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ADB-5'Br-BUTINACA-d<sub>9</sub>(CRM)

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Click Chemistry:	Azide (2) Alkynes (14)
Oligonucleotides:	Pre-designed siRNA Sets (1) siRNAs (1)

3193

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Recombinant Proteins

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Isotope-Labeled Compounds

Antibodies

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Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W759873S

ADB-5'Br-BUTINACA-d9 (CRM)	Isotope-Labeled Compounds	Others
ADB-5'Br-BUTINACA-d₉ (CRM) is deuterium labeled Adb-5'br-binaca .

HY-RS13999

SUB1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SUB1 Human Pre-designed siRNA Set A contains three designed siRNAs for SUB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SUB1 Human Pre-designed siRNA Set A SUB1 Human Pre-designed siRNA Set A

HY-146227

DNA topoisomerase II inhibitor 1	Topoisomerase Apoptosis	Cancer
DNA topoisomerase II inhibitor 1 (compound 8ed) is a potent DNA topoisomerase II inhibitor. DNA topoisomerase II inhibitor 1 shows anti-proliferative activity. DNA topoisomerase II inhibitor 1 induces apoptosis and cell cycle arrest at sub G1 phase .

HY-158747

*CBDPA (CRM)* Cannabidiphorolic acid	Others	Others
CBDPA (CRM) is a precursor to CBDP, a synthetic plant cannabinoid. CBDPA (CRM) is a standard substance .

HY-170014S

*2-Hydroxyethylflurazepam-d4 (CRM)*	Isotope-Labeled Compounds	Others
2-Hydroxyethylflurazepam-d₄ (CRM) is deuterium labeled 2-Hydroxyethylflurazepam (CRM) .

HY-155972A

CRM1-IN-2	CRM1 Apoptosis	Cancer
CRM1-IN-2 (Compound KL2) is a noncovalent *CRM1* inhibitor. CRM1-IN-2 localizes CRM1 in the nuclear periphery, depletes nuclear CRM1, and inhibits CRM1-mediated nuclear export. CRM1-IN-2 inhibits growth of colorectal cancer cells, and induces apoptosis .

HY-155972

CRM1-IN-1	CRM1	Cancer
CRM1-IN-1 (Compound KL1) is a noncovalent *CRM1* inhibitor. CRM1-IN-1 induces nuclear CRM1 degradation (IC₅₀: 0.27 μM). CRM1-IN-1 inhibits CRM1-mediated nuclear export and cell proliferation, and triggers apoptosis in colorectal cancer cells .

HY-157412

CRM1-IN-3	CRM1	Cancer
CRM1-IN-3 (B28) is a noncovalent CRM1 inhibitor. CRM1-IN-3 can be used for the research of protein localization and tumor .

HY-146384

CRM1 degrader 1	CRM1	Cancer
CRM1 degrader 1 (1l) is a low toxic chromosome region maintenance 1 (CRM1) degrader. CRM1 is the sole nuclear exporter of several tumor suppressor, a growth regulatory protein as an attractive cancer agent target. CRM1 degrader 1 induces the apoptosis in gastric carcinoma and selectively inhibits proliferation of gastric cancer .

HY-10844S1

Pretomanid-d5 PA-824-d<sub>5sub>; (S)-PA 824-d<sub>5sub>	Antibiotic Bacterial Isotope-Labeled Compounds	Infection Cancer
Pretomanid-d₅ is deuterated labeled Pretomanid (HY-10844). Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 μg/mL.

HY-P10215

Ac-{Cpg}-Thr-Ala-{Ala(CO)}-Asp-{Cpg}-NH2	Parasite	Infection
Ac-{Cpg}-Thr-Ala-{Ala(CO)}-Asp-{Cpg}-NH2 (compound 40) is a potent **Plasmodium subtilisin-like protease 1 (SUB1)** inhibitor. SUB1-IN-1 shows IC₅₀ values of 12 nM and 10 nM against P. vivax and P. falciparum SUB1 (Pv- and PfSUB1), respectively .

HY-Y0484S

1-Indanamine-d9 hydrochloride 1-Aminoindan-d<sub>9sub> hydrochloride; 1-Aminoindane-d<sub>9sub> hydrochloride; NSC 186227-d<sub>9sub> hydrochloride; 1-Aminoindane-d<sub>9sub> hydrochloride	Isotope-Labeled Compounds	Others
1-Indanamine-d₉ (1-Aminoindan-d₉; 1-Aminoindane-d₉; NSC 186227-d₉; 1-Aminoindane-d₉) hydrochloride is deuterium-labeled 1-Indanamine hydrochloride (HY-Y0484) .

HY-17020S

Miglustat-d9 N-Butyldeoxynojirimycin-d<sub>9sub>; NB-DNJ-d<sub>9sub>; OGT 918-d<sub>9sub>	Isotope-Labeled Compounds Glucosylceramide Synthase (GCS)	Neurological Disease
Miglustat-d9 is the deuterium labeled Miglustat. Miglustat (N-Butyldeoxynojirimycin) is an inhibitor of glucosylceramide synthase, primarily to treat Type I Gaucher disease (GD1) .

HY-110363

Miglustat-d9 hydrochloride N-Butyldeoxynojirimycin-d<sub>9sub> hydrochloride; NB-DNJ-d<sub>9sub> hydrochloride; OGT 918-d<sub>9sub> hydrochloride	Isotope-Labeled Compounds Glucosylceramide Synthase (GCS)	Neurological Disease
Miglustat-d₉ (hydrochloride) is the deuterium labeled Miglustat (hydrochloride). Miglustat hydrochloride is an inhibitor of glucosylceramide synthase, primarily to treat Type I Gaucher disease (GD1)[1][2].

HY-B1260S3

Cetrimonium-d9(bromide) CTAB-d<sub>9sub>; Cetyltrimethylammonium-d<sub>9sub> Bromide; Hexadecyltrimethylammonium-d<sub>9sub> Bromide	Isotope-Labeled Compounds	Others
Cetrimonium-d₉ (bromide) is the deuterium labeled Cetrimonium bromide[1]. Cetrimonium bromide (CTAB) is an amine based cationic quaternary surfactant, is one of the components of the topical antiseptic Cetrimide.

HY-B1290S1

2-Phenylethanol-d9 Phenylethyl alcohol-d<sub>9sub>; Phenethyl alcohol-d<sub>9sub>; Benzyl carbinol-d<sub>9sub>	Bacterial Virus Protease Antibiotic	Infection
2-Phenylethanol-d₉ is the deuterium labeled 2-Phenylethanol[1]. 2-Phenylethanol (Phenethyl alcohol), extracted from rose, carnation, hyacinth, Aleppo pine, orange blossom and other organisms, is a colourless liquid. It has a pleasant floral odor and also an autoantibiotic produced by the fungus Candida albicans[2]. It is used as an additive in cigarettes and also used as a preservative in soaps due to its stability in basic conditions.

HY-B1431S2

Butylparaben-d9 Butyl parahydroxybenzoate-d<sub>9sub>; Butyl paraben-d<sub>9sub>; Butyl 4-hydroxybenzoate-d<sub>9sub>	Isotope-Labeled Compounds	Infection
Butylparaben-d₉ (Butyl parahydroxybenzoate-d₉; Butyl paraben-d₉) is a deuterium labeled Butylparaben (HY-B1431).

HY-116790BS

(±)-Penbutolol-d9 (Rac)-Penbutolol-d<sub>9sub>; (±)-Isopenbutolol-d<sub>9sub>	5-HT Receptor Adrenergic Receptor Isotope-Labeled Compounds	Others
(±)-Penbutolol-d₉ is the deuterium labeled (±)-Penbutolol[1].

HY-17501S

Bambuterol-d9 hydrochloride (±)-Bambuterol-d<sub>9sub> hydrochloride; KWD-2183-d<sub>9sub> hydrochloride	Adrenergic Receptor	Endocrinology
Bambuterol-d₉ (hydrochloride) is the deuterium labeled Bambuterol. Bambuterol ((±)-Bambuterol) hydrochloride is a long acting beta-adrenoceptor agonist (LABA) used in the treatment of asthma; it also is a prodrug of terbutaline.

HY-B1037S2

Salbutamol-d9 Albuterol-d<sub>9sub>; AH-3365-d<sub>9sub>	Isotope-Labeled Compounds Adrenergic Receptor	Neurological Disease Endocrinology
Salbutamol-d₉ is the deuterium labeled Salbutamol. Salbutamol is a short-acting β2-adrenergic receptor agonist used for the relief of bronchospasm in conditions such as asthma and chronic obstructive pulmonary disease (COPD).

HY-B0269S

Rifapentine-d9 DL 473-d<sub>9sub>; Cyclopentylrifampicin-d<sub>9sub>	Bacterial Antibiotic	Infection
Rifapentine-d₉ is the deuterium labeled Rifapentine. Rifapentine (DL 473) is an antibiotic compound used in the treatment of tuberculosis.

HY-B1037S3

Salbutamol-d9 acetate Albuterol-d<sub>9sub> acetate; AH-3365-d<sub>9sub> acetate	Adrenergic Receptor	Endocrinology
Salbutamol-d₉ (acetate) is the deuterium labeled Salbutamol[1]. Salbutamol is a short-acting β2-adrenergic receptor agonist used for the relief of bronchospasm in conditions such as asthma and chronic obstructive pulmonary disease (COPD).

HY-14865S

Omadacycline-d9 PTK 0796-d<sub>9sub>; Amadacycline-d<sub>9sub>	Bacterial Isotope-Labeled Compounds	Others
Omadacycline-d9 (PTK 0796-d9; Amadacycline-d9) is the deuterium labeled Omadacycline (HY-14865) that can be used as the internal standard for the analysis of Omadacycline .

HY-B0739AS

Citicoline-d9 sodium Cytidine diphosphate-choline-d<sub>9sub> sodium; CDP-Choline-d<sub>9sub>(sodium); Cytidine 5'-diphosphocholine-d<sub>9sub> sodium	Endogenous Metabolite Apoptosis	Neurological Disease
Citicoline-d₉ (sodium) is the deuterium labeled Citicoline sodium. Citicoline sodium salt is an intermediate in the synthesis of phosphatidylcholine which is a component of cell membranes and also exerts neuroprotective effects.

HY-15459S1

Cabazitaxel-d9 XRP6258-d<sub>9sub>; RPR-116258A-d<sub>9sub>; taxoid XRP6258-d<sub>9sub>	Isotope-Labeled Compounds Microtubule/Tubulin Autophagy	Cancer
Cabazitaxel-d₉ is deuterium labeled Cabazitaxel. Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity.

HY-120546S

Ulixacaltamide-d9 hydrochloride Z944-d<sub>9sub> hydrochloride; PRAX-944-d<sub>9sub> hydrochloride	Calcium Channel Isotope-Labeled Compounds	Others
Ulixacaltamide-d₉ (hydrochloride) salt is the deuterium labeled Ulixacaltamide hydrochloride[1].

HY-10237S

Boceprevir-d9 EBP 520-d<sub>9sub>; SCH 503034-d<sub>9sub>	Isotope-Labeled Compounds HCV Protease HCV SARS-CoV	Infection
Boceprevir-d₉ is the deuterium labeled Boceprevir. Boceprevir (EBP 520) is a potent, highly selective, orally bioavailable HCV NS3 protease inhibitor with a Ki of 14 nM in both enzyme assay and an EC90 of 350 nM in cell-based replicon assay[1][2][3][4][5]. Boceprevir inhibits SARS-CoV-2 3CLpro activity[6].

HY-113270AS

Actinine-d9 chloride γ-Butyrobetaine-d<sub>9sub> hydrochloride; Deoxycarnitine-d<sub>9sub> hydrochloride	Endogenous Metabolite	Cardiovascular Disease Metabolic Disease
Actinine-d₉ chloride is the deuterium labeled Actinine chloride. Actinine chloride is angiopathic substance produced as an intermediary metabolite by gut microbiota that feed on carnitine in dietary red meat[1][2].

HY-B2246S

L-Carnitine-d9 chloride (R)-Carnitine-d<sub>9sub> chloride; Levocarnitine-d<sub>9sub> chloride	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
L-Carnitine-d₉ (chloride)e is the deuterium labeled L-Carnitine chloride. L-Carnitine chloride, a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine chloride functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine chloride is an antioxidant. L-Carnitine chloride can ameliorate metabolic imbalances in many inborn errors of metabolism[1][2][3].

HY-17369BS

Tirofiban-d9 L700462-d<sub>9sub>; MK383-d<sub>9sub>	Isotope-Labeled Compounds Integrin	Cardiovascular Disease
Tirofiban-d₉ is deuterium labeled Tirofiban.

HY-B0228S14

Adenosine-d9 Adenine riboside-d<sub>9sub>; D-Adenosine-d<sub>9sub>	Isotope-Labeled Compounds	Others
Adenosine-d₉ is the deuterium labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physio .

HY-Y0453S

4-Carboethoxypiperidine-d9 Ethyl isonipecotate-d<sub>9sub>; NSC 93792-d<sub>9sub>; Piperidin-4-carboxylic acid ethyl ester-d<sub>9sub>	Isotope-Labeled Compounds	Others
4-Carboethoxypiperidine-d₉ is the deuterium labeled 4-Carboethoxypiperidine[1].

HY-N1446S5

Oleic acid-d9 9-cis-Octadecenoic acid-d<sub>9sub>; 9Z-Octadecenoic acid-d<sub>9sub>	Apoptosis Na+/K+ ATPase Endogenous Metabolite	Metabolic Disease Cancer
Oleic acid-d₉ is deuterium labeled Oleic acid (HY-N1446). Oleic acid is an abundant monounsaturated fatty acid. Oleic acid is a Na+/K+ ATPase activato .

HY-14660S

Dabrafenib-d9 GSK2118436A-d<sub>9sub>; GSK2118436-d<sub>9sub>	Isotope-Labeled Compounds Raf	Cancer
Dabrafenib-d₉ is the deuterium labeled Dabrafenib. Dabrafenib (GSK2118436A) is an ATP-competitive inhibitor of Raf with IC50s of 5 nM and 0.6 nM for C-Raf and B-RafV600E, respectively[4].

HY-101952S1

Prostaglandin E2-d9 PGE2-d<sub>9sub>; Dinoprostone-d<sub>9sub>	Isotope-Labeled Compounds Prostaglandin Receptor Endogenous Metabolite	Cardiovascular Disease Endocrinology
Prostaglandin E2-d₉ is the deuterium labeled Prostaglandin E2. Prostaglandin E2 (PGE2) is a hormone-like substance that participate in a wide range of body functions such as the contraction and relaxation of smooth muscle, the dilation and constriction of blood vessels, control of blood pressure, and modulation of inflammation[1][2].

HY-B0131S2

Prostaglandin E1-d9 Alprostadil-d<sub>9sub>; PGE1-d<sub>9sub>	Isotope-Labeled Compounds Prostaglandin Receptor Endogenous Metabolite	Cardiovascular Disease Endocrinology
Prostaglandin E1-d₉ is deuterium labeled Prostaglandin E1.Prostaglandin E1 is a prostanoid receptor ligand, with Kis of 1.1 nM, 2.1 nM, 10 nM, 33 nM and 36 nM for mouse EP3, EP4, EP2, IP and EP1, respectively. Prostaglandin E1 induces vasodilation and inh

HY-W744643

Butylphthalide-d9 3-n-Butylphthalide-d<sub>9sub>; 3-Butylphthalide-d<sub>9sub>	Isotope-Labeled Compounds Others	Neurological Disease
Butylphthalide-d₉ (3-n-Butylphthalide-d₉) is deuterium labeled Butylphthalide. Butylphthalide (3-n-Butylphthalide) is an active molecule against cerebral ischemia. It was originally isolated from celery species and has been shown to be effective in stroke animal models .

HY-17552S

sn-Glycero-3-phosphocholine-d9 Choline Alfoscerate-d<sub>9sub>; Alpha-GPC-d<sub>9sub>; L-α-GPC-d<sub>9sub>	Isotope-Labeled Compounds Cholinesterase (ChE) Endogenous Metabolite	Neurological Disease
sn-Glycero-3-phosphocholine-d₉ is the deuterium labeled sn-Glycero-3-phosphocholine. sn-Glycero-3-phosphocholine (Choline Alfoscerate) is a precursor in the biosynthesis of brain phospholipids and increases the bioavailability of choline in nervous tissue. sn-Glycero-3-phosphocholine (Choline Alfoscerate) has significant effects on cognitive function with a good safety profile and tolerability, and is effective in the treatment of Alzheimer's disease and dementia[1][2].

HY-Y1088S2

Hydrocinnamic acid-d9 3-Phenylpropionic acid-d<sub>9sub>; 3-Phenylpropanoic acid-d<sub>9sub>; 3-Phenyl-n-propionic acid-d<sub>9sub>	Endogenous Metabolite	Others
Hydrocinnamic acid-d₉ is the deuterium labeled Hydrocinnamic acid[1]. Hydrocinnamic acid is the major rhizospheric compound with known growth regulatory activitie[2]s.

HY-125833

Alpha-Naphthoflavone 5+ Cited Publications	Cytochrome P450 Aryl Hydrocarbon Receptor Apoptosis	Cancer
Alpha-Naphthoflavone is an orally active flavonoid that is a potent, competitive inhibitor of aromatase< b>aromatase. < b > IC < sub > 50 < / sub > < / b > and < b > K < sub > I < / sub > < / b > value were 0.5 and 0.2 microns. Alpha-Naphthoflavone can inhibit cell proliferation and induce apoptosis .

HY-N0111S2

Coenzyme Q10-d9 CoQ10-d<sub>9sub>; Ubiquinone-10-d<sub>9sub>	Isotope-Labeled Compounds Endogenous Metabolite Reactive Oxygen Species Ferroptosis	Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Coenzyme Q10-d₉ is the deuterium labeled Coenzyme Q10. Coenzyme Q10 is an essential cofactor of the electron transport chain and a potent antioxidant agent.

HY-B0896S2

Triacetin-d9 Glyceryl triacetate-d<sub>9sub>; 1,2,3-Triacetoxypropane-d<sub>9sub>	Fungal Endogenous Metabolite	Others
Glyceryl Triacetate-d₉ is the deuterium labeled Triacetin[1]. Triacetin is an artificial chemical compound, is the triester of glycerol and acetic acid, and is the second simplest fat after triformin.

HY-Y0012S1

4-Butylaniline-d9 (4-Butylphenyl)amine-d<sub>9sub>; 4-Butylaniline-d<sub>9sub>	Isotope-Labeled Compounds	Others
4-Butylaniline-d₉ is the deuterium labeled 4-Butylaniline[1].

HY-W062703S

(Rac)-Ruxolitinib-d9 (Rac)-INCB18424-d<sub>9sub>; Ruxotinib racemate-d<sub>9sub>	Isotope-Labeled Compounds JAK	Cancer
(Rac)-Ruxolitinib D9 ((Rac)-INCB18424 D9) is the deuterium labeled (Rac)-Ruxolitinib. (Rac)-Ruxolitinib is a JAK2 inhibitor .

HY-12956S1

Dinoprost-d9 Prostaglandin F2a-d<sub>9sub>; PGF2α-d<sub>9sub>	Prostaglandin Receptor Endogenous Metabolite Autophagy Apoptosis	Endocrinology
Dinoprost-d₉ is the deuterium labeled Dinoprost. Dinoprost (Prostaglandin F2α) is an orally active, potent prostaglandin F (PGF) receptor (FP receptor) agonist. Dinoprost is a luteolytic hormone produced locally in the endometrial luminal epithelium and corpus luteum (CL). Dinoprost plays a key role in the onset and progression of labour[1][2].

HY-Y0017S

L-Norleucine-d9 (S)-2-Aminohexanoic acid-d<sub>9sub>; (S)-Norleucine-d<sub>9sub>	Isotope-Labeled Compounds Influenza Virus Endogenous Metabolite	Infection Cancer
L-Norleucine-d₉ is the deuterium labeled L-Norleucine. L-Norleucine ((S)-2-Aminohexanoic acid) is an isomer of leucine, specifically affects protein synthesis in skeletal muscle, and has antivirus activity.

HY-17380S

(S)-Timolol-d9 maleate (S)-L-714,465-d<sub>9sub> maleate; MK 950-d<sub>9sub>	Isotope-Labeled Compounds Adrenergic Receptor	Cardiovascular Disease Neurological Disease
(S)-Timolol-d₉ (maleate) is deuterium labeled (S)-Timolol (Maleate). (S)-Timolol Maleate (L-714,465 Maleate) is a non-cardioselective hydrophilic β-adrenoceptor blocker. (S)-Timolol Maleate is widely used as standard medication for intraocular pressure (glaucoma) by preventing the production of aqueous humor. (S)-Timolol Maleate can be used for hypertension, angina pectoris and myocardial infarction[1][2][3].

HY-17496S

(R)-Timolol-d9 maleate L-714,465-d<sub>9sub> maleate; (R)-MK 950-d<sub>9sub>	Isotope-Labeled Compounds	Others
(R)-Timolol-d₉ (maleate) is deuterium labeled (R)-Timolol (maleate).

HY-113218S

Acetyl-L-carnitine-d9 O-Acetyl-L-carnitine-d<sub>9sub>; ALCAR-d<sub>9sub>	Isotope-Labeled Compounds Others	Others
Acetyl-L-carnitine-d₉ (O-Acetyl-L-carnitine-d₉) is deuterium labeled Acetyl-L-carnitine. Acetyl-L-carnitine (O-Acetyl-L-carnitine) is a compound involved in human metabolic research. It has relevant applications in predicting metabolite biomarker changes using the Recon 2 metabolic reconstruction model and integrating and analyzing multiple data types, but its specific activity mechanism is not described in detail based on the existing information .

HY-W783639S

Bzo-poxizid-d9 5C-MDA-19-d<sub>9sub>, Petyl MDA-19-d<sub>9sub>	Isotope-Labeled Compounds Cannabinoid Receptor	Neurological Disease
Bzo-poxizid-d₉ (5C-MDA-19-d₉, Petyl MDA-19-d₉) is deuterium labeled Bzo-poxizid. Bzo-poxizid is a synthetic cannabinoid that is a psychoactive substance .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-125833

Alpha-Naphthoflavone 5+ Cited Publications	Flavonoids Flavones Source classification Indigofera heterantha Wall. ex Brand. Plants Compositae Disease Research Fields Cancer	Cytochrome P450 Aryl Hydrocarbon Receptor Apoptosis
Alpha-Naphthoflavone is an orally active flavonoid that is a potent, competitive inhibitor of aromatase< b>aromatase. < b > IC < sub > 50 < / sub > < / b > and < b > K < sub > I < / sub > < / b > value were 0.5 and 0.2 microns. Alpha-Naphthoflavone can inhibit cell proliferation and induce apoptosis .

HY-W011474

Geranylgeraniol	Structural Classification Natural Products Microorganisms	NF-κB
Geranylgeraniol is an orally acitve vitamin K₂ sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model .

HY-P2274

Argifin	Infection Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields	Parasite
Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms, with IC₅₀s of 0.025 μM, 6.4 μM , 1.1 μM and 4.5 μM for SmChiA (Serratia marcescens chitinaese A), SmChiB, Aspergillus fumigatus chitinase B1 and human chitotriosidase, respectively .

HY-N0662

Amentoflavone Maximum Cited Publications 9 Publications Verification Didemethyl-ginkgetin	Structural Classification Flavonoids Classification of Application Fields Source classification Phenols Polyphenols Selaginellaceae Plants Biflavones Selaginella tamariscina (P. Beauv.) Spring Disease Research Fields Cancer	Reactive Oxygen Species Apoptosis Bacterial Fungal RSV GABA Receptor
Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active GABA(A) negative modulator. Amentoflavone also shows anti-inflammatory, antioxidative, anti-viral, anti-tumor, anti-radiation, anti-fungal, antibacterial activity. Amentoflavone induces apoptosis and cell cycle arrest at sub-G1 phase .

HY-N6795

Leptomycin A	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Disease Research Fields Other Antibiotics	CRM1 HIV Antibiotic
Leptomycin A, a Streptomyces metabolite, is an inhibitor of CRM1 (exportin 1) that blocks CRM1 interaction with nuclear export signals, preventing the nuclear export of a broad range of proteins. Leptomycin A suppresses HIV-1 replication. Less potent than Leptomycin B .

HY-B0504S

Creatinine-d3 3 Publications Verification NSC13123-d<sub>3sub>	Classification of Application Fields Metabolic Disease Disease Research Fields	Endogenous Metabolite
Creatinine-d₃ is a deuterium labeled Creatinine. Creatinine is a break-down product of creatine phosphate in muscle[1].

HY-N11799

Neochilenin 3-O-Methylquercetin 4′-O-glucoside	Structural Classification Flavonoids Source classification Plants Compositae Other Flavonoids	Others
Neochilenin (3-O-Methylquercetin 4 '-O-glucoside) is a glycoside of 3-O-methylquercetin, which can be isolated from the sub-family Cereoideae (Cactaceae). .

HY-N10192

Aculene D	Infection Microorganisms Classification of Application Fields Terpenoids Sesquiterpenes Source classification Disease Research Fields	Endogenous Metabolite Bacterial
Aculene D, a fungal metabolite, shows quorum sensing (QS) inhibitory activity against Chromobacterium violaceum CV026, and could significantly reduce violacein production in N-hexanoyl-l-homoserine lactone (C6-HSL) induced C. violaceum CV026 cultures at sub-inhibitory concentrations .

HY-W011474R

Geranylgeraniol (Standard)	Structural Classification Natural Products Microorganisms	NF-κB
Geranylgeraniol (Standard) is the analytical standard of Geranylgeraniol. This product is intended for research and analytical applications. Geranylgeraniol is an orally acitve vitamin K2 sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model [4].

HY-N0662R

Amentoflavone (Standard)	Structural Classification Flavonoids Source classification Phenols Polyphenols Selaginellaceae Plants Biflavones Selaginella tamariscina (P. Beauv.) Spring	Reactive Oxygen Species Apoptosis Bacterial Fungal RSV GABA Receptor
Amentoflavone (Standard) is the analytical standard of Amentoflavone. This product is intended for research and analytical applications. Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active GABA(A) negative modulator. Amentoflavone also shows anti-inflammatory, antioxidative, anti-viral, anti-tumor, anti-radiation, anti-fungal, antibacterial activity. Amentoflavone induces apoptosis and cell cycle arrest at sub-G1 phase .

HY-N10264

Avrainvillamide (+)-Avrainvillamide; CJ-17,665	Infection Alkaloids Structural Classification Microorganisms Pyrrole Alkaloids Classification of Application Fields Source classification Disease Research Fields Indole Alkaloids	Antibiotic
Avrainvillamide ((+)-Avrainvillamide) is a naturally occurring alkaloid with antiproliferative effects, binds to the nuclear chaperone nucleophosmin, a proposed oncogenic protein that is overexpressed in many different human tumors. Avrainvillamide affects cell biology both by directly binding NPM1 and Crm1 as well as by inhibiting the association of these proteins with certain native cellular partners. Avrainvillamide, an antibiotic, inhibits growth of multi-agent resistant Staphylococcus aureus, Streptococcus pyogenes, and Enterococcus faecalis, with MICs of 12.5, 12.5 and 25 μg/ml, respectively .

Cat. No.	Product Name	Chemical Structure

HY-W759873S

ADB-5'Br-BUTINACA-d9 (CRM)
ADB-5'Br-BUTINACA-d₉ (CRM) is deuterium labeled Adb-5'br-binaca .

HY-170014S

*2-Hydroxyethylflurazepam-d4 (CRM)*
2-Hydroxyethylflurazepam-d₄ (CRM) is deuterium labeled 2-Hydroxyethylflurazepam (CRM) .

HY-10844S1

Pretomanid-d5
Pretomanid-d₅ is deuterated labeled Pretomanid (HY-10844). Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 μg/mL.

HY-Y0484S

1-Indanamine-d9 hydrochloride
1-Indanamine-d₉ (1-Aminoindan-d₉; 1-Aminoindane-d₉; NSC 186227-d₉; 1-Aminoindane-d₉) hydrochloride is deuterium-labeled 1-Indanamine hydrochloride (HY-Y0484) .

HY-17020S

Miglustat-d9
Miglustat-d9 is the deuterium labeled Miglustat. Miglustat (N-Butyldeoxynojirimycin) is an inhibitor of glucosylceramide synthase, primarily to treat Type I Gaucher disease (GD1) .

HY-110363

Miglustat-d9 hydrochloride
Miglustat-d₉ (hydrochloride) is the deuterium labeled Miglustat (hydrochloride). Miglustat hydrochloride is an inhibitor of glucosylceramide synthase, primarily to treat Type I Gaucher disease (GD1)[1][2].

HY-B1260S3

Cetrimonium-d9(bromide)
Cetrimonium-d₉ (bromide) is the deuterium labeled Cetrimonium bromide[1]. Cetrimonium bromide (CTAB) is an amine based cationic quaternary surfactant, is one of the components of the topical antiseptic Cetrimide.

HY-B1290S1

2-Phenylethanol-d9

2-Phenylethanol-d₉ is the deuterium labeled 2-Phenylethanol[1]. 2-Phenylethanol (Phenethyl alcohol), extracted from rose, carnation, hyacinth, Aleppo pine, orange blossom and other organisms, is a colourless liquid. It has a pleasant floral odor and also an autoantibiotic produced by the fungus Candida albicans[2]. It is used as an additive in cigarettes and also used as a preservative in soaps due to its stability in basic conditions.

HY-B1431S2

Butylparaben-d9
Butylparaben-d₉ (Butyl parahydroxybenzoate-d₉; Butyl paraben-d₉) is a deuterium labeled Butylparaben (HY-B1431).

HY-116790BS

(±)-Penbutolol-d9
(±)-Penbutolol-d₉ is the deuterium labeled (±)-Penbutolol[1].

HY-17501S

Bambuterol-d9 hydrochloride
Bambuterol-d₉ (hydrochloride) is the deuterium labeled Bambuterol. Bambuterol ((±)-Bambuterol) hydrochloride is a long acting beta-adrenoceptor agonist (LABA) used in the treatment of asthma; it also is a prodrug of terbutaline.

HY-B1037S2

Salbutamol-d9
Salbutamol-d₉ is the deuterium labeled Salbutamol. Salbutamol is a short-acting β2-adrenergic receptor agonist used for the relief of bronchospasm in conditions such as asthma and chronic obstructive pulmonary disease (COPD).

HY-B0269S

Rifapentine-d9
Rifapentine-d₉ is the deuterium labeled Rifapentine. Rifapentine (DL 473) is an antibiotic compound used in the treatment of tuberculosis.

HY-B1037S3

Salbutamol-d9 acetate
Salbutamol-d₉ (acetate) is the deuterium labeled Salbutamol[1]. Salbutamol is a short-acting β2-adrenergic receptor agonist used for the relief of bronchospasm in conditions such as asthma and chronic obstructive pulmonary disease (COPD).

HY-14865S

Omadacycline-d9
Omadacycline-d9 (PTK 0796-d9; Amadacycline-d9) is the deuterium labeled Omadacycline (HY-14865) that can be used as the internal standard for the analysis of Omadacycline .

HY-B0739AS

Citicoline-d9 sodium
Citicoline-d₉ (sodium) is the deuterium labeled Citicoline sodium. Citicoline sodium salt is an intermediate in the synthesis of phosphatidylcholine which is a component of cell membranes and also exerts neuroprotective effects.

HY-15459S1

Cabazitaxel-d9
Cabazitaxel-d₉ is deuterium labeled Cabazitaxel. Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity.

HY-120546S

Ulixacaltamide-d9 hydrochloride
Ulixacaltamide-d₉ (hydrochloride) salt is the deuterium labeled Ulixacaltamide hydrochloride[1].

HY-10237S

Boceprevir-d9
Boceprevir-d₉ is the deuterium labeled Boceprevir. Boceprevir (EBP 520) is a potent, highly selective, orally bioavailable HCV NS3 protease inhibitor with a Ki of 14 nM in both enzyme assay and an EC90 of 350 nM in cell-based replicon assay[1][2][3][4][5]. Boceprevir inhibits SARS-CoV-2 3CLpro activity[6].

HY-113270AS

Actinine-d9 chloride
Actinine-d₉ chloride is the deuterium labeled Actinine chloride. Actinine chloride is angiopathic substance produced as an intermediary metabolite by gut microbiota that feed on carnitine in dietary red meat[1][2].

HY-B2246S

L-Carnitine-d9 chloride

L-Carnitine-d₉ (chloride)e is the deuterium labeled L-Carnitine chloride. L-Carnitine chloride, a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine chloride functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine chloride is an antioxidant. L-Carnitine chloride can ameliorate metabolic imbalances in many inborn errors of metabolism[1][2][3].

HY-17369BS

Tirofiban-d9
Tirofiban-d₉ is deuterium labeled Tirofiban.

HY-B0228S14

Adenosine-d9
Adenosine-d₉ is the deuterium labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physio .

HY-Y0453S

4-Carboethoxypiperidine-d9
4-Carboethoxypiperidine-d₉ is the deuterium labeled 4-Carboethoxypiperidine[1].

HY-N1446S5

Oleic acid-d9
Oleic acid-d₉ is deuterium labeled Oleic acid (HY-N1446). Oleic acid is an abundant monounsaturated fatty acid. Oleic acid is a Na+/K+ ATPase activato .

HY-14660S

Dabrafenib-d9
Dabrafenib-d₉ is the deuterium labeled Dabrafenib. Dabrafenib (GSK2118436A) is an ATP-competitive inhibitor of Raf with IC50s of 5 nM and 0.6 nM for C-Raf and B-RafV600E, respectively[4].

HY-101952S1

Prostaglandin E2-d9
Prostaglandin E2-d₉ is the deuterium labeled Prostaglandin E2. Prostaglandin E2 (PGE2) is a hormone-like substance that participate in a wide range of body functions such as the contraction and relaxation of smooth muscle, the dilation and constriction of blood vessels, control of blood pressure, and modulation of inflammation[1][2].

HY-B0131S2

Prostaglandin E1-d9
Prostaglandin E1-d₉ is deuterium labeled Prostaglandin E1.Prostaglandin E1 is a prostanoid receptor ligand, with Kis of 1.1 nM, 2.1 nM, 10 nM, 33 nM and 36 nM for mouse EP3, EP4, EP2, IP and EP1, respectively. Prostaglandin E1 induces vasodilation and inh

HY-W744643

Butylphthalide-d9
Butylphthalide-d₉ (3-n-Butylphthalide-d₉) is deuterium labeled Butylphthalide. Butylphthalide (3-n-Butylphthalide) is an active molecule against cerebral ischemia. It was originally isolated from celery species and has been shown to be effective in stroke animal models .

HY-17552S

sn-Glycero-3-phosphocholine-d9

sn-Glycero-3-phosphocholine-d₉ is the deuterium labeled sn-Glycero-3-phosphocholine. sn-Glycero-3-phosphocholine (Choline Alfoscerate) is a precursor in the biosynthesis of brain phospholipids and increases the bioavailability of choline in nervous tissue. sn-Glycero-3-phosphocholine (Choline Alfoscerate) has significant effects on cognitive function with a good safety profile and tolerability, and is effective in the treatment of Alzheimer's disease and dementia[1][2].

HY-Y1088S2

Hydrocinnamic acid-d9
Hydrocinnamic acid-d₉ is the deuterium labeled Hydrocinnamic acid[1]. Hydrocinnamic acid is the major rhizospheric compound with known growth regulatory activitie[2]s.

HY-N0111S2

Coenzyme Q10-d9
Coenzyme Q10-d₉ is the deuterium labeled Coenzyme Q10. Coenzyme Q10 is an essential cofactor of the electron transport chain and a potent antioxidant agent.

HY-B0896S2

Triacetin-d9
Glyceryl Triacetate-d₉ is the deuterium labeled Triacetin[1]. Triacetin is an artificial chemical compound, is the triester of glycerol and acetic acid, and is the second simplest fat after triformin.

HY-Y0012S1

4-Butylaniline-d9
4-Butylaniline-d₉ is the deuterium labeled 4-Butylaniline[1].

HY-W062703S

(Rac)-Ruxolitinib-d9
(Rac)-Ruxolitinib D9 ((Rac)-INCB18424 D9) is the deuterium labeled (Rac)-Ruxolitinib. (Rac)-Ruxolitinib is a JAK2 inhibitor .

HY-12956S1

Dinoprost-d9
Dinoprost-d₉ is the deuterium labeled Dinoprost. Dinoprost (Prostaglandin F2α) is an orally active, potent prostaglandin F (PGF) receptor (FP receptor) agonist. Dinoprost is a luteolytic hormone produced locally in the endometrial luminal epithelium and corpus luteum (CL). Dinoprost plays a key role in the onset and progression of labour[1][2].

HY-Y0017S

L-Norleucine-d9
L-Norleucine-d₉ is the deuterium labeled L-Norleucine. L-Norleucine ((S)-2-Aminohexanoic acid) is an isomer of leucine, specifically affects protein synthesis in skeletal muscle, and has antivirus activity.

HY-17380S

(S)-Timolol-d9 maleate

(S)-Timolol-d₉ (maleate) is deuterium labeled (S)-Timolol (Maleate). (S)-Timolol Maleate (L-714,465 Maleate) is a non-cardioselective hydrophilic β-adrenoceptor blocker. (S)-Timolol Maleate is widely used as standard medication for intraocular pressure (glaucoma) by preventing the production of aqueous humor. (S)-Timolol Maleate can be used for hypertension, angina pectoris and myocardial infarction[1][2][3].

HY-17496S

(R)-Timolol-d9 maleate
(R)-Timolol-d₉ (maleate) is deuterium labeled (R)-Timolol (maleate).

HY-113218S

Acetyl-L-carnitine-d9

Acetyl-L-carnitine-d₉ (O-Acetyl-L-carnitine-d₉) is deuterium labeled Acetyl-L-carnitine. Acetyl-L-carnitine (O-Acetyl-L-carnitine) is a compound involved in human metabolic research. It has relevant applications in predicting metabolite biomarker changes using the Recon 2 metabolic reconstruction model and integrating and analyzing multiple data types, but its specific activity mechanism is not described in detail based on the existing information .

HY-W783639S

Bzo-poxizid-d9
Bzo-poxizid-d₉ (5C-MDA-19-d₉, Petyl MDA-19-d₉) is deuterium labeled Bzo-poxizid. Bzo-poxizid is a synthetic cannabinoid that is a psychoactive substance .

HY-D0184S5

2'-Deoxycytidine-13C9
2'-Deoxycytidine- ¹³C₉ (Deoxycytidine- ¹³C₉; Cytosine deoxyriboside- ¹³C₉; Deoxyribose cytidine- ¹³C₉) is ¹³C-labeled 2'-Deoxycytidine (HY-D0184). 2'-Deoxycytidine, a deoxyribonucleoside, could inhibit biological effects of Bromodeoxyuridine (Brdu).

HY-165648S

PtdIns-(1-palmitoyl-d9, 2-palmitoyl) sodium salt
PtdIns-(1-palmitoyl-d₉, 2-palmitoyl) (DPPI-d₉) sodium salt is deuterium labeled PtdIns-(1-palmitoyl, 2-palmitoyl) (sodium salt) .

HY-B0803S1

Lumefantrine-d9
Lumefantrine-d₉ is the deuterium labeled Lumefantrine. Lumefantrine is an antimalarial drug, used in combination with Artemether. The artemether-lumefantrine (AL) as the first- and second-line anti-malarial drugs.

HY-B0282S1

Acetylcholine-d9 chloride

Acetylcholine-d₉ (chloride) is the deuterium labeled Acetylcholine chloride. Acetylcholine chloride (ACh chloride), a neurotransmitter, is a potent cholinergic agonist. Acetylcholine chloride is a modulator of the activity of dopaminergic (DAergic) neurons through the stimulation of nicotinic acetylcholine receptors (nAChRs)[1][2]. Acetylcholine chloride inhibits p53 mutant peptide aggregation in vitro[5].

HY-131104AS

Brombuterol-d9 hydrochloride
Brombuterol-d₉ (hydrochloride) is a deuterium labeled Brombuterol hydrochloride. Brombuterol hydrochloride is a β-adrenergic receptor agonist[1].

HY-131104S

Brombuterol-d9
Brombuterol-d₉ is a deuterium labeled Brombuterol. Brombuterol is a β-adrenergic receptor agonist[1].

HY-N1318S

Salvigenin-d9
Salvigenin-d₉ is the deuterium labeled Salvigenin. Salvigenin is a natural polyphenolic compound, with neuroprotective effect. Salvigenin has antitumor cytotoxic and immunomodulatory properties[1][2].

HY-B0364AS

Dyclonine-d9 hydrochloride
Dyclonine-d₉ (hydrochloride) is deuterium labeled Dyclonine (hydrochloride). Dyclonine hydrochloride (Dyclocaine hydrochloride) is an effective component of Runhou tablets. Dyclonine hydrochloride has significant bactericidal and fungicidal activity[1][2].

HY-B1319S1

Pramocaine-d9 hydrochloride
Pramocaine-d₉ (hydrochloride) is deuterium labeled Pramocaine (hydrochloride). Pramocaine hydrochloride decreases the permeability of neuronal membranes to sodium ions, blocking both initiation and conduction of nerve impulses.

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