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Bisphenol Z-d<sub>6</sub>

" in MedChemExpress (MCE) Product Catalog:

3878

Inhibitors & Agonists

2

Fluorescent Dye

15

Biochemical Assay Reagents

27

Peptides

1

Inhibitory Antibodies

17

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Products

16

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3705

Isotope-Labeled Compounds

4

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21

Click Chemistry

2

Oligonucleotides

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W013326S

    Isotope-Labeled Compounds Others
    Bisphenol Z-d6 is the deuterium labeled 4,4'-(Cyclohexane-1,1-diyl)diphenol (HY-W013326) .
    Bisphenol Z-d6
  • HY-W654078

    BPAF-13C<sub>12sub>; 4,4'-(Perfluoropropane-2,2-diyl)diphenol-13C<sub>12sub>

    Isotope-Labeled Compounds Others
    Bisphenol AF- 13C12 is an isotopic label of Bisphenol AF. Bisphenol AF is used in polycarbonate plastic and epoxy resin manufacturing. Bisphenol AF can significantly increase intracellular ROS levels .
    Bisphenol AF-13C12
  • HY-50895S1

    ZD1839-d<sub>6sub>

    EGFR Autophagy Cancer
    Gefitinib-d6 is the deuterium labeled Gefitinib. Gefitinib (ZD1839) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC50 of 33 nM. Gefitinib selectively inhibits EGF-stimulated tumor cell growth (IC50 of 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib also induces autophagy. Gefitinib has antitumour activity[1][2].
    Gefitinib-d6
  • HY-W011154

    Amino Acid Derivatives Others
    Z-D-2-Nal-OH is an alanine derivative .
    Z-D-2-Nal-OH
  • HY-W654082

    4,4'-Ethylidenediphenol-13C<sub>6sub>

    Isotope-Labeled Compounds Biochemical Assay Reagents Others
    Bisphenol e- 13C6 is 13C labeled Bisphenol E. Bisphenol E (4,4'-Ethylidenediphenol) is a biochemical reagent .
    Bisphenol e-13C6
  • HY-17504AS1

    ZD 4522-d<sub>6sub>

    Isotope-Labeled Compounds Autophagy Bacterial HMG-CoA Reductase (HMGCR) Potassium Channel Cardiovascular Disease Metabolic Disease Cancer
    Rosuvastatin-d6 (ZD 4522-d6) is deuterium labeled Rosuvastatin. Rosuvastatin (ZD 4522) is a competitive HMG-CoA reductase inhibitor with an IC50 of 11 nM. Rosuvastatin potently blocks hERG current with an IC50 of 195 nM, delayed cardiac repolarization, and thereby prolonged action potential durations (APDs) and corrected QT interval (QTc) intervals. Rosuvastatin reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels .
    Rosuvastatin-d6
  • HY-142555S

    Sodium 4-[1-(4-hydroxyphenyl)-1-methylethyl]phenyl sulfate-d<sub>6sub> (1:1)

    Isotope-Labeled Compounds Others
    Bisphenol A monosulfate-d6 (sodium) is the deuterium labeled Bisphenol A monosulfate sodium[1].
    Bisphenol A monosulfate-d6 sodium
  • HY-146227

    Topoisomerase Apoptosis Cancer
    DNA topoisomerase II inhibitor 1 (compound 8ed) is a potent DNA topoisomerase II inhibitor. DNA topoisomerase II inhibitor 1 shows anti-proliferative activity. DNA topoisomerase II inhibitor 1 induces apoptosis and cell cycle arrest at sub G1 phase .
    DNA topoisomerase II inhibitor 1
  • HY-RS13999

    Small Interfering RNA (siRNA) Others

    SUB1 Human Pre-designed siRNA Set A contains three designed siRNAs for SUB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    SUB1 Human Pre-designed siRNA Set A
    SUB1 Human Pre-designed siRNA Set A
  • HY-RS18793

    Small Interfering RNA (siRNA) Others
    Sub1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Sub1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
    Sub1 Mouse Pre-designed siRNA Set A
    Sub1 Mouse Pre-designed siRNA Set A
  • HY-W654077

    BPAF-d<sub>4sub>; 4,4'-(Perfluoropropane-2,2-diyl)diphenol-d<sub>4sub>

    Estrogen Receptor/ERR Endocrinology
    Bisphenol AF-d4 is the isotope labelled analog of Bisphenol AF (HY-W013782). Bisphenol AF is a full agonist for the estrogen receptor. Bisphenol AF acts as an endocrine-disrupting chemical (EDC), activating estrogen through the estrogen receptor Era. Bisphenol AF-d4 can be used for the research of endocrinology and cancer .
    Bisphenol AF-d4
  • HY-B1804S2

    Trioctanoin-d<sub>15sub>; Glyceryl trioctanoate-d<sub>15sub>

    Isotope-Labeled Compounds Endogenous Metabolite Neurological Disease Inflammation/Immunology
    Tricaprilin-d15 (Trioctanoin-d15 is the deuterium labeled Tricaprilin (HY-B1804). Tricaprilin is an orally active and well tolerated ketogenic agent that safely induces ketosis. Tricaprilin restores brain electrical activity and metabolism to help counteract neuroinflammation in migraine. Tricaprilin is promising for research of migraine prevention and Alzheimer’s disease (AD). Tricaprilin is a pure C8 medium chain triglyceride (MCT) .
    Tricaprilin-d15
  • HY-B1804S1

    Trioctanoin-d<sub>50sub>; Glyceryl trioctanoate-d<sub>50sub>

    Isotope-Labeled Compounds Endogenous Metabolite Neurological Disease Inflammation/Immunology
    Tricaprilin-d50 (Trioctanoin-d50 is the deuterium labeled Tricaprilin (HY-B1804). Tricaprilin is an orally active and well tolerated ketogenic agent that safely induces ketosis. Tricaprilin restores brain electrical activity and metabolism to help counteract neuroinflammation in migraine. Tricaprilin is promising for research of migraine prevention and Alzheimer’s disease (AD). Tricaprilin is a pure C8 medium chain triglyceride (MCT) .
    Tricaprilin-d50
  • HY-17504AS

    ZD 4522 d<sub>3sub>

    Isotope-Labeled Compounds HMG-CoA Reductase (HMGCR) Autophagy Potassium Channel Cardiovascular Disease Metabolic Disease
    Rosuvastatin-d3 is a deuterium labeled Rosuvastatin. Rosuvastatin (ZD 4522) is a competitive HMG-CoA reductase inhibitor with an IC50 of 11 nM[1]. Rosuvastatin potently blocks human ether-a-go-go related gene (hERG) current with an IC50 of 195 nM, delayed cardiac repolarization, and thereby prolonged action potential durations (APDs) and corrected QT interval (QTc) intervals[2].
    Rosuvastatin-d3
  • HY-169138

    Lipoxygenase Others
    ZD 2138 is an inhibitor of 5-lipoxygenase. ZD-2138 can alleviate bronchoconstriction induced by aspirin (HY-14654) and can be used in asthma research .
    ZD 2138
  • HY-10260S

    ZD6474-d<sub>6sub>

    Isotope-Labeled Compounds VEGFR Autophagy Apoptosis Cancer
    Vandetanib-d6 is the deuterium labeled Vandetanib. Vandetanib (D6474) is a potent, orally active inhibitor of VEGFR2/KDR tyrosine kinase activity (IC50=40 nM). Vandetanib also has activity versus the tyrosine kinase activity of VEGFR3/FLT4 (IC50=110 nM) and EGFR/HER1 (IC50=500 nM)[1].
    Vandetanib-d6
  • HY-106968

    iGluR Neurological Disease
    ZD-9379 is a potent, orally active, and brain penetrant full antagonist at the glycine site of the NMDA receptor. ZD-9379 has neuroprotective effect .
    ZD-9379
  • HY-W653930

    Bisphenol S-13C<sub>12sub>; Bis(4-hydroxyphenyl) sulfone-13C<sub>12sub>

    Isotope-Labeled Compounds Biochemical Assay Reagents Others
    4,4'-Sulfonyldiphenol- 13C12 (Bisphenol S- 13C12) is 13C labeled 4,4'-Sulfonyldiphenol. 4,4'-Sulfonyldiphenol (Bisphenol S; Bis(4-hydroxyphenyl) sulfone) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
    4,4'-Sulfonyldiphenol-13C12
  • HY-U00002A

    VEGFR Cancer
    ZD-4190 hydrochloride is a potent VEGFR inhibitor with anti-tumor activity. ZD-4190 hydrochloride can delay the growth of MDA-MB-435 tumors by inhibiting tumor cell proliferation and angiogenesis .
    ZD-4190 hydrochloride
  • HY-W013935R

    Endogenous Metabolite Endocrinology
    Bisphenol B (Standard) is the analytical standard of Bisphenol B. This product is intended for research and analytical applications. Bisphenol B is a very close structural analog of Bisphenol A (HY-18260), an endocrine disrupting chemical (EDC) and a substance of very high concern (SVHC) in the European Union (EU) for both human health. Bisphenol B shows endocrine disruptive properties or other adverse effects on animal models .
    Bisphenol B (Standard)
  • HY-W142663

    Endogenous Metabolite
    Bisphenol M is a synthetic organic compound with antioxidant activity. Bisphenol M is commonly used in industry to make plastics and resins, and is used as a stabilizer and preservative in cosmetics. Bisphenol M can also be used in certain food packaging materials to improve product durability and safety.
    Bisphenol M
  • HY-19274

    Endothelin Receptor Cardiovascular Disease Endocrinology
    ZD-1611 is a potent, orally active, selective ETA receptor antagonist, used for the research of ischemic stroke.
    ZD-1611
  • HY-18260R
    Bisphenol A (Standard)
    5+ Cited Publications

    Endogenous Metabolite Endocrinology
    Bisphenol A (Standard) is the analytical standard of Bisphenol A. This product is intended for research and analytical applications. Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders .
    Bisphenol A (Standard)
  • HY-W013935

    Endogenous Metabolite Endocrinology
    Bisphenol B is a very close structural analog of Bisphenol A (HY-18260), an endocrine disrupting chemical (EDC) and a substance of very high concern (SVHC) in the European Union (EU) for both human health. Bisphenol B shows endocrine disruptive properties or other adverse effects on animal models .
    Bisphenol B
  • HY-102093R

    Angiotensin Receptor Cardiovascular Disease Endocrinology
    ZD 7155(hydrochloride) (Standard) is the analytical standard of ZD 7155(hydrochloride). This product is intended for research and analytical applications. ZD 7155 hydrochloride is an angiotensin II receptor type 1 (AT1 receptor) antagonist.
    ZD 7155(hydrochloride) (Standard)
  • HY-10844S1

    PA-824-d<sub>5sub>; (S)-PA 824-d<sub>5sub>

    Antibiotic Bacterial Isotope-Labeled Compounds Infection Cancer
    Pretomanid-d5 is deuterated labeled Pretomanid (HY-10844). Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 μg/mL.
    Pretomanid-d5
  • HY-W008628S

    Isotope-Labeled Compounds Others
    Bisphenol AP-d5 is the deuterium labeled Bisphenol AP[1].
    Bisphenol AP-d5
  • HY-18260S1

    Endogenous Metabolite Endocrinology
    Bisphenol A-d6 is the deuterium labeled Bisphenol A. Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders[1][2][3].
    Bisphenol A-d6
  • HY-19254

    Elastase Cardiovascular Disease
    ZD-0892 is a selective and potent inhibitor of a neutrophil elastase with Kis of 6.7 and 200 nM for human neutrophil elastase and porcine pancreatic elastase, respectively.
    ZD-0892
  • HY-P10215

    Parasite Infection
    Ac-{Cpg}-Thr-Ala-{Ala(CO)}-Asp-{Cpg}-NH2 (compound 40) is a potent Plasmodium subtilisin-like protease 1 (SUB1) inhibitor. SUB1-IN-1 shows IC50 values of 12 nM and 10 nM against P. vivax and P. falciparum SUB1 (Pv- and PfSUB1), respectively .
    Ac-{Cpg}-Thr-Ala-{Ala(CO)}-Asp-{Cpg}-NH2
  • HY-18260S

    Endogenous Metabolite Endocrinology
    Bisphenol A-d16 is the deuterium labeled Bisphenol A[1]. Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders[2][3].
    Bisphenol A-d16
  • HY-18260S6

    Isotope-Labeled Compounds Endogenous Metabolite Endocrinology
    Bisphenol A-d14 is a deuterium labeled Bisphenol A (HY-18260). Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders .
    Bisphenol A-d14
  • HY-18260S4

    Endogenous Metabolite Endocrinology
    Bisphenol A-d4 is the deuterium labeled Bisphenol A[1]. Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders[2][3].
    Bisphenol A-d4
  • HY-18260S3

    Endogenous Metabolite Endocrinology
    Bisphenol A-d8 is the deuterium labeled Bisphenol A[1]. Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders[2][3][4].
    Bisphenol A-d8
  • HY-108567R

    Biochemical Assay Reagents Others
    Bisphenol A diglycidyl ether (Standard) is the analytical standard of Bisphenol A diglycidyl ether. This product is intended for research and analytical applications. Bisphenol A diglycidyl ether is used as a stabilizer and embedding agent.
    Bisphenol A diglycidyl ether (Standard)
  • HY-18260
    Bisphenol A
    5+ Cited Publications

    Endogenous Metabolite p38 MAPK Akt Reactive Oxygen Species Apoptosis Cardiovascular Disease Metabolic Disease Endocrinology Cancer
    Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cancers, cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders [6] .
    Bisphenol A
  • HY-W753532

    Isotope-Labeled Compounds Others
    Bisphenol B- 13C12 is 13C labeled Bisphenol B .
    Bisphenol B-13C12
  • HY-W778391

    Isotope-Labeled Compounds Endogenous Metabolite Cardiovascular Disease Endocrinology
    Bisphenol A- 13C2 is 13C labeled Bisphenol A. Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders .
    Bisphenol A-13C2
  • HY-102093A

    Angiotensin Receptor Others
    ZD 7155 is an AT1R selective antagonist with renal function modulating activity. The effects of ZD 7155 on glomeruli and tubules were measured in 1- (N = 9) and 6-week-old (N = 13) lambs. Pretreatment with ZD 7155 after L-NAME infusion did not alter glomerular function in 1- or 6-week-old lambs. During postnatal development, Ang II modulates the effects of NO on electrolyte handling via AT1R and AT2R. In 6-week-old lambs, selective inhibition of AT1R and AT2R increased the excretion of Na+, K+, and Cl-. In 6-week-old lambs, pretreatment with ZD 7155 and PD 123319 followed by the addition of L-NAME increased urine flow rate by 200%, free water clearance by 50%, and decreased urine osmolality by 40%. The same trends of changes in these variables were also observed when L-NAME was added to ZD 7155 or PD 123319, although to a lesser extent.
    ZD 7155
  • HY-U00002

    VEGFR EGFR Cancer
    ZD-4190 is a potent, orally available inhibitor of the vascular endothelial cell growth factor receptor 2 (VEGFR2) and of epidermal growth factor receptor (EGFR) signalling, used for the treatment of cancer.
    ZD-4190
  • HY-101320A

    ICI-D 7114 hydrochloride

    Adrenergic Receptor Endocrinology
    ZD-7114 hydrochloride is a potent and selective agonist of β3-adrenergic. ZD-7114 hydrochloride is a selective thermogenic agent in vivo. ZD-7114 hydrochloride can be used in study obesity and diabetes .
    ZD-7114 hydrochloride
  • HY-101320

    ICI-D 7114

    Adrenergic Receptor Endocrinology
    ZD-7114 is a potent and selective agonist of β3-adrenergic. ZD-7114 is a selective thermogenic agent in vivo. ZD-7114 can be used in study obesity and diabetes .
    ZD-7114
  • HY-18260S5

    Endogenous Metabolite Endocrinology
    Bisphenol A-d4-1 is the deuterium labeled Bisphenol A[1]. Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders[2][3].
    Bisphenol A-d4-1
  • HY-W654080

    α,α'-Bis(4-hydroxyphenyl)-1,4-diisopropylbenzene-13C<sub>4sub>

    Isotope-Labeled Compounds Others
    Bisphenol P- 13C4 is 13C labeled α,α'-Bis(4-hydroxyphenyl)-1,4-diisopropylbenzene .
    Bisphenol P-13C4
  • HY-W585982

    Biochemical Assay Reagents Endocrinology
    Bisphenol A-β-D-glucuronide is an inactive metabolite of the plasticizer Bisphenol A (HY-18260) .
    Bisphenol A-β-D-glucuronide
  • HY-115746

    DMBPA

    HIF/HIF Prolyl-Hydroxylase Cancer
    Dimethyl-bisphenol A (DMBPA) is a potent HIF-1α inhibitor. Dimethyl-bisphenol A can decrease Vegfa mRNA expression .
    Dimethyl-bisphenol A
  • HY-10260S2

    ZD6474-13C<sub>6sub>

    Isotope-Labeled Compounds VEGFR Autophagy Apoptosis Cancer
    Vandetanib-13C6 is a deuterated labeled Vandetanib . Vandetanib (D6474) is a potent, orally active inhibitor of VEGFR2/KDR tyrosine kinase activity (IC50=40 nM). Vandetanib also has activity versus the tyrosine kinase activity of VEGFR3/FLT4 (IC50=110 nM) and EGFR/HER1 (IC50=500 nM) .
    Vandetanib-13C6
  • HY-19156

    ICI-D 6888

    Drug Derivative Others
    ZD-6888 is an active compound.
    ZD-6888
  • HY-U00256

    Elastase Inflammation/Immunology Cancer
    ZD8321 is a potent inhibitor of human Neutrophil elastase (NE) with a Ki of 13±1.7 nM.
    ZD8321
  • HY-102093
    ZD 7155(hydrochloride)
    1 Publications Verification

    Angiotensin Receptor Cardiovascular Disease Endocrinology
    ZD 7155 hydrochloride is an angiotensin II receptor type 1 (AT1 receptor) antagonist.
    ZD 7155(hydrochloride)

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