IN-1 (compound 6ab) is a potent Mycobacterium tuberculosis (Mtb) ATP synthase inhibitor, with MIC of 0.452-0.499 μg/mL against Mtb. Mtb ATP synthase-IN-1 has good metabolic stability, low cytotoxicity (Vero IC50 > 64 μg/mL), and acceptable oral bioavailability. Mtb ATP synthase-IN-1 can be used for researching anti-mycobacterium .
    Mtb ATP synthase-IN-1
  • HY-134398A
    Kinetin triphosphate tetrasodium

    6-Fu-ATP tetrasodium; KTP tetrasodium

    		 PINK1/Parkin Neurological Disease Cancer
    Kinetin triphosphate(6-Fu-ATP) tetrasodium is an ATP analogue that regulates or enhances kinase function with higher catalytic efficiency than its endogenous substrate, ATP. Kinetin triphosphate tetrasodium can be used in Parkinson's disease research .
    Kinetin triphosphate tetrasodium
  • HY-134320
    8-Azido-ATP

    8-Azidoadenosine 5'-triphosphate; 8-N3-ATP

    		 Potassium Channel Metabolic Disease
    8-Azido-ATP, a photoreactable nucleotide analog, is useful for the identification of proteins, such as DNA-dependent RNA polymerase . 8-Azido-ATP is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    8-Azido-ATP
  • HY-134031
    Ara-ATP

    		DNA/RNA Synthesis Others
    Ara-ATP, a structural analog of ATP, inhibits poly(A) polymerase activity by competing with ATP .
    Ara-ATP
  • HY-U00451
    ATP-Red 1
    4 Publications Verification

    		 Fluorescent Dye Others
    ATP-Red 1 is a multisite-binding switchable fluorescent probe, and can selectively and rapidly responds to intracellular concentrations of ATP in living cells.
    ATP-Red 1
  • HY-137418
    2-MeS-ATP

    2-Methylthio-ATP

    		 P2Y Receptor Others Inflammation/Immunology
    2-MeS-ATP (2-Methylthio-ATP) is an analog of adenosine nucleotides and acts as a P2Y purinergic receptor agonist specific for adenosine nucleotide activation. 2-MeS-ATP is also able to inhibit the release of toxic mediators from macrophages stimulated by endotoxin (LPS). 2-MeS-ATP can be used in the study of endotoxin shock and inflammatory diseases .
    2-MeS-ATP
  • HY-134393
    6-Me-ATP

    N6-Methyl-ATP

    		 GSK-3 Others
    6-Me-ATP (N6-Methyl-ATP) is a N 6-modified ATP derivative. 6-Me-ATP shows excellent binding affinity to GSK3, serving as the phosphate group donor for GSK3β-catalyzed phosphorylation of its substrate peptide .
    6-Me-ATP
  • HY-B2176R
    ATP (Standard)

    		Endogenous Metabolite Metabolic Disease Inflammation/Immunology
    ATP (Standard) is the analytical standard of ATP. This product is intended for research and analytical applications. ATP (Adenosine 5'-triphosphate) is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation . In Vitro: ATP (5 mM; 1 hour) co-treatment with LPS (1 μg/mL) has a synergistic effect on the activation of the NLRP3 inflammasome in HGFs .
    ATP (2 mM; 0.5-24 hours) induces secretion of IL-1β, KC and MIP-2 from BMDMs in a caspase-1 activation-dependent manner .
    ATP promotes neutrophil chemotaxis in vitro .
    In Vivo: ATP (50 mg/kg; i.p.) protects mice against bacterial infection in vivo .
    ATP induces the secretion of IL-1β, KC and MIP-2 and neutrophils recruitment in vivo .
    ATP (Standard)
  • HY-131787A
    2-Amino-ATP tetrasodium

    		Nucleoside Antimetabolite/Analog Others
    2-Amino-ATP tetrasodium is a substitute for ATP, produced by inserting an amino acid into the C2 position of ATP.
    2-Amino-ATP tetrasodium
  • HY-D2258
    Bio-17-ATP

    		Fluorescent Dye Others
    Bio-17-ATP is a substrate that can be used for AMPylation assays .
    Bio-17-ATP
  • HY-145249
    ATP-PEG8-Biotin

    		PROTAC Linkers Inflammation/Immunology
    ATP-PEG8-Biotin is a PEG-based linker that incorporates ATP. ATP is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation .
    ATP-PEG8-Biotin
  • HY-160764
    N6-Carboxymethyl-ATP

    		Drug Derivative Others
    N6-Carboxymethyl-ATP is the alkylation product of ATP with iodoacetic acid at pH 6.5, where alkylation of ATP with iodoacetic acid at pH 6.5 yielded 1-carboxymethyl-ATP which, after alkaline rearrangement gave N6-carboxymethyl-ATP .
    N6-Carboxymethyl-ATP
  • HY-108667
    TNP-ATP triethylammonium

    		P2X Receptor Others
    TNP-ATP triethylammonium is a selective P2X receptor antagonist. TNP-ATP triethylammonium shows antinociceptive effects in rats .
    TNP-ATP triethylammonium
  • HY-137626
    Sp-ATPαS

    		Biochemical Assay Reagents Others
    Sp-ATPαS is a regulator of ATP-binding proteins. Sp-ATPαS is metabolically more stable than ATP .
    Sp-ATPαS
  • HY-W010735R
    ATP (disodium salt hydrate) (Standard)

    		Endogenous Metabolite Metabolic Disease Inflammation/Immunology Cancer
    ATP (disodium salt hydrate) (Standard) is the analytical standard of ATP (disodium salt hydrate). This product is intended for research and analytical applications. ATP disodium salt hydrate (Adenosine 5'-triphosphatedisodium salt hydrate) is a central component of energy storage and metabolism in vivo, provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP disodium salt hydrate is an important endogenous signaling molecule in immunity and inflammation .
    ATP (disodium salt hydrate) (Standard)
  • HY-B2176
    ATP
    80+ Cited Publications

    Adenosine 5'-triphosphate

    		 Endogenous Metabolite Metabolic Disease Inflammation/Immunology
    ATP (Adenosine 5'-triphosphate) is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation .
    ATP
  • HY-136650
    Fludarabine triphosphate

    F-ara-ATP

    		 Nucleoside Antimetabolite/Analog Drug Metabolite DNA/RNA Synthesis Apoptosis Cancer
    Fludarabine triphosphate (F-ara-ATP), the active metabolite of Fludarabine (HY-B0069), is a potent, noncompetitive and specific inhibitor of DNA primase, with an IC50 of 2.3 μM and a Ki of 6.1 μM. Fludarabine triphosphate inhibits DNA synthesis by blocking DNA primase and primer RNA formation. Fludarabine triphosphate inhibits ribonucleotide reductase and DNA polymerase and ultimately leads to cellular apoptosis .
    Fludarabine triphosphate
  • HY-137325A
    2-Chloro-ATP sodium

    		Calcium Channel Metabolic Disease
    2-Chloro-ATP sodium (2-Chloro ATP) is an adenine nucleotide and an analog of ATP. It is an antagonist of the purinergic P2Y1 receptor and inhibits intracellular calcium mobilization induced by ADP (HY-W010918) in Jurkat cells expressing the human receptor (Ki=2.3 μM). 2-Chloro-ATP sodium is an agonist of the purinergic P2X receptor and induces inward currents in HEK293 cells expressing human bladder smooth muscle or rat PC12 forms of the receptor (EC50=0.5 and 2.5 μM). 2-Chloro-ATP sodium induces relaxation of precontracted guinea pig cecal strips in a concentration-dependent manner. 2-Chloro-ATP sodium has been used to study the substrate specificity of cyclic nucleotide-dependent protein kinases such as protein kinase A (PKA) and PKG.
    2-Chloro-ATP sodium
  • HY-150983
    ATP synthase inhibitor 2

    		ATP Synthase Bacterial Infection
    ATP synthase inhibitor 2 is a Pseudomonas aeruginosa (PA) ATP synthase inhibitor (IC50=10 μg/mL). ATP synthase inhibitor 2 can inhibit Pseudomonas aeruginosa (PA) ATP synthesis activity completely at 128 μg/mL .
    ATP synthase inhibitor 2
  • HY-137888A
    Oxidized ATP trisodium salt

    oATP trisodium salt

    		 P2X Receptor NOD-like Receptor (NLR) Inflammation/Immunology
    Oxidized ATP (oATP) trisodium salt is a broad-spectrum P2 receptor inhibitor. Oxidized ATP trisodium salt irreversibly antagonizes P2X7R activation. Oxidized ATP trisodium salt inhibits c-reactive protein (CRP)-induced NLRP3 inflammasome activation. Oxidized ATP trisodium salt can be used for research of atherosclerosis .
    Oxidized ATP trisodium salt
  • HY-131800A
    3'-Deoxy-3'-amino-ATP tetrasodium

    		Nucleoside Antimetabolite/Analog Others
    3'-Deoxy-3'-amino-ATP tetrasodium is an ATP substitute, produced by inserting an amino acid into the C3 position of ATP. 3'-Deoxy-3'-amino-ATP tetrasodium can catalyze RNA synthesis in the presence of RNA polymerase.
    3'-Deoxy-3'-amino-ATP tetrasodium
  • HY-B0345AS
    ATP-18O4 disodium salt

    		Endogenous Metabolite Metabolic Disease
    ATP- 18O4 (disodium salt) is the 18O labeled ATP disodium salt[1]. ATP disodium salt (Adenosine 5'-triphosphate disodium salt) is a central component of energy storage and metabolism in vivo, provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP disodium salt is an important endogenous signaling molecule in immunity and inflammation[2][3].
    ATP-18O4 disodium salt
  • HY-134393B
    6-Me-ATP (trisodium) solution (100mM)

    N6-Methyl-ATP (trisodium) solution (100mM)

    		 GSK-3 Others
    6-Me-ATP (N6-Methyl-ATP) trisodium solution (100mM) is a N 6-modified ATP derivative. 6-Me-ATP trisodium shows excellent binding affinity to GSK3, serving as the phosphate group donor for GSK3β-catalyzed phosphorylation of its substrate peptide .
    6-Me-ATP (trisodium) solution (100mM)
  • HY-101370
    2-Methylthio-ATP tetrasodium

    		P2X Receptor Metabolic Disease
    2-Methylthio-ATP tetrasodium is a non-specific P2-receptor agonist. 2-Methylthio-ATP tetrasodium causes noncompetitive inhibition of ADP-induced human platelet aggregation .
    2-Methylthio-ATP tetrasodium
  • HY-112715
    ATP synthase inhibitor 1

    		ATP Synthase Cardiovascular Disease
    ATP synthase inhibitor 1 is a potent inhibitor of c subunit of the F1/FO-ATP synthase complex, inhibits mitochondrial permeability transition pore (mPTP) opening, does not affect ATP levels .
    ATP synthase inhibitor 1
  • HY-150983A
    ATP synthase inhibitor 2 TFA

    		ATP Synthase Bacterial Infection
    ATP synthase inhibitor 2 (Compound 22) TFA is a Pseudomonas aeruginosa (PA) ATP synthase inhibitor (IC50=10 μg/mL). ATP synthase inhibitor 2 TFA can inhibit Pseudomonas aeruginosa (PA) ATP synthesis activity completely at 128 μg/mL .
    ATP synthase inhibitor 2 TFA
  • HY-136650A
    Fludarabine triphosphate trisodium
    1 Publications Verification

    F-ara-ATP trisodium

    		 Nucleoside Antimetabolite/Analog Drug Metabolite DNA/RNA Synthesis Apoptosis Cancer
    Fludarabine triphosphate (F-ara-ATP) trisodium, the active metabolite of Fludarabine (HY-B0069), is a potent, noncompetitive and specific inhibitor of DNA primase, with an IC50 of 2.3 μM and a Ki of 6.1 μM. Fludarabine triphosphate trisodium inhibits DNA synthesis by blocking DNA primase and primer RNA formation. Fludarabine triphosphate trisodium inhibits ribonucleotide reductase and DNA polymerase and ultimately leads to cellular apoptosis .
    Fludarabine triphosphate trisodium
  • HY-B2176B
    ATP dimagnesium
    80+ Cited Publications

    Adenosine 5'-triphosphate dimagnesium

    		 Endogenous Metabolite Inflammation/Immunology
    ATP (Adenosine 5'-triphosphate) dimagnesium is a central component of energy storage and metabolism in vivo. ATP dimagnesium provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP dimagnesium is an important endogenous signaling molecule in immunity and inflammation .
    ATP dimagnesium
  • HY-B2176E
    ATP magnesium

    Adenosine 5'-triphosphate magnesium

    		 Endogenous Metabolite Metabolic Disease Inflammation/Immunology
    ATP (Adenosine 5'-triphosphate) magnesium is a central component of energy storage and metabolism in vivo. ATP magnesium provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP magnesium is an important endogenous signaling molecule in immunity and inflammation .
    ATP magnesium
  • HY-B2176C
    ATP dipotassium

    Adenosine 5'-triphosphate dipotassium

    		 Endogenous Metabolite Metabolic Disease Inflammation/Immunology Cancer
    ATP dipotassium (Adenosine 5'-triphosphate dipotassium) is a central component of energy storage and metabolism in vivo. ATP dipotassium provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP dipotassium is an important endogenous signaling molecule in immunity and inflammation .
    ATP dipotassium
  • HY-B2176D
    ATP ditromethamine

    Adenosine 5'-triphosphate ditromethamine

    		 Endogenous Metabolite Metabolic Disease Inflammation/Immunology
    ATP ditromethamine (Adenosine 5'-triphosphate ditromethamine) is a central component of energy storage and metabolism in vivo. ATP ditromethamine provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP ditromethamine is an important endogenous signaling molecule in immunity and inflammation .
    ATP ditromethamine
  • HY-134440A
    α,β-Methylene-ATP

    		P2X Receptor Inflammation/Immunology
    α,β-Methylene ATP, a phosphonic analog of ATP, is a P2X3 and P2X7 receptor ligand. α,β-Methylene ATP is a highly selective agonist for P2X1 and P2X3, with practically no activity at P2X2,4-7 .
    α,β-Methylene-ATP
  • HY-150770S
    Adenosine 5'-triphosphate(ATP)-d4 ammonium salt

    		Isotope-Labeled Compounds Others
    Adenosine 5'-triphosphate(ATP)-d4 (ammonium salt) is the deuterium labeled Adenosine 5'-triphosphate(ATP) ammonium salt[1].
    Adenosine 5'-triphosphate(ATP)-d4 ammonium salt
  • HY-137325
    2-Chloro-ATP

    		Guanylate Cyclase Others
    2-Chloro-ATP is a soluble guanylate cyclase inhibitor that increases intracellular calcium concentration at low concentrations through a mechanism independent of inositol phosphate production .
    2-Chloro-ATP
  • HY-155752
    3′-O-Benzoyl-ATP

    3′-O-Benzoyladenosine 5′-triphosphate

    		 Drug Derivative Others
    3′-O-Benzoyl-ATP is O-Benzoyl modified guanosine triphosphate (ATP) .
    3′-O-Benzoyl-ATP

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