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substrates

" in MedChemExpress (MCE) Product Catalog:

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By Research Areas:	Cancer (333) Cardiovascular Disease (68) Endocrinology (22) Infection (121) Inflammation/Immunology (140) Metabolic Disease (224) Neurological Disease (118)
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Oligonucleotides:	Nucleotides and their Analogs (7) Nucleosides and their Analogs (2) Cosolvents (1) Emulsifiers (1) Solubilizing Agents (1) Surfactants (1) Polymers (1) Antisense Oligonucleotides (2) Cap Analogs (2) pH Modifiers (1)

1725

Inhibitors & Agonists

Screening Libraries

180

Fluorescent Dye

347

Biochemical Assay Reagents

625

Peptides

MCE Kits

Inhibitory Antibodies

175

Natural
Products

Isotope-Labeled Compounds

Click Chemistry

Oligonucleotides

IDT307	Fluorescent Dye	Others
IDT307, an analog of the organic cation MPP+, is a specific fluorescent substrate for DAT (fluorescent substrate APP+) .

Z-DEVD-AMC	Caspase	Cancer
Z-DEVD-AMC is a selective caspase-3 substrate that can be measured by fluorescence spectrometry. AMC can be used as a fluorescence reference standard for AMC-based enzyme substrates including AMC-based caspase substrates .

Resorufin methyl ether Methoxyresorufin	Cytochrome P450	Others
Resorufin methyl ether (Methoxyresorufin) is a cytochrome P450 fluorometric substrate . Resorufin methyl ether is a relatively specific substrate for CYP1A2 activity in rodents .

Lumigen APS-5	Phosphatase	Infection
Lumigen APS-5 is a substrate of alkaline phosphatase (ALP). Lumigen APS-5 can be used to assess the activity of alkaline phosphatase (ALP) .

L-Arginine-7-amido-4-methylcoumarin hydrochloride Arginine 4-methyl-7-coumarylamide hydrochloride	Cathepsin	Others
L-Arginine-7-amido-4-methylcoumarin (Arginine 4-methyl-7-coumarylamide) hydrochloride is a specific substrate of cathepsin H but not for cathepsins L and B .

Pseudopelletierine	Biochemical Assay Reagents	Others
Pseudopelletierine is an alkaloid compound that can be used as a enzyme substrate .

3-Acetylumbelliferyl β-D-Glucopyranoside	Fluorescent Dye	Metabolic Disease Inflammation/Immunology
3-Acetylumbelliferyl β-D-Glucopyranoside is a fluorogenic substrate for β-glucosidase and can be used as a positive control substrates for β-D-glucosidase .

Naphthol AS-BI phosphate	Biochemical Assay Reagents	Others
Naphthol AS-BI phosphate is a substrate for acid and alkaline phosphatase and can be used in fluorescence assays. Naphthol AS-BI phosphate is a kind of biological materials or organic compounds that are widely used in life science research .

MUF-diNAG 4-Methylumbelliferyl N,N-diacetyl-β-D-chitobioside	Biochemical Assay Reagents	Others
MUF-diNAG (4-Methylumbelliferyl N,N-diacetyl-β-D-chitobioside) can be used as a fluorescent substrate. MUF-diNAG is a kind of biological materials or organic compounds that are widely used in life science research .

6-Chloro-3-indoxyl-α-D-mannopyranoside	Fluorescent Dye	Others
6-Chloro-3-indoxyl-α-D-mannopyranoside is a chromogenic substrate for α-mannosidase resulting in a salmon colored precipitate upon cleavage.

5-Bromo-1H-indol-3-yl octanoate	Fluorescent Dye	Others
5-Bromo-1H-indol-3-yl octanoate is a chromogenic substrate for esterase with C8 activity. 5-Bromo-1H-indol-3-yl octanoate yields a blue precipitate when cleaved.

4-Methylumbelliferyl β-cellotrioside	Fluorescent Dye	Metabolic Disease
4-Methylumbelliferyl β-cellotrioside, a chromogenic substrate for β-glycosidases, is a cellulose fluorescent derivative .

Hippuryl-L-phenylalanine	Carboxypeptidase	Cancer
Hippuryl-L-phenylalanine is a substrate of carboxypeptidase. Carboxypeptidase is a protease enzyme that related with obesity, epilepsy and neurodegeneration. Hippuryl-L-phenylalanine can be used for the determination of carboxypeptidase activity .

7-Ethoxyresorufin 1 Publications Verification Resorufin ethyl ether	Cytochrome P450 NO Synthase	Others
7-Ethoxyresorufin (Resorufin ethyl ether) is a fluorometric substrate and competitive inhibitor of cytochrome P450, especially CYP1A1. 7-Ethoxyresorufin also inhibits NO synthase .

Stearoyl coenzyme A lithium Stearoyl-CoA lithium	Biochemical Assay Reagents	Others
Stearoyl coenzyme A (Stearoyl-CoA) lithium is an active compound that can be used as a substrate for the determination of stearoyl-Coenzyme desaturase in microsomes .

4-Nitrophenyl α-D-galactopyranoside PNP-alpha-D-Gal; PNP-α-D-Gal	Biochemical Assay Reagents	Others
4-Nitrophenyl α-D-galactopyranoside (PNP-alpha-D-Gal) is an artificial substrate of 4-nitrophenyl (pNP) glycopyranoside for detecting α-galactosidase activity. The amount of released pNP is significantly increased when 4-Nitrophenyl α-D-galactopyranoside is used as substrates .

4-Methylumbelliferyl phosphate 4-MUP; MUP	Phosphatase	Others
4-Methylumbelliferyl phosphate (4-MUP), an anionic organophosphate, is a acid and alkaline phosphatase fluorogenic substrate. 4-Methylumbelliferyl phosphate is also a nerve agent simulant .

Cathepsin D and E FRET Substrate	Cathepsin	Others
Cathepsin D and E FRET Substrate is a fluorogenic substrate for cathepsins D and E and not for B, H or L. The cleavage occurs at the Phe-Phe amide bond resul. Cathepsin D and E FRET Substrate is a valuable tool for routine assays and for mechanistic studies on cathepsins E and D .

*Cathepsin D and E FRET Substrate* acetate**	Cathepsin	Cancer
Cathepsin D and E FRET Substrate acetate is a fluorogenic substrate for cathepsins D and E and not for B, H or L. The cleavage occurs at the Phe-Phe amide bond resul. Cathepsin D and E FRET Substrate is a valuable tool for routine assays and for mechanistic studies on cathepsins E and D .

Prostate Specific Antigen Substrate	PSMA	Cancer
Prostate Specific Antigen Substrate is a prostate specific antigen (PSA) fluorescent substrate. Prostate Specific Antigen Substrate can be used for detect enzymatic activity of PSA .

Suc-Ala-Glu-Pro-Phe-pNA Suc-AEPF-pNA	Biochemical Assay Reagents	Others
Suc-Ala-Glu-Pro-Phe-pNA (Suc-AEPF-pNA) is a chromogenic substrate for the peptidylprolyl isomerase Pin1. Suc-Ala-Glu-Pro-Phe-pNA can be used to evaluate the inhibitory effect of the target compound on Pin1, and catalytic activity of Pin1, etc .

4-Nitrophenyl phosphate disodium hexahydrate 3 Publications Verification p-Nitrophenyl phosphate disodium hexahydrate	Biochemical Assay Reagents	Others
4-Nitrophenyl phosphate (p-nitrophenyl phosphate) disodium hexahydrate is widely used as a small molecule phosphotyrosine-like substrate in activity assays for protein tyrosine phosphatases. 4-Nitrophenyl phosphate disodium hexahydrate is a colorless substrate that upon hydrolysis is converted to a yellow 4-nitrophenolate ion that can be monitored by absorbance at 405 nm .

Suc-Ala-Glu-Pro-Phe-pNA TFA Suc-AEPF-pNA TFA	Biochemical Assay Reagents	Others
Suc-Ala-Glu-Pro-Phe-pNA (Suc-AEPF-pNA ) TFA is a chromogenic substrate for the peptidylprolyl isomerase Pin1. Suc-Ala-Glu-Pro-Phe-pNA TFA can be used to evaluate the inhibitory effect of the target compound on Pin1, and catalytic activity of Pin1, etc .

Calmodulin Dependent Protein Kinase Substrate	CaMK	Neurological Disease
Calmodulin Dependent Protein Kinase Substrate is a Ca ²⁺- and calmodulin (CaM)-dependent protein kinase (CaMK) substrate peptide. Calmodulin Dependent Protein Kinase Substrate is a synthetic peptide substrate for protein kinases .

H-L-Ile-Amc TFA	Biochemical Assay Reagents	Others
H-L-Ile-Amc (TFA) is an enzyme substrate, and can detect the yeasts and molds in the sample using aminopeptidase substrates .

*Calmodulin Dependent Protein Kinase Substrate* Analog**	CaMK	Neurological Disease
Calmodulin Dependent Protein Kinase Substrate Analog is a Ca ²⁺- and calmodulin (CaM)-dependent protein kinase (CaMK) substrate peptide. Calmodulin Dependent Protein Kinase Substrate Analog is a synthetic peptide substrate for protein kinases .

Suc-Arg-Pro-Phe-His-Leu-Leu-Val-Tyr-AMC Renin Substrate I	Renin	Others
Suc-Arg-Pro-Phe-His-Leu-Leu-Val-Tyr-AMC (Renin Substrate I) is a renin substrate

MMP-13 Substrate	MMP	Inflammation/Immunology
MMP-13 Substrate is a substrate of MMP-13. MMP-13 Substrate can be used for the research of osteoarthritis (OA) .

Z-Gly-Pro-AMC	Fluorescent Dye	Others
Z-Gly-Pro-AMC is a fluorogenic substrate. Z-Gly-Pro-AMC is hydrolyzed by prolyl endopeptidase to generate highly fluorescent 7-amido-4-methylcoumarin (HY-D0027). (λ_ex=380 nm, λ_em=465 nm) .

*MMP-13 Substrate* TFA**	MMP	Inflammation/Immunology
MMP-13 Substrate TFA is a substrate of MMP-13. MMP-13 Substrate TFA can be used for the research of osteoarthritis (OA) .

MeO-Succ-Arg-Pro-Tyr-AMC	Fluorescent Dye	Others
MeO-Succ-Arg-Pro-Tyr-AMC is an analogue of 7-amido-4-methylcoumarin (HY-D0027). MeO-Succ-Arg-Pro-Tyr-AMC is a sensitive fluorescent substrate chymotrypsin-like protease. (λ_ex=341 nm, λ_em=441 nm).

Naphthol AS-BI N-acetyl-β-D-glucosaminide	Biochemical Assay Reagents	Others
Naphthol AS-BI N-acetyl-β-D-glucosaminide acts as a substrate and reacts directly with N-acetyl-β-glucosaminidase enzyme. Naphthol AS-BI N-acetyl-β-D-glucosaminide can detect and localize the active region of N-acetyl-β-glucosaminidase enzyme visually .

ATP-polyamine-biotin 1 Publications Verification	Biochemical Assay Reagents	Others
ATP-polyamine-biotin, the first cell-permeable ATP analogue, is an efficient kinase cosubstrate. ATP-polyamine-biotin promotes biotin labeling of kinase substrates in live cells .

X-GAL 1 Publications Verification BCIG	Fluorescent Dye Glucosidase	Others
X-GAL (BCIG) is a widely used chromogenic β-galactosidase substrate. X-GAL is a colorless compound until cleaved by β-galactosidase, at which point X-GAL turns to an insoluble and detectable blue compound, making X-GAL particularly useful in techniques such as blue-white screening for cloning in bacteria. X-GAL can also be used for detection of β-galactosidase activity .

SEVNLDAEFR	Beta-secretase	Neurological Disease
SEVNLDAEFR is a substrate for BACE1 .

*DAPK Substrate* Peptide**	DAPK	Cancer
DAPK Substrate Peptide is a synthetic peptide substrate for death associated protein kinase (DAPK), with a K_m of 9 μM .

*Casein Kinase 2 Substrate* Peptide** 1 Publications Verification	Casein Kinase	Others
Casein Kinase 2 Substrate Peptide is a common CK2 substrate peptide. Casein Kinase 2 Substrate Peptide is synthesized with its C-terminus conjugated to 5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid (EDANS). Casein Kinase 2 Substrate Peptide can be used for protein kinase CK2 activity determination .

*DAPK Substrate* Peptide TFA**	DAPK	Cancer
DAPK Substrate Peptide TFA is a synthetic peptide substrate for death associated protein kinase (DAPK), with a K_m of 9 μM .

X-GalNAc	Fluorescent Dye	Infection
X-GalNAc is a chromogenic substrate for for N-acetyl-β-galactosidase, used to determine the presence or absence of a cloned DNA insert in bacteria growing on agar plates .

N-Benzoyl-L-tyrosine p-nitroanilide Bz-Try-pNA	Ser/Thr Protease	Others
N-Benzoyl-L-tyrosine p-nitroanilide is a chymotrypsin substrate .

iso-VQA-ACC TFA	Proteasome	Others
iso-VQA-ACC TFA is a constitutive proteasome substrate .

N-Acetyl-DL-phenylalanine β-naphthyl ester	Fluorescent Dye	Infection Metabolic Disease
N-Acetyl-DL-phenylalanine β-naphthyl ester is an aromatic amino acid ester, which functions as a chromogenic substrate for chymotrypsin and microbial serine proteases such as subtilisin .

*Fluorescent Substrate* for Glu-Specific Proteases**	Fluorescent Dye	Others
Fluorescent Substrate for Glu-Specific Proteases is a V8 protease-Specific chromogenic substrate .

Z-AA-R110-PEG	Biochemical Assay Reagents	Others
Z-AA-R110-PEG is a substrate for elastate.

4-Methylumbelliferyl α-L-arabinopyranoside 4-Methylumbelliferyl alpha-L-arabinopyranoside	Biochemical Assay Reagents	Others
4-Methylumbelliferyl α-L-arabinopyranoside (4-Methylumbelliferyl alpha-L-arabinopyranoside) is a substrate for enzymes that hydrolyze arabinose-containing substrates, such as α-L-arabinopyranoside .

*MMP-1/MMP-9 Substrate, Fluorogenic*	Fluorescent Dye MMP	Others
MMP-1/MMP-9 Substrate, Fluorogenic is a fluorogenic substrate for MMP-1 and MMP-9 .Ex/Em = 340/440 nm

Cat. No.	Product Name

HY-L906

Norepinephrine Transporter (NET) Compound Library

650 compounds

On May 15, 2024, "Dimerization and antidepressant recognition at noradrenaline transporter" was published online by Nature. The research findings were an effort from Shanghai Institute of Materia Medica, Chinese Academy of Sciences. This study unraveled the important neural system target - the noradrenaline transporter (NET), obtaining the binding modes of human NET homodimers with the natural substrate norepinephrine (NE) and six selective antidepressants. It laid an important theoretical foundation for understanding the physiological regulation mechanisms of NET and other monoamine transporters.

The Norepinephrine Transporter (NET) Compound Library is obtained by computer-aided virtual screening based on the HY-L901 compound library . The specific screening process includes molecular docking screening, key pharmacophore screening, and CNS-MPO screening, which can be used for new drug discovery targeting the noradrenaline transporter.

HY-L050

Ubiquitination Compound Library

258 compounds

Protein ubiquitination is an enzymatic post-translational modification in which an ubiquitin protein is attached to a substrate protein. Ubiquitination involves three main steps: activation, conjugation, and ligation, performed by ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s), and ubiquitin ligases (E3s), respectively. Ubiquitination affects cellular processes such as apoptosis, cell cycle, DNA damage repair, and membrane transportation, etc. by regulating the degradation of proteins (via the proteasome and lysosome), altering the cellular localization of proteins, affecting proteins activity, and promoting or preventing protein-protein interactions. Deregulation of ubiquitin pathway leads to many diseases such as neurodegeneration, cancer, infection and immunity, etc.

MCE offers a unique collection of 258 small molecule modulators with biological activity used for ubiquitination research. Compounds in this library target the key enzymes in ubiquitin pathway. MCE Ubiquitination Compound Library is a useful tool for the research of ubiquitination regulation and the corresponding diseases.

HY-L081

Phosphatase Inhibitor Library

117 compounds

Protein phosphorylation is a key post-translational modification underlying the regulation of many cellular processes. Phosphatases and kinases contribute to the regulation of protein phosphorylation homeostasis in the cell. This reversible regulation of protein phosphorylation is critical for the proper control of a wide range of cellular activities, including cell cycle, proliferation and differentiation, metabolism, cell-cell interactions, etc.

Protein phosphatases have evolved in separate families that are structurally and mechanistically distinct. Based on substrate specificity and functional diversity, protein phosphatases are classified into two superfamilies: Protein serine/threonine phosphatases and Protein tyrosine phosphatases. Ser/Thr phosphatases are metalloenzymes belonging to two major gene families termed PPP (phosphoprotein phosphatase) and PPM (metal-dependent protein phosphatases), whereas protein tyrosine phosphatases (PTPs) belong to distinct classes of enzymes that utilize a phospho-cysteine enzyme intermediate as a part of their catalytic action.

MCE supplies a unique collection of 117 phosphatase inhibitors that mainly targeting protein tyrosine phosphatases (PTPs) and serine/threonine-specific protein phosphatases. MCE Phosphatase Inhibitor Library is a useful tool for phosphatase drug discovery and related research.

HY-L204

Lactic Acid Metabolic Compound Library

330 compounds

Lactic acid metabolism is one of the key metabolic pathways within living organisms. It plays a crucial role not only in cellular energy conversion but is also closely related to a variety of physiological and pathological processes. The production and clearance of lactic acid are important indicators of cellular metabolic balance, and its abnormal regulation may lead to conditions such as lactic acidosis, muscle fatigue, and hereditary metabolic diseases. Moreover, lactic acid is closely related to the malignancy of tumors and is considered a biomarker for malignant tumors and poor prognosis. Lactic acid can serve as a metabolic substrate to support the metabolic needs of tumor cells under hypoxic conditions, and it can also cause acidification of the tumor microenvironment, suppress immune cell function to promote immune evasion, and induce drug resistance in tumor cells. Currently, targeting lactic acid-lactylation and its related metabolic pathways has become a new research avenue for cancer treatment. In-depth exploration of the molecular mechanisms of lactic acid metabolism can help in screening lead compounds that regulate the lactic acid metabolism.

MCE contains 330 small molecule compounds targeting enzymes involved in lactic acid metabolism. This library is of significant value for researching the role of lactate metabolism in the mechanisms of diseases.

HY-L015

PI3K/Akt/mTOR Compound Library

600 compounds

The PI3K/Akt/mTOR pathway controls many cellular processes that are important for the formation and progression of cancer, including apoptosis, transcription, translation, metabolism, angiogenesis, and cell cycle progression. Every major node of this signaling network is activated in a wide range of human tumors. Mechanisms for the pathway activation include activation of receptor tyrosine kinases (RTKs) upstream of PI3K, mutation or amplification of PIK3CA encoding p110α catalytic subunit of PI3K, mutation or loss of PTEN tumor suppressor gene, and mutation or amplification of Akt1. Once the pathway is activated, signaling through Akt can stimulate a series of substrates including mTOR which is involved in protein synthesis. Thus, inhibition of this pathway is an attractive concept for cancer prevention and/or therapy. Currently some mTOR inhibitors are approved for several indications, and there are several novel PI3K/Akt/mTOR inhibitors in clinical trials.

MCE owns a unique collection of 600 compounds that can be used for PI3K/Akt/mTOR pathway research. PI3K/Akt/mTOR Compound Library also acts as a useful tool for anti-cancer drug discovery.

Cat. No.	Product Name	Type

HY-129096

IDT307	Chromogenic Substrates
IDT307, an analog of the organic cation MPP+, is a specific fluorescent substrate for DAT (fluorescent substrate APP+) .

HY-P3363

Z-DEVD-AMC	Chromogenic Substrates
Z-DEVD-AMC is a selective caspase-3 substrate that can be measured by fluorescence spectrometry. AMC can be used as a fluorescence reference standard for AMC-based enzyme substrates including AMC-based caspase substrates .

HY-D0144

Resorufin methyl ether Methoxyresorufin	Chromogenic Substrates
Resorufin methyl ether (Methoxyresorufin) is a cytochrome P450 fluorometric substrate . Resorufin methyl ether is a relatively specific substrate for CYP1A2 activity in rodents .

HY-D0145

7-Ethoxyresorufin 1 Publications Verification Resorufin ethyl ether	Chromogenic Substrates
7-Ethoxyresorufin (Resorufin ethyl ether) is a fluorometric substrate and competitive inhibitor of cytochrome P450, especially CYP1A1. 7-Ethoxyresorufin also inhibits NO synthase .

HY-D0994

4-Methylumbelliferyl phosphate 4-MUP; MUP	Chromogenic Substrates
4-Methylumbelliferyl phosphate (4-MUP), an anionic organophosphate, is a acid and alkaline phosphatase fluorogenic substrate. 4-Methylumbelliferyl phosphate is also a nerve agent simulant .

HY-P4202

Suc-Ala-Glu-Pro-Phe-pNA Suc-AEPF-pNA	Chromogenic Substrates
Suc-Ala-Glu-Pro-Phe-pNA (Suc-AEPF-pNA) is a chromogenic substrate for the peptidylprolyl isomerase Pin1. Suc-Ala-Glu-Pro-Phe-pNA can be used to evaluate the inhibitory effect of the target compound on Pin1, and catalytic activity of Pin1, etc .

HY-W357142

3-Acetylumbelliferyl β-D-Glucopyranoside	Chromogenic Substrates Fluorescent Dyes/Probes
3-Acetylumbelliferyl β-D-Glucopyranoside is a fluorogenic substrate for β-glucosidase and can be used as a positive control substrates for β-D-glucosidase .

HY-W357151

6-Chloro-3-indoxyl-α-D-mannopyranoside	Chromogenic Substrates
6-Chloro-3-indoxyl-α-D-mannopyranoside is a chromogenic substrate for α-mannosidase resulting in a salmon colored precipitate upon cleavage.

HY-W320032

5-Bromo-1H-indol-3-yl octanoate	Chromogenic Substrates
5-Bromo-1H-indol-3-yl octanoate is a chromogenic substrate for esterase with C8 activity. 5-Bromo-1H-indol-3-yl octanoate yields a blue precipitate when cleaved.

HY-W345102

4-Methylumbelliferyl β-cellotrioside	Chromogenic Substrates
4-Methylumbelliferyl β-cellotrioside, a chromogenic substrate for β-glycosidases, is a cellulose fluorescent derivative .

HY-P4202A

Suc-Ala-Glu-Pro-Phe-pNA TFA Suc-AEPF-pNA TFA	Chromogenic Substrates
Suc-Ala-Glu-Pro-Phe-pNA (Suc-AEPF-pNA ) TFA is a chromogenic substrate for the peptidylprolyl isomerase Pin1. Suc-Ala-Glu-Pro-Phe-pNA TFA can be used to evaluate the inhibitory effect of the target compound on Pin1, and catalytic activity of Pin1, etc .

HY-D1670

Z-Gly-Pro-AMC	Chromogenic Substrates
Z-Gly-Pro-AMC is a fluorogenic substrate. Z-Gly-Pro-AMC is hydrolyzed by prolyl endopeptidase to generate highly fluorescent 7-amido-4-methylcoumarin (HY-D0027). (λ_ex=380 nm, λ_em=465 nm) .

HY-148073

MeO-Succ-Arg-Pro-Tyr-AMC	Chromogenic Substrates
MeO-Succ-Arg-Pro-Tyr-AMC is an analogue of 7-amido-4-methylcoumarin (HY-D0027). MeO-Succ-Arg-Pro-Tyr-AMC is a sensitive fluorescent substrate chymotrypsin-like protease. (λ_ex=341 nm, λ_em=441 nm).

HY-15934

X-GAL 1 Publications Verification BCIG	Chromogenic Substrates
X-GAL (BCIG) is a widely used chromogenic β-galactosidase substrate. X-GAL is a colorless compound until cleaved by β-galactosidase, at which point X-GAL turns to an insoluble and detectable blue compound, making X-GAL particularly useful in techniques such as blue-white screening for cloning in bacteria. X-GAL can also be used for detection of β-galactosidase activity .

HY-W116594

X-GalNAc	Chromogenic Substrates
X-GalNAc is a chromogenic substrate for for N-acetyl-β-galactosidase, used to determine the presence or absence of a cloned DNA insert in bacteria growing on agar plates .

HY-W141825

N-Acetyl-DL-phenylalanine β-naphthyl ester	Chromogenic Substrates
N-Acetyl-DL-phenylalanine β-naphthyl ester is an aromatic amino acid ester, which functions as a chromogenic substrate for chymotrypsin and microbial serine proteases such as subtilisin .

HY-W354821

4-Methylumbelliferyl Decanoate 4-MUD	Chromogenic Substrates Fluorescent Dyes/Probes
4-Methyl-2-oxo-2H-1-benzopyran-7-yl decanoate is a fluorogenic substrate used to follow the hydrolytic activity of carboxylesterases .

HY-W015996

4-Nitrophenyl-N-acetyl-α-D-galactosaminide pNP-GlcNAc	Chromogenic Substrates
4-Nitrophenyl-N-acetyl-α-D-galactosaminide (pNP-GlcNAc) can be used as a chromogenic substrate for N-acetyl-D-galactosaminase. 4-Nitrophenyl-N-acetyl-α-D-galactosaminide is cleaved by N-acetyl-D-galactosaminase to generate a yellow solution. The enzyme activity is quantitatively determined by absorbance detection .

HY-W338079

Ac-Asp-Glu-Val-Asp-pNA	Fluorescent Dyes/Probes
Ac-Asp-Glu-Val-Asp-pNA is a peptidic substrate of caspase-3/7 .

HY-116583

Resorufin butyrate	Fluorescent Dyes/Probes
Resorufin butyrate is a fluorogenic substrate for triglyceride lipases and cholinesterase (Ex=570 nm, Em=580 nm) .

HY-131498

MOCAc-PLGL(Dpa)AR Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2	Fluorescent Dyes/Probes
MOCAc-PLGL(Dpa)AR is a positively charged fluorescent substrate for matrix metalloproteinase-2 (MMP-2), MMP-7 and MMP-9. MOCAc-PLGL(Dpa)AR is a substrate of matrilysin, can be cleaved at the peptide bond between the glycine and leucine residues .

HY-D1461

Fluorescein Di-β-D-Glucopyranoside	Fluorescent Dyes/Probes
Fluorescein Di-β-D-Glucopyranoside is a specific β-glucocerebrosidase substrate that can be used for the intralysosomal β-galactosidase .

HY-P3484

Dnp-PLGLWA-DArg-NH2 TFA	Fluorescent Dyes/Probes
Dnp-PLGLWA-DArg-NH2 TFA is a fluorogenic substrate for MMP-1 and MMP-9. Dnp-PLGLWA-DArg-NH2 TFA can be used to quantify the activity of MMPs (Ex=280 nm, Em=360 nm) .

HY-137928

H-Ala-4MβNA hydrochloride	Fluorescent Dyes/Probes
H-Ala-4MβNA hydrochloride is a specific fluorogenic substrate for aminopeptidase M .

HY-137834

Gly-Pro-AMC hydrobromide 1 Publications Verification	Fluorescent Dyes/Probes
Gly-Pro-AMC hydrobromide is a fluorescent dye, it can be used as a specific fluorescent substrate for detecting Dipeptidyl peptidase IV (DPP-IV) activity .

HY-P2208

Z-IETD-AFC	Fluorescent Dyes/Probes
Z-IETD-AFC, a specific fluorescence substrate, can be used to determine the caspase-8 catalytic activity .

HY-137845

4-Methylumbelliferyl β-D-galactopyranoside 1 Publications Verification	Fluorescent Dyes/Probes
4-Methylumbelliferyl β-D-galactopyranoside is a fluorescent substrate for β-galactosidase which, when cleaved, produces a water-soluble blue fluorescent coumarin fluorophore that can be detected using a fluoroenzymeter or fluorometer .

HY-141575

C12-NBD-ceramide	Fluorescent Dyes/Probes
C12-NBD-ceramide is a fluorescent analogue of ceramide, it can be used as a substrate in ceramidase assays .

HY-134432B

Boc-Gln-Ala-Arg-AMC acetate	Dyes
Boc-Gln-Ala-Arg-AMC acetate is a fluorogenic substrate for trypsin. Boc-Gln-Ala-Arg-AMC acetate can also be used for measuring the proteolytic activity of TMPRSS2 .

HY-113862

PHOME	Dyes
PHOME is a fluorogenic substrate for sEH. sEH can hydrolyze the epoxy ring in the PHOME substrate. PHOME can be used for fluorescent epoxide hydrolase assay (extracted from patent CN113402447A) .

HY-D1705

Ac-ANW-AMC	Fluorescent Dyes/Probes
Ac-ANW-AMC is a fluorogenic substrate for immunoproteasome. Ac-ANW-AMC can be used to measure β5i activity (Ex=345 nm, Em=445 nm) .

HY-P3475

Mca-VDQMDGW-K(Dnp)-NH2	Fluorescent Dyes/Probes
Mca-VDQMDGWK-(Dnp)-NH2 is a fluorogenic substrate for caspase-3 and can be used to quantify caspase-3 activity .

HY-D1634

Bz-FVR-AMC	Chromogenic Substrates
Bz-FVR-AMC is a fluorogenic substrate for procathepsin with a k_cat/K_m value of 1070 mM ^-1s ^-1. The high concentration of BZ-FVR-AMC inhibits the substrate .

HY-D0719

Fluorescein Diacetate 4 Publications Verification 3,6-Diacetoxyfluoran; Di-O-acetylfluorescein	Dyes Enzyme Substrates
Fluorescein diacetate is a cell permeable esterase-substrate. Fluorescein diacetate can be used as a fluorogenic substrate for hGSTP1-1.

HY-D1584

C12 NBD Sphingomyelin	Fluorescent Dyes/Probes
C12 NBD sphingomyelin is an active derivative of sphingomyelin (HY-113498) that is tagged with fluorescent C12 nitrobenzoxadiazole (C12 NBD). C12 NBD sphingomyelin can be used as a sphingomyelinase substrate for studying the metabolism and transport of sphingomyelins (Ex=470 nm, Em=525 nm) .

HY-134435

Z-Arg-AMC hydrochloride	Fluorescent Dyes/Probes
Z-Arg-AMC hydrochloride is a fluorogenic substrate for trypsin and papain. Z-Arg-AMC hydrochloride can be used to research activity of trypsin (Ex/Em=355/460 nm) .

HY-P2065

Ac-VEID-AMC	Fluorescent Dyes/Probes
Ac-VEID-AMC is a fluorescent substrate for the determination of caspase-6 and related cysteine protease activities (Ex=340-360 nm, Em=440-460 nm) .

HY-123051

Ac-WLA-AMC	Fluorescent Dyes/Probes
Ac-WLA-AMC is a specific 20S constitutive proteasome β5 fluorogenic substrate .

HY-D1027

Dansylcadaverine 5+ Cited Publications Monodansyl cadaverine	Fluorescent Dyes/Probes
Dansylcadaverine (Monodansyl cadaverine) is an autofluorescent compound used for the labeling of autophagic vacuoles. Dansylcadaverine, a high affinity substrate of transglutaminases, can block the receptor-mediated endocytosis of many ligands .

HY-15902

ABTS diammonium salt 4 Publications Verification AzBTS-(NH4)2	Chromogenic Substrates
ABTS diammonium salt is a substrate for horseradish peroxidase (HRP) conjugate.

HY-P1448

Ac-Leu-Arg-AMC	Chromogenic Substrates
Ac-Leu-Arg-AMC is a fluorogenic peptide substrate.

HY-15925

Nitro blue tetrazolium chloride 5+ Cited Publications NBT	Chromogenic Substrates
Nitro blue tetrazolium chloride (NBT) is a substrate for dehydrogenases; is used with the alkaline phosphatase substrate 5-Bromo-4-Chloro-3-Indolyl Phosphate (BCIP) in western blotting and immunohistological staining procedures .

HY-P3791

N-Succinyl-Ile-Ile-Trp-AMC	Fluorescent Dyes/Probes
N-Succinyl-Ile-Ile-Trp-AMC is a peptide-based fluorescent substrate or probe for carboxypeptidase Y (CPY) .

HY-P0136AF

FAM-SAMS TFA	Dyes
FAM-SAMS TFA is a 5-FAM (HY-66022) labeled SAMS (HY-P0136). SAMS peptide is a specific substrate for the AMP-activated protein kinase (AMPK) .

HY-136865

MeOSuc-AAPV-AMC	Fluorescent Dyes/Probes
MeOSuc-AAPV-AMC is a fluorogenic substrate for human leukocyte and porcine pancreatic elastase (K_m: 362 μM, Ex=380 nm, Em=460 nm) .

HY-129887

Fluorescein diphosphate tetraammonium	Fluorescent Dyes/Probes
Fluorescein diphosphate tetraammonium is a fluorescent dye, it can be used as a fluorogenic substrate and generats fluorescein as a fluorescent product .

HY-P3362

Ac-IETD-AMC	Fluorescent Dyes/Probes
Ac-IETD-AMC is a fluorogenic caspase-8/granzyme B substrate containing the acetyl (Ac) moiety. Ac-IETD-AMC is frequently used to measure caspase-8 activity .

HY-P1169

Ac-IETD-AFC 1 Publications Verification	Fluorescent Dyes/Probes
Ac-IETD-AFC is a fluorogenic substrate of caspase-8, caspase-3, caspase-10, and granzyme B .

HY-111956

D-Ala-Lys-AMCA	Fluorescent Dyes/Probes
D-Ala-Lys-AMCA is a known proton-coupled oligopeptide transporter 1 (PEPT1) substrate that emits blue fluorescence. D-Ala-Lys-AMCA may be transported into liver cancer cells and Caco-2 cells based on fluorescence analysis. D-Ala-Lys-AMCA can be used for characterizing PEPT1-specific substrates or inhibitors .

HY-111956B

D-Ala-Lys-AMCA hydrochloride 1 Publications Verification	Fluorescent Dyes/Probes
D-Ala-Lys-AMCA hydrochloride is a known proton-coupled oligopeptide transporter 1 (PEPT1) substrate that emits blue fluorescence. D-Ala-Lys-AMCA hydrochloride may be transported into liver cancer cells and Caco-2 cells based on fluorescence analysis. D-Ala-Lys-AMCA hydrochloride can be used for characterizing PEPT1-specific substrates or inhibitors .

Cat. No.	Product Name	Type

HY-112832

Lumigen APS-5	Enzyme Substrates
Lumigen APS-5 is a substrate of alkaline phosphatase (ALP). Lumigen APS-5 can be used to assess the activity of alkaline phosphatase (ALP) .

HY-137841

L-Arginine-7-amido-4-methylcoumarin hydrochloride Arginine 4-methyl-7-coumarylamide hydrochloride	Enzyme Substrates
L-Arginine-7-amido-4-methylcoumarin (Arginine 4-methyl-7-coumarylamide) hydrochloride is a specific substrate of cathepsin H but not for cathepsins L and B .

HY-137840

Hippuryl-L-phenylalanine	Enzyme Substrates
Hippuryl-L-phenylalanine is a substrate of carboxypeptidase. Carboxypeptidase is a protease enzyme that related with obesity, epilepsy and neurodegeneration. Hippuryl-L-phenylalanine can be used for the determination of carboxypeptidase activity .

HY-W039911

4-Nitrophenyl α-D-galactopyranoside PNP-alpha-D-Gal; PNP-α-D-Gal	Enzyme Substrates
4-Nitrophenyl α-D-galactopyranoside (PNP-alpha-D-Gal) is an artificial substrate of 4-nitrophenyl (pNP) glycopyranoside for detecting α-galactosidase activity. The amount of released pNP is significantly increased when 4-Nitrophenyl α-D-galactopyranoside is used as substrates .

HY-116022A

4-Nitrophenyl phosphate disodium hexahydrate 3 Publications Verification p-Nitrophenyl phosphate disodium hexahydrate	Enzyme Substrates
4-Nitrophenyl phosphate (p-nitrophenyl phosphate) disodium hexahydrate is widely used as a small molecule phosphotyrosine-like substrate in activity assays for protein tyrosine phosphatases. 4-Nitrophenyl phosphate disodium hexahydrate is a colorless substrate that upon hydrolysis is converted to a yellow 4-nitrophenolate ion that can be monitored by absorbance at 405 nm .

HY-W017353

Pseudopelletierine	Enzyme Substrates
Pseudopelletierine is an alkaloid compound that can be used as a enzyme substrate .

HY-134420

p-Nitrophenyl α-L-fucoside PNP α-L-Fuc	Enzyme Substrates
p-Nitrophenyl α-L-fucoside (PNP α-L-Fuc) is a substrate for the determination of α-L-fucosidase .

HY-131475

Naphthol AS-BI phosphate	Enzyme Substrates
Naphthol AS-BI phosphate is a substrate for acid and alkaline phosphatase and can be used in fluorescence assays. Naphthol AS-BI phosphate is a kind of biological materials or organic compounds that are widely used in life science research .

HY-W040116

MUF-diNAG 4-Methylumbelliferyl N,N-diacetyl-β-D-chitobioside	Enzyme Substrates
MUF-diNAG (4-Methylumbelliferyl N,N-diacetyl-β-D-chitobioside) can be used as a fluorescent substrate. MUF-diNAG is a kind of biological materials or organic compounds that are widely used in life science research .

HY-134423

Stearoyl coenzyme A lithium Stearoyl-CoA lithium	Enzyme Substrates
Stearoyl coenzyme A (Stearoyl-CoA) lithium is an active compound that can be used as a substrate for the determination of stearoyl-Coenzyme desaturase in microsomes .

HY-137854

Naphthol AS-BI N-acetyl-β-D-glucosaminide	Enzyme Substrates
Naphthol AS-BI N-acetyl-β-D-glucosaminide acts as a substrate and reacts directly with N-acetyl-β-glucosaminidase enzyme. Naphthol AS-BI N-acetyl-β-D-glucosaminide can detect and localize the active region of N-acetyl-β-glucosaminidase enzyme visually .

HY-D0183

ATP-polyamine-biotin 1 Publications Verification	Enzyme Substrates
ATP-polyamine-biotin, the first cell-permeable ATP analogue, is an efficient kinase cosubstrate. ATP-polyamine-biotin promotes biotin labeling of kinase substrates in live cells .

HY-134163

4-Methylumbelliferyl α-L-arabinopyranoside 4-Methylumbelliferyl alpha-L-arabinopyranoside	Carbohydrates
4-Methylumbelliferyl α-L-arabinopyranoside (4-Methylumbelliferyl alpha-L-arabinopyranoside) is a substrate for enzymes that hydrolyze arabinose-containing substrates, such as α-L-arabinopyranoside .

HY-W011654

4-Aminophenyl-β-D-galactopyranoside, 98% 4-Aminophenyl-beta-D-galactopyranoside, 98%	Carbohydrates
4-Aminophenyl-β-D-galactopyranoside, 98% is a biochemical reagent. 4-Aminophenyl-β-D-galactopyranoside, 98% is a substrate for β-galactosidase (HY-P2869) .

HY-P3008

Submandibular mucin	Native Proteins
Submandibular mucin is a high molecular weight glycoprotein that is used as a substrate for the viral enzyme neuraminidase .

HY-W011183

4-Nitrophenyl-N-acetyl-β-D-glucosaminide	Carbohydrates
4-Nitrophenyl-N-acetyl-β-D-glucosaminide, an artificial substrate of N-acetyl-beta-D-hexosaminidase (NAGase), can be used in rapid and accurate rate assay for N-acetyl-beta-D-hexosaminidase .

HY-137942

1-Naphthyl phosphate disodium salt, 98% α-Naphthyl phosphate disodium salt, 98%	Enzyme Substrates
1-Naphthyl phosphate disodium salt, 98% is a histochemical substrate for acidic and alkaline phosphatases, and can also be used as a substrate for measuring prostatic acid phosphatase.

HY-114365

UDP-GalNAc disodium UDP-N-acetyl-D-galactosamine disodium	Gene Sequencing and Synthesis
UDP-GalNAc (UDP-N-acetyl-D-galactosamine) disodium is a sugar nucleotide and a substrate of EpsC115. EpsC115 is an exopolymeric substances (EPS) N-terminal deletion mutant with the residue 1-115 deletion. UDP-GalNAc UDP-GalNAc is the donor substrate of many N-acetylgalactosaminyltransferases, enzymes which transfer GalNAc from the nucleotide sugar to a saccharide or peptide acceptor .

HY-D0719

Fluorescein Diacetate 4 Publications Verification 3,6-Diacetoxyfluoran; Di-O-acetylfluorescein	Dyes Enzyme Substrates
Fluorescein diacetate is a cell permeable esterase-substrate. Fluorescein diacetate can be used as a fluorogenic substrate for hGSTP1-1.

HY-W015451

2,7-Dihydroxynaphthalene 2,7-DHN; Naphthalene-2,7-diol	Biochemical Assay Reagents
2,7-Dihydroxynaphthalene (2,7-DHN; Naphthalene-2,7-diol) is an aromatic substrate by the bacterial ABBA prenyltransferases NphB and SCO7190 .

HY-76253

Benzylamine hydrochloride Phenylmethylamine	Enzyme Substrates
Benzylamine hydrochloride is a substrate for benzylamine oxidase and monoamine oxidase B.

HY-15926

ONPG 4 Publications Verification 2-Nitrophenyl β-D-galactopyranoside	Enzyme Substrates
ONPG is a colorimetric and spectrophotometric substrate for detection of β-galactosidase activity.

HY-W719646

Naphthol AS phosphate, 99%(TLC） 3-Hydroxy-2-naphthanilide phosphate, 99%(TLC）	Enzyme Substrates
Naphthol AS phosphate, 99%(TLC) is a histochemical substrate for acidic and alkaline phosphatases.

HY-W250153

Adenosine 3'-phosphate 5'-phosphosulfate lithium	Biochemical Assay Reagents
Adenosine 3'-phosphate 5'-phosphosulfate lithium is a co-substrate used for the sulfonation of glycans. Adenosine 3'-phosphate 5'-phosphosulfate lithium can be used for Golgi-resident PAP-specific 3'-phosphatase-coupled sulfotransferase assays, which as donor substrate to transfer a sulfonate group .

HY-D0719R

Fluorescein Diacetate (Standard)	Dyes Enzyme Substrates
Fluorescein Diacetate (Standard) is the analytical standard of Fluorescein Diacetate. This product is intended for research and analytical applications. Fluorescein diacetate is a cell permeable esterase-substrate. Fluorescein diacetate can be used as a fluorogenic substrate for hGSTP1-1.

HY-15906

AMPPD Lumi-Phos Plus; Lumigen PPD; PPD	Enzyme Substrates
AMPPD, a 1,2-dioxo-cyclohexane derivative, is a biochemistry ultrasensitive alkaline phosphatase substrate.

HY-137870

γ-Glutamyl-β-naphthylamide gamma-Glutamyl-beta-naphthylamide	Cell Assay Reagents
γ-Glutamyl-β-naphthylamide is a substrate for γ-glutamine peptidase. γ-Glutamyl-β-naphthylamide is specifically recognized and the peptide chain is cleaved. γ-Glutamyl-β-naphthylamide can be used to distinguish between gonococci and meningococci .

HY-134421

2-Butenoyl coenzyme A lithium	Enzyme Substrates
2-Butenoyl coenzyme A (lithium), an active compound, can be used as a substrate for plasmodium falciparum enyl-ACP reductases and other enyl-CoA reductases. 2-Butenoyl coenzyme A lithium can be used as a substrate analogue to study the kinetics of β-hydroxyacyl-acyl-carrier protein (ACP) dehydratase (FabZ) .

HY-137496

4-Methylumbelliferyl β-D-mannopyranoside	Enzyme Substrates
4-Methylumbelliferyl β-D-mannopyranoside is a substrate that exhibits β-mannosidase activity. 4-Methylumbelliferyl β-D-mannopyranoside can be used to study β-mannosidase deficiency. The reactivity of 4-Methylumbelliferyl β-D-mannopyranoside shows different inhibitory effects on various substrates.

HY-15936

γ-GT	Enzyme Substrates
γ-GT(63699-78-5) is a substrate for γ-glutamyl transferase in biochemical test.

HY-D1208

CDP-Star	Chromogenic Substrates
CDP-Star is a chemiluminescent substrate for alkaline phosphatase. CDP-Star can be used for enzyme-linked immunoassays .

HY-134433A

GDP-L-fucose disodium	Carbohydrates
GDP-L-fucose disodium is a nucleotide sugar that is a key substrate for the biosynthesis of fucose oligosaccharides. GDP-L-fucose disodium provides the fucose moiety for the oligosaccharides. The formation of GDP-L-fucose disodium occurs through two pathways, the major de novo metabolic pathway and the minor remedial metabolic pathway .

HY-137895

L-Arginine p-nitroanilide dihydrochloride, 98% H-Arg-pNA 2HCl, 98%	Enzyme Substrates
L-Arginine p-nitroanilide dihydrochloride, 98% (H-Arg-pNA 2HCl, 98%) is a chromogenic substrate for cathepsin H and aminopeptidases.

HY-153101

Gal-G2-CNP	Enzyme Substrates
Gal-G2-CNP, a galactopyranosylmaltoside, can be used as substrate for the determination of novel amylase and pancreatic amylase .

HY-W015451R

2,7-Dihydroxynaphthalene (Standard)	Biochemical Assay Reagents
2,7-Dihydroxynaphthalene (Standard) is the analytical standard of 2,7-Dihydroxynaphthalene. This product is intended for research and analytical applications. 2,7-Dihydroxynaphthalene (2,7-DHN; Naphthalene-2,7-diol) is an aromatic substrate by the bacterial ABBA prenyltransferases NphB and SCO7190 .

HY-15911

CNP-AFU 2-Chloro-4-nitrophenyl α-L-fucopyranoside	Enzyme Substrates
CNP-AFU (2-Chloro-4-nitrophenyl α-L-fucopyranoside) is a substrate for alpha-L-fucosidase(AFU).

HY-147112

MNP-GAL	Enzyme Substrates
MNP-GAL is MNPs coated with galactose. MNP-Gal can be used as substrate for the assay of NAG and beta-d-galactosidase .

HY-134425

β-Methylcrotonyl coenzyme A lithium	Enzyme Substrates
β-Methylcrotonyl coenzyme A lithium is an intermediate in leucine metabolism and can be used as a substrate to study the specificity and kinetics of β-methylcrotonyl coenzyme A carboxylase (MCCase) .

HY-137855

4-Methylumbelliferyl sulfate potassium

Enzyme Substrates

4-Methylumbelliferyl sulfate (potassium), a fluorescent substrate, is commonly used to detect sulfatase activity in biochemical and biomedical research. It consists of a sulfate group attached to a fluorescent molecule, which can be cleaved by sulfatase enzymes. Upon cleavage, 4-Methylumbelliferyl sulfate releases a highly fluorescent product that can be detected using fluorescence microscopy or spectroscopy. The use of 4-Methylumbelliferyl sulfate as a substrate for sulfatase enzymes allows accurate detection and quantification of these enzymes in a variety of biological samples.

HY-131474

Naphthol AS-D chloroacetate，98% (TLC) 3-Hydroxy-2-naphthoic-o-toluidide chloroacetate,98% (TLC)	Enzyme Substrates
Naphthol AS-D chloroacetate, 98% (TLC) (3-Hydroxy-2-naphthoic-o-toluidide chloroacetate, 98% (TLC)) is a substrate for esterase histochemical localization.

HY-E70148

ST6 Gal Sialyltransferase 1 EC:2.4.3.1; ST6GAL1	Enzyme Substrates
ST6 Gal Sialyltransferase 1 (EC:2.4.3.1, ST6GAL1) catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates .

HY-D0904

Acetylthiocholine iodide S-Acetylthiocholine iodide; ATCh iodide	Enzyme Substrates
Acetylthiocholine iodide can be used as a substrate for certain enzymes, such as cholinesterase, etc., and can be used to determine the activity level of these enzymes. In addition, the compound is used in some medical research, for example in the fields of neuroscience and organ physiology.

HY-15927

4-Nitrophenyl β-D-glucopyranoside 1 Publications Verification	Enzyme Substrates
4-Nitrophenyl β-D-glucopyranoside is a chromogenic substrate for β-glucosidase. 4-Nitrophenyl β-D-glucopyranoside can be used to measure of β-glucosidase activity .

HY-154922

Palmitoyl coenzyme A Palmitoyl CoA	Enzyme Substrates
Palmitoyl coenzyme A is an acyl-CoA thioester that can be transported into the mitochondrial matrix via the carnitine shuttle system and is involved in β-oxidation. Palmitoyl coenzyme A can also be used as a substrate for sphingosine biosynthesis .

HY-E70191

β-1,4-Galactosyltransferase 2 EC:2.4.1.22; B4GALT2	Enzyme Substrates
β-1,4-Galactosyltransferase 2 catal exclusive specificity for the donor substrate UDP-galactose and all transfer galactosein a beta1,4 linkage .

HY-167805

D-Glucose 6-phosphate potassium	Enzyme Substrates
D-Glucose 6-phosphate potassium is a biologically active compound that has the activity of being a substrate for glucose-6-phosphate isomerase. D-Glucose 6-phosphate potassium can participate in the sugar metabolism process and promote the production and utilization of energy in cells.

HY-153102

G3-CNP	Enzyme Substrates
G3-CNP is an α-amylase substrate. The absorbance of G3-CNP cleavage product 2-chloro-4-nitrophenol is measured at 405 nm, which can be used to detect enzyme activity .

HY-116022B

4-Nitrophenyl phosphate ditromethamine p-Nitrophenyl phosphate ditromethamine	Enzyme Substrates
4-Nitrophenyl phosphate ditromethamine is an enzyme substrate commonly used in biochemical assays to measure the activity of various phosphatases, including alkaline phosphatase. 4-Nitrophenylphosphate has unique chemical properties that allow it to be hydrolyzed by phosphatases, releasing a yellow product that can be detected spectrophotometrically.

HY-E70149

ST6 Gal Sialyltransferase 2 EC:2.4.3.1; ST6GAL2	Enzyme Substrates
ST6 Gal Sialyltransferase 2 (EC:2.4.3.1, ST6GAL2) catalyzes the transfer of sialic acid from CMP to an oligosaccharide substrate. ST6 Gal Sialyltransferase 2 plays an important role in schizophrenic research .

HY-E70138

β-1,4-Galactosyltransferase 7 EC:2.4.1.133; B4GALT7	Enzyme Substrates
β-1,4-Galactosyltransferase 7 has exclusive specificity for the donor substrate UDP-galactose and all transfer galactose in a β-1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. .

Cat. No.	Product Name	Target	Research Area

HY-P3363

Z-DEVD-AMC	Caspase	Cancer
Z-DEVD-AMC is a selective caspase-3 substrate that can be measured by fluorescence spectrometry. AMC can be used as a fluorescence reference standard for AMC-based enzyme substrates including AMC-based caspase substrates .

HY-P2498A

*Cathepsin D and E FRET Substrate* acetate**	Cathepsin	Cancer
Cathepsin D and E FRET Substrate acetate is a fluorogenic substrate for cathepsins D and E and not for B, H or L. The cleavage occurs at the Phe-Phe amide bond resul. Cathepsin D and E FRET Substrate is a valuable tool for routine assays and for mechanistic studies on cathepsins E and D .

HY-P4202

Suc-Ala-Glu-Pro-Phe-pNA Suc-AEPF-pNA	Biochemical Assay Reagents	Others
Suc-Ala-Glu-Pro-Phe-pNA (Suc-AEPF-pNA) is a chromogenic substrate for the peptidylprolyl isomerase Pin1. Suc-Ala-Glu-Pro-Phe-pNA can be used to evaluate the inhibitory effect of the target compound on Pin1, and catalytic activity of Pin1, etc .

HY-P10620

GGGYK-Biotin	Peptides	Others
GGGYK-Biotin is a substrate peptide designed to study the substrate specificity of Sortase A. GGGYK-Biotin can be used to develop Sortase A variants with different substrate specificities .

HY-P1909

*Casein Kinase Substrates* 3**	Peptides	Cancer
Casein Kinase Substrates 3 is a substrate of casein kinase.

HY-P10064

Akt Substrate	Peptides	Others
Akt Substrate (Akt/SKG substrate) is a 7 amino acid synthetic peptide suitable as a substrate for Akt .

HY-P2498

Cathepsin D and E FRET Substrate	Cathepsin	Others
Cathepsin D and E FRET Substrate is a fluorogenic substrate for cathepsins D and E and not for B, H or L. The cleavage occurs at the Phe-Phe amide bond resul. Cathepsin D and E FRET Substrate is a valuable tool for routine assays and for mechanistic studies on cathepsins E and D .

HY-P2513

Src Optimal Peptide Substrate	Peptides	Others
Src Optimal Peptide Substrate is a highly specific Src substrate. Src Optimal Peptide Substrate can used to measure the Src activity .

HY-P5990

Prostate Specific Antigen Substrate	PSMA	Cancer
Prostate Specific Antigen Substrate is a prostate specific antigen (PSA) fluorescent substrate. Prostate Specific Antigen Substrate can be used for detect enzymatic activity of PSA .

HY-P4202A

Suc-Ala-Glu-Pro-Phe-pNA TFA Suc-AEPF-pNA TFA	Biochemical Assay Reagents	Others
Suc-Ala-Glu-Pro-Phe-pNA (Suc-AEPF-pNA ) TFA is a chromogenic substrate for the peptidylprolyl isomerase Pin1. Suc-Ala-Glu-Pro-Phe-pNA TFA can be used to evaluate the inhibitory effect of the target compound on Pin1, and catalytic activity of Pin1, etc .

HY-P3944

Calmodulin Dependent Protein Kinase Substrate	CaMK	Neurological Disease
Calmodulin Dependent Protein Kinase Substrate is a Ca ²⁺- and calmodulin (CaM)-dependent protein kinase (CaMK) substrate peptide. Calmodulin Dependent Protein Kinase Substrate is a synthetic peptide substrate for protein kinases .

HY-P3943

*Calmodulin Dependent Protein Kinase Substrate* Analog**	CaMK	Neurological Disease
Calmodulin Dependent Protein Kinase Substrate Analog is a Ca ²⁺- and calmodulin (CaM)-dependent protein kinase (CaMK) substrate peptide. Calmodulin Dependent Protein Kinase Substrate Analog is a synthetic peptide substrate for protein kinases .

HY-P5976

Suc-Arg-Pro-Phe-His-Leu-Leu-Val-Tyr-AMC Renin Substrate I	Renin	Others
Suc-Arg-Pro-Phe-His-Leu-Leu-Val-Tyr-AMC (Renin Substrate I) is a renin substrate

HY-P2414

MMP-13 Substrate	MMP	Inflammation/Immunology
MMP-13 Substrate is a substrate of MMP-13. MMP-13 Substrate can be used for the research of osteoarthritis (OA) .

HY-P2414A

*MMP-13 Substrate* TFA**	MMP	Inflammation/Immunology
MMP-13 Substrate TFA is a substrate of MMP-13. MMP-13 Substrate TFA can be used for the research of osteoarthritis (OA) .

HY-P5992

Factor VIIa substrate	Peptides	Others
Factor VIIa substrate is a colorimetric substrate for Factor VIIa, that can be measured by absorbance at 405 nm .

HY-P10043

MMP-1 Substrate	Peptides	Others
MMP-1 Substrate is a matrix metalloproteinase-1 (MMP-1) selective substrate that can be used for the fluorometric determination of MMP-1 enzymatic activity .

HY-P2714

SEVNLDAEFR	Beta-secretase	Neurological Disease
SEVNLDAEFR is a substrate for BACE1 .

HY-P1344

*DAPK Substrate* Peptide**	DAPK	Cancer
DAPK Substrate Peptide is a synthetic peptide substrate for death associated protein kinase (DAPK), with a K_m of 9 μM .

HY-P3815

*Casein Kinase 2 Substrate* Peptide** 1 Publications Verification	Casein Kinase	Others
Casein Kinase 2 Substrate Peptide is a common CK2 substrate peptide. Casein Kinase 2 Substrate Peptide is synthesized with its C-terminus conjugated to 5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid (EDANS). Casein Kinase 2 Substrate Peptide can be used for protein kinase CK2 activity determination .

HY-P1344A

*DAPK Substrate* Peptide TFA**	DAPK	Cancer
DAPK Substrate Peptide TFA is a synthetic peptide substrate for death associated protein kinase (DAPK), with a K_m of 9 μM .

HY-P10191

*β-Secretase Substrate-1, Fluorogenic*	Peptides	Others
β-Secretase Substrate-1, Fluorogenic is a fluorogenic substrate of β-Secretase that can be used to test β-Secretase activity .

HY-P10042

S6K Substrate	Peptides	Others
S6K Substrate is a substrate for active protein kinases, including CLK2, MRCKalpha, MRCKbeta, p70S6K, ROCK1, ROCK2, RSK1, RSK3, PIM1 .

HY-134445

N-Benzoyl-L-tyrosine p-nitroanilide Bz-Try-pNA	Ser/Thr Protease	Others
N-Benzoyl-L-tyrosine p-nitroanilide is a chymotrypsin substrate .

HY-P10003A

iso-VQA-ACC TFA	Proteasome	Others
iso-VQA-ACC TFA is a constitutive proteasome substrate .

HY-P3949

*Fluorescent Substrate* for Glu-Specific Proteases**	Fluorescent Dye	Others
Fluorescent Substrate for Glu-Specific Proteases is a V8 protease-Specific chromogenic substrate .

HY-P10143

MMP-2/MMP-9 Substrate	Peptides	Others
MMP-2/MMP-9 Substrate, a synthetic colorimetric substrate, is a peptide .

HY-P10059

Boc-Val-Gly-Arg-βNA	Peptides	Others
Boc-Val-Gly-Arg-βNA is a colorimetric substrate for plasminogen activator .

HY-P2179

*MMP-1/MMP-9 Substrate, Fluorogenic*	Fluorescent Dye MMP	Others
MMP-1/MMP-9 Substrate, Fluorogenic is a fluorogenic substrate for MMP-1 and MMP-9 .Ex/Em = 340/440 nm

HY-P10050

Calpain substrate	Peptides	Others
Calpain substrate is the membrane non-permeable fluorogenic calpain substrate and can be used in Calpain enzymatic activity assay .

HY-P3934

*HIV Protease Substrate* I**	HIV Protease	Infection
HIV Protease Substrate I is a chromogenic substrate of HIV-1 protease. HIV Protease Substrate I has the cleavage site of HIV protease .

HY-136626

Z-Ala-Ala-Asn-AMC 3 Publications Verification Cbz-Ala-Ala-Asn-AMC	Fluorescent Dye	Cancer
Z-Ala-Ala-Asn-AMC (Cbz-Ala-Ala-Asn-AMC) is the legumain substrate. Overexpressed legumain in 293 HEK-Leg cells potently cleaved CBZ-Ala-Ala-Asn-AMC .

HY-P3921

Casein Kinase II Substrate	Casein Kinase	Cancer
Casein Kinase II Substrate is a casein kinase II (CK2) peptide substrate that can be selectively phosphorylated by CK2 .

HY-P4498

Z-Ala-Pro-pNA	Peptides	Others
Z-Ala-Pro-pNA is an endopeptidase substrate and can be used to detect the activity of this enzyme .

HY-P10002A

EWFW-ACC TFA	Biochemical Assay Reagents	Others
EWFW-ACC TFA is a specific immunoproteasome substrate that can be used to study immunoproteasome function .

HY-P10044

IGF1Rtide	Peptides	Others
IGF1Rtide can be used as a RET kinase substrate for RET kinase assays .

HY-P10189

*α-Secretase Substrate, Fluorogenic*	Peptides	Others
α-Secretase Substrate, Fluorogenic is α-secretase fluorogenic substrate that can be used to test α-secretase activity .

HY-P10073

*Calpain-1 substrate, fluorogenic*	Fluorescent Dye	Others
Calpain-1 substrate, fluorogenic serves as a sensitive and specific substrate for calpain-1 that cleaves Tyr-Gly bond and results in enhanced fluorescence .(Ex/Em = 490 nm/518 nm)

HY-137186

Suc-Gly-Gly-Phe-pNA	Proteasome	Others
Suc-Gly-Gly-Phe-pNA is the chymotrypsin substrate with an K_m value of 1.6 mM .

HY-P4496

Tos-Gly-Pro-Lys-pNA	Peptides	Others
Tos-Gly-Pro-Lys-pNA is a substrate for the serine protease ALP and can be used to measure the activity of this enzyme .

HY-134434

Z-Arg-Arg-AMC hydrochloride	Cathepsin	Others
Z-Arg-Arg-AMC hydrochloride is a selective substrate of cathepsin B .

HY-P4018

*HIV Protease Substrate* IV**	HIV Protease	Infection
HIV Protease Substrate IV is a substrate of HIV protease. HIV Protease Substrate IV can be used to measure the activity of HIV (human immunodeficiency virus) -1 protease .

HY-P10163

*α-Secretase Substrate* II, Fluorogenic**	Fluorescent Dye	Others
α-Secretase Substrate II, Fluorogenic is an internally quenched fluorogenic peptide substrate for α-Secretase that contains the α-secretase cleavage site of β-Amyloid precursor protein (APP) .Ex/Em = 340/490 nm

HY-P10145

Ac-LEVD-pNA	Peptides	Others
Ac-LEVD-pNA is a chromogenic substrate for caspase-4 and can be used to detect caspase-4 activity .

HY-P4366

Tos-Gly-Pro-Lys-AMC	Ser/Thr Protease	Others
Tos-Gly-Pro-Lys-AMC is a fluorogenic peptide substrate of tryptase .

HY-W719799

Suc-Ala-Leu-Pro-Phe-AMC	Fluorescent Dye	Others
Suc-Ala-Leu-Pro-Phe-AMC is a PPIase fluorogenic substrate .

HY-P3948

*Fluorescent Substrate* for Pro-Specific Proteases**	Fluorescent Dye	Others
Fluorescent Substrate for Pro-Specific Proteases is a fluorescent substrate of pro-specific proteases. Fluorescent Substrate for Pro-Specific Proteases can be used to detect the hydrolysis rate and activity of target enzyme .

HY-P4491

Suc-Leu-Leu-Val-Tyr-pNA	Peptides	Others
Suc-Leu-Leu-Val-Tyr-pNA is a chymotrypsin-like chromogenic substrate that can be used to detect chymotrypsin enzymatic activity .

HY-P4520

(Trp4)-Kemptide	Peptides	Others
(Trp4)-Kemptide is a peptide substrate for adenosine 3',5'-cyclic monophosphate-dependent protein kinase .

HY-126785

Suc-AAP-Abu-pNA Colorimetric Elastase Substrate	Elastase	Others
Suc-AAP-Abu-pNA (Colorimetric Elastase Substrate) is a specific substrate for pancreatic elastase (K_m = 100 μM; K_cat/K_m = 35,300 s ^-1 M ^-1 for rat pancreatic elastase; K_m = 30 μM; K_cat/K_m = 351,000 s ^-1 M ^-1 for porcine pancreatic elastase). Suc-AAP-Abu-pNA also promotes OPC migration .

Cat. No.	Product Name

HY-KE7067

Lambda DNA
Lambda DNA (λ DNA) is the DNA in λ bacteriophage, which is used as the substrate of restriction endonuclease. This product is methylated Lambda DNA.

HY-K1005

Ultra High Sensitivity ECL Kit 70+ Cited Publications
MCE Ultra High Sensitivity ECL Kit is an ultra-sensitive, luminol-based enhanced chemiluminescent substrate for detecting horseradish peroxidase (HRP) labeled antibodies on western blots.

HY-K1088

VF 488 Caspase 3 Assay Kit for Live Cells
MCE VF 488 Caspase 3 Assay Kit for Live Cells uses a fluorescent substrate with cell membrane permeability to detect Caspase 3 activity in live cells.

HY-KE7051

Bsa I, ADCF
Bsa I, ADCF is animal derived component free, and has good redundancy of enzyme activity, which can easily cope with excessive substrate or difficult template enzyme cutting.

HY-KE7054

Xba I, ADCF
Xba I, ADCF is animal derived component free, and has good redundancy of enzyme activity, which can easily cope with excessive substrate or difficult template enzyme cutting.

HY-KE7053

EcoR I, ADCF
EcoR I, ADCF is animal derived component free, and has good redundancy of enzyme activity, which can easily cope with excessive substrate or difficult template enzyme cutting. Isoschizomers: Fun II.

HY-KE7052

BsmB I, ADCF
BsmB I, ADCF is animal derived component free, and has good redundancy of enzyme activity, which can easily cope with excessive substrate or difficult template enzyme cutting. Isoschizomers: Esp3 I, BstGZ53 I, Esp16 I, Esp23 I.

HY-K1107

*DAB Peroxidase Substrate* Kit (Purple-Blue Color)**
MCE DAB Peroxidase Substrate Kit (Purple-Blue Color) can be used for staining and color development detection in experiments such as immunohistochemistry of cells or tissues, in situ hybridization, Western blotting, and for visualizing endogenous HRP in cells or tissues.

Cat. No.	Product Name	Target	Research Area

HY-P990091

Riliprubart SAR 445088	Complement System	Inflammation/Immunology
Riliprubart (SAR445088) is an anti-C1s humanized monoclonal antibody that inhibits activated C1s in the proximal portion of the classical complement system. Riliprubart selectively inhibits activated C1s and prevents the enzymatic action of C1 on its substrates C4 and C2, thus inhibiting the formation of the classical pathway C3 convertase, C4b2a .

Cat. No.	Product Name		Classification

HY-139162

BGN3		Azide
BGN3 is a good substrate for the SNAP-tag ^? and H ⁵ enzymes. The activities of SNAP-tag ^? and H ⁵ enzymes on BGN3 are reasonable (IC₅₀= 15.6 and 23.5 μM, respectively) . BGN3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-139163

BGSN3		Azide
BGSN3 is a good substrate for the SNAP-tag ^? and H ⁵ enzymes. The activities of SNAP-tag ^? and H ⁵ enzymes on BGSN3 are reasonable (IC₅₀=17.8 and 10 μM, respectively) . BGSN3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-131442

Alkyne-phenol 1 Publications Verification Alkyne tyramide; Alk-Ph		Labeling and Fluorescence Imaging Alkynes
Alkyne-phenol (Alk-Ph) is a clickable ascorbate peroxidase 2 (APEX2) probe. Alkyne-phenol substantially improves APEX-labeling efficiency in intact yeast cells, as it is more cell wall-permeant than APEX2 substrate biotin-phenol (BP). Alkyne-phenol also facilitates the identification of APEX-labeling sites, allowing the unambiguous assignment of membrane topology of mitochondrial proteins . Alkyne-phenol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-145934A

UDP-GlcNAz disodium		Azide
UDP-GlcNAz disodium is a substrate for UDP-GlcNAc:polypeptidyltransferase . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-10446

Pralatrexate 5+ Cited Publications		Alkynes
Pralatrexate is an antifolate and is a potent dihydrofolate reductasean (DHFR) inhibitor with a K_i of 13.4 pM. Pralatrexate is a substrate for folylpolyglutamate synthetase with improved cellular uptake and retention. Pralatrexate has antitumor activities and has the potential for relapsed/refractory T-cell lymphoma treatment . Pralatrexate is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-145934

UDP-GalNAz disodium UDP-N-azidoacetylgalactosamine disodium		Azide
UDP-GalNAz disodium (UDP-N-azidoacetylgalactosamine disodium) is the analogue of UDP-GalNAc. UDP-GalNAc is the donor substrate of many N-acetylgalactosaminyltransferases, enzymes which transfer GalNAc from the nucleotide sugar to a saccharide or peptide acceptor . UDP-GalNAz (disodium) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-151655

11-Azidoundecanoic acid		Azide
11-Azidoundecanoic acid is a click chemistry reagent containing an azide group. 11-Azidoundecanoic acid acts as a hydrophobic bioconjugation linker that can be further modified at the azido-position using Staudinger ligation or Click-chemistry. 11-Azidoundecanoic acid is substrate of lipoic acid ligase (LpIA) for labeling . 11-Azidoundecanoic acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-W027544S1

(7-Methoxy-2-oxo-2H-chromen-4-yl)-acetic acid-d6 5-(Dimethyl-d6-amino)-N-(prop-2-ynyl)naphthalene-1-sulfonamide		Alkynes
(7-Methoxy-2-oxo-2H-chromen-4-yl)-acetic acid-d₆ is the deuterium labeled MCA[1]. MCA is a coumarin derivative. MCA quantitates platelet-activating factor by high-performance liquid chromatography with fluorescent detection. MCA can modify FRET peptide substrates for analyzing protease activities[2][3]. (7-Methoxy-2-oxo-2H-chromen-4-yl)-acetic acid-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Cat. No.	Product Name		Classification

HY-134103A

ddGTP trisodium 2′,3′-Dideoxyguanosine 5′-triphosphate trisodium		Nucleotides and their Analogs
ddGTP (2′,3′-Dideoxyguanosine 5′-triphosphate) trisodium is one of 2',3'-dideoxyribonucleoside 5'-triphosphates (ddNTPs) that acts as chain-elongating inhibitor of DNA polymerase for DNA sequencing. ddGTP trisodium acts as an inhibitor or a substrate for DNA polymerase α .

HY-B1465

1-Hexadecanol Palmityl alcohol		Emulsifiers Surfactants
1-Hexadecanol is a fatty alcohol, a lipophilic substrate. 1-Hexadecanol can be used for the research of ferroptosis .

HY-W013706

Inosine-5'-triphosphate trisodium salt		Nucleotides and their Analogs
Inosine-5'-triphosphate trisodium salt is a nucleoside triphosphate and functions as an substrate for ATPases and GTPases .

HY-136648A

2'-Deoxyadenosine-5'-triphosphate trisodium dATP trisodium		Nucleotides and their Analogs
2'-Deoxyadenosine-5'-triphosphate trisodium (dATP trisodium) is a nucleotide used in cells for DNA synthesis (or replication), as a substrate of DNA polymerase .

HY-W013093

Uridine triphosphate trisodium salt 2 Publications Verification UTP trisodium salt; Uridine 5'-triphosphate trisodium salt		Nucleotides and their Analogs
Uridine triphosphate (UTP) trisodium salt is a pyrimidine nucleoside triphosphate that is used as a substrate to synthesize RNA or as an energy source in metabolic reactions. Uridine triphosphate trisodium salt activates membrane-bound P2Y2 receptors .

HY-153479

Aganirsen		Antisense Oligonucleotides
Aganirsen is a 25 mer DNA antisense oligonucleotide, which silences expression of insulin receptor substrate-1 (IRS-1).

HY-153479A

Aganirsen sodium		Antisense Oligonucleotides
Aganirsen sodium is a 25 mer DNA antisense oligonucleotide, which silences expression of insulin receptor substrate-1 (IRS-1).

HY-136648

2'-Deoxyadenosine-5'-triphosphate dATP		Nucleotides and their Analogs
2'-Deoxyadenosine-5'-triphosphate (dATP) is a nucleotide used in cells for DNA synthesis (or replication), as a substrate of DNA polymerase .

HY-107372

Uridine triphosphate UTP; Uridine 5'-triphosphate		Nucleotides and their Analogs
Uridine triphosphate (UTP) is a pyrimidine nucleoside triphosphate that is used as a substrate to synthesize RNA or as an energy source in metabolic reactions. Uridine triphosphate activates membrane-bound P2Y2 receptors .

HY-139101

Guanosine 5'-triphosphate-5'-adenosine GpppA		Cap Analogs
Guanosine 5'-triphosphate-5'-adenosine (GpppA), a 5′ cap analog, can be used for RNA synthesis in vitro. Guanosine 5'-triphosphate-5'-adenosine is a fluorescent substrate analog .

HY-B0351

Taurine 5+ Cited Publications 2-Aminoethanesulfonic acid		Cosolvents pH Modifiers
Taurine, a sulphur-containing amino acid and an organic osmolyte involved in cell volume regulation, provides a substrate for the formation of bile salts, and plays a role in the modulation of intracellular free calcium concentration. Taurine has the ability to activate autophagy in adipocytes .

HY-139101A

Guanosine 5'-triphosphate-5'-adenosine triammonium GpppA triammonium		Cap Analogs
Guanosine 5'-triphosphate-5'-adenosine (GpppA) triammonium, a 5′ cap analog, can be used for RNA synthesis in vitro. Guanosine 5'-triphosphate-5'-adenosine triammonium is a fluorescent substrate analog .

HY-W011834

2'-O-Methylcytidine		Nucleosides and their Analogs
2'-O-Methylcytidine is a 2'-substituted nucleoside as a inhibitor of HCV replication. 2'-O-Methylcytidine inhibits RNA-dependent RNA polymerase (NS5B)-catalyzed RNA synthesis in vitro, in a manner that is competitive with substrate nucleoside triphosphate .

HY-W353804

2′-Deoxy-β-L-uridine		Nucleosides and their Analogs
2'-Deoxy-β-L-uridine is a nucledside analogue and a specific substrate for the viral enzyme, shows no stereospecificity against herpes simplex 1 (HSV1) thymidine kinase (TK). 2′-Deoxy-β-L-uridine exerts antiviral activity via the interation of 5'-triphosphates with the viral DNA polymerase .

HY-N0455

L-Arginine Maximum Cited Publications 8 Publications Verification		Solubilizing Agents
L-Arginine ((S)-(+)-Arginine) is the substrate for the endothelial nitric oxide synthase (eNOS) to generate NO. L-Arginine is transported into vascular smooth muscle cells by the cationic amino acid transporter family of proteins where it is metabolized to nitric oxide (NO), polyamines, or L-proline. L-Arginine is a potent vasodilator, and can be used to induce experimental acute pancreatitis .

HY-126437A

Poly-L-lysine hydrochloride		Polymers
Poly-L-lysine hydrochloride is a nonspecific attachment factor for cells useful in promoting cell adhesion to solid substrates by enhancing electrostatic interaction between negatively charged ions of the cell membrane and the culture surface. Poly-L-lysine hydrochloride is a strong-attraction regulator that promotes liquid-liquid phase separation (LLPS) at low concentrations but suppresses LLPS at high concentrations. Antibacterial cationic peptide. .