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probes

" in MedChemExpress (MCE) Product Catalog:

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2097

Inhibitors & Agonists

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1541

Fluorescent Dye

125

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Peptides

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Products

Isotope-Labeled Compounds

197

Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-D1458

Peroxyfluor 1	Fluorescent Dye	Cardiovascular Disease Neurological Disease Cancer
Peroxyfluor 1 is a cell-permeable probe for H₂O₂. Peroxyfluor 1 represents a first-generation, green-fluorescent probe .

HY-W040681

7-Dimethylaminocoumarin-4-acetic acid	Fluorescent Dye	Others
7-Dimethylaminocoumarin-4-acetic acid is a fluorescent probe .

HY-138760

SEluc-2	Fluorescent Dye	Others
SEluc-2 is a small-molecule probe based on the firefly luciferin. SEluc-2, a bioluminescent probe for the sensitive and selective detection of thiols in living cells .

HY-D1188

*PARP7-probe-1*	PARP	Cancer
PARP7-probe-1 is a chemiluminescent labeled PARP7 probe. PARP7-probe-1 is a biotinylated probe binding to the PARP7 active site. PARP7-probe-1 can be used for the research of PARP7 function .

HY-D1478

*Fluorescent polyamine probe-1*	Fluorescent Dye	Others
Fluorescent polyamine probe-1 (compound 15) is a linear polyamine probe with high uptake efficiency. Fluorescent polyamine probe-1 can be used for the research of transport system into cancer cells .

HY-D1556

DOPE-CF	Fluorescent Dye	Others
DOPE-CF is a pH-sensitive fluorescent membrane labelled probe with a fluorescein moiety that is a weak acid and a conjugated base that is highly fluorescent and can be attached to phospholipid ethanolamine lipids .

HY-W020798

1-Palmitoyl-2-[3-(diphenylhexatriene)propanoyl]-sn-phosphatidylcholine	Fluorescent Dye	Others
1-Palmitoyl-2-[3-(diphenylhexatriene)propanoyl]-sn-phosphatidylcholine is a fluorescent probe with a polar phosphatidylethanolamine head group for the determination of surface lipid oxidation in lipoproteins and plasma .

HY-D2115

NBDT	Fluorescent Dye	Others
NBDT is sensitive and selective light-up fluorescent probe for monitoring gallium and chromium ionsin vitro and in vivo and can be detected at 574 nM .

HY-W127843

Mag-Indo-1 tetrapotassium salt	Fluorescent Dye	Others
Mag-Indo-1 tetrapotassium salt is a cell impermeable fluorescent probe for Mg ²⁺ detection .

HY-D2280

*Estrogen receptor β/HDAC probe* 1**	HDAC Estrogen Receptor/ERR	Others
Estrogen receptor β/HDAC probe 1 (compound P1) is a near-infrared fluorescent probe that dual-targets the estrogen receptor (Estrogen Receptor/ERR) β/histone deacetylase HDAC .

HY-D2342

*SARS-CoV-2 3CLpro probe-1*	Fluorescent Dye	Infection
SARS-CoV-2 3CLpro probe-1 (Compound probe 3) is a selective and activity-based probe for the SARS-CoV-2 3CL protease. SARS-CoV-2 3CLpro probe-1 can detect endogenously expressed 3CLpro in SARS-CoV-2-infected cells .

HY-D2287

CalFluor 555 azide	Fluorescent Dye	Others
CalFluor 555 azide is a fluorogenic azide probe. CalFluor 555 azide is not fluorescent until it is reacted with alkynes (Ex=555 nm) .

HY-D2287A

CalFluor 555 azide chloride	Fluorescent Dye	Others
CalFluor 555 azide (chloride) is a fluorogenic azide probe. CalFluor 555 azide (chloride) is not fluorescent until it is reacted with alkynes (Ex=555 nm) .

HY-P6285

Z-TPE-2DEVD	Fluorescent Dye Caspase	Cancer
Z-TPE-2DEVD is a specific probe for caspase-3 .

HY-D2377

F8	Fluorescent Dye	Others
F8 is a small molecule GPR84 fluorescent probe that can visualize and detect GPR84 protein levels at the cellular and tissue levels .

HY-130013

HKYellow-AM (6/12-mixture)	Fluorescent Dye	Others
HKYellow-AM (6/12-mixture) is a yellow fluorescent probe that can detect ONOO- in living cells and tissues with high selectivity and sensitivity without cytotoxicity .

HY-W337618

7-Aminocoumarin	Fluorescent Dye	Cancer
7-Aminocoumarin is highly fluorescent, acts as an optical brightener and fluorescent probe .

HY-D2188

IMP-2373	Fluorescent Dye Deubiquitinase	Cancer
IMP-2373 is the activity-based probe (ABP). IMP-2373 is a covalent pan- deubiquitinase(DUB) ABP to monitor DUB activity in physiologically relevant live cells .

HY-162160

NR12S	Fluorescent Dye	Others
NR12S is a fluorescence probe. NR12S can be used for the research of studying cholesterol and lipid order in biomembranes .

HY-129109

NBD-Pen	Fluorescent Dye	Others
NBD-Pen is a fluorescence probe. NBD-Pen can be used for the research of detection of lipid-derived radicals .

HY-D2302

mgc(3Me)DEAC	Fluorescent Dye	Others
mgc(3Me)DEAC (compound mgc3MeDEAC) is a small-molecule fluorescent probe (Ex/Em=345/445 nm ) enabling visualization of the Golgi apparatus in living cell .

HY-D2327

*DPP-8/9 probe-1*	Dipeptidyl Peptidase	Others
DPP-8/9 probe-1 (compound 20) is a fluorescent probe targeting Dipeptidyl Peptidase DPP8/9, which can be selectively labeled and visualized in vitro by fluorescence microscopy Active DPP8/9. DPP-8/9 probe-1 contains a nitrobenzoxadiazole (NBD) tag and has high affinity and selectivity for DPP8/9 over related S9 family members (IC₅₀ of 210 nM and 15 nM, respectively) .

HY-136404

*Melanin probe-1*	Others	Cancer
Melanin probe-1 is an ¹⁸F-picolinamides based PET probe. Melanin probe-1 can be used for PET imaging of malignant melanoma. Melanin probe-1 exhibits high tumor targeting efficiency, excellent tumor imaging contrasts, desirable biodistribution patterns, and good in vivo stability .

HY-D1022

Biotin-16-dUTP Biotin-16-deoxyuridine-5'-triphosphate	Fluorescent Dye	Others
Biotin-16-dUTP (Biotin-16-deoxyuridine-5'-triphosphate) can be used to replace its natural counterpart dTTP by enzymatically incorporating it into DNA/cDNA. Biotin-16- dUTP can be used to produce biotinylated DNA probes in a variety of assay applications .

HY-D1022A

Biotin-16-dUTP trisodium Biotin-16-deoxyuridine-5'-triphosphate trisodium	DNA Stain	Others
Biotin-16- dUTP (Biotin-16-deoxyuridine-5'-triphosphate) trisodium can be used to replace its natural counterpart dTTP by enzymatically incorporating it into DNA/cDNA. Biotin-16- dUTP trisodium can be used to produce biotinylated DNA probes in a variety of assay applications .

HY-W103047

1-Pyrenebutyric acid	Fluorescent Dye	Others
1-Pyrenebutyric acid is a fluorescence probe that can be used in fluorescence determination of DNA. 1-Pyrenebutyric acid can be used as a linker for biomolecules to form a self-assembled monolayer on grapheme .

HY-136219

*Protein kinase affinity probe* 1**	Others	Others
Protein kinase affinity probe 1 is a novel protein kinase affinity *probe* for the functional identification of protein kinases (PKs). Protein kinase affinity probe 1 is a modified Purvalanol B (HY-18299) probe with 50% beads loading (Compound S3) .

HY-136192

TP-472N	Epigenetic Reader Domain	Cancer
TP-472N is a negative control probe for TP-472. TP-472 is a potent and selective BRD7/9 probe .

HY-145837

*Y1R probe-1*	Neuropeptide Y Receptor	Cancer
Y1R probe-1 (Compound 39) is a high-affinity fluorescence probe for the Neuropeptide Y Y1 Receptor. Y1R probe-1 has the potential for the research of cancer disease .

HY-D1148

HKGreen-4I 1 Publications Verification	Fluorescent Dye	Others
HKGreen-4I is a highly sensitive green fluorescent probe for the specific detection of ONOO ^- in living cells with a maximum excitation wavelength and emission wavelength of 520 nm and 543 nm, respectively .

HY-D2336

PROTAC Aster-A degrader-1	PROTACs	Cancer
PROTAC Aster-A degrader-1 (compound NGF3) is a degrader of the sterol transport protein Aster-A. PROTAC Aster-A degrader-1 can be used as a fluorescence probe. (Red: Aster-A inhibitor, black: linker, Blue: E3 ligase ligand) .

HY-147177

Bodipy 8-chloromethane	Fluorescent Dye	Others
BODIPY-8-chloromethane is a fluorophore. BODIPY-8-chloromethane can be used as as a fluorescent probe .

HY-D2318

Flipper-TR 5	Fluorescent Dye	Others
Flipper-TR 5 is a Flipper probe that contains a terminal carboxylate for retention on the plasma membrane. Flipper-TR 5 can selectively label the plasma membrane and exhibits excellent mechanosensitivity, negligible cytotoxicity, and manageable phototoxicity .

HY-145057

PP-biotin	Others	Cancer
PP-biotin is an irreversible, biotin-labeled probe .

HY-D1151

HKOH-1	Reactive Oxygen Species Fluorescent Dye	Others
HKOH-1 is a highly sensitive green fluorescent probe for the specific detection of ·OH in living cells with a maximum excitation wavelength and emission wavelength of 500 nm and 520 nm, respectively .

HY-D0127

Merocyanin 540	Fluorescent Dye	Others
Merocyanin 540 is a fluorescent membrane probe that selectively stains the membranes of a wide variety of electrically excitable cells, but not those of nonexcitable cells (Ex/Em: 540/580 nm) .

HY-149680

CatD-P1	Others	Others
CatD-P1is a pH insensitive CatD (Cathepsin D) probe .

HY-D2315

Probe-Cys	Fluorescent Dye	Cancer
Probe-Cys is a water-soluble and selective near-infrared fluorescent probe for Cys (λex= 680 nm, λem=710 nm) that is not interfered by Hcy, GSH, and HS-. Probe-Cys can react with the stimulant 1,4-dimercaptothreitol (DTT) and the inhibitor N-ethylmaleimide (NEM) in HepG2 cells and zebrafish for the detection of endogenous Cys. Probe-Cys can also be used for imaging Cys in Arabidopsis thaliana. Probe-Cys provides a method for cancer diagnosis and exploration of plant sulfur metabolism .

HY-B1025

Digoxigenin Lanadigenin	Fluorescent Dye	Inflammation/Immunology
Digoxigenin (DIG) is a steroid. DIG is used for situ hybridization as a labeling molecule probe due to long shelf life and fast detection and high sensitivity of DIG-labeled riboprobes .

HY-D0941

5-Carboxytetramethylrhodamine	Fluorescent Dye	Others
5-Carboxytetramethylrhodamine can be used as a fluorescent probe of nucleic acids and proteins. 5-Carboxytetramethylrhodamine displays excitation maxima of 558 nm and an emission maximum of 586 nm .

HY-D1107

NCT-TFP	PARP	Others
NCT-TFP is PARP probe used to identifying Poly(ADP-ribose) polymerases (PARP) inhibitors (extracted from patent US20190331688A1) .

HY-P3791

N-Succinyl-Ile-Ile-Trp-AMC	Fluorescent Dye	Others
N-Succinyl-Ile-Ile-Trp-AMC is a peptide-based fluorescent substrate or probe for carboxypeptidase Y (CPY) .

HY-147652

*G-quadruplex DNA fluorescence probe* 1**	DNA Stain	Others
G-quadruplex DNA fluorescence probe 1 (Compound E1) is a selective G-quadruplex DNA targeting fluorescent probe. G-quadruplex DNA fluorescence probe 1 can pass through membrane and enter living cells with low cytotoxicity .

HY-149761

GSK023	Epigenetic Reader Domain	Others
GSK023 (compound 31) is a selective chemical probe targeting the BET BD1 domain .

HY-W040143

2',7'-Dichlorofluorescein	Reactive Oxygen Species	Cancer
2',7'-Dichlorofluorescein acts as a fluorescent probe (Ex=496 nm and Em=525 nm) for reactive oxygen species (ROS) measurement .

HY-D2312

Mito-Rh-S	Fluorescent Dye Ferroptosis	Cancer
Mito-Rh-S is a ratiometric near-infrared (NIR) fluorescent probe that detects the fluctuation of mitochondrial HClO levels during ferroptosis in hepatocellular carcinoma (HCC) .

HY-D1386

JF526-Taxol TFA	Fluorescent Dye	Others
JF526-Taxol (TFA) is a versatile scaffold for fluorogenic probes including ligands for self-labeling tags, stains for endogenous structures, and spontaneously blinking labels for super-resolution immunofluorescence .

HY-130015

HKSOX-1 (5/6-mixture) 2 Publications Verification	Reactive Oxygen Species	Others
HKSOX-1 is a fluorescent probe which is used for imaging and detection of endogenous superoxide in live cells and in vivo. HKSOX-1 exhibits excellent selectivity and sensitivity towards superoxide anion radical .

HY-D2260

hMSCs-Neu perchlorate	Fluorescent Dye	Neurological Disease
hMSCs-Neu perchlorate (Compound 4) is a fluorescent probe that converts hMSCs into neurons in the presence of fibroblast growth factor (FGF). hMSCs-Neu perchlorate may have important applications in neuropathology and neurodegeneration research .

HY-D2322

SupraFlipper 31	Fluorescent Dye	Others
SupraFlipper 31 is a fluorescent probe. SupraFlipper 31 can be released in the membrane of interest (MOI) via chemical stimulation.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B1025

Digoxigenin Lanadigenin	Structural Classification Microorganisms Classification of Application Fields Source classification Scrophulariaceae Plants Rehmannia glutinosa (Gaert.) Libosch. ex Fisch. et Mey Inflammation/Immunology Disease Research Fields Steroids	Fluorescent Dye
Digoxigenin (DIG) is a steroid. DIG is used for situ hybridization as a labeling molecule probe due to long shelf life and fast detection and high sensitivity of DIG-labeled riboprobes .

HY-W091541

4-Hydroxy-1H-indole-3-carbaldehyde 4-Hydroxyindole-3-carboxaldehyde	Alkaloids Monophenols Classification of Application Fields Capparis spinosa L. Source classification Other Diseases Phenols Plants Capparidaceae Disease Research Fields Indole Alkaloids	Others
4-Hydroxy-1H-indole-3-carbaldehyde is a plant metabolite found in Capparis spinosa L.. 4-Hydroxy-1H-indole-3-carbaldehyde can be used in the synthesis of fluorescent probe .

HY-W007324

Maleimide	Alkaloids Microorganisms Pyrrole Alkaloids Other Alkaloids Source classification Endogenous metabolite Disease Research Fields Cancer	ADC Linker
Maleimide can be used for production of antibody-drug conjugate (ADC) which is used in cancer research. Maleimide also be leveraged for the preparation of fluorogenic probe, which is mainly used for the specific detection of thiol analytes .

HY-N7131

Coumarin 6 5+ Cited Publications	Alkaloids Structural Classification Classification of Application Fields Source classification Other Diseases Umbelliferae Plants Disease Research Fields Indole Alkaloids Ambrosia hispida	Fluorescent Dye
Coumarin 6, a fluorescent dye, is used as a fluorescent probe in a microparticle drug delivery system to conduct in vivo tracking, cell uptake, and transport mechanism studies of drug delivery systems (λ_exc=450 nm, λ_em=505 nm) .

HY-Y1309

1-Naphthol Furro ER; NSC 9586; Nako TRB	Monophenols Classification of Application Fields Source classification Other Diseases Phenols Endogenous metabolite Disease Research Fields	Endogenous Metabolite
1-naphthol is an excited state proton transfer (ESPT) fluorescent molecular probe.

HY-18743

Coelenterazine 3 Publications Verification	Alkaloids Structural Classification Monophenols Animals Classification of Application Fields Other Alkaloids Source classification Phenols Polyphenols Disease Research Fields Cancer	Reactive Oxygen Species
Coelenterazine is a luminescent enzyme substrate for apoaequorin and Renilla luciferase. Renilla luciferase and substrate coelenterazine has been used as the bioluminescence donor in bioluminescence resonance energy transfer (BRET) to detect protein-protein interactions. Coelenterazine is a superoxide anion-sensitive chemiluminescent probe and it can also be used in chemiluminescent detection of peroxynitrite .

HY-113352

7-Methylguanine	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
7-Methylguanine is a metabolite of DNA methylation. It can be generated by methylating agents, and used as a probe of protein–DNA interactions and a key component of DNA sequencing method.

HY-B1025R

Digoxigenin (Standard)	Structural Classification Microorganisms Source classification Scrophulariaceae Plants Rehmannia glutinosa (Gaert.) Libosch. ex Fisch. et Mey Steroids	Fluorescent Dye
Digoxigenin (Standard) is the analytical standard of Digoxigenin. This product is intended for research and analytical applications. Digoxigenin (DIG) is a steroid. DIG is used for situ hybridization as a labeling molecule probe due to long shelf life and fast detection and high sensitivity of DIG-labeled riboprobes .

HY-160240

HPI	Classification of Application Fields Disease Research Fields Cancer	Others
HPI is a HS ^- fluorescent probe (Ex/Em=280/410 nm). HPI can be used to detect the HS ^- form of hydrogen sulfide (H₂S) gas in environmental water samples .

HY-N12931

Maackia amurensis Lectin (MAA/MAL II)	Structural Classification Natural Products Leguminosae Source classification Maackia amurensis Rupr. et Maxim. Plants	Fluorescent Dye
Maackia amurensis Lectin (MAA/MAL II) is a plant lectin. Maackia amurensis Lectin (MAA/MAL II) has specific sugar recognition properties and is able to bind to molecules containing specific sugar structures, especially the α-2, 3-linked Lactaminic acid (HY-I0400), which can be used as a probe to specifically bind biomolecular molecules. Maackia amurensis Lectin (MAA/MAL II) can be used for the discovery of disease-related biomarkers and the study of cancer pathologic mechanisms .

HY-N6989

Isoglycycoumarin	Classification of Application Fields Leguminosae Source classification Coumarins Phenols Polyphenols Metabolic Disease Phenylpropanoids Plants Disease Research Fields Glycyrrhiza uralensis Fisch.	Cytochrome P450
Isoglycycoumarin is a flavonoid isolated from the roots of Glycyrrhiza uralensis. Isoglycycoumarin is a highly selective probe for human cytochrome P450 2A6 (CYP2A6) .

HY-153783

OBI	Classification of Application Fields Disease Research Fields Cancer	Fluorescent Dye
OBI is a Red Broccoli probe with red fluorescence. OBI enables Red Broccoli to be easily detected in living mammalian cells. OBI can be used to monitor intracellular metabolites .

HY-Y1309R

1-Naphthol (Standard)	Structural Classification Monophenols Source classification Phenols Endogenous metabolite	Endogenous Metabolite
1-Naphthol (Standard) is the analytical standard of 1-Naphthol. This product is intended for research and analytical applications. 1-naphthol is an excited state proton transfer (ESPT) fluorescent molecular probe.

HY-W038786

2,4,6-Trimethylphenol	Structural Classification Monophenols Classification of Application Fields Source classification Other Diseases Phenols Endogenous metabolite Disease Research Fields	Others
2,4,6-Trimethylphenol is a probe compound shown to react mainly with organic matter ( ³DOM ^*). 2,4,6-Trimethylphenol is rapidly oxidized by singlet oxygen in aqueous solution .

HY-P3443

Peanut agglutinin PNA	Natural Products Arachis hypogaea L. Classification of Application Fields Leguminosae Source classification Other Diseases Plants Disease Research Fields	Fluorescent Dye
Peanut agglutinin (PNA) is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Peanut agglutinin (PNA) is a biological material or organic compound that can be used in life science research .

HY-110016

Docosatetraenylethanolamide DEA	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Endogenous Metabolite Cannabinoid Receptor
Docosatetraenylethanolamide (DEA) is a cannabinoid receptor 1 (CB1) agonist. Docosatetraenylethanolamide inhibits the specific binding of cannabinoid probe to rat synaptosomal membranes with a K_i value of 34.4 nM. Docosatetraenylethanolamide can be used in the research of nervous system .

HY-P99834

Crefmirlimab 89Zr-Df-IAB22M2C	Classification of Application Fields Disease Research Fields Cancer	Others
Crefmirlimab (89Zr-Df-IAB22M2C) is an anti-human CD8 probe targeting CD8 antigen, which can be used in the diagnosis of various cancers .

HY-N7550

Latrunculin M	Structural Classification Natural Products Marine natural products Source classification Sponge	Others
Latrunculin M is a highly selective actin-macrolide conjugate that can be isolated from marine products. Latrunculin M can be converted from Latrunculin B, which can effectively induce actin depolymerization and is a good probe for detecting the actin skeleton.

HY-17026E

Gemcitabine triphosphate trisodium dFdCTP trisodium	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite
Gemcitabine triphosphate (trisodium) is one of the two nucleoside metabolites of Gemcitabine (HY-17026) in cells. The other is active diphosphate (dFdDTP). Gemcitabine triphosphate can be used as a standard in radio-labeled probe imaging studies, to identify tumors sensitive to Gemcitabine, and to evaluate Gemcitabine uptake and retention by cells .

HY-17026A

Gemcitabine triphosphate dFdCTP	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Cancer	Drug Metabolite Endogenous Metabolite
Gemcitabine triphosphate (dFdCTP) is one of the two nucleoside metabolites of Gemcitabine (HY-17026) in cells. The other is active diphosphate (dFdDTP). Gemcitabine triphosphate can be used as a standard in radio-labeled probe imaging studies, to identify tumors sensitive to Gemcitabine, and to evaluate Gemcitabine uptake and retention by cells .

HY-118667

Dehydroergosterol	Microorganisms Source classification	Liposome
Dehydroergosterolis a naturally occurring fluorescent sterol analog (Ex/Em=325/375 nm), which mimics the properties of cholesterol in cell membranes. DehydroergosterolEasily conjugated by cholesterol-binding proteins for real-time imaging in live cells. DehydroergosterolThe sterol environment and intracellular sterol transport in vivo can be probed/elucidated in real time .

HY-P1004

Luciferase	Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields Cancer	Reactive Oxygen Species
Luciferase from Vibrio fischeri has also been used in a study to investigate the sensitivity of dark mutants of various strains of luminescent bacteria to reactive oxygen species.

HY-N6716

Filipin complex Maximum Cited Publications 14 Publications Verification	Structural Classification Microorganisms Antifungal Classification of Application Fields Antibiotics Source classification Other Diseases Antiviral Disease Research Disease Research Fields Other Antibiotics	Fungal Antibiotic
Filipin complex is a potent polyene macrolide antifungal antibiotic. Filipin complex inserts into membranes and sequester cholesterol into complexes and inhibits PRRSV entry. The Filipin complex consists of about 75.8% Filipin III (HY-N6718), 10.8% Filipin IV, 9.1% Filipin II, and 1.2% Filipin I .

HY-D0226

Quinizarin 1,4-Dihydroxyanthraquinone	Infection Quinones Structural Classification Classification of Application Fields Anthraquinones Source classification Phenols Polyphenols Solanaceae Plants Disease Research Fields Rhizophora mucronata Lam	DNA/RNA Synthesis Fungal
Quinizarin (1,4-Dihydroxyanthraquinone), a part of the anticancer agents such as Doxorubicin, Daunorubicin, and Adriamycin, interacts with DNA by intercalating mode (K_d=86.1 μM). Quinizarin is used as a fungicide and pesticide chemical and has shown the ability to inhibit tumor cell growth .

HY-D0016

5-Cyano-2,3-di-(p-tolyl)tetrazolium chloride CTC	Classification of Application Fields Disease Research Fields Cancer	Fluorescent Dye
5-Cyano-2,3-di-(p-tolyl)tetrazolium chloride (CTC) is a redox-sensitive red fluorescent dye. 5-Cyano-2,3-di-(p-tolyl)tetrazolium chloride can be used for detecting metabolic activity in microorganisms. The emission maximum of 5-Cyano-2,3-di-(p-tolyl)tetrazolium chloride is 602 nm .

HY-D0069

CPM	Classification of Application Fields Disease Research Fields Cancer	Fluorescent Dye
CPM is a maleimide derivative, acting as a blue fluorescent thiol-reactive dye. The excitation/emission maxima is 384/470 nm .

HY-N2306

Aclacinomycin A 3 Publications Verification Aclarubicin	Quinones Structural Classification Microorganisms Anthraquinones	Topoisomerase DNA/RNA Synthesis Proteasome Antibiotic
Aclacinomycin A (Aclarubicin) is an orally active and potent anthracycline antitumor antibiotic. Aclacinomycin A is an inhibitor of topoisomerase I and II. Aclacinomycin A inhibits synthesis of nucleic acid, especially RNA. Aclacinomycin A might inhibit the 26S protease complex as well as the ubiquitin-ATP-dependent proteolysis .

HY-B0315A

Biotin-Vitamin B12	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Biotin-Vitamin B12 is the biotinylated Vitamin B12. Vitamin B12 is a vitamin that plays a key role in the normal functioning of the brain and nervous system, and for the formation of blood .

HY-N2306R

Aclacinomycin A (Standard)	Quinones Structural Classification Microorganisms Anthraquinones	Topoisomerase DNA/RNA Synthesis Proteasome Antibiotic
Aclacinomycin A (Standard) is the analytical standard of Aclacinomycin A. This product is intended for research and analytical applications. Aclacinomycin A (Aclarubicin) is an orally active and potent anthracycline antitumor antibiotic. Aclacinomycin A is an inhibitor of topoisomerase I and II. Aclacinomycin A inhibits synthesis of nucleic acid, especially RNA. Aclacinomycin A might inhibit the 26S protease complex as well as the ubiquitin-ATP-dependent proteolysis .

Cat. No.	Product Name	Chemical Structure

HY-B0171S

Antipyrine-d3
Antipyrine-d₃ is the deuterium labeled Antipyrine. Antipyrine (Phenazone) is an antipyretic and analgesic. Antipyrine can be used as a probe agent for oxidative agent metabolism. Antipyrine has been widely used in assessment of hepatic oxidative capacity[1][2].

HY-A0081S

Fluphenazine-d8 dihydrochloride
Fluphenazine-d₈ (dihydrochloride) is the deuterium labeled Fluphenazine dihydrochloride. Fluphenazine dihydrochloride is a phenothiazine-class D1DR and D2DR inhibitor; used to deliver Fluphenazine to biological systems in studies probing the effects and metabolic fates of this commonly used dopamine antagonist.

HY-B0476S

Phenacetin-d5
Phenacetin-d₅ is the deuterium labeled Phenacetin. Phenacetin (Acetophenetidin) is a non-opioid analgesic/antipyretic agent. Phenacetin is a selective COX-3 inhibitor. Phenacetin is used as probe of cytochrome P450 enzymes CYP1A2 in human liver microsomes and in rats[1][2][3].

HY-B1422S

9-Aminoacridine-13C6

9-Aminoacridine-13C6 is the ¹³C-labeled 9-Aminoacridine(HY-B1422). 9-Aminoacridine, a fluorescent probe, acts as an indicator of pH for quantitative determination of transmembrane pH gradients (inside acidic). 9-Aminoacridine is an antimicrobial. 9-Aminoacridine exerts its antimicrobial activity by interacting with specific bacterial DNA and disrupting the proton motive force in K. pneumoniae. 9-Aminoacridine is a HIV-1 inhibitor and inhibits HIV LTR transcription highly dependent on the presence and location of the amino moiety. 9-Aminoacridine inhibits virus replication in HIV-1 infected cell lines. 9-Aminoacridine is used as a Rifampin (RIF; HY-B0272) adjuvant for the multidrug-resistant K. pneumoniae infections .

HY-Y1309S

1-Naphthol-d8
1-Naphthol-d₈ is the deuterium labeled 1-Naphthol[1]. 1-naphthol is an excited state proton transfer (ESPT) fluorescent molecular probe[2].

HY-113352S

7-Methylguanine-d3
7-Methylguanine-d₃ is the deuterium labeled 7-Methylguanine[1]. 7-Methylguanine is a metabolite of DNA methylation. It can be generated by methylating agents, and used as a probe of protein–DNA interactions and a key component of DNA sequencing method[2].

HY-B0476S1

Phenacetin-13C
Phenacetin- ¹³C is the ¹³C labeled Phenacetin[1]. Phenacetin (Acetophenetidin) is a non-opioid analgesic/antipyretic agent. Phenacetin is a selective COX-3 inhibitor. Phenacetin is used as probe of cytochrome P450 enzymes CYP1A2 in human liver microsomes and in rats[2][3][4].

HY-157585S

21-Dehydro Budesonide-d8-1
21-Dehydro Budesonide-d8-1 is deuterated labeled dehydrogenated Budesonide (HY-13580). Budesonide is an orally available glucocorticoid receptor agonist with anti-cancer activity. 21-Dehydro Budesonide-d8-1 acts as a probe for glucocorticoid receptors and is used in isotope tracing studies .

HY-108286S

(Rac)-Talinolol-d5
(Rac)-Talinolol-d₅ is the racemate of Talinolol. Talinolol (Cordanum) is a long-acting, cardioselective β1-adrenergic receptor blocker. Talinolol exhibits cardioprotective and antihypertensive activities. Talinolol is also a well-known and frequently used probe substrate for P-glycoprotein (P-gp) activity[1][2][3].

HY-W038786S

2,4,6-Trimethylphenol-d11
2,4,6-Trimethylphenol-d₁₁ is the deuterium labeled 2,4,6-Trimethylphenol[1]. 2,4,6-Trimethylphenol is a probe compound shown to react mainly with organic matter (3DOM*). 2,4,6-Trimethylphenol is rapidly oxidized by singlet oxygen in aqueous solution[2][3].

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