Search Result

Results for "

Carboxy Gliclazide-d<sub>4</sub>

" in MedChemExpress (MCE) Product Catalog:

By Targets:	P-glycoprotein (11) 11β-HSD (3) 5 alpha Reductase (4) 5-HT Receptor (65) Acetolactate Synthase (ALS) (1) ADC Cytotoxin (11) Adenosine Receptor (8) Adrenergic Receptor (77) AIM2 (1) Akt (4) Aldehyde Dehydrogenase (ALDH) (1) Amino Acid Derivatives (3) Aminopeptidase (1) AMPK (6) Amyloid-β (6) Anaplastic lymphoma kinase (ALK) (8) Androgen Receptor (17) Angiotensin Receptor (22) Angiotensin-converting Enzyme (ACE) (14) Antibiotic (157) Antifolate (5) Apical Sodium-Dependent Bile Acid Transporter (2) Apoptosis (226) Aryl Hydrocarbon Receptor (5) ATM/ATR (1) ATP Citrate Lyase (2) Aurora Kinase (1) Autophagy (260) Bacterial (232) Bcl-2 Family (4) Bcr-Abl (10) BCRP (2) Beta-lactamase (1) Beta-secretase (1) Biochemical Assay Reagents (16) Btk (4) c-Fms (2) c-Kit (15) c-Met/HGFR (5) Calcineurin (2) Calcium Channel (57) Cannabinoid Receptor (10) Carbonic Anhydrase (7) Casein Kinase (1) Caspase (6) CaSR (2) Cathepsin (1) CCR (1) CD73 (1) CDK (12) CFTR (5) Checkpoint Kinase (Chk) (1) Chloride Channel (2) Cholinesterase (ChE) (16) CMV (1) Complement System (5) COMT (5) COX (64) CRISPR/Cas9 (3) Cuproptosis (1) CXCR (1) Cyclophilin (2) Cytochrome P450 (30) Deubiquitinase (1) Dihydroorotate Dehydrogenase (1) Dipeptidyl Peptidase (14) DNA Alkylator/Crosslinker (8) DNA Methyltransferase (2) DNA Stain (2) DNA/RNA Synthesis (70) Dopamine Receptor (43) Drug Metabolite (62) Drug-Linker Conjugates for ADC (6) DYRK (2) E1/E2/E3 Enzyme (2) EBI2/GPR183 (1) EGFR (19) Elastase (1) Endogenous Metabolite (761) Endothelin Receptor (3) Enterovirus (5) Epigenetic Reader Domain (2) ERK (7) Estrogen Receptor/ERR (39) Factor Xa (4) FAK (1) Fatty Acid Synthase (FASN) (3) Ferroptosis (42) FGFR (11) FKBP (4) Flavivirus (2) FLT3 (7) Fluorescent Dye (26) Fungal (57) FXR (4) G protein-coupled Bile Acid Receptor 1 (2) G-quadruplex (1) GABA Receptor (25) Gap Junction Protein (2) Glucocorticoid Receptor (25) Glucosidase (1) Glucosylceramide Synthase (GCS) (2) Glutathione Reductase (1) Glutathione S-transferase (1) GlyT (2) GnRH Receptor (3) GPR35 (1) GPR55 (2) GSK-3 (3) HBV (8) HCV (17) HCV Protease (3) HDAC (17) Hedgehog (3) Hexokinase (1) HIF/HIF Prolyl-Hydroxylase (2) Histamine Receptor (32) Histone Acetyltransferase (6) Histone Demethylase (5) Histone Methyltransferase (3) HIV (53) HIV Integrase (11) HIV Protease (8) HMG-CoA Reductase (HMGCR) (15) HSP (4) HSV (13) IGF-1R (3) iGluR (20) IKK (2) Imidazoline Receptor (3) Indoleamine 2,3-Dioxygenase (IDO) (1) Influenza Virus (29) Insulin Receptor (1) Integrin (1) Interleukin Related (5) IRE1 (1) Isotope-Labeled Compounds (2006) JAK (7) JNK (1) Keap1-Nrf2 (10) Ketohexokinase (2) Kinesin (1) Leukotriene Receptor (10) Ligands for E3 Ligase (6) Ligands for Target Protein for PROTAC (1) Liposome (2) Lipoxygenase (3) LPL Receptor (6) mAChR (35) MDM-2/p53 (3) MEK (3) Melanocortin Receptor (1) Melatonin Receptor (9) mGluR (10) MicroRNA (1) Microtubule/Tubulin (18) Mineralocorticoid Receptor (10) Mitochondrial Metabolism (6) Mitophagy (39) MMP (5) Molecular Glues (9) Monoamine Oxidase (8) Monoamine Transporter (1) mTOR (2) Myosin (4) Na+/K+ ATPase (5) nAChR (11) NADPH Oxidase (1) Neprilysin (7) Neurokinin Receptor (3) NF-κB (30) NO Synthase (21) NOD-like Receptor (NLR) (3) Notch (7) Nuclear Hormone Receptor 4A/NR4A (2) Nucleoside Antimetabolite/Analog (57) Opioid Receptor (3) Orexin Receptor (OX Receptor) (1) Orthopoxvirus (12) Oxidative Phosphorylation (1) P2X Receptor (1) P2Y Receptor (7) p38 MAPK (3) PAK (7) Parasite (64) PARP (4) PDGFR (19) PGE synthase (1) Phosphatase (8) Phosphodiesterase (PDE) (21) Phospholipase (5) PI3K (3) PKA (2) PKC (7) Potassium Channel (28) PPAR (22) Progesterone Receptor (25) Prostaglandin Receptor (21) PROTAC Linkers (7) Protease Activated Receptor (PAR) (1) Proteasome (1) Proton Pump (21) RABV (1) Raf (7) RAR/RXR (5) Ras (2) Reactive Oxygen Species (39) Renin (2) RET (6) Reverse Transcriptase (8) ROS Kinase (5) RSV (7) SARS-CoV (39) Ser/Thr Protease (2) Serotonin Transporter (24) SGLT (6) Sigma Receptor (1) Sirtuin (6) Small Interfering RNA (siRNA) (1) Sodium Channel (26) Src (5) STAT (5) Syk (1) TAM Receptor (3) Tau Protein (1) TGF-beta/Smad (5) Thrombin (9) Thrombopoietin Receptor (3) Thymidylate Synthase (5) Thyroid Hormone Receptor (6) TNF Receptor (5) Toll-like Receptor (TLR) (4) TOPK (1) Topoisomerase (22) Trk Receptor (3) TRP Channel (16) Tyrosinase (6) Vasopressin Receptor (1) VD/VDR (14) VEGFR (25) Virus Protease (15) Wee1 (1) Xanthine Oxidase (3) β-catenin (4) γ-secretase (1)
By Research Areas:	Cancer (742) Cardiovascular Disease (219) Endocrinology (186) Infection (390) Inflammation/Immunology (325) Metabolic Disease (363) Neurological Disease (387)
Click Chemistry:	Azide (3) Alkynes (14)
Oligonucleotides:	Release-retarding Agents (3) Nucleosides and their Analogs (1) Pre-designed siRNA Sets (1) Suspending Agents (1) Emulsifiers (1) siRNAs (1)

3052

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

2901

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Oligonucleotides

Targets Recommended: P-glycoprotein

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0753S

Gliclazide-d4	Potassium Channel	Cardiovascular Disease
Gliclazide-d₄ (S1702 D4) is the deuterium labeled Gliclazide. Gliclazide (S1702) is a whole-cell beta-cell ATP-sensitive potassium currents blocker with an IC50 of 184 nM. Gliclazide is used as an antidiabetic[1].

HY-66005S

Acetaminophen-d4 Paracetamol-d<sub>4sub>; 4-Acetamidophenol-d<sub>4sub>; 4'-Hydroxyacetanilide-d<sub>4sub>	COX Histone Acetyltransferase Endogenous Metabolite	Inflammation/Immunology
Acetaminophen-d₄ is the deuterium labeled Acetaminophen. Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM; is a widely used antipyretic and analgesic agent[1][2][3]. Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor[4].

HY-132617S

Carboxy Gliclazide-d4	Drug Metabolite	Infection
Carboxy Gliclazide-d₄ is the deuterium labeled Carboxy Gliclazide[1].

HY-133675S

*Mono(5-carboxy-2-ethylpentyl) phthalate-d4* MECPP-d<sub>4sub>	Isotope-Labeled Compounds	Others
Mono(5-carboxy-2-ethylpentyl) phthalate-d₄ (MECPP-d₄) is a deuterium labeled Mono(5-carboxy-2-ethylpentyl) phthalate (HY-133675). Mono(5-carboxy-2-ethylpentyl) phthalate (MECPP) is a metabolite of Di-(2-ethylhexyl) phthalate (DEHP). Di(2-ethylhexyl) phthalate is the predominant plasticizer added to rigid polyvinyl chloride (PVC) to impart flexibility, temperature tolerance, optical clarity, strength and resistance to kinking .

HY-RS13999

SUB1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SUB1 Human Pre-designed siRNA Set A contains three designed siRNAs for SUB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SUB1 Human Pre-designed siRNA Set A SUB1 Human Pre-designed siRNA Set A

HY-146227

DNA topoisomerase II inhibitor 1	Topoisomerase Apoptosis	Cancer
DNA topoisomerase II inhibitor 1 (compound 8ed) is a potent DNA topoisomerase II inhibitor. DNA topoisomerase II inhibitor 1 shows anti-proliferative activity. DNA topoisomerase II inhibitor 1 induces apoptosis and cell cycle arrest at sub G1 phase .

HY-10844S1

Pretomanid-d5 PA-824-d<sub>5sub>; (S)-PA 824-d<sub>5sub>	Antibiotic Bacterial Isotope-Labeled Compounds	Infection Cancer
Pretomanid-d₅ is deuterated labeled Pretomanid (HY-10844). Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 μg/mL.

HY-113879

*18-Carboxy* dinor Leukotriene B4** 18-Carboxy dinor LTB4	Others	Metabolic Disease
18-Carboxy dinor Leukotriene B4 (18-carboxy dinor LTB4) is a β-oxidation metabolite of LTB4. In the liver, LTB4 is rapidly metabolized to 20-carboxy LTB4, which then undergoes β-oxidation to 18-carboxy dinor LTB4.

HY-W424779R

*5-Carboxy-2′-deoxyuridine (Standard)*	Drug Metabolite	Infection
5-Carboxy-2′-deoxyuridine (Standard) is the analytical standard of 5-Carboxy-2′-deoxyuridine. This product is intended for research and analytical applications. 5-Carboxy-2′-deoxyuridine is a metabolite of Trifluridine . 5-Carboxy-2′-deoxyuridine is a methyl oxidation product of Thymidine that can be formed by menadione-mediated photosensitization of Thymidine .

HY-41680S

4-Aminobenzonitrile-d4 4-Aminobenzonitrile-d<sub>4sub>; 4-Cyanoaniline-d<sub>4sub>; 4-Cyanobenzenamine-d<sub>4sub>	Isotope-Labeled Compounds	Others
4-Aminobenzonitrile-d₄ is the deuterium labeled 4-Aminobenzonitrile[1].

HY-W424779

*5-Carboxy-2′-deoxyuridine*	Drug Metabolite	Infection
5-Carboxy-2′-deoxyuridine is a metabolite of Trifluridine . 5-Carboxy-2′-deoxyuridine is a methyl oxidation product of Thymidine that can be formed by menadione-mediated photosensitization of Thymidine .

HY-132636S

*(Rac)-5-Carboxy* Tolterodine-d14**	Isotope-Labeled Compounds	Others
(Rac)-5-Carboxy Tolterodine-d₁₄ is the deuterium labeled (Rac)-5-Carboxy Tolterodine[1].

HY-142842S

Carboxy primaquine-d4	Isotope-Labeled Compounds	Others
Carboxy primaquine-d₄ is the deuterium labeled Carboxy primaquine[1].

HY-W023023

*3-Carboxy-6-hydroxycoumarin*	Others	Others
3-Carboxy-6-hydroxycoumarin is an intermediate in organic syntheses .

HY-Y1042S

4-Cyanophenol-d4 4-Hydroxybenzonitrile-d<sub>4sub>; 4-Hydroxycyanobenzene-d<sub>4sub>; NSC 400524-d<sub>4sub>	Isotope-Labeled Compounds	Others
4-Cyanophenol-d₄ is the deuterium labeled 4-Cyanophenol[1].

HY-D0114

*3-Carboxy-7-Hydroxycoumarin*	Fluorescent Dye	Others
3-Carboxy-7-Hydroxycoumarin is a UV-light excitable fluorescent dye .

HY-D2183

*6-Carboxy-JF5252*	Fluorescent Dye	Others
6-Carboxy-JF5252 is a fluorophore. 6-Carboxy-JF5252 can be used as probes, dyes, tags. 6-Carboxy-JF5252 can be used for the research of super-resolution imaging .

HY-D0054

*9-(2-Carboxy-2-cyanovinyl)julolidine*	Fluorescent Dye	Inflammation/Immunology
9-(2-Carboxy-2-cyanovinyl)julolidine is a fluorescent molecular rotor. 9-(2-Carboxy-2-cyanovinyl)julolidine can be used to bind to IgG and Fab, and preparing antibodies .

HY-17413S2

Zidovudine-d4 Azidothymidine-d<sub>4sub>; AZT-d<sub>4sub>; ZDV-d<sub>4sub>	CRISPR/Cas9 HIV Isotope-Labeled Compounds	Infection Cancer
Zidovudine-d₄ is deuterated labeled Zidovudine (HY-17413). Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection. Zidovudine increases CRISPR/Cas9-mediated editing frequency.

HY-B1008S

4-Aminobenzoic acid-d4 PABA-d<sub>4sub>; Vitamin Bx-d<sub>4sub>; Vitamin H1-d<sub>4sub>; p-Aminobenzoic acid-d<sub>4sub>	Isotope-Labeled Compounds Endogenous Metabolite	Others
4-Aminobenzoic acid-d₄ is the deuterium labeled 4-Aminobenzoic acid. 4-Aminobenzoic acid is an intermediate in the synthesis of folate by bacteria, plants, and fungi.

HY-18734A

Carboxy-PTIO potassium 4 Publications Verification	NO Synthase	Cardiovascular Disease Metabolic Disease Inflammation/Immunology
Carboxy-PTIO potassium is a potent nitric oxide (NO) scavenger that can make a quick reaction with NO to produce NO₂. Carboxy-PTIO potassium can prevent hypotension and endotoxic shock through the direct scavenging action against NO in lipopolysaccharide-stimulated rat model .

HY-18734

Carboxy-PTIO	NO Synthase	Cardiovascular Disease Metabolic Disease Inflammation/Immunology
Carboxy-PTIO is a potent nitric oxide (NO) scavenger that can make a quick reaction with NO to produce NO₂. Carboxy-PTIO can prevent hypotension and endotoxic shock through the direct scavenging action against NO in lipopolysaccharide-stimulated rat model .

HY-N0006S1

Demethoxycurcumin-d4 Curcumin II-d<sub>4sub>; Desmethoxycurcumin-d<sub>4sub>; Monodemethoxycurcumin-d<sub>4sub>	Apoptosis Autophagy Bacterial	Cancer
Demethoxycurcumin-d₄ is the deuterium labeled Demethoxycurcumin. Demethoxycurcumin (Curcumin II) is a major active curcuminoid; possess anti-inflammatory properties[1].

HY-W739812

Carboxy finasteride Finasteride Carboxylic acid	Others	Cancer
Carboxy finasteride is a metabolite of the 5α-reductase inhibitor Finasteride (HY-13635). Finasteride is biotransformed by cytochrome P450 (CYP3A4) and is successively oxidized to Hydroxy finasteride and Carboxy finasteride. Carboxy finasteride is the major metabolite in urine, while Hydroxy finasteride is the major metabolite in plasma .

HY-W141955

*γ-Carboxy-DL-glutamic acid*	Amino Acid Derivatives	Others
γ-Carboxy-DL-glutamic acid is a glutamic acid derivative. γ-Carboxy-DL-glutamic acid is optically active .

HY-B0329S

Isoniazid-d4 INH-d<sub>4sub>; Isonicotinic acid hydrazide-d<sub>4sub>; Isonicotinic hydrazide-d<sub>4sub>	Bacterial Autophagy Mitophagy Antibiotic	Infection
Isoniazid-d₄ is the deuterium labeled Isoniazid. Isoniazid (INH) is a proagent and must be activated by a bacterial catalase-peroxidase enzyme KatG. Isoniazid is bactericidal to rapidly dividing mycobacteria and has anti-tuberculostatic activity[1][2][3][4].

HY-100048S

Acetylisoniazid-d4 Acetylisoniazide-d<sub>4sub>; N-Monoacetylisoniazid-d<sub>4sub>; NSC 36084-d<sub>4sub>	Isotope-Labeled Compounds	Others
Acetylisoniazid-d₄ is the deuterium labeled Acetylisoniazid[1].

HY-118861S

Enclomiphene-d4 hydrochloride (E)-Clomiphene-d<sub>4sub> hydrochloride; trans-Clomiphene-d<sub>4sub> hydrochloride; Enclomifene-d<sub>4sub> hydrochloride	Isotope-Labeled Compounds Estrogen Receptor/ERR	Inflammation/Immunology
Enclomiphene-d₄ (hydrochloride) is a deuterium labeled Enclomiphene. Enclomiphene-d₄ (hydrochloride) is a potent and orally active oestrogen receptor antagonist, with antioestrogenic property[1].

HY-109015S

Tucidinostat-d4 Chidamide-d<sub>4sub>; HBI-8000-d<sub>4sub>; CS 055-d<sub>4sub>	Isotope-Labeled Compounds HDAC	Cancer
Tucidinostat-d₄ is the deuterium labeled Tucidinostat. Tucidinostat is a potent and orally bioavailable HDAC enzymes class I (HDAC1/2/3) and class IIb (HDAC10) inhibitor, with IC50s of 95, 160, 67 and 78 nM, respectively[1].

HY-19696AS

Tauroursodeoxycholate-d4 sodium Tauroursodeoxycholic acid-d<sub>4sub> sodium; TUDCA-d<sub>4sub> sodium; UR 906-d<sub>4sub> sodium	Isotope-Labeled Compounds ERK Caspase Apoptosis Endogenous Metabolite	Cancer
Tauroursodeoxycholate-d₄ (sodium) is the deuterium labeled Tauroursodeoxycholate sodium. Tauroursodeoxycholate (Tauroursodeoxycholic acid; TUDCA) sodium is an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12. Tauroursodeoxycholate also inhibits ERK.

HY-19696S1

Tauroursodeoxycholate-d4 Tauroursodeoxycholic acid-d<sub>4sub>; TUDCA-d<sub>4sub>; UR 906-d<sub>4sub>	Isotope-Labeled Compounds ERK Caspase Endogenous Metabolite Apoptosis	Cancer
Tauroursodeoxycholate-d₄ is deuterium labeled Tauroursodeoxycholate. Tauroursodeoxycholate (Tauroursodeoxycholic acid) is an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12. Tauroursodeoxycholate also inhibits ERK.

HY-B0389S24

D-Glucose-d4 Glucose-d<sub>4sub>; D-(+)-Glucose-d<sub>4sub>; Dextrose-d<sub>4sub>	Endogenous Metabolite	Metabolic Disease Cancer
D-Glucose-d₄ is the deuterium labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molec

HY-B0696AS

Tiagabine-d4 hydrochloride NO050328-dd<sub>4sub> hydrochloride; NO328-d<sub>4sub> hydrochloride; TGB-d<sub>4sub> hydrochloride	GABA Receptor Isotope-Labeled Compounds	Neurological Disease
Tiagabine-d₄ hydrochloride is deuterated labeled Tiagabine hydrochloride (HY-B0696A). Tiagabine hydrochloride is a potent and selective GABA reuptake inhibitor, used as an anticonvulsant agent, with IC₅₀s of 67, 446 and 182 nM for [ ³H]GABA uptake in Synaptosomes, Neurons and Glia, respectively .

HY-13273S

Ostarine-d4 MK-2866-d<sub>4sub>; GTX-024-d<sub>4sub>; Enobosarm-d<sub>4sub>	Isotope-Labeled Compounds Androgen Receptor	Cancer
Ostarine-d4 is a deuterated labeled Ostarine .

HY-W588299S

*Mono-(7-carboxy-4-methylheptyl) phthalate-d4*	Isotope-Labeled Compounds	Others
Mono-(7-carboxy-4-methylheptyl) phthalate-d4 is a deuterated labeled Mono-(7-carboxy-4-methylheptyl) phthalate .

HY-D1078

*5(6)-Carboxy-2',7'-dichlorofluorescein diacetate*	Reactive Oxygen Species	Others
5(6)-Carboxy-2',7'-dichlorofluorescein diacetate is a cell permeant fluorescent indicator. 5(6)-Carboxy-2',7'-dichlorofluorescein diacetate can be used to assess reactive oxygen species (ROS) generation within human neuronal-glial (HNG) cells in primary co-culture

HY-N8139

*2-Amino-3-carboxy-1,4-naphthoquinone*	Others	Metabolic Disease
2-Amino-3-carboxy-1,4-naphthoquinone is the electron transfer mediator. 2-Amino-3-carboxy-1,4-naphthoquinone changes glucose metabolism of the homofermentative lactic acid bacteria .

HY-34498S

4-Chloro-2-methylphenol-d4 4-Chloro-o-cresol-d<sub>4sub>; 4-Chlorocresol-d<sub>4sub>; 5-Chloro-2-hydroxytoluene-d<sub>4sub>	Isotope-Labeled Compounds	Others
4-Chloro-2-methylphenol-d₄ is the deuterium labeled 4-Chloro-2-methylphenol[1].

HY-107542S

Oleoylethanolamide-d4 N-Oleoylethanolamide-d<sub>4sub>; Oleamide MEA-d<sub>4sub>; Oleic acid monoethanolamide-d<sub>4sub>	Isotope-Labeled Compounds Endogenous Metabolite PPAR	Cardiovascular Disease Metabolic Disease
Oleoylethanolamide-d₄ is the deuterium labeled Oleoylethanolamide. Oleoylethanolamide is a high affinity endogenous PPAR-α agonist, which plays an important role in the treatment of obesity and arteriosclerosis.

HY-B0017S

Telbivudine-d4 Epavudine-d<sub>4sub>; L-Thymidine-d<sub>4sub>; NV 02B-d<sub>4sub>	Isotope-Labeled Compounds HBV	Infection
Telbivudine-d₄ is deuterium labeled Telbivudine. Telbivudine (Epavudine), an orally active thymidine nucleoside analog, is a potent antiviral inhibitor of hepatitis B virus (HBV) replication[1].

HY-B0579S

Cyclosporin A-d4 Cyclosporine A-d<sub>4sub>; Ciclosporin A-d<sub>4sub>; CsA-d<sub>4sub>	Antibiotic Complement System Phosphatase	Inflammation/Immunology Cancer
Cyclosporin A-d₄ is the deuterium labeled Cyclosporin A. Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of calcineurin with an IC50 of 5 nM. Cyclosporin A also inhibits CD11a/CD18 ad

HY-N5034S

Phosphorylethanolamine-d4 Monoaminoethyl phosphate-d<sub>4sub>; NSC 254167-d<sub>4sub>; O-Phosphoethanolamine-d<sub>4sub>	Isotope-Labeled Compounds	Metabolic Disease
Phosphorylethanolamine-d₄ (Monoaminoethyl phosphate-d₄; NSC 254167-d₄) is a deuterium labeled Phosphorylethanolamine (HY-N5034). Phosphorylethanolamine is an endogenous metabolite.

HY-16582AS

Sonidegib-d4 Erismodegib-d<sub>4sub>; LDE225-d<sub>4sub>; NVP-LDE225-d<sub>4sub>	Isotope-Labeled Compounds	Others
Sonidegib-d4 is a isotope of Sonidegib. Sonidegib is a potent and selective Smo antagonist with IC₅₀ of 1.3 nM and 2.5 nM for mouse and human Smo in binding assay, respectively .

HY-10581AS1

Gatifloxacin-d4 hydrochloride AM-1155-d<sub>4sub> hydrochloride; BMS-206584-d<sub>4sub> hydrochloride; PD135432-d<sub>4sub> hydrochloride	Antibiotic Bacterial Topoisomerase Isotope-Labeled Compounds	Infection
Gatifloxacin-d₄ (AM-1155-d₄; BMS-206584-d₄; PD135432-d₄) hydrochloride is deuterium-labeled Gatifloxacin (hydrochloride) (HY-10581A) .

HY-W700069

Gatifloxacin-d4 AM-1155-d<sub>4sub>; BMS-206584-d<sub>4sub>; PD135432-d<sub>4sub>	Isotope-Labeled Compounds	Others
Gatifloxacin-d4 is the deuterium labeled Gatifloxacin .

HY-78004S1

1,2-Diphenylethane-d4 Dibenzil-d<sub>4sub>; s-Diphenylethane-d<sub>4sub>; Bibenzyl-d<sub>4sub>	Isotope-Labeled Compounds	Others
1,2-Diphenylethane-d4 (Dibenzil-d4; s-Diphenylethane-d4; Bibenzyl-d4) is the deuterium labeled Bibenzyl (HY-78004) .

HY-17422S1

Acyclovir-d4 Aciclovir-d<sub>4sub>; Acycloguanosine-d<sub>4sub>	Isotope-Labeled Compounds HSV Bacterial Apoptosis Antibiotic	Infection Cancer
Acyclovir-d₄ is the deuterium labeled Acyclovir. Acyclovir (Aciclovir) is a guanosine analogue and an orally active antiviral agent. Acyclovir inhibits HSV-1 (IC50 of 0.85 μM), HSV-2 (IC50 of 0.86 μM) and varicella-zoster virus. Acyclovir can be phosphorylated by viral thymidine kinase (TK), and Acyclovir triphosphate interferes with viral DNA polymerization through competitive inhibition with guanosine triphosphate and obligatory chain termination[1][2][3]. Acyclovir prevents bacterial infections during induction therapy for acute leukaemia[4].

HY-B0548AS1

Hydroxyzine-d4' dihydrochloride Vistaril-d<sub>4sub>' dihydrochloride; Atarax-dd<sub>4sub>' dihydrochloride	Histamine Receptor	Inflammation/Immunology Endocrinology
Hydroxyzine-d₄ (dihydrochloride) is the deuterium labeled Hydroxyzine dihydrochloride. Hydroxyzine dihydrochloride, a benzodiazepine antihistamine agent, acts as a orally active histamine H1-receptor and serotonin antagonist. Hydroxyzine dihydrochloride has anxiolytic effect and can be used forthe research of generalised anxiety disorder[1][2].

HY-B0035S

Sulfamethazine-d4 Sulfadimidine-d<sub>4sub>; Sulfadimerazine-d<sub>4sub>	Bacterial	Infection
Sulfamethazine-d₄ is a deuterium labeled Sulfamethazine (Sulfadimidine). Sulfamethazine is an antimicrobial that is widely used to treat and prevent various animal diseases (such as gastrointestinal and respiratory tract infections)[1][2].

HY-B1217S

Bronopol-d4 BNPD-d<sub>4sub>; BNPK-d<sub>4sub>	Isotope-Labeled Compounds Bacterial	Infection
Bronopol-d₄ is deuterium labeled Bronopol.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N8139

*2-Amino-3-carboxy-1,4-naphthoquinone*	Alkaloids Quinones Classification of Application Fields Source classification Rubiaceae Metabolic Disease Plants Naphthalene Quinones Disease Research Fields Rubia cordifolia L.	Others
2-Amino-3-carboxy-1,4-naphthoquinone is the electron transfer mediator. 2-Amino-3-carboxy-1,4-naphthoquinone changes glucose metabolism of the homofermentative lactic acid bacteria .

HY-125833

Alpha-Naphthoflavone 5+ Cited Publications	Flavonoids Flavones Source classification Indigofera heterantha Wall. ex Brand. Plants Compositae Disease Research Fields Cancer	Cytochrome P450 Aryl Hydrocarbon Receptor Apoptosis
Alpha-Naphthoflavone is an orally active flavonoid that is a potent, competitive inhibitor of aromatase< b>aromatase. < b > IC < sub > 50 < / sub > < / b > and < b > K < sub > I < / sub > < / b > value were 0.5 and 0.2 microns. Alpha-Naphthoflavone can inhibit cell proliferation and induce apoptosis ^[4].

HY-W751835

Baloxavir-d4 Maximum Cited Publications 30 Publications Verification Baloxavir acid-d<sub>4sub>; S-033447-d<sub>4sub>	Classification of Application Fields Disease Research Fields Cancer	Isotope-Labeled Compounds
Baloxavir-d₄ (Baloxavir acid-d₄; S-033447-d₄) is the deuterium-labeled Baloxavir (HY-109025A). Baloxavir-d₄ (Baloxavir-d₄ acid), derived from the proagent Baloxavir-d₄ marboxil, is a first-in-class, potent and selective cap-dependent endonuclease (CEN) inhibitor within the polymerase PA subunit of influenza A and B viruses. Baloxavir-d₄ inhibits viral RNA transcription and replication and has potently antiviral activity .

HY-W011474

Geranylgeraniol	Structural Classification Natural Products Microorganisms	NF-κB
Geranylgeraniol is an orally acitve vitamin K₂ sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model ^[4].

HY-P2274

Argifin	Infection Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields	Parasite
Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms, with IC₅₀s of 0.025 μM, 6.4 μM , 1.1 μM and 4.5 μM for SmChiA (Serratia marcescens chitinaese A), SmChiB, Aspergillus fumigatus chitinase B1 and human chitotriosidase, respectively .

HY-N0662

Amentoflavone 5+ Cited Publications Didemethyl-ginkgetin	Structural Classification Flavonoids Classification of Application Fields Source classification Phenols Polyphenols Selaginellaceae Plants Biflavones Selaginella tamariscina (P. Beauv.) Spring Disease Research Fields Cancer	Reactive Oxygen Species Apoptosis Bacterial Fungal RSV GABA Receptor
Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active GABA(A) negative modulator. Amentoflavone also shows anti-inflammatory, antioxidative, anti-viral, anti-tumor, anti-radiation, anti-fungal, antibacterial activity. Amentoflavone induces apoptosis and cell cycle arrest at sub-G1 phase ^[4].

HY-P99294

Ganitumab AMG 479; Human Anti-IGF1R Recombinant Antibody	Classification of Application Fields Disease Research Fields Cancer	IGF-1R
Ganitumab (AMG 479) is a recombinant human monoclonal antibody to the human type 1 insulin-like growth factor receptor (IGF1R). Ganitumab recognizes murine IGF1R with sub-nanomolar affinity (K_D=0.22 nM) and inhibits the interaction of murine IGF1R with IGF1 and IGF2. Ganitumab can be used in research of cancer .

HY-N11799

Neochilenin 3-O-Methylquercetin 4′-O-glucoside	Structural Classification Flavonoids Source classification Plants Compositae Other Flavonoids	Others
Neochilenin (3-O-Methylquercetin 4 '-O-glucoside) is a glycoside of 3-O-methylquercetin, which can be isolated from the sub-family Cereoideae (Cactaceae). .

HY-N10192

Aculene D	Infection Microorganisms Classification of Application Fields Terpenoids Sesquiterpenes Source classification Disease Research Fields	Endogenous Metabolite Bacterial
Aculene D, a fungal metabolite, shows quorum sensing (QS) inhibitory activity against Chromobacterium violaceum CV026, and could significantly reduce violacein production in N-hexanoyl-l-homoserine lactone (C6-HSL) induced C. violaceum CV026 cultures at sub-inhibitory concentrations .

HY-W011474R

Geranylgeraniol (Standard)	Structural Classification Natural Products Microorganisms	NF-κB
Geranylgeraniol (Standard) is the analytical standard of Geranylgeraniol. This product is intended for research and analytical applications. Geranylgeraniol is an orally acitve vitamin K2 sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model ^[3][4].

HY-N0662R

Amentoflavone (Standard)	Structural Classification Flavonoids Source classification Phenols Polyphenols Selaginellaceae Plants Biflavones Selaginella tamariscina (P. Beauv.) Spring	Reactive Oxygen Species Apoptosis Bacterial Fungal RSV GABA Receptor
Amentoflavone (Standard) is the analytical standard of Amentoflavone. This product is intended for research and analytical applications. Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active GABA(A) negative modulator. Amentoflavone also shows anti-inflammatory, antioxidative, anti-viral, anti-tumor, anti-radiation, anti-fungal, antibacterial activity. Amentoflavone induces apoptosis and cell cycle arrest at sub-G1 phase ^[4].

HY-B0504S

Creatinine-d3 3 Publications Verification NSC13123-d<sub>3sub>	Classification of Application Fields Metabolic Disease Disease Research Fields	Endogenous Metabolite
Creatinine-d₃ is a deuterium labeled Creatinine. Creatinine is a break-down product of creatine phosphate in muscle[1].

HY-133154

Carboxyaminoimidazole ribotide CAIR; 4-Carboxy-AIR	Infection Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Carboxyaminoimidazole ribotide (CAIR) is a metabolite of E. coli. Carboxyaminoimidazole ribotide can be used to detect distinctive features of E. coli PurE active site and synthesis fungal de novo purine .

HY-W001084

Methyl 4-hydroxyphenylacetate	Monophenols Microorganisms Classification of Application Fields Source classification Other Diseases Phenols Disease Research Fields	Others
Methyl 4-hydroxyphenylacetate, a natural compound, is a methyl ester resulting from the formal condensation of the carboxy group of 4-Hydroxyphenylacetic acid with methanol .

HY-W004289

Methyl pentadecanoate	Structural Classification Natural Products other families Classification of Application Fields Source classification Other Diseases Plants Disease Research Fields	Others
Methyl pentadecanoate is a fatty acid ester, can be isolated from L. wallichi extracts. Methyl pentadecanoate is obtained by condensation of the carboxy group of pentadecanoic acid with the hydroxy group of methanol .

HY-B0710

Betaine 3 Publications Verification Trimethylglycine; Carboxy-N,N,N-trimethylmethanaminium	Structural Classification Natural Products Microorganisms other families Animals Classification of Application Fields Disease markers Metabolic Disease Plants Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite
Betaine (Trimethylglycine) is a natural compound found in many foods and also an active methyl-donor which can maintain normal DNA methylation patterns ^[1,2]. Betaine is found ubiquitously in plants, animals, microorganisms, and rich dietary sources including seafood, spinach, and wheat bran. Betaine also acts as an osmolyte, to maintain the avian’s cellular water and ion balance to improve the avian’s capacity against heat stress via preventing dehydration and osmotic inactivation. It helps in maintaining the protective osmolytic activity, especially in heat-stressed birds. Betaine may promote various intestinal microbes against osmotic variations and thus improve microbial fermentation activity .

Cat. No.	Product Name	Chemical Structure

HY-B0753S

Gliclazide-d4
Gliclazide-d₄ (S1702 D4) is the deuterium labeled Gliclazide. Gliclazide (S1702) is a whole-cell beta-cell ATP-sensitive potassium currents blocker with an IC50 of 184 nM. Gliclazide is used as an antidiabetic[1].

HY-66005S

Acetaminophen-d4
Acetaminophen-d₄ is the deuterium labeled Acetaminophen. Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM; is a widely used antipyretic and analgesic agent[1][2][3]. Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor[4].

HY-Y1042S

4-Cyanophenol-d4
4-Cyanophenol-d₄ is the deuterium labeled 4-Cyanophenol[1].

HY-132617S

Carboxy Gliclazide-d4
Carboxy Gliclazide-d₄ is the deuterium labeled Carboxy Gliclazide[1].

HY-133675S

Mono(5-carboxy-2-ethylpentyl) phthalate-d4

Mono(5-carboxy-2-ethylpentyl) phthalate-d₄ (MECPP-d₄) is a deuterium labeled Mono(5-carboxy-2-ethylpentyl) phthalate (HY-133675). Mono(5-carboxy-2-ethylpentyl) phthalate (MECPP) is a metabolite of Di-(2-ethylhexyl) phthalate (DEHP). Di(2-ethylhexyl) phthalate is the predominant plasticizer added to rigid polyvinyl chloride (PVC) to impart flexibility, temperature tolerance, optical clarity, strength and resistance to kinking .

HY-10844S1

Pretomanid-d5
Pretomanid-d₅ is deuterated labeled Pretomanid (HY-10844). Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 μg/mL.

HY-41680S

4-Aminobenzonitrile-d4
4-Aminobenzonitrile-d₄ is the deuterium labeled 4-Aminobenzonitrile[1].

HY-132636S

*(Rac)-5-Carboxy* Tolterodine-d14**
(Rac)-5-Carboxy Tolterodine-d₁₄ is the deuterium labeled (Rac)-5-Carboxy Tolterodine[1].

HY-142842S

Carboxy primaquine-d4
Carboxy primaquine-d₄ is the deuterium labeled Carboxy primaquine[1].

HY-17413S2

Zidovudine-d4
Zidovudine-d₄ is deuterated labeled Zidovudine (HY-17413). Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection. Zidovudine increases CRISPR/Cas9-mediated editing frequency.

HY-B1008S

4-Aminobenzoic acid-d4
4-Aminobenzoic acid-d₄ is the deuterium labeled 4-Aminobenzoic acid. 4-Aminobenzoic acid is an intermediate in the synthesis of folate by bacteria, plants, and fungi.

HY-N0006S1

Demethoxycurcumin-d4
Demethoxycurcumin-d₄ is the deuterium labeled Demethoxycurcumin. Demethoxycurcumin (Curcumin II) is a major active curcuminoid; possess anti-inflammatory properties[1].

HY-B0329S

Isoniazid-d4
Isoniazid-d₄ is the deuterium labeled Isoniazid. Isoniazid (INH) is a proagent and must be activated by a bacterial catalase-peroxidase enzyme KatG. Isoniazid is bactericidal to rapidly dividing mycobacteria and has anti-tuberculostatic activity[1][2][3][4].

HY-100048S

Acetylisoniazid-d4
Acetylisoniazid-d₄ is the deuterium labeled Acetylisoniazid[1].

HY-118861S

Enclomiphene-d4 hydrochloride
Enclomiphene-d₄ (hydrochloride) is a deuterium labeled Enclomiphene. Enclomiphene-d₄ (hydrochloride) is a potent and orally active oestrogen receptor antagonist, with antioestrogenic property[1].

HY-109015S

Tucidinostat-d4
Tucidinostat-d₄ is the deuterium labeled Tucidinostat. Tucidinostat is a potent and orally bioavailable HDAC enzymes class I (HDAC1/2/3) and class IIb (HDAC10) inhibitor, with IC50s of 95, 160, 67 and 78 nM, respectively[1].

HY-19696AS

Tauroursodeoxycholate-d4 sodium
Tauroursodeoxycholate-d₄ (sodium) is the deuterium labeled Tauroursodeoxycholate sodium. Tauroursodeoxycholate (Tauroursodeoxycholic acid; TUDCA) sodium is an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12. Tauroursodeoxycholate also inhibits ERK.

HY-19696S1

Tauroursodeoxycholate-d4
Tauroursodeoxycholate-d₄ is deuterium labeled Tauroursodeoxycholate. Tauroursodeoxycholate (Tauroursodeoxycholic acid) is an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12. Tauroursodeoxycholate also inhibits ERK.

HY-B0389S24

D-Glucose-d4
D-Glucose-d₄ is the deuterium labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molec

HY-B0696AS

Tiagabine-d4 hydrochloride
Tiagabine-d₄ hydrochloride is deuterated labeled Tiagabine hydrochloride (HY-B0696A). Tiagabine hydrochloride is a potent and selective GABA reuptake inhibitor, used as an anticonvulsant agent, with IC₅₀s of 67, 446 and 182 nM for [ ³H]GABA uptake in Synaptosomes, Neurons and Glia, respectively .

HY-13273S

Ostarine-d4
Ostarine-d4 is a deuterated labeled Ostarine .

HY-W588299S

*Mono-(7-carboxy-4-methylheptyl) phthalate-d4*
Mono-(7-carboxy-4-methylheptyl) phthalate-d4 is a deuterated labeled Mono-(7-carboxy-4-methylheptyl) phthalate .

HY-34498S

4-Chloro-2-methylphenol-d4
4-Chloro-2-methylphenol-d₄ is the deuterium labeled 4-Chloro-2-methylphenol[1].

HY-107542S

Oleoylethanolamide-d4
Oleoylethanolamide-d₄ is the deuterium labeled Oleoylethanolamide. Oleoylethanolamide is a high affinity endogenous PPAR-α agonist, which plays an important role in the treatment of obesity and arteriosclerosis.

HY-B0017S

Telbivudine-d4
Telbivudine-d₄ is deuterium labeled Telbivudine. Telbivudine (Epavudine), an orally active thymidine nucleoside analog, is a potent antiviral inhibitor of hepatitis B virus (HBV) replication[1].

HY-B0579S

Cyclosporin A-d4
Cyclosporin A-d₄ is the deuterium labeled Cyclosporin A. Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of calcineurin with an IC50 of 5 nM. Cyclosporin A also inhibits CD11a/CD18 ad

HY-N5034S

Phosphorylethanolamine-d4
Phosphorylethanolamine-d₄ (Monoaminoethyl phosphate-d₄; NSC 254167-d₄) is a deuterium labeled Phosphorylethanolamine (HY-N5034). Phosphorylethanolamine is an endogenous metabolite.

HY-16582AS

Sonidegib-d4
Sonidegib-d4 is a isotope of Sonidegib. Sonidegib is a potent and selective Smo antagonist with IC₅₀ of 1.3 nM and 2.5 nM for mouse and human Smo in binding assay, respectively .

HY-10581AS1

Gatifloxacin-d4 hydrochloride
Gatifloxacin-d₄ (AM-1155-d₄; BMS-206584-d₄; PD135432-d₄) hydrochloride is deuterium-labeled Gatifloxacin (hydrochloride) (HY-10581A) .

HY-W700069

Gatifloxacin-d4
Gatifloxacin-d4 is the deuterium labeled Gatifloxacin .

HY-78004S1

1,2-Diphenylethane-d4
1,2-Diphenylethane-d4 (Dibenzil-d4; s-Diphenylethane-d4; Bibenzyl-d4) is the deuterium labeled Bibenzyl (HY-78004) .

HY-17422S1

Acyclovir-d4

Acyclovir-d₄ is the deuterium labeled Acyclovir. Acyclovir (Aciclovir) is a guanosine analogue and an orally active antiviral agent. Acyclovir inhibits HSV-1 (IC50 of 0.85 μM), HSV-2 (IC50 of 0.86 μM) and varicella-zoster virus. Acyclovir can be phosphorylated by viral thymidine kinase (TK), and Acyclovir triphosphate interferes with viral DNA polymerization through competitive inhibition with guanosine triphosphate and obligatory chain termination[1][2][3]. Acyclovir prevents bacterial infections during induction therapy for acute leukaemia[4].

HY-B0548AS1

Hydroxyzine-d4' dihydrochloride
Hydroxyzine-d₄ (dihydrochloride) is the deuterium labeled Hydroxyzine dihydrochloride. Hydroxyzine dihydrochloride, a benzodiazepine antihistamine agent, acts as a orally active histamine H1-receptor and serotonin antagonist. Hydroxyzine dihydrochloride has anxiolytic effect and can be used forthe research of generalised anxiety disorder[1][2].

HY-B0035S

Sulfamethazine-d4
Sulfamethazine-d₄ is a deuterium labeled Sulfamethazine (Sulfadimidine). Sulfamethazine is an antimicrobial that is widely used to treat and prevent various animal diseases (such as gastrointestinal and respiratory tract infections)[1][2].

HY-B1217S

Bronopol-d4
Bronopol-d₄ is deuterium labeled Bronopol.

HY-W014839S1

Cyclamic acid-d4 sodium
Cyclamic acid-d4 (sodium) is the deuterium labeled Cyclamic acid (sodium) .

HY-15455S

Roflumilast-d4
Roflumilast-d₄ is the deuterium labeled Roflumilast. Roflumilast is a selective PDE4 inhibitor with IC50s of 0.7, 0.9, 0.7, and 0.2 nM for PDE4A1, PDEA4, PDEB1, and PDEB2, respectively, without affecting PDE1, PDE2, PDE3 or PDE5 isoenzymes from various cells[1][2].

HY-B1431S

Butylparaben-d4
Butylparaben-d₄ is the deuterium labeled Butylparaben. Butylparaben is an organic compound, has proven to be a highly successful antimicrobial preservative in cosmetics, also used in medication suspensions, and as a flavoring additive in food.

HY-N0570S

Hydroxytyrosol-d4
Hydroxytyrosol-d₄ is the deuterium labeled Hydroxytyrosol. Hydroxytyrosol (DOPET) is a phenolic compound drawn from the olive tree and its leaves with anti-oxidant, anti-atherogenic, anti-thrombotic, antimicrobial, anti-inflammatory and anti-tumour effects[1][2].

HY-B1290S

2-Phenylethanol-d4

2-Phenylethanol-d₄ is the deuterium labeled 2-Phenylethanol[1]. 2-Phenylethanol (Phenethyl alcohol), extracted from rose, carnation, hyacinth, Aleppo pine, orange blossom and other organisms, is a colourless liquid. It has a pleasant floral odor and also an autoantibiotic produced by the fungus Candida albicans[2]. It is used as an additive in cigarettes and also used as a preservative in soaps due to its stability in basic conditions.

HY-Y1630S

NSC 10281-d4
NSC 10281-d₄ is the deuterium labeled NSC 10281[1].

HY-157075S

(Z)-Rilpivirine-d4
(Z)-Rilpivirine-d₄ (R278474-d₄; TMC278-d₄; DB08864-d₄) is deuterium-labeled (Z)-Rilpivirine .

HY-B0217S

Nitazoxanide-d4
Nitazoxanide-d₄ is the deuterium labeled Nitazoxanide, which is an antiprotozoal agent.

HY-N1150S1

Thymidine-d4
Thymidine-d₄ is the deuterium labeled Thymidine. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication[1][2][3].

HY-14744S

Levamlodipine-d4
Levamlodipine-d₄ is the deuterium labeled Levamlodipine. Levamlodipine ((S)-Amlodipine) is a powerful dihydropyridine calcium channel blocker, possessing vasodilation properties and used in the treatment of hypertension and angina[1].

HY-17043S

Loratadine-d4
Loratadine-d₄ is the deuterium labeled Loratadine. Loratadine (SCH-29851) is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM. Loratadine has anti-dengue-virus (DENV) activity. Loratadine can inhibit immunologic release of inflammatory mediators.

HY-118901S

Opipramol-d4
Opipramol-d₄ is the deuterium labeled Opipramol[1].

HY-B1826S2

Adefovir-d4
Adefovir-d₄ is the deuterium labeled Adefovir. Adefovir (GS-0393) is an adenosine monophosphate analog antiviral agent that after intracellular conversion to Adefovir diphosphate inhibits HBV DNA polymerase. Adefovir has an IC50 of 0.7 μM against HBV in the HepG2.2.15 cell line. Adefovir has good antiviral activity against several viruses, including HBV and herpesviruses[1][2][3].

HY-B0105S1

Ketoconazole-d4
Ketoconazole-d₄ is the deuterium labeled Ketoconazole. Ketoconazole (R-41400) is an imidazole anti-fungal agent, a CYP3A4 and CYP24A1 inhibitor.

HY-B0272S2

Rifampicin-d4
Rifampicin-d₄ is the deuterium labeled Rifampicin. Rifampicin is a potent and broad spectrum antibiotic against bacterial pathogens. Rifampicin has anti-influenza virus activities.

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks