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L-Ascorbic acid-<sup>13</sup>C-1

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2694

Inhibitors & Agonists

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1518

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Inhibitory Antibodies

Natural
Products

Recombinant Proteins

907

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Antibodies

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Targets Recommended: Amino acid Transporter Amino Acid Derivatives Amino acid decarboxylase Hydroxycarboxylic Acid Receptor (HCAR) Free Fatty Acid Receptor Fatty Acid Synthase (FASN) Apical Sodium-Dependent Bile Acid Transporter G protein-coupled Bile Acid Receptor 1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W014141

*5,6-O-Isopropylidene-L-ascorbic* acid** L-Ascorbic acid 5,6-acetonide	Biochemical Assay Reagents	Others
5,6-O-Isopropylidene-L-ascorbic acid (L-Ascorbic acid 5,6-acetonide) is an organic compound. 5,6-O-Isopropylidene-L-ascorbic acid is a derivative of L-Ascorbic acid (vitamin C). Ascorbic acid has antioxidant properties.

HY-B0166S1

L-Ascorbic acid-13C L-Ascorbate-<sup>13sup>C; Vitamin C-<sup>13sup>C	Isotope-Labeled Compounds Reactive Oxygen Species Calcium Channel Apoptosis Endogenous Metabolite	Neurological Disease Metabolic Disease Cancer
L-Ascorbic acid- ¹³C is the ¹³C-labeled L-Ascorbic acid. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor[1][2][3]. L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells[4].

HY-B0166R

L-Ascorbic acid (Standard)	Reactive Oxygen Species Calcium Channel Apoptosis Endogenous Metabolite	Neurological Disease Metabolic Disease Cancer
L-Ascorbic acid (Standard) is the analytical standard of L-Ascorbic acid. This product is intended for research and analytical applications. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Ca_v3.2 channels with an IC₅₀ of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor ^[1] . L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells .

HY-B0166S3

L-Ascorbic acid-13C-2 L-Ascorbate-<sup>13sup>C-2; Vitamin C-<sup>13sup>C-2	Apoptosis Calcium Channel Endogenous Metabolite Reactive Oxygen Species	Neurological Disease Metabolic Disease Cancer
L-Ascorbic acid- ¹³C-2 is the ¹³C labeled L-Ascorbic acid. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen

HY-B0166S

L-Ascorbic acid-13C6 L-Ascorbate-<sup>13sup>C₆; Vitamin C-<sup>13sup>C₆	Isotope-Labeled Compounds Reactive Oxygen Species Calcium Channel Apoptosis Endogenous Metabolite	Neurological Disease Metabolic Disease Cancer
L-Ascorbic acid- ¹³C₆ is the ¹³C-labeled L-Ascorbic acid. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor[1][2][3]. L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells[4].

HY-B0166S2

L-Ascorbic acid-13C-1 L-Ascorbate-<sup>13sup>C-1; Vitamin C-<sup>13sup>C-1	Apoptosis Calcium Channel Endogenous Metabolite Reactive Oxygen Species	Neurological Disease Metabolic Disease Cancer
L-Ascorbic acid- ¹³C-1 is the ¹³C labeled L-Ascorbic acid. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen

HY-B0166S4

L-Ascorbic acid-13C-3 L-Ascorbate-<sup>13sup>C-3; Vitamin C-<sup>13sup>C-3	Apoptosis Calcium Channel Endogenous Metabolite Reactive Oxygen Species	Neurological Disease Metabolic Disease Cancer
L-Ascorbic acid- ¹³C-3 is the ¹³C labeled L-Ascorbic acid. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen

HY-B0166S5

L-Ascorbic acid-13C-4 L-Ascorbate-<sup>13sup>C-4; Vitamin C-<sup>13sup>C-4	Isotope-Labeled Compounds Apoptosis Calcium Channel Endogenous Metabolite Reactive Oxygen Species	Neurological Disease Metabolic Disease Cancer
L-Ascorbic acid- ¹³C-4 is the ¹³C labeled L-Ascorbic acid. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collag

HY-B0166AR

L-Ascorbic acid (sodium salt) (Standard)	Calcium Channel Reactive Oxygen Species Apoptosis Endogenous Metabolite	Cancer
L-Ascorbic acid (sodium salt) (Standard) is the analytical standard of L-Ascorbic acid (sodium salt). This product is intended for research and analytical applications. L-Ascorbic acid sodium salt (Sodium ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid sodium salt selectively inhibits Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid sodium salt is also a collagen deposition enhancer and an elastogenesis inhibitor ^[1] .

HY-B0166GLR

L-Ascorbic acid (GMP Like) (Standard)	Reactive Oxygen Species Apoptosis Calcium Channel Endogenous Metabolite	Neurological Disease Metabolic Disease Cancer
L-Ascorbic acid (GMP Like) (Standard) is the analytical standard of L-Ascorbic acid (GMP Like). This product is intended for research and analytical applications. L-Ascorbic acid (GMP Like) is the GMP Like class L-Ascorbic acid (HY-B0166). L-Ascorbic acid (L-Ascorbate, Vitamin C), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor ^[1] . L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells .

HY-B0166CR

L-Ascorbic acid (calcium dihydrate) (Standard)	Biochemical Assay Reagents	Others Cancer
L-Ascorbic acid (calcium dihydrate) (Standard) is the analytical standard of L-Ascorbic acid (calcium dihydrate). This product is intended for research and analytical applications. L-Ascorbic acid (calcium dihydrate) (L-Ascorbate (calcium dihydrate); Vitamin C (calcium dihydrate)) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-B0166

L-Ascorbic acid Maximum Cited Publications 53 Publications Verification L-Ascorbate; Vitamin C	Reactive Oxygen Species Calcium Channel Apoptosis Endogenous Metabolite	Neurological Disease Metabolic Disease Cancer
L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Ca_v3.2 channels with an IC₅₀ of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor ^[1] . L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells .

HY-B0166S8

L-Ascorbic acid-13C6-1 L-Ascorbate-1; Vitamin C-<sup>13sup>C₆-1	Isotope-Labeled Compounds Endogenous Metabolite Reactive Oxygen Species Calcium Channel Apoptosis	Cancer
L-Ascorbic acid- ¹³C₆-1 (L-Ascorbate-1; Vitamin C- ¹³C₆-1) is a ¹³C labeled L-Ascorbic acid (HY-B0166) ^[1]. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Ca_v3.2 channels with an IC₅₀ of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor . L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells .

HY-B0166A

L-Ascorbic acid sodium salt Maximum Cited Publications 53 Publications Verification Sodium ascorbate; Sodium L-ascorbate; Vitamin C sodium salt	Reactive Oxygen Species Calcium Channel Apoptosis Endogenous Metabolite	Cancer
L-Ascorbic acid sodium salt (Sodium ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid sodium salt selectively inhibits Ca_v3.2 channels with an IC₅₀ of 6.5 μM. L-Ascorbic acid sodium salt is also a collagen deposition enhancer and an elastogenesis inhibitor ^[1] .

HY-103701B

L-Ascorbic acid 2-phosphate magnesium hydrate 2 Publications Verification 2-Phospho-L-Ascorbic acid magnesium hydrate	Phosphatase Reactive Oxygen Species Endogenous Metabolite	Metabolic Disease
L-ascorbic acid 2-phosphate (2-Phospho-L-ascorbic acid) magnesium hydrate is a long-acting vitamin C derivative that can stimulate collagen formation and expression. L-ascorbic acid 2-phosphate magnesium hydrate can be used as a culture medium supplement for the osteogenic differentiation of human adipose stem cells (hASCs). L-ascorbic acid 2-phosphate magnesium hydrate increases alkaline phosphatase (ALP) activity and expression of runx2A in hASCs during the osteogenic differentiation ^[1] .

HY-107837

L-Ascorbic acid 2-phosphate trisodium 2 Publications Verification 2-Phospho-L-Ascorbic acid trisodium	Phosphatase Reactive Oxygen Species Endogenous Metabolite	Metabolic Disease
L-Ascorbic acid 2-phosphate trisodium (2-Phospho-L-ascorbic acid trisodium) is a long-acting vitamin C derivative that can stimulate collagen formation and expression ^[1]. L-Ascorbic acid 2-phosphate trisodium (2-Phospho-L-ascorbic acid trisodium) can be used as a culture medium supplement for the osteogenic differentiation of human adipose stem cells (hASCs). L-Ascorbic acid 2-phosphate trisodium (2-Phospho-L-ascorbic acid trisodium) increases alkaline phosphatase (ALP) activity and expression of runx2A in hASCs during the osteogenic differentiation .

HY-103701A

L-Ascorbic acid 2-phosphate magnesium 2 Publications Verification 2-Phospho-L-Ascorbic acid magnesium	Phosphatase Reactive Oxygen Species Endogenous Metabolite	Metabolic Disease
L-Ascorbic acid 2-phosphate magnesium (2-Phospho-L-ascorbic acid magnesium) is a?long-acting?vitamin?C?derivative?that can stimulate collagen formation and expression ^[1]. L-Ascorbic acid 2-phosphate magnesium (2-Phospho-L-ascorbic acid magnesium) can be used as a culture medium supplement for the osteogenic differentiation of human adipose stem cells (hASCs). L-Ascorbic acid 2-phosphate magnesium (2-Phospho-L-ascorbic acid magnesium) increases alkaline phosphatase (ALP) activity and expression of runx2A in hASCs during the osteogenic differentiation .

HY-B0166G

L-Ascorbic acid L-Ascorbate; Vitamin C	Reactive Oxygen Species Calcium Channel Apoptosis Endogenous Metabolite	Neurological Disease Metabolic Disease Cancer
L-Ascorbic acid (L-Ascorbate) (GMP) is L-Ascorbic acid (HY-B0166) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. L-Ascorbic acid is an inhibitor of Ca_v 3.2 channels ^[1].

HY-B0166GL

L-Ascorbic acid (GMP Like) L-Ascorbate (GMP Like); Vitamin C (GMP Like)	Reactive Oxygen Species Apoptosis Calcium Channel Endogenous Metabolite	Neurological Disease Metabolic Disease Cancer
L-Ascorbic acid (GMP Like) is the GMP Like class L-Ascorbic acid (HY-B0166). L-Ascorbic acid (L-Ascorbate, Vitamin C), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Ca_v3.2 channels with an IC₅₀ of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor ^[1] . L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells .

HY-16661

Skp2 Inhibitor C1 5+ Cited Publications SKPin C1	E1/E2/E3 Enzyme	Cancer
Skp2 Inhibitor C1 (SKPin C1) is an S-phase kinase-related protein 2 (Skp2) inhibitor with an inhibitory effect on metastatic melanoma cells. Skp2 Inhibitor C1 slows the cell cycle, inhibits cell proliferation, and triggers apoptosis ^[1].

HY-B0166S6

L-Ascorbic acid-d2 L-Ascorbate-d₂; Vitamin C--d₂	Apoptosis Calcium Channel Endogenous Metabolite Reactive Oxygen Species	Neurological Disease Metabolic Disease Cancer
L-Ascorbic acid-d₂ is the deuterium labeled L-Ascorbic acid. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a colla

HY-130173

Bafilomycin C1 1 Publications Verification	Bacterial Fungal Na+/K+ ATPase Apoptosis Antibiotic	Infection Cancer
Bafilomycin C1 is a macrolide antibiotic isolated from Streptomyces sp. Bafilomycin C1 is a potent, specific and reversible inhibitor of vacuolar-type H ⁺-ATPases (V-ATPases). Bafilomycin C1 inhibits growth of gram-positive bacteria and fungi . Bafilomycin C1 induces cell apoptosis and can be used for the study of hepatocellular carcinoma (HCC) .

HY-W588250

Surfactin C1	Integrin	Inflammation/Immunology
Surfactin C1 is an amphiphilic biosurfactants. Surfactin C1 inhibits leukemic cell (HL-60) adhesion to human umbilical vein endothelial cells (HUVEC). Surfactin C1 inhibits adhesion melecules expression, such as ICAM-1 and VCAM-1 ^[1].

HY-N12298

Ciwujianoside C1	Lipase	Others
Ciwujianoside C1 is a saponin, that can be isolated from the leaves of Acanthopanax senticosus. Ciwujianoside C1 inhibits pancreatic lipase activity in vitro ^[1].

HY-103701

L-Ascorbic acid 2-phosphate 2 Publications Verification 2-Phospho-L-Ascorbic acid	Phosphatase Reactive Oxygen Species Endogenous Metabolite	Metabolic Disease
L-ascorbic acid 2-phosphate (2-Phospho-L-ascorbic acid) is a long-acting vitamin C derivative that can stimulate collagen formation and expression ^[1]. L-ascorbic acid 2-phosphate (2-Phospho-L-ascorbic acid) can be used as a culture medium supplement for the osteogenic differentiation of human adipose stem cells (hASCs). L-ascorbic acid 2-phosphate increases alkaline phosphatase (ALP) activity and expression of runx2A in hASCs during the osteogenic differentiation .

HY-N2342R

Procyanidin C1 (Standard)	Apoptosis	Cancer
Procyanidin C1 (Standard) is the analytical standard of Procyanidin C1. This product is intended for research and analytical applications. Procyanidin C1 (PCC1), a natural polyphenol with oral activity, causes DNA damage, cell cycle arrest and induces apoptosis. Procyanidin C1 decreases the level of Bcl-2, but enhances BAX, caspase 3 and 9 expression in cancer cells. Procyanidin C1 shows senotherapeutic activity and increases lifespan in mice ^[1] .

HY-158925

Conglobatin C1	Endogenous Metabolite	Cancer
Conglobatin C1 is a bacterial metabolite and has anticancer activity. Conglobatin C1 is cytotoxic to NS-1 mouse myeloma cells (IC₅₀ = 1.05 μg/mL) .

HY-B0166C

L-Ascorbic acid calcium dihydrate L-Ascorbate calcium dihydrate; Vitamin C calcium dihydrate	Reactive Oxygen Species Calcium Channel Apoptosis Endogenous Metabolite	Others Cancer
L-Ascorbic acid (calcium dihydrate) (L-Ascorbate (calcium dihydrate); Vitamin C (calcium dihydrate)) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-N7234

Sarasinoside C1	Others	Others
Sarasinoside C1 is a 30-norlanostane saponin isolated from the sea sponge Melophlus sarasinorum collected from Kimbe Bay, Papua New Guinea. Sarasinoside C1 has potential roles in marine ecology and pharmacological applications ^[1].

HY-110246

Quin C1	Formyl Peptide Receptor (FPR)	Inflammation/Immunology
Quin C1 is a highly specific and potent agonist for formyl peptide receptor 2 (FPR2/ALX). Quin-C1 significantly reduces the neutrophil and lymphocyte counts in BALF, diminishes expression of TNF-α, IL-1β, KC, and TGF-β1, and decreases collagen deposition in lung tissue. Quin C1 has the potential for the research of lung injury ^[1].

HY-107837R

L-Ascorbic acid 2-phosphate (trisodium) (Standard)	Phosphatase Reactive Oxygen Species Endogenous Metabolite	Metabolic Disease

HY-N13149

Tetromycin C1	Antibiotic Bacterial	Infection
Tetromycin C1 is an antibiotic bactericide isolated from Streptomyces sp. ^[1].

HY-D1518

NerveGreen C1	Fluorescent Dye	Others
NerveGreen C1 is a fluorescent dye (Ex=500 nm, Em=615 nm).

HY-119219

Detoxin C1	Bacterial	Infection
Detoxin C1 is an active principle of detoxin complex. Detoxin complex is an antagonist of Blasticidin S ^[1].

HY-N12926

Cistantubuloside C1	Others	Others
Cistantubuloside C1 is a Phenylpropanoids product that can be isolated from the herbs of Cistanche deserticola Ma ^[1].

HY-123751

Antifolate C1 AGF 94	Antifolate	Cancer
Antifolate C1 (AGF 94) is a GARFTase inhibitor. Antifolate C1 inhibits de novo purine biosynthesis. Antifolate C1 inhibits cell proliferation ^[1].

HY-171025

Cannabiorcol Cannabinol C1; CBN-C1	Cannabinoid Receptor	Neurological Disease
Cannabiorcol (Cannabinol C1) is structurally similar to known phytocannabinoids.

HY-N2342

Procyanidin C1 4 Publications Verification PCC1	Apoptosis	Cancer
Procyanidin C1 (PCC1), a natural polyphenol with oral activity, causes DNA damage, cell cycle arrest and induces apoptosis. Procyanidin C1 decreases the level of Bcl-2, but enhances BAX, caspase 3 and 9 expression in cancer cells. Procyanidin C1 shows senotherapeutic activity and increases lifespan in mice ^[1] .

HY-N9898

Sinocrassoside C1	Others	Others
Sinocrassoside C1 is a natural compound isolated from themethanolic extract of the whole plant ofSinocrassula indica (Crassulaceae) ^[1].

HY-129151

Ganoderic acid C1	TNF Receptor	Inflammation/Immunology
Ganoderic acid C1, a natural compound that could be isolated from G. lucidum, suppresses TNF-α production by murine macrophages (RAW 264.7 cells) ^[1].

HY-B0987

Ascorbyl palmitate 3 Publications Verification L-Ascorbic acid 6-hexadecanoate; 6-O-Palmitoyl-L-Ascorbic acid	Reactive Oxygen Species Endogenous Metabolite Calcium Channel Sodium Channel Apoptosis NOD-like Receptor (NLR) Bcl-2 Family Caspase	Inflammation/Immunology
Ascorbyl palmitate is an orally active ester formed from ascorbic acid and palmitic acid, used as an antioxidant and food additive. Ascorbyl palmitate in preventing fat and oil oxidation is more efficient than Butylated hydroxyanisole (HY-B1066) and Butylated hydroxytoluene (HY-Y0172). Ascorbyl palmitate mitigates inhibition of collagen synthesis by select calcium and sodium channel blockers. Ascorbyl palmitate induces Apoptosis in human umbilical vein endothelial cells (HUVECs). Ascorbyl palmitate ameliorates inflammatory diseases by inhibition of NLRP3 inflammasome ^[1] .

HY-E70390

C1s Enzyme masp-2, c1 esterase, c1-esterase	Wnt	Cardiovascular Disease Inflammation/Immunology
C1s Enzyme is a subunit of the complement C1 complex, which activates the complement as a serine protease. C1s Enzyme cleaves LRP5 and LRP6, and thus activates the Wnt/β-Catenin signaling pathway. C1s Enzyme promotes the macrophage M2 polarization and inhibits M1 polarization. C1s Enzyme enhances efferocytosis, exhibits anti-inflammatory activity ^[1].

HY-W127734

L-Ascorbic acid, 2,6-dibutanoate 2,6-Di-O-butyryl-L-Ascorbic acid	Biochemical Assay Reagents	Others
L-Ascorbyl 2,6-Dibutyrate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-Y0418S1

Dulcite-13C-1 Dulcitol-<sup>13sup>C-1; Melampyrit-<sup>13sup>C-1; NSC 1944-<sup>13sup>C-1	Isotope-Labeled Compounds Endogenous Metabolite	Others
Dulcite- ¹³C-1 is the ¹³C labeled Dulcite. Dulcite is a sugar alcohol with a slightly sweet taste which is a metabolic breakdown product of galact[1][2].

HY-B0987R

Ascorbyl palmitate (Standard) L-Ascorbic acid 6-hexadecanoate (Standard); 6-O-Palmitoyl-L-Ascorbic acid (Standard)	Reactive Oxygen Species Endogenous Metabolite	Cancer
Ascorbyl palmitate (Standard) is the analytical standard of Ascorbyl palmitate. This product is intended for research and analytical applications. Ascorbyl palmitate is an ester formed from ascorbic acid and palmitic acid creating an vitamin C, it is also used as an antioxidant food additive.

HY-N1480S1

(-)-Fucose-13C-1 6-Desoxygalactose-<sup>13sup>C-1; L-(-)-Fucose-<sup>13sup>C-1; L-Galactomethylose-<sup>13sup>C-1	Isotope-Labeled Compounds Endogenous Metabolite Parasite	Infection Metabolic Disease
(-)-Fucose- ¹³C-1 is the ¹³C labeled (-)-Fucose. (-)-Fucose is classified as a member of the hexoses, plays a role in A and B blood group antigen substructure determination, selectin-mediated leukocyte-endothelial adhesion, and host-microbe interacti[

HY-B0389S11

D-Glucose-13C-1 Glucose-<sup>13sup>C-1; D-(+)-Glucose-<sup>13sup>C-1; Dextrose-<sup>13sup>C-1	Endogenous Metabolite	Metabolic Disease
D-Glucose- ¹³C-1 is the ¹³C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].

HY-158471

Core 1 O-glycan (C1)	Biochemical Assay Reagents	Others
Core 1 O-glycan (C1) is an important O-linked glycan with core structure 1 (MUC1-M). Core 1 O-glycan (C1), 2AB labeled is related to sialylation and participates in life activities including cell recognition, protection, immune regulation and disease markers ^[1].

HY-I0400S1

N-Acetylneuraminic acid-13C-1 NANA-<sup>13sup>C-1; Lactaminic acid-<sup>13sup>C-1	Isotope-Labeled Compounds Endogenous Metabolite Influenza Virus	Cardiovascular Disease
N-Acetylneuraminic acid- ¹³C-1 is the ¹³C labeled N-Acetylneuraminic acid.

HY-N1150S3

Thymidine-13C-1 DThyd-<sup>13sup>C-1; NSC 21548-<sup>13sup>C-1	Isotope-Labeled Compounds DNA/RNA Synthesis Endogenous Metabolite Orthopoxvirus	Cancer
Thymidine- ¹³C-1 is the ¹³C labeled Thymidine. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication[1]

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B0166R

L-Ascorbic acid (Standard)	Structural Classification Natural Products Microorganisms Moringa oleifera Lam. Source classification Disease markers Endocrine diseases Moringaceae Nervous System Disorder Plants Endogenous metabolite	Reactive Oxygen Species Calcium Channel Apoptosis Endogenous Metabolite
L-Ascorbic acid (Standard) is the analytical standard of L-Ascorbic acid. This product is intended for research and analytical applications. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Ca_v3.2 channels with an IC₅₀ of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor ^[1] . L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells .

HY-B0166

L-Ascorbic acid Maximum Cited Publications 53 Publications Verification L-Ascorbate; Vitamin C	Structural Classification Natural Products Neurological Disease Classification of Application Fields Moringa oleifera Lam. Source classification Endocrine diseases Metabolic Disease Plants Endogenous metabolite Microorganisms Disease markers Moringaceae Nervous System Disorder Disease Research Fields	Reactive Oxygen Species Calcium Channel Apoptosis Endogenous Metabolite
L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Ca_v3.2 channels with an IC₅₀ of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor ^[1] . L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells .

HY-B0166A

L-Ascorbic acid sodium salt Maximum Cited Publications 53 Publications Verification Sodium ascorbate; Sodium L-ascorbate; Vitamin C sodium salt	Structural Classification Natural Products other families Classification of Application Fields Source classification Plants Disease Research Fields Cancer	Reactive Oxygen Species Calcium Channel Apoptosis Endogenous Metabolite
L-Ascorbic acid sodium salt (Sodium ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid sodium salt selectively inhibits Ca_v3.2 channels with an IC₅₀ of 6.5 μM. L-Ascorbic acid sodium salt is also a collagen deposition enhancer and an elastogenesis inhibitor ^[1] .

HY-103701B

L-Ascorbic acid 2-phosphate magnesium hydrate 2 Publications Verification 2-Phospho-L-Ascorbic acid magnesium hydrate	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Phosphatase Reactive Oxygen Species Endogenous Metabolite
L-ascorbic acid 2-phosphate (2-Phospho-L-ascorbic acid) magnesium hydrate is a long-acting vitamin C derivative that can stimulate collagen formation and expression. L-ascorbic acid 2-phosphate magnesium hydrate can be used as a culture medium supplement for the osteogenic differentiation of human adipose stem cells (hASCs). L-ascorbic acid 2-phosphate magnesium hydrate increases alkaline phosphatase (ALP) activity and expression of runx2A in hASCs during the osteogenic differentiation ^[1] .

HY-107837

L-Ascorbic acid 2-phosphate trisodium 2 Publications Verification 2-Phospho-L-Ascorbic acid trisodium	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Phosphatase Reactive Oxygen Species Endogenous Metabolite
L-Ascorbic acid 2-phosphate trisodium (2-Phospho-L-ascorbic acid trisodium) is a long-acting vitamin C derivative that can stimulate collagen formation and expression ^[1]. L-Ascorbic acid 2-phosphate trisodium (2-Phospho-L-ascorbic acid trisodium) can be used as a culture medium supplement for the osteogenic differentiation of human adipose stem cells (hASCs). L-Ascorbic acid 2-phosphate trisodium (2-Phospho-L-ascorbic acid trisodium) increases alkaline phosphatase (ALP) activity and expression of runx2A in hASCs during the osteogenic differentiation .

HY-103701A

L-Ascorbic acid 2-phosphate magnesium 2 Publications Verification 2-Phospho-L-Ascorbic acid magnesium	Structural Classification Natural Products Human Gut Microbiota Metabolites Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Phosphatase Reactive Oxygen Species Endogenous Metabolite
L-Ascorbic acid 2-phosphate magnesium (2-Phospho-L-ascorbic acid magnesium) is a?long-acting?vitamin?C?derivative?that can stimulate collagen formation and expression ^[1]. L-Ascorbic acid 2-phosphate magnesium (2-Phospho-L-ascorbic acid magnesium) can be used as a culture medium supplement for the osteogenic differentiation of human adipose stem cells (hASCs). L-Ascorbic acid 2-phosphate magnesium (2-Phospho-L-ascorbic acid magnesium) increases alkaline phosphatase (ALP) activity and expression of runx2A in hASCs during the osteogenic differentiation .

HY-130173

Bafilomycin C1 1 Publications Verification	Infection Structural Classification Microorganisms Macrolide Antibiotics Antibiotics Source classification Antibacterial Disease Research Anticancer Disease Research Fields Cancer	Bacterial Fungal Na+/K+ ATPase Apoptosis Antibiotic
Bafilomycin C1 is a macrolide antibiotic isolated from Streptomyces sp. Bafilomycin C1 is a potent, specific and reversible inhibitor of vacuolar-type H ⁺-ATPases (V-ATPases). Bafilomycin C1 inhibits growth of gram-positive bacteria and fungi . Bafilomycin C1 induces cell apoptosis and can be used for the study of hepatocellular carcinoma (HCC) .

HY-103701

L-Ascorbic acid 2-phosphate 2 Publications Verification 2-Phospho-L-Ascorbic acid	Structural Classification Natural Products Human Gut Microbiota Metabolites Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Phosphatase Reactive Oxygen Species Endogenous Metabolite
L-ascorbic acid 2-phosphate (2-Phospho-L-ascorbic acid) is a long-acting vitamin C derivative that can stimulate collagen formation and expression ^[1]. L-ascorbic acid 2-phosphate (2-Phospho-L-ascorbic acid) can be used as a culture medium supplement for the osteogenic differentiation of human adipose stem cells (hASCs). L-ascorbic acid 2-phosphate increases alkaline phosphatase (ALP) activity and expression of runx2A in hASCs during the osteogenic differentiation .

HY-B0166AR

L-Ascorbic acid (sodium salt) (Standard)	Structural Classification Natural Products other families Source classification Plants	Calcium Channel Reactive Oxygen Species Apoptosis Endogenous Metabolite
L-Ascorbic acid (sodium salt) (Standard) is the analytical standard of L-Ascorbic acid (sodium salt). This product is intended for research and analytical applications. L-Ascorbic acid sodium salt (Sodium ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid sodium salt selectively inhibits Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid sodium salt is also a collagen deposition enhancer and an elastogenesis inhibitor ^[1] .

HY-N12298

Ciwujianoside C1	Triterpenes Structural Classification Polysaccharides Terpenoids Source classification Acanthopanax senticosus (Rupr. et Maxim.) Harms Plants Saccharides Araliaceae	Lipase
Ciwujianoside C1 is a saponin, that can be isolated from the leaves of Acanthopanax senticosus. Ciwujianoside C1 inhibits pancreatic lipase activity in vitro ^[1].

HY-N2342R

Procyanidin C1 (Standard)	Structural Classification Flavonoids Source classification Rosaceae Phenols Polyphenols Crataegus pinnatifida Bge. Plants Biflavones	Apoptosis
Procyanidin C1 (Standard) is the analytical standard of Procyanidin C1. This product is intended for research and analytical applications. Procyanidin C1 (PCC1), a natural polyphenol with oral activity, causes DNA damage, cell cycle arrest and induces apoptosis. Procyanidin C1 decreases the level of Bcl-2, but enhances BAX, caspase 3 and 9 expression in cancer cells. Procyanidin C1 shows senotherapeutic activity and increases lifespan in mice ^[1] .

HY-158925

Conglobatin C1	Structural Classification Microorganisms Macrolide Antibiotics Antibiotics Source classification	Endogenous Metabolite
Conglobatin C1 is a bacterial metabolite and has anticancer activity. Conglobatin C1 is cytotoxic to NS-1 mouse myeloma cells (IC₅₀ = 1.05 μg/mL) .

HY-107837R

L-Ascorbic acid 2-phosphate (trisodium) (Standard)	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Phosphatase Reactive Oxygen Species Endogenous Metabolite

HY-N13149

Tetromycin C1	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Antibiotic Bacterial
Tetromycin C1 is an antibiotic bactericide isolated from Streptomyces sp. ^[1].

HY-119219

Detoxin C1	Structural Classification Natural Products Microorganisms Source classification	Bacterial
Detoxin C1 is an active principle of detoxin complex. Detoxin complex is an antagonist of Blasticidin S ^[1].

HY-N12926

Cistantubuloside C1	Structural Classification Cistanche deserticola Ma Source classification Other Phenylpropanoids Orobanchaceae Phenylpropanoids Plants	Others
Cistantubuloside C1 is a Phenylpropanoids product that can be isolated from the herbs of Cistanche deserticola Ma ^[1].

HY-N2342

Procyanidin C1 4 Publications Verification PCC1	Structural Classification Classification of Application Fields Source classification Rosaceae Crataegus pinnatifida Bge. Plants Flavonoids Functional Molecules Research of Health Products Phenols Polyphenols Biflavones Disease Research Fields Cancer	Apoptosis
Procyanidin C1 (PCC1), a natural polyphenol with oral activity, causes DNA damage, cell cycle arrest and induces apoptosis. Procyanidin C1 decreases the level of Bcl-2, but enhances BAX, caspase 3 and 9 expression in cancer cells. Procyanidin C1 shows senotherapeutic activity and increases lifespan in mice ^[1] .

HY-N9898

Sinocrassoside C1	Structural Classification Sinocrassula indica (Decne.) Berger Flavonoids Flavones Source classification Crassulaceae Plants Saccharides Monosaccharides	Others
Sinocrassoside C1 is a natural compound isolated from themethanolic extract of the whole plant ofSinocrassula indica (Crassulaceae) ^[1].

HY-129151

Ganoderic acid C1	Triterpenes Structural Classification Classification of Application Fields Terpenoids Polyporaceae Source classification Ganoderma lucidum (Leyss. Ex Fr.) Karst. Plants Inflammation/Immunology Disease Research Fields	TNF Receptor
Ganoderic acid C1, a natural compound that could be isolated from G. lucidum, suppresses TNF-α production by murine macrophages (RAW 264.7 cells) ^[1].

HY-B0987

Ascorbyl palmitate 3 Publications Verification L-Ascorbic acid 6-hexadecanoate; 6-O-Palmitoyl-L-Ascorbic acid	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Cancer	Reactive Oxygen Species Endogenous Metabolite Calcium Channel Sodium Channel Apoptosis NOD-like Receptor (NLR) Bcl-2 Family Caspase
Ascorbyl palmitate is an orally active ester formed from ascorbic acid and palmitic acid, used as an antioxidant and food additive. Ascorbyl palmitate in preventing fat and oil oxidation is more efficient than Butylated hydroxyanisole (HY-B1066) and Butylated hydroxytoluene (HY-Y0172). Ascorbyl palmitate mitigates inhibition of collagen synthesis by select calcium and sodium channel blockers. Ascorbyl palmitate induces Apoptosis in human umbilical vein endothelial cells (HUVECs). Ascorbyl palmitate ameliorates inflammatory diseases by inhibition of NLRP3 inflammasome ^[1] .

HY-B0987R

Ascorbyl palmitate (Standard) L-Ascorbic acid 6-hexadecanoate (Standard); 6-O-Palmitoyl-L-Ascorbic acid (Standard)	Structural Classification Natural Products Source classification Endogenous metabolite	Reactive Oxygen Species Endogenous Metabolite
Ascorbyl palmitate (Standard) is the analytical standard of Ascorbyl palmitate. This product is intended for research and analytical applications. Ascorbyl palmitate is an ester formed from ascorbic acid and palmitic acid creating an vitamin C, it is also used as an antioxidant food additive.

HY-P1645

Papain 5+ Cited Publications	Carica papaya L. Structural Classification Natural Products Classification of Application Fields Source classification Caricaceae Plants Inflammation/Immunology Disease Research Fields	Cathepsin
Papain is a cysteine protease of the peptidase C1 family, which is used in food, pharmaceutical, textile, and cosmetic industries.

HY-17564

2'-Deoxycytidine hydrochloride 5+ Cited Publications 2'-Deoxycytidine monohydrochloride; Deoxycytidine hydrochloride; NSC 83251	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite Nucleoside Antimetabolite/Analog
2'-Deoxycytidine hydrochloride is composed of the purine nucleoside guanine linked by its N9 nitrogen to the C1 carbon of deoxyribose.

HY-N12231

Carbazomycin B	Structural Classification Monophenols Microorganisms Source classification Phenols	Antibiotic Bacterial Lipoxygenase
Carbazomycin B is a bacterial metabolite and can be isolated from Streptomyces. Carbazomycin B is an antifungal and antibacterial agent. Carbazomycin B inhibits 5-lipoxygenase (5-LO) activity in extract from RBL-1 cell with the IC₅₀ Of 1.5 µM ^[1]sup>[2]sup>[3]sup>[4].

HY-N6958

*2-O-β-D-Glucopyranosyl-L-ascorbic* acid** 1 Publications Verification AA-2βG	Structural Classification Classification of Application Fields Source classification Metabolic Disease Solanaceae Plants Lycium chinense Miller Disease Research Fields Saccharides	Others
2-O-β-D-Glucopyranosyl-L-ascorbic acid (AA-2βG), isolated from Lycium chinense, is a stable vitamin C analog with anti-tumor activity ^[1].

HY-N11122

7-[α-L-Arabinopyranosyl-(1→6)-β-D-glucopyranosyloxy]cuminol	Structural Classification Natural Products Rhodiola rosea Linn. Source classification Crassulaceae Plants	Others
7-[α-L-Arabinopyranosyl-(1→6)-β-D-glucopyranosyloxy]cuminol is a cuminol glycoside. 7-[α-L-Arabinopyranosyl-(1→6)-β-D-glucopyranosyloxy]cuminol can be isolated from Rhodiola rosea sup>[1].

HY-148286R

Gentamicin C1a (Standard)	Microorganisms Source classification	Antibiotic Bacterial
Gentamicin C1a (Standard) is the analytical standard of Gentamicin C1a. This product is intended for research and analytical applications. Gentamicin C1a is the precursor of the semi-synthetic antibiotic Etimicin, and has antibacterial activity. Gentamicin C1a is the major component of the Gentamicin complex ^[1] .

HY-105231

Bryostatin 1 2 Publications Verification	Structural Classification Anti-inflammation/Immunoregulatory Neurological Disease Classification of Application Fields Marine natural products Source classification Other marine organisms Disease Research Infection Macrolide Antibiotics Animals Antibiotics Anticancer Inflammation/Immunology Disease Research Fields	PKC HIV Bacterial
Bryostatin 1 is a natural macrolide isolated from the bryozoan Bugula neritina and is a potent and central nervous system (CNS)-permeable PKC modulator. Bryostatin 1 binds to the isolated C1 domain of *Munc13-1* and the full-length *Munc13-1* protein with K_is of 8.07 nM and 0.45 nM, respectively. Bryostatin 1 has anti-cancer, anti-inflammatory, neuroprotective, anti-HIV-1 infection properties ^[1] .

HY-N8824

Maackiaflavanone	Structural Classification Flavonoids Leguminosae Flavonones Source classification Maackia amurensis Rupr. et Maxim. Plants	Others
Maackiaflavanone (compound 4) is a kind of prenylated flavanone. Maackia can be isolated from M. amurensi.

HY-N3872

Ethyl β-D-glucopyranoside	Scabiosa stellata L. Structural Classification Natural Products Caprifoliaceae Source classification Plants	Others
Ethyl β-D-glucopyranoside (compound 10) is a kind of phenolic compound. Ethyl β-D-glucopyranoside can be isolated from ethanolic extract of Scabiosa stellata LS.

HY-N8859

Isoiridogermanal 16-Hydroxyiridal	Structural Classification Natural Products Source classification Lridaceae Plants	Others
Isoiridogermanal can be isolated from the extract of rhizomes of Iris tectorum Maxim. Isoiridogermanal is cytotoxic with IC50 values of 11 μM and 23 μM against MCF-7 and C32 cell lines.

HY-153830

LacCer (d18:1/16:0) C16 Lactosylceramide (d18:1/16:0)	Structural Classification Microorganisms Source classification Saccharides Monosaccharides	Endogenous Metabolite
LacCer (d18:1/16:0) (C16 Lactosylceramide (d18:1/16:0)) is an endogenous bioactive sphingolipid that can form membrane microdomains with Lyn kinase and the αi subunits of inhibitory G protein-coupled receptors (GPCRs). The levels of LacCer (d18:1/16:0) are elevated in the plasma of insulin-resistant cattle. In a mouse model of Niemann-Pick type C1 disease (a neurodegenerative cholesterol-sphingolipid lysosomal storage disorder), the expression of LacCer (d18:1/16:0) is also upregulated. LacCer (d18:1/16:0) can be used in research on metabolic diseases and neurodegenerative diseases ^[1] .

HY-N3980

Guaiol Champacol; Guaiac alcohol	Infection Structural Classification Natural Products Classification of Application Fields Source classification Distemonanthus benthamianus Baill. Plants Compositae Disease Research Fields	Autophagy RAD51
Guaiol is a sesquiterpenoid alcohol with oral activity found in various traditional Chinese medicines, exhibiting biological activities such as anti-proliferative, autophagy-promoting, insecticidal, anti-anxiety, anti-inflammatory, diuretic, and blood pressure-lowering effects. Guaiol induces apoptosis in non-small cell lung cancer cells by regulating the stability of RAD51 through autophagy modulation. Guaiol can also act directly on parasites, inhibiting their growth by affecting the kinetoplast, mitochondrial matrix and plasma membrane of the promastigotes. Guaiol kills amastigotes at an IC₅₀ of 0.01 µg/mL. Guaiol can be used in research related to cancer, infections, cardiovascular diseases, and inflammatory conditions ^[1] ^{[4]sup .}

HY-N8930

Eupatorin-5-methyl ether	Structural Classification Flavonoids Flavones Labiatae Source classification Plants Swartzia polyphylla DC.	Others
Eupatorin-5-methyl ether (TMF) can be isolated from Orthosiphon stamineus. Eupatorin-5-methyl ether is a kind of flavonoid compound. Eupatorin-5-methyl ether inhibits NO production (IC50 5.5 μM).

HY-N3980R

Guaiol (Standard)	Structural Classification Natural Products Source classification Distemonanthus benthamianus Baill. Plants Compositae	Autophagy RAD51
Guaiol (Standard) is the analytical standard of Guaiol. This product is intended for research and analytical applications. Guaiol is a sesquiterpenoid alcohol with oral activity found in various traditional Chinese medicines, exhibiting biological activities such as anti-proliferative, autophagy-promoting, insecticidal, anti-anxiety, anti-inflammatory, diuretic, and blood pressure-lowering effects. Guaiol induces apoptosis in non-small cell lung cancer cells by regulating the stability of RAD51 through autophagy modulation. Guaiol can also act directly on parasites, inhibiting their growth by affecting the kinetoplast, mitochondrial matrix and plasma membrane of the promastigotes. Guaiol kills amastigotes at an IC50 of 0.01 µg/mL. Guaiol can be used in research related to cancer, infections, cardiovascular diseases, and inflammatory conditions ^[1] ^[3][4] .

HY-W016628

L-Gulono-1,4-lactone L-Gulonolactone	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Saccharides	Endogenous Metabolite
L-Gulono-1,4-lactone is a substrate of L-gulono-1,4-lactone oxidoreductase, which catalyzes the last step of the biosynthesis of L-ascorbic (Vatamin) C. In other words, L-Gulono-1,4-lactone is a direct precursor of vitamin C in animals, in plants and in some protists.

HY-N10886

Eupatolitin Eupatoletin	Structural Classification Flavonols Flavonoids Source classification Centaurea aspera stenophylla Plants Umbelliferae	Others
Eupatoletin is a flavonol compound isolated from Eupatorium ligustrinum D.C. .

HY-N0376

Liquiritin 5+ Cited Publications	Structural Classification Neurological Disease Classification of Application Fields Source classification Plants Monophenols Flavonoids Leguminosae Flavonones Phenols Glycyrrhiza uralensis Fisch. Inflammation/Immunology Disease Research Fields	Reactive Oxygen Species
Liquiritin, a flavonoid isolated from Glycyrrhiza uralensis, is a potent and competitive *AKR1C1* inhibitor with IC₅₀s of 0.62 μM, 0.61 μM, and 3.72μM for AKR1C1, AKR1C2 and AKR1C3, respectively. Liquiritin efficiently inhibits progesterone metabolism mediated by AKR1C1 in vivo ^[1]. Liquiritin acts as an antioxidant and has neuroprotective, anti-cancer and anti-inflammatory activity .

HY-N12499

Eupalitin	Structural Classification Flavonols Flavonoids Melilotus albus Desr. Source classification Plants Compositae	Others
Eupalitin, flavonol, is an active natural product. Eupalitin can be isolated from Eupatorium ligustrinum D.C .

HY-N0376R

Liquiritin (Standard)	Structural Classification Monophenols Flavonoids Leguminosae Flavonones Source classification Phenols Plants Glycyrrhiza uralensis Fisch.	Reactive Oxygen Species
Liquiritin (Standard) is the analytical standard of Liquiritin. This product is intended for research and analytical applications. Liquiritin, a flavonoid isolated from Glycyrrhiza uralensis, is a potent and competitive AKR1C1 inhibitor with IC50s of 0.62 μM, 0.61 μM, and 3.72μM for AKR1C1, AKR1C2 and AKR1C3, respectively. Liquiritin efficiently inhibits progesterone metabolism mediated by AKR1C1 in vivo ^[1]. Liquiritin acts as an antioxidant and has neuroprotective, anti-cancer and anti-inflammatory activity .

HY-128394

L-Gulose	Structural Classification Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Saccharides Monosaccharides	Endogenous Metabolite
L-Gulose, the putative furanose form of L-sorbosone, is an L-hexose sugar and an intermediate in the biosynthesis of L-Ascorbate (vitamin C) .

HY-N9386

Tellimagrandin II 1 Publications Verification Eugeniin	Structural Classification Classification of Application Fields Source classification Myriophyllum spicatum L. Phenols Polyphenols Haloragaceae Plants Inflammation/Immunology Disease Research Fields	Bacterial Antibiotic
Tellimagrandin II (Eugeniin), with oral activity, is the first intermediate of the ellagitannin series derived from ⁴C₁-glucose. It inhibits the resistance of Staphylococcus aureus by disrupting the integrity of the cell wall, leading to the loss of cytoplasmic contents. Additionally, Tellimagrandin II exhibits anti-inflammatory effects and inhibits acetylcholinesterase (AChE) activity, improving memory impairment. Tellimagrandin II holds potential for research in the fields of antibacterial, anti-inflammatory, and neurodegenerative diseases ^[1] .

HY-I0736

Isonicotinic acid	Alkaloids Aloe africana Liliaceae Source classification Other Diseases Pyridine Alkaloids Plants Disease Research Fields	Drug Metabolite Endogenous Metabolite
Isonicotinic acid is a metabolite of Isoniazid. Isoniazid is converted to Isonicotinic acid by hydrazinolysis, with the Isoniazid to Isonicotinic acid biotransformation also to be catalyzed by cytochrome P450 (CYP) enzymes, e.g., CYP2C .

HY-N10344

Glucoarabin	Structural Classification Natural Products Classification of Application Fields Source classification Camelina sativa (L.) Crantz Glucosinolates Plants Brassicaceae Disease Research Fields Cancer	Cytochrome P450
Glucoarabin is a bioactive glucosinolate. In Hepa1c1c7 cells, hydrolyzed Glucoarabin (hGSL 9) upregulates the phase II detoxification enzyme quinone reductase (NQO1), with no effect on cytochrome P450 (CYP) 1A1 activity ^[1].

HY-I0736R

Isonicotinic acid (Standard)	Alkaloids Aloe africana Liliaceae Source classification Pyridine Alkaloids Plants	Drug Metabolite Endogenous Metabolite
Isonicotinic acid (Standard) is the analytical standard of Isonicotinic acid. This product is intended for research and analytical applications. Isonicotinic acid is a metabolite of Isoniazid. Isoniazid is converted to Isonicotinic acid by hydrazinolysis, with the Isoniazid to Isonicotinic acid biotransformation also to be catalyzed by cytochrome P450 (CYP) enzymes, e.g., CYP2C .

HY-N9934R

(-)-3-Dehydroshikimic acid (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Others
Isonicotinic acid (Standard) is the analytical standard of Isonicotinic acid. This product is intended for research and analytical applications. Isonicotinic acid is a metabolite of Isoniazid. Isoniazid is converted to Isonicotinic acid by hydrazinolysis, with the Isoniazid to Isonicotinic acid biotransformation also to be catalyzed by cytochrome P450 (CYP) enzymes, e.g., CYP2C .

HY-N1967

Dihydrocurcumin	Zingiber officinale Roscoe Structural Classification Microorganisms Classification of Application Fields Source classification Phenols Polyphenols Metabolic Disease Plants Disease Research Fields Zingiberaceae	Fatty Acid Synthase (FASN)
Dihydrocurcumin, a major metabolites of curcumin, reduces lipid accumulation and oxidative stress. Dihydrocurcumin regulates mRNA and protein expression levels of SREBP-1C, PNPLA3 and PPARα, increases protein expression levels of pAKT and PI3K, and reduced the levels of cellular NO and ROS via Nrf2 signaling pathways ^[1].

HY-N6802

Tigloylgomisin H	Structural Classification Classification of Application Fields Source classification Lignans Phenylpropanoids Plants Schisandraceae Schisandra chinensis (Turcz.) Baill. Disease Research Fields Cancer	Keap1-Nrf2
Tigloylgomisin H is a lignan isolated from the fruits of S. chinensis, can induce quinone reductase (QR) activity in Hepa1c1c7 mouse hepatocarcinoma cells. Tigloylgomisin H functions as a monofunctional inducer that specifically upregulates phase II detoxification enzyme NQO1 through the NF-E2-related factor 2 (Nrf2)-ARE pathway, thus represents a potential liver cancer prevention agent ^[1].

HY-131586

3,7-Dihydroxyflavone Resogalangin	Structural Classification Flavonoids Flavones Source classification Plants Fabaceae Zuccagnia punctata Cav.	17β-HSD Estrogen Receptor/ERR Aldose Reductase
3,7-Dihydroxyflavone (Resogalangin) is a flavonoid phytoestrogen, which can be isolated from Adenophora species. 3,7-Dihydroxyflavone is a modulator of estrogen receptors and an inhibitor of human progesterone metabolizing enzyme *AKR1C1* and fungal 17β-hydroxysteroid dehydrogenase and a redox inhibitor (IC₅₀=0.6 and 6.0 μM, respectively). 3,7-Dihydroxyflavone is a fluorescent binding substrate for human serum albumin (HSA) with excitation wavelengths of 370 nm (pH 7.4) and 350 nm (pH 3.5), respectively, and emission wavelength of 515 nm ^[1] .

HY-Y1091

D-Lysine	Structural Classification Classification of Application Fields Source classification Other Diseases Amino acids Endogenous metabolite Disease Research Fields	Endogenous Metabolite
D-Lysine is a useful raw material employed as an analog of lutenizing-hormone-releasing hormone and as a agent carrier in the form of polylysine. D-Lysine decreases renal uptake of radioactivity during scintigraphy and PRRT with low toxicity. D-Lysine not interferes with the natural amino acid metabolic balance ^[1] .

Cat. No.	Product Name	Chemical Structure

HY-B0166S1

L-Ascorbic acid-13C

L-Ascorbic acid- ¹³C is the ¹³C-labeled L-Ascorbic acid. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor[1][2][3]. L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells[4].

HY-B0166S3

L-Ascorbic acid-13C-2
L-Ascorbic acid- ¹³C-2 is the ¹³C labeled L-Ascorbic acid. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen

HY-B0166S

L-Ascorbic acid-13C6

L-Ascorbic acid- ¹³C₆ is the ¹³C-labeled L-Ascorbic acid. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor[1][2][3]. L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells[4].

HY-B0166S8

L-Ascorbic acid-13C6-1

L-Ascorbic acid- ¹³C₆-1 (L-Ascorbate-1; Vitamin C- ¹³C₆-1) is a ¹³C labeled L-Ascorbic acid (HY-B0166) ^[1]. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Ca_v3.2 channels with an IC₅₀ of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor . L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells .

HY-B0166S2

L-Ascorbic acid-13C-1
L-Ascorbic acid- ¹³C-1 is the ¹³C labeled L-Ascorbic acid. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen

HY-B0166S4

L-Ascorbic acid-13C-3
L-Ascorbic acid- ¹³C-3 is the ¹³C labeled L-Ascorbic acid. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen

HY-B0166S5

L-Ascorbic acid-13C-4
L-Ascorbic acid- ¹³C-4 is the ¹³C labeled L-Ascorbic acid. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collag

HY-B0166S6

L-Ascorbic acid-d2
L-Ascorbic acid-d₂ is the deuterium labeled L-Ascorbic acid. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a colla

HY-Y0418S1

Dulcite-13C-1
Dulcite- ¹³C-1 is the ¹³C labeled Dulcite. Dulcite is a sugar alcohol with a slightly sweet taste which is a metabolic breakdown product of galact[1][2].

HY-N1480S1

(-)-Fucose-13C-1
(-)-Fucose- ¹³C-1 is the ¹³C labeled (-)-Fucose. (-)-Fucose is classified as a member of the hexoses, plays a role in A and B blood group antigen substructure determination, selectin-mediated leukocyte-endothelial adhesion, and host-microbe interacti[

HY-B0389S11

D-Glucose-13C-1
D-Glucose- ¹³C-1 is the ¹³C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].

HY-I0400S1

N-Acetylneuraminic acid-13C-1
N-Acetylneuraminic acid- ¹³C-1 is the ¹³C labeled N-Acetylneuraminic acid.

HY-N1150S3

Thymidine-13C-1
Thymidine- ¹³C-1 is the ¹³C labeled Thymidine. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication[1]

HY-B0400S2

D-Sorbitol-13C-1
D-Sorbitol- ¹³C-1 is the ¹³C labeled D-Sorbitol. D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and dietary

HY-N0305S3

5-Aminolevulinic acid-13C-1 hydrochloride
5-Aminolevulinic acid- ¹³C-1 (5-ALA- ¹³C-1) hydrochloride is the ¹³C labeled 5-Aminolevulinic acid hydrochloride ^[1]. 5-Aminolevulinic acid hydrochloride (5-ALA hydrochloride) is an intermediate in heme biosynthesis in the body and the universal precursor of tetrapyrroles .

HY-77956S1

Thyminose-13C-1
Thyminose- ¹³C-1 is the ¹³C labeled Thyminose. Thyminose is an endogenous metabolite[1].

HY-128850S2

N-Acetyl-D-mannosamine-13C-1
N-Acetyl-D-mannosamine- ¹³C-1 is the ¹³C labeled N-Acetyl-D-mannosamine. N-Acetyl-D-mannosamine (ManNAc) is an essential precursor of N-acetylneuraminic acid (NeuAc), the specific monomer of bacterial capsular polysialic acid (PA)[1][2]

HY-B1659S2

Glycerol-13C-1
Glycerol- ¹³C-1 is the ¹³C labeled Glycerol. Glycerol is used in sample preparation and gel formation for polyacrylamide gel electrophoresis[1][2][3][4].

HY-13966S4

2-Deoxy-D-glucose-13C-1
2-Deoxy-D-glucose- ¹³C-1 is the ¹³C labeled 2-Deoxy-D-glucose. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase[1][2].

HY-111095S2

D-(-)-Lactic acid-13C-1
D-(-)-Lactic acid- ¹³C-1 is the ¹³C labeled D-(-)-Lactic acid. D-(-)-Lactic acid is a normal intermediate in the fermentation (oxidation, metabolism) of sugar. D-(-)-Lactic acid is identified to be a competitive inhibitor of ProDH (proline dehydrogenase) in plants ^[1].

HY-B2227BS3

Lactate-13C-1 sodium
Lactate- ¹³C-1 (sodium) is the ¹³C labeled Lactate (sodium)[1]. Lactate (Lactic acid) sodium is the product of glycogenolysis and glycolysis. Lactate (Lactic acid) sodium functions in a variety of biochemical processes[2].

HY-B1449S2

Uridine-13C-1
Uridine- ¹³C-1 is the ¹³C labeled Uridine[1].

HY-B0158S2

Cytidine-13C-1
Cytidine- ¹³C-1 is the ¹³C labeled Cytidine. Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catecholami

HY-N7092S2

D-Fructose-13C-1
D-Fructose- ¹³C-1 is the ¹³C labeled D-Fructose. D-Fructose (D(-)-Fructose) is a naturally occurring monosaccharide found in many plants.

HY-W010042S1

L-Glucose-13C-1
L-Glucose- ¹³C-1 is the ¹³C labeled L-Glucose. L-Glucose (L-(-)-Glucose) is an enantiomer of D-glucose. L-Glucose can promote food intake[1][2].

HY-42680S1

D-Tagatose-13C-1
D-Tagatose- ¹³C-1 is the ¹³C labeled D-Tagatose. D-Tagatose (D-(-)-Tagatose) is a rare monosaccharide found in nature with prebiotic characteristics. D-Tagatose is as a substitute for sucrose and a low-calorie sweetener in foodstuffs such as gum, fruit jui

HY-N2362S

DL-Alanine-13C-1

DL-Alanine- ¹³C-1 is the ¹³C-labeled DL-Alanine. DL-alanine, an amino acid, is the racemic compound of L- and D-alanine. DL-alanine is employed both as a reducing and a capping agent, used with silver nitrate aqueous solutions for the production of nanoparticles. DL-alanine can be used for the research of transition metals chelation, such as Cu(II), Zn(II), Cd(11). DL-alanine, a sweetener, is classed together with glycine, and sodium saccharin. DL-alanine plays a key role in the glucose-alanine cycle between tissues and liver[1][2][3][4][5][6].

HY-A0132S2

N-Acetyl-D-glucosamine-13C-1
N-Acetyl-D-glucosamine- ¹³C-1 is the ¹³C labeled N-Acetyl-D-glucosamine. N-Acetyl-D-Glucosamine (N-Acetyl-2-amino-2-deoxy-D-glucose) is a monosaccharide derivative of gluc[1][2].

HY-W015824S3

DL-Aspartic acid-13C1
DL-Aspartic acid- ¹³C₁ is the ¹³C labeled DL-Aspartic acid[1].

HY-15306S

Eltrombopag-13C4

1 Publications Verification

Eltrombopag- ¹³C₄ (SB-497115- ¹³C₄) is ^{13 sup>C-labeled Z-Eltrombopag. Z-Eltrombopag is an orally active thrombopoietin-receptor non-peptide agonist with platelet-stimulating activity for the study of chronic immune thrombocytopenia. Eltrombopag also has strong inhibitory effects on multidrug-resistant Staphylococcus aureus (Staphylococcus aureus) and can induce apoptosis (apoptosis) in liver cancer cells ^[1] .}

HY-Y0418S

Dulcite-13C
Dulcite- ¹³C is the ¹³C labeled Dulcite. Dulcite is a sugar alcohol with a slightly sweet taste which is a metabolic breakdown product of galact[1][2].

HY-13771S1

Ursodeoxycholic acid-13C

Ursodeoxycholic acid- ¹³C is the ¹³C labeled Ursodeoxycholic acid. Ursodeoxycholic acid (Ursodeoxycholate) is a secondary bile acid issued from the transformation of (cheno)deoxycholic acid by intestinal bacteria, acting as a key regulator of the intestinal barrier integrity and essential for lipid metabolism. Ursodeoxycholic acid acts as signaling molecule, exerting its effects by interacting with bile acid activated receptors, including G-protein coupled bile acid receptor 5 (TGR5, GPCR19) and the farnesoid X receptor (FXR). Ursodeoxycholic acid can be used for the research of a variety of hepatic and gastrointestinal diseases. Orally active[1][2].

HY-B0389S10

D-Glucose-13C
D-Glucose- ¹³C is the ¹³C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].

HY-N0666S10

L-Aspartic acid-C13-1
L-Aspartic acid- ¹³C-1 is the deuterium labeled L-Aspartic acid[1]. L-Aspartic acid is is an amino acid, shown to be a suitable proagent for colon-specific agent deliverly[2][3].

HY-N1480S

(-)-Fucose-13C
(-)-Fucose- ¹³C is the ¹³C labeled (-)-Fucose. (-)-Fucose is classified as a member of the hexoses, plays a role in A and B blood group antigen substructure determination, selectin-mediated leukocyte-endothelial adhesion, and host-microbe interacti[1]

HY-W654136

2'-Deoxycytidine-2'-13C
2'-Deoxycytidine-2'- ¹³C is ¹³C labeled 2'-Deoxycytidine. 2'-Deoxycytidine, a deoxyribonucleoside, can inhibit biological effects of Bromodeoxyuridine (Brdu). 2'-Deoxycytidine is essential for the synthesis of nucleic acids, that can be used for the research of cancer ^[1] .

HY-Y0842S

Formamide-13C
Formamide- ¹³C is the ¹³C-labeled Formamide. Formamide is an amide derived from formic acid and has been used as solvent for many ionic compounds.

HY-N0623S1

L-Tryptophan-13C
L-Tryptophan- ¹³C is the ¹³C-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1].

HY-N0378S1

D-Mannitol-13C
D-Mannitol- ¹³C is the ¹³C labeled D-Mannitol[1][2][3][4].

HY-N0733S

Glucosamine-13C hydrochloride
Glucosamine- ¹³C (hydrochloride) is the ¹³C labeled Glucosamine hydrochloride. Glucosamine hydrochloride (D-Glucosamine hydrochloride) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a

HY-N1150S2

Thymidine-13C
Thymidine- ¹³C is the ¹³C labeled Thymidine. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication[1]

HY-N0667S4

L-Asparagine-4-13C monohydrate
L-Asparagine-4- ¹³C (monohydrate) is the ¹³C-labeled L-Asparagine. L-Asparagine ((-)-Asparagine) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue.

HY-Y0418S2

Dulcite-13C-2
Dulcite- ¹³C-2 is the ¹³C labeled Dulcite. Dulcite is a sugar alcohol with a slightly sweet taste which is a metabolic breakdown product of galact[1][2].

HY-Y0418S3

Dulcite-13C-3
Dulcite- ¹³C-3 is the ¹³C labeled Dulcite. Dulcite is a sugar alcohol with a slightly sweet taste which is a metabolic breakdown product of galact[1][2].

HY-B0617S1

S-Adenosyl-L-methionine-13C

S-Adenosyl-L-methionine- ¹³C is the ¹³C labeled S-Adenosyl-L-methionine[1]. S-Adenosyl-L-methionine (S-Adenosyl methionine) is produced endogenously from methionine and ATP by action of the enzyme methionine adenosyltransferase and is an important orally active methyl group donor. S-Adenosyl-L-methionine is a dietary supplement with potent antidepressant effects, and has the potential for liver disease and osteoarthritis research[2][3][4].

HY-B0617S2

S-Adenosyl-L-methionine-13C dihydrochloride

S-Adenosyl-L-methionine- ¹³C (S-Adenosyl methionine- ¹³C) dihydrochloride is the ¹³C labeled S-Adenosyl-L-methionine (HY-B0617). S-Adenosyl-L-methionine (S-Adenosyl methionine) is an orally active methyl group donor. S-Adenosyl-L-methionine is a dietary supplement with potent antidepressant effects. S-Adenosyl-L-methionine also has anti‑proliferative, pro‑apoptotic and anti‑metastatic roles in cancers. S-Adenosyl-L-methionine has the potential for, cancer, liver disease and osteoarthritis research ^[1] .

HY-B0389S12

D-Glucose-13C-2
D-Glucose- ¹³C-2 is the ¹³C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].

HY-B0389S16

D-Glucose-13C-4
D-Glucose- ¹³C-4 is the ¹³C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].

HY-B0389S17

D-Glucose-13C-5
D-Glucose- ¹³C-5 is the ¹³C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].

HY-B0389S13

D-Glucose-13C-3
D-Glucose- ¹³C-3 is the ¹³C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].

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