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Carbamazepine 10,11 epoxide-d<sub>2</sub>

" in MedChemExpress (MCE) Product Catalog:

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By Research Areas:	Cancer (758) Cardiovascular Disease (240) Endocrinology (188) Infection (397) Inflammation/Immunology (354) Metabolic Disease (369) Neurological Disease (405)
Click Chemistry:	Azide (2) Alkynes (14)
Oligonucleotides:	Pre-designed siRNA Sets (1) Cholesterol (1) siRNAs (1)

3115

Inhibitors & Agonists

Screening Libraries

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Biochemical Assay Reagents

Peptides

MCE Kits

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Recombinant Proteins

2911

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Oligonucleotides

Targets Recommended: Epoxide Hydrolase P-glycoprotein

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W013378S1

Carbamazepine 10,11 epoxide-d10	Endogenous Metabolite	Others
Carbamazepine 10,11 epoxide-d₁₀ is the deuterium labeled Carbamazepine 10,11 epoxide[1].

HY-W013378

**Carbamazepine 10,11-epoxide**	Endogenous Metabolite	Neurological Disease
Carbamazepine 10,11-epoxide is an orally active metabolite of Carbamazepine (HY-B0246). Carbamazepine has anticonvulsant effect. Carbamazepine can be used for the research of seizures .

HY-W013378S

Carbamazepine 10,11 epoxide-d2	Endogenous Metabolite Isotope-Labeled Compounds	Others
Carbamazepine 10,11 epoxide-d₂ is the deuterium labeled Carbamazepine 10,11 epoxide[1]. Carbamazepine 10,11-epoxide is an orally active metabolite of Carbamazepine (HY-B0246). Carbamazepine has anticonvulsant effect. Carbamazepine can be used for the research of seizures[2].

HY-W013378R

Carbamazepine 10,11-epoxide (Standard)	Endogenous Metabolite	Neurological Disease
Carbamazepine 10,11-epoxide (Standard) is the analytical standard of Carbamazepine 10,11-epoxide. This product is intended for research and analytical applications. Carbamazepine 10,11-epoxide is an orally active metabolite of Carbamazepine (HY-B0246). Carbamazepine has anticonvulsant effect. Carbamazepine can be used for the research of seizures .

HY-W013378S2

Carbamazepine 10,11-epoxide-13C,d2	Endogenous Metabolite	Others
Carbamazepine 10,11-epoxide- ¹³C,d₂ is the deuterium labeled Carbamazepine 10,11-epoxide-C13. Carbamazepine 10,11-epoxide-C13 is a ¹³C-labled Carbamazepine 10,11-epoxide. Carbamazepine 10,11-epoxide is an orally active metabolite of Carbamazepine (HY-B0246). Carbamazepine has anticonvulsant effect. Carbamazepine can be used for the research of seizures[1][2].

HY-W013378S4

Carbamazepine 10,11-epoxide-13C	Isotope-Labeled Compounds	Others
Carbamazepine 10,11-epoxide- ¹³C is the ¹³C labeled Carbamazepine 10,11-epoxide (HY-W013378)[1].

HY-W013378S5

Carbamazepine 10,11-epoxide-13C-1	Isotope-Labeled Compounds	Others
Carbamazepine 10,11-epoxide- ¹³C-1 is the ¹³C labeled Carbamazepine 10,11-epoxide (HY-W013378)[1].

HY-W013378S3

Carbamazepine 10,11-epoxide-13C-15N	Isotope-Labeled Compounds	Others
Carbamazepine 10,11-epoxide- ¹³C, ¹⁵N is the ¹³C and ¹⁵N labeled Carbamazepine 10,11-epoxide (HY-W013378)[1].

HY-B0246S1

Carbamazepine-d2 CBZ-d<sub>2sub>; NSC 169864-d<sub>2sub>	Isotope-Labeled Compounds Sodium Channel Autophagy Mitophagy	Neurological Disease Cancer
Carbamazepine-d₂ is the deuterium labeled Carbamazepine. Carbamazepine, a sodium channel blocker, is an anticonvulsant agent.

HY-138969

*(±)10(11)-EDP ethanolamide* 10,11-EDP-EA; 10,11-EDP epoxide; 10,11-Epoxy docosapentaenoic ethanolamide	Others	Others
(±)10(11)-EDP ethanolamide (10,11-EDP-EA) (compound C) is an ω-3 endocannabinoid epoxide derivative with antiangiogenic, antitumor and anti-migratory properties in osteosarcoma models.

HY-N12528

10,11-EDT	Epoxide Hydrolase	Cardiovascular Disease
10,11-EDT, a soluble epoxide hydrolase (sEH) substrate, is a metabolic product of adrenic acid. 10,11-EDT is an endothelium-derived hyperpolarizing factor with strong vasorelaxant effects .

HY-126041A

*(±)10(11)-EpDPA* (±)10,11-EDP; (±)10,11-EpDPE; (±)10,11-Epoxy docosapentaenoic acid	Epoxide Hydrolase	Metabolic Disease
(±)10(11)-EpDPA, a docosahexaenoic acid epoxygenase metabolite, acts as a substrate for soluble epoxide hydrolase (sEH) with a K_m value of 5.1 µM for human sEH .

HY-W653882

Carbamazepine-d2,15N CBZ-d<sub>2sub>,¹⁵N; NSC 169864-d<sub>2sub>,¹⁵N	Isotope-Labeled Compounds	Others
Carbamazepine-d2,15N is a deuterated labeled Carbamazepine-d2,15N .

HY-B2124R

10,11-Dihydrocarbamazepine (Standard)	Drug Metabolite	Neurological Disease
10,11-Dihydrocarbamazepine (Standard) is the analytical standard of 10,11-Dihydrocarbamazepine. This product is intended for research and analytical applications. 10,11-Dihydrocarbamazepine is the active metabolite of Oxcarbazepine. 10,11-Dihydrocarbamazepine also is an intermediate. Oxcarbazepine is rapidly and almost completely converted to 10,11-Dihydrocarbamazepine with probable Anticonvulsant efficacy .

HY-B2124

10,11-Dihydrocarbamazepine	Drug Metabolite	Neurological Disease
10,11-Dihydrocarbamazepine is the active metabolite of Oxcarbazepine. 10,11-Dihydrocarbamazepine also is an intermediate. Oxcarbazepine is rapidly and almost completely converted to 10,11-Dihydrocarbamazepine with probable Anticonvulsant efficacy .

HY-N6679A

10,11-Dehydrocurvularin	HSP TGF-beta/Smad	Infection Cancer
10,11-Dehydrocurvularin is a prevalent fungal phytotoxin and an antibiotic. 10,11-Dehydrocurvularin is a strong activator of the heat shock response. 10,11-Dehydrocurvularin inhibits TGF-β signalling pathway. Anti-tumorous activity ^[2].

HY-N10214

*(-)-10,11-Dihydroxyfarnesol*	NO Synthase	Inflammation/Immunology
(-)-10,11-Dihydroxyfarnesol is a compound isolated from an endolichenic fungus Cryptomarasmius aucubae. (–)-10,11-Dihydroxyfarnesol significantly inhibits nitric oxide (NO) production .

HY-B0246S4

Carbamazepine-d4 CBZ-d<sub>4sub>; NSC 169864-d<sub>4sub>	Isotope-Labeled Compounds	Others
Carbamazepine-d4 (CBZ-d4; NSC 169864-d4) is the deuterium labeled Carbamazepine-d4 (HY-B0246S4) .

HY-113164S

*Vitamin K1 2,3-epoxide-d7*	Isotope-Labeled Compounds	Others
Vitamin K1 2,3-epoxide-d₇ is the deuterium labeled Vitamin K1 2,3-epoxide[1].

HY-133971S

*Cholesterol-5α,6α-epoxide-d7*	Isotope-Labeled Compounds	Others
Cholesterol-5α,6α-epoxide-d₇ is deuterium labeled Cholesterol-5α,6α-epoxide.

HY-139391

*(±)10(11)-DiHDPA*	Others	Others
(±)10(11)-DiHDPA is a fatty acid diol and a metabolite of epoxidized fatty acids (EpFAs) .

HY-N6679

*(R)-10,11-Dehydrocurvularin*	Antibiotic	Cancer
(R)-10,11-Dehydrocurvularin is a secondary metabolite isolated from Curvularia sp.. (R)-10,11-Dehydrocurvularin displays concentration-dependent cytotoxicity towards human tumor cell lines with a mean IC₅₀ value of 1.25 µM .

HY-156756S

*7-Hydroxymethyl-10,11-MDCPT-d5*	Isotope-Labeled Compounds ADC Cytotoxin	Others
7-Hydroxymethyl-10,11-MDCPT-d₅ is deuterium labeled 7-Hydroxymethyl-10,11-MDCPT, which is a is a payload that can be used for ADC synthesis .

HY-156756

*7-Hydroxymethyl-10,11-MDCPT*	ADC Cytotoxin	Others
7-Hydroxymethyl-10,11-MDCPT is a payload that can be used for ADC synthesis .

HY-RS13999

SUB1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SUB1 Human Pre-designed siRNA Set A contains three designed siRNAs for SUB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SUB1 Human Pre-designed siRNA Set A SUB1 Human Pre-designed siRNA Set A

HY-146227

DNA topoisomerase II inhibitor 1	Topoisomerase Apoptosis	Cancer
DNA topoisomerase II inhibitor 1 (compound 8ed) is a potent DNA topoisomerase II inhibitor. DNA topoisomerase II inhibitor 1 shows anti-proliferative activity. DNA topoisomerase II inhibitor 1 induces apoptosis and cell cycle arrest at sub G1 phase .

HY-B0246R

Carbamazepine (Standard)	Sodium Channel Autophagy Mitophagy Potassium Channel Calcium Channel HDAC	Neurological Disease Cancer
Carbamazepine (Standard) is the analytical standard of Carbamazepine. This product is intended for research and analytical applications. Carbamazepine is an orally active pressure-sensitive sodium ion channel blocker with an IC₅₀ of 131 μM. Carbamazepine blocks voltage gated Na ⁺, Ca ²⁺, and K ⁺ channels, and is also a HDAC inhibitor (IC₅₀: 2 μM). Carbamazepine is an anticonvulsant and can be used for research of epilepsy and neuropathic pain ^[2] .

HY-N8888

10,11-Dihydro-24-hydroxyaflavinine	Others	Others
10,11-Dihydro-24-hydroxyaflavinine (10,23,24,25-tetrahydro-24-hydroxyaflavinine), an aflavinine analog, is a natural product that can be isolated from Ascostromata of Eupenicillium crustaceum .

HY-116766

ACEA1011	Others	Others
ACEA1011 is an active compound.

HY-15792

(R)-FL118 10,11-(Methylenedioxy)-20(R)-camptothecin	Others	Cancer
(R)-FL118 (10,11-(Methylenedioxy)-20(R)-camptothecin) is the R-enantiomer of FL118 (HY-12486). (R)-FL118 shows anticancer activity .

HY-122079

NSC1011	Others	Cancer
NSC1011 is a potent Ras converting enzyme 1 endoprotease (Rce1) inhibitor with an IC₅₀ value of 6.9 µM for HsRce1 (crystal structure of the human Rce1). NSC1011 induces mislocalizing EGFR-H-Ras, EGFR-N-Ras, and EGFR-K-Ras .

HY-B0246

*Carbamazepine* 10+ Cited Publications CBZ; NSC 169864	Sodium Channel Autophagy Mitophagy Potassium Channel Calcium Channel HDAC	Neurological Disease Cancer
Carbamazepine is an orally active pressure-sensitive sodium ion channel blocker with an IC₅₀ of 131 μM. Carbamazepine blocks voltage gated Na ⁺, Ca ²⁺, and K ⁺ channels, and is also a HDAC inhibitor (IC₅₀: 2 μM). Carbamazepine is an anticonvulsant and can be used for research of epilepsy and neuropathic pain ^[2] .

HY-12486

FL118 10,11-(Methylenedioxy)-20(S)-camptothecin	Survivin Apoptosis IAP	Cancer
FL118 (10,11-(Methylenedioxy)-20(S)-camptothecin), a Camptothecin (HY-16560) analogue, is a potent and orally active survivin inhibitor. FL118 binds to oncoprotein DDX5 (p68) to dephosphorylates and degrades DDX5. FL118 can be used for the research of cancer ^[2].

HY-10844S1

Pretomanid-d5 PA-824-d<sub>5sub>; (S)-PA 824-d<sub>5sub>	Antibiotic Bacterial Isotope-Labeled Compounds	Infection Cancer
Pretomanid-d₅ is deuterated labeled Pretomanid (HY-10844). Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 μg/mL.

HY-161643

S21-1011	Cholinesterase (ChE) Keap1-Nrf2	Neurological Disease Inflammation/Immunology
S21-1011 is a selective inhibitor for butyrylcholinesterase (BChE), with IC₅₀ of 0.059 and 0.162 μM, for eqBChE and hBChE, respectively. S21-1011 exhibits good blood-brain barrier (BBB) permeability and good pharmacokinetic characters. S21-1011 exhibits anti-inflammatory activity through activation of *keap1-Nrf2-ARE* pathway (EC₅₀ is 23.48 μM for antioxidant element ARE activation), ameliorates cognitive impairment in murine Alzheimer’s disease model .

HY-42034

Hydroquinine Dihydroquinine	Others	Inflammation/Immunology
Hydroquinine is a cinchona alkaloid, can be used in the preparation of its derivatives such as C9 epihydroquinine, 9-acetoxy-10,11-dihydroquinine and 10,11-dihydroquinine monohydrochloride .

HY-13215

Avasimibe 5+ Cited Publications CI-1011; PD-148515	Acyltransferase	Cancer
Avasimibe (CI-1011; PD-148515) is an orally active acyl coenzyme A-cholesterol acyltransferase (ACAT; also called SOAT)) inhibitor with IC₅₀s of 24 and 9.2 µM for ACAT1 and *ACAT2*, respectively . Avasimibe can be used for the research of prostate cancer ^[2].

HY-106168

Thymectacin NB1011	Others	Cancer
Thymectacin (NB1011) is an agent selectively targeting tumor cells that have a high expression of thymidylate synthase (TS). Thymectacin is an aryloxy phosphoramidate derivative of BVdU (brivudin) ^[2].

HY-B0246S3

Carbamazepine-(Ph)d8 CBZ-(Ph)d8; NSC 169864-(Ph)d8	Isotope-Labeled Compounds	Neurological Disease Cancer
Carbamazepine-(Ph)d8 (CBZ-(Ph)d8; NSC 169864-(Ph)d8) is the deuterium labeled Carbamazepine-(Ph) (HY-B0246) .

HY-42034R

Hydroquinine (Standard)	Others	Inflammation/Immunology
Hydroquinine (Standard) is the analytical standard of Hydroquinine. This product is intended for research and analytical applications. Hydroquinine is a cinchona alkaloid, can be used in the preparation of its derivatives such as C9 epihydroquinine, 9-acetoxy-10,11-dihydroquinine and 10,11-dihydroquinine monohydrochloride .

HY-B0389S26

D-Glucose-d2-2 Glucose-d<sub>2sub>-2; D-(+)-Glucose-d<sub>2sub>-2; Dextrose-d<sub>2sub>-2	Endogenous Metabolite	Metabolic Disease Cancer
D-Glucose-d₂-2 is the deuterium labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling mol

HY-Y0418S4

Dulcite-d2 Dulcitol-d<sub>2sub>; Melampyrit-d<sub>2sub>; NSC 1944-d<sub>2sub>	Isotope-Labeled Compounds Endogenous Metabolite	Others
Dulcite-d₂ is the deuterium labeled Dulcite. Dulcite is a sugar alcohol with a slightly sweet taste which is a metabolic breakdown product of galact[1][2].

HY-B0400S9

D-Sorbitol-d2-2 Sorbitol-d<sub>2sub>-2; D-Glucitol-d<sub>2sub>-2	Endogenous Metabolite	Others
D-Sorbitol-d₂-2 is the deuterium labeled D-Sorbitol. D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and di

HY-B0389S5

D-Glucose-d2 Glucose-d<sub>2sub>; D-(+)-Glucose-d<sub>2sub>; Dextrose-d<sub>2sub>	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
D-Glucose-d₂2 is the deuterium labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].

HY-B0141AS1

Alpha-Estradiol-d2 Alfatradiol-d<sub>2sub>; Epiestradiol-d<sub>2sub>; Epiestrol-d<sub>2sub>	5 alpha Reductase Endogenous Metabolite	Cardiovascular Disease Metabolic Disease
Alpha-Estradiol-d₂ is the deuterium labeled Alpha-Estradiol. Alpha-Estradiol is a weak estrogen and a 5α-reductase inhibitor which is used as a topical medication in the treatment of androgenic alopecia[1].

HY-B0389S22

D-Glucose-13C2,d2 Glucose-¹³C<sub>2sub>,d<sub>2sub>; D-(+)-Glucose-¹³C<sub>2sub>,d<sub>2sub>; Dextrose-¹³C<sub>2sub>,d<sub>2sub>	Endogenous Metabolite	Metabolic Disease Cancer
D-Glucose- ¹³C₂,d₂ is the deuterium and ¹³C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical si

HY-125833

Alpha-Naphthoflavone 5+ Cited Publications	Cytochrome P450 Aryl Hydrocarbon Receptor Apoptosis	Cancer
Alpha-Naphthoflavone is an orally active flavonoid that is a potent, competitive inhibitor of aromatase< b>aromatase. < b > IC < sub > 50 < / sub > < / b > and < b > K < sub > I < / sub > < / b > value were 0.5 and 0.2 microns. Alpha-Naphthoflavone can inhibit cell proliferation and induce apoptosis ^[2] .

HY-107542S2

Oleoylethanolamide-d2 N-Oleoylethanolamide-d<sub>2sub>; Oleamide MEA-d<sub>2sub>; Oleic acid monoethanolamide-d<sub>2sub>	Isotope-Labeled Compounds Endogenous Metabolite PPAR	Cardiovascular Disease Metabolic Disease
Oleoylethanolamide-d₂ is the deuterium labeled Oleoylethanolamide. Oleoylethanolamide is a high affinity endogenous PPAR-α agonist, which plays an important role in the treatment of obesity and arteriosclerosis.

HY-77839S1

Cortodoxone-d2 11-Deoxycortisol-d<sub>2sub>; cortexolone-d<sub>2sub>; Reichstein's substance S-d<sub>2sub>	Isotope-Labeled Compounds Glucocorticoid Receptor Endogenous Metabolite	Inflammation/Immunology Endocrinology
Cortodoxone-d₂ is the deuterium labeled Cortodoxone. Cortodoxone is a glucocorticoid steroid hormone that can be oxygenated to cortisol (Hydrocortisone)[1].

HY-B0511S2

Biotin-d2 Vitamin B7-d<sub>2sub>; Vitamin H-d<sub>2sub>; D-Biotin-d<sub>2sub>	Endogenous Metabolite	Metabolic Disease
Biotin-d₂ is the deuterium labeled Biotin. Biotin is an enzyme co-factor present in minute amounts in every living cell.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W013378

**Carbamazepine 10,11-epoxide**	Structural Classification Alkaloids Neurological Disease Classification of Application Fields Other Alkaloids Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Carbamazepine 10,11-epoxide is an orally active metabolite of Carbamazepine (HY-B0246). Carbamazepine has anticonvulsant effect. Carbamazepine can be used for the research of seizures .

HY-N6679A

10,11-Dehydrocurvularin	Infection Structural Classification Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Phenols Polyphenols Disease Research Anticancer Disease Research Fields	HSP TGF-beta/Smad
10,11-Dehydrocurvularin is a prevalent fungal phytotoxin and an antibiotic. 10,11-Dehydrocurvularin is a strong activator of the heat shock response. 10,11-Dehydrocurvularin inhibits TGF-β signalling pathway. Anti-tumorous activity ^[2].

HY-42034

Hydroquinine Dihydroquinine	Alkaloids Structural Classification Classification of Application Fields Source classification Rubiaceae Cinchona calisaya Wedd. Quinoline Alkaloids Plants Inflammation/Immunology Disease Research Fields	Others
Hydroquinine is a cinchona alkaloid, can be used in the preparation of its derivatives such as C9 epihydroquinine, 9-acetoxy-10,11-dihydroquinine and 10,11-dihydroquinine monohydrochloride .

HY-125833

Alpha-Naphthoflavone 5+ Cited Publications	Flavonoids Flavones Source classification Indigofera heterantha Wall. ex Brand. Plants Compositae Disease Research Fields Cancer	Cytochrome P450 Aryl Hydrocarbon Receptor Apoptosis
Alpha-Naphthoflavone is an orally active flavonoid that is a potent, competitive inhibitor of aromatase< b>aromatase. < b > IC < sub > 50 < / sub > < / b > and < b > K < sub > I < / sub > < / b > value were 0.5 and 0.2 microns. Alpha-Naphthoflavone can inhibit cell proliferation and induce apoptosis ^[2] .

HY-W013378R

Carbamazepine 10,11-epoxide (Standard)	Structural Classification Alkaloids Other Alkaloids Source classification Endogenous metabolite	Endogenous Metabolite
Carbamazepine 10,11-epoxide (Standard) is the analytical standard of Carbamazepine 10,11-epoxide. This product is intended for research and analytical applications. Carbamazepine 10,11-epoxide is an orally active metabolite of Carbamazepine (HY-B0246). Carbamazepine has anticonvulsant effect. Carbamazepine can be used for the research of seizures .

HY-N12528

10,11-EDT	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Epoxide Hydrolase
10,11-EDT, a soluble epoxide hydrolase (sEH) substrate, is a metabolic product of adrenic acid. 10,11-EDT is an endothelium-derived hyperpolarizing factor with strong vasorelaxant effects .

HY-N10214

*(-)-10,11-Dihydroxyfarnesol*	Structural Classification Microorganisms Classification of Application Fields Terpenoids Sesquiterpenes Source classification Inflammation/Immunology Disease Research Fields	NO Synthase
(-)-10,11-Dihydroxyfarnesol is a compound isolated from an endolichenic fungus Cryptomarasmius aucubae. (–)-10,11-Dihydroxyfarnesol significantly inhibits nitric oxide (NO) production .

HY-N6679

*(R)-10,11-Dehydrocurvularin*	Structural Classification Classification of Application Fields Source classification Antibacterial Disease Research Microorganisms Macrolide Antibiotics Antibiotics Phenols Polyphenols Anticancer Disease Research Fields Cancer	Antibiotic
(R)-10,11-Dehydrocurvularin is a secondary metabolite isolated from Curvularia sp.. (R)-10,11-Dehydrocurvularin displays concentration-dependent cytotoxicity towards human tumor cell lines with a mean IC₅₀ value of 1.25 µM .

HY-N8888

10,11-Dihydro-24-hydroxyaflavinine	Natural Products Animals Source classification	Others
10,11-Dihydro-24-hydroxyaflavinine (10,23,24,25-tetrahydro-24-hydroxyaflavinine), an aflavinine analog, is a natural product that can be isolated from Ascostromata of Eupenicillium crustaceum .

HY-42034R

Hydroquinine (Standard)	Alkaloids Structural Classification Source classification Rubiaceae Cinchona calisaya Wedd. Quinoline Alkaloids Plants	Others
Hydroquinine (Standard) is the analytical standard of Hydroquinine. This product is intended for research and analytical applications. Hydroquinine is a cinchona alkaloid, can be used in the preparation of its derivatives such as C9 epihydroquinine, 9-acetoxy-10,11-dihydroquinine and 10,11-dihydroquinine monohydrochloride .

HY-N13484

*1,2-Methylenedioxy-3,10,11-trimethoxynoraporphine*	Structural Classification Alkaloids Source classification Cassytha filiformis L. Quinoline Alkaloids Plants Lauraceae	Others
1,2-Methylenedioxy-3,10,11-trimethoxynoraporphine is a natural product .

HY-N11799

Neochilenin 3-O-Methylquercetin 4′-O-glucoside	Structural Classification Flavonoids Source classification Plants Compositae Other Flavonoids	Others
Neochilenin (3-O-Methylquercetin 4 '-O-glucoside) is a glycoside of 3-O-methylquercetin, which can be isolated from the sub-family Cereoideae (Cactaceae). .

HY-N2802

Euptox A 9-Oxo-10,11-dehydroageraphorone	Structural Classification Terpenoids Sesquiterpenes Source classification Plants Compositae Derris indica	Apoptosis Caspase Parasite
Euptox A (9-Oxo-10, 11-dehydroageraphorone), a cadenine sesquiterpene, is the main toxin that can be isolated from Eupatorium adenophorum. Euptox A induces apoptosis by improving the gene expression level of apoptotic proteases such as caspase-10 in HeLa cells .

HY-W011474

Geranylgeraniol	Structural Classification Natural Products Microorganisms	NF-κB
Geranylgeraniol is an orally acitve vitamin K₂ sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model ^[2] .

HY-N12581

Kuwanon U	Structural Classification Flavonoids Flavonones Source classification Morus alba L. Plants Moraceae	Cholinesterase (ChE)
Kuwanon U is a potent cholinesterase inhibitor with IC₅₀s of 19.69, 10.11 µM and K_is of 6.48, 9.59 µM for acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), respectively. Kuwanon U has the potential for the research of Alzheimer’s disease (AD) .

HY-P2274

Argifin	Infection Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields	Parasite
Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms, with IC₅₀s of 0.025 μM, 6.4 μM , 1.1 μM and 4.5 μM for SmChiA (Serratia marcescens chitinaese A), SmChiB, Aspergillus fumigatus chitinase B1 and human chitotriosidase, respectively .

HY-N10192

Aculene D	Infection Microorganisms Classification of Application Fields Terpenoids Sesquiterpenes Source classification Disease Research Fields	Endogenous Metabolite Bacterial
Aculene D, a fungal metabolite, shows quorum sensing (QS) inhibitory activity against Chromobacterium violaceum CV026, and could significantly reduce violacein production in N-hexanoyl-l-homoserine lactone (C6-HSL) induced C. violaceum CV026 cultures at sub-inhibitory concentrations .

HY-W011474R

Geranylgeraniol (Standard)	Structural Classification Natural Products Microorganisms	NF-κB
Geranylgeraniol (Standard) is the analytical standard of Geranylgeraniol. This product is intended for research and analytical applications. Geranylgeraniol is an orally acitve vitamin K2 sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model ^[2] [4].

HY-N0662

Amentoflavone Maximum Cited Publications 9 Publications Verification Didemethyl-ginkgetin	Structural Classification Flavonoids Classification of Application Fields Source classification Phenols Polyphenols Selaginellaceae Plants Biflavones Selaginella tamariscina (P. Beauv.) Spring Disease Research Fields Cancer	Reactive Oxygen Species Apoptosis Bacterial Fungal RSV GABA Receptor
Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active GABA(A) negative modulator. Amentoflavone also shows anti-inflammatory, antioxidative, anti-viral, anti-tumor, anti-radiation, anti-fungal, antibacterial activity. Amentoflavone induces apoptosis and cell cycle arrest at sub-G1 phase ^[2] .

HY-N0662R

Amentoflavone (Standard)	Structural Classification Flavonoids Source classification Phenols Polyphenols Selaginellaceae Plants Biflavones Selaginella tamariscina (P. Beauv.) Spring	Reactive Oxygen Species Apoptosis Bacterial Fungal RSV GABA Receptor
Amentoflavone (Standard) is the analytical standard of Amentoflavone. This product is intended for research and analytical applications. Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active GABA(A) negative modulator. Amentoflavone also shows anti-inflammatory, antioxidative, anti-viral, anti-tumor, anti-radiation, anti-fungal, antibacterial activity. Amentoflavone induces apoptosis and cell cycle arrest at sub-G1 phase ^[2] .

HY-N8402

Germacrone 4,5-epoxide	Structural Classification Terpenoids Sesquiterpenes Source classification Plants Curcuma phaeocaulis Valeton Zingiberaceae	Others
Germacrone 4,5-epoxide is a sesquiterpene that can be isolated from Curcuma cf. viridiflora. Germacrone 4,5-epoxide has excellent anti-leukemic activities .

HY-B0504S

Creatinine-d3 3 Publications Verification NSC13123-d<sub>3sub>	Classification of Application Fields Metabolic Disease Disease Research Fields	Endogenous Metabolite
Creatinine-d₃ is a deuterium labeled Creatinine. Creatinine is a break-down product of creatine phosphate in muscle[1].

HY-N9233

Schisandrin C epoxide	Structural Classification Flourensia oolepis S.F.Blake Labiatae Source classification Lignans Phenylpropanoids Plants	Others
Schisandrin C epoxide (compound 1) is a natural lignan found in Clerodendron inerme seeds .

HY-130550

(±)7(8)-EpDPA	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Endogenous Metabolite
(±)7(8)-EpDPA is an epoxide derivative of docosahexaenoic acid (DHA) metabolized by CYP450 .

HY-D0186

2'-Deoxyuridine 1 Publications Verification	Infection Structural Classification Natural Products Immune System Disorder Microorganisms Classification of Application Fields Source classification Disease markers Endogenous metabolite Disease Research Fields	Endogenous Metabolite Thymidylate Synthase
2’-deoxyuridine is a brain-penetrant pyrimidines nucleotide that is associated with nervous system diseases. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. 2'-Deoxyuridine is a precursor in the synthesis of Edoxudine (HY-B1011) and also an analogue of 5-ethynyl-2'-deoxyuridine, EdU (HY-118411). 2’-deoxyuridine reduces microglial activation and improve oxidative stress damage by modulating glycolytic metabolism on the Aβ25-35-induced brain injury, which is promising for research of Alzheimer’s disease (AD) ^[2] .

HY-N1282

Seneciphylline	Alkaloids Structural Classification other families Pyrrole Alkaloids Classification of Application Fields Source classification Plants Compositae Sophora yunnanensis C. Y. Ma Disease Research Fields Cancer	Glutathione S-transferase Cytochrome P450
Seneciphylline is a toxic pyrrolizidine alkaloid in Gynura japonica . Seneciphylline significantly increases the activities of epoxide hydrase and glutathione-S-transferase but causes reduction of cytochrome P-450 and related monooxygenase activities ^[2].

HY-N10837

rel-3R-Methoxy-4S-furanogermacra-1E,10(15)-dien-6-one	Structural Classification Commiphora myrrha (Nees) Engl. Terpenoids Sesquiterpenes Source classification Plants Burseraceae	Others
rel-3-Methoxy-8,12-epoxygermacra-1,7,10,11-tetraen-6-one (compound 4) is a natural product that can be found in Commiphora erythraea .

HY-N6772

Cytochalasin E	Alkaloids Structural Classification Microorganisms Pyrrole Alkaloids Classification of Application Fields Source classification Disease Research Fields Cancer	Autophagy
Cytochalasin E, an epoxide containing Aspergillus-derived fungal metabolite, inhibits angiogenesis and tumor growth. Cytochalasin E is a potent actin depolymerization agent, and it binds and caps the barbed end of actin filaments to prevent actin elongation ^[2].

HY-A0210

Cerulenin 5+ Cited Publications	Structural Classification Microorganisms Antifungal Classification of Application Fields Antibiotics Source classification Metabolic Disease Mammalian Cell Culture Disease Research Anticancer Disease Research Fields Other Antibiotics	Fatty Acid Synthase (FASN) Fungal Apoptosis Antibiotic
Cerulenin, a potent, natural inhibitor of fatty acid synthase (FASN), is an epoxide produced by the fungus Cephalosporium caeruleus. Cerulenin inhibits topoisomerase I catalytic activity and augments SN-38-induced apoptosis. Cerulenin has antifungal and antitumor activies ^[2] .

HY-N9149

Cryptanoside A	Apocynaceae Triterpenes Structural Classification Terpenoids Source classification Plants Cryptolepis buchananii Roem. et Schult.	Na+/K+ ATPase Akt NF-κB
Cryptanoside A, a cardiac glycoside epoxide, can be isolated from the stems of Cryptolepis dubia. Cryptanoside A has potent cytotoxicity against cancer cells. Cryptanoside A also inhibits Na+/K+-ATPase activity. Cryptanoside A increases the expression of Akt and the p65 subunit of NF-κB .

HY-N12955

8(R),9(S)-EET	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Endogenous Metabolite
8(R),9(S)-EET is an isomer of Epoxyeicosatrienoic acid (HY-113489). 8(R),9(S)-EET processes its metabolism with cytosolic epoxide hydrolase (cEH), with a binding affinity of K_m of 41 μM .

HY-110013

Terreic acid	Microorganisms Source classification	Btk Antibiotic
Terreic acid, a quinone epoxide antibiotic, acts as an effective Btk inhibitor. Terreic acid blocks the interaction between PKC and the pleckstrin homology domain of Btk. Terreic acid inhibits the binding of GST-BtkPH to PKC in lysates of HMC-1 human mast cells with an IC₅₀ of approximately 100 μM .

HY-N1282R

Seneciphylline (Standard)	Alkaloids Structural Classification other families Pyrrole Alkaloids Source classification Plants Compositae Sophora yunnanensis C. Y. Ma	Glutathione S-transferase Cytochrome P450
Seneciphylline (Standard) is the analytical standard of Seneciphylline. This product is intended for research and analytical applications. Seneciphylline is a toxic pyrrolizidine alkaloid in Gynura japonica . Seneciphylline significantly increases the activities of epoxide hydrase and glutathione-S-transferase but causes reduction of cytochrome P-450 and related monooxygenase activities ^[2].

HY-N7008

Fructo-oligosaccharide DP11/GF10	Polysaccharides Classification of Application Fields Source classification Rubiaceae Metabolic Disease Plants Morinda officinalis How Disease Research Fields Saccharides	Others
Fructo-oligosaccharide DP11/GF10 belongs to fructooligosaccharides (FOS) with degree of polymerization (DP=11). Fructo-oligosaccharides (FOS) are composed of 10 fructose units linked by (2→1)-β-glycosidic bonds and having a single D-glucosyl unit at the non-reducing end .

HY-W024365

3-tert-Butyl-4-methoxyphenol	Structural Classification Monophenols Source classification Jatropha curcas Linn. Phenols Euphorbiaceae Plants	PROTAC Linkers
3-tert-Butyl-4-methoxyphenol is a PROTAC linker, belongs to alkyl/ether class, with insecticidal activity. 3-tert-Butyl-4-methoxyphenol also induced increased activities of glutathione (GSH) S-transferase and epoxide hydrolase in the liver and forestomach tissues of A/HeJ mice, regulating the carcinogen metabolism system ^[2].

HY-116620

Benzomalvin C	Human Gut Microbiota Metabolites Microorganisms Source classification Endogenous metabolite	Others
Benzomalvin C is a weak antagonist of the neurokinin-1 (NK1) receptor inhibiting binding of substance P by 46% when used at 100 μg/mL in vitro. It is also a weak inhibitor of indolamine 2,3-dioxygenase (IDO) with an IC₅₀ value of 130 μM for recombinant IDO. It is isolated from Penicillium and contains an epoxide group at C-19 and C-20, which is not present in benzomalvins A, B, or E.

HY-D0186R

2'-Deoxyuridine (Standard)	Structural Classification Natural Products Immune System Disorder Microorganisms Source classification Disease markers Endogenous metabolite	Endogenous Metabolite Thymidylate Synthase
2'-Deoxyuridine (Standard) is the analytical standard of 2'-Deoxyuridine. This product is intended for research and analytical applications. 2’-deoxyuridine is a brain-penetrant pyrimidines nucleotide that is associated with nervous system diseases. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. 2'-Deoxyuridine is a precursor in the synthesis of Edoxudine (HY-B1011) and also an analogue of 5-ethynyl-2'-deoxyuridine, EdU (HY-118411). 2’-deoxyuridine reduces microglial activation and improve oxidative stress damage by modulating glycolytic metabolism on the Aβ25-35-induced brain injury, which is promising for research of Alzheimer’s disease (AD) ^[2] . In Vitro:The interaction between the 2-deoxyuridine and the column increases the duration of retention of 2-deoxyuridine ^[2]. Gradient elution with sodium acetate buffer-ACN eluent on two ZIC-HILIC homemade columns separates 2-deoxyuridine in under 9 min ^[2]. In Vivo:2'-Deoxyuridine (34.42 ng/mL, gavage, 15 min) passes the blood-brain barrier (BBB) to enter the hippocampus of mice brain . 2'-Deoxyuridine (20 mg/kg, gavage, daily for 4 weeks) improves cognition and memory loss and attenuates the damage to the hippocampus in Aβ25-35-induced mice model .

HY-W024365R

3-tert-Butyl-4-methoxyphenol (Standard)	Structural Classification Monophenols Source classification Jatropha curcas Linn. Phenols Euphorbiaceae Plants	PROTAC Linkers
3-tert-Butyl-4-methoxyphenol (Standard) is the analytical standard of 3-tert-Butyl-4-methoxyphenol. This product is intended for research and analytical applications. 3-tert-Butyl-4-methoxyphenol is a PROTAC linker, belongs to alkyl/ether class, with insecticidal activity. 3-tert-Butyl-4-methoxyphenol also induced increased activities of glutathione (GSH) S-transferase and epoxide hydrolase in the liver and forestomach tissues of A/HeJ mice, regulating the carcinogen metabolism system ^[2].

HY-N2037

Higenamine 3 Publications Verification Norcoclaurine; Demethyl-Coclaurine	Alkaloids Structural Classification Classification of Application Fields Ranunculaceae Source classification Phenols Polyphenols Aconitum carmichaeli Debx. Plants Isoquinoline Alkaloids Disease Research Fields Endocrinology	MAP3K MDM-2/p53 Adrenergic Receptor ROS Kinase Apoptosis
Higenamine (Norcoclaurine), a *β2-AR* agonist with antioxidant capability, is a key component of the Chinese herb aconite root that prescribes for treating symptoms of heart failure in the oriental Asian countries. Higenamine is also a α1-adrenergic receptor antagonist with hypotensive effect. is a selective LSD1 inhibitor (IC₅₀=1.47 μM) that can be isolated from aconite. Higenamine hydrochloride has anti-inflammatory and antibacterial activity. Higenamine protects myocyte Apoptosis and ischemia/reperfusion (I/R) injury through selective activation of beta2-adrenergic receptor (β2-AR). Higenamine also reduces I/R-induced myocardial infarction in mice. Higenamine can attenuate IL-1β-induced Apoptosis through ROS-mediated PI3K/Akt signaling pathway. Higenamine protects brain cells from oxygen deprivation. Higenamine can promote bone formation in osteoporosis through the SMAD2/3 pathway. Higenamine can be used to study cancer, inflammation, cardiorenal syndrome and other diseases ^[2] ^[10] .

Cat. No.	Product Name	Chemical Structure

HY-W013378S1

Carbamazepine 10,11 epoxide-d10
Carbamazepine 10,11 epoxide-d₁₀ is the deuterium labeled Carbamazepine 10,11 epoxide[1].

HY-W013378S

Carbamazepine 10,11 epoxide-d2
Carbamazepine 10,11 epoxide-d₂ is the deuterium labeled Carbamazepine 10,11 epoxide[1]. Carbamazepine 10,11-epoxide is an orally active metabolite of Carbamazepine (HY-B0246). Carbamazepine has anticonvulsant effect. Carbamazepine can be used for the research of seizures[2].

HY-W013378S2

Carbamazepine 10,11-epoxide-13C,d2

Carbamazepine 10,11-epoxide- ¹³C,d₂ is the deuterium labeled Carbamazepine 10,11-epoxide-C13. Carbamazepine 10,11-epoxide-C13 is a ¹³C-labled Carbamazepine 10,11-epoxide. Carbamazepine 10,11-epoxide is an orally active metabolite of Carbamazepine (HY-B0246). Carbamazepine has anticonvulsant effect. Carbamazepine can be used for the research of seizures[1][2].

HY-W013378S4

Carbamazepine 10,11-epoxide-13C
Carbamazepine 10,11-epoxide- ¹³C is the ¹³C labeled Carbamazepine 10,11-epoxide (HY-W013378)[1].

HY-W013378S5

Carbamazepine 10,11-epoxide-13C-1
Carbamazepine 10,11-epoxide- ¹³C-1 is the ¹³C labeled Carbamazepine 10,11-epoxide (HY-W013378)[1].

HY-W013378S3

Carbamazepine 10,11-epoxide-13C-15N
Carbamazepine 10,11-epoxide- ¹³C, ¹⁵N is the ¹³C and ¹⁵N labeled Carbamazepine 10,11-epoxide (HY-W013378)[1].

HY-B0246S1

Carbamazepine-d2
Carbamazepine-d₂ is the deuterium labeled Carbamazepine. Carbamazepine, a sodium channel blocker, is an anticonvulsant agent.

HY-W653882

Carbamazepine-d2,15N
Carbamazepine-d2,15N is a deuterated labeled Carbamazepine-d2,15N .

HY-B0246S4

Carbamazepine-d4
Carbamazepine-d4 (CBZ-d4; NSC 169864-d4) is the deuterium labeled Carbamazepine-d4 (HY-B0246S4) .

HY-113164S

*Vitamin K1 2,3-epoxide-d7*
Vitamin K1 2,3-epoxide-d₇ is the deuterium labeled Vitamin K1 2,3-epoxide[1].

HY-133971S

*Cholesterol-5α,6α-epoxide-d7*
Cholesterol-5α,6α-epoxide-d₇ is deuterium labeled Cholesterol-5α,6α-epoxide.

HY-156756S

*7-Hydroxymethyl-10,11-MDCPT-d5*
7-Hydroxymethyl-10,11-MDCPT-d₅ is deuterium labeled 7-Hydroxymethyl-10,11-MDCPT, which is a is a payload that can be used for ADC synthesis .

HY-10844S1

Pretomanid-d5
Pretomanid-d₅ is deuterated labeled Pretomanid (HY-10844). Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 μg/mL.

HY-B0246S3

Carbamazepine-(Ph)d8
Carbamazepine-(Ph)d8 (CBZ-(Ph)d8; NSC 169864-(Ph)d8) is the deuterium labeled Carbamazepine-(Ph) (HY-B0246) .

HY-B0389S26

D-Glucose-d2-2
D-Glucose-d₂-2 is the deuterium labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling mol

HY-Y0418S4

Dulcite-d2
Dulcite-d₂ is the deuterium labeled Dulcite. Dulcite is a sugar alcohol with a slightly sweet taste which is a metabolic breakdown product of galact[1][2].

HY-B0400S9

D-Sorbitol-d2-2
D-Sorbitol-d₂-2 is the deuterium labeled D-Sorbitol. D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and di

HY-B0389S5

D-Glucose-d2
D-Glucose-d₂2 is the deuterium labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].

HY-B0141AS1

Alpha-Estradiol-d2
Alpha-Estradiol-d₂ is the deuterium labeled Alpha-Estradiol. Alpha-Estradiol is a weak estrogen and a 5α-reductase inhibitor which is used as a topical medication in the treatment of androgenic alopecia[1].

HY-B0389S22

D-Glucose-13C2,d2
D-Glucose- ¹³C₂,d₂ is the deuterium and ¹³C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical si

HY-107542S2

Oleoylethanolamide-d2
Oleoylethanolamide-d₂ is the deuterium labeled Oleoylethanolamide. Oleoylethanolamide is a high affinity endogenous PPAR-α agonist, which plays an important role in the treatment of obesity and arteriosclerosis.

HY-77839S1

Cortodoxone-d2
Cortodoxone-d₂ is the deuterium labeled Cortodoxone. Cortodoxone is a glucocorticoid steroid hormone that can be oxygenated to cortisol (Hydrocortisone)[1].

HY-B0511S2

Biotin-d2
Biotin-d₂ is the deuterium labeled Biotin. Biotin is an enzyme co-factor present in minute amounts in every living cell.

HY-101047S1

D-erythro-Sphingosine-13C2,d2
D-erythro-Sphingosine-13C2,d2 is a deuterated labeled D-erythro-Sphingosine . D-erythro-Sphingosine (Erythrosphingosine) is a very potent activator of p32-kinase with an EC₅₀ of 8 μM, and inhibits protein kinase C (PKC). D-erythro-Sphingosine (Erythrosphingosine) is also a *PP2A* activator ^[2] .

HY-13632S

Exemestane-d2
Exemestane-d₂ is the deuterium labeled Exemestane. Exemestane (FCE 24304) is a selective, irreversible and orally active steroidal aromatase inhibitor with IC50s of 30 nM and 40 nM for human placental and rat ovarian aromatase, respectively. Exemestane can be used for hormone-dependent breast cancer research[1][2].

HY-B0234S1

Estrone-d2
Estrone-d₂ is the deuterium labeled Estrone. Estrone (E1) is a natural estrogenic hormone. Estrone is the main representative of the endogenous estrogens and is produced by several tissues, especially adipose tissue. Estrone is the result of the process of aromatization of androstenedione that occurs in fat cells[1][2].

HY-N0378S4

D-Mannitol-d2
D-Mannitol-d₂ is the deuterium labeled D-Mannitol.

HY-N1150S6

Thymidine-d2
Thymidine-d₂ is the deuterium labeled Thymidine. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication[1

HY-B0141S3

Estradiol-d2
Estradiol-d₂ is the deuterium labeled Estradiol. Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway[1][2][3].

HY-B0389S4

D-Glucose-d1-2
D-Glucose-d1-2 is the deuterium labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].

HY-W338294S3

2'-Deoxycytidine-d2 monohydrate
2'-Deoxycytidine-d₂ (monohydrate) is the deuterium labeled (R)-2,3-Dihydroxypropanal[1].

HY-B0389S23

D-Glucose-d2-1
D-Glucose-d₂-1 is the deuterium labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling mol

HY-B0021S

Doxifluridine-d2
Doxifluridine-d₂ is the deuterium labeled Doxifluridine[1]. Doxifluridine is a thymidine phosphorylase activator for PC9-DPE2 cells with IC50 of 0.62 μM.

HY-13677S

6-Mercaptopurine-d2
6-Mercaptopurine-d₂ is the deuterium labeled 6-Mercaptopurine. 6-Mercaptopurine is a purine analogue which acts as an antagonist of the endogenous purines and has been widely used as antileukemic agent and immunosuppressive agent[1][2].

HY-13623S

Entecavir-d2
Entecavir-d₂ is the deuterium labeled Entecavir. Entecavir (SQ 34676; BMS 200475) is a potent and selective inhibitor of HBV, with an EC50 of 3.75 nM in HepG2 cell.

HY-N0650S7

L-Serine-d2
L-Serine-d₂ is the deuterium labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-W004282S2

Undecanoic acid-d2
Undecanoic acid-d₂ is the deuterium labeled Undecanoic acid. Undecanoic acid (Undecanoate) is a monocarboxylic acid with antimycotic property, which inhibits the production of exocellular keratinase, lipase and the biosynthesis of several phospholipids in T. rubrum[1].

HY-B0400S4

D-Sorbitol-d2
D-Sorbitol-d₂ is the deuterium labeled D-Sorbitol. D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and diet

HY-B0228S6

Adenosine-d2
Adenosine-d₂ is the deuterium labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physio

HY-B0141S6

Estradiol-d2-1
Estradiol-d₂-1 is the deuterium labeled Estradiol. Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway[1][2][3][4].

HY-W013812S2

Ethyl linoleate-d2
Ethyl linoleate-d₂ (Linoleic Acid ethyl ester-d₂; Mandenol-d₂) is the deuterium labeled Ethyl linoleate (HY-W013812). Ethyl linoleate (Linoleic Acid ethyl ester) inhibit the development of atherosclerotic lesions and the expression of inflammatory mediators ^[2].

HY-Y0069S1

N-Acetylglycine-d2
N-Acetylglycine-d₂ (Aceturic acid-d₂; Acetamidoacetic acid-d₂) is the deuterated labeled N-Acetylglycine (HY-Y0069). N-Acetylglycine (Aceturic acid) is a minor constituent of numerous foods with no genotoxicity or acute toxicity. N-acetylglycine is used in biological research of peptidomimetics .

HY-B0511S

Biotin-d2-1
Biotin-d₂-1 is the deuterium labeled Biotin. Biotin is an enzyme co-factor present in minute amounts in every living cell.

HY-Y0921S1

(±)-1,2-Propanediol-d2
(±)-1,2-Propanediol-d₂ is the deuterium labeled (±)-1,2-Propanediol. (±)-1,2-Propanediol (1,2-(RS)-Propanediol) is an aliphatic alcohol and frequently used as an excipient in many agent formulations to increase the solubility and stability of agents.

HY-16637S

Folic acid-d2
Folic acid-d₂ (Vitamin B9-d₂) is the deuterium labeled Folic acid. Folic acid (Vitamin M; Vitamin B9) is a B vitamin; is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis.

HY-N0682S1

Pyridoxine-d2 hydrochloride
Pyridoxine-d₂ (hydrochloride) is the deuterium labeled Pyridoxine hydrochloride. Pyridoxine hydrochloride is a pyridine derivative. Pyridoxine (Pyridoxol; Vitamin B6) exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway.

HY-B0234S4

Estrone-d2-1
Estrone-d₂-1 is the deuterium labeled Estrone. Estrone (E1) is a natural estrogenic hormone. Estrone is the main representative of the endogenous estrogens and is produced by several tissues, especially adipose tissue. Estrone is the result of the process of aromatization of androstenedione that occurs in fat cells[1][2].

HY-B1203S1

Fludrocortisone-d2
Fludrocortisone-d₂ is the deuterium labeled Fludrocortisone. Fludrocortisone, a synthetic mineralocorticoid with anti-inflammatory activity.

HY-B0166S6

L-Ascorbic acid-d2
L-Ascorbic acid-d₂ is the deuterium labeled L-Ascorbic acid. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a colla

HY-A0281S3

4-Phenylbutyric acid-d2
4-Phenylbutyric acid-d₂ is the deuterium labeled 4-Phenylbutyric acid[1]. 4-Phenylbutyric acid (4-PBA) is an inhibitor of HDAC and endoplasmic reticulum (ER) stress, used in cancer and infection research.

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