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Pathways Recommended:	Antibody-drug Conjugate/ADC Related

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Conjugates

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Linker (731) Antibody-Drug Conjugates (ADCs) (43) Drug-Linker Conjugates for ADC (286) E3 Ligase Ligand-Linker Conjugates (530) PROTAC-Linker Conjugates for PAC (5) Radionuclide-Drug Conjugates (RDCs) (32) Target Protein Ligand-Linker Conjugates (14) 17β-HSD (1) ADC Antibody (24) ADC Cytotoxin (92) Akt (5) ALCAM/CD166 (1) Aldehyde Dehydrogenase (ALDH) (1) Amino Acid Derivatives (3) Aminopeptidase (2) Amyloid-β (2) Androgen Receptor (2) ANGPTL (2) Antibiotic (16) Antifolate (3) Apolipoprotein (2) Apoptosis (157) AUTACs (4) Autophagy (181) AUTOTACs (3) Bacterial (31) Bcl-2 Family (1) BCL6 (2) Bcr-Abl (12) BCRP (1) Biochemical Assay Reagents (59) Btk (5) c-Met/HGFR (1) c-Myc (1) Casein Kinase (1) Caspase (1) CCR (1) CD19 (1) CD22 (3) CD276/B7-H3 (1) CDK (1) Checkpoint Kinase (Chk) (1) Cholinesterase (ChE) (1) CMV (1) Complement System (3) CXCR (3) Cytochrome P450 (2) DNA Alkylator/Crosslinker (16) DNA/RNA Synthesis (18) Dopamine Receptor (1) Drug Metabolite (9) E1/E2/E3 Enzyme (3) EGFR (19) Elastase (1) Endogenous Metabolite (59) Epigenetic Reader Domain (14) Estrogen Receptor/ERR (7) FAAH (1) FAP (2) Fatty Acid Synthase (FASN) (1) Ferroptosis (3) FGFR (1) Fluorescent Dye (65) Fungal (1) GABA Receptor (1) GCGR (1) GHR (2) GLP Receptor (2) Glucocorticoid Receptor (11) GLUT (3) Glutathione Peroxidase (1) Glutathione S-transferase (2) HBV (2) HCV (2) HDAC (3) HIF/HIF Prolyl-Hydroxylase (3) Histamine Receptor (2) Histone Acetyltransferase (2) Histone Demethylase (1) HIV (5) HSP (3) HSV (1) IGF-1R (1) Influenza Virus (2) Integrin (8) Interleukin Related (6) Isotope-Labeled Compounds (19) Keap1-Nrf2 (1) Kinesin (1) Lactate Dehydrogenase (1) Ligands for E3 Ligase (70) Ligands for Target Protein for PROTAC (4) Liposome (50) LXR (1) MARCKS (1) MDM-2/p53 (1) Mesothelin (1) MicroRNA (2) Microtubule/Tubulin (58) Mitochondrial Metabolism (4) Mitophagy (2) Mixed Lineage Kinase (2) Monoamine Oxidase (2) mTOR (1) Na+/K+ ATPase (1) NAMPT (5) Nectin-4 (3) Neurokinin Receptor (1) NF-κB (1) Notch (1) Nucleoside Antimetabolite/Analog (3) Opioid Receptor (1) Orthopoxvirus (2) P2Y Receptor (1) p38 MAPK (1) p62 (1) Parasite (2) PARP (1) PD-1/PD-L1 (5) PI3K (2) PKC (7) Polo-like Kinase (PLK) (1) Potassium Channel (1) PPAR (1) PROTAC Linkers (210) PROTACs (41) Proteasome (1) PSMA (4) RAR/RXR (1) Reactive Oxygen Species (4) SARS-CoV (1) Ser/Thr Protease (2) Small Interfering RNA (siRNA) (9) SNIPERs (13) Somatostatin Receptor (1) STAT (2) Stearoyl-CoA Desaturase (SCD) (1) STING (9) TAM Receptor (4) Tau Protein (1) Thyroid Hormone Receptor (1) TNF Receptor (8) Toll-like Receptor (TLR) (8) Topoisomerase (57) Transthyretin (TTR) (2) TROP2 (5) YAP (1) β-catenin (1)
By Research Areas:	Cancer (2012) Cardiovascular Disease (11) Endocrinology (4) Infection (38) Inflammation/Immunology (207) Metabolic Disease (54) Neurological Disease (30)
Click Chemistry:	ADC Synthesis (234) Labeling and Fluorescence Imaging (4) TCO (16) DBCO (67) PROTAC Synthesis (57) Azide (124) BCN (22) Tetrazine (33) Alkynes (64)
Oligonucleotides:	Fluorescent Lipids (8) Nucleotides and their Analogs (2) Pegylated Lipids (43) Liposomal Film-forming Agents (1) Aptamers (1) Emulsifiers (1) Phospholipids (3) Cationic Lipids (1) Polymers (16) Antisense Oligonucleotides (10) Cholesterol (5) siRNAs (9)

2440

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

312

Biochemical Assay Reagents

Peptides

MCE Kits

Inhibitory Antibodies

Natural
Products

Isotope-Labeled Compounds

319

Click Chemistry

Oligonucleotides

Targets Recommended: Antibody-Drug Conjugates (ADCs) Target Protein Ligand-Linker Conjugates PROTAC-Linker Conjugates for PAC Radionuclide-Drug Conjugates (RDCs) Drug-Linker Conjugates for ADC ADC Linker E3 Ligase Ligand-Linker Conjugates

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-130270

*AhR Ligand-Linker Conjugates* 1** E3 Ligase Ligand-Linker Conjugates 57	E3 Ligase Ligand-Linker Conjugates	Cancer
AhR Ligand-Linker Conjugates 1 (E3 Ligase Ligand-Linker Conjugates 57) incorporates an IAP ligand for the E3 ubiquitin ligase, and a SNIPER linker. AhR Ligand-Linker Conjugates 1 can be used to design SNIPER .

HY-125906

*VHL Ligand-Linker Conjugates* 15** E3 Ligase Ligand-Linker Conjugates 56	E3 Ligase Ligand-Linker Conjugates	Cancer
VHL Ligand-Linker Conjugates 15 incorporates an VHL ligand for the E3 ubiquitin ligase, and a PROTAC linker. VHL Ligand-Linker Conjugates 15 can be used to design PROTACs .

HY-139655

*cIAP1 Ligand-Linker Conjugates* 16**	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 16 is an E3 ligase ligand-linker conjugate that can be used in the synthesis of PROTACs.

HY-128813A

*cIAP1 Ligand-Linker Conjugates* 15 hydrochloride** E3 ligase Ligand-Linker Conjugates 34 hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 15 hydrochloride incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 15 hydrochloride can be used to design SNIPERs .

HY-128815

*cIAP1 Ligand-Linker Conjugates* 14** E3 ligase Ligand-Linker Conjugates 36	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 14 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 14 can be used to design SNIPERs .

HY-128820

*cIAP1 Ligand-Linker Conjugates* 1** E3 ligase Ligand-Linker Conjugates 41	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 1 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 1 can be used to design SNIPERs .

HY-128819

*cIAP1 Ligand-Linker Conjugates* 3** E3 ligase Ligand-Linker Conjugates 40	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 3 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 3 can be used to design SNIPERs .

HY-128812A

*cIAP1 Ligand-Linker Conjugates* 11 Hydrochloride** E3 ligase Ligand-Linker Conjugates 33 Hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 11 Hydrochloride incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 11 Hydrochloride can be used to design SNIPERs .

HY-128813

*cIAP1 Ligand-Linker Conjugates* 15** E3 ligase Ligand-Linker Conjugates 34	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 15 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 15 can be used to design SNIPERs .

HY-128812

*cIAP1 Ligand-Linker Conjugates* 11** E3 ligase Ligand-Linker Conjugates 33	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 11 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 11 can be used to design SNIPERs .

HY-128817

*cIAP1 Ligand-Linker Conjugates* 12** E3 ligase Ligand-Linker Conjugates 38	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 12 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 12 can be used to design SNIPERs .

HY-128818

*cIAP1 Ligand-Linker Conjugates* 5** E3 ligase Ligand-Linker Conjugates 39	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 5 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 5 can be used to design SNIPERs .

HY-128816

*cIAP1 Ligand-Linker Conjugates* 2** E3 ligase Ligand-Linker Conjugates 37	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 2 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 2 can be used to design SNIPERs .

HY-128822

*cIAP1 Ligand-Linker Conjugates* 13** E3 ligase Ligand-Linker Conjugates 43	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 13 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 13 can be used to design SNIPERs .

HY-128816A

*cIAP1 Ligand-Linker Conjugates* 2 Hydrochloride** E3 ligase Ligand-Linker Conjugates 37 Hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 2 Hydrochloride incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 2 Hydrochloride can be used to design SNIPERs .

HY-128826

*cIAP1 Ligand-Linker Conjugates* 10** E3 ligase Ligand-Linker Conjugates 47	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 10 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 10 can be used to design SNIPERs .

HY-128824

*cIAP1 Ligand-Linker Conjugates* 9** E3 ligase Ligand-Linker Conjugates 45	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 9 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 9 can be used to design SNIPERs .

HY-128825

*cIAP1 Ligand-Linker Conjugates* 8** E3 ligase Ligand-Linker Conjugates 46	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 8 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 8 can be used to design SNIPERs .

HY-128823

*cIAP1 Ligand-Linker Conjugates* 7** E3 ligase Ligand-Linker Conjugates 44	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 7 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 7 can be used to design SNIPERs .

HY-128821

*cIAP1 Ligand-Linker Conjugates* 4** E3 ligase Ligand-Linker Conjugates 42	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 4 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 4 can be used to design SNIPERs .

HY-128814

*cIAP1 Ligand-Linker Conjugates* 6 hydrochloride** E3 ligase Ligand-Linker Conjugates 35 hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
cIAP1 Ligand-Linker Conjugates 6 hydrochloride incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 6 hydrochloride can be used to design SNIPERs .

HY-128941

*CCK2R Ligand-Linker Conjugates* 1**	Drug-Linker Conjugates for ADC	Cancer
CCK2R Ligand-Linker Conjugates 1 is a ligand-linker conjugate, which conjugates to the cytotoxic antimicrotubule agents Desacetyl Vinblastine Hydrazide (DAVBH) and Tubulysin B Hydrazide (TubBH) via a hydrophilic peptide linker .

HY-168693

*Target Protein Ligand-Linker Conjugates* 2**	Target Protein Ligand-Linker Conjugates
Target Protein Ligand-Linker Conjugates 2 is a conjugate of the Target Protein Ligand and Linker, consisting of Desmethyl-QCA276 (HY-44103) and the corresponding Linker. Target Protein Ligand-Linker Conjugates 2 can be used to synthesize PROTAC BD-9136 (HY-149878) .

HY-133046

*VHL Ligand-Linker Conjugates* 17**	E3 Ligase Ligand-Linker Conjugates	Cancer
VHL Ligand-Linker Conjugates 17 incorporates a VHL ligand for the E3 ubiquitin ligase, and a PROTAC linker. VHL Ligand-Linker Conjugates 17 can be used in the synthesis of a series of PROTACs, such as ARD-266 (HY-133020). ARD-266 is a highly potent androgen receptor (AR) PROTAC degrader . VHL Ligand-Linker Conjugates 17 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-130499

*ERRα Ligand-Linker Conjugates* 1**	Target Protein Ligand-Linker Conjugates	Cancer
ERRα Ligand-Linker Conjugates 1 incorporates a ligand for estrogen-related receptor alpha (ERRα), and a PROTAC linker, which recruit E3 ligases MDM2. ERRα Ligand-Linker Conjugates 1 can be used in the synthesis of a series of PROTACs, such as PROTAC ERRalpha Degrader-1 (HY-128838). PROTAC ERRalpha Degrader-1 is an ERRα degrader .

HY-147225

*TSPO Ligand-Linker Conjugates* 1**	AUTACs Mitophagy	Neurological Disease Metabolic Disease Cancer
TSPO Ligand-Linker Conjugates 1 contains a ligand for translocator protein (TSPO) and a linker, which is used for the synthesis of mitochondria-targeting autophagy-targeting chimera (AUTAC). AUTAC can bind the TSPO on the outer mitochondrial membrane (OMM) of mitochondria and degrades impaired mitochondria and proteins via mitophagy, and improves mitochondrial activity. TSPO Ligand-Linker Conjugates 1 can be used in mitochondrial dysfunction related research, including neurodegenerative diseases, cancer, and diabetes .

HY-107439

Thalidomide-O-amido-C8-NH2 Cereblon Ligand-Linker Conjugates 2; E3 Ligase Ligand-Linker Conjugates 20	E3 Ligase Ligand-Linker Conjugates Autophagy Apoptosis	Cancer
Thalidomide-O-amido-C8-NH2 (Cereblon Ligand-Linker Conjugates 2), a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs .

HY-107438

Thalidomide-O-amido-C4-NH2 Cereblon Ligand-Linker Conjugates 6; E3 Ligase Ligand-Linker Conjugates 19	E3 Ligase Ligand-Linker Conjugates Autophagy Apoptosis	Cancer
Thalidomide-O-amido-C4-NH2 (Cereblon Ligand-Linker Conjugates 6), a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs .

HY-112618

Thalidomide-O-amido-C6-NH2 Cereblon Ligand-Linker Conjugates 11; E3 Ligase Ligand-Linker Conjugates 25	E3 Ligase Ligand-Linker Conjugates Autophagy Apoptosis	Cancer
Thalidomide-O-amido-C6-NH2 (Cereblon Ligand-Linker Conjugates 11), a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs .

HY-111824

VH032-thiol-C6-NH2 VHL Ligand-Linker Conjugates 14; E3 ligase Ligand-Linker Conjugates 29	E3 Ligase Ligand-Linker Conjugates	Cancer
VH032-thiol-C6-NH2 (VHL Ligand-Linker Conjugates 14) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used in PROTAC technology.

HY-128716B

Pomalidomide-PEG3-C2-NH2 hydrochloride Cereblon Ligand-Linker Conjugates 5 hydrochloride; E3 ligase Ligand-Linker Conjugates 30 hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide-PEG3-C2-NH2 (Cereblon Ligand-Linker Conjugates 5) hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology .

HY-130521

Pomalidomide-amido-PEG3-C2-NH2 Cereblon Ligand-Linker Conjugates 22; E3 ligase Ligand-Linker Conjugates 55	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide-amido-PEG3-C2-NH2 (Cereblon Ligand-Linker Conjugates 22) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology .

HY-103613

Thalidomide-O-amido-C4-NH2 TFA Cereblon Ligand-Linker Conjugates 6 TFA; E3 ligase Ligand-Linker Conjugates 19 TFA	E3 Ligase Ligand-Linker Conjugates Autophagy Apoptosis	Others
Thalidomide-O-amido-C4-NH2 TFA (Cereblon Ligand-Linker Conjugates 6 TFA) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-103614

Thalidomide-O-amido-C8-NH2 TFA 1 Publications Verification Cereblon Ligand -Linker Conjugates 2 TFA; E3 Ligase Ligand-Linker Conjugates 20 TFA	E3 Ligase Ligand-Linker Conjugates Autophagy Apoptosis	Others
Thalidomide-O-amido-C8-NH2 TFA (Cereblon Ligand -Linker Conjugates 2 TFA) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-112618A

Thalidomide-O-amido-C6-NH2 TFA Cereblon Ligand-Linker Conjugates 11 TFA; E3 Ligase Ligand-Linker Conjugates 25 TFA	E3 Ligase Ligand-Linker Conjugates Autophagy Apoptosis	Cancer
Thalidomide-O-amido-C6-NH2 TFA (Cereblon Ligand-Linker Conjugates 11 TFA), a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs .

HY-107440

Thalidomide-O-amido-PEG3-C2-NH2 Cereblon Ligand-Linker Conjugates 3 ; E3 Ligase Ligand-Linker Conjugates 14	E3 Ligase Ligand-Linker Conjugates Autophagy Apoptosis	Cancer
Thalidomide-O-amido-PEG3-C2-NH2 (Cereblon Ligand-Linker Conjugates 3) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.

HY-103612

Thalidomide-O-amido-C3-COOH Cereblon Ligand-Linker Conjugates 7; E3 ligase Ligand-Linker Conjugates 15	E3 Ligase Ligand-Linker Conjugates Autophagy Apoptosis	Cancer
Thalidomide-O-amido-C3-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-21930

Pomalidomide-PEG4-C-COOH Cereblon Ligand -Linker Conjugates 1; E3 Ligase Ligand-Linker Conjugates 1	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide-PEG4-C-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 4-unit PEG linker used in PROTAC technology.

HY-115560

Thalidomide-O-amido-C3-NH2 Cereblon Ligand-Linker Conjugates 16; E3 Ligase Ligand-Linker Conjugates 52	E3 Ligase Ligand-Linker Conjugates Autophagy Apoptosis	Cancer
Thalidomide-O-amido-C3-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-41549

Pomalidomide-PEG4-Ph-NH2 Cereblon Ligand-Linker Conjugates 9; E3 Ligase Ligand-Linker Conjugates 2	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide-PEG4-Ph-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 4-unit PEG linker used in PROTAC technology.

HY-128716A

Pomalidomide-PEG3-C2-NH2 TFA Cereblon Ligand-Linker Conjugates 5 TFA; E3 ligase Ligand-Linker Conjugates 30 TFA	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide-PEG3-C2-NH2 TFA (Cereblon Ligand-Linker Conjugates 5 (TFA)) is a synthetic E3 ligase ligand-linker conjugate comprising a Pomalidomide (HY-10984)-based cereblon ligand and a 3-unit PEG linker. Pomalidomide-PEG3-C2-NH2 TFA can be used for the synthesis of PROTACs .

HY-112599

Pomalidomide-PEG4-C2-NH2 Cereblon Ligand-Linker Conjugates 8; E3 Ligase Ligand-Linker Conjugates 22	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide-PEG4-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 4-unit PEG linker used in PROTAC technology.

HY-128716

Pomalidomide-PEG3-C2-NH2 Cereblon Ligand-Linker Conjugates 5; E3 ligase Ligand-Linker Conjugates 30	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide-PEG3-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.

HY-125884

Pomalidomide-amido-C4-amido-C6-NH-Boc Cereblon Ligand-Linker Conjugates 21; E3 Ligase Ligand-Linker Conjugates 54	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide-amido-C4-amido-C6-NH-Boc is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-115560A

Thalidomide-O-amido-C3-NH2 TFA Cereblon Ligand-Linker Conjugates 16 TFA; E3 Ligase Ligand-Linker Conjugates 52 TFA	E3 Ligase Ligand-Linker Conjugates Autophagy Apoptosis	Cancer
Thalidomide-O-amido-C3-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-128846A

Pomalidomide-C2-NH2 hydrochloride Cereblon Ligand-Linker Conjugates 15 hydrochloride	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.

HY-128846

Pomalidomide-C2-NH2 Cereblon Ligand-Linker Conjugates 15	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a PEG linker used in PROTAC technology.

HY-126458

Thalidomide-O-PEG2-propargyl E3 ligase Ligand-Linker Conjugates 32	E3 Ligase Ligand-Linker Conjugates Autophagy Apoptosis	Cancer
Thalidomide-O-PEG2-propargyl (E3 ligase Ligand-Linker Conjugates 32) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology . Thalidomide-O-PEG2-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-125846

(S,R,S)-AHPC-PEG1-OTs VH032-PEG1-OTs; VHL Ligand-Linker Conjugates 2; E3 ligase Ligand-Linker Conjugates 51	E3 Ligase Ligand-Linker Conjugates	Cancer
(S,R,S)-AHPC-PEG1-OTs is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 1-unit PEG linker used in PROTAC technology.

HY-125883

Pomalidomide-amido-C4-amido-PEG2-C2-NH-Boc Cereblon Ligand-Linker Conjugates 20; E3 Ligase Ligand-Linker Conjugates 53	E3 Ligase Ligand-Linker Conjugates	Cancer
Pomalidomide-amido-C4-amido-PEG2-C2-NH-Boc is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W007324

Maleimide	Alkaloids Microorganisms Pyrrole Alkaloids Other Alkaloids Source classification Endogenous metabolite Disease Research Fields Cancer	ADC Linker
Maleimide can be used for production of antibody-drug conjugate (ADC) which is used in cancer research. Maleimide also be leveraged for the preparation of fluorogenic probe, which is mainly used for the specific detection of thiol analytes .

HY-113162

Bovinic acid	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Bovinic acid is a conjugated linoleic acid with anticarcinogenic and anti-atherogenic activities.

HY-113293A

Estrone sulfate potassium 1 Publications Verification	Structural Classification Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Steroids Cancer	Endogenous Metabolite
Estrone sulfate potassium is a natural endogenous steroid and is an estrogen ester and conjugate .

HY-N1424

Glycoursodeoxycholic acid Ursodeoxycholylglycine	Structural Classification Microorganisms Source classification Endogenous metabolite Steroids	Endogenous Metabolite
Glycoursodeoxycholic acid, a acyl glycine and a bile acid-glycine conjugate, is a metabolite of ursodeoxycholic acid.

HY-122141

Glycohyocholic acid GHCA	Structural Classification Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite
Glycohyocholic acid(GHCA) is a glycine-conjugated form of the primary bile acid hyocholic acid .

HY-113427

trans-Vaccenic acid 1 Publications Verification	Structural Classification Animals Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
trans-Vaccenic acid is a precursor for the synthesis of saturated fatty acid in the rumen and of conjugated linoleic acid (CLA) at the tissue level.

HY-124422

Pentacosanoic acid	other families Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Plants Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Pentacosanoic acid is a 25-carbon long-chain saturated fatty acid. Pentacosanoic is a conjugate acid of a pentacosanoate .

HY-N1108

Uvedalin	Structural Classification Terpenoids Smallanthus uvedalia (Linnaeus) Mackenzie Source classification Diterpenoids Plants Compositae	Others
Uvedalin is a conjugated γ-lactone and oxygenated germacranolide that can be isolated from Polymnia uvedalia (L.) .

HY-141793

ATRA-biotin Biotin-ATRA-conjugate	Structural Classification Alkaloids Classification of Application Fields Other Alkaloids Source classification Endogenous metabolite Disease Research Fields Cancer	RAR/RXR PPAR Endogenous Metabolite Autophagy
ATRA-biotin (Biotin-ATRA-conjugate) is a biotin-conjugated ATRA. ATRA-biotin can be used to track ATRA in cells or a given tissue .

HY-N8252

Xanthoquinodin A1	Infection Quinones Microorganisms Classification of Application Fields Source classification Naphthalene Quinones Disease Research Fields	Antibiotic
Xanthoquinodin A1 is an anticoccidial antibiotic having a new xanthone-anthraquinone conjugate system .

HY-W020215

Tricarballylic acid	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Mitochondrial Metabolism Endogenous Metabolite
Tricarballylic acid, a conjugate acid of a tricarballylate, is a competitive inhibitor of the enzyme aconitate hydratase (aconitase; EC 4.2.1.3) with a K_i value of 0.52 mM .

HY-N1424R

Glycoursodeoxycholic acid (Standard)	Structural Classification Microorganisms Source classification Endogenous metabolite Steroids	Endogenous Metabolite
Glycoursodeoxycholic acid (Standard) is the analytical standard of Glycoursodeoxycholic acid. This product is intended for research and analytical applications. Glycoursodeoxycholic acid, a acyl glycine and a bile acid-glycine conjugate, is a metabolite of ursodeoxycholic acid.

HY-N0324

Cholic acid Maximum Cited Publications 7 Publications Verification	Structural Classification Human Gut Microbiota Metabolites Microorganisms Other disease Classification of Application Fields Source classification Disease markers Metabolic Disease Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite
Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. Cholic acid is orally active .

HY-N0324A

Cholic acid sodium Maximum Cited Publications 7 Publications Verification Sodium cholate	Structural Classification Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite
Cholic acid sodium is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. Cholic acid sodium is orally active .

HY-W034595

Eicosanedioic acid	Microorganisms Source classification	ADC Linker PROTAC Linkers
Eicosanedioic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Eicosanedioic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis

HY-117371

Hemiasterlin (-)-Hemiasterlin; Milnamide B	Alkaloids Structural Classification Classification of Application Fields Animals Marine natural products Sponge Disease Research Fields Indole Alkaloids Cancer	ADC Cytotoxin
Hemiasterlin ((-)-Hemiasterlin) is an antimitotic marine natural product with potent anticancer effcts. Hemiasterlin can be used as a cytotoxic payload (ADC Cytotoxin) in antibody-drug conjugates (ADCs) .

HY-N0324B

Cholic acid sodium hydrate	Source classification Endogenous metabolite Steroids	Endogenous Metabolite
Cholic acid sodium hydrate is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. Cholic acid sodium hydrate facilitates fat absorption and cholesterol excretion. Cholic acid sodium hydrate is orally active .

HY-77641

Cinnamoylglycine	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Cinnamoylglycine is a glycine conjugate of cinnamic acid and a urinary metabolite in human. Cinnamoylglycine is used as a potential urinary biomarker indicating intact or disrupted colonization resistance during and after antibiotic treatment .

HY-W041895

DL-Glutamic acid	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
DL-Glutamic acid is the conjugate acid of Glutamic acid, which acts as a fundamental metabolite. Comparing with the second phase of polymorphs α and β L-Glutamic acid, DL-Glutamic acid presents better stability .

HY-W034918

Docosanedioic acid	Structural Classification other families Classification of Application Fields Ketones, Aldehydes, Acids Source classification Plants Disease Research Fields Cancer	ADC Linker PROTAC Linkers
Docosanedioic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Docosanedioic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

HY-N1420A

Rhamnose monohydrate L-Rhamnose monohydrate	Structural Classification Microorganisms other families Classification of Application Fields Source classification Plants Disease Research Fields Saccharides Monosaccharides Cancer	Endogenous Metabolite
Rhamnose monohydrate (L-Rhamnose monohydrate) is a monosaccharide found in plants and bacteria. Rhamnose monohydrate-conjugated immunogens is used in immunotherapies . Rhamnose monohydrate crosses the epithelia via the transcellular pathway and acts as a marker of intestinal absorption .

HY-N6740

Beta-Zearalanol	Structural Classification Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Phenols Polyphenols Metabolic Disease Antibacterial Disease Research Disease Research Fields	Apoptosis
Beta-Zearalenol is an mycotoxin produced by Fusarium spp, which causes apoptosis and oxidative stress in mammalian reproductive cells . Beta-Zearalenol is the derivative of zearalenone (ZEA) which can conjugate with glucuronic acid .

HY-116374

Glycolithocholic acid Lithocholylglycine	Structural Classification Human Gut Microbiota Metabolites Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields Steroids	Endogenous Metabolite
Glycolithocholic acid (Lithocholylglycine), an endogenous metabolite, is a glycine-conjugated secondary bile acid. Glycolithocholic acid can be used to diagnose ulcerative colitis (UC), non-alcoholic steatohepatitis (NASH) and primary sclerosing cholangitis (PSC) .

HY-Y1055

Guanine 3 Publications Verification	Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Cancer	DNA/RNA Synthesis Endogenous Metabolite
Guanine is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds. Guanine has the potential to serve as a large-capacity N pool .

HY-121271

Kadsurin	Classification of Application Fields Source classification Lignans Phenylpropanoids Plants Schisandraceae Disease Research Fields Inflammation/Immunology Schisandra chinensis (Turcz.) Baill.	Others
Kadsurin, a natural compound from the stems of Kadsura heteroclita (Schizandraceae), results in significant decreases of CCL₄- induced lipid-peroxidation products, such as thiobarbituric acid reactive substances (TBA-RS), conjugated dienes and fluorescent products in the liver of mice .

HY-N7550

Latrunculin M	Structural Classification Natural Products Marine natural products Source classification Sponge	Others
Latrunculin M is a highly selective actin-macrolide conjugate that can be isolated from marine products. Latrunculin M can be converted from Latrunculin B, which can effectively induce actin depolymerization and is a good probe for detecting the actin skeleton.

HY-112942A

CMP-Sialic acid sodium salt CMP-Neu5Ac sodium salt	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
CMP-Sialic acid (CMP-Neu5Ac) sodium salt is an allosteric inhibitor of UDP-GlcNAc 2-epimerase. CMP-Sialic acid sodium salt provides a substrate for Golgi sialyltransferases. CMP-Sialic acid sodium salt is an important sugar nucleotide for biosynthesis of sialic acid and its conjugates .

HY-112942

CMP-Sialic acid CMP-Neu5Ac	Structural Classification Natural Products Human Gut Microbiota Metabolites Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
CMP-Sialic acid (CMP-Neu5Ac) is an allosteric inhibitor of UDP-GlcNAc 2-epimerase. CMP-Sialic acid provides a substrate for Golgi sialyltransferases. CMP-Sialic acid is an important sugar nucleotide for biosynthesis of sialic acid and its conjugates .

HY-113095

γ-CEHC	Structural Classification Monophenols Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Phenols Endogenous metabolite Disease Research Fields	Drug Metabolite Endogenous Metabolite
γ-CEHC is a γ-tocopherol (HY-N7148) metabolite. γ-CEHC is mainly excreted into the urine rather than into the bile. γ-CEHC is present in conjugated form in human urine, mainly as glucuronide .

HY-134544

Calendic acid	Structural Classification Ketones, Aldehydes, Acids Source classification Plants Compositae Millettia usaramensis Taub.	Others
Calendic acid (8(E),10(E),12(Z)-Octadecatrienoic acid) is a conjugated polyunsaturated fatty acid (PUFA) that can be isolated from C. officinalis seed oil. Calendic acid has anticancer activity .

HY-N7497

Protoescigenin	Triterpenes Structural Classification other families Classification of Application Fields Terpenoids Source classification Other Diseases Plants Disease Research Fields	Others
Protoescigenin is the main aglycone of horse chestnut saponin mixture known as escin. Protoescigenin is selected as substrate for exploratory chemistry towards selective protection, followed by propargyl ether formation and subsequent condensation with azido-monosaccharides, to obtain novel triazole linked conjugates of the triterpene .

HY-W751418

N-Nervonoyl taurine (Z)-2-tetracos-15-enamidoethanesulfonic acid	Structural Classification Natural Products Source classification Endogenous metabolite	FAAH
N-Nervonoyl taurine ((Z)-2-tetracos-15-enamidoethanesulfonic acid) is a fatty acid-taurine conjugate derived from nervonic acid. N-Nervonoyl taurine is a substrate of fatty acid amide hydrolase (FAAH) discovered during metabolite profiling .

HY-77641R

Cinnamoylglycine (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Endogenous Metabolite
Cinnamoylglycine (Standard) is the analytical standard of Cinnamoylglycine. This product is intended for research and analytical applications. Cinnamoylglycine is a glycine conjugate of cinnamic acid and a urinary metabolite in human. Cinnamoylglycine is used as a potential urinary biomarker indicating intact or disrupted colonization resistance during and after antibiotic treatment .

HY-125934

Allocholic acid	Structural Classification Microorganisms Classification of Application Fields Animals Source classification Disease Research Fields Steroids Cancer	Others
Allocholic acid is a typically fetal bile acid found in vertebrates and reappears during liver regeneration and carcinogenesis, besides it is also a conjugate acid of allocholate and an isomer of cholic acid. Allocholic acid is a potent and specific stimulant of the adult olfactory system, it has a role as a marine metabolite, a rat metabolite and a human metabolite .

HY-150524

UDP-Galactose	Structural Classification Natural Products Human Gut Microbiota Metabolites Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite P2Y Receptor
UDP-Galactose is a monosaccharide involved in nucleotide sugar metabolism. UDP-Galactose and its derivatives act as a natural agonist for G_i protein-conjugated P2Y₁₄ receptors in the immune system (IC₅₀=0.67 μM, hP2Y₁₄) .

HY-N1420AR

Rhamnose monohydrate (Standard)	Structural Classification Microorganisms other families Source classification Plants Saccharides Monosaccharides	Endogenous Metabolite
Rhamnose (monohydrate) (Standard) is the analytical standard of Rhamnose (monohydrate). This product is intended for research and analytical applications. Rhamnose monohydrate (L-Rhamnose monohydrate) is a monosaccharide found in plants and bacteria. Rhamnose monohydrate-conjugated immunogens is used in immunotherapies . Rhamnose monohydrate crosses the epithelia via the transcellular pathway and acts as a marker of intestinal absorption .

HY-113003

H-γ-Glu-Gln-OH γ-Glutamylglutamine; γ-Glu-Gln	Structural Classification Animals Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Others
H-γ-Glu-Gln-OH is a hydrophilic peptide and can be conjugated to drugs. The carrier composed of H-γ-Glu-Gln-OH has the characteristics of high water solubility and drug-loading capacity, good biocompatibility, low toxicity, improved tumor targeting ability, and anti-tumor efficacy .

HY-Y1055R

Guanine (Standard)	Structural Classification Natural Products Microorganisms Source classification Endogenous metabolite	DNA/RNA Synthesis Endogenous Metabolite
Guanine (Standard) is the analytical standard of Guanine. This product is intended for research and analytical applications. Guanine is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds. Guanine has the potential to serve as a large-capacity N pool .

HY-101884

Biocytin 2 Publications Verification (+)-Biocytin	Structural Classification Human Gut Microbiota Metabolites Microorganisms Neurological Disease Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Biocytin is a conjugate of _D-biotin and _L-lysine, where the carboxylate of _D-biotin is coupled with the ?-amine of _L-lysine via a secondary amide bond. Biocytin is a classical neuroanatomical tracer commonly used to map brain connectivity. Biocytin is used as a versatile marker in anterograde, retrograde and intracellular neuroanatomical investigations and in biotinidase assays .

HY-118667

Dehydroergosterol	Microorganisms Source classification	Liposome
Dehydroergosterolis a naturally occurring fluorescent sterol analog (Ex/Em=325/375 nm), which mimics the properties of cholesterol in cell membranes. DehydroergosterolEasily conjugated by cholesterol-binding proteins for real-time imaging in live cells. DehydroergosterolThe sterol environment and intracellular sterol transport in vivo can be probed/elucidated in real time .

HY-N7497R

Protoescigenin (Standard)	Triterpenes Structural Classification other families Terpenoids Source classification Plants	Others
Protoescigenin (Standard) is the analytical standard of Protoescigenin. This product is intended for research and analytical applications. Protoescigenin is the main aglycone of horse chestnut saponin mixture known as escin. Protoescigenin is selected as substrate for exploratory chemistry towards selective protection, followed by propargyl ether formation and subsequent condensation with azido-monosaccharides, to obtain novel triazole linked conjugates of the triterpene .

HY-111974

β-D-Glucopyranosyl abscisate ABA-GE; (S)-cis,trans-Abscisic acid glucosyl ester	Structural Classification other families Classification of Application Fields Terpenoids Sesquiterpenes Source classification Abscisic acid Phytohormone Plants Disease Research Fields Endocrinology Agricultural Research	Others
β-D-Glucopyranosyl abscisate (ABA-GE) is a hydrolyzable abscisic acid (ABA) conjugate that accumulates in the vacuole and presumably also in the endoplasmic reticulum. The deconjugation of β-D-Glucopyranosyl abscisate allows the rapid formation of free ABA in response to abiotic stress conditions such as dehydration and salt stress. β-D-Glucopyranosyl abscisate contributes to the maintenance of ABA homeostasis .

HY-N11420

Coronatine	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Disease Research Fields Agricultural Research	Bacterial
Coronatine is a plant growth regulator produced by Pseudomonas syringae. Coronatine simulates bioactive jasmonic acid (HY-122464A) conjugates or octadecanoid signal molecules of higher plants to make plants appear pathogenic symptoms. Coronatine promotes the virulence of Pseudomonas syringae in plants by activating the signal cascade that inhibits the accumulation of Salicylic acid (HY-B0167) .

HY-121619

Jacaric acid	Structural Classification Caprifoliaceae Ketones, Aldehydes, Acids Source classification Plants Centranthus ruber (L.) DC	Apoptosis
Jacaric acid is a conjugated linolenic acid, which inhibits viability in cells PC-3 (IC₅₀ is 11.8 μM), LNCaP (IC₅₀ is 2.2 μM) and DLD-1, induces apoptosis and necrosis . Jacaric acid exhibits anticaner activity against prostate cancer and adenocarcinoma . Jacaric acid exhibits immunomodulating activity in murine peritoneal macrophages as an immunopotentiator . Jacaric acid is orally active.

HY-121624

Anthglutin	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Glutathione S-transferase
Anthglutin is a gamma-glutamyltransferase inhibitor isolated from Penicillium oxalicum cultures. The Ki values ??of Anthglutin for different enzymes are: porcine kidney enzyme 5.7 μM, human kidney enzyme 18.3 μM, human liver soluble enzyme 13.6 μM, and conjugated enzyme 10.2 μM. Anthglutin had no significant effect on intestinal absorption of methionine in rats .

HY-139066

Punicic acid Trichosanic acid	Structural Classification Punica granatum L. Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Punicaceae Plants Disease Research Fields	TNF Receptor GLUT Proteasome Tau Protein PKC
Punicic acid is a bioactive compound of pomegranate seed oil. Punicic acid is an isomer of conjugated α-linolenic acid and ω-5 polyunsaturated fatty acids. Punicic acid has anti-inflammatory and antioxidant activities and can inhibit the expression of inflammatory mediators such as tumor necrosis factor α (TNF-α). Punicic acid can also reduce the formation of β-amyloid deposits and hyperphosphorylation of tau by increasing the expression of GLUT4 protein and inhibiting the overactivation of calpain, and is used to prevent and treat neurodegenerative diseases. In addition, punicic acid also has breast cancer inhibitor properties that depend on lipid peroxidation and PKC pathways .

HY-W012952R

(2E,4E)-Hepta-2,4-dienal (Standard)	Structural Classification Natural Products Vaccinium macrocarpon Aiton Source classification Ericaceae Plants	Biochemical Assay Reagents
(2E,4E)-Hepta-2,4-dienal (Standard) is the analytical standard of (2E,4E)-Hepta-2,4-dienal. This product is intended for research and analytical applications. (2E,4E)-Hepta-2,4-dienal is a naturally occurring organic compound that belongs to the group of aldehydes. It is an unsaturated aldehyde with two conjugated double bonds, giving it unique chemical and physical properties. (2E,4E)-Hepta-2,4-dienal is commonly found in various plant sources, especially in spices such as parsley and coriander. It is used as a flavoring agent and food additive in the formulation of various foods such as baked goods, snacks and beverages. It is also used in the fragrance industry, especially in the production of perfume and cologne.

Cat. No.	Product Name	Chemical Structure

HY-145989S

Aminobenzenesulfonic auristatin E-d8
Aminobenzenesulfonic auristatin E-d₈ is the deuterium labeled Aminobenzenesulfonic auristatin E. Aminobenzenesulfonic auristatin E is a drug-linker conjugate for ADC. Aminobenzenesulfonic auristatin E has potent antitumor activity by using Auristatin E (a cytotoxic tubulin modifier), linked via the ADC linker Aminobenzenesulfonic[1][2].

HY-18569S

3-Indoleacetic acid-d5 1 Publications Verification
3-Indoleacetic acid-d₅ is the deuterium labeled 3-Indoleacetic acid. 3-Indoleacetic acid-d₅ can be used as internal standard for assay of IAA releases by alkaline hydrolysis of ester and amide conjugates[1].

HY-N0324S

Cholic acid-d4
Cholic acid-d₄ is the deuterium labeled Cholic acid. Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion.

HY-N0324S1

Cholic acid-d5
Cholic acid-d₅ is the deuterium labeled Cholic acid. Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion.

HY-N0324S2

Cholic acid-13C
Cholic acid- ¹³C is the ¹³C-labeled Cholic acid. Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion.

HY-N1424S

Glycoursodeoxycholic Acid-d4
Glycoursodeoxycholic acid-d4 (Ursodeoxycholylglycine-d4) is the deuterium labeled Glycoursodeoxycholic acid. Glycoursodeoxycholic acid, a acyl glycine and a bile acid-glycine conjugate, is a metabolite of ursodeoxycholic acid[1][2].

HY-15575S

VcMMAE-d8
VcMMAE-d8 is an isotope of VcMMAE (HY-15575). VcMMAE-d8 is a *agent-linker conjugate* for ADC** with potent antitumor activity by using the anti-mitotic agent, monomethyl auristatin E (MMAE, a tubulin inhibitor), linked via the lysosomally cleavable dipeptide, valine-citrulline (vc) .

HY-15583S

Auristatin F-d8
Auristatin F-d₈ is deuterium labeled Auristatin F (HY-15583). Auristatin F is a potent cytotoxin in antibo-conjugated agents and an analogue of MMAF. Auristatin F is a potent microtubule inhibitor and vascular damaging agent (VDA). Auristatin F inhibits cell division by preventing tubulin aggregation.Auristatin F can be used in antibody-drug conjugates (ADC) .

HY-N1420AS

Rhamnose-13C monohydrate
Rhamnose- ¹³C (monohydrate) is the ¹³C labeled Rhamnose monohydrate. Rhamnose monohydrate (L-Rhamnose monohydrate) is a monosaccharide found in plants and bacteria. Rhamnose monohydrate-conjugated immunogens is used in immunotherapies. Rhamnose monohydrate c

HY-N1420AS2

Rhamnose-13C-2 monohydrate
Rhamnose- ¹³C-2 (monohydrate) is the ¹³C labeled Rhamnose monohydrate. Rhamnose monohydrate (L-Rhamnose monohydrate) is a monosaccharide found in plants and bacteria. Rhamnose monohydrate-conjugated immunogens is used in immunotherapies. Rhamnose monohydrate

HY-12454S

DM4-d6
DM4-d₆ is deuterium labeled DM4. DM4 is is an antitubulin agent that inhibit cell division. DM4 can be used in the preparation of antibody agent conjugate.

HY-77641S

Cinnamoylglycine-d2
Cinnamoylglycine-d₂ is the deuterium labeled Cinnamoylglycine. Cinnamoylglycine is a glycine conjugate of cinnamic acid and a urinary metabolite in human. Cinnamoylglycine is used as a potential urinary biomarker indicating intact or disrupted colonization resistance during and after antibiotic treatment[1].

HY-13631DS

Dxd-d5
Dxd-d₅ is a deuterium labeled Dxd. Dxd is a potent DNA topoisomerase I inhibitor, with an IC50 of 0.31 μM, used as a conjugated drug of HER2-targeting ADC (DS-8201a) [1].

HY-W019776

Sudan I-d5
Sudan I-d₅ is a the deuterated Sudan I. Sudan I is a diazo-conjugate red dye and can be used as an additive to products such as oils, solvents or polishes. Sudan I inhibits growth of bacterial strains Clostridium perfringens and L. rhamnosus[1].

HY-Y1055S

Guanine-13C
Guanine- ¹³C is the ¹³C labeled Guanine[1]. Guanine (2-Aminohypoxanthine) is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds.

HY-116374S

Glycolithocholic acid-d4
Glycolithocholic acid-d₄ is the deuterium labeled Glycolithocholic acid. Glycolithocholic acid, an endogenous metabolite, is a glycine-conjugated secondary bile acid and can be used to diagnose ulcerative colitis (UC), non-alcoholic steatohepatitis (NASH) and primary sclerosing cholangitis (PSC) [1][2][3][4].

HY-W041895S

DL-Glutamic acid-d5
DL-Glutamic acid-d₅ is the deuterium labeled DL-Glutamic acid. DL-Glutamic acid is the conjugate acid of Glutamic acid, which acts as a fundamental metabolite. Comparing with the second phase of polymorphs α and β L-Glutamic acid, DL-Glutamic acid presents better stability[1].

HY-Y1055S3

Guanine-15N5
Guanine- ¹⁵N₅ is ¹⁵N labeled Guanine (HY-Y1055). Guanine (2-Aminohypoxanthine) is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds.

HY-13631ES4

Deruxtecan-d5
Deruxtecan-d₅ is deuterium labeled Deruxtecan (HY-13631E). Deruxtecan is an ADC drug-linker conjugate composed of an DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402.

HY-Y1055S4

Guanine-13C5
Guanine- ¹³C₅ is ¹³C-labeled Guanine (HY-Y1055). Guanine (2-Aminohypoxanthine) is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds.

HY-13631ES

Deruxtecan-d4
Deruxtecan-d₄ is deuterium labeled Deruxtecan (HY-13631E). Deruxtecan is an ADC drug-linker conjugate composed of an DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402.

HY-Y1055S1

Guanine-13C,15N2
Guanine- ¹³C, ¹⁵N₂ is the ¹³C and ¹⁵N labeled Guanine[1]. Guanine (2-Aminohypoxanthine) is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds.

HY-114360AS1

Taurohyodeoxycholic acid-d4 sodium
Taurohyodeoxycholic acid-d4 (sodium) is a deuterated labeled Taurohyodeoxycholic acid (sodium) . Taurohyodeoxycholic acid (THDCA) sodium is the taurine-conjugated form of the secondary bile acid hyodeoxycholic acid. Taurohyodeoxycholic acid can also reduce the activity and expression of myeloperoxidase TNF-α and IL-6, as well as colonic damage in TNBS-induced ulcerative colitis mouse model.

HY-Y1055S2

Guanine-13C5,15N5
Guanine- ¹³C₅, ¹⁵N₅ is ¹³C and ¹⁵N-labeled Guanine (HY-Y1055). Guanine (2-Aminohypoxanthine) is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds.

HY-N6740S

β-Zearalanol-d4
β-Zearalanol-d₄ is a deuterium labeled Beta-Zearalanol (HY-N6740） . Beta-Zearalenol is an mycotoxin produced by Fusarium spp, which causes apoptosis and oxidative stress in mammalian reproductive cells . Beta-Zearalenol is the derivative of zearalenone (ZEA) which can conjugate with glucuronic acid .

HY-145397S

(4-NH2)-Exatecan-d5
(4-NH2)-Exatecan-d5 is a deuterated labeled (4-NH2)-Exatecan . (4-NH2)-Exatecan (compound A), a topoisomerase inhibitor, is a derivative of Exatecan. (4-NH2)-Exatecan can be used in the synthesis of antibody-drug conjugates (ADCs) .

HY-114816S

N-butyryl-L-Homoserine lactone-d5

N-butyryl-L-Homoserine lactone-d₅ is the deuterium labeled N-Butanoyl-L-homoserine lactone. N-Butanoyl-L-homoserine lactone (C4-HSL) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Butanoyl-L-homoserine lactone has antibacterial activity and is used in antibacterial biofilm[1]. N-Butanoyl-L-homoserine lactone aptamers blocks qurom sensing and inhibits biofilm formation in Pseudomonas aeruginosa[2][3].

HY-161022S1

FL118-C3-O-C-amide-C-NH2-d5 formate
FL118-C3-O-C-amide-C-NH2-d5 formate is a deuterium labeled FL118-C3-O-C-amide-C-NH2 formate. FL118-C3-O-C-amide-C-NH2 formate is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

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