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Analogues

" in MedChemExpress (MCE) Product Catalog:

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By Research Areas:	Cancer (375) Cardiovascular Disease (67) Endocrinology (91) Infection (165) Inflammation/Immunology (93) Metabolic Disease (102) Neurological Disease (117)
Click Chemistry:	ADC Synthesis (2) Labeling and Fluorescence Imaging (1) DBCO (1) PROTAC Synthesis (2) Azide (41) Tetrazine (1) Alkynes (17)
Oligonucleotides:	Nucleotides and their Analogs (1) Nucleosides and their Analogs (326) Nucleoside Phosphoramidites (2) MicroRNAs (2) Cationic Lipids (5) Cap Analogs (15) Cap 1 (4) Cap 0 (3)

1330

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

192

Peptides

Inhibitory Antibodies

109

Natural
Products

Isotope-Labeled Compounds

Click Chemistry

351

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-134356

AICA-riboside, 5′-phosphate AICAR-5'-MP	Endogenous Metabolite	Others
AICA-riboside, 5′-phosphate (AICAR-5'-MP) is a 5'-phosphorylated analogue of AICAR. AICAR is an adenosine analog and a AMPK activator. .

HY-124479A

γ-Lumicolchicine	Others	Cancer
γ-Lumicolchicine is an inactive analogue of Colchicine (HY-16569)

HY-P3314

Nendratareotide	Somatostatin Receptor	Metabolic Disease
Nendratareotide is a somatostatin analogue .

HY-115577

Mitochonic acid 35	Others	Others
Mitochonic acid 35 is an IAA analogue with cytoprotective effects .

HY-130777

AMP-PNP Adenylyl imidodiphosphate	Biochemical Assay Reagents	Others
AMP-PNP (Adenylyl imidodiphosphate) is a non-hydrolysable ATP analogue .

HY-131812

5'-dAMPS 2'-Deoxyadenosine 5'-O-thiophosphate	Others	Others
5'-dAMPS is an analogue of 5'-dAMP and thus a potential substrate, competitive inhibitor or regulator of enzymes that interact with dAMP .

HY-135654

hDHODH-IN-2	Dihydroorotate Dehydrogenase DNA/RNA Synthesis	Inflammation/Immunology
hDHODH-IN-2 is an analogue of the active metabolite of Leflunomide. hDHODH-IN-2 is a human dihydroorotate dehydrogenase (hDHODH) inhibitor. hDHODH-IN-1 has anti-inflammatory activity .

HY-P3659

(D-Phe7)-α-MSH	Melanocortin Receptor	Cancer
(D-Phe7)-α-MSH is an α-MSH analogue .

HY-158110

Phenylcapsaicin	TRP Channel	Inflammation/Immunology
Phenylcapsaicin is an analogue of Capsaicin (HY-10448). Phenylcapsaicin is a TRPV1 receptor activator. Phenylcapsaicin enhances fat oxidation during aerobic exercise .

HY-W710914A

rel-HDMP 28 hydrochloride	Serotonin Transporter	Neurological Disease
rel-HDMP 28 hydrochloride (Compound 2g) is a methylphenidate analogue that binds selectively to SERT (K_i = 105 nM)_[1].

HY-131598

6-Thio-GTP 6-Thioguanosine-5'-triphosphate	Others	Inflammation/Immunology Cancer
6-Thio-GTP is an analogue of GTP, and a metabolite of an immunosuppressive drug, Azathioprine (HY-B0256) .

HY-125420

5-Deazaisofolic acid	Others	Cancer
5-Deazaisofolic acid is an isofolate analogue with antitumor activity. 5-Deazaisofolic acid can be utilized in cancer research .

HY-146748

Sorbicillin	Others	Inflammation/Immunology
Sorbicillin, a sorbicillinoid analogue, acts as a potent anti-inflammation agent .

HY-123259

CB3731	Others	Others
CB3731 is an analogue of N-10-(fluoroethyl)quinazolinylfolate and can be used for fluorine-19 nuclear magnetic resonance studies of binary and ternary complexes of thymidylate synthase .

HY-W412313

Methyl 3,5-di-O-(2,4-dichlorobenzyl)-D-ribofuranoside	Nucleoside Antimetabolite/Analog	Others
Methyl 3,5-di-O-(2,4-dichlorobenzyl)-D-ribofuranoside is a ribofuranose nucleoside analogue.

HY-101362

QX-222 chloride	Sodium Channel	Neurological Disease
QX-222 chloride, a trimethyl analogue of Lignocaine (HY-B0185), is a potent Na ⁺ channel blocker .

HY-135591

Methyl Raloxifene 4'-(2,3,4-Tri-O-acetyl-β-D-glycopyranuronate)	Others	Others
Methyl Raloxifene 4'-(2,3,4-Tri-O-acetyl-β-D-glycopyranuronate) is an analogue of Raloxifene 4'-glucuronide.

HY-147787

Urease-IN-3	Bacterial	Infection
Urease-IN-3 (Compound L12) is a potent inhibitor of Urease with an IC₅₀ of 1.449 μM. Urease-IN-3 is a flavonoid analogue compound .

HY-N7256

Dihydrocephalomannine	Microtubule/Tubulin	Cancer
Dihydrocephalomannine (compound 1b), an analogue of Paclitaxel, shows reduced cytotoxicity and tubulin binding compared to Paclitaxel .

HY-146744

Antileishmanial agent-4	Parasite	Infection
Antileishmanial agent-4 is a ribonucleoside analogue and acts as an antileishmanial agent .

HY-N2012

7-Hydroxyaristolochic acid A	Others	Inflammation/Immunology
7-Hydroxyaristolochic acid A is an aristolochic acid analogue found in Aristolochia plants. Aristolochic acid can be used as an anti-inflammatory agent .

HY-103324

Palmitoylisopropylamide PIA	Others	Metabolic Disease
Palmitoylisopropylamide is a Palmitoylethanolamide analogue inhibits [ ³H]-Anandamide metabolism with a pI₅₀ of 4.89 .

HY-124938

ABC-1	Antibiotic	Infection
ABC-1 is a phosphorylated analogue and a potential antiviral agent against Newcastle disease virus (NDV). ABC-1 has potent antiviral activity .

HY-152982

1-(2-C-β-Methyl-β-D-ribofuranosyl)-5-nitropyridine-2(1H)-one	Nucleoside Antimetabolite/Analog	Others
1-(2-C-β-Methyl-β-D-ribofuranosyl)-5-nitropyridine-2(1H)-one is a nitropyridine nucleoside analogue.

HY-108776

(Rac)-sn-Glycerol 3-phosphate sodium DL-α-Glycerol phosphate sodium	Endogenous Metabolite	Inflammation/Immunology
(Rac)-sn-Glycerol 3-phosphate sodium is an a-site substrate analogue. (Rac)-sn-Glycerol 3-phosphate sodium is bound to the a-site, the rate of reaction of indole and nucleophilic indole analogues with E(A-A) is strongly inhibited .

HY-113128C

(Rac)-sn-Glycerol 3-phosphate DL-α-Glycerol phosphate	Endogenous Metabolite	Others
(Rac)-sn-Glycerol 3-phosphate is an a-site substrate analogue. (Rac)-sn-Glycerol 3-phosphate is bound to the a-site, the rate of reaction of indole and nucleophilic indole analogues with E(A-A) is strongly inhibited .

HY-156282

Antibacterial agent 158	Bacterial	Infection
Antibacterial agent 158 (compound 6c), a Micrococcin analogue, and is effective against impetigo and C. difficile infection (CDI) .

HY-23171

1,2-Di-O-acetyl-5-O-benzoyl-3-deoxy-3-fluoro-D-ribofuranose	Nucleoside Antimetabolite/Analog	Others
1,2-Di-O-acetyl-5-O-benzoyl-3-deoxy-3-fluoro-D-ribofuranose is a ribofuranose nucleoside analogue.

HY-154321

Methyl 2-deoxy-3,5-di-O-benzoyl-2-fluoro-4-thio-D-arabinopentofuranoside	Nucleoside Antimetabolite/Analog	Others
Methyl 2-deoxy-3,5-di-O-benzoyl-2-fluoro-4-thio-D-arabinopentofuranoside is a ribofuranose nucleoside analogue.

HY-16395

PG-11047 CGC-11047	Others	Cancer
PG-11047 (CGC-11047) is a polyamine analogue. PG-11047 can be used for the research of breast cancer .

HY-131773

2-Cl-5'-AMP	Others	Others
2-Cl-5'-AMP is a 5'-AMP analogue and can be used for receptor mapping research .

HY-131810

5'-AMPS	Others	Others
5'-AMPS is an analogue of 5'-AMP and a substrate and competitive inhibitor or regulator of enzymes that interact with 5'-AMP .

HY-121241

Dehydroemetine	Parasite	Infection
Dehydroemetine, a synthetic analogue of emetine dihydrochloride, is used for visceral leishmaniasis. Dehydroemetine used for anti-parasites .

HY-16027

Acyline	GnRH Receptor	Endocrinology
Acyline, a GnRH peptide analogue, is a GnRH antagonist that inhibits gonadotropin and testosterone (T) levels .

HY-131846

6-Cl-5'-PuMP 6-Chloropurine 5'-ribonucleotide	Others	Others
6-Cl-5'-PuMP is a reactive analogue of adenosine 5’-O-monophosphate (5’-AMP), and is suitable for modifying position 6 using various nucleophiles .

HY-A0005

Clofarabine 4 Publications Verification	Nucleoside Antimetabolite/Analog Autophagy Apoptosis	Metabolic Disease Cancer
Clofarabine, a nucleoside analogue for research of cancer, is a potent inhibitor of ribonucleotide reductase (IC₅₀=65 nM) by binding to the allosteric site on the regulatory subunit .

HY-117582

Elvucitabine	Reverse Transcriptase HIV	Infection
Elvucitabine is an L-nucleoside analogue. Elvucitabine is a potent nucleoside reverse transcriptase (RT) inhibitor. Elvucitabine can be used in research of viral infection .

HY-131814

5'-dGMPS	Others	Others
5'-dGMPS is an analogue of 5'-dGMP and a potential substrate, competitive inhibitor or regulator of enzymes that interact with 5'-dGMP .

HY-131815

5'-dIMPS	Others	Others
5'-dIMPS is an analogue of 5'-dIMP and a potential substrate, competitive inhibitor or regulator of enzymes that interact with 5'-dIMP .

HY-131813

5'-dCMPS 2'-Deoxycytidine 5'-monophosphate	Others	Others
5'-dCMPS is an analogue of 5'-dCMP and a potential substrate, competitive inhibitor or regulator of enzymes that interact with 5'-dCMP .

HY-16027A

Acyline TFA	GnRH Receptor	Endocrinology
Acyline TFA, a GnRH peptide analogue, is a GnRH antagonist that inhibits gonadotropin and testosterone (T) levels .

HY-160080

Creatinol hemisulfate	Others	Others
Creatinol (hemisulfate) is the N-ethyl analogue of creatine. Creatinol (hemisulfate) can be used for various researches .

HY-141472

7-Methylguanosine 5'-diphosphate sodium 7-Methyl-GDP sodium; m7GDP sodium	Endogenous Metabolite	Others
7-Methylguanosine 5'-diphosphate (7-Methyl-GDP) sodium, a cap analog, can be used in the synthesis of mRNA cap analogues .

HY-134340

8-pMeOPT-2'-O-Me-cAMP 8-(4-Methoxyphenylthio)-2'-O-Me-cAMP	Others	Others
8-pMeOPT-2'-O-Me-cAMP is an analogue of the signal molecule cAMP and a potent stimulator of exchange factors activated by cAMP (Epac), while it doesn't activate PKA as cAMP does .

HY-P3553

Alsactide	Melanocortin Receptor	Neurological Disease
Alsactide, a heptadecapeptide analogue, is an adrenocorticotropic hormone (ACTH) agonist. Alsactide can be used in research of central nervous system .

HY-119929

B 669	Bacterial	Infection
B 669, a c10fazimine analogue, is an antimicrobial agent. B 669 has the activity against Mycobacterium ieprae .

HY-152974

1-(2,3,5-Tri-O-benzoyl-2-C-β-methyl-β-D-ribofuranosyl)-5-nitropyridine-2(1H)-one	Nucleoside Antimetabolite/Analog	Others
1-(2,3,5-Tri-O-benzoyl-2-C-β-methyl-β-D-ribofuranosyl)-5-nitropyridine-2(1H)-one is a nitropyridine nucleoside analogue.

HY-123396

8-Chloro-cAMP	PKA	Cancer
8-Chloro-cAMP is a cAMP analogue that induces growth arrest, and modulates cAMP-dependent PKA activity. 8-Chloro-cAMP has anticancer activity .

HY-136647

8-Bromoadenosine 5'-triphosphate tetrasodium 8-Br-ATP tetrasodium	Others	Others
8-Bromoadenosine 5'-triphosphate tetrasodium (8-Br-ATP tetrasodium) is an ATP analogue. ATP is a central component of energy storage and metabolism in vivo .

HY-128866

TBAJ-876	Bacterial	Infection
TBAJ-876 is the inhibitor of mycobacterium tuberculosis. TBAJ-876 is the analogue of the anti-tuberculosis agent Bedaquiline. TBAJ-876 has the potential for the research of tuberculosis .

Cat. No.	Product Name

HY-L044

Nucleotide Compound Library

536 compounds

Nucleoside and nucleotide analogues are synthetic, chemically modified compounds that have been developed to mimic their physiological counterparts in order to exploit cellular metabolism and subsequently be incorporated into DNA and RNA to inhibit cellular division and viral replication. In addition to their incorporation into nucleic acids, nucleoside and nucleotide analogues can interact with and inhibit essential enzymes such as human and viral polymerases (that is, DNA-dependent DNA polymerases, RNA-dependent DNA polymerases or RNA-dependent RNA polymerases), kinases, ribonucleotide reductase, DNA methyltransferases, purine and pyrimidine nucleoside phosphorylase and thymidylate synthase. These actions of nucleoside and nucleotide analogues have potential therapeutic benefits — for example, in the inhibition of cancer cell growth, the inhibition of viral replication as well as other indications.

MCE offers a unique collection of 536 nucleotide compounds including nucleotide, nucleoside and their structural analogues. MCE Nucleotide Compound Library is a useful tool to discover anti-cancer and antiviral drugs for high throughput screening (HTS) and high content screening (HCS).

HY-L043

Lipid Compound Library

1,441 compounds

Lipids are a diverse and ubiquitous group of compounds which have many key biological functions, such as acting as structural components of cell membranes, serving as energy storage sources and participating in signaling pathways. Several studies suggest that bioactive lipids have effects on the treatment of some mental illnesses and metabolic syndrome. For example, DHA and EPA are important for monoaminergic neurotransmission, brain development and synaptic functioning, and are also correlated with a reduced risk of cancer and cardiovascular disease in clinical and animal studies.

MCE supplies a unique collection of 1,441 lipid and lipid derivative related compounds including triglycerides, phospholipids, sphingolipids, steroids and their structural analogues or derivatives. MCE lipid compound library can be used for research in bioactive lipids, and high throughput screening (HTS) and high content screening (HCS).

HY-L0117V

Asinex Macrocycles for Glycomimetics Library

1,412 compounds

Glycomimetics are designed to mimic the structure of natural carbohydrates and modulate their disease-related functions. Macrocyclic glycomimetics are an extremely interesting class of glycomimetics as they occupy space between small and macro molecules. Macrocyclic glycomimetics are mostly represented by naturally occurring molecules derived from marine microorganisms and bacterial or fungal metabolites.

HY-L0119V

Asinex PPI Pre-Plated Library

3,253 compounds

Protein protein interactions (PPI) have pivotal roles in life processes. The studies showed that aberrant PPI are associated with various diseases. However, the design of modulators targeting PPI still faces tremendous challenges, such the difficult PPI interfaces for the drug design, lack of ligands reference, lack of guidance rules for the PPI modulators development and high-resolution PPI proteins structures.

The PPI Library comprises molecules of various sizes, frameworks, and shapes ranging from fragment-like entities to macrocyclic derivatives designed as secondary structure mimetics or as epitope mimetics. The designs cover β-turn / loop mimetics and α-helix mimetics. Since helices present at the interface in 62% of all protein-protein interactions. This library focused on designs including mimics with the substitution geometry of an a-helices, as well as designs that mimic the location of “hot-spot” side chains in helix-mediated PPIs.

HY-L0120V

Asinex BioDesign Library

170,269 compounds

“BioDesign” approach incorporates key structural features of known pharmacologically relevant natural products (e.g. alkaloids and other secondary metabolites) into synthetically feasible medicinal chemistry scaffolds. In order to identify the privileged pharmacophores, ring systems and linkers, we have carried out statistical analysis of structural features of natural products, marketed drugs, and drug candidates.

Saturated, fused ring, spiro, and bridged systems with a tendency towards multiple chiral centers are highly privileged among natural products and marketed drugs yet these structures are very poorly represented in commercial libraries. This library addressed this market need by incorporating these privileged elements into the design of novel synthetic molecules with high molecular framework diversity, multiple stereogenic centers (≥2), and degree of saturation (Fsp3 > 0.5).

HY-L0118V

Asinex Covalent Inhibitors Library	8,085 compounds
A unique set of molecules containing mild electrophilic moieties that covalently interact with amino acid residues in the target protein. The diversity of our compounds for covalent drug discovery ranges from natural product-like scaffolds to macrocycles, creating multiple opportunities in hit generation for a selected target.

HY-L0116V

Asinex Macrocycles for RNA Library

1,065 compounds

Macrocycles are promising scaffolds for the design of novel RNA targeting molecules. This collection of macrocycles for RNA consists of very diverse, drug-like molecules which incorporate certain known RNA-recognition elements (e.g. nucleobase ring systems and analogs) distributed within macrocyclic rings or peripheral fragments. As macrocyclic molecules tend to be larger than traditional screening molecules, it is vital to carefully assess and control their physicochemical properties. All macrocycles have been tested for aqueous and DMSO solubility with cutoffs applied at 10 mM in DMSO and 50 µM in PBS (pH 7.4); PAMPA permeability has also been tested for representative set of macrocycles.

HY-L0115V

Asinex Macrocycles Library

10,091 compounds

ASINEX has elaborated a library of diverse macrocycles using an effective tool box of synthetic methods. The resulting scaffolds are novel, tremendously diverse, medchem-relevant, macrocyclic frameworks.

Macrocyles tend to be larger than traditional screening molecules which make them perfect discovery tools for targets with shallow or extended binding sites. At the same time, their unique character based on restricted flexibility and ability to form intra-molecular hydrogen bonds allows for design approaches effectively optimizing properties such asaqueous solubility and membrane permeability. Many of these macrocycles have been tested for aqueous and DMSO solubility with cut-offs applied at 10 mM in DMSO and 50 µM in PBS (pH 7.4) followed by PAMPA permeability assay.

Cat. No.	Product Name	Type

HY-113870

6-NBDG	Fluorescent Dyes/Probes
6-NBDG is a fluorescent glucose analogue, it can be used for fluorescence imaging and monitoring glucose transport and uptake. 6-NBDG can be used as a fluorescent probe for detecting macrophage-rich atherosclerotic plaques .

HY-D1574

C6 NBD Sphingomyelin	Fluorescent Dyes/Probes
C6 NBD Sphingomyelin is a fluorescent short-chain analogue of Sphingomyelin (HY-113498). Chlamydia trachomatis acquires C6 NBD Sphingomyelin endogenously synthesizes from C6-NBD-ceramide and transportes to the chlamydial inclusion. C6 NBD Sphingomyelin can incorporate into the plasma membrane .

HY-135638

Imatinib Acid	Fluorescent Dyes/Probes
Imatinib Acid, an analogue of Imatinib, is usually used as a labeled chemical or fluorescent probe.

HY-112641A

AkaLumine hydrochloride 1 Publications Verification	Chromogenic Substrates
AkaLumine hydrochloride is a luciferin analogue, with a K_m of 2.06 μM for recombinant Fluc protein.

HY-D1424

Coelenterazine hcp	Fluorescent Dyes/Probes
Coelenterazine hcp is a Coelenterazine analogue. Coelenterazine hcp shows high sensitivity to Ca ²⁺. Coelenterazine hcp is suited for monitoring intracellular Ca ²⁺ .

HY-147114

3-Methyl-8-(2'-deoxy-β-D-ribofuranosyl)isoxanthopterin	Fluorescent Dyes/Probes
3-Methyl-8-(2'-deoxy-β-D-ribofuranosyl)isoxanthopterin is a DNA uptake tracer, a pteridine-based fluorescent guanosine analogue. 3-Methyl-8-(2'-deoxy-β-D-ribofuranosyl)isoxanthopterin is widely used in studies of DNA binding and dynamics, with an absorbance maximum at 350 nm and an emission maximum at 430 nm .

HY-D0147

Resorufin pentyl ether Pentoxyresorufin	Fluorescent Dyes/Probes
Resorufin pentyl ether (Pentoxyresorufin) is a Resazurin (HY-111391) analogue. Resorufin pentyl ether can function as a substrate probe to characterize and differentiate between a variety of inducers of cytochromes P-450. Resorufin pentyl ether has bactericidal activity against N. gonorrhoeae .

HY-D2263

BODIPY-cholesterol conjugate-3	Dyes
BODIPY-cholesterol conjugate-3 (compound 7) is a cholesterol analogue with a fluorescent BODIPY group. BODIPY-cholesterol conjugate-3 can be used to simultaneously visualize multiple cholesterol pools in cells, as it is primarily localized to the plasma membrane .

HY-135637

Nilotinib Acid	Fluorescent Dyes/Probes
Nilotinib Acid, an analogue of Nilotinib, is usually used as a labeled chemical or fluorescent probe.

HY-163140

IL-33 probe-1	Fluorescent Dyes/Probes
IL-33 probe-1 is a fluorescent analogue of the interleukin IL-33_[1].

HY-D1340

Sulfo-Cyanine7 maleimide potassium	Fluorescent Dyes/Probes
Sulfo-Cyanine7 maleimide potassium is an analogue of Cy7 maleimide and a hydrophilic near-infrared fluorescent dye.

HY-135634

GNF-2-PEG-acid	Fluorescent Dyes/Probes
GNF-2-PEG-acid, an analogue of GNF-2, is usually used as a labeled chemical or fluorescent probe.

HY-D1582

C12 NBD Phytoceramide	Chromogenic Substrates
C12 NBD Phytoceramide, a ceramide analogue, is a fluorescent substrate, can be used to detect ceramidase activity .

HY-141575

C12-NBD-ceramide	Fluorescent Dyes/Probes
C12-NBD-ceramide is a fluorescent analogue of ceramide, it can be used as a substrate in ceramidase assays .

HY-135635

ABL-001-Amide-PEG3-acid	Fluorescent Dyes/Probes
ABL-001-Amide-PEG3-acid, an analogue of ABL-001, is usually used as a labeled chemical or fluorescent probe.

HY-103470

K114	Fluorescent Dyes/Probes
K114, a fluorescent Congo Red analogue, binds tightly to amyloid fibrils with an EC₅₀ of 20-30 nM . K114 is an efficient detector of semen-derived enhancer of virus infection (SEVI) .

HY-D1119C

AF647-NHS ester triTEA	Fluorescent Dyes/Probes
AF647-NHS ester is an analogue of Alexa Fluor 647 (AF647), which has excitation wavelength (λ_ex) of 635 nm (conventional fluorescence detection)/620 nm (instantaneous detection) .

HY-135636

Ponatinib Acid	Fluorescent Dyes/Probes
Ponatinib Acid, an analogue of Ponatinib, is usually used as a labeled chemical or fluorescent probe. Ponatinib Acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-124013

NBDA 4-(α-N-L-alanine)-NBD	Fluorescent Dyes/Probes
NBDA (4-(α-N-L-alanine)-NBD) is a structural and functional analogue of the 2,4-dinitrophenyl group (DNP). NBDA can be used to detect and characterize antinitroaromatic antibodies, even in crude preparations, and possibly on cell surfaces .

HY-148073

MeO-Succ-Arg-Pro-Tyr-AMC	Chromogenic Substrates
MeO-Succ-Arg-Pro-Tyr-AMC is an analogue of 7-amido-4-methylcoumarin (HY-D0027). MeO-Succ-Arg-Pro-Tyr-AMC is a sensitive fluorescent substrate chymotrypsin-like protease. (λ_ex=341 nm, λ_em=441 nm).

HY-120959

DAUDA	Fluorescent Dyes/Probes
DAUDA (11-(dansylamino) undecanoic acid) is an environment-sensitive fluorescent fatty acid analogue. DAUDA alters its intensities and fluorescent emission spectra on entry into binding proteins. DAUDA is used to determine the relative affinity of natural fatty acids for polymorphs of the Schistosoma mansoni Sm14 fatty acid-binding protein[1].

HY-D1119A

AF647-NHS ester tripotassium	Fluorescent Dyes/Probes
AF647-NHS ester (tripotassium) is an analogue of Alexa Fluor 647 (AF647) (HY-D1119). AF647 is a bright, far-red fluorescent dye with an excitation wavelength (λ_ex) of 635 nm (conventional fluorescence detection)/620 nm (instantaneous detection). Storage: protect from light .

HY-D1119B

AF647-NHS ester trisodium	Fluorescent Dyes/Probes
AF647-NHS ester (trisodium) is an analogue of Alexa Fluor 647 (AF647) (HY-D1119). AF647 is a bright, far-red fluorescent dye with an excitation wavelength (λ_ex) of 635 nm (conventional fluorescence detection)/620 nm (instantaneous detection). Storage: protect from light .

HY-D1540

Cyanine5.5 amine Cy 5.5 amine; Lumiprobe Cy 5.5 amine	Fluorescent Dyes/Probes
Cyanine5.5 amine (Cy 5.5 amine), a Cy5.5 Analogue, is a near-infrared (NIR) fluorescent dye (Ex=648 nm, Em=710 nm). Cyanine5.5 amine can be used in the preparation of Cy5.5-labeled nanoparticles, which can be tracked and imaged with low fluorescence background using confocal microscopy .

HY-D0815

Propidium Iodide

45+ Cited Publications

Fluorescent Dyes/Probes

Propidium Iodide (PI) is a nuclear staining agent that stains DNA. Propidium Iodide is an analogue of ethidine bromide that emits red fluorescence upon embedding in double-stranded DNA. Propidium Iodide cannot pass through living cell membranes, but it can pass through damaged cell membranes to stain the nucleus. Propidium Iodide has a fluorescence wavelength of 493/617 nm and a wavelength of 536/635 nm after Mosaic with DNA. Propidium Iodide is commonly used in the detection of apoptosis (apoptosis) or necrosis (necrosis), and is often used in flow cytometry analysis.

Cat. No.	Product Name	Type

HY-D0183

ATP-polyamine-biotin 1 Publications Verification	Enzyme Substrates
ATP-polyamine-biotin, the first cell-permeable ATP analogue, is an efficient kinase cosubstrate. ATP-polyamine-biotin promotes biotin labeling of kinase substrates in live cells .

HY-D0852

Sodium orthovanadate 5+ Cited Publications	Cell Assay Reagents
Sodium orthovanadate is an inhibitor of protein tyrosine phosphatases, alkaline phosphatases and a number of ATPases, most likely acting as a phosphate analogue.

HY-130777

AMP-PNP Adenylyl imidodiphosphate	Gene Sequencing and Synthesis
AMP-PNP (Adenylyl imidodiphosphate) is a non-hydrolysable ATP analogue .

HY-150145A

Cy5-UTP sodium (10mM in Water)	Gene Sequencing and Synthesis
Cy5-UTP sodium (10mM in Water) is a cyanine5-labeled UTP analogue that can produce fluorescent probes in vitro transcription reactions with excitation/emission wavelengths of 650/665 nm. Cy5-UTP sodium can be used in FISH, polychromatic fluorescence analysis, especially the two-color expression array combined with Cy5-UTP .

HY-100767

Guanylyl Imidodiphosphate trisodium Guanosine 5'-[β,γ-imido]triphosphate trisodium	Gene Sequencing and Synthesis
Guanylyl Imidodiphosphate (Guanosine 5'-[β,γ-imido]triphosphate) trisodium is a non-hydrolysable GTP analogue, an activator of ADP-ribosylation factor (ARF) and a potent stimulator of adenylate cyclase. Imidodiphosphate trisodium can be used in protein synthesis studies .

HY-153379

*ALC-0315 analogue-1*	Drug Delivery
ALC-0315 analogue-1 (compound P-10) is a cationic lipid. ALC-0315 analogue-1 is the raw material for synthesis of cationic liposome .

HY-153389

*ALC-0315 analogue-3*	Drug Delivery
ALC-0315 analogue-3 (compound P-35) is a liposome raw material. ALC-0315 analogue-3 can improve the loading rate and transport rate of nucleic acid drugs .

HY-153380

*ALC-0315 analogue-2*	Drug Delivery
ALC-0315 analogue-2 is an analogue of ALC-0315. ALC-0315 is an ionisable aminolipid that is responsible for mRNA compaction and aids mRNA cellular delivery and its cytoplasmic release through suspected endosomal destabilization. ALC-0315 can be used to form lipid nanoparticle (LNP) delivery vehicles. Lipid-Nanoparticles have been used in the research of mRNA COVID-19 vaccine.

HY-W155121

Big CHAP N,N-Bis(3-D-gluconamidopropyl)cholamide	Surfactants
Big CHAP are aqueous micelles of anionic cholate analogues .

HY-144003

BAY-R 1005	Drug Delivery
BAY-R 1005, an immunoenhancing agent, is a synthetic glycolipid analogue (GLA), which is supposed to modulate antibody synthesis .

HY-W127629

MOBS	Biochemical Assay Reagents
MOBS is an amphoteric buffer, a butane analogue of the Good buffers MOPS [3-(N-morpholino) propanesulfonic acid] and MES [2-(N-morpholino) ethanesulfonic acid] .

HY-W011517

2-Fluoroadenosine 2FA	Biochemical Assay Reagents
2-Fluoroadenosine (2FA) is a nucleoside analogue. 2-Fluoroadenosine has antibacterial activity with IC₅₀ value of 0.842 mM for Vibrio microvibrio .

HY-W394106

5-Hydroxymethyl uridine	Biochemical Assay Reagents
5-Hydroxymethyl uridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .

HY-W002039

3-Amino-3-phenylpropionic acid DL-β-Phenylalanine	Biochemical Assay Reagents
3-Amino-3-phenylpropionic acid (DL-β-Phenylalanine) is a structural GABA analogue. 3-Amino-3-phenylpropionic acid inhibits baclofen (HY-B0007) induced gastric acid secretion .

HY-117813

2-Thiouridine	Gene Sequencing and Synthesis
2-Thiouridine (2-Thioxo-2-deoxouridine) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .

HY-134421

2-Butenoyl coenzyme A lithium	Enzyme Substrates
2-Butenoyl coenzyme A (lithium), an active compound, can be used as a substrate for plasmodium falciparum enyl-ACP reductases and other enyl-CoA reductases. 2-Butenoyl coenzyme A lithium can be used as a substrate analogue to study the kinetics of β-hydroxyacyl-acyl-carrier protein (ACP) dehydratase (FabZ) .

HY-B0445A

NAD sodium Maximum Cited Publications 23 Publications Verification β-DPN sodium; β-NAD sodium; β-Nicotinamide Adenine Dinucleotide sodium	Enzyme Substrates
NAD (β-Nicotinamide Adenine Dinucleotide) sodium is an analogue of NAD. NAD sodium can be reduced to β-nicotinamide adenine dinucleotide (NADH) during coupling with reactions which oxidize organic substrates. NAD sodium can be converted to β-nicotinamide adenine dinucleotide (NADH) and passes to the inside of mitochondria that indirectly generates ATP .

HY-145798

N1,N3,N5-Tris(4-dodecylhexadecyl)benzene-1,3,5-tricarboxamide	Drug Delivery
N1,N3,N5-Tris(4-dodecylhexadecyl)benzene-1,3,5-tricarboxamide is an analogue of TT3 (HY-148049). TT3 is an ionizable lipid-like materials for mRNA and CRISPR/Cas9 delivery .

HY-145973A

3'OMe-m7GpppAmpG ammonium m7(3'OMeG)(5')ppp(5')(2'OMeA)pG ammonium	Gene Sequencing and Synthesis
3'OMe-m7GpppAmpG ammonium is a trinucleotide Cap analogue. 3'OMe-m7GpppAmpG ammonium shows a significant translational efficiency. 3'OMe-m7GpppAmpG ammonium can be used as a potential molecular biology tool in the field of mRNA vaccines and mRNA transfection, such as protein production, gene therapy and anti-cancer immunization .

HY-145789

Difluorocyclooctyne-CH2-benzoic acid

Indicators

Difluorocyclooctyne-CH2-benzoic acid is a Difluorinated cyclooctyne (DIFO) analogue that can be used for imaging glycans on live cells. Difluorinated cyclooctyne (DIFO) reagents rapidly reacts with azides in living cells without the need for copper catalysis . Difluorocyclooctyne-CH2-benzoic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-145790

Difluorocyclooctyne-CH2-COOH

Indicators

Difluorocyclooctyne-CH2-COOH is a Difluorinated cyclooctyne (DIFO) analogue that can be used for imaging glycans on live cells. Difluorinated cyclooctyne (DIFO) reagents rapidly reacts with azides in living cells without the need for copper catalysis . Difluorocyclooctyne-CH2-COOH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Cat. No.	Product Name	Target	Research Area

HY-P99735

Mipeginterferon alfa-2b	IFNAR	Infection
Mipeginterferon alfa-2b is an interferon alpha-2b (IFNA2b) analogue, with an average number of 5 substituted among 11 amino groups (one N-terminal and 10 lysine N6). Mipeginterferon alfa-2b has the relative molecular mass of 40 kDa .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-134356

AICA-riboside, 5′-phosphate AICAR-5'-MP	Structural Classification Human Gut Microbiota Metabolites Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
AICA-riboside, 5′-phosphate (AICAR-5'-MP) is a 5'-phosphorylated analogue of AICAR. AICAR is an adenosine analog and a AMPK activator. .

HY-N7256

Dihydrocephalomannine	Other Terpenoids Structural Classification Classification of Application Fields Terpenoids Source classification Plants Cephalotaxaceae Disease Research Fields Cancer Cephalotaxus fortunei Hooker	Microtubule/Tubulin
Dihydrocephalomannine (compound 1b), an analogue of Paclitaxel, shows reduced cytotoxicity and tubulin binding compared to Paclitaxel .

HY-N2012

7-Hydroxyaristolochic acid A	Structural Classification Monophenols Classification of Application Fields Ketones, Aldehydes, Acids Source classification Phenols Aristolochia Plants Aristolochiaceae Inflammation/Immunology Disease Research Fields	Others
7-Hydroxyaristolochic acid A is an aristolochic acid analogue found in Aristolochia plants. Aristolochic acid can be used as an anti-inflammatory agent .

HY-113128C

(Rac)-sn-Glycerol 3-phosphate DL-α-Glycerol phosphate	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
(Rac)-sn-Glycerol 3-phosphate is an a-site substrate analogue. (Rac)-sn-Glycerol 3-phosphate is bound to the a-site, the rate of reaction of indole and nucleophilic indole analogues with E(A-A) is strongly inhibited .

HY-141472

7-Methylguanosine 5'-diphosphate sodium 7-Methyl-GDP sodium; m7GDP sodium	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
7-Methylguanosine 5'-diphosphate (7-Methyl-GDP) sodium, a cap analog, can be used in the synthesis of mRNA cap analogues .

HY-N2387

Pinosylvin	Infection Structural Classification Stilbenes Classification of Application Fields Polygonaceae Reynoutria japonica Houtt. Source classification Phenols Polyphenols Plants Disease Research Fields	Bacterial Apoptosis Autophagy
Pinosylvin is a?pre-infectious stilbenoid toxin?isolated from the heartwood of Pinus species, has anti-bacterial activities . Pinosylvin is a resveratrol analogue, can induce cell apoptosis and autophapy in leukemia cells .

HY-B0255

Adefovir dipivoxil 1 Publications Verification GS 0840	Infection Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Cancer	HBV Reverse Transcriptase Orthopoxvirus Endogenous Metabolite
Adefovir dipivoxil, an adenosine analogue, is an oral proagent of the nucleoside reverse transcriptase inhibitor Adefovir. Adefovir dipivoxil inhibits both the wild type and HBV Lamivudine-resistant strains . Adefovir dipivoxil shows anti-orthopoxvirus activity.

HY-108776

(Rac)-sn-Glycerol 3-phosphate sodium DL-α-Glycerol phosphate sodium	Structural Classification Natural Products Human Gut Microbiota Metabolites Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite
(Rac)-sn-Glycerol 3-phosphate sodium is an a-site substrate analogue. (Rac)-sn-Glycerol 3-phosphate sodium is bound to the a-site, the rate of reaction of indole and nucleophilic indole analogues with E(A-A) is strongly inhibited .

HY-125453

Symplostatin 1	Structural Classification Natural Products Microorganisms Source classification	Others
Symplostatin 1 is a Dolastatin 10 (HY-15580) analogue that can be isolated from the marine cyanobacterium Symploca hydnoides .

HY-N8609

Uralsaponin C	Triterpenes Structural Classification Leguminosae Ketones, Aldehydes, Acids Terpenoids Source classification Plants Glycyrrhiza uralensis Fisch.	Others
Uralsaponin C is an analogue of oleanane-type triterpenoid saponin. Uralsaponin C can be isolated from the roots of Glycyrrhiza uralensis Fisch .

HY-125150

AL-3138 11-Deoxy-16-fluoro PGF2α	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Endocrinology	Prostaglandin Receptor Endogenous Metabolite
AL-3138 (11-Deoxy-16-fluoro PGF2α) is a prostaglandin F2 alpha (PGF2alpha) analogue that antagonises FP prostaglandin receptor-mediated inositol phosphate production .

HY-N7251

Stachartin A Stachybotrysin	Structural Classification Monophenols Microorganisms Source classification Phenols	Others
Stachartin A is a phenylspirodrimane-type analogue. Stachartin A can be isolated from the tin mine tailings-associated fungus Stachybotrys chartarum .

HY-N9340

Hypoglaunine D	Infection Alkaloids Classification of Application Fields Source classification Celastraceae Pyridine Alkaloids Plants Disease Research Fields Tripterygium hypoglaucum (Levl. ) Hutch.	HIV
Hypoglaunine D is an analogue of Triptonine B and acts as an anti-HIV compound. Hypoglaunine D inhibits HIV replication in H9 lymphocytes with an EC₅₀ value of 22 μg/ml .

HY-N9026

Stachartin B	Structural Classification Monophenols Microorganisms Source classification Phenols	Others
Stachartin B is a phenylspirodrimane-type analogue. Stachartin B can be isolated from the tin mine tailings-associated fungus Stachybotrys chartarum .

HY-N8773

3,5,7-Trihydroxychromone	other families Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Phenols Polyphenols Plants Disease Research Fields	Others
3,5,7-Trihydroxychromone is the analogue of galangin. 3,5,7-Trihydroxychromone is also the binder of bovine serum albumin. 3,5,7-Trihydroxychromone undergoes multiple antioxidant pathways .

HY-N2387R

Pinosylvin (Standard)	Structural Classification Stilbenes Polygonaceae Reynoutria japonica Houtt. Source classification Phenols Polyphenols Plants	Bacterial Apoptosis Autophagy
Pinosylvin (Standard) is the analytical standard of Pinosylvin. This product is intended for research and analytical applications. Pinosylvin is a pre-infectious stilbenoid toxin isolated from the heartwood of Pinus species, has anti-bacterial activities . Pinosylvin is a resveratrol analogue, can induce cell apoptosis and autophapy in leukemia cells .

HY-N8377

Capsiate 1 Publications Verification	Structural Classification Monophenols Capsicum annuum L. Classification of Application Fields Source classification Phenols Solanaceae Plants Inflammation/Immunology Disease Research Fields	TRP Channel
Capsiate, as a capsaicin analogue extracted from a non-pungent cultivar of CH-19 sweet red pepper, is an orally active agonist of TRPV1 .

HY-B0255R

Adefovir dipivoxil (Standard)	Structural Classification Natural Products Source classification Endogenous metabolite	HBV Reverse Transcriptase Orthopoxvirus Endogenous Metabolite
Adefovir dipivoxil (Standard) is the analytical standard of Adefovir dipivoxil. This product is intended for research and analytical applications. Adefovir dipivoxil, an adenosine analogue, is an oral proagent of the nucleoside reverse transcriptase inhibitor Adefovir. Adefovir dipivoxil inhibits both the wild type and HBV Lamivudine-resistant strains . Adefovir dipivoxil shows anti-orthopoxvirus activity.

HY-N8495

4'-Hydroxyflavanone	Flavonoids Monophenols Microorganisms Classification of Application Fields Flavonones Source classification Phenols Metabolic Disease Disease Research Fields	Others
4'-Hydroxyflavanone is an inhibitor of SREBP maturation and lipid synthesis. 4'-Hydroxyflavanone is a synthetic analogue of flavanone, has potential for hepatic steatosis and dyslipidemia research .

HY-163112

Anticancer agent 179	Structural Classification Monophenols Microorganisms Source classification Phenols	Others
Anticancer agent 179 (Compound 3) is a sambutoxin analogue. Anticancer agent 179 can impede migration of MDA-MB-231 breast cancer cells .

HY-N8377R

Capsiate (Standard)	Structural Classification Monophenols Capsicum annuum L. Source classification Phenols Solanaceae Plants	TRP Channel
Capsiate (Standard) is the analytical standard of Capsiate. This product is intended for research and analytical applications. Capsiate, as a capsaicin analogue extracted from a non-pungent cultivar of CH-19 sweet red pepper, is an orally active agonist of TRPV1 .

HY-N5102

D-(+)-Fucose	Ipomoea muricata Source classification Other Diseases Plants Convolvulaceae Disease Research Fields Saccharides	Others
D-(+)-Fucose is a nonmetabolizable analogue of l-arabinose. D-(+)-Fucose prevents growth of Escherichia coli B/r on a mineral salts medium plus l-arabinose by inhibiting induction of the l-arabinose operon . D-fucose is a potent inducer of beta-methylgalactoside permease (MGP) .

HY-N5102R

D-(+)-Fucose (Standard)	Ipomoea muricata Source classification Plants Convolvulaceae Saccharides	Others
D-(+)-Fucose (Standard) is the analytical standard of D-(+)-Fucose. This product is intended for research and analytical applications. D-(+)-Fucose is a nonmetabolizable analogue of l-arabinose. D-(+)-Fucose prevents growth of Escherichia coli B/r on a mineral salts medium plus l-arabinose by inhibiting induction of the l-arabinose operon . D-fucose is a potent inducer of beta-methylgalactoside permease (MGP) .

HY-N11921

*Kadsurin A analogue-1*	Structural Classification Source classification Lignans Piperaceae Phenylpropanoids Plants Piper kadsura (Choisy) Ohwi	Others
Kadsurin A analogue-1 (Compound 8) is a lignan can be extracted from Piper argyrophylum .

HY-U00082

Tigloidin Tigloyl pseudotropine; Tiglylpseudotropine; Tiglyssin	Alkaloids Classification of Application Fields Datura innoxia Miller Source classification Plants Solanaceae Disease Research Fields Inflammation/Immunology	Others
Tigloidin is an analogue of atropine, with anticholinergic activity.

HY-N6002

3'-Hydroxypterostilbene 1 Publications Verification	Structural Classification Stilbenes Classification of Application Fields Leguminosae Source classification Phenols Polyphenols Plants Disease Research Fields Cancer Sphaerophysa salsula	Apoptosis Autophagy
3'-Hydroxypterostilbene is a Pterostilbene (HY-N0828) analogue. 3'-Hydroxypterostilbene inhibits the growth of COLO 205, HCT-116 and HT-29 cells with IC₅₀s of 9.0, 40.2 and 70.9 µM, respectively. 3'-Hydroxypterostilbene significantly down-regulates PI3K/Akt and MAPKs signaling pathways and effectively inhibits the growth of human colon cancer cells by inducing apoptosis and autophagy. 3'-Hydroxypterostilbene can be used for the research of cancer .

HY-Y1373

Cyclohexanecarboxylic acid Hexahydrobenzoic acid	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Endogenous Metabolite
Cyclohexanecarboxylic acid is a Valproate structural analogue with anticonvulsant action .

HY-N7975

Lucidin 3-O-glucoside	Infection Quinones Monophenols other families Classification of Application Fields Anthraquinones Source classification Phenols Plants Disease Research Fields	Others
Lucidin 3-O-glucoside is an anthraquinone analogue .

HY-59132

2-Amino-1-phenylethanol	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
2-Amino-1-phenylethanol is an analogue of noradrenaline.

HY-N10353

4-Methyl withaferin A	Classification of Application Fields Source classification Withania somnifera Plants Solanaceae Disease Research Fields Inflammation/Immunology Steroids	Others
4-Methyl withaferin A is a withaferin A-analogue with anti-tumor activity .

HY-N12591

Iso-isariin B	Structural Classification Natural Products Microorganisms Source classification	Others
Iso-isariin B is an analogue of cyclocarboxyphenate, which can be used in antifungal studies .

HY-N11893

8-C-Glucosyl-(R)-aloesol (R)-Aloesinol	Structural Classification Natural Products Liliaceae Source classification Aloe vera (L.) Burm. f. Plants	Others
8-C-Glucosyl-(R)-aloesol ((R)-Aloesinol) is a bioactive chromone analogue .

HY-69014

2-O-Methylcytosine	Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Cancer	DNA/RNA Synthesis Endogenous Metabolite
2-O-Methylcytosine, an O-alkylated analogue a DNA adduct, is the damaged nucleobase .

HY-21754

Hygric acid N-Methyl-L-proline	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Rutaceae Plants Disease Research Fields Citrus reticulata Blanco	Others
Hygric acid (N-Methyl-L-proline) is a proline analogue found in the citrus juices and the juice of bergamot .

HY-N12519

1,2-Didehydrocryptotanshinone	Triterpenes Structural Classification Terpenoids Labiatae Source classification Samanea saman (Jacq.) Merr. Plants	Others
1,2-Didehydrocryptotanshinone is a structural analogue of cryptotanshinone (CT) (HY-N0174) .

HY-121305A

L-Ribulose	Infection Structural Classification Human Gut Microbiota Metabolites Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Saccharides Monosaccharides Cancer	Endogenous Metabolite
L-Ribulose, an isomer of L-ribose, is an important precursor for other rare sugars and L-nucleoside analogue synthesis .

HY-W007656

Cyclen	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Plants Menispermaceae Disease Research Fields Stephania japonica (Thunb.) Miers	Others
Cyclen is the aza analogue of crown ether, used as a precursor for MRI contrast agents, and is an intermediate for the preparation of effective macrocyclic chelates .

HY-126752

Ophthalmic acid	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Reactive Oxygen Species
Ophthalmic acid, an analogue of GSH, is a marker of oxidative stress and hepatic GSH consumption. Ophthalmic acid is an inhibitor of Glyoxalase I reaction .

HY-N0891

Tubeimoside II Tubeimoside-B	Triterpenes Structural Classification other families Classification of Application Fields Terpenoids Source classification Plants Disease Research Fields Cancer	Others
Tubeimoside II (Tubeimoside-B) is a natural analogue of oleanane type of triterpenoid saponin; show anti-inflammatory, antitumor, and antitumor-promoting effects.

HY-W008150

2-Hydroxy-3-methylbutanoic acid	Structural Classification Ketones, Aldehydes, Acids Source classification Disease markers Endocrine diseases Nervous System Disorder Endogenous metabolite	Endogenous Metabolite
2-Hydroxy-3-methylbutanoic acid is a close structure analogue of GHB, which is a naturally occurring neurotransmitter and a psychoactive agent.

HY-Y1373R

Cyclohexanecarboxylic acid (Standard)	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Endogenous Metabolite
Cyclohexanecarboxylic acid (Standard) is the analytical standard of Cyclohexanecarboxylic acid. This product is intended for research and analytical applications. Cyclohexanecarboxylic acid is a Valproate structural analogue with anticonvulsant action .

HY-13677

6-Mercaptopurine 5+ Cited Publications Mercaptopurine; 6-MP	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Cancer	Nucleoside Antimetabolite/Analog Autophagy Endogenous Metabolite
6-Mercaptopurine is a purine analogue which acts as an antagonist of the endogenous purines and has been widely used as antileukemic agent and immunosuppressive drug.

HY-W011688

Methyl palmitoleate 1 Publications Verification (Z)-Methyl hexadec-9-enoate; Methyl cis-9-Hexadecenoate	Structural Classification Natural Products other families Classification of Application Fields Source classification Other Diseases Plants Disease Research Fields	Others
Methyl palmitoleate ((Z)-Methyl hexadec-9-enoate), a fatty acid methyl ester, is an analogue of Palmitoleate with cytoprotective and growth-promoting properties .

HY-N1567

Pterolactam	Structural Classification Natural Products Vitex rotundifolia Source classification Plants Compositae	Fungal
Pterolactam can be isolated from Chrysanthemum coronarium L. Pterolactam derivates serval analogues that Mannich bases of amide with antifungal activities and cytotoxicity .

HY-121520

Docosahexaenoyl glycine	Cardiovascular Disease Structural Classification Alkaloids Classification of Application Fields Ketones, Aldehydes, Acids Other Alkaloids Source classification Endogenous metabolite Disease Research Fields	Potassium Channel Endogenous Metabolite
Docosahexaenoyl glycine is a PUFA analogue. Docosahexaenoyl glycine has activating effects on IKs?channels?and restore the function of IKs?channels with LQT1 mutation .

HY-W048510

Epiquinidine	Alkaloids Structural Classification other families Classification of Application Fields Source classification Other Diseases Quinoline Alkaloids Plants Disease Research Fields	Others
Epiquinidine, a quinine analogue, can be used as the ggTas2r1 agonist. Epiquinidine activates ggTas2r1 at or beyond 10 µM .

HY-N9454

Garcinoic acid	Monophenols other families Classification of Application Fields Ketones, Aldehydes, Acids Source classification Phenols Plants Disease Research Fields Cancer	Others
Garcinoic acid is the vitamin E analogue extracted from Garcinia Kola seeds. Garcinoic acid shows a marked antiproliferative effect on glioma C6 cancer cells .

HY-138146

4-Dehydrowithaferin A 4-oxo Withaferin A	Quinones Classification of Application Fields Source classification Benzene Quinones Withania somnifera Plants Solanaceae Disease Research Fields Cancer	Others
4-Dehydrowithaferin A is the analogue of withaferin A. Withaferin A is a withanolide isolated from Withania somnifera. 4-Dehydrowithaferin A has the potential for the research of multiple myeloma .

HY-N7288

Trilepisflavan	Structural Classification Monophenols Thymelaeaceae Source classification Daphne giraldii Nitsche Phenols Plants	Others
Trilepisflavan is a flavan, which can be isolated from Trilepisium madagascariense. Trilepisflavan derivates serval analogues with anti-cancer activity against human cancer cells .

HY-116117

Salicylcurcumin	Structural Classification Monophenols Animals Source classification Phenols	Others
Salicylcurcumin is a synthetic curcumin analogue with antioxidant activity. Salicylcurcumin may affect lipid peroxidation in fish, favoring increased survival, disease resistance, and ultimately growth rate .

Cat. No.	Product Name	Chemical Structure

HY-12522S

PF-06380101-d8 2 Publications Verification
PF-06380101-d₈ is a deuterium labeled PF-06380101. PF-06380101, an Auristatin microtubule inhibitor, is a cytotoxic Dolastatin 10 analogue[1].

HY-A0020S

Eldecalcitol-d6
Eldecalcitol-d₆ is the deuterium labeled Eldecalcitol. Eldecalcitol is an orally active analogue of active vitamin D used in the treatment of osteoporosis.

HY-Y1373S1

Cyclohexanecarboxylic acid-d11
Cyclohexanecarboxylic acid-d₁₁ is the deuterium labeled Cyclohexanecarboxylic acid[1]. Cyclohexanecarboxylic acid is a Valproate structural analogue with anticonvulsant action[2].

HY-B0577S

Latanoprost-d4
Latanoprost-d₄ is the deuterium labeled Latanoprost. Latanoprost (PHXA41) is a prostaglandin F2α analogue and an agonist for the FP prostanoid receptor, and lowers intraocular-pressure (IOP).

HY-A0273S

Propyphenazone-d3
Propyphenazone-d₃ is the deuterium labeled Propyphenazone. Propyphenazone is a pyrazolone derivative with anti-inflammatory, analgesic and antipyretic activity, Propyphenazone-based analogues as proagents and selective cyclooxygenase-2 inhibitors.

HY-B1342S5

Gildeuretinolum
Gildeuretinolum (Retinol-d3; Vitamin A1-d3) is a vitamin A analogue .

HY-Y1373S

Cyclohexanecarboxylic acid-d1
Cyclohexanecarboxylic acid-d₁ is the deuterium labeled Cyclohexanecarboxylic acid[1]. Cyclohexanecarboxylic acid is a Valproate structural analogue with anticonvulsant action[2].

HY-17426S

Famciclovir-d4
Famciclovir-d₄ is the deuterium labeled Famciclovir. Famciclovir (BRL 42810) is a guanine analogue antiviral agent used for the treatment of various herpesvirus infections[1][2].

HY-A0096S

Iloprost-d4
Iloprost-d₄ (Ciloprost-d4) is the deuterium labeled Iloprost. Iloprost (ZK 36374) is a synthetic analogue of prostacyclin PGI2[1][2].

HY-B0283S

Acipimox-d4
Acipimox-d4 is the deuterium labeled Acipimox. Acipimox (K-9321), a nicotinic acid analogue, is an antilipolytic compound. Acipimox acutely inhibits lipolysis and suppresses systemic levels of free fatty acids (FFAs) and improves insulin sensitivity .

HY-13677S

6-Mercaptopurine-d2
6-Mercaptopurine-d₂ is the deuterium labeled 6-Mercaptopurine. 6-Mercaptopurine is a purine analogue which acts as an antagonist of the endogenous purines and has been widely used as antileukemic agent and immunosuppressive agent[1][2].

HY-B0424S

Nitrendipine-d5
Nitrendipine-d₅ is the deuterium labeled Nitrendipine. Nitrendipine (BAY-E-5009), an analogue of Nifedipine (HY-B0284), is a dihydropyridine calcium channel blocker with vasodilator action. Nitrendipine has antihypertensive effect[1][2][3][4].

HY-B0077S1

Bendamustine-d8 hydrochloride
Bendamustine-d₈ (hydrochloride) is deuterium labeled Bendamustine (hydrochloride). Bendamustine hydrochloride (SDX-105), a purine analogue, is a DNA cross-linking agent. Bendamustine hydrochloride activats DNA-damage stress response and apoptosis. Bendamustine hydrochloride has potent alkylating, anticancer and antimetabolite properties[1].

HY-W008351S

L-Ribose-13C
L-Ribose- ¹³C is the ¹³C labeled L-Ribose. L-Ribose, a non-naturally occurring pentose, is an ideal starting material for use in synthesizing L-nucleosides analogues. Many anticancer and antiviral agents are synthesized based on a backbone of L-Ribose and i

HY-13677S1

6-Mercaptopurine-13C2,15N
6-Mercaptopurine- ¹³C₂, ¹⁵N is the ¹³C- and ¹⁵N-labeled 6-Mercaptopurine. 6-Mercaptopurine is a purine analogue which acts as an antagonist of the endogenous purines and has been widely used as antileukemic agent and immunosuppressive agent.

HY-13567S1

Bendamustine-d8
Bendamustine-d₈ is the deuterium labeled Bendamustine[1]. Bendamustine (SDX-105 free base), a purine analogue, is a DNA cross-linking agent. Bendamustine activates DNA-damage stress response and apoptosis. Bendamustine has potent alkylating, anticancer and antimetabolite properties[2].

HY-Y1129S

3-Hydroxypyridine-d4
3-Hydroxypyridine-d₄ is the deuterium labeled 3-Hydroxypyridine[1]. 3-Hydroxypyridine is isolated from Bamboo grass. 3-Hydroxypyridine derivatives are structural analogues of vitamin B6 and have a wide range of pharmacological properties, such as antioxidant properties[2][3].

HY-W714356

N-6-Methyl-2-deoxyadenosine-d3
N-6-Methyl-2-deoxyadenosine-d3 is the deuterium labeled N-6-Methyl-2-deoxyadenosine (HY-W011725). N-6-Methyl-2-deoxyadenosine is an adenine nucleoside analogue .

HY-N6786S

Ochratoxin B-13C20
Ochratoxin B- ¹³C₂₀ is ¹³C-labeled Ochratoxin B (HY-N6786). Ochratoxin B, a secondary metabolite of Aspergillus ochraceus, is the nonchlorinated analogue of the mycotoxin Ochratoxin A. Ochratoxin B has been shown to reduce the toxic effects of Ochratoxin A, and it is one of the most potent renal carcinogens in rodents .

HY-W718300

Indole-3-pyruvic acid-d5
Indole-3-pyruvic acid-d₅ is deuterated labeled Indole-3-pyruvic acid. Indole-3-pyruvic acid, a keto analogue of tryptophan, is an orally active AHR agonist. Indole-3-pyruvic acid has antioxidant properties, and can be used in the research of inflammation, anxiety .

HY-15583S

Auristatin F-d8
Auristatin F-d₈ is deuterium labeled Auristatin F (HY-15583). Auristatin F is a potent cytotoxin in antibo-conjugated agents and an analogue of MMAF. Auristatin F is a potent microtubule inhibitor and vascular damaging agent (VDA). Auristatin F inhibits cell division by preventing tubulin aggregation.Auristatin F can be used in antibody-drug conjugates (ADC) .

HY-113068S

β-Tocopherol-d3
β-Tocopherol-d₃ is the deuterium labeled β-Tocopherol. β-Tocopherol is an analogue of vitamin E, exhibits antioxidant properties. β-Tocopherol can inhibit tyrosinase activity and melanin synthesis. β-Tocopherol can also prevent the inhibition of cell growth and of PKC activity caused by d-alpha-tocopherol[1][2][3].

HY-104077S

Remdesivir-d5 2 Publications Verification
Remdesivir-d₅ is a deuterium labeled Remdesivir. Remdesivir (GS-5734) is a nucleoside analogue, with effective antiviral activity, with EC50s of 74 nM for SARS-CoV and MERS-CoV in HAE cells, and 30 nM for murine hepatitis virus in delayed brain tumor cells. Remdesivir is highly effective in the control of 2019-nCoV (COVID-19) infection in vitro[1][2].

HY-101981S

Uridine 5'-monophosphate-15N2
Uridine 5'-monophosphate-15N2 is the 15N labeled Uridine 5'-monophosphate[1]. Uridine 5'-monophosphate (5'- Uridylic acid), a monophosphate form of UTP, can be acquired either from a de novo pathway or degradation products of nucleotides and nucleic acids in vivo and is a major nucleotide analogue in mammalian milk[2].

HY-104077S1

Remdesivir-d4
Remdesivir-d₄ is deuterium labeled Remdesivir. Remdesivir (GS-5734), a nucleoside analogue with effective antiviral activity, has EC50s of 74 nM for SARS-CoV and MERS-CoV in HAE cells, and 30 nM for murine hepatitis virus in delayed brain tumor cells. Remdesivir is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro[1][2].

HY-121246S

Fluorofenidone-d3
Fluorofenidone-d₃ is deuterium labeled Fluorofenidone. Fluorofenidone (AKF-PD), an analogue of AMR69, shows equivalent antifibrotic activity, lower toxicity and longer half-life. Fluorofenidone (AKF-PD) attenuates the progression of renal interstitial fibrosis partly by suppressing NADPH oxidase and extracellular matrix (ECM) deposition via the PI3K/Akt signalling pathway[1][2].

HY-101981S4

Uridine 5'-monophosphate-13C9 dilithium
Uridine 5'-monophosphate- ¹³C₉ (5'-?Uridylic acid- ¹³C₉) dilithium is ¹³C-labeled Uridine 5'-monophosphate (HY-101981). Uridine 5'-monophosphate (5'-?Uridylic acid), a monophosphate form of UTP, can be acquired either from a de novo pathway or degradation products of nucleotides and nucleic acids in vivo and is a major nucleotide analogue in mammalian milk.

HY-101981S5

Uridine 5'-monophosphate-15N2 dilithium
Uridine 5'-monophosphate- ¹⁵N₂ (5'-?Uridylic acid- ¹⁵N₂) dilithium is ¹⁵N labeled Uridine 5'-monophosphate (HY-101981). Uridine 5'-monophosphate (5'-?Uridylic acid), a monophosphate form of UTP, can be acquired either from a de novo pathway or degradation products of nucleotides and nucleic acids in vivo and is a major nucleotide analogue in mammalian milk.

HY-101981S2

Uridine 5'-monophosphate-d11 dilithium
Uridine 5'-monophosphate-d₁₁ (5'-?Uridylic acid-d₁₁) dilithium is deuterium labeled Uridine 5'-monophosphate (HY-101981). Uridine 5'-monophosphate (5'-?Uridylic acid), a monophosphate form of UTP, can be acquired either from a de novo pathway or degradation products of nucleotides and nucleic acids in vivo and is a major nucleotide analogue in mammalian milk.

HY-90006S

5-Fluorouracil-d1
5-Fluorouracil-d is the deuterium labeled 5-Fluorouracil. 5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer[1][2]. 5-Fluorouracil also inhibits HIV[3].

HY-118189S

Misoprostol acid-d5

Misoprostol acid-d₅ is deuterium labeled Misoprostol acid. Misoprostol acid is an active metabolite of Misoprostol. Misoprostol is a synthetic analogue of prostaglandin E1 (PGE1), extensively absorbed, and undergoes rapid de-esterification to Misoprostol acid in the gastrointestinal tract after oral administration. Misoprostol can be used for non-steroidal anti-inflammatory drug-induced (NSAID) gastric ulcers[1]. Misoprostol is an oral agent used to induce labor[2].

HY-104077S2

Remdesivir impurity 9-d4
Remdesivir impurity 9-d₄ is deuterium labeled Remdesivir. Remdesivir (GS-5734), a nucleoside analogue with effective antiviral activity, has EC50s of 74 nM for SARS-CoV and MERS-CoV in HAE cells, and 30 nM for murine hepatitis virus in delayed brain tumor cells. Remdesivir is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro[1][2].

HY-90006S2

5-Fluorouracil-15N2
5-Fluorouracil- ¹⁵N₂ is the ¹⁵N-labeled 5-Fluorouracil. 5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer[1][2]. 5-Fluorouracil also inhibits HIV[3].

HY-B0683S

Limaprost-d3
Limaprost-d₃ (17α,20-dimethyl-δ2-PGE1-d3) is the deuterium labeled Limaprost. Limaprost (OP1206) is a PGE1 analogue and a potent and orally active vasodilator. Limaprost increases blood flow and inhibits platelet aggregation. Limaprost pain relief, has antianginal effects, and can be used for ischaemic symptoms research[1][2].

HY-90006S1

5-Fluorouracil-13C,15N2

5-Fluorouracil- ¹³C, ¹⁵N₂ is the ¹³C and ¹⁵N labeled 5-Fluorouracil[1]. 5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer[2][3]. 5-Fluorouracil also inhibits HIV[4].

HY-101981S3

Uridine 5'-monophosphate-13C9,15N2 dilithium

Uridine 5'-monophosphate- ¹³C₉, ¹⁵N₂ (5'-?Uridylic acid- ¹³C₉, ¹⁵N₂) dilithium is ¹³C and ¹⁵N-labeled Uridine 5'-monophosphate (HY-101981). Uridine 5'-monophosphate (5'-?Uridylic acid), a monophosphate form of UTP, can be acquired either from a de novo pathway or degradation products of nucleotides and nucleic acids in vivo and is a major nucleotide analogue in mammalian milk.

HY-40136S

cis-4-Hydroxy-L-proline-d3

cis-4-Hydroxy-L-proline-d₃ is the deuterium labeled cis-4-Hydroxy-L-proline. cis-4-Hydroxy-L-proline, a proline analogue, is an inhibitor of collagen production. cis-4-Hydroxy-L-proline could inhibit fibroblast growth by preventing the deposition of triple-helical collagen on the cell layer. cis-4-Hydroxy-L-proline also depresses the growth of primary N-nitrosomethylurea-induced rat mammary tumors[1][2][3][4].

HY-90006S3

5-Fluorouracil-13C4,15N2

5-Fluorouracil- ¹³C₄, ¹⁵N₂ is the ¹³C and ¹⁵N labeled 5-Fluorouracil[1]. 5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer[2][3]. 5-Fluorouracil also inhibits HIV[4].

HY-101981S1

Uridine 5'-monophosphate-15N2,d11 dilithium

Uridine 5'-monophosphate- ¹⁵N₂,d₁₁ (5'-?Uridylic acid- ¹⁵N₂,d₁₁) dilithium is deuterium and ¹⁵N labeled Uridine 5'-monophosphate (HY-101981). Uridine 5'-monophosphate (5'-?Uridylic acid), a monophosphate form of UTP, can be acquired either from a de novo pathway or degradation products of nucleotides and nucleic acids in vivo and is a major nucleotide analogue in mammalian milk.

HY-17422S1

Acyclovir-d4

Acyclovir-d₄ is the deuterium labeled Acyclovir. Acyclovir (Aciclovir) is a guanosine analogue and an orally active antiviral agent. Acyclovir inhibits HSV-1 (IC50 of 0.85 μM), HSV-2 (IC50 of 0.86 μM) and varicella-zoster virus. Acyclovir can be phosphorylated by viral thymidine kinase (TK), and Acyclovir triphosphate interferes with viral DNA polymerization through competitive inhibition with guanosine triphosphate and obligatory chain termination[1][2][3]. Acyclovir prevents bacterial infections during induction therapy for acute leukaemia[4].

HY-13637S

Ganciclovir-d5

Ganciclovir-d₅ is the deuterium labeled Ganciclovir. Ganciclovir (BW 759), a nucleoside analogue, is an orally active antiviral agent with activity against CMV. Ganciclovir also has activity in vitro against members of the herpes group and some other DNA viruses. Ganciclovir inhibits the in vitro replication of human herpes viruses (HSV 1 and 2, CMV) and adenovirus serotypes 1, 2, 4, 6, 8, 10, 19, 22 and 28. Ganciclovir has an IC50 of 5.2 μM for feline herpesvirus type-1 (FHV-1)[1][2][3].

Cat. No.	Product Name		Classification

HY-121805

DBCO-C6-acid		ADC Synthesis DBCO
DBCO-C6-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-C6-acid can be used in the synthesis of carmaphycin analogues . DBCO- C6- acid is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-134654

*MRTX849 analog* 24**		Alkynes
MRTX849 analog 24 is an alkyne-containing click probe analogue of KRAS G12C inhibitor MRTX849, which is used to research MRTX849 function .

HY-19314A

Azvudine hydrochloride 1 Publications Verification RO-0622 hydrochloride; FNC hydrochloride		Azide
Azvudine (RO-0622) hydrochloride is a potent nucleoside reverse transcriptase inhibitor (NRTI), with antiviral activity on HIV, HBV and HCV. Azvudine hydrochloride exerts highly potent inhibition on HIV-1 (EC₅₀s ranging from 0.03 to 6.92 nM) and HIV-2 (EC₅₀s ranging from 0.018 to 0.025 nM). Azvudine hydrochloride inhibits NRTI-resistant viral strains . Azvudine (hydrochloride) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-19314

Azvudine 1 Publications Verification RO-0622; FNC		Azide
Azvudine (RO-0622) is a potent nucleoside reverse transcriptase inhibitor (NRTI), with antiviral activity on HIV, HBV and HCV. Azvudine exerts highly potent inhibition on HIV-1 (EC₅₀s ranging from 0.03 to 6.92 nM) and HIV-2 (EC₅₀s ranging from 0.018 to 0.025 nM). Azvudine inhibits NRTI-resistant viral strains . Azvudine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-12516

Desogestrel 1 Publications Verification Org-2969		Alkynes
Desogestrel (Org-2969) is a third-generation progesterone analogue contained in many oral contraceptive preparations. Desogestrel is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-15286

Sodium 4-pentynoate		Alkynes
Sodium 4-pentynoate is a alkynylacetate analogue, can be metabolically incorporated onto cellular proteins through biosynthetic mechanisms for profiling of acetylated proteins in diverse cell types . Sodium 4-pentynoate is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-120832

Azt-pmap		Azide
Azt-pmap, a nucleoside analogue, is an aryl phosphate derivative of AZT. Azt-pmap shows anti-HIV activity . AZT is a nucleoside reverse transcriptase inhibitor (NRTI) for HIV infection . Azt-pmap is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-125600

LY219703		Azide
LY219703 is a photoactivatable analogue of the antitumor diarylsulfonylurea sulofenur. LY219703 are distributed mainly in membranes, particularly those of organelles such as mitochondria .

HY-16247

Apoptone HE3235		Alkynes
Apoptone, synthetic analogue of 3β-androstanediol, is an orally bioavailable anticancer agent. Apoptone is active in rodent models of prostate and breast cancer . Apoptone is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-128708

ACPK		Azide
ACPK is a pyrrolysine analogue bearing an azide residue. ACPK is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-W259668

Homopropargylglycine		Alkynes
Homopropargylglycine is a Methionine (HY-13694) analogue. Homopropargylglycine is incorporated at a suitable rate into newly synthesized proteins in a variety of systems, including mammalian cell culture. Homopropargylglycine can be used to identify old and new protein populations . Homopropargylglycine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-133870

Itaconate-alkyne 1 Publications Verification ITalk		Alkynes
Itaconate-alkyne (ITalk) is a specific bioorthogonal probe for quantitative and site-specific chemoproteomic profiling of Itaconation in living cells. Itaconate-alkyne, a functional analogue of Itaconate, exhibits comparable antiinflammatory effect with Itaconate and enables the labeling of bona fide targets of Itaconate . Itaconate-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-77652

*Nucleoside-Analog-2* 1 Publications Verification		Azide
Nucleoside-Analog-2 is a 4'-Azidocytidine analogue against Hepatitis C virus (HCV) replication. Nucleoside-Analog-2 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-139859

APN-PEG36-tetrazine		Tetrazine ADC Synthesis
APN-PEG36-tetrazine is an analogue of APN-PEG4-tetrazine. APN-PEG4-tetrazine is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . APN-PEG36-tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

HY-144585

AGD-0182		Azide
AGD-0182 is a microtubule disrupting agent. AGD-0182 is a synthetic analogue of the naturally occurring tubulin-binding molecule Dolastatin 10 . AGD-0182 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-152659

N1-Propargylpseudouridine		Alkynes
N1-Propargylpseudouridine (see GL102032) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . N1-Propargylpseudouridine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-130481

Propargyl-PEG4-acid		Alkynes PROTAC Synthesis
Propargyl-PEG4-acid is a PEG-based PROTAC linker can be used in the synthesis of BTK-IAP PROTACs Ibrutinib (HY-10997)-based PROTAC 2 and an analogue PROTAC 3. PROTAC 3 causes BTK degradation with a DC₅₀ of 200 nM in THP-1 cells . Propargyl-PEG4-acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-134976

Azido-FTY720		Azide
Azido-FTY720 is a photoactivatable analogue of FTY720. Azido-FTY720 is used for identifying binding sites between FTY720 and its receptors . Azido-FTY720 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-152562

N-Propargyladenosine		Alkynes
N-Propargyladenosine is an adenosine analogue. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. The popular products in this series are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) . N-Propargyladenosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-152523

5-(Azidomethyl) arauridine		Azide
5-(Azidomethyl) arauridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis . 5-(Azidomethyl) arauridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-10443

Balapiravir 3 Publications Verification Ro 4588161; R1626		Azide
Balapiravir (Ro 4588161; R1626) is an orally active proagent of a nucleoside analogue inhibitor of the RNA-dependent RNA polymerase (RdRp) of HCV (R1479; 4'-Azidocytidine). Balapiravir has anti-HCV activity . Balapiravir is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-10443A

Balapiravir hydrochloride Ro 4588161 hydrochloride; R1626 hydrochloride		Azide
Balapiravir hydrochloride (Ro 4588161 hydrochloride; R1626 hydrochloride) is an orally active proagent of a nucleoside analogue inhibitor of the RNA-dependent RNA polymerase (RdRp) of HCV (R1479; 4'-Azidocytidine). Balapiravir hydrochloride has anti-HCV activity . Balapiravir (hydrochloride) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-145934

UDP-GalNAz disodium UDP-N-azidoacetylgalactosamine disodium		Azide
UDP-GalNAz disodium (UDP-N-azidoacetylgalactosamine disodium) is the analogue of UDP-GalNAc. UDP-GalNAc is the donor substrate of many N-acetylgalactosaminyltransferases, enzymes which transfer GalNAc from the nucleotide sugar to a saccharide or peptide acceptor . UDP-GalNAz (disodium) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-77650

4'-C-Azidouridine 4'-Azidouridine		Azide
4'-C-azidouridine (4'-Azidouridine) is a uridine analogue. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents . 4'-C-Azidouridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-152744

2’-O-Propargyladenosine		Alkynes
2’-O-Propargyladenosine is an adenosine analogue. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. The popular products in this series are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) . 2’-O-Propargyladenosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-129084

Propargylcholine bromide		Alkynes
Propargylcholine bromide is a choline analogue containing terminal propargyl that can be incorporated into all classes of Choline-containing phospholipids such as phosphatidylcholine and sphingomyelin, labeling Choline-containing phospholipids. Propargylcholine bromide-labeled phospholipid molecules can be visualized in cells with high sensitivity and spatial resolution. Propargylcholine bromide can be used as a molecular tool to study the biochemical and metabolic processes of Choline-containing phospholipids in cells . Propargylcholine (bromide) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-133927

(2E,6E)-3,7-Dimethyltrideca-2,6-dien-12-yn-1-ol		Alkynes
(2E,6E)-3,7-Dimethyltrideca-2,6-dien-12-yn-1-ol is a isoprenoid analogue . (2E,6E)-3,7-Dimethyltrideca-2,6-dien-12-yn-1-ol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-152746

2-Amino-6-chloropurine-9-(2’-O-propargyl)riboside		Alkynes
2-Amino-6-chloropurine-9-(2’-O-propargyl)riboside is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 2-Amino-6-chloropurine-9-(2’-O-propargyl)riboside is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-10444

R-1479 3 Publications Verification 4'-Azidocytidine		Azide
R-1479 (4'-Azidocytidine), a nucleoside analogue, is a specific inhibitor of RNA-dependent RNA polymerase (RdRp) of HCV. R-1479 inhibits HCV replication in the HCV subgenomic replicon system (IC₅₀=1.28 μM) . R-1479 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-118411

5-Ethynyl-2'-deoxyuridine Maximum Cited Publications 15 Publications Verification		PROTAC Synthesis Alkynes
5-Ethynyl-2'-deoxyuridine (EdU), a thymidine analogue, is incorporated into cellular DNA during DNA replication and the subsequent reaction of EdU with a fluorescent azide in a “Click” reaction. EdU staining is a fast, sensitive and reproducible method to study cell proliferation . 5-Ethynyl-2'-deoxyuridine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs . 5-Ethynyl-2'-deoxyuridine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-131802

3'-Azido-3'-deoxyadenosine		Azide
3'-Azido-3'-deoxyadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 3'-Azido-3'-deoxyadenosine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-152728

3’-Azido-3’-deoxycytidine		Azide
3’-Azido-3’-deoxycytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 3’-Azido-3’-deoxycytidine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-152868

3’-O-(2-Azidoethyl)adenosine		Azide
3’-O-(2-Azidoethyl)adenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 3’-O-(2-Azidoethyl)adenosine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-152870

2’-O-(2-Azidoethyl)adenosine		Azide
2’-O-(2-Azidoethyl)adenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 2’-O-(2-Azidoethyl)adenosine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-152448

2’-Azido-2’-deoxycytidine		Azide
2’-Azido-2’-deoxycytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 2’-Azido-2’-deoxycytidine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-152720

3’-Azido-3’-deoxyuridine		Azide
3’-Azido-3’-deoxyuridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 3’-Azido-3’-deoxyuridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-152684

2′-O-2-Propyn-1-ylguanosine		Alkynes
2′-O-2-Propyn-1-ylguanosine is a guanosine analogue. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7) . 2′-O-2-Propyn-1-ylguanosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-152737

3’-Deoxy-3’-azido-isocytidine		Azide
3’-Deoxy-3’-azido-isocytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 3’-Deoxy-3’-azido-isocytidine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-152592

3’-Azido-3’-deoxy-beta-L-cytidine		Azide
3’-Azido-3’-deoxy-beta-L-cytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 3’-Azido-3’-deoxy-beta-L-cytidine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-152601

3’-Azido-3’-deoxy-beta-L-adenosine		Azide
3’-Azido-3’-deoxy-beta-L-adenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 3’-Azido-3’-deoxy-beta-L-adenosine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-152525

5-(Azidomethyl)-2’-O-(2-methoxyethyl)uridine		Azide
5-(Azidomethyl)-2’-O-(2-methoxyethyl)uridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis . 5-(Azidomethyl)-2’-O-(2-methoxyethyl)uridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-105268

AzddMeC CS-92		Azide
AzddMeC (CS-92) is an antiviral nucleoside analogue and a potent potent, selective and orally active HIV-1 reverse transcriptase and HIV-1 replication inhibitor. In HIV-1-infected human PBM cells and HIV-1-infected human macrophages, the EC₅₀ values of AzddMeC are 9 nM and 6 nM, respectively . AzddMeC is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-152315

3’-Azido-3’-deoxy-N6-methyladenosine		Azide
3’-Azido-3’-deoxy-N6-methyladenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 3’-Azido-3’-deoxy-N6-methyladenosine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-152353

3’-Azido-3’-deoxy-2-thiouridine		Azide
3’-Azido-3’-deoxy-2-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 3’-Azido-3’-deoxy-2-thiouridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-152708

3’-Azido-3’-deoxy-5-trifluoromethyluridine		Azide
3’-Azido-3’-deoxy-5-trifluoromethyluridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 3’-Azido-3’-deoxy-5-trifluoromethyluridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-152782

4’-Azido-2’-deoxy-2’-fluoro-beta-D-arabinouridine		Azide
4’-Azido-2’-deoxy-2’-fluoro-beta-D-arabinouridine is a uridine analogue. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents . 4’-Azido-2’-deoxy-2’-fluoro-beta-D-arabinouridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-152645

3’-Azido-3’-deoxy-5-methyluridine		Azide
3’-Azido-3’-deoxy-5-methyluridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 3’-Azido-3’-deoxy-5-methyluridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-152724

3’-Azido-3’-deoxy-5-iodouridine		Azide
3’-Azido-3’-deoxy-5-iodouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 3’-Azido-3’-deoxy-5-iodouridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-152688

3’-Azido-3’-deoxy-5-fluorouridine		Azide
3’-Azido-3’-deoxy-5-fluorouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 3’-Azido-3’-deoxy-5-fluorouridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-152713

3’-Azido-3’-deoxy-5-methoxyuridine		Azide
3’-Azido-3’-deoxy-5-methoxyuridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc . 3’-Azido-3’-deoxy-5-methoxyuridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

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