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Ganglioside GM3-d<sub>3</sub>

" in MedChemExpress (MCE) Product Catalog:

2993

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14

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5

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5

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18

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16

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2910

Isotope-Labeled Compounds

3

Antibodies

16

Click Chemistry

1

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Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-114456
    Ganglioside GM3

    		Others Metabolic Disease
    Ganglioside GM3 is a precursor of a-, b-, and c-series gangliosides, interacts with transmembrane receptors such as the epidermal growth factor and insulin receptors, and regulates receptor functions by creating a specialized lipid environment. Ganglioside GM3 is synthesized by GM3 synthase and can be used for the research of hypercholesterolemia .
    Ganglioside GM3
  • HY-157343A
    GD3 Ganglioside sodium

    		Apoptosis Neurological Disease Cancer
    GD3 Ganglioside sodium is a prominent ganglioside of human melanoma. GD3 Ganglioside sodium is an inducer of mitochondrial permeability. GD3 ganglioside directly targets mitochondria in a bcl-2-controlled fashion. GD3 ganglioside is rapidly synthesized from accumulated ceramide after the clustering of death-inducing receptors and triggers apoptosis .
    GD3 Ganglioside sodium
  • HY-152002S
    Ganglioside GM3-d3 ammonium

    		Isotope-Labeled Compounds Others
    Ganglioside GM3-d3 ammonium is a deuterated labeled Ganglioside GM3 ammonium .
    Ganglioside GM3-d3 ammonium
  • HY-114456AS
    Ganglioside GM3-d5 Bovine Milk ammonium salt

    		Isotope-Labeled Compounds Others
    Ganglioside GM3-d5 (Bovine Milk ammonium salt) is deuterium labeled Ganglioside GM3 (Bovine Milk ammonium salt).
    Ganglioside GM3-d5 Bovine Milk ammonium salt
  • HY-N10511
    GM1a Ganglioside oligosaccharide

    		Others Inflammation/Immunology
    GM1a Ganglioside oligosaccharide is a semisynthetic form of ganglioside GM1. Ganglioside GM1 is the natural receptor for cholera toxin and plays an important role not only in general growth regulation but also in the coupling of hormone-induced responses .
    GM1a Ganglioside oligosaccharide
  • HY-157343
    GD3 Ganglioside

    		Apoptosis Neurological Disease Cancer
    GD3 Ganglioside is a prominent ganglioside of human melanoma. GD3 Ganglioside is an inducer of mitochondrial permeability. GD3 ganglioside directly targets mitochondria in a bcl-2-controlled fashion. GD3 ganglioside is rapidly synthesized from accumulated ceramide after the clustering of death-inducing receptors and triggers apoptosis .
    GD3 Ganglioside
  • HY-RS13999
    SUB1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    SUB1 Human Pre-designed siRNA Set A contains three designed siRNAs for SUB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    SUB1 Human Pre-designed siRNA Set A
    SUB1 Human Pre-designed siRNA Set A
  • HY-146227
    DNA topoisomerase II inhibitor 1

    		Topoisomerase Apoptosis Cancer
    DNA topoisomerase II inhibitor 1 (compound 8ed) is a potent DNA topoisomerase II inhibitor. DNA topoisomerase II inhibitor 1 shows anti-proliferative activity. DNA topoisomerase II inhibitor 1 induces apoptosis and cell cycle arrest at sub G1 phase .
    DNA topoisomerase II inhibitor 1
  • HY-N10546
    Ganglioside GM1

    		Others Neurological Disease
    Ganglioside GM1 is a member of the ganglioside family that can be used for neurological disease research. Ganglioside GM1 is a functional tissue receptor for the Cholera Toxin1 .
    Ganglioside GM1
  • HY-10844S1
    Pretomanid-d5

    PA-824-d<sub>5sub>; (S)-PA 824-d<sub>5sub>

    		 Antibiotic Bacterial Isotope-Labeled Compounds Infection Cancer
    Pretomanid-d5 is deuterated labeled Pretomanid (HY-10844). Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 μg/mL.
    Pretomanid-d5
  • HY-148385
    Ganglioside GM2

    		Others Cancer
    Ganglioside GM2 is a human tumor antigen (OFA-I-1). Ganglioside GM2 is the major lysosomal storage compound of Tay-Sachs disease .
    Ganglioside GM2
  • HY-N10546A
    Ganglioside GM1 (bovine) (ammonium)

    		Others Neurological Disease
    Ganglioside GM1 (bovine) ammonium is a member of the ganglioside family that can be used for neurological disease research. Ganglioside GM1 (bovine) ammonium is a functional tissue receptor for the Cholera Toxin1 .
    Ganglioside GM1 (bovine) (ammonium)
  • HY-131139
    Ganglioside GD3 disodium salt

    		Apoptosis Neurological Disease Cancer
    Ganglioside GD3 disodium salt is an acidic glycosphingolipid. Ganglioside GD3 disodium salt inhibits the proliferation of cancer cells, affects the opening of the mitochondrial permeability transition pore (PTPC), induces apoptosis and activates caspase family. Ganglioside GD3 disodium salt can be used in research about cancer and neurodegenerative diseases .
    Ganglioside GD3 disodium salt
  • HY-131139A
    Ganglioside GD3 diammonium

    		Apoptosis Neurological Disease Cancer
    Ganglioside GD3 diammonium is an acidic glycosphingolipid. Ganglioside GD3 diammonium inhibits the proliferation of cancer cells, affects the opening of the mitochondrial permeability transition pore (PTPC), induces apoptosis and activates caspase family. Ganglioside GD3 diammonium can be used in research about cancer and neurodegenerative diseases .
    Ganglioside GD3 diammonium
  • HY-146876S
    C18:0 GM1 Ganglioside-d5 ammonium

    		Isotope-Labeled Compounds Others
    C18:0 GM1 Ganglioside-d5 (ammonium) is deuterium labeled C18:0 GM1 Ganglioside (ammonium).
    C18:0 GM1 Ganglioside-d5 ammonium
  • HY-W714151
    Ganglioside ga1

    Gg4cer; AsialoGanglioside GM1; Asialo GM1, Gangliotetraosylceramide; Asialo Ganglioside GM1a [...]; Ganglio-n-tetraosylceramide; Asialo GM1 Ganglioside; AsialoGanglioside gt1b

    		 Others Metabolic Disease
    Ganglioside ga1 (Gg4cer; Asialoganglioside gm1; Asialo gm1, Gangliotetraosylceramide; Asialo ganglioside gm1a [...]; Ganglio-n-tetraosylceramide; Asialo gm1 ganglioside; Asialoganglioside gt1b) is an ester product.
    Ganglioside ga1
  • HY-W747597
    Ganglioside GD1b Disodium Salt (Bovine Brain)

    DisialoGanglioside GD1b; Ganglioside C1; Ganglioside G2

    		 Endogenous Metabolite Cardiovascular Disease
    Ganglioside GD1b is an acidic glycosphingolipid that contains two sialic acid residues linked to an inner galactose unit. It is a component of plasma membranes where it packs densely with cholesterol to form lipid microdomains that modulate both intra- and intercellular signaling events. The concentration of ganglioside GD1b in human brain increases with age, constituting 7.85% of total sialic acid in the brain of 0- to 10-year-old subjects and 20.29% in 11- to 30-year-old subjects.2 Ganglioside GD1b levels are positively correlated with pilocytic astrocytoma tumor grade, and GD1b has been detected in various other gliomas, including primitive neuroectodermal tumors, glioblastomas, and anaplastic astrocytomas.3 This product contains ganglioside GD1b molecular species with primarily C18:0 fatty acyl chain lengths.
    Ganglioside GD1b Disodium Salt (Bovine Brain)
  • HY-E70043
    Ganglioside sialidase (AuSialidase S)

    Sialidase isoenzyme S; AuSialidase S

    		 Endogenous Metabolite Metabolic Disease
    Ganglioside sialidase (AuSialidase S) is an endogenous metabolite. Ganglioside sialidases have been implicated in neuronal differentiation processes, including neurite outgrowth .
    Ganglioside sialidase (AuSialidase S)
  • HY-E70073
    Ganglioside sialidase (AuSialidase M2)

    Sialidase isoenzyme M2; AuSialidase M2

    		 Others Others
    Ganglioside sialidase (AuSialidase M2) from Arthrobacter ureafaciens. Ganglioside sialidase is a highly specific N-acetylneuraminidase. Ganglioside sialidase can hydrolyze the internal sialic acid of GM1 under optimal condition with sodium cholate .
    Ganglioside sialidase (AuSialidase M2)
  • HY-B1689AS
    Methantheline-d3 bromide

    MTB 51-d<sub>3sub>; Mantheline-d<sub>3sub>; Metantyl-d<sub>3sub>; Metanyl-d<sub>3sub>; Metaxan-d<sub>3sub>; Methanide-d<sub>3sub>

    		 Isotope-Labeled Compounds Others
    Methantheline-d3 (bromide) is the deuterium labeled Methantheline bromide[1].
    Methantheline-d3 bromide
  • HY-W747599
    Ganglioside GQ1b (bovine) (sodium)

    ​TetrasialoGanglioside GQ1b sodium

    		 Others Neurological Disease
    Ganglioside GQ1b (bovine) sodium promotes neurite outgrowth during early neuronal differentiation. Ganglioside GQ1b (bovine) sodium controls the neuronal differentiation process in mESCs .
    Ganglioside GQ1b (bovine) (sodium)
  • HY-W127461
    Ganglioside GM2, Asialo

    Gangliotriosylceramide

    		 Biochemical Assay Reagents Others
    Ganglioside GM2 asialo (asialo-GM2) is a glycosphingolipid containing three monosaccharide residues and one fatty acid of variable chain length, but lacks the sialic acid residue present on ganglioside M2. Asialo-GM2 is found at low or undetectable levels in normal human brains, but it accumulates in the brains of patients with Tay-Sachs disease and Sandhoff disease, which are expressed as lysosomal β- A neurodegenerative disorder characterized by hexosaminidase A and B deficiency. It also binds to various bacteria, including Pseudomonas isolated from cystic fibrosis patients. The Asialo-GM2 mixture contains ganglioside GM2 asialo molecular species with fatty acyl chains of variable length.
    Ganglioside GM2, Asialo
  • HY-113323S
    3-Methoxy-4-hydroxyphenylglycol-d3

    HMPG-d<sub>3sub>; MHPG-d<sub>3sub>; MOPEG-d<sub>3sub>

    		 Endogenous Metabolite Others
    3-Methoxy-4-hydroxyphenylglycol-d3 is the deuterium labeled 3-Methoxy-4-hydroxyphenylglycol.
    3-Methoxy-4-hydroxyphenylglycol-d3
  • HY-17413S
    Zidovudine-d3

    Azidothymidine-d<sub>3sub>; AZT-d<sub>3sub>; ZDV-d<sub>3sub>

    		 Isotope-Labeled Compounds HIV CRISPR/Cas9 Infection
    Zidovudine-d3 is the deuterium labeled Zidovudine. Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection. Zidovudine increases CRISPR/Cas9-mediated editing frequency. Zidovudine-d3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    Zidovudine-d3
  • HY-B1773AS5
    Sodium Propionate-d3

    Mycoban-d<sub>3sub>; Napropion-d<sub>3sub>; Ocuseptine-d<sub>3sub>

    		 Isotope-Labeled Compounds Others
    Sodium Propionate-d3 is the deuterium labeled Sodium Propionate[1].
    Sodium Propionate-d3
  • HY-B0113S
    Omeprazole-d<sub>3sub>

    H 16868-d<sub>3sub>

    		 Proton Pump Bacterial Autophagy Infection Metabolic Disease Cancer
    Omeprazole-d3 is deuterium labeled Omeprazole. Omeprazole, a proton pump inhibitor (PPI), is available for treatment of acid-related gastrointestinal disorders. Omeprazole shows competitive inhibition of CYP2C19 activity with a Ki of 2 to 6 μM[1]. Omeprazole also inhibits growth of Gram-positive and Gram-negative bacteria[2].
    Omeprazole-d<sub>3</sub>
  • HY-125833
    Alpha-Naphthoflavone
    5+ Cited Publications

    		 Cytochrome P450 Aryl Hydrocarbon Receptor Apoptosis Cancer
    Alpha-Naphthoflavone is an orally active flavonoid that is a potent, competitive inhibitor of aromatase< b>aromatase. < b > IC < sub > 50 < / sub > < / b > and < b > K < sub > I < / sub > < / b > value were 0.5 and 0.2 microns. Alpha-Naphthoflavone can inhibit cell proliferation and induce apoptosis [3] .
    Alpha-Naphthoflavone
  • HY-70002S
    Deutenzalutamide

    Enzalutamide-d<sub>3sub>; MDV3100-d<sub>3sub>

    		 Androgen Receptor Autophagy Cancer
    Deutenzalutamide (Enzalutamide-d3) is a developed deuterium labeled Enzalutamide (MDV3100). Enzalutamide is an androgen receptor (AR) antagonist with an IC50 of 36 nM in LNCaP prostate cells .
    Deutenzalutamide
  • HY-B0457AS
    Clomipramine-d3

    Chlorimipramine-d<sub>3sub>; G-34586-d<sub>3sub>; NSC-169865-d<sub>3sub>

    		 Serotonin Transporter Dopamine Receptor Neurological Disease
    Clomipramine-d3 is the deuterium labeled Clomipramine. Clomipramine is a serotonin transporter (SERT), norepinephrine transporter (NET) dopamine transporter (DAT) blocker with Ki of 0.14, 54 and 3 nM, respectively[1][2].
    Clomipramine-d3
  • HY-66005S1
    Acetaminophen-d3

    Paracetamol-d<sub>3sub>; 4-Acetamidophenol-d<sub>3sub>; 4'-Hydroxyacetanilide-d<sub>3sub>

    		 COX Histone Acetyltransferase Endogenous Metabolite Inflammation/Immunology
    Acetaminophen-d3 is the deuterium labeled Acetaminophen. Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM; is a widely used antipyretic and analgesic agent[1][2][3]. Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor[4].
    Acetaminophen-d3
  • HY-B0141AS
    Alpha-Estradiol-d3

    Alfatradiol-d<sub>3sub>; Epiestradiol-d<sub>3sub>; Epiestrol-d<sub>3sub>

    		 5 alpha Reductase Endogenous Metabolite Inflammation/Immunology
    Alpha-Estradiol-d3 is the deuterium labeled Alpha-Estradiol. Alpha-Estradiol is a weak estrogen and a 5α-reductase inhibitor which is used as a topical medication in the treatment of androgenic alopecia.
    Alpha-Estradiol-d3
  • HY-N0176S
    Dihydroartemisinin-d3

    Dihydroqinghaosu-d<sub>3sub>; β-Dihydroartemisinin-d<sub>3sub>; Artenimol-d<sub>3sub>

    		 Parasite NF-κB Autophagy Apoptosis Infection Cancer
    Dihydroartemisinin-d3 is the deuterium labeled Dihydroartemisinin. Dihydroartemisinin is a potent anti-malaria agent.
    Dihydroartemisinin-d3
  • HY-W008794S
    Normetanephrine-d3 hydrochloride

    (±)-Normetanephrine-d<sub>3sub> hydrochloride; DL-Normetanephrine-d<sub>3sub> hydrochloride; (Rac)-Normetanephrine-d<sub>3sub> hydrochloride

    		 Endogenous Metabolite Metabolic Disease
    Normetanephrine-d3 (hydrochloride) is the deuterium labeled Normetanephrine hydrochloride. Normetanephrine ((±)-Normetanephrine) hydrochloride is the O-methylated metabolite of norepinephrine (NE)[1].
    Normetanephrine-d3 hydrochloride
  • HY-30151S
    Methoxsalen-d3

    8-Methoxypsoralen-d<sub>3sub>; Xanthotoxin-d<sub>3sub>; 8-MOP-d<sub>3sub>

    		 Cytochrome P450 Inflammation/Immunology
    Methoxsalen-d3 is the deuterium labeled Methoxsalen[1]. Methoxsalen (8-Methoxypsoralen) is a potent tricyclic furocoumarin suicide inhibitor of CYP (cytochrome P-450), is an agent used to treat psoriasis, eczema, vitiligo and some cutaneous Lymphomas in conjunction with exposing the skin to sunlight[2].
    Methoxsalen-d3
  • HY-13777S1
    Zoledronic acid-d3

    Zoledronate-d<sub>3sub>; CGP 42446-d<sub>3sub>; CGP42446A-d<sub>3sub>; ZOL 446-d<sub>3sub>

    		 Isotope-Labeled Compounds Others
    Zoledronic acid-d3 is the deuterium labeled Zoledronic acid .
    Zoledronic acid-d3
  • HY-A0070AS3
    Liothyronine-d3

    Triiodothyronine-d<sub>3sub>; 3,3',5-Triiodo-L-thyronine-d<sub>3sub>; T3-d<sub>3sub>

    		 Endogenous Metabolite Thyroid Hormone Receptor Isotope-Labeled Compounds Endocrinology Cancer
    Liothyronine-d3 is deuterated labeled Liothyronine (HY-A0070A). Liothyronine is an active form of thyroid hormone. Liothyronine is a potent thyroid hormone receptors TRα and TRβ agonist with Kis of 2.33 nM for hTRα and hTRβ, respectively [3].
    Liothyronine-d3
  • HY-B0647S1
    Butylphthalide-d3

    3-n-Butylphthalide-d<sub>3sub>; 3-Butylphthalide-d<sub>3sub>

    		 Isotope-Labeled Compounds Neurological Disease
    Butylphthalide-d3 is the deuterium labeled Butylphthalide. Butylphthalide(3-n-Butylphthalide), an anti-cerebral-ischemia agent, is first isolated from the seeds of celery and showes efficacy in animal models of stroke.
    Butylphthalide-d3
  • HY-115127S
    3-Methylanisole-d3

    m-Methoxytoluene-d<sub>3sub>; m-Methylanisole-d<sub>3sub>

    		 Isotope-Labeled Compounds Others
    3-Methylanisole-d3 is the deuterium labeled 3-Methylanisole[1].
    3-Methylanisole-d3
  • HY-15330
    Vitamin D2-d3

    Ergocalciferol-d<sub>3sub>; Calciferol-d<sub>3sub>; VD2-d<sub>3sub>

    		 VD/VDR Metabolic Disease
    Vitamin D2-d3 (Ergocalciferol-d3) is the deuterium labeled vitamin D2.
    Vitamin D2-d3
  • HY-B0264S
    Guaifenesin-d3

    Guaiacol glyceryl ether-d<sub>3sub>; Guaiphenesin-d<sub>3sub>; Glycerol guaiacolate-d<sub>3sub>

    		 Isotope-Labeled Compounds Neurological Disease Inflammation/Immunology
    Guaifenesin-d3 is the deuterium labeled Guaifenesin. Guaifenesin (Guaiacol glyceryl ether), a constituent of guaiac resin from the wood of Guajacum officinale Linné, is an expectorant. Guaifenesin can alleviate cough discomfortby increasing sputum volume and decreasing its viscosity, thereby promoting effective cough[1][2].
    Guaifenesin-d3
  • HY-15027S
    5-Aminosalicylic Acid-d3 hydrochloride

    Mesalamine-d<sub>3sub> hydrochloride; 5-ASA-d<sub>3sub> hydrochloride; Mesalazine-d<sub>3sub> hydrochloride

    		 Isotope-Labeled Compounds PPAR PAK NF-κB Endogenous Metabolite Inflammation/Immunology Cancer
    5-Aminosalicylic Acid-d3 (hydrochloride) is the deuterium labeled 5-Aminosalicylic Acid. 5-Aminosalicylic acid (Mesalamine) hydrochloride acts as a specific PPARγ agonist and also inhibits p21-activated kinase 1 (PAK1) and NF-κB.
    5-Aminosalicylic Acid-d3 hydrochloride
  • HY-13636S
    Fulvestrant-d3

    ICI 182780-d<sub>3sub>; ZD 9238-d<sub>3sub>; ZM 182780-d<sub>3sub>

    		 Isotope-Labeled Compounds Estrogen Receptor/ERR Autophagy Apoptosis Cancer
    Fulvestrant-d3 is the deuterium labeled Fulvestrant. Fulvestrant (ICI 182780) is a pure antiestrogen and a potent estrogen receptor (ER) antagonist with an IC50 of 9.4 nM. Fulvestrant is also a GPR30 agonist. Fulvestrant effectively inhibits the growth of ER-positive MCF-7 cells with an IC50 of 0.29 nM. Fulvestrant also induces autophagy and has antitumor efficacy[1].
    Fulvestrant-d3
  • HY-10581AS
    Gatifloxacin-d3 hydrochloride

    AM-1155-d<sub>3sub> hydrochloride; BMS-206584-d<sub>3sub> hydrochloride; PD135432-d<sub>3sub> hydrochloride

    		 Isotope-Labeled Compounds Bacterial Topoisomerase Antibiotic Infection
    Gatifloxacin-d3 (hydrochloride) is the deuterium labeled Gatifloxacin (hydrochloride). Gatifloxacin hydrochloride (AM-1155; BMS-206584; PD135432) is a potent fluoroquinolone antibiotic with broad-spectrum antibacterial activity. Gatifloxacin hydrochloride inhibits bacterial type II topoisomerases (IC50=13.8 μg/ml for S. aureus topoisomerase IV) and E. coli DNA gyrase (IC50 = 0.109 μg/ml). Gatifloxacin hydrochloride can be used to treat bacterial conjunctivitis in vivo.
    Gatifloxacin-d3 hydrochloride
  • HY-17509S
    Deracoxib-d3

    SC 046-d<sub>3sub>; SC 46-d<sub>3sub>; SC 59046-d<sub>3sub>

    		 Isotope-Labeled Compounds COX Apoptosis Inflammation/Immunology
    Deracoxib-d3 is the deuterium labeled Deracoxib. Deracoxib, a selective cyclooxygenase-2 inhibitor, is a non-narcotic, non-steroidal anti-inflammatory drug (NSAID).
    Deracoxib-d3
  • HY-15027S1
    5-Aminosalicylic acid-d3

    Mesalamine-d<sub>3sub>; 5-ASA-d<sub>3sub>; Mesalazine-d<sub>3sub>

    		 Isotope-Labeled Compounds Endogenous Metabolite NF-κB PAK PPAR Inflammation/Immunology Cancer
    5-Aminosalicylic acid-d3 is the deuterium labeled 5-Aminosalicylic Acid. 5-Aminosalicylic acid (Mesalamine) acts as a specific PPARγ agonist and also inhibits p21-activated kinase 1 (PAK1) and NF-κB[1][2][3][4].
    5-Aminosalicylic acid-d3
  • HY-B0579S1
    Cyclosporin A-d3

    Cyclosporine A-d<sub>3sub>; Ciclosporin A-d<sub>3sub>; CsA-d<sub>3sub>

    		 Antibiotic Complement System Molecular Glues Phosphatase Others
    Cyclosporin A-d3 is the d3-labeled Cyclosporin A (HY-B0579)[1].
    Cyclosporin A-d3
  • HY-13757AS1
    Tamoxifen-d3

    ICI 47699-d<sub>3sub>; (Z)-Tamoxifen-d<sub>3sub>; trans-Tamoxifen-d<sub>3sub>

    		 Estrogen Receptor/ERR Apoptosis Autophagy HSP Cancer
    Tamoxifen-d3 is the deuterium labeled Tamoxifen[1]. Tamoxifen (ICI 47699) is an orally active, selective estrogen receptor modulator (SERM) which blocks estrogen action in breast cells and can activate estrogen activity in other cells, such as bone, liver, and uterine cells[2][3][4]. Tamoxifen is a potent Hsp90 activator and enhances the Hsp90 molecular chaperone ATPase activity. Tamoxifen also potent inhibits infectious EBOV Zaire and Marburg (MARV) with IC50 of 0.1 μM and 1.8 μM, respectively[6]. Tamoxifen activates autophagy and induces apoptosis[5]. Tamoxifen also can induce gene knockout of CreER(T2) transgenic mouse[7].
    Tamoxifen-d3
  • HY-B1260S2
    Cetrimonium-d3 bromide

    CTAB-d<sub>3sub>; Cetyltrimethylammonium bromide-d<sub>3sub>; Hexadecyltrimethylammonium-d<sub>3sub> bromide

    		 Isotope-Labeled Compounds Others
    Cetrimonium-d3 (bromide) is the deuterium labeled Cetrimonium bromide[1].
    Cetrimonium-d3 bromide
  • HY-B1658S
    Frovatriptan-d3 hydrochloride

    (R)-Frovatriptan-d<sub>3sub> hydrochloride; SB 209509-d<sub>3sub> hydrochloride; VML 251-d<sub>3sub> hydrochloride

    		 5-HT Receptor Neurological Disease
    Frovatriptan-d3 (hydrochloride) is the deuterium labeled Frovatriptan[1]. Frovatriptan is a potent 5-HT1B//D receptor agonist and has the highest 5-HT1B potency in the triptan class. Frovatriptan is apparently cerebroselective. Frovatriptan is efficacious and even superior in some endpoints also when taken during the headache phase in migraine attacks with aura[2].
    Frovatriptan-d3 hydrochloride
  • HY-13757S
    Tamoxifen-d3 hydrochloride

    ICI 46474-d<sub>3sub> hydrochloride; (Z)-Tamoxifen-d<sub>3sub> hydrochloride; trans-Tamoxifen-d<sub>3sub> hydrochloride

    		 Apoptosis Estrogen Receptor/ERR Autophagy HSP Isotope-Labeled Compounds Cancer
    Tamoxifen-d3 hydrochloride is deuterated labeled Tamoxifen (Citrate) (HY-13757). Tamoxifen Citrate (ICI 46474) is an orally active, selective estrogen receptor modulator (SERM) which blocks estrogen action in breast cells and can activate estrogen activity in other cells, such as bone, liver, and uterine cells [3].Tamoxifen Citrate is a potent Hsp90 activator and enhances the Hsp90 molecular chaperone ATPase activity. Tamoxifen Citrate also potent inhibits infectious EBOV Zaire and Marburg (MARV) with IC50 of 0.1 μM and 1.8 μM, respectively . Tamoxifen Citrate activates autophagy and induces apoptosis .Tamoxifen Citrate also can induce gene knockout of CreER(T2) transgenic mouse .
    Tamoxifen-d3 hydrochloride

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