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2237

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9

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18

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24

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63

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1

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7

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156

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115

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78

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820

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-17520

    MTF-753

    Fungal Infection
    Penthiopyrad (MTF-753) is a chiral carboxamide antifungal agent with a broad spectrum of fungicidal activity. Penthiopyrad can be used for controlling foliar and soil-borne plants diseases on a broad range of agricultural crops and turfgrass .
    Penthiopyrad
  • HY-N2736

    Others Others
    3′,4′,7-Trihydroxyflavone is a flavonoid aglycon compound isolated from broad bean pods .
    3′,4′,7-Trihydroxyflavone
  • HY-N3139

    Bacterial Infection
    Ombuin, isolated from Zanthoxylum armatum, displays broad spectrum antibacterial effect with MIC ranges from 125 to 500 μg/mL .
    Ombuin
  • HY-103348

    Boc-Asp(OMe)-FMK

    Caspase Inflammation/Immunology
    Boc-Asp(OME)-Fluoromethyl Ketone is a broad range caspase inhibitor that inhibits Fas-mediated phagocytosis and oxidative rupture inhibition, but does not affect the chemotactic activity of IL-8 .
    Boc-Asp(OMe)-fluoromethyl ketone
  • HY-17520R

    Fungal Infection
    Penthiopyrad (Standard) is the analytical standard of Penthiopyrad. This product is intended for research and analytical applications. Penthiopyrad (MTF-753) is a chiral carboxamide antifungal agent with a broad spectrum of fungicidal activity. Penthiopyrad can be used for controlling foliar and soil-borne plants diseases on a broad range of agricultural crops and turfgrass .
    Penthiopyrad (Standard)
  • HY-126604

    Others Infection
    Pyranonigrin A is isolated and identified from Penicillium brocae MA-231. Pyranonigrin A shows potent activity against a broad spectrum of human-, aqua-, and plant-pathogens .
    Pyranonigrin A
  • HY-106959

    (8S)-8-Fluoroerythromycin A; P-0501A

    Antibiotic Bacterial Infection
    Flurithromycin ((8S)-8-Fluoroerythromycin A) is an orally active broad spectrum antibiotic. Flurithromycin can be used in the research of bacterial infections .
    Flurithromycin
  • HY-10824B

    PT523 ammonium

    Others Cancer
    Talotrexin ammonium is a nonpolyglutamatable antifolate. Talotrexin ammonium improves antitumor activity in a broad spectrum of cancer models by targeting DHFR to inhibit tumor growth .
    Talotrexin ammonium
  • HY-161135

    Bacterial Infection
    TBAJ-5307 is a broad spectrum anti-non-tuberculous mycobacteria inhibitor that can target the FO-domain of the engine and preventing rotation and proton-translocation. TBAJ-5307 inhibits non-tuberculous mycobacteria in vitro and in vivo .
    TBAJ-5307
  • HY-133704

    Bacterial Fungal Antibiotic Infection
    Pyrrolnitrin is an antibiotic isolated from Pseudomonas pyrrocinia. Pyrrolnitrin shows a broad spectrum of antibiotic activity against fungi, yeast and gram-positive bacteria .
    Pyrrolnitrin
  • HY-108402

    Penicillin-binding protein (PBP) Bacterial Antibiotic Infection
    Cefodizime is a third generation cephalosporin antibiotic with a broad spectrum of antibacterial activity. Cefodizime has no renal toxic effect, good tolerance and immune regulation activity, and has the potential for severe infections of the respiratory and urinary tracts .
    Cefodizime
  • HY-108402A

    Penicillin-binding protein (PBP) Bacterial Antibiotic Infection
    Cefodizime sodium is a third generation cephalosporin antibiotic with a broad spectrum of antibacterial activity. Cefodizime sodium has no renal toxic effect, good tolerance and immune regulation activity, and can be used for the research of severe infections of the respiratory and urinary tracts .
    Cefodizime sodium
  • HY-121969

    HIV Infection
    DDX3-IN-2 is an active DEADbox polypeptide 3 (DDX3) inhibitor with an IC50 value of 0.3 μM. DDX3-IN-2 shows a broad spectrum of antiviral activity. DDX3-IN-2 has the potential to overcome HIV resistance .
    DDX3-IN-2
  • HY-135751

    Antibiotic DNA/RNA Synthesis Infection Cancer
    Holomycin is a secondary metabolite of the dithiolopyrrolone class. Holomycin also is a broad spectrum antibiotic. Holomycin has antitumor activity and can act in vivo on RNA synthesis .
    Holomycin
  • HY-126462

    Others Infection
    Lantic acid is a triterpenoid compound possessing antimicrobial activity. Lantic acid exhibits inhibitory effects on a broad range of both Gram-positive and Gram-negative bacteria, with particular potency against Escherichia coli and Bacillus subtilis. Lantic acid is utilized in the research and development of antimicrobial agents .
    Lantic acid
  • HY-126662

    Bacterial Infection
    Netzahualcoyone is a triterpenoid compound isolated from the Celastraceae plant family. Netzahualcoyone exhibits broad-spectrum antibiotic activity against Gram-positive bacteria and yeasts, but is not active against Gram-negative bacteria. Netzahualcoyone can be utilized in the development of antibiotics and for studying antimicrobial mechanisms .
    Netzahualcoyone
  • HY-B0849

    Fungal Reactive Oxygen Species Apoptosis Bacterial Phosphatase Infection
    Azoxystrobin is an orally active, broad-spectrum β-methoxyacrylate fungicide. Azoxystrobin inhibits mitochondrial respiration by binding to the Qo site of the cytochrome bc1 complex and inhibiting electron transfer. Azoxystrobin induces the production of reactive oxygen species (ROS) and induces cell apoptosis .
    Azoxystrobin
  • HY-108402R

    Penicillin-binding protein (PBP) Bacterial Antibiotic Infection
    Cefodizime (Standard) is the analytical standard of Cefodizime. This product is intended for research and analytical applications. Cefodizime is a third generation cephalosporin antibiotic with a broad spectrum of antibacterial activity. Cefodizime has no renal toxic effect, good tolerance and immune regulation activity, and has the potential for severe infections of the respiratory and urinary tracts .
    Cefodizime (Standard)
  • HY-B1729

    Oxidative Phosphorylation Bacterial Infection
    Phenoxyethanol has a broad spectrum of antimicrobial activity against various gram-negative and gram-positive bacteria. Phenoxyethanol is an uncouple agent in oxidative phosphorylation from respiration and competitively inhibits malate dehydrogenase. Phenoxyethanol is used as a preservative in cosmetic, vaccine, and textile, et al .
    Phenoxyethanol
  • HY-P1222
    LL-37, human
    2 Publications Verification

    Bacterial Infection
    LL-37, human is a 37-residue, amphipathic, cathelicidin-derived antimicrobial peptide, which exhibits a broad spectrum of antimicrobial activity. LL-37, human could help protect the cornea from infection and modulates wound healing .
    LL-37, human
  • HY-B0013

    (-)-Ofloxacin lactate

    Bacterial DNA/RNA Synthesis Infection
    Lavofloxacin lactate ((-)-ofloxacin lactate) is a class of broad-spectrum antimicrobials that can kill or inhibit a variety of bacteria. Lavofloxacin lactate binds to DNA rotase and topoisomerase IV, resulting in blocked DNA replication and repair, thus inhibiting bacterial growth. Lavofloxacin lactate can be used to study resistance mechanisms in bacteria, including studying resistance genes and mutations .
    Lavofloxacin lactate
  • HY-P1222A
    LL-37, human TFA
    2 Publications Verification

    Bacterial Infection
    LL-37, human TFA is a 37-residue, amphipathic, cathelicidin-derived antimicrobial peptide, which exhibits a broad spectrum of antimicrobial activity. LL-37, human TFA could help protect the cornea from infection and modulates wound healing .
    LL-37, human TFA
  • HY-114220

    Fungal Infection
    T-2307, an arylamidine, has antifungal activities in vitro and in vivo. T-2307 exhibits broad-spectrum activity against clinically significant pathogens, including Candida species (MIC range, 0.00025 to 0.0078 μg/ml), Cryptococcus neoformans (MIC range, 0.0039 to 0.0625 μg/ml), and Aspergillus species (MIC range, 0.0156 to 4 μg/mL) .
    T-2307
  • HY-12653
    LDC4297
    5 Publications Verification

    CDK HIV HSV Infection
    LDC4297 is a selective inhibitor of CDK7 with an IC50 value of 0.13 nM. LDC4297 inhibits human cytomegalovirus (HCMV) replication with an EC50 value of 24.5 nM. LDC4297 shows broad antiviral activities to Herpesviridae, Adenoviridae, Poxviridae, Retroviridae and Orthomyxoviridae with EC50 value of 0.02-1.21 μM. LDC4297 can be used for the research of infection .
    LDC4297
  • HY-12653A
    LDC4297 hydrochloride
    5 Publications Verification

    CDK HIV HSV Infection
    LDC4297 hydrochloride is a selective inhibitor of CDK7 with an IC50 value of 0.13 nM. LDC4297 hydrochloride inhibits human cytomegalovirus (HCMV) replication with an EC50 value of 24.5 nM. LDC4297 hydrochloride shows broad antiviral activities to Herpesviridae, Adenoviridae, Poxviridae, Retroviridae and Orthomyxoviridae with EC50 values of 0.02-1.21 μM. LDC4297 hydrochloride can be used for the research of infection .
    LDC4297 hydrochloride
  • HY-101870B

    INCB053914 phosphate

    Pim Cancer
    Uzansertib (INCB053914) phosphate is an orally active, ATP-competitive pan-PIM kinase inhibitor with IC50s of 0.24 nM, 30 nM, 0.12 nM for PIM1, PIM2, PIM3, respectively. Uzansertib phosphate has broad anti-proliferative activity against a variety of hematologic tumor cell lines .
    Uzansertib phosphate
  • HY-101870

    INCB053914

    Pim Cancer
    Uzansertib (INCB053914) is an orally active, ATP-competitive pan-PIM kinase inhibitor with IC50s of 0.24 nM, 30 nM, 0.12 nM for PIM1, PIM2, PIM3, respectively. Uzansertib has broad anti-proliferative activity against a variety of hematologic tumor cell lines .
    Uzansertib
  • HY-W010649

    Antibiotic HSP Others Cancer
    Isoxazole possesses broad biological activities with low cytotoxicity (e.g. anti-microbial, antibacterial, antifungal, anti-viral, anti-cancer, anti-inflammatory, immunomodulatory, analgesic, antituberculous or anti-diabetic properties), which is a member of five-membered heterocycles for a agent scaffold. Isoxazole with reversed ring can be used as HSP90 inhibitor. Isoxazole has been explored as BET bromodomain inhibitor and tricyclic Isoxazole is a promising for selective multidrug resistance protein (MRP1) inhibitors. Isoxazole is promising for research of various inhibitors and diseases .
    Isoxazole
  • HY-P1222B
    LL-37, human acetate
    2 Publications Verification

    Bacterial Infection Inflammation/Immunology
    LL-37, human acetate is a 37-residue, amphipathic, cathelicidin-derived antimicrobial peptide, which exhibits a broad spectrum of antimicrobial activity. LL-37, human acetate could help protect the cornea from infection and modulates wound healing .
    LL-37, human acetate
  • HY-100781

    D-APB; D-2-Amino-4-phosphonobutyric acid

    iGluR Neurological Disease
    D-AP4 (D-APB; D-2-Amino-4-phosphonobutyric acid), a phosphono analogue of glutamate, is an NMDA broad spectrum excitatory amino acid receptor antagonist. D-AP4 also is an agonist for a quisqualate-sensitized AP6 site in hippocampus. D-AP4 inhibits AMPA receptor-stimulated 57Co 2+ influx in cultured cerebellar granule cells (IC50 ≥ 100 μM) .
    D-AP4
  • HY-12170
    Prinomastat
    2 Publications Verification

    AG3340; KB-R9896

    MMP Apoptosis Cancer
    Prinomastat (AG3340) is a broad spectrum, potent, orally active metalloproteinase (MMP) inhibitor with IC50s of 79, 6.3 and 5.0 nM for MMP-1, MMP-3 and MMP-9, respectively. Prinomastat inhibits MMP-2, MMP-3, MMP-13 and MMP-9 with Kis of 0.05 nM, 0.3 nM, 0.03 nM and 0.26 nM, respectively. Prinomastat crosses blood-brain barrier. Antitumor avtivity .
    Prinomastat
  • HY-12170A
    Prinomastat hydrochloride
    2 Publications Verification

    AG3340 hydrochloride; KB-R9896 hydrochloride

    MMP Apoptosis Cancer
    Prinomastat hydrochloride (AG3340 hydrochloride) is a broad spectrum, potent, orally active metalloproteinase (MMP) inhibitor with IC50s of 79, 6.3 and 5.0 nM for MMP-1, MMP-3 and MMP-9, respectively. Prinomastat hydrochloride inhibits MMP-2, MMP-3, MMP-13 and MMP-9 with Kis of 0.05 nM, 0.3 nM, 0.03 nM and 0.26 nM, respectively. Prinomastat hydrochloride can cross blood-brain barrier. Antitumor avtivity .
    Prinomastat hydrochloride
  • HY-B1923
    Piperacillin
    5+ Cited Publications

    Pipracil

    Bacterial Antibiotic Beta-lactamase Penicillin-binding protein (PBP) Infection Cancer
    Piperacillin is a semisynthetic broad-spectrum β-lactam antibiotic which exhibits potent bactericidal activity against Gram-negative bacteria as well as select Gram-positive strains through penicillin-binding proteins. Piperacillin is most commonly used in combination with the β-lactamase inhibitor Tazobactam .
    Piperacillin
  • HY-156498

    Ras ERK Raf Ribosomal S6 Kinase (RSK) AMPK Apoptosis PARP Cancer
    RMC-7977 is an orally active triple-complex RAS inhibitor that can simultaneously bind to cyclophilin A (CYPA) (Kd = 195 nM) and KRAS (G12V) (Kd = 292 μM). It exhibits broad-spectrum inhibitory activity against KRAS, NRAS, and HRAS proteins and their various wild-type and mutant variants. RMC-7977 induces apoptosis by inhibiting the phosphorylation of ERK, CRAF, and RSK, as well as increasing PARP cleavage. This leads to tumor regression, reduces resistance in KRAS G12C cancer models, and demonstrates good tolerability across various RAS cancer models .
    RMC-7977
  • HY-151374

    PKD Cancer
    3-IN-PP1 is a protein kinase D (PKD) inhibitor. 3-IN-PP1 has potent pan-PKD inhibitory activity for PKD1, PKD2 and PKD3 with IC50 values of 108, 94 and 108 nM, respectively. 3-IN-PP1 also is a broad spectrum anticancer agent and has inhibition of several tumor cells growth. 3-IN-PP1 can be used for the research of cancer .
    3-IN-PP1
  • HY-B1923R

    Bacterial Antibiotic Beta-lactamase Penicillin-binding protein (PBP) Infection Cancer
    Piperacillin (Standard) is the analytical standard of Piperacillin. This product is intended for research and analytical applications. Piperacillin is a semisynthetic broad-spectrum β-lactam antibiotic which exhibits potent bactericidal activity against Gram-negative bacteria as well as select Gram-positive strains through penicillin-binding proteins. Piperacillin is most commonly used in combination with the β-lactamase inhibitor Tazobactam .
    Piperacillin (Standard)
  • HY-B0847
    Propiconazole
    1 Publications Verification

    Fungal Reactive Oxygen Species Infection
    Propiconazole is an orally active N-substituted triazole used as a fungicide. Propiconazole is a mouse liver hepatotoxicant and a hepatocarcinogen that has adverse reproductive and developmental toxicities in experimental animals .
    Propiconazole
  • HY-B0847R

    Fungal Reactive Oxygen Species Infection
    Propiconazole (Standard) is the analytical standard of Propiconazole. This product is intended for research and analytical applications. Propiconazole is an orally active N-substituted triazole used as a fungicide. Propiconazole is a mouse liver hepatotoxicant and a hepatocarcinogen that has adverse reproductive and developmental toxicities in experimental animals .
    Propiconazole (Standard)
  • HY-14865C
    Omadacycline hydrochloride
    15+ Cited Publications

    PTK0796 hydrochloride; Amadacycline hydrochloride

    Bacterial Antibiotic Infection
    Omadacycline (PTK 0796) hydrochloride, a first-in-class orally active aminomethylcycline antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline hydrochloride acts through the inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline hydrochloride possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline hydrochloride can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections .
    Omadacycline hydrochloride
  • HY-14865
    Omadacycline
    15+ Cited Publications

    PTK 0796; Amadacycline

    Bacterial Antibiotic Infection
    Omadacycline (PTK 0796), a first-in-class orally active aminomethylcycline antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline acts through the inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections .
    Omadacycline
  • HY-14865A

    PTK 0796 mesylate; Amadacycline mesylate

    Bacterial Antibiotic Infection
    Omadacycline (PTK 0796) mesylate, a first-in-class orally active aminomethylcycline antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline mesylate acts through the inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline mesylate possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline mesylate can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections .
    Omadacycline mesylate
  • HY-14865B
    Omadacycline tosylate
    15+ Cited Publications

    PTK 0796 tosylate; Amadacycline tosylate

    Bacterial Antibiotic Infection
    Omadacycline (PTK 0796) tosylate, a first-in-class orally active aminomethylcycline antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline tosylate acts through the inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline tosylate possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline tosylate can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections .
    Omadacycline tosylate
  • HY-14865BR

    Bacterial Antibiotic Infection
    Omadacycline (tosylate) (Standard) is the analytical standard of Omadacycline (tosylate). This product is intended for research and analytical applications. Omadacycline (PTK 0796) tosylate, a first-in-class orally active aminomethylcycline antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline tosylate acts through the inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline tosylate possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline tosylate can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections .
    Omadacycline tosylate (Standard)
  • HY-14865R

    Bacterial Antibiotic Infection
    Omadacycline (Standard) is the analytical standard of Omadacycline. This product is intended for research and analytical applications. Omadacycline (PTK 0796), a first-in-class orally active aminomethylcycline antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline acts through the inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections .
    Omadacycline (Standard)
  • HY-136240

    Parasite Infection
    Tioxazafen is a disubstituted oxadiazole and a broad-spectrum seed treatment nematicide. Tioxazafen is designed to provide consistent broad-spectrum control of nematodes in corn, soy, and cotton .
    Tioxazafen
  • HY-101575

    Acetylkelfizina; Acetylsulfamethoxypyrazine; FI6073

    Bacterial Antibiotic Infection
    Acetylazide is a synthetic broad-spectrum bacteriostatic antibiotic.
    Acetylazide
  • HY-16980

    TP-434

    Beta-lactamase Bacterial Antibiotic Infection
    Eravacycline is a potent and broad-spectrum antibacterial agent.
    Eravacycline
  • HY-B1839

    Fungal Infection
    Fluazinam is a broad spectrum pyridinamine fungal inhibitor.
    Fluazinam
  • HY-122089

    Bacterial Infection
    Lapyrium is a broad-spectrum antimicrobial surfactant .
    Lapyrium
  • HY-129234

    Antibiotic Bacterial Fungal DNA/RNA Synthesis Cancer
    Mazethramycin is an antitumor antibiotic that exerts its antitumor effect by interfering with cellular DNA replication and RNA synthesis. Mazethramycin can be used in cancer research .
    Mazethramycin

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