2. Search Result
Search Result
Results for "

probe

" in MedChemExpress (MCE) Product Catalog:

2101

Inhibitors & Agonists

7

Screening Libraries

1543

Fluorescent Dye

125

Biochemical Assay Reagents

47

Peptides

6

MCE Kits

1

Inhibitory Antibodies

23

Natural
Products

3

Recombinant Proteins

9

Isotope-Labeled Compounds

197

Click Chemistry

11

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-136404
    Melanin probe-1

    		Others Cancer
    Melanin probe-1 is an 18F-picolinamides based PET probe. Melanin probe-1 can be used for PET imaging of malignant melanoma. Melanin probe-1 exhibits high tumor targeting efficiency, excellent tumor imaging contrasts, desirable biodistribution patterns, and good in vivo stability .
    Melanin probe-1
  • HY-147652
    G-quadruplex DNA fluorescence probe 1

    		DNA Stain Others
    G-quadruplex DNA fluorescence probe 1 (Compound E1) is a selective G-quadruplex DNA targeting fluorescent probe. G-quadruplex DNA fluorescence probe 1 can pass through membrane and enter living cells with low cytotoxicity .
    G-quadruplex DNA fluorescence probe 1
  • HY-D2315
    Probe-Cys

    		Fluorescent Dye Cancer
    Probe-Cys is a water-soluble and selective near-infrared fluorescent probe for Cys (λex= 680 nm, λem=710 nm) that is not interfered by Hcy, GSH, and HS-. Probe-Cys can react with the stimulant 1,4-dimercaptothreitol (DTT) and the inhibitor N-ethylmaleimide (NEM) in HepG2 cells and zebrafish for the detection of endogenous Cys. Probe-Cys can also be used for imaging Cys in Arabidopsis thaliana. Probe-Cys provides a method for cancer diagnosis and exploration of plant sulfur metabolism .
    Probe-Cys
  • HY-D1188
    PARP7-probe-1

    		PARP Cancer
    PARP7-probe-1 is a chemiluminescent labeled PARP7 probe. PARP7-probe-1 is a biotinylated probe binding to the PARP7 active site. PARP7-probe-1 can be used for the research of PARP7 function .
    PARP7-probe-1
  • HY-D1478
    Fluorescent polyamine probe-1

    		Fluorescent Dye Others
    Fluorescent polyamine probe-1 (compound 15) is a linear polyamine probe with high uptake efficiency. Fluorescent polyamine probe-1 can be used for the research of transport system into cancer cells .
    Fluorescent polyamine probe-1
  • HY-D2280
    Estrogen receptor β/HDAC probe 1

    		HDAC Estrogen Receptor/ERR Others
    Estrogen receptor β/HDAC probe 1 (compound P1) is a near-infrared fluorescent probe that dual-targets the estrogen receptor (Estrogen Receptor/ERR) β/histone deacetylase HDAC .
    Estrogen receptor β/HDAC probe 1
  • HY-136219
    Protein kinase affinity probe 1

    		Others Others
    Protein kinase affinity probe 1 is a novel protein kinase affinity probe for the functional identification of protein kinases (PKs). Protein kinase affinity probe 1 is a modified Purvalanol B (HY-18299) probe with 50% beads loading (Compound S3) .
    Protein kinase affinity probe 1
  • HY-D2342
    SARS-CoV-2 3CLpro probe-1

    		Fluorescent Dye Infection
    SARS-CoV-2 3CLpro probe-1 (Compound probe 3) is a selective and activity-based probe for the SARS-CoV-2 3CL protease. SARS-CoV-2 3CLpro probe-1 can detect endogenously expressed 3CLpro in SARS-CoV-2-infected cells .
    SARS-CoV-2 3CLpro probe-1
  • HY-D2327
    DPP-8/9 probe-1

    		Dipeptidyl Peptidase Others
    DPP-8/9 probe-1 (compound 20) is a fluorescent probe targeting Dipeptidyl Peptidase DPP8/9, which can be selectively labeled and visualized in vitro by fluorescence microscopy Active DPP8/9. DPP-8/9 probe-1 contains a nitrobenzoxadiazole (NBD) tag and has high affinity and selectivity for DPP8/9 over related S9 family members (IC50 of 210 nM and 15 nM, respectively) .
    DPP-8/9 probe-1
  • HY-142521
    BLT2 probe 1

    		Leukotriene Receptor Metabolic Disease
    BLT2 probe 1 (compound 13) is a fluorescent probe based on the synthetic BLT2 agonist CAY10583. BLT2 is a promising target for diabetic wound healing and gastrointestinal lesions. BLT2 probe 1 is suitable to investigate the pharmacology of BLT2 receptor ligands in a variety of assay systems .
    BLT2 probe 1
  • HY-145837
    Y1R probe-1

    		Neuropeptide Y Receptor Cancer
    Y1R probe-1 (Compound 39) is a high-affinity fluorescence probe for the Neuropeptide Y Y1 Receptor. Y1R probe-1 has the potential for the research of cancer disease .
    Y1R probe-1
  • HY-135641
    Biotin-probe 1

    		Fluorescent Dye Others
    Biotin-probe 1 is a non-radiolabeled probe. Biotin-labeled probes can be applied to in situ hybridization .
    Biotin-probe 1
  • HY-135640
    TAMRA-probe 1

    		Fluorescent Dye Others
    TAMRA-probe 1 is a commonly used fluorescent probe for labeling .
    TAMRA-probe 1
  • HY-135136
    Aldehyde reactive probe TFA

    		Biochemical Assay Reagents Others
    Aldehyde reactive probe (TFA) is a biotinylated reagent for the detection and quantification of AP sites in damaged DNA .
    Aldehyde reactive probe TFA
  • HY-135639
    Alkyne-probe 1

    		Fluorescent Dye Others
    Alkyne-probe 1 is usually used as a Alkyne-labeled chemical or fluorescent probe. Alkyne-probe 1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Alkyne-probe 1
  • HY-D2331
    ZL-12A probe

    		Fluorescent Dye Others
    ZL-12A probe is a "stereoprobe "that can promote the degradation of TFIIH helicase ERCC3. ZL-12A degrades ERCC3 by covalently modifying C342 .
    ZL-12A probe
  • HY-D2254
    CTB probe-1

    		Fluorescent Dye Others
    CTB probe-1 (probe 1) a lysosome-targeting fluorogenic small-molecule probe for fluorescence imaging in living cells .
    CTB probe-1
  • HY-D2316
    Flipper-TR probe

    		Fluorescent Dye Others
    Flipper-TR probe (Compound FliptR probe) is a fluorescent probe specifically designed to measure cell membrane tension. Flipper-TR probe reports changes in membrane tension through variations in its fluorescence lifetime. Flipper-TR probe is applicable to a wide range of organisms including bacteria, yeast, mammals, and plants .
    Flipper-TR probe
  • HY-136870
    Kyoto probe 1

    		Fluorescent Dye Others
    Kyoto probe 1 is a hiPSCs fluorescent probe. Kyoto probe 1 selectively labels human pluripotent stem cells. Kyoto probe 1 is primarily explained by the distinct expression patterns of ATP-binding cassette (ABC) transporters by hiPS cells and differentiated cells .
    Kyoto probe 1
  • HY-D1397
    Kbz probe 1

    		Fluorescent Dye Others
    Kbz probe 1 serves as a versatile probe for interrogating histone benzoylation and interactions in living cells.
    Kbz probe 1
  • HY-D2380
    H2S probe 1

    		G-quadruplex Cancer
    H2S probe 1 (compound 1NND) is a derivative of nitrobenzoxadiazole (NBD) with antitumor activity. H2S probe 1 is cytotoxic to human pancreatic cancer cell MIA PaCa-2 (IC50=77.9 nM) and has a high affinity for human telomeric G-quadruplex (G4) (Kd=1.72 μM). H2S probe 1 can be used in cancer research .
    H2S probe 1
  • HY-163140
    IL-33 probe-1

    		Interleukin Related Inflammation/Immunology
    IL-33 probe-1 is a fluorescent analogue of the interleukin IL-33[1].
    IL-33 probe-1
  • HY-158779
    Sulfane sulfur probe 4

    SSP4

    		 Fluorescent Dye Others
    Sulfane sulfur probe 4 (SSP4) is a fluorescent probe used to detect sulfane sulfur species (Ex/Em=494/515 nm). Sulfane sulfur probe 4 exhibits high sensitivity in detecting sulfane sulfur, even in the presence of other substances such as homocysteine, methionine, cysteine, glutathione, N-acetyl-L-cysteine, glycine, tyrosine, tryptophan, arginine, and metal ions (Fe 2+, Fe 3+, Mg 2+, Ca 2+, and Zn 2+) .
    Sulfane sulfur probe 4
  • HY-147532
    CB2R probe 1

    		Cannabinoid Receptor Cancer
    CB2R probe 1 is a safe and green CB2R (cannabinoid 2 receptor) fluorescent probe with an Ki of 130 nM. CB2R probe 1 shows low cytotoxicity in cancer cells .
    CB2R probe 1
  • HY-D1377
    Citrulline-specific probe-rhodamine hydrate

    		Fluorescent Dye Others
    Citrulline-specific probe-rhodamine hydrate is a specific probe for citrulline (Citrulline) combined with a rhodamine fluorescent group. Citrulline is the hydrolysis product of arginine catalyzed by protein arginine deiminase (PAD). PAD is abnormally activated in many diseases, leading to increased citrulline levels. Citrulline-specific probe-rhodamine hydrate is a biological probe that can identify diseases showing abnormal increases in PAD activity and may be effectively used in animal models of ulcerative colitis .
    Citrulline-specific probe-rhodamine hydrate
  • HY-136405
    Melanin probe-2

    		Others Others
    Melanin probe-2 (compound 5) is a non-radioactive bromopicolinamide precursor. Melanin probe-2 can be used for 18F-Labeled Picolinamide PET probe synthesis (HY-136404) .
    Melanin probe-2
  • HY-D1399
    Kdn probe-1

    		Fluorescent Dye Others
    Kdn probe-1 is a fluorescent Kdn probe and reveals the localization of AfS in vesicles at the cell surface.
    Kdn probe-1
  • HY-135235
    Cysteine thiol probe

    		Others Others
    Cysteine Thiol Probe is a thiol-based probe designed to label electrophilic natural products. Cysteine Thiol Probe possesses each of the characteristics of an ideal pharmacophore probe, and has a chromophore. Cysteine Thiol Probe is capable of engaging enone-, β-lactam-, and β-lactone-based electrophilic metabolites .
    Cysteine thiol probe
  • HY-D1286
    Serum CG probe 1

    		Fluorescent Dye Inflammation/Immunology
    Serum CG probe 1 (formula (9)) is a compound for determining serum cholyglycine .
    Serum CG probe 1
  • HY-D1287
    Serum CG probe 2

    		Fluorescent Dye Inflammation/Immunology
    Serum CG probe 2 (formula (15)) is a compound for determining serum cholyglycine .
    Serum CG probe 2
  • HY-D1412
    LPd peroxida probe
    1 Publications Verification

    		 Ferroptosis Others
    LPd peroxida probe, a marker of ferroptosis, is a useful fluorescent probe for investigating the roles of lipid peroxidation in a variety of cell pathophysiologies. LPd peroxida probe reduces lipid hydroperoxides to lipid alcohols and is used for imaging lipid hydroperoxides in living cells .
    LPd peroxida probe
  • HY-D1244
    CO probe 1

    		Fluorescent Dye Others
    CO probe 1 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
    CO probe 1
  • HY-D2311
    CDK19 Probe 1

    		CDK Cancer
    CDK19 Probe 1 (Compound 10c) is a CDK19 inhibitor (IC50: 1.01 μM) and can be used for cancer research .
    CDK19 Probe 1
  • HY-143678
    Citrulline-specific probe-biotin

    		Biochemical Assay Reagents Others
    Citrulline-specific probe-biotin is a biotinylated probe for detection of citrulline. Citrulline is the hydrolysis product of arginine catalyzed by protein arginine deiminase (PAD). PAD is abnormally activated in many diseases, leading to increased citrulline levels. Citrulline-specific probe-biotin is a biological probe that can identify diseases showing abnormal increases in PAD activity and may be effectively used in animal models of ulcerative colitis .
    Citrulline-specific probe-biotin
  • HY-D2310
    CXCR2 Probe 1

    		CXCR Inflammation/Immunology
    CXCR2 Probe 1 (Compound [18F]16b) is a selective ligand for CXCR2 and is a radiotracer for PET imaging of neutrophils in inflammatory diseases .
    CXCR2 Probe 1
  • HY-163146
    TME-HYM (PH Probe)

    		Fluorescent Dye Cancer
    TME-HYM (PH Probe) is a novel fluorescent probe based on acidic tumor microenvironment (TME) activation and organic anion transporting polypeptide (OATPs, overexpressed on cancer cells), and can be selective uptaken. TME-HYM (PH Probe) can selectively lit up cancer cells and tumor tissues, offering dual tumor selectivity for precise visualization of tumor mass .
    TME-HYM (PH Probe)
  • HY-P5909
    Keap1-Nrf2 probe

    		Keap1-Nrf2 Cancer
    Keap1-Nrf2 probe is a Keap1-Nrf2 probe .
    Keap1-Nrf2 probe
  • HY-D1302
    Near-IR fluorescent probe-1

    		Fluorescent Dye Others
    Near-IR fluorescent probe-1 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
    Near-IR fluorescent probe-1
  • HY-157916
    ARP

    Aldehyde reactive probe

    		 Fluorescent Dye Others
    ARP (Aldehyde reactive probe) is an aldehyde reactive probe for detecting abasic site (common DNA lesions and intermediates in mutagenesis and carcinogenesis) in DNA, which specificially tags AP site with biotin residues. ARP is highly sensitive with a femtomolar-level basic site detection capabilities (less than one site per 10 4 nucleotides) .
    ARP
  • HY-P5909F
    FITC-labelled Keap1-Nrf2 probe

    		Keap1-Nrf2 Others
    FITC-labelled Keap1-Nrf2 probe is aFITC-labeled Keap1-Nrf2 probe (HY-P5909).
    FITC-labelled Keap1-Nrf2 probe
  • HY-D1458
    Peroxyfluor 1

    		Fluorescent Dye Cardiovascular Disease Neurological Disease Cancer
    Peroxyfluor 1 is a cell-permeable probe for H2O2. Peroxyfluor 1 represents a first-generation, green-fluorescent probe .
    Peroxyfluor 1
  • HY-138760
    SEluc-2

    		Fluorescent Dye Others
    SEluc-2 is a small-molecule probe based on the firefly luciferin. SEluc-2, a bioluminescent probe for the sensitive and selective detection of thiols in living cells .
    SEluc-2
  • HY-W040681
    7-Dimethylaminocoumarin-4-acetic acid

    		Fluorescent Dye Others
    7-Dimethylaminocoumarin-4-acetic acid is a fluorescent probe .
    7-Dimethylaminocoumarin-4-acetic acid
  • HY-D1556
    DOPE-CF

    		Fluorescent Dye Others
    DOPE-CF is a pH-sensitive fluorescent membrane labelled probe with a fluorescein moiety that is a weak acid and a conjugated base that is highly fluorescent and can be attached to phospholipid ethanolamine lipids .
    DOPE-CF
  • HY-W020798
    1-Palmitoyl-2-[3-(diphenylhexatriene)propanoyl]-sn-phosphatidylcholine

    		Fluorescent Dye Others
    1-Palmitoyl-2-[3-(diphenylhexatriene)propanoyl]-sn-phosphatidylcholine is a fluorescent probe with a polar phosphatidylethanolamine head group for the determination of surface lipid oxidation in lipoproteins and plasma .
    1-Palmitoyl-2-[3-(diphenylhexatriene)propanoyl]-sn-phosphatidylcholine
  • HY-D2115
    NBDT

    		Fluorescent Dye Others
    NBDT is sensitive and selective light-up fluorescent probe for monitoring gallium and chromium ionsin vitro and in vivo and can be detected at 574 nM .
    NBDT
  • HY-W127843
    Mag-Indo-1 tetrapotassium salt

    		Fluorescent Dye Others
    Mag-Indo-1 tetrapotassium salt is a cell impermeable fluorescent probe for Mg 2+ detection .
    Mag-Indo-1 tetrapotassium salt
  • HY-D2287
    CalFluor 555 azide

    		Fluorescent Dye Others
    CalFluor 555 azide is a fluorogenic azide probe. CalFluor 555 azide is not fluorescent until it is reacted with alkynes (Ex=555 nm) .
    CalFluor 555 azide
  • HY-D2287A
    CalFluor 555 azide chloride

    		Fluorescent Dye Others
    CalFluor 555 azide (chloride) is a fluorogenic azide probe. CalFluor 555 azide (chloride) is not fluorescent until it is reacted with alkynes (Ex=555 nm) .
    CalFluor 555 azide chloride
  • HY-P6285
    Z-TPE-2DEVD

    		Fluorescent Dye Caspase Cancer
    Z-TPE-2DEVD is a specific probe for caspase-3 .
    Z-TPE-2DEVD

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: