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5,5’-dlthlobls

" in MedChemExpress (MCE) Product Catalog:

2323

Inhibitors & Agonists

15

Screening Libraries

91

Fluorescent Dye

122

Biochemical Assay Reagents

103

Peptides

2

MCE Kits

19

Inhibitory Antibodies

365

Natural
Products

46

Recombinant Proteins

291

Isotope-Labeled Compounds

23

Antibodies

40

Click Chemistry

165

Oligonucleotides

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-D1539
    Cyanine 5.5 azide

    CY 5.5 azide; Lumiprobe CY 5.5 azide

    		 Fluorescent Dye Others
    Cyanine 5.5 azide (CY 5.5 azide) is a potent fluorescent dye. Cyanine 5.5 azide can label DNA. Cyanine 5.5 azide can be used for NIR live organism imaging. (λex=684 nm, λem=710 nm) . Cyanine 5.5 azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    Cyanine 5.5 azide
  • HY-D1540
    Cyanine5.5 amine

    Cy 5.5 amine; Lumiprobe Cy 5.5 amine

    		 Fluorescent Dye Others
    Cyanine5.5 amine (Cy 5.5 amine), a Cy5.5 Analogue, is a near-infrared (NIR) fluorescent dye (Ex=648 nm, Em=710 nm). Cyanine5.5 amine can be used in the preparation of Cy5.5-labeled nanoparticles, which can be tracked and imaged with low fluorescence background using confocal microscopy .
    Cyanine5.5 amine
  • HY-D1040
    CY5.5-COOH

    Cyanine 5.5 carboxylic acid

    		 Fluorescent Dye Others
    CY5.5-COOH (Cyanine 5.5 carboxylic acid) is a fluorescent dye, is commonly used in bioimaging. CY5.5-COOH shows narrow absorption spectrum, and high sensitivity and stability .
    CY5.5-COOH
  • HY-Y1968A
    Sterile 10 mM Histidine, pH 5.5 buffer

    		Biochemical Assay Reagents Others
    Sterile 10 mM Histidine, pH 5.5 buffer is a multi-purpose buffer solution with important applications in many fields such as protein purification, vaccine preparation, drug development, cell culture and electrophoresis. Histidine is an amino acid with good buffering capacity. Sterile 10 mM Histidine, pH 5.5 buffer The sterility and specific pH conditions make it ideal for experiments that require precise control of environmental conditions. The histidine in Sterile 10 mM Histidine, pH 5.5 buffer derivatizes photosensitizers that accumulate and increase greatly upon exposure to light. Histidine-derived photosensitizers are also the primary mediators of tryptophan photooxidation .
    Sterile 10 mM Histidine, pH 5.5 buffer
  • HY-D1537
    Dibenzocyclooctyne-Cy5.5

    DBCO-Cy5.5; Cyanine5.5 DBCO

    		 Fluorescent Dye Others
    Dibenzocyclooctyne-Cy5.5 (DBCO-Cy5.5) is a fluorescent dye. Dibenzocyclooctyne-Cy5.5 can be used to syntheses calcium-binding near-infrared fluorescent nanoprobe for bone tissue imaging .
    Dibenzocyclooctyne-Cy5.5
  • HY-D1557
    Cyanine5.5 tetrazine

    		Fluorescent Dye Others
    Cyanine5.5 tetrazine is a far-infrared luminescent dye. Cyanine5.5 tetrazine is a Cyanine5.5 (HY-D0925A) derivative contains a tetrazine moiety. Cyanine5.5 tetrazine can be used for in vivo imaging and low background applications. Cyanine5.5 tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
    Cyanine5.5 tetrazine
  • HY-D1040A
    CY5.5-COOH chloride

    Cyanine 5.5 carboxylic acid chloride

    		 Fluorescent Dye Others
    CY5.5-COOH (Cyanine 5.5 carboxylic acid) chloride is a fluorescent dye, is commonly used in bioimaging. CY5.5-COOH chloride shows narrow absorption spectrum, and high sensitivity and stability .
    CY5.5-COOH chloride
  • HY-B1610K
    Sodium Citrate Buffer, 0.5M, pH 5.5

    		Biochemical Assay Reagents Others
    Sodium citrate buffer, 0.5M, pH 5.5, is a commonly used buffer with main components are citric acid and sodium hydrogen phosphate. Sodium citrate buffer 0.5M pH 5.5 is used in heat induced epitope retrieval (HIER) methods to reverse the loss of antigenicity that occurs with some epitopes in formalin-fixed paraffin embedded tissues. Sodium citrate buffer 0.5M pH 5.5 is the preferred solution for most antibodies. .
    Sodium Citrate Buffer, 0.5M, pH 5.5
  • HY-D2358
    Glucosamine-CY5.5

    		Fluorescent Dye Metabolic Disease
    Glucosamine-CY5.5 is CY5.5-labeled Glucosamine (HY-B1125). Glucosamine-CY5.5 can be used to localize Glucosamine in living cells .
    Glucosamine-CY5.5
  • HY-146433
    Anticancer agent 55

    		Apoptosis Cancer
    Anticancer agent 55 is a potent anticancer agent. Anticancer agent 55 shows anticancer activity via reducing the cell viability and cell migration in a dose-dependent manner. Anticancer agent 55 induces apoptosis. Anticancer agent 55 has the potential for the research of prostate cancer and breast cancer .
    Anticancer agent 55
  • HY-101029
    MBM-55

    		NEKs Apoptosis Cancer
    MBM-55 is a potent NIMA-related kinase 2 (Nek2) inhibitor with an IC50 of 1 nM. MBM-55 shows a 20-fold or greater selectivity in most kinases with the exception of RSK1 (IC50=5.4 nM) and DYRK1a (IC50=6.5 nM). MBM-55 effectively inhibits the proliferation of cancer cells by inducing cell cycle arrest and apoptosis. MBM-55 shows antitumor activities, and no obvious toxicity to mice .
    MBM-55
  • HY-147186
    5,5'-Difluoro BAPTA

    		Others Others
    5,5'-Difluoro BAPTA is a difluoro-derivative of BAPTA (HY-100168). 5,5'-Difluoro BAPTA is the most widely used probe for studying cytosolic free Ca 2+ by 19F NMR. 5,5'-Difluoro BAPTA has high selectivity for Ca 2+. 5,5'-Difluoro BAPTA can inhibit the growth of pollen tube .
    5,5'-Difluoro BAPTA
  • HY-120450
    CL-55

    		Bacterial Infection Inflammation/Immunology
    CL-55 is an inhibitor for type three secretion system of Chlamydia trachomatis, that blocks the effector molecules delivery of bacteria into host cells. CL-55 ameliorates the C. trachomatis infection and inflammation in mice .
    CL-55
  • HY-120736
    MEB55

    		Others Cancer
    MEB55 is an antitumor agent. MEB55 shows anti-proliferative activity. MEB55 has the potential for the research of prostate cancer .
    MEB55
  • HY-D1389
    Sulfo-CY-5.5 NHS ester tripotassium

    Sulfo-Cyanine5.5 NHS ester tripotassium

    		 Fluorescent Dye Others
    Sulfo-CY-5.5 NHS ester (Sulfo-Cyanine5.5 NHS ester) tripotassium is an amine-reactive ester of sulfonated far-red Cyanine5.5 fluorophore, which can be used to label antibodies, proteins, etc., as well as for in vivo NIR imaging .
    Sulfo-CY-5.5 NHS ester tripotassium
  • HY-161059
    ZB-R-55

    		RIP kinase Infection
    ZB-R-55 is an orally active RIPK1 inhibitor. ZB-R-55 can be used for sepsis study .
    ZB-R-55
  • HY-NP062
    Bovine Serum Albumin-Cy5.5

    BSA-Cy5.5

    		 Fluorescent Dye Others
    Bovine Sermu Albumin-Cy5.5 is Cy5.5-labeled Bovine Sermu Albumin (BSA, HY-D0842) .
    Bovine Serum Albumin-Cy5.5
  • HY-151720
    Cy5.5 DBCO

    		ADC Linker Others
    Cy5.5 DBCO is a click chemistry reagent containing an cycloalkynes group. Cy5.5 DBCO is a linker of Cyanine5.5 fluorophore. DBCO group enables copper free biocompatible click chemistry with fast reaction kinetics and good stability .
    Cy5.5 DBCO
  • HY-146038
    Antitumor agent-55

    		Apoptosis ROS Kinase MDM-2/p53 Bcl-2 Family Cancer
    Antitumor agent-55 (compound 5q) is a potent antitumor agent. Antitumor agent-55 effectively inhibits PC3, with an IC50 of 0.91 μM. Antitumor agent-55 effectively inhibits the colony formation, suppresses the cell migration in PC3. Antitumor agent-55 induces G1/S phase arrest and apoptosis in PC3 .
    Antitumor agent-55
  • HY-107397
    Ch55
    2 Publications Verification

    		 RAR/RXR Cancer
    Ch55 is a potent synthetic retinoid. Ch55 binds to RAR-α and RAR-β receptors with high affinity. Ch55 displays low affinity for cellular retinoic acid binding protein (CRABP). Ch55 is a potent inducer of the differentiation of HL60 cells with an EC50 of 200 nM. Ch55 can be used for cancer research .
    Ch55
  • HY-124727
    ZT55

    		JAK Apoptosis Cancer
    ZT55 is an orally active and highly-selective JAK2 inhibitor with an IC50 value of 0.031 μM. ZT55 inhibits the proliferation of JAK2 V617F-expressing HEL cell lines and induces apoptosis and cycle arrest. ZT-55 also effectively inhibits the growth of HEL xenograft tumours in a mice model. ZT-55 can be used in studies of myeloproliferative neoplasms, polycythemia vera and primary thrombocythemia .
    ZT55
  • HY-D1882
    Cy5.5 hydrazide

    		Fluorescent Dye Others
    Cy5.5 hydrazide is a fluorescent dye containing a hydrazide functionality. Cy5.5 hydrazide can be used to label aldehydes and ketones .
    Cy5.5 hydrazide
  • HY-D2224
    Sulfo-Cy5.5 dUTP

    		Fluorescent Dye Others
    Sulfo-Cy5.5 dUTP is a dUTP far-infrared fluorescent dye containing sulfonated Cyanine5.5 group .
    Sulfo-Cy5.5 dUTP
  • HY-116888
    BFE-55

    		Adrenergic Receptor Endocrinology
    BFE-55 is a derivative of befunolol and a β-adrenergic partial agonist .
    BFE-55
  • HY-D1640
    5',5-Difluoro BAPTA tetrapotassium

    		Biochemical Assay Reagents Others
    5,5'-Difluoro BAPTA tetrapotassium is a difluoro-derivative of BAPTA (HY-100168). 5,5'-Difluoro BAPTA tetrapotassium shows large 19F NMR chemical shifts upon chelating divalent cations. 5,5'-Difluoro BAPTA tetrapotassium has high selectivity for Ca 2+. 5,5'-Difluoro BAPTA tetrapotassium can inhibit the growth of pollen tube .
    5',5-Difluoro BAPTA tetrapotassium
  • HY-D2132
    Sulfo-Cy5.5-ALN

    		Fluorescent Dye Cancer
    Sulfo-Cy5.5-ALN is a fluorescent labeled alendronate, which targets bone. Sulfo-Cy5.5-ALN binds to hydroxyapatite and differentiated osteoblasts in vitro. Sulfo-Cy5.5-ALN selectively binds to the mineralized areas of the tumor. Sulfo-Cy5.5-ALN can be used to detect bone overgrowth in prostate bone metastasis .
    Sulfo-Cy5.5-ALN
  • HY-162770
    Antiproliferative agent-55

    		Others Cancer
    Antiproliferative agent-55 (Compound 2d) is an anti-proliferative agent that can inhibit the growth of cancer cells. Antiproliferative agent-55 can be used in cancer research .
    Antiproliferative agent-55
  • HY-D1541
    Sulfo-Cyanine5.5 alkyne

    		Fluorescent Dye Others
    Sulfo-Cyanine5.5 alkyne, a near-infrared (NIR) fluorescent dye, is an alkyne modified Sulfo-Cyanine5.5 (Ex=67 8nm, Em=694 nm). Sulfo-Cyanine5.5 alkyne can react with azides for Click Chemistry labeling.
    Sulfo-Cyanine5.5 alkyne
  • HY-153620
    Antifungal agent 55

    		Fungal Infection
    Antifungal agent 55 (compound A07) is a potent antifungal agent, against Fluconazole (HY-B0101)-resistant strains. Antifungal agent 55 is more effective than Miconazole (HY-B0454). Antifungal agent 55 inhibits Candida albicans strains with MIC values of 0.25-1 μg/mL .
    Antifungal agent 55
  • HY-101029A
    MBM-55S

    		NEKs Ribosomal S6 Kinase (RSK) DYRK Apoptosis Cancer
    MBM-55S is a potent NIMA-related kinase 2 (Nek2) inhibitor with an IC50 of 1 nM. MBM-55S shows a 20-fold or greater selectivity in most kinases with the exception of RSK1 (IC50=5.4 nM) and DYRK1a (IC50=6.5 nM). MBM-55S effectively inhibits the proliferation of cancer cells by inducing cell cycle arrest and apoptosis. MBM-55S shows antitumor activities, and no obvious toxicity to mice .
    MBM-55S
  • HY-D1324
    Cyanine5.5 hydrazide dichloride

    		Fluorescent Dye Others
    Cyanine5.5 hydrazide, an analog of Cyanine5.5 fluorophore, is a near-infrared (NIR) fluorescent dye. Cyanine5.5 hydrazide is used for labeling of biomolecules through the condensation between the hydrazide groups and the carbonyl groups. (λex=684 nm, λem=710 nm) .
    Cyanine5.5 hydrazide dichloride
  • HY-141519
    PI-55

    		Parasite Infection
    PI-55 is a specific cytokinin receptor inhibitor. PI-55 is structurally related to 6-benzylaminopurine (BAP) and was shown to inhibit competitively BAP binding on Arabidopsis-specific receptors CRE1/AHK4 and AHK3. PI-55 inhibits cytokinins induced haustorium formation and increased parasite aggressiveness .
    PI-55
  • HY-D1600
    Sulfo-Cyanine5.5 maleimide potassium

    		Fluorescent Dye Others
    Sulfo-Cyanine5.5 maleimide potassium is a fluorescent dye. Sulfo-Cyanine5.5 is a nearinfrared (NIR) fluorophore with excitation maximum 675 nm and emission maximum 694 nm. Sulfo-Cyanine5.5 maleimide potassium can be used for the labeling of sensitive proteins, nanoparticles, and highly hydrophylic biopolymers .
    Sulfo-Cyanine5.5 maleimide potassium
  • HY-154858
    C55 Prenol

    C55-Polyprenol

    		 Others Metabolic Disease
    C55 Prenol is an ester product.
    C55 Prenol
  • HY-151753
    Trisulfo-Cy5.5-Alkyne

    		Fluorescent Dye Others
    Trisulfo-Cy5.5-Alkyne is a click chemistry reagent containing an azide group. Trisulfo-Cy5.5-Alkyne can participate in copper-catalyzed Click Chemistry reactions. Trisulfo-Cy5.5-Alkyne is a near infrared (NIR) fluorescent anthocyanin fluorescent dye.
    Trisulfo-Cy5.5-Alkyne
  • HY-N8581
    5,5'-Dimethoxysecoisolariciresinol

    (-)-8,8'-Bisdihydrosiringenin

    		 Others Others
    5,5'-Dimethoxysecoisolariciresinol ((-)-8,8'-Bisdihydrosiringenin) is a lignin. 5,5'-Dimethoxysecoisolariciresinol can be isolated from twigs of Cinnamomum cassia .
    5,5'-Dimethoxysecoisolariciresinol
  • HY-W107077
    INF55

    		Others Infection
    INF55 is a NoA multidrug resistance pump inhibitor with the activity of inhibiting the NoA pump. The heterocomplex formed by INF55 combined with berberine shows the potential to combat the resistance of bacterial compounds. INF55 can enhance the antibacterial activity of berberine by reducing its efflux. The structural variants of INF55 can show different NoA inhibitory activities, thereby affecting the antibacterial effect of its corresponding heterocomplexes. Different derivatives of INF55 show similar activity in terms of antibacterial dose and effectiveness .
    INF55
  • HY-159194
    DSPE-PEG2000-Cy5.5

    		Liposome Cancer
    DSPE-PEG2000-Cy5.5 is a CY5.5 labeled DSPE-PEG 2000 for drug delivery and imaging .
    DSPE-PEG2000-Cy5.5
  • HY-D2388
    Sulfo CY5.5 hydrazide

    		Fluorescent Dye Others
    Sulfo CY5.5 hydrazide is a sulfonated version of Cy5.5, which can be used to label antibodies, proteins, etc., and for in vivo NIR (far-infrared) imaging.
    Sulfo CY5.5 hydrazide
  • HY-B2176F1
    ATP-Cy5.5

    		Fluorescent Dye Others
    ATP-Cy5.5 is a Cy5.5 (HY-D0924) labled ATP (HY-B2176). ATP is a central component of energy storage and metabolism in vivo .
    ATP-Cy5.5
  • HY-112377
    MZP-55

    		Epigenetic Reader Domain PROTACs Cancer
    MZP-55 is a PROTAC connected by ligands for von Hippel-Lindau and BRD3/4, with a Kd of 8 nM for Brd4 BD2.
    MZP-55
  • HY-153068
    CZL55

    		Caspase Inflammation/Immunology
    CZL55 is a caspase-1 inhibitor with an IC50 value of 24 nM. CZL55 can be used for the research of febrile seizures (FS) .
    CZL55
  • HY-168104
    VEGFR-2-IN-55

    		VEGFR Cancer
    VEGFR-2-IN-55 (Compound 30) is a potent VEGFR-2 kinase inhibitor with an IC50 value of 1.24 nM . VEGFR-2-IN-55 has antitumor activity .
    VEGFR-2-IN-55
  • HY-152560
    HIV-1 inhibitor-55

    		HIV Infection
    HIV-1 inhibitor-55 (compound 4d) inhibits WT HIV-1 with an EC50 value of 8.6 nM. HIV-1 inhibitor-55 also shows inhibitory potency against single and double HIV-1 mutants. HIV-1 inhibitor-55 can be used for the research of virus infection .
    HIV-1 inhibitor-55
  • HY-W011651
    Carbutamide

    BZ-55

    		 Others Metabolic Disease
    Carbutamide (BZ-55) is an orally active and first-generation sulfonylurea with hypoglycemic activity .
    Carbutamide
  • HY-157206
    ICMT-IN-55

    		ICMT Cancer
    ICMT-IN-55 (compound 31) is an ICMT inhibitor with IC50=90 nM .
    ICMT-IN-55
  • HY-166279
    C55-Dihydroprenyl-mpda

    		Others Metabolic Disease
    C55-Dihydroprenyl-mpda is an ester product.
    C55-Dihydroprenyl-mpda
  • HY-D1639A
    5,5'-Dibromo-BAPTA

    		Biochemical Assay Reagents Others
    5,5'-Dibromo-BAPTA is a biochemical assay reagent.
    5,5'-Dibromo-BAPTA
  • HY-D1325
    Cyanine5.5 alkyne chloride

    		Fluorescent Dye Others
    Cyanine5.5 alkyne chloride is an alkynyl-modified near-infrared (NIR) fluorescent dye (Ex=678 nm, Em=694 nm). Cyanine5.5 alkyne chloride can react with azides for click chemistry labeling .
    Cyanine5.5 alkyne chloride
  • HY-13968
    JW 55
    2 Publications Verification

    		 PARP Cancer
    JW 55 is a potent and selective β-catenin signaling pathway inhibitor, which functions via inhibition of the PARP domain of tankyrase 1 and tankyrase 2 (TNKS1/2). JW 55 decreases auto-PARsylation of TNKS1/2 in vitro with IC50s of 1.9 μM and 830 nM respectively.
    JW 55

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