Search Result

Pathways Recommended:	Antibody-drug Conjugate/ADC Related

Results for "

Conjugated

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Peptide-Drug Conjugate (PDC) (10) 17β-HSD (1) ADC Antibody (25) ADC Cytotoxin (86) ADC Linker (729) Adrenergic Receptor (1) Akt (5) ALCAM/CD166 (1) Aldehyde Dehydrogenase (ALDH) (1) Amino Acid Derivatives (3) Aminopeptidase (2) Amyloid-β (2) Androgen Receptor (3) Angiotensin Receptor (2) ANGPTL (2) Antibiotic (17) Antibody-Drug Conjugates (ADCs) (55) Antifolate (4) Apolipoprotein (2) Apoptosis (157) AUTACs (5) Autophagy (180) AUTOTACs (4) Bacterial (31) Bcl-2 Family (1) BCL6 (2) Bcr-Abl (12) BCRP (1) Biochemical Assay Reagents (223) Btk (4) c-Met/HGFR (1) c-Myc (2) Calcium Channel (1) Cannabinoid Receptor (1) Casein Kinase (1) Caspase (1) CCR (1) CD19 (1) CD22 (3) CD276/B7-H3 (1) CDK (1) Checkpoint Kinase (Chk) (1) Cholinesterase (ChE) (1) CMV (1) Complement System (3) COX (1) CXCR (3) Cytochrome P450 (4) DNA Alkylator/Crosslinker (16) DNA Methyltransferase (1) DNA/RNA Synthesis (18) Dopamine Receptor (1) Drug Metabolite (9) Drug-Linker Conjugates for ADC (290) E-Selectin (1) E1/E2/E3 Enzyme (3) E3 Ligase Ligand-Linker Conjugates (562) EGFR (20) Elastase (1) Endogenous Metabolite (55) Epigenetic Reader Domain (14) Estrogen Receptor/ERR (7) Eukaryotic Initiation Factor (eIF) (1) FAAH (1) FAP (2) Fatty Acid Synthase (FASN) (1) Ferroptosis (3) FGFR (1) Fluorescent Dye (73) Folate Receptor (FR) (1) Fungal (1) GABA Receptor (1) GCGR (1) GHR (2) GLP Receptor (2) Glucocorticoid Receptor (13) GLUT (3) Glutathione Peroxidase (1) Glutathione S-transferase (2) HBV (2) HCV (2) HDAC (3) Herbicide (1) HIF/HIF Prolyl-Hydroxylase (3) Histamine Receptor (2) Histone Acetyltransferase (2) Histone Demethylase (1) HIV (5) HSP (4) HSV (1) IGF-1R (1) Influenza Virus (2) Integrin (8) Interleukin Related (6) Isotope-Labeled Compounds (7) Keap1-Nrf2 (1) Kinesin (1) Lactate Dehydrogenase (1) Ligands for E3 Ligase (70) Ligands for Target Protein for PROTAC (4) Liposome (50) LXR (1) MARCKS (1) MDM-2/p53 (2) Melatonin Receptor (1) Mesothelin (1) MicroRNA (2) Microtubule/Tubulin (59) Mitochondrial Metabolism (4) Mitophagy (2) Mixed Lineage Kinase (2) MMP (1) Monoamine Oxidase (2) mTOR (1) Na+/K+ ATPase (1) NAMPT (4) Nectin-4 (3) Neurokinin Receptor (1) NF-κB (1) Notch (1) Nucleoside Antimetabolite/Analog (3) Opioid Receptor (1) Orthopoxvirus (2) P2Y Receptor (1) p38 MAPK (1) p62 (1) Parasite (2) PARP (2) PD-1/PD-L1 (7) PERK (1) Photosensitizer (1) PI3K (2) PKC (7) Polo-like Kinase (PLK) (1) Potassium Channel (2) PPAR (1) Prostaglandin Receptor (1) PROTAC Linkers (209) PROTAC-Linker Conjugates for PAC (5) PROTACs (45) Proteasome (1) Proton Pump (1) PSMA (4) Radionuclide-Drug Conjugates (RDCs) (39) RAR/RXR (1) Reactive Oxygen Species (4) SARS-CoV (1) Ser/Thr Protease (2) Small Interfering RNA (siRNA) (9) SNIPERs (13) Sodium Channel (1) Somatostatin Receptor (2) STAT (2) Stearoyl-CoA Desaturase (SCD) (1) STING (9) TAM Receptor (3) Target Protein Ligand-Linker Conjugates (15) Tau Protein (1) Thrombin (1) Thyroid Hormone Receptor (1) TNF Receptor (10) Toll-like Receptor (TLR) (8) Topoisomerase (59) Transthyretin (TTR) (2) TROP2 (5) TRP Channel (2) WDR5 (1) YAP (1) β-catenin (1)
By Research Areas:	Cancer (2063) Cardiovascular Disease (13) Endocrinology (4) Infection (37) Inflammation/Immunology (206) Metabolic Disease (51) Neurological Disease (30)
Click Chemistry:	ADC Synthesis (233) Labeling and Fluorescence Imaging (4) TCO (15) DBCO (67) PROTAC Synthesis (56) Azide (124) BCN (22) Tetrazine (33) Alkynes (64)
Oligonucleotides:	Fluorescent Lipids (8) Nucleotides and their Analogs (2) Pegylated Lipids (43) Liposomal Film-forming Agents (1) Aptamers (1) Emulsifiers (1) Phospholipids (3) Cationic Lipids (1) Polymers (16) Antisense Oligonucleotides (10) Cholesterol (5) siRNAs (9)

2672

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

312

Biochemical Assay Reagents

Peptides

MCE Kits

Inhibitory Antibodies

Natural
Products

Isotope-Labeled Compounds

Antibodies

318

Click Chemistry

Oligonucleotides

Targets Recommended: Peptide-Drug Conjugate (PDC)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-148495

*Carnosine conjugated* hyalyronate**	Amyloid-β	Neurological Disease
Carnosine conjugated hyalyronate is a hyaluronic acid derivative functionalized with the dipeptide carnosine (Carnosine, Car) and has the ability to resist Aβ amyloid aggregation. Carnosine conjugated hyalyronate dissolves amyloid fibrils and reduces Aβ-induced toxicity in vitro. The effectiveness of Carnosine conjugated hyalyronate against amyloid aggregation is directly proportional to the Carnosine loading .

HY-124370

*9(Z),11(E)-Conjugated* linoleic acid methyl ester** 9Z,11E-CLA; Methyl 9(Z),11(E)-octadecadienoate; (9Z,11E)-SFE 19:2	Endogenous Metabolite	Cardiovascular Disease Inflammation/Immunology Cancer
9(Z),11(E)-Conjugated linoleic acid methyl ester (9Z,11E-CLA; Methyl 9(Z),11(E)-octadecadienoate; (9Z,11E)-SFE 19:2) is an isomer of Linoleic acid (HY-N0729). Conjugated linoleic acid is a bioactive fatty acid, which can improve body composition, enhance immune system function, exhibits anti-cancer and antiatherosclerosis effect .

HY-115691

STY-BODIPY Styrene-BODIPY; Styrene-Conjugated BODIPY	Fluorescent Dye	Others
STY-BODIPY (Styrene-BODIPY) is a styrene-conjugated fluorogenic probe for measuring radical-trapping antioxidant (RTA) activity .

HY-107906

Conjugated estrogen sodium	Estrogen Receptor/ERR	Endocrinology
Conjugated estrogen sodium is a medication composed of a blend of estrogen hormones, utilized in the treatment of moderate to severe hot flashes, vaginal changes, and various other symptoms associated with menopause or decreased estrogen levels.

HY-P10104

Smac-N7, Penetratin conjugated	Caspase	Cancer
Smac-N7, Penetratin conjugated is a caspase activator derived from the second mitochondria-derived activator of caspases (SMAC) .

HY-P10444

*DOTA Conjugated* JM#21 derivative 7**	Radionuclide-Drug Conjugates (RDCs) CXCR	Cancer
DOTA Conjugated JM#21 derivative 7 (compound Ligand-7) is a derivative of CXCR4 targeting peptide conjugated with DOTA and can be used to produce radioligands. Radiolabeled DOTA Conjugated JM#21 derivative 7, i.e., 177Lu-DOTA, has excellent CXCR4 tumor targeting. In vitro biodistribution results of 177Lu-DOTA showed very low uptake in all non-targeted organs except kidney .

HY-W923357

*9(Z),11(Z)-Conjugated* linoleic acid methyl ester** 9Z,11Z-CLA	Others	Metabolic Disease
9(Z),11(Z)-Conjugated linoleic acid methyl ester is a fatty acid derivative and a form of conjugated linoleic acid methyl ester .

HY-153195

Tetra-O-acetyl-β-D-galactopyranosyl-Ph-CH2OH-Fmoc	Others	Cancer
Tetra-O-acetyl-β-D-galactopyranosyl-Ph-CH2OH-Fmoc can be used as conjugates to prepare antibody drug conjugates (ADCs) .

HY-126493A

(R)-DM4-SPDP	Drug-Linker Conjugates for ADC	Others
(R)-DM4-SPDP is a conjugate made up of the linker SPDP and the toxic molecule DM4, and it can be used to prepare antibody-drug conjugates .

HY-P5439

Epsilon-V1-2, Cys-conjugated	PKC MARCKS	Others
Epsilon-V1-2, Cys-conjugated is a biological active peptide. (This peptide is the εPKC specific inhibitor. Its inhibitory activity is based on εPKC translocation and MARCKS phosphorylation. This peptide interferes with εPKC interaction with the anchoring protein εRACK. This peptide contains a cysteine residue added to the C-terminus for potential S-S bond formation with a carrier protein.Pyroglutamyl (pGlu) peptides may spontaneously form when either Glutamine (Q) or Glutamic acid (E) is located at the sequence N-terminus. The conversion of Q or E to pGlu is a natural occurrence and in general it is believed that the hydrophobic γ-lactam ring of pGlu may play a role in peptide stability against gastrointestinal proteases. Pyroglutamyl peptides are therefore considered a normal subset of such peptides and are included as part of the peptide purity during HPLC analysis.)

HY-D2261

*BODIPY-cholesterol conjugate-1*	Fluorescent Dye	Metabolic Disease
BODIPY-cholesterol conjugate-1 (compound 5) is a BODIPY-cholesterol conjugate. BODIPY-cholesterol conjugate-1 is a useful probe for simultaneous visualization of intracellular cholesterol pools and for monitoring cholesterol efflux from cells to extracellular acceptors . (λex 541 nm, λem 615 nm).

HY-D2262

*BODIPY-cholesterol conjugate-2*	Fluorescent Dye	Metabolic Disease
BODIPY-cholesterol conjugate-2 (compound 6) is a BODIPY-cholesterol conjugate. BODIPY-cholesterol conjugate-2 is a useful probe for simultaneous visualization of intracellular cholesterol pools and for monitoring cholesterol efflux from cells to extracellular acceptors. (λex=589 nm, λem=638 nm) .

HY-168659

*E3 Ligase Ligand-linker Conjugate* 130**	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 Ligase Ligand-linker Conjugate 130 is an E3 ligase ligand-linker conjugate. E3 Ligase Ligand-linker Conjugate 130 can be used to synthesize YJ1206 (HY-16855) .

HY-139957

Mal-amido-PEG8-Val-Ala-PAB-SG3200	Drug-Linker Conjugates for ADC	Others
Mal-amido-PEG8-Val-Ala-PAB-SG3200 is a *conjugate* for antibody-drug conjugate (ADC) (extracted from patent WO2016166300A1) .

HY-167016

Cholesterol-undecanoate-glucose conjugate	Liposome	Others
Cholesterol-undecanoate-glucose conjugate is a cholesterol conjugate used in the synthesis of intranasal liposomal vaccines. Cholesterol-undecanoate-glucose conjugate can be used in drug delivery studies .

HY-150074

STING agonist-18	Others	Cancer
STING agonist-18 (compound 1a) can be used for synthesis of antibody-drug conjugates (ADCs), such Trastuzumab (HY-P9907) conjugate .

HY-168256

*E3 Ligase Ligand-linker Conjugate* 128**	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 Ligase Ligand-linker Conjugate 128 (Intermediate 11) is an E3 ligase ligand-linker conjugate. E3 Ligase Ligand-linker Conjugate 128 can be used to synthesize PROTAC BRM/BRG1 degrader-4 (HY-168255) .

HY-150074A

STING agonist-18 diTFA	Others	Cancer
STING agonist-18 diTFA (compound 1a) can be used for synthesis of antibody-drug conjugates (ADCs), such Trastuzumab (HY-P9907) conjugate .

HY-168701

*E3 Ligase Ligand-linker Conjugate* 149**	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 Ligase Ligand-linker Conjugate 149 is an E3 ligase ligand-linker conjugate. E3 Ligase Ligand-linker Conjugate 149 can be used to synthesize Setidegrasib (HY-148273) .

HY-169995

*E3 Ligase Ligand-linker Conjugate* 143**	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 Ligase Ligand-linker Conjugate 143 is a conjugate of E3 ubiquitin ligase ligand + Linker, used for the synthesis of ACBI3 (HY-157228) .

HY-169990

*E3 Ligase Ligand-linker Conjugate* 142**	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 Ligase Ligand-linker Conjugate 142 is a conjugate of E3 ubiquitin ligase ligand + Linker, used for the synthesis of CFT8634 (HY-145925B) .

HY-168284

*E3 Ligase Ligand-linker Conjugate* 129**	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 Ligase Ligand-linker Conjugate 129 is an E3 ligase ligand-linker conjugate. E3 Ligase Ligand-linker Conjugate 129 can be used to synthesize DD205-291 (HY-168282) .

HY-170305

*E3 Ligase Ligand-linker Conjugate* 145**	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 Ligase Ligand-linker Conjugate 145 is a conjugate of E3 ubiquitin ligase ligand + Linker, used for the synthesis of PROTAC AR Degrader-7 (HY-160221) .

HY-169979

*E3 Ligase Ligand-linker Conjugate* 141**	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 Ligase Ligand-linker Conjugate 141 is a conjugate of E3 ubiquitin ligase ligand + Linker, used for the synthesis of PROTAC ER Degrader-12 (HY-160264) .

HY-116768

*10(E),12(Z)-Conjugated* linoleic acid methyl ester** 10E,12Z-CLA Methyl ester; Methyl 10(E),12(Z)-octadecadienoate methyl ester; (10E,12Z)-SFE 19:2	Biochemical Assay Reagents	Others
10(E),12(Z)-Conjugated linoleic acid methyl ester (10E,12Z-CLA Methyl ester; Methyl 10(E),12(Z)-octadecadienoate methyl ester; SFE 19:2) is derivative of conjugated linoleic acid. 10(E),12(Z)-Conjugated linoleic acid methyl ester is utilized in the quantification of 10(E),12(Z)-conjugated linoleic acid .

HY-147118

NHS-SS-Ph	ADC Linker	Cancer
NHS-SS-Ph is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-P4198

Fmoc-N(Me)-Sar10 Fmoc-Sar10	Biochemical Assay Reagents	Others
Fmoc-N(Me)-Sar10 can be used for synthesis of peptide ligand-agent conjugates .

HY-13631O

(1R)-Deruxtecan	Drug-Linker Conjugates for ADC	Cancer
(1R)-Deruxtecan is a drug-linker conjugates for ADC .

HY-160578

Glucosamine Cholesterol N-Cholesteryl succinyl glucosamine	Liposome	Others
Glucosamine Cholesterol (N-Cholesteryl succinyl glucosamine) is a glucosamine-based lipid conjugate, and can be used in the formation of lipid nanoparticles (LNPs) .

HY-160703

DMBA-SIL-PNP	Others	Cancer
DMBA-SIL-PNP (Compound 5) is an intermediate used for preparing Drug-Linker Conjugates, which can be applied in cancer research .

HY-139909

CL2E-SN38	Drug-Linker Conjugates for ADC	Cancer
CL2E-SN-38, a highly releasable and structurally stable antibody-SN-38-conjugate, is a part of the antibody drug conjugate (ADC). SN-38, the active metabolite of Irinotecan from camptothecins, is an Topoisomerase I inhibitor .

HY-139909A

CL2E-SN38 TFA	Drug-Linker Conjugates for ADC	Cancer
CL2E-SN-38 TFA, a highly releasable and structurally stable antibody-SN-38-conjugate, is a part of the antibody drug conjugate (ADC). SN-38, the active metabolite of Irinotecan from camptothecins, is an Topoisomerase I inhibitor .

HY-168295

*p62-ZZ Ligand-Linker Conjugate* 1**	E3 Ligase Ligand-Linker Conjugates Autophagy	Cancer
p62-ZZ Ligand-Linker Conjugate 1 is a p62-ZZ domain ligand-linker conjugate. p62-ZZ Ligand-Linker Conjugate 1 can be used to synthesize AUTOTAC VinclozolinM2-2204 (HY-161741) .

HY-138300

ALC-0159 5+ Cited Publications	Liposome	Inflammation/Immunology
ALC-0159, a polyethylene glycol (PEG) lipid conjugate, could be used as vaccine excipient .

HY-150075

STING agonist-19	Others	Others
STING agonist-19 can be used to synthesize ISAC (immune-stimulating antibody conjugates) molecule.

HY-168612

*E3 Ligase Ligand-linker Conjugate* 125**	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 Ligase Ligand-linker Conjugate 125 is an E3 ligase ligand-linker conjugate. E3 Ligase Ligand-linker Conjugate 125 can be used to synthesize PROTAC IRAK4 degrader-12 (HY-168586) .

HY-23641

NH-bis(C1-Boc)	ADC Linker	Cancer
NH-bis(C1-Boc)is a uncleavable linker used for antibody-drug conjugates (ADC).

HY-79129

Fmoc-D-Trp(Boc)-OH	ADC Linker	Cancer
Fmoc-D-Trp(Boc)-OH is a cleavable ADC linker that used in the synthesis of antibody-drug conjugates (ADCs).

HY-W097109A

Fmoc-(D-Phe)-OSu	ADC Linker	Cancer
Fmoc-(D-Phe)-Osu is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-138300A

ALC-0159 (Excipient)	Liposome	Inflammation/Immunology
ALC-0159 Excipient, a polyethylene glycol (PEG) lipid conjugate, could be used as vaccine excipient .

HY-168254

*E3 Ligase Ligand-linker Conjugate* 127**	E3 Ligase Ligand-Linker Conjugates	Cancer
E3 Ligase Ligand-linker Conjugate 127 is an E3 ligase ligand-linker conjugate. E3 Ligase Ligand-linker Conjugate 127 can be used to synthesize PROTAC BRM/BRG1 degrader-3 (HY-168251) .

HY-P99101

Vobramitamab AEX-4089	ADC Antibody	Cancer
Vobramitamab is a humanized B7-H3 monoclonal antibody (mAb). Vobramitamab conjugated with prodrug seco-DUBA (HY-132180A) via a cleavable linker, to form antibody-drug conjugate (ADC), the MGC018. .

HY-130961

Boc-Val-Dil-Dap-OH	ADC Linker	Cancer
Boc-Val-Dil-Dap-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-156727

Val-Cit-PABC-Ahx-May	ADC Linker	Cancer
Val-Cit-PABC-Ahx-May is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-136261

DM1-PEG4-DBCO	Drug-Linker Conjugates for ADC	Cancer
DM1-(PEG)4-DBCO is a agent-linker conjugate composed of a potent microtubulin inhibitor DM1 and a linker DBCO-PEG4-Ahx to make antibody agent conjugate (ADC). Mertansine (DM1) is a microtubulin inhibitor and is an antibody-conjugatable maytansinoid that is developed to overcome systemic toxicity associated with maytansine and to enhance tumor-specific delivery. DM1-PEG4-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-49382

Fluocinolone acetonide 3-benzylaniline	Target Protein Ligand-Linker Conjugates	Others
Fluocinolone acetonide 3-benzylaniline (Precursor Example 1) is a glucocorticoid receptor agonist-linker conjugate, which can be used for the synthesis of anti-CD40 antibody-drug conjugates (ADCs) .

HY-160257

DOPE-PEG-BDP FL,MW 5000	Biochemical Assay Reagents Liposome Fluorescent Dye	Others
DOPE-PEG-BDP FL,MW 5000 is a PEG-lipid-dye conjugate consists of a DOPE phospholipid which is an unsaturated phospholipid, a BDP FL fluorophore with featuring excitation and emission maxima at 504 and 514 nm respectively and a large PEG spacer which links the former substance together.

HY-W040236

m-PEG8-Amine	ADC Linker PROTAC Linkers	Cancer
m-PEG8-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-130976

N-Boc-Val-Dil-Dap-Doe	ADC Linker	Cancer
N-Boc-Val-Dil-Dap-Doe is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-130975

Boc-Val-Dil-Dap-Phe-OMe	ADC Linker	Cancer
Boc-Val-Dil-Dap-Phe-OMe is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W007324

Maleimide	Alkaloids Microorganisms Pyrrole Alkaloids Other Alkaloids Source classification Endogenous metabolite Disease Research Fields Cancer	ADC Linker
Maleimide can be used for production of antibody-drug conjugate (ADC) which is used in cancer research. Maleimide also be leveraged for the preparation of fluorogenic probe, which is mainly used for the specific detection of thiol analytes .

HY-113162

Bovinic acid 1 Publications Verification	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Bovinic acid is a conjugated linoleic acid with anticarcinogenic and anti-atherogenic activities.

HY-113293A

Estrone sulfate potassium 1 Publications Verification	Structural Classification Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Steroids Cancer	Endogenous Metabolite
Estrone sulfate potassium is a natural endogenous steroid and is an estrogen ester and conjugate .

HY-N1424

Glycoursodeoxycholic acid Ursodeoxycholylglycine	Structural Classification Microorganisms Source classification Endogenous metabolite Steroids	Endogenous Metabolite
Glycoursodeoxycholic acid, a acyl glycine and a bile acid-glycine conjugate, is a metabolite of ursodeoxycholic acid.

HY-122141

Glycohyocholic acid GHCA	Structural Classification Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite
Glycohyocholic acid(GHCA) is a glycine-conjugated form of the primary bile acid hyocholic acid .

HY-113427

trans-Vaccenic acid 1 Publications Verification	Structural Classification Animals Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
trans-Vaccenic acid is a precursor for the synthesis of saturated fatty acid in the rumen and of conjugated linoleic acid (CLA) at the tissue level.

HY-124422

Pentacosanoic acid	other families Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Plants Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Pentacosanoic acid is a 25-carbon long-chain saturated fatty acid. Pentacosanoic is a conjugate acid of a pentacosanoate .

HY-N1108

Uvedalin	Structural Classification Terpenoids Smallanthus uvedalia (Linnaeus) Mackenzie Source classification Diterpenoids Plants Compositae	Others
Uvedalin is a conjugated γ-lactone and oxygenated germacranolide that can be isolated from Polymnia uvedalia (L.) .

HY-141793

ATRA-biotin Biotin-ATRA-conjugate	Structural Classification Alkaloids Classification of Application Fields Other Alkaloids Source classification Endogenous metabolite Disease Research Fields Cancer	RAR/RXR PPAR Endogenous Metabolite Autophagy
ATRA-biotin (Biotin-ATRA-conjugate) is a biotin-conjugated ATRA. ATRA-biotin can be used to track ATRA in cells or a given tissue .

HY-N8252

Xanthoquinodin A1	Infection Quinones Microorganisms Classification of Application Fields Source classification Naphthalene Quinones Disease Research Fields	Antibiotic
Xanthoquinodin A1 is an anticoccidial antibiotic having a new xanthone-anthraquinone conjugate system .

HY-W020215

Tricarballylic acid	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Mitochondrial Metabolism Endogenous Metabolite
Tricarballylic acid, a conjugate acid of a tricarballylate, is a competitive inhibitor of the enzyme aconitate hydratase (aconitase; EC 4.2.1.3) with a K_i value of 0.52 mM .

HY-N1424R

Glycoursodeoxycholic acid (Standard)	Structural Classification Microorganisms Source classification Endogenous metabolite Steroids	Endogenous Metabolite
Glycoursodeoxycholic acid (Standard) is the analytical standard of Glycoursodeoxycholic acid. This product is intended for research and analytical applications. Glycoursodeoxycholic acid, a acyl glycine and a bile acid-glycine conjugate, is a metabolite of ursodeoxycholic acid.

HY-N0324

Cholic acid Maximum Cited Publications 8 Publications Verification	Structural Classification Human Gut Microbiota Metabolites Microorganisms Other disease Classification of Application Fields Source classification Disease markers Metabolic Disease Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite
Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. Cholic acid is orally active .

HY-N0324A

Cholic acid sodium Maximum Cited Publications 8 Publications Verification Sodium cholate	Structural Classification Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite
Cholic acid sodium is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. Cholic acid sodium is orally active .

HY-W034595

Eicosanedioic acid	Microorganisms Source classification	ADC Linker PROTAC Linkers
Eicosanedioic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Eicosanedioic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis

HY-117371

Hemiasterlin (-)-Hemiasterlin; Milnamide B	Alkaloids Structural Classification Classification of Application Fields Animals Marine natural products Sponge Disease Research Fields Indole Alkaloids Cancer	ADC Cytotoxin
Hemiasterlin ((-)-Hemiasterlin) is an antimitotic marine natural product with potent anticancer effcts. Hemiasterlin can be used as a cytotoxic payload (ADC Cytotoxin) in antibody-drug conjugates (ADCs) .

HY-N0324B

Cholic acid sodium hydrate	Source classification Endogenous metabolite Steroids	Endogenous Metabolite
Cholic acid sodium hydrate is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. Cholic acid sodium hydrate facilitates fat absorption and cholesterol excretion. Cholic acid sodium hydrate is orally active .

HY-77641

Cinnamoylglycine	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Cinnamoylglycine is a glycine conjugate of cinnamic acid and a urinary metabolite in human. Cinnamoylglycine is used as a potential urinary biomarker indicating intact or disrupted colonization resistance during and after antibiotic treatment .

HY-W041895

DL-Glutamic acid	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
DL-Glutamic acid is the conjugate acid of Glutamic acid, which acts as a fundamental metabolite. Comparing with the second phase of polymorphs α and β L-Glutamic acid, DL-Glutamic acid presents better stability .

HY-W034918

Docosanedioic acid	Structural Classification other families Classification of Application Fields Ketones, Aldehydes, Acids Source classification Plants Disease Research Fields Cancer	ADC Linker PROTAC Linkers
Docosanedioic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Docosanedioic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

HY-N1420A

Rhamnose monohydrate L-Rhamnose monohydrate	Structural Classification Microorganisms other families Classification of Application Fields Source classification Plants Disease Research Fields Saccharides Monosaccharides Cancer	Endogenous Metabolite
Rhamnose monohydrate (L-Rhamnose monohydrate) is a monosaccharide found in plants and bacteria. Rhamnose monohydrate-conjugated immunogens is used in immunotherapies . Rhamnose monohydrate crosses the epithelia via the transcellular pathway and acts as a marker of intestinal absorption .

HY-N6740

Beta-Zearalanol	Structural Classification Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Phenols Polyphenols Metabolic Disease Antibacterial Disease Research Disease Research Fields	Apoptosis
Beta-Zearalenol is an mycotoxin produced by Fusarium spp, which causes apoptosis and oxidative stress in mammalian reproductive cells . Beta-Zearalenol is the derivative of zearalenone (ZEA) which can conjugate with glucuronic acid .

HY-116374

Glycolithocholic acid Lithocholylglycine	Structural Classification Human Gut Microbiota Metabolites Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields Steroids	Endogenous Metabolite
Glycolithocholic acid (Lithocholylglycine), an endogenous metabolite, is a glycine-conjugated secondary bile acid. Glycolithocholic acid can be used to diagnose ulcerative colitis (UC), non-alcoholic steatohepatitis (NASH) and primary sclerosing cholangitis (PSC) .

HY-Y1055

Guanine 3 Publications Verification	Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Cancer	DNA/RNA Synthesis Endogenous Metabolite
Guanine is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds. Guanine has the potential to serve as a large-capacity N pool .

HY-121271

Kadsurin	Classification of Application Fields Source classification Lignans Phenylpropanoids Plants Schisandraceae Disease Research Fields Inflammation/Immunology Schisandra chinensis (Turcz.) Baill.	Others
Kadsurin, a natural compound from the stems of Kadsura heteroclita (Schizandraceae), results in significant decreases of CCL₄- induced lipid-peroxidation products, such as thiobarbituric acid reactive substances (TBA-RS), conjugated dienes and fluorescent products in the liver of mice .

HY-N7550

Latrunculin M	Structural Classification Natural Products Marine natural products Source classification Sponge	Fluorescent Dye
Latrunculin M is a highly selective actin-macrolide conjugate that can be isolated from marine products. Latrunculin M can be converted from Latrunculin B, which can effectively induce actin depolymerization and is a good probe for detecting the actin skeleton.

HY-N0324R

Cholic acid (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Other disease Classification of Application Fields Source classification Disease markers Metabolic Disease Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite
Cholic acid (Standard) is the analytical standard of Cholic acid. This product is intended for research and analytical applications. Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. Cholic acid is orally active .

HY-112942A

CMP-Sialic acid sodium salt 1 Publications Verification CMP-Neu5Ac sodium salt	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
CMP-Sialic acid (CMP-Neu5Ac) sodium salt is an allosteric inhibitor of UDP-GlcNAc 2-epimerase. CMP-Sialic acid sodium salt provides a substrate for Golgi sialyltransferases. CMP-Sialic acid sodium salt is an important sugar nucleotide for biosynthesis of sialic acid and its conjugates .

HY-112942

CMP-Sialic acid CMP-Neu5Ac	Structural Classification Natural Products Human Gut Microbiota Metabolites Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
CMP-Sialic acid (CMP-Neu5Ac) is an allosteric inhibitor of UDP-GlcNAc 2-epimerase. CMP-Sialic acid provides a substrate for Golgi sialyltransferases. CMP-Sialic acid is an important sugar nucleotide for biosynthesis of sialic acid and its conjugates .

HY-113095

γ-CEHC	Structural Classification Monophenols Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Phenols Endogenous metabolite Disease Research Fields	Drug Metabolite Endogenous Metabolite
γ-CEHC is a γ-tocopherol (HY-N7148) metabolite. γ-CEHC is mainly excreted into the urine rather than into the bile. γ-CEHC is present in conjugated form in human urine, mainly as glucuronide .

HY-134544

Calendic acid	Structural Classification Ketones, Aldehydes, Acids Source classification Plants Compositae Millettia usaramensis Taub.	Others
Calendic acid (8(E),10(E),12(Z)-Octadecatrienoic acid) is a conjugated polyunsaturated fatty acid (PUFA) that can be isolated from C. officinalis seed oil. Calendic acid has anticancer activity .

HY-N7497

Protoescigenin	Triterpenes Structural Classification other families Classification of Application Fields Terpenoids Source classification Other Diseases Plants Disease Research Fields	Others
Protoescigenin is the main aglycone of horse chestnut saponin mixture known as escin. Protoescigenin is selected as substrate for exploratory chemistry towards selective protection, followed by propargyl ether formation and subsequent condensation with azido-monosaccharides, to obtain novel triazole linked conjugates of the triterpene .

HY-W751418

N-Nervonoyl taurine (Z)-2-tetracos-15-enamidoethanesulfonic acid	Structural Classification Natural Products Source classification Endogenous metabolite	FAAH
N-Nervonoyl taurine ((Z)-2-tetracos-15-enamidoethanesulfonic acid) is a fatty acid-taurine conjugate derived from nervonic acid. N-Nervonoyl taurine is a substrate of fatty acid amide hydrolase (FAAH) discovered during metabolite profiling .

HY-77641R

Cinnamoylglycine (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Endogenous Metabolite
Cinnamoylglycine (Standard) is the analytical standard of Cinnamoylglycine. This product is intended for research and analytical applications. Cinnamoylglycine is a glycine conjugate of cinnamic acid and a urinary metabolite in human. Cinnamoylglycine is used as a potential urinary biomarker indicating intact or disrupted colonization resistance during and after antibiotic treatment .

HY-W041895R

DL-Glutamic acid (Standard)	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Endogenous Metabolite
DL-Glutamic acid (Standard) is the analytical standard of DL-Glutamic acid. This product is intended for research and analytical applications. DL-Glutamic acid is the conjugate acid of Glutamic acid, which acts as a fundamental metabolite. Comparing with the second phase of polymorphs α and β L-Glutamic acid, DL-Glutamic acid presents better stability .

HY-125934

Allocholic acid	Structural Classification Microorganisms Classification of Application Fields Animals Source classification Disease Research Fields Steroids Cancer	Others
Allocholic acid is a typically fetal bile acid found in vertebrates and reappears during liver regeneration and carcinogenesis, besides it is also a conjugate acid of allocholate and an isomer of cholic acid. Allocholic acid is a potent and specific stimulant of the adult olfactory system, it has a role as a marine metabolite, a rat metabolite and a human metabolite .

HY-150524

UDP-Galactose	Structural Classification Natural Products Human Gut Microbiota Metabolites Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite P2Y Receptor
UDP-Galactose is a monosaccharide involved in nucleotide sugar metabolism. UDP-Galactose and its derivatives act as a natural agonist for G_i protein-conjugated P2Y₁₄ receptors in the immune system (IC₅₀=0.67 μM, hP2Y₁₄) .

HY-N1420AR

Rhamnose monohydrate (Standard)	Structural Classification Microorganisms other families Source classification Plants Saccharides Monosaccharides	Endogenous Metabolite
Rhamnose (monohydrate) (Standard) is the analytical standard of Rhamnose (monohydrate). This product is intended for research and analytical applications. Rhamnose monohydrate (L-Rhamnose monohydrate) is a monosaccharide found in plants and bacteria. Rhamnose monohydrate-conjugated immunogens is used in immunotherapies . Rhamnose monohydrate crosses the epithelia via the transcellular pathway and acts as a marker of intestinal absorption .

HY-113003

H-γ-Glu-Gln-OH γ-Glutamylglutamine; γ-Glu-Gln	Structural Classification Animals Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Others
H-γ-Glu-Gln-OH is a hydrophilic peptide and can be conjugated to drugs. The carrier composed of H-γ-Glu-Gln-OH has the characteristics of high water solubility and drug-loading capacity, good biocompatibility, low toxicity, improved tumor targeting ability, and anti-tumor efficacy .

HY-Y1055R

Guanine (Standard)	Structural Classification Natural Products Microorganisms Source classification Endogenous metabolite	DNA/RNA Synthesis Endogenous Metabolite
Guanine (Standard) is the analytical standard of Guanine. This product is intended for research and analytical applications. Guanine is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds. Guanine has the potential to serve as a large-capacity N pool .

HY-101884

Biocytin 2 Publications Verification (+)-Biocytin	Structural Classification Human Gut Microbiota Metabolites Microorganisms Neurological Disease Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Biocytin is a conjugate of _D-biotin and _L-lysine, where the carboxylate of _D-biotin is coupled with the ?-amine of _L-lysine via a secondary amide bond. Biocytin is a classical neuroanatomical tracer commonly used to map brain connectivity. Biocytin is used as a versatile marker in anterograde, retrograde and intracellular neuroanatomical investigations and in biotinidase assays .

HY-118667

Dehydroergosterol	Microorganisms Source classification	Liposome
Dehydroergosterolis a naturally occurring fluorescent sterol analog (Ex/Em=325/375 nm), which mimics the properties of cholesterol in cell membranes. DehydroergosterolEasily conjugated by cholesterol-binding proteins for real-time imaging in live cells. DehydroergosterolThe sterol environment and intracellular sterol transport in vivo can be probed/elucidated in real time .

HY-N7497R

Protoescigenin (Standard)	Triterpenes Structural Classification other families Terpenoids Source classification Plants	Others
Protoescigenin (Standard) is the analytical standard of Protoescigenin. This product is intended for research and analytical applications. Protoescigenin is the main aglycone of horse chestnut saponin mixture known as escin. Protoescigenin is selected as substrate for exploratory chemistry towards selective protection, followed by propargyl ether formation and subsequent condensation with azido-monosaccharides, to obtain novel triazole linked conjugates of the triterpene .

HY-111974

β-D-Glucopyranosyl abscisate ABA-GE; (S)-cis,trans-Abscisic acid glucosyl ester	Structural Classification other families Classification of Application Fields Terpenoids Sesquiterpenes Source classification Abscisic acid Plants Phytohormone Disease Research Fields Endocrinology Agricultural Research	Proton Pump
β-D-Glucopyranosyl abscisate (ABA-GE) is a hydrolyzable abscisic acid (ABA) conjugate that accumulates in the vacuole and presumably also in the endoplasmic reticulum. The deconjugation of β-D-Glucopyranosyl abscisate allows the rapid formation of free ABA in response to abiotic stress conditions such as dehydration and salt stress. β-D-Glucopyranosyl abscisate contributes to the maintenance of ABA homeostasis .

HY-N11420

Coronatine	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Disease Research Fields Agricultural Research	Bacterial
Coronatine is a plant growth regulator produced by Pseudomonas syringae. Coronatine simulates bioactive jasmonic acid (HY-122464A) conjugates or octadecanoid signal molecules of higher plants to make plants appear pathogenic symptoms. Coronatine promotes the virulence of Pseudomonas syringae in plants by activating the signal cascade that inhibits the accumulation of Salicylic acid (HY-B0167) .

HY-121619

Jacaric acid	Structural Classification Caprifoliaceae Ketones, Aldehydes, Acids Source classification Plants Centranthus ruber (L.) DC	Apoptosis
Jacaric acid is a conjugated linolenic acid, which inhibits viability in cells PC-3 (IC₅₀ is 11.8 μM), LNCaP (IC₅₀ is 2.2 μM) and DLD-1, induces apoptosis and necrosis . Jacaric acid exhibits anticaner activity against prostate cancer and adenocarcinoma . Jacaric acid exhibits immunomodulating activity in murine peritoneal macrophages as an immunopotentiator . Jacaric acid is orally active.

HY-121624

Anthglutin	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Glutathione S-transferase
Anthglutin is a gamma-glutamyltransferase inhibitor isolated from Penicillium oxalicum cultures. The Ki values ??of Anthglutin for different enzymes are: porcine kidney enzyme 5.7 μM, human kidney enzyme 18.3 μM, human liver soluble enzyme 13.6 μM, and conjugated enzyme 10.2 μM. Anthglutin had no significant effect on intestinal absorption of methionine in rats .

HY-139066

Punicic acid Trichosanic acid	Structural Classification Punica granatum L. Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Punicaceae Plants Disease Research Fields	TNF Receptor GLUT Proteasome Tau Protein PKC
Punicic acid is a bioactive compound of pomegranate seed oil. Punicic acid is an isomer of conjugated α-linolenic acid and ω-5 polyunsaturated fatty acids. Punicic acid has anti-inflammatory and antioxidant activities and can inhibit the expression of inflammatory mediators such as tumor necrosis factor α (TNF-α). Punicic acid can also reduce the formation of β-amyloid deposits and hyperphosphorylation of tau by increasing the expression of GLUT4 protein and inhibiting the overactivation of calpain, and is used to prevent and treat neurodegenerative diseases. In addition, punicic acid also has breast cancer inhibitor properties that depend on lipid peroxidation and PKC pathways .

HY-W012952R

(2E,4E)-Hepta-2,4-dienal (Standard)	Structural Classification Natural Products Vaccinium macrocarpon Aiton Source classification Ericaceae Plants	Biochemical Assay Reagents
(2E,4E)-Hepta-2,4-dienal (Standard) is the analytical standard of (2E,4E)-Hepta-2,4-dienal. This product is intended for research and analytical applications. (2E,4E)-Hepta-2,4-dienal is a naturally occurring organic compound that belongs to the group of aldehydes. It is an unsaturated aldehyde with two conjugated double bonds, giving it unique chemical and physical properties. (2E,4E)-Hepta-2,4-dienal is commonly found in various plant sources, especially in spices such as parsley and coriander. It is used as a flavoring agent and food additive in the formulation of various foods such as baked goods, snacks and beverages. It is also used in the fragrance industry, especially in the production of perfume and cologne.

Cat. No.	Product Name	Chemical Structure

HY-N0324S2

Cholic acid-13C
Cholic acid- ¹³C is the ¹³C-labeled Cholic acid. Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion.

HY-N1420AS

Rhamnose-13C monohydrate
Rhamnose- ¹³C (monohydrate) is the ¹³C labeled Rhamnose monohydrate. Rhamnose monohydrate (L-Rhamnose monohydrate) is a monosaccharide found in plants and bacteria. Rhamnose monohydrate-conjugated immunogens is used in immunotherapies. Rhamnose monohydrate c

HY-N1420AS2

Rhamnose-13C-2 monohydrate
Rhamnose- ¹³C-2 (monohydrate) is the ¹³C labeled Rhamnose monohydrate. Rhamnose monohydrate (L-Rhamnose monohydrate) is a monosaccharide found in plants and bacteria. Rhamnose monohydrate-conjugated immunogens is used in immunotherapies. Rhamnose monohydrate

HY-Y1055S

Guanine-13C
Guanine- ¹³C is the ¹³C labeled Guanine[1]. Guanine (2-Aminohypoxanthine) is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds.

HY-Y1055S3

Guanine-15N5
Guanine- ¹⁵N₅ is ¹⁵N labeled Guanine (HY-Y1055). Guanine (2-Aminohypoxanthine) is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds.

HY-Y1055S4

Guanine-13C5
Guanine- ¹³C₅ is ¹³C-labeled Guanine (HY-Y1055). Guanine (2-Aminohypoxanthine) is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds.

HY-Y1055S1

Guanine-13C,15N2
Guanine- ¹³C, ¹⁵N₂ is the ¹³C and ¹⁵N labeled Guanine[1]. Guanine (2-Aminohypoxanthine) is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds.

HY-114360AS1

Taurohyodeoxycholic acid-d4 sodium
Taurohyodeoxycholic acid-d4 (sodium) is a deuterated labeled Taurohyodeoxycholic acid (sodium) . Taurohyodeoxycholic acid (THDCA) sodium is the taurine-conjugated form of the secondary bile acid hyodeoxycholic acid. Taurohyodeoxycholic acid can also reduce the activity and expression of myeloperoxidase TNF-α and IL-6, as well as colonic damage in TNBS-induced ulcerative colitis mouse model.

HY-Y1055S2

Guanine-13C5,15N5
Guanine- ¹³C₅, ¹⁵N₅ is ¹³C and ¹⁵N-labeled Guanine (HY-Y1055). Guanine (2-Aminohypoxanthine) is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds.

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