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L-Malic acid-d<sub>3</sub>

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By Research Areas:	Cancer (776) Cardiovascular Disease (240) Endocrinology (193) Infection (407) Inflammation/Immunology (349) Metabolic Disease (471) Neurological Disease (420)
Click Chemistry:	Azide (2) Alkynes (15)
Oligonucleotides:	Flavoring Agents (1) Pre-designed siRNA Sets (1) siRNAs (1)

3405

Inhibitors & Agonists

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Isotope-Labeled Compounds

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Targets Recommended: Amino acid Transporter Amino Acid Derivatives Hydroxycarboxylic Acid Receptor (HCAR) Free Fatty Acid Receptor Fatty Acid Synthase (FASN) Apical Sodium-Dependent Bile Acid Transporter P-glycoprotein G protein-coupled Bile Acid Receptor 1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-Y1069S

*(S)-Malic* acid-d3** (S)-Hydroxybutanedioic acid-d<sub>3sub>; (S)-E 296-d<sub>3sub>; L-Malic acid-d<sub>3sub>	Endogenous Metabolite	Metabolic Disease
(S)-Malic acid-d₃ is the deuterium labeled (S)-Malic acid. (S)-Malic acid ((S)-2-Hydroxysuccinic acid) is a dicarboxylic acid in naturally occurring form, contributes to the pleasantly sour taste of fruits and is used as a food additive[1][2].

HY-16743A

*Ibiglustat (L-Malic* acid)** 2 Publications Verification Venglustat (L-Malic acid); SAR402671 (L-Malic acid); GZ402671 (L-Malic acid)	Glucosylceramide Synthase (GCS)	Metabolic Disease
Ibiglustat (Venglustat) L-Malic acid is an orally active, brain-penetrant glucosylceramide synthase (GCS) inhibitor. Ibiglustat L-Malic acid can be used for the research of Gaucher disease type 3, Parkinson's disease associated with GBA mutations, Fabry disease, GM2 gangliosidosis, and autosomal dominant polycystic kidney disease .

HY-Y1069

*(S)-Malic* acid** 1 Publications Verification (S)-Hydroxybutanedioic acid; (S)-E 296; L-Malic acid	Endogenous Metabolite	Metabolic Disease
(S)-Malic acid ((S)-2-Hydroxysuccinic acid) is a dicarboxylic acid in naturally occurring form, contributes to the pleasantly sour taste of fruits and is used as a food additive.

HY-B0302AS

Etidronic acid-d3 disodium Etidronate-d<sub>3sub> disodium; HEDPA-d<sub>3sub> disodium; HEDP-d<sub>3sub> disodium	Apoptosis Isotope-Labeled Compounds	Others
Etidronic acid-d₃ (disodium) is the deuterium labeled Etidronic acid disodium[1].

HY-103395S

Methylmalonic acid-d3 Methylpropanedioic acid-d<sub>3sub>; Methylmalonate-d<sub>3sub>	Endogenous Metabolite	Cancer
Methylmalonic acid-d₃ is the deuterium labeled Methylmalonic acid. Methylmalonic acid (Methylmalonate) is an indicator of Vitamin B-12 deficiency in cancer[1][2].

HY-18569S

3-Indoleacetic acid-d5 1 Publications Verification Indole-3-acetic acid-d<sub>5sub>; 3-IAA-d<sub>5sub>	Endogenous Metabolite Isotope-Labeled Compounds	Others
3-Indoleacetic acid-d₅ is the deuterium labeled 3-Indoleacetic acid. 3-Indoleacetic acid-d₅ can be used as internal standard for assay of IAA releases by alkaline hydrolysis of ester and amide conjugates .

HY-RS13999

SUB1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SUB1 Human Pre-designed siRNA Set A contains three designed siRNAs for SUB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SUB1 Human Pre-designed siRNA Set A SUB1 Human Pre-designed siRNA Set A

HY-146227

DNA topoisomerase II inhibitor 1	Topoisomerase Apoptosis	Cancer
DNA topoisomerase II inhibitor 1 (compound 8ed) is a potent DNA topoisomerase II inhibitor. DNA topoisomerase II inhibitor 1 shows anti-proliferative activity. DNA topoisomerase II inhibitor 1 induces apoptosis and cell cycle arrest at sub G1 phase .

HY-Y1069S3

*(S)-Malic* acid-13C4** (S)-Hydroxybutanedioic acid-¹³C<sub>4sub>; (S)-E 296-¹³C<sub>4sub>; L-Malic acid-¹³C<sub>4sub>	Isotope-Labeled Compounds	Others
(S)-Malic acid- ¹³C₄ is the ¹³C labeled S-Malic acid (HY-Y1069)[1].

HY-13777S1

Zoledronic acid-d3 Zoledronate-d<sub>3sub>; CGP 42446-d<sub>3sub>; CGP42446A-d<sub>3sub>; ZOL 446-d<sub>3sub>	Isotope-Labeled Compounds	Others
Zoledronic acid-d3 is the deuterium labeled Zoledronic acid .

HY-N0156S

Oleanolic acid-d3 Oleanic acid-d<sub>3sub>; Caryophyllin-d<sub>3sub>	Autophagy HIV Endogenous Metabolite	Cancer
Oleanolic acid-d₃ is the deuterium labeled Oleanolic Acid[1]. Oleanolic acid (Caryophyllin) is a natural compound from plants with anti-tumor activities[2].

HY-75087S

(R)-Pyrrolidine-2-carboxylic acid-d3 (+)-(R)-Proline-d<sub>3sub>; (R)-(+)-Proline-d<sub>3sub>; (R)-2-Carboxypyrrolidine-d<sub>3sub>; (R)-Proline-d<sub>3sub>	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
(R)-Pyrrolidine-2-carboxylic acid-d₃ is the deuterium labeled (R)-pyrrolidine-2-carboxylic acid. (R)-pyrrolidine-2-carboxylic acid is an endogenous metabolite.

HY-15027S

5-Aminosalicylic Acid-d3 hydrochloride Mesalamine-d<sub>3sub> hydrochloride; 5-ASA-d<sub>3sub> hydrochloride; Mesalazine-d<sub>3sub> hydrochloride	Isotope-Labeled Compounds PPAR PAK NF-κB Endogenous Metabolite	Inflammation/Immunology Cancer
5-Aminosalicylic Acid-d₃ (hydrochloride) is the deuterium labeled 5-Aminosalicylic Acid. 5-Aminosalicylic acid (Mesalamine) hydrochloride acts as a specific PPARγ agonist and also inhibits p21-activated kinase 1 (PAK1) and NF-κB.

HY-W154267S

3-Aminoisobutyric acid-d3 hydrochloride β-Aminoisobutyric acid-d<sub>3sub> hydrochloride; BAIBA-d<sub>3sub> hydrochloride	Isotope-Labeled Compounds	Others
3-Aminoisobutyric acid-d₃ (hydrochloride) is the deuterium labeled DL-Histidine[1].

HY-W004282S1

Undecanoic acid-d3 Undecanoate-d<sub>3sub>; Hendecanoic acid-d<sub>3sub>	Isotope-Labeled Compounds Fungal Endogenous Metabolite	Infection
Undecanoic acid-d₃ is the deuterium labeled Undecanoic acid. Undecanoic acid (Undecanoate) is a monocarboxylic acid with antimycotic property, which inhibits the production of exocellular keratinase, lipase and the biosynthesis of several phospholipids in T. rubrum[1].

HY-I0746S

3-Aminobenzoic acid-d4 m-Aminobenzoic acid-d<sub>4sub>; 3ABA-d<sub>4sub>	Endogenous Metabolite	Others
3-Aminobenzoic acid-d₄ is the deuterium labeled 3-Aminobenzoic acid[1].

HY-15027S1

5-Aminosalicylic acid-d3 Mesalamine-d<sub>3sub>; 5-ASA-d<sub>3sub>; Mesalazine-d<sub>3sub>	Isotope-Labeled Compounds Endogenous Metabolite NF-κB PAK PPAR	Inflammation/Immunology Cancer
5-Aminosalicylic acid-d₃ is the deuterium labeled 5-Aminosalicylic Acid. 5-Aminosalicylic acid (Mesalamine) acts as a specific PPARγ agonist and also inhibits p21-activated kinase 1 (PAK1) and NF-κB[1][2][3][4].

HY-13318S

Oseltamivir acid-d3 Maximum Cited Publications 56 Publications Verification GS 4071-d<sub>3sub>; Ro 64-0802-d<sub>3sub>; Oseltamivir carboxylate-d<sub>3sub>	Influenza Virus	Infection
Oseltamivir acid-d₃ is a deuterium labeled Oseltamivir acid. Oseltamivir acid, the active metabolite of Oseltamivir phosphate, is an orally bioavailable, potent and selective inhibitor of influenza virus neuraminidase (IC50=2 nM) with activity against both influenza A and B viruses[1][2].

HY-Y1311S

Malic acid-d3 Hydroxybutanedioic acid-d<sub>3sub>; E 296-d<sub>3sub>	Endogenous Metabolite	Others
Malic acid-d₃ is the deuterium labeled Malic acid. Malic acid (Hydroxybutanedioic acid) is a dicarboxylic acid that is naturally found in fruits such as apples and pears. It plays a role in many sour or tart foods[1][2].

HY-Y0084S

3,4,5-Trimethoxybenzoic acid-d3 Eudesmic acid-d<sub>3sub>; Trimethylgallic acid-d<sub>3sub>	Isotope-Labeled Compounds	Others
3,4,5-Trimethoxybenzoic acid-d₃ is the deuterium labeled 3,4,5-Trimethoxybenzoic acid[1]. 3,4,5-Trimethoxybenzoic acid (Eudesmic acid;Trimethylgallic Acid) is a benzoic acid derivative. A building block in medicine and organic synthesis.

HY-158995S1

3-Epiglycyrrhetinic acid-d3 3α-Glycyrrhetic acid-d<sub>3sub>	Isotope-Labeled Compounds	Others
3-Epiglycyrrhetinic acid-d3 (3α-Glycyrrhetic acid-d3) is the deuterium-labeled 3-Epiglycyrrhetinic acid. 3-Epiglycyrrhetinic acid is a derivative of glycyrrhetic acid. Glycyrrhetic acid and its derivative are considered to have anti-inflammatory, anti-ulcer, and antiviral activities .

HY-10844S1

Pretomanid-d5 PA-824-d<sub>5sub>; (S)-PA 824-d<sub>5sub>	Antibiotic Bacterial Isotope-Labeled Compounds	Infection Cancer
Pretomanid-d₅ is deuterated labeled Pretomanid (HY-10844). Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 μg/mL.

HY-18569S1

3-Indoleacetic acid-d4 Indole-3-acetic acid-d<sub>4sub>; 3-IAA-d<sub>4sub>	Isotope-Labeled Compounds	Others
3-Indoleacetic acid-d₄ (Indole-3-acetic acid-d₄; 3-IAA-d₄)is the deuterium labeled3-Indoleacetic acid(HY-18569) . 3-Indoleacetic acid (Indole-3-acetic acid) is the most common natural plant growth hormone of the auxin class. It can be added to cell culture medium to induce plant cell elongation and division .

HY-B0421S

Mycophenolic acid-d3 Mycophenolate-d<sub>3sub>	Bacterial Apoptosis Fungal Antibiotic Endogenous Metabolite Isotope-Labeled Compounds Flavivirus	Others
Mycophenolic acid-d₃ is deuterium labeled Mycophenolic acid, which is an an immunosuppresant agent and has potent anti-proliferative activity.

HY-113335S

Trihydroxycholestanoic acid-d3 Coprocholic acid-d<sub>3sub>	Endogenous Metabolite Isotope-Labeled Compounds	Others
Trihydroxycholestanoic acid-d₃ is the deuterium labeled Trihydroxycholestanoic acid[1].

HY-B1053S

Iotalamic acid-d3 Iothalamic acid-d<sub>3sub>	Isotope-Labeled Compounds	Inflammation/Immunology
Iotalamic acid-d₃ is the deuterium labeled Iotalamic acid[1].

HY-P10215

Ac-{Cpg}-Thr-Ala-{Ala(CO)}-Asp-{Cpg}-NH2	Parasite	Infection
Ac-{Cpg}-Thr-Ala-{Ala(CO)}-Asp-{Cpg}-NH2 (compound 40) is a potent **Plasmodium subtilisin-like protease 1 (SUB1)** inhibitor. SUB1-IN-1 shows IC₅₀ values of 12 nM and 10 nM against P. vivax and P. falciparum SUB1 (Pv- and PfSUB1), respectively .

HY-Y1088S3

Hydrocinnamic acid-d5 3-Phenylpropionic acid-d<sub>5sub>; 3-Phenylpropanoic acid-d<sub>5sub>; 3-Phenyl-n-propionic acid-d<sub>5sub>	Endogenous Metabolite	Others
Hydrocinnamic acid-d₅ is the deuterium labeled Hydrocinnamic acid[1]. Hydrocinnamic acid is the major rhizospheric compound with known growth regulatory activities[2].

HY-15027S3

5-Aminosalicylic acid-d3 disodium Mesalamine-d<sub>3sub> disodium; 5-ASA-d<sub>3sub> disodium; Mesalazine-d<sub>3sub> disodium	PPAR NF-κB Endogenous Metabolite PAK Isotope-Labeled Compounds	Inflammation/Immunology
5-Aminosalicylic acid-d₃ disodium is deuterated labeled 5-Aminosalicylic Acid (HY-15027). 5-Aminosalicylic acid (Mesalamine) acts as a specific PPARγ agonist and also inhibits p21-activated kinase 1 (PAK1) and NF-κB.5-Aminosalicylic acid can inhibit the activity of osteopontin (OPN).

HY-Y1088S2

Hydrocinnamic acid-d9 3-Phenylpropionic acid-d<sub>9sub>; 3-Phenylpropanoic acid-d<sub>9sub>; 3-Phenyl-n-propionic acid-d<sub>9sub>	Endogenous Metabolite	Others
Hydrocinnamic acid-d₉ is the deuterium labeled Hydrocinnamic acid[1]. Hydrocinnamic acid is the major rhizospheric compound with known growth regulatory activitie[2]s.

HY-113371AS

2-Methylcitric acid-d3 trisodium Methylcitric acid-d<sub>3sub> trisodium	Endogenous Metabolite Isotope-Labeled Compounds	Metabolic Disease
2-Methylcitric acid-d₃ (Methylcitric acid-d₃) trisodium is deuterium-labeled 2-Methylcitric acid (trisodium) (HY-113371A) .

HY-N0184S

Glycyrrhizic acid-d3 Glycyrrhizin-d<sub>3sub>	Isotope-Labeled Compounds Virus Protease	Metabolic Disease Cancer
Glycyrrhizic acid-d₃ (Glycyrrhizin-d₃) is deuterium labeled Glycyrrhizic acid. Glycyrrhizic acid is a triterpenoid saponinl, acting as a direct HMGB1 antagonist, with anti-tumor, anti-diabetic activities .

HY-N0384S4

Homovanillic acid-d3-1 Vanilacetic acid-d<sub>3sub>-1	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
Homovanillic acid-d3-1 (Vanilacetic acid-d3-1) is deuterated labeled Homovanillic acid (HY-N0384). Homovanillic acid is a dopamine metabolite associated with aromatic amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and adiponectin reductase deficiency .

HY-18569S3

3-Indoleacetic acid-d7 Indole-3-acetic acid-d<sub>7sub>; 3-IAA-d<sub>7sub>	Endogenous Metabolite Molecular Glues	Others
3-Indoleacetic acid-d₇ is the deuterium labeled 3-Indoleacetic acid[1]. 3-Indoleacetic acid (Indole-3-acetic acid) is the most common natural plant growth hormone of the auxin class. It can be added to cell culture medium to induce plant cell elongation and division .

HY-119695AS2

Simvastatin acid-d3 ammonium Tenivastatin-d<sub>3sub> ammonium	Reactive Oxygen Species HMG-CoA Reductase (HMGCR) Isotope-Labeled Compounds	Inflammation/Immunology
Simvastatin acid-d₃ (Tenivastatin-d₃) ammonium is deuterium-labeled Simvastatin acid (ammonium) (HY-119695A) .

HY-Y1313S

3-Nitrobenzoic acid-d4 m-Carboxynitrobenzene-d<sub>4sub>; m-Nitrobenzenecarboxylic acid-d<sub>4sub>; m-Nitrobenzoic acid-d<sub>4sub>	Isotope-Labeled Compounds	Others
3-Nitrobenzoic acid-d₄ is the deuterium labeled 3-Nitrobenzoic acid[1].

HY-N0384S

Homovanillic acid-d3 Vanilacetic acid-d<sub>3sub>	Endogenous Metabolite	Metabolic Disease
Homovanillic acid-d₃ is the deuterium labeled Homovanillic acid. Homovanillic acid is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency.

HY-41417S1

Octanoic acid-d3 Caprylic acid-d<sub>3sub>	Endogenous Metabolite	Metabolic Disease
Octanoic acid-d₃ is the deuterium labeled Octanoic acid. Octanoic acid (Caprylic acid) is an oily liquid with a slightly unpleasant rancid taste and used commercially in the production of esters used in perfumery and also in the manufacture of dyes.

HY-158995S

3-Epiglycyrrhetinic acid-d2 3α-Glycyrrhetic acid-d<sub>2sub>	Isotope-Labeled Compounds	Others
3-Epiglycyrrhetinic acid-d2 (3α-Glycyrrhetic acid-d2) is the deuterium-labeled 3-Epiglycyrrhetinic acid. 3-Epiglycyrrhetinic acid is a derivative of glycyrrhetic acid. Glycyrrhetic acid and its derivative are considered to have anti-inflammatory, anti-ulcer, and antiviral activities .

HY-Y0957S

2,5-Difluorobenzoic acid-d3 NSC 190310-d<sub>3sub>	Isotope-Labeled Compounds	Others
2,5-Difluorobenzoic acid-d₃ is the deuterium labeled 2,5-Difluorobenzoic acid[1].

HY-107494S2

4-Oxoretinoic acid-d3 4-Keto retinoic acid-d<sub>3sub>	Isotope-Labeled Compounds	Others
4-Oxoretinoic acid-d₃ is the deuterium labeled 4-Oxoretinoic acid[1].

HY-W004260S2

Arachidic acid-d3 Icosanoic acid-d<sub>3sub>	Isotope-Labeled Compounds Endogenous Metabolite	Others
Arachidic acid-d₃) is the deuterium labeled Arachidic acid. Arachidonic acid (Icosanoic acid), a long-chain fatty acid, is present in all mammalian cells, typically esterified to membrane phospholipids, and is one of the most abundant polyunsaturated fatty acids present in human tissue[1][2].

HY-N7057S1

Nonanoic acid-d3 Pelargonic acid-d<sub>3sub>	Isotope-Labeled Compounds Bacterial	Infection
Nonanoic acid-d₃ is the deuterium labeled Nonanoic acid. Nonanoic acid is a naturally-occurring saturated fatty acid with nine carbon atoms. Nonanoic acid significantly reduces bacterial translocation, enhances antibacterial activity, and remarkably increases the secretion of porcine β-defensins 1 (pBD-1) and pBD-2[1].

HY-121883S1

Lignoceric acid-d3 Tetracosanoic acid-d<sub>3sub>	Endogenous Metabolite	Neurological Disease
Lignoceric acid-d₃ is the deuterium labeled Lignoceric acid[1]. Lignoceric acid (Tetracosanoic acid) is a 24-carbon saturated (24:0) fatty acid, which is synthesized in the developing brain. Lignoceric acid is also a by-product of lignin production. Lignoceric acid can be used for Zellweger cerebro‐hepato‐renal syndrome and adrenoleukodystrophy research[2][3].

HY-W091636S

3,3'-Azanediyldipropionic acid-d8 3,3'-Iminodipropionic acid-d<sub>8sub>	Isotope-Labeled Compounds	Others
3,3'-Azanediyldipropionic acid-d₈ is the deuterium labeled 3,3'-Azanediyldipropionic acid[1].

HY-101411S

4-Acetamidobutanoic acid-d3 N-acetyl GABA-d<sub>3sub>	Bacterial GABA Receptor Endogenous Metabolite Isotope-Labeled Compounds	Others
4-Acetamidobutanoic acid-d3 is the deuterated analog of 4-Acetamidobutanoic acid (HY-101411). 4-Acetamidobutanoic acid (N-acetyl GABA), the main metabolite of GABA, exhibits antioxidant and antibacterial activities .

HY-76547S2

p-Toluic acid-d3 4-Methylbenzoic acid-d<sub>3sub>	Endogenous Metabolite	Others
p-Toluic acid-d3 is the deuterium labeled p-Toluic acid[1]. p-Toluic acid (4-Methylbenzoic acid) is a substituted benzoic acid and can be used as an intermediate for the synthesis of para-aminomethylbenzoic acid (PAMBA), p-tolunitrile, etc.

HY-W018728S

3,5-Dimethylbenzoic acid-d9 m-Xylene-5-carboxylic acid-d<sub>9sub>	Isotope-Labeled Compounds	Others
3,5-Dimethylbenzoic acid-d₉ is the deuterium labeled 3,5-Dimethylbenzoic acid[1].

HY-B1689AS

Methantheline-d3 bromide MTB 51-d<sub>3sub>; Mantheline-d<sub>3sub>; Metantyl-d<sub>3sub>; Metanyl-d<sub>3sub>; Metaxan-d<sub>3sub>; Methanide-d<sub>3sub>	Isotope-Labeled Compounds	Others
Methantheline-d₃ (bromide) is the deuterium labeled Methantheline bromide[1].

HY-78985S

Benzene-1,3,5-tricarboxylic acid-d3 Trimesic acid-d<sub>3sub>	Isotope-Labeled Compounds	Others
Benzene-1,3,5-tricarboxylic acid-d₃ is the deuterium labeled Benzene-1,3,5-tricarboxylic acid[1].

Cat. No.	Product Name	Type

HY-109541S2

1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d9 DMPC-d<sub>9sub>	Drug Delivery
1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d₉ is deuterium labeled 1,2-Dimyristoyl-sn-glycero-3-phosphocholine. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) is a synthetic phospholipid used in liposomes. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine

HY-W034392

Stewart-Grubbs catalyst

Biochemical Assay Reagents

Stewart-Grubbs catalyst is an effective catalyst for the cross-metathesis of olefins with a large number of allylic substituents. In addition, ChemBeads are chemically coated glass beads that improve flowability and chemical homogeneity, making them ideal for automated solid dispensing and high-throughput experiments. Notably, the manufacture of ChemBeads does not require additional chemicals or surfactants, allowing for precise dispensing of sub-milligram amounts of catalyst.

HY-109541S

1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d58 DMPC-d<sub>58sub>	Drug Delivery
1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d₅₈ is deuterium labeled 1,2-Dimyristoyl-sn-glycero-3-phosphocholine. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) is a synthetic phospholipid used in liposomes. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine

HY-109541S1

1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d4 DMPC-d<sub>4sub>	Drug Delivery
1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d₄ is deuterium labeled 1,2-Dimyristoyl-sn-glycero-3-phosphocholine. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) is a synthetic phospholipid used in liposomes. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine

HY-109541S3

1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d13 DMPC-d<sub>13sub>	Drug Delivery
1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d₁₃ is deuterium labeled 1,2-Dimyristoyl-sn-glycero-3-phosphocholine. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) is a synthetic phospholipid used in liposomes. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine

HY-109541S4

1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d63 DMPC-d<sub>63sub>	Drug Delivery
1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d₆₃ is deuterium labeled 1,2-Dimyristoyl-sn-glycero-3-phosphocholine. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) is a synthetic phospholipid used in liposomes. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine

HY-109541S5

1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d67 DMPC-d<sub>67sub>	Drug Delivery
1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d₆₇ is deuterium labeled 1,2-Dimyristoyl-sn-glycero-3-phosphocholine. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) is a synthetic phospholipid used in liposomes. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine

HY-109541S6

(Rac)-1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d72 (Rac)-DMPC-d<sub>72sub>	Drug Delivery
(Rac)-1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d₇₂ is deuterium labeled (Rac)-1,2-Dimyristoyl-sn-glycero-3-phosphocholine. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) is a synthetic phospholipid used in liposomes. 1,2-Dimyristoyl-sn-glycero-3-ph

Cat. No.	Product Name	Target	Research Area

HY-P2274

Argifin	Parasite	Infection
Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms, with IC₅₀s of 0.025 μM, 6.4 μM , 1.1 μM and 4.5 μM for SmChiA (Serratia marcescens chitinaese A), SmChiB, Aspergillus fumigatus chitinase B1 and human chitotriosidase, respectively .

HY-N2466

Melanotan I 1 Publications Verification MT-I; [Nle4,D-Phe7]-α-MSH	Melanocortin Receptor	Neurological Disease Cancer
Melanotan I is a potent non-selective melanocortin receptor (MCR) agonist. Melanotan I is a synthetic analogue of α-melanocyte stimulating hormone (α-MSH) that stimulates melanogenesis. Melanotan I can induce skin tanning by mimicking the actions of a-MSH on the melanocortin type 1 receptors (MC1R) of melanocytes. Melanotan I can be used for the research of sun-induced skin cancer, melanoma, inflammation and male erectile dysfunction ^[3] .

HY-P0090S

Calcitonin-13C6,15N4 (salmon) TFA Salmon calcitonin-¹³C<sub>6sub>,¹⁵N<sub>4sub> TFA	CGRP Receptor	Metabolic Disease
Calcitonin- ¹³CIC₆, ¹⁵NIC₄ (salmon) (Salmon calcitonin- ¹³CIC₆, ¹⁵NIC₄) TFA is ¹³C and ¹⁵N-labeled Calcitonin (salmon) (HY-P0090). Calcitonin (salmon) , a calcium regulating hormone, is a dual-action amylin and calcitonin receptor agonist, could stimulate bone formation and inhibit bone resorption .

HY-P10218A

MANS peptide TFA	MARCKS PKC	Inflammation/Immunology Cancer
MANS peptide TFA is the TFA salt form of MANS peptide (HY-P10218). MANS peptide TFA is an inhibitor for myristoylated alanine-rich C kinase substrate (MARCKS), which competes with MARCKS in cells for membrane binding, and thus inhibits the stimulation of mucin secretion and tumor metastasis .

HY-P10215

Ac-{Cpg}-Thr-Ala-{Ala(CO)}-Asp-{Cpg}-NH2	Parasite	Infection
Ac-{Cpg}-Thr-Ala-{Ala(CO)}-Asp-{Cpg}-NH2 (compound 40) is a potent **Plasmodium subtilisin-like protease 1 (SUB1)** inhibitor. SUB1-IN-1 shows IC₅₀ values of 12 nM and 10 nM against P. vivax and P. falciparum SUB1 (Pv- and PfSUB1), respectively .

HY-P3426

BACE1-IN-10	Beta-secretase	Cancer
BACE1-IN-10 is a potent BACE1 Inhibitor. BACE1-IN-10 shows sub-micromolar activity against recombinant BACE1 (rBACE1) .

HY-W005541S1

3-Ethylphenylboronic acid-d5 B-(3-Ethylphenyl)-Boronic acid-d5	Isotope-Labeled Compounds	Others
3-Ethylphenylboronic acid-d5 (B-(3-Ethylphenyl)-Boronic acid-d5) is a deuterium labeled 3-Ethylphenylboronic acid.

HY-P10218

MANS peptide	MARCKS PKC	Inflammation/Immunology Cancer
MANS peptide is an inhibitor for myristoylated alanine-rich C kinase substrate (MARCKS), which competes with MARCKS in cells for membrane binding, and thus inhibits the stimulation of mucin secretion and tumor metastasis .

HY-P10318

SHR-2042	GLP Receptor	Endocrinology
SHR-2042 is a selective agonist of the GLP-1 receptor.SHR-2042 improves glycemic control by activating the GLP-1 receptor, enhancing insulin secretion and inhibiting glucagon secretion. SHR-2042 combined with sodium N-(8-[2-hydroxybenzoyl] amino) caprylate (SNAC) promotes monomerization through the formation of micelles and improves oral absorption efficiency .

HY-P4837

Ac-Lys-D-Ala-D-lactic acid	Peptides	Others
Ac-Lys-D-Ala-D-lactic acid is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P10200

CP7-FP13-2	Bacterial	Infection
CP7-FP13-2 is a peptide with antivirulence factor and antibacterial activity. CP7-FP13-2 inhibits the formation of Staphylococcus aureus biofilm and has good antibacterial efficacy in mice .

HY-P0041

F992	Vasopressin Receptor	Neurological Disease
F992 is an antidiuretic peptide and vasopressin (antidiuretic hormone) analogue .

HY-P0041A

F992 TFA	Vasopressin Receptor	Neurological Disease
F992 TFA is an antidiuretic peptide and vasopressin (antidiuretic hormone) analogue .

HY-P3462

Cagrilintide	CGRP Receptor	Metabolic Disease
Cagrilintide is an investigational novel long-acting acylated amylin analogue, acts as nonselective amylin receptors (AMYR) and calcitonin G protein-coupled receptor (CTR) agonist. Cagrilintide induces significant weight loss and reduces food intake. Cagrilintide has the potential for the research of obesity ^[3].

HY-P3462A

Cagrilintide acetate	CGRP Receptor	Metabolic Disease
Cagrilintide acetate is a non-selective AMYR/CTR agonist and long-acting acylated amylase analogue. Cagrilintide acetate causes a reduction in food intake and significant weight loss in a dose-dependent manner. Cagrilintide acetate can be used in obesity studies ^[3].

HY-P5161A

FC382K10W15 TFA	GCGR	Metabolic Disease
FC382K10W15 TFA is a glucagon analogue and GLP-1R/GCGR agonist. FC382K10W15 TFA can be used in type 2 diabetes research .

HY-P5161

FC382K10W15	Peptides	Metabolic Disease
FC382K10W15 is a glucagon derivative useful for diabetes research .

HY-P10271

RG7697	GLP Receptor	Metabolic Disease
RG7697 is a dual agonist for glucagon-like peptide receptor (GLP Receptor) and glucosedependent insulinotropic polypeptide receptor (GIPR), with EC₅₀ of 5 and 3 pM, respectively. RG7697 exhibits antihyperglycemic property .

HY-P3143

BMSpep-57	PD-1/PD-L1	Cancer
BMSpep-57 is a potent and competitive macrocyclic peptide inhibitor of PD-1/PD-L1 interaction with an IC₅₀?of 7.68?nM. BMSpep-57 binds to PD-L1 with K_ds of 19 nM and 19.88 nM in MST?and SPR assays, respectively.?BMSpep-57?facilitates T cell function by in creasing IL-2 production in PBMCs .

HY-P3143A

BMSpep-57 hydrochloride	PD-1/PD-L1	Cancer
BMSpep-57 hydrochloride is a potent and competitive macrocyclic peptide inhibitor of PD-1/PD-L1 interaction with an IC₅₀ of 7.68?nM. BMSpep-57 hydrochloride binds to PD-L1 with K_ds of 19 nM and 19.88 nM in MST and SPR assays, respectively. BMSpep-57 hydrochloride facilitates T cell function by in creasing IL-2 production in PBMCs .

HY-P10341

ZP3022	GCGR	Metabolic Disease
ZP3022 is a dual agonist of glucagon-like peptide-1 (GLP-1) and gastrin that has the ability to sustainably improve glycemic control. Additionally, ZP3022 can effectively increase β-cell mass, promote β-cell proliferation, and enhance the function of pancreatic islets. ZP3022 can be used in anti-diabetic research .

HY-P10381

palm11-TTDS-PrRP31	Peptides	Others
palm11-TTDS-PrRP31 is a strong agonist of GPR10 (EC₅₀: 84 pM). palm11-TTDS-PrRP31 has long-lasting anorexigenic effects .

HY-P4146A

Survodutide TFA BI 456906 TFA	GLP Receptor GCGR	Metabolic Disease
Survodutide (BI 456906) TFA is a potent, selective glucagon receptor/GLP-1 receptor (GCGR/GLP-1R) dual agonist with EC₅₀s of 0.52 nM and 0.33 nM in CHO-K1 cells, respectively. Survodutide TFA, a 29-amino-acid peptide, is a potent acylated peptide containing a C18 fatty acid. Survodutide TFA has robust anti-obesity efficacy achieved by increasing energy expenditure and decreasing food intake .

HY-P4146

Survodutide BI 456906	GLP Receptor GCGR	Metabolic Disease
Survodutide (BI 456906) is a potent, selective glucagon receptor/GLP-1 receptor (GCGR/GLP-1R) dual agonist with EC₅₀s of 0.52 nM and 0.33 nM in CHO-K1 cells, respectively. Survodutide, a 29-amino-acid peptide, is a potent acylated peptide containing a C18 fatty acid. Survodutide has robust anti-obesity efficacy achieved by increasing energy expenditure and decreasing food intake .

HY-113560

Plipastatin B1	Antibiotic Fungal Phospholipase	Infection
Plipastatin B1 is a lipopeptide antibiotic, an inhibitor of phospholipase A₂ (PLA2), which has antifungal activity .

HY-P1162

(d(CH2)51,Tyr(Me)2,Arg8)-Vasopressin SKF 100273	Vasopressin Receptor	Metabolic Disease
(d(CH2)51,Tyr(Me)2,Arg8)-Vasopressin (SKF 100273) is a vasopressin V1 receptor selective antagonist .

HY-P2595

SKF 103784	Peptides	Cardiovascular Disease
SKF 103784 is an vasopressin antagonist with activity against vasopressin. SKF 103784 inhibits the physiological response caused by antidiuretic and is therefore used to study biological processes related to water and salt balance. SKF 103784 can also be used to explore pathological mechanisms related to cardiovascular diseases and endocrine dysfunction .

HY-P10031

SAR441255	GLP Receptor GCGR	Metabolic Disease
SAR441255 is a potent unimolecular peptide GLP-1/GIP/GCG receptor triagonist. SAR441255 displays high potency with balanced activation of all three target receptors.?SAR441255 shows positive acute glucoregulatory effectss in diabetic obese monkeys .

HY-P10031A

SAR441255 TFA	GLP Receptor GCGR	Metabolic Disease
SAR441255 TFA is a potent unimolecular peptide GLP-1/GIP/GCG receptor triagonist. SAR441255 TFA displays high potency with balanced activation of all three target receptors. SAR441255 TFA shows positive acute glucoregulatory effectss in diabetic obese monkeys .

HY-P4895

(d(CH2)51,Tyr(Me)2,Orn8)-Oxytocin	Oxytocin Receptor	Neurological Disease
(d(CH2)51,Tyr(Me)2,Orn8)-Oxytocin (OVT) is an oxytocin receptor antagonist. (d(CH2)51,Tyr(Me)2,Orn8)-Oxytocin can be used for the research of neurological disease .

HY-P10272

Rusfertide PTG-300	Ferroportin	Others
Rusfertide is a peptide mimetic of natural hepcidin, which targets and degrades ferroportin, reduces serum iron and transferrin-saturation, and thus regulates the production of red blood cells. Rusfertide ameliorates the polycythemia vera, β-thalassemia and hereditary hemochromatosis .

HY-P10563

Noraramtide BHV-1100	CD38	Cancer
Noraramtide (BHV-1100) is an antibody recruitment molecule. Noraramtide can specifically bind to CD38 molecules to recruit natural killer (NK) cells. Noraramtide enhances the ability of NK cells to kill tumor cells through antibody-dependent cellular cytotoxicity (ADCC). This mechanism allows NK cells to more effectively recognize and eliminate tumor cells while avoiding mutual killing between NK cells. Noraramtide can be used for the study of autologous cancer immunity .

Cat. No.	Product Name	Target	Research Area

HY-P99294

Ganitumab AMG 479; Human Anti-IGF1R Recombinant Antibody	IGF-1R	Cancer
Ganitumab (AMG 479) is a recombinant human monoclonal antibody to the human type 1 insulin-like growth factor receptor (IGF1R). Ganitumab recognizes murine IGF1R with sub-nanomolar affinity (K_D=0.22 nM) and inhibits the interaction of murine IGF1R with IGF1 and IGF2. Ganitumab can be used in research of cancer .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-Y1069

*(S)-Malic* acid** 1 Publications Verification (S)-Hydroxybutanedioic acid; (S)-E 296; L-Malic acid	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
(S)-Malic acid ((S)-2-Hydroxysuccinic acid) is a dicarboxylic acid in naturally occurring form, contributes to the pleasantly sour taste of fruits and is used as a food additive.

HY-125833

Alpha-Naphthoflavone 5+ Cited Publications	Flavonoids Flavones Source classification Indigofera heterantha Wall. ex Brand. Plants Compositae Disease Research Fields Cancer	Cytochrome P450 Aryl Hydrocarbon Receptor Apoptosis
Alpha-Naphthoflavone is an orally active flavonoid that is a potent, competitive inhibitor of aromatase< b>aromatase. < b > IC < sub > 50 < / sub > < / b > and < b > K < sub > I < / sub > < / b > value were 0.5 and 0.2 microns. Alpha-Naphthoflavone can inhibit cell proliferation and induce apoptosis ^[3] .

HY-B0504S

Creatinine-d3 3 Publications Verification NSC13123-d<sub>3sub>	Classification of Application Fields Metabolic Disease Disease Research Fields	Endogenous Metabolite
Creatinine-d₃ is a deuterium labeled Creatinine. Creatinine is a break-down product of creatine phosphate in muscle[1].

HY-W011474

Geranylgeraniol	Structural Classification Natural Products Microorganisms	NF-κB
Geranylgeraniol is an orally acitve vitamin K₂ sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model ^[3] .

HY-P2274

Argifin	Infection Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields	Parasite
Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms, with IC₅₀s of 0.025 μM, 6.4 μM , 1.1 μM and 4.5 μM for SmChiA (Serratia marcescens chitinaese A), SmChiB, Aspergillus fumigatus chitinase B1 and human chitotriosidase, respectively .

HY-N0662

Amentoflavone Maximum Cited Publications 9 Publications Verification Didemethyl-ginkgetin	Structural Classification Flavonoids Classification of Application Fields Source classification Phenols Polyphenols Selaginellaceae Plants Biflavones Selaginella tamariscina (P. Beauv.) Spring Disease Research Fields Cancer	Reactive Oxygen Species Apoptosis Bacterial Fungal RSV GABA Receptor
Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active GABA(A) negative modulator. Amentoflavone also shows anti-inflammatory, antioxidative, anti-viral, anti-tumor, anti-radiation, anti-fungal, antibacterial activity. Amentoflavone induces apoptosis and cell cycle arrest at sub-G1 phase ^[3] .

HY-20558

*D-(+)-Malic* acid** D-Malic acid	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Malus pumila Mill. Source classification Rosaceae Metabolic Disease Plants Disease Research Fields	Endogenous Metabolite
D-(+)-Malic acid (D-Malic acid), an active enantiomer of Malic acid, is a competitive inhibitor of L(--)malic acid transport .

HY-N11799

Neochilenin 3-O-Methylquercetin 4′-O-glucoside	Structural Classification Flavonoids Source classification Plants Compositae Other Flavonoids	Others
Neochilenin (3-O-Methylquercetin 4 '-O-glucoside) is a glycoside of 3-O-methylquercetin, which can be isolated from the sub-family Cereoideae (Cactaceae). .

HY-N10192

Aculene D	Infection Microorganisms Classification of Application Fields Terpenoids Sesquiterpenes Source classification Disease Research Fields	Endogenous Metabolite Bacterial
Aculene D, a fungal metabolite, shows quorum sensing (QS) inhibitory activity against Chromobacterium violaceum CV026, and could significantly reduce violacein production in N-hexanoyl-l-homoserine lactone (C6-HSL) induced C. violaceum CV026 cultures at sub-inhibitory concentrations .

HY-W011474R

Geranylgeraniol (Standard)	Structural Classification Natural Products Microorganisms	NF-κB
Geranylgeraniol (Standard) is the analytical standard of Geranylgeraniol. This product is intended for research and analytical applications. Geranylgeraniol is an orally acitve vitamin K2 sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model ^[3][4].

HY-N0662R

Amentoflavone (Standard)	Structural Classification Flavonoids Source classification Phenols Polyphenols Selaginellaceae Plants Biflavones Selaginella tamariscina (P. Beauv.) Spring	Reactive Oxygen Species Apoptosis Bacterial Fungal RSV GABA Receptor
Amentoflavone (Standard) is the analytical standard of Amentoflavone. This product is intended for research and analytical applications. Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active GABA(A) negative modulator. Amentoflavone also shows anti-inflammatory, antioxidative, anti-viral, anti-tumor, anti-radiation, anti-fungal, antibacterial activity. Amentoflavone induces apoptosis and cell cycle arrest at sub-G1 phase ^[3] .

HY-20558R

*D-(+)-Malic* acid (Standard)**	Structural Classification Microorganisms Ketones, Aldehydes, Acids Malus pumila Mill. Source classification Rosaceae Plants	Endogenous Metabolite
D-(+)-Malic acid (Standard) is the analytical standard of D-(+)-Malic acid. This product is intended for research and analytical applications. D-(+)-Malic acid (D-Malic acid), an active enantiomer of Malic acid, is a competitive inhibitor of L(--)malic acid transport .

HY-N0216BS

Benzoic-3,5 Acid-d2	Classification of Application Fields	Isotope-Labeled Compounds
Benzoic-3,5 Acid-d₂ is the deuterium labeled Benzoic-3,5 Acid[1].

HY-Y1069R

*(S)-Malic* acid (Standard)**	Structural Classification Human Gut Microbiota Metabolites Immune System Disorder Microorganisms Ketones, Aldehydes, Acids Source classification Disease markers Nervous System Disorder Endogenous metabolite	Endogenous Metabolite
(S)-Malic acid (Standard) is the analytical standard of (S)-Malic acid. This product is intended for research and analytical applications. (S)-Malic acid ((S)-2-Hydroxysuccinic acid) is a dicarboxylic acid in naturally occurring form, contributes to the pleasantly sour taste of fruits and is used as a food additive. In Vitro: It is showed that ME is essential for (S)-2-Hydroxysuccinic acid (L-malic acid) utilization in L. casei. Furthermore, deletion of either the gene encoding the histidine kinase or the response regulator of the TC system resulted in the loss of the ability to grow on (S)-2-Hydroxysuccinic acid, thus indicating that the cognate TC system regulates and is essential for the expression of ME. Transcriptional analyses shows that expression of maeE is induced in the presence of (S)-2-Hydroxysuccinic acid and repressed by glucose, whereas TC system expression is induced by (S)-2-Hydroxysuccinic acid and is not repressed by glucose .

Species:	Human (11) Bovine (2)
Tag:	GFP (3) His (12) Strep (5) Trx (1) Flag (7)
Source:	HEK293 (10) E. coli (3)

Cat. No.	Compare	Product Name	Species	Source

HY-P74650

	*PC4/SUB1 Protein, Human (His)* Activated RNA polymerase II transcriptional coactivator p15; PC4; p14; sub1; RPO2TC1	Human	E. coli
	The PC4/SUB1 protein acts as a multifunctional coactivator that cooperates with TAF to promote functional interactions between upstream activators and the general transcription machinery. Its role extends to the potential stability of multiprotein transcription complexes. PC4/SUB1 Protein, Human (His) is the recombinant human-derived PC4/SUB1 protein, expressed by E. coli , with N-His labeled tag. The total length of PC4/SUB1 Protein, Human (His) is 127 a.a., with molecular weight of ~19 kDa.

HY-P703334

	ABCF3 Protein, Human (HEK293, His, Strep, Flag) ATP-binding cassette sub-family F member 3; ABCF3; Homo sapiens; Human	Human	HEK293
	ABCF3 Protein, Human (HEK293, His, Strep, Flag) is the recombinant human-derived ABCF3, expressed by HEK293 , with Strep, His, Flag labeled tag. The total length of ABCF3 Protein, Human (HEK293, His, Strep, Flag) is 708 a.a.,

HY-P7621

	ABCB5 Protein, Human (Trx) rHuABCB5, N-Trx; ATP-binding cassette sub-family B member 5; P-glycoprotein ABCB5; ABCB5	Human	E. coli
	ABCB5, N-Trx Protein, Human is a plasma membrane-spanning protein that in humans is encoded by the ABCB5 gene. ABCB5 is an ABC transporter and P-glycoprotein family member principally expressed in physiological skin and human malignant melanoma.

HY-P703309

	ABCA6 Protein, Human (HEK293, His, Strep, Flag) ATP-binding cassette sub-family A member 6; ABCA6; Homo sapiens; Human; Translocase	Human	HEK293
	ABCA6 Protein, Human (HEK293, His, Strep, Flag) is the recombinant human-derived ABCA6, expressed by HEK293 , with Strep, His, Flag labeled tag. The total length of ABCA6 Protein, Human (HEK293, His, Strep, Flag) is 1616 a.a.,

HY-P72069

	ABCC1 Protein, Human (His) ABC 29; ABC29; ABCC 1; ABCC; Abcc1; ATP binding cassette sub family C CFTR/MRP; member 1; ATP binding cassette sub-family C member 1; ATP binding cassette subfamily C member 1; ATP binding cassette transporter variant ABCC1delta ex13; ATP binding cassette transporter variant ABCC1delta ex13&14; ATP binding cassette transporter variant ABCC1delta ex25; ATP binding cassette transporter variant ABCC1delta ex25&26; ATP binding cassette, sub-family C CFTR/MRP; , member 1; ATP-binding cassette sub-family C member 1; DKFZp686N04233; DKFZp781G125; GS X; GSX; Leukotriene C4; transporter; LTC4 transporter; MRP 1; MRP; MRP1; MRP1_HUMAN; Multidrug resistance associated protein 1; Multidrug resistance protein; Multidrug resistance-associated protein 1; Multiple drug resistance associated protein; Multiple drug resistance protein 1	Human	E. coli
	ABCC1, Human (His) is a multitasking ATP-binding cassette (ABC) transporter. ABCC1, Human plays a part in inflammatory and other immunological diseases, age-related macular degeneration, cardiovascular disease, and certain neurological disorders as well as tumor progression.

HY-P701354

	ABCC4 Protein, Human (HEK293, GFP, Strep, His) ABCC4; ATP-binding cassette sub-family C member 4; MRP/cMOAT-related ABC transporter; Multi-specific organic anion transporter B; MOAT-B; Multidrug resistance-associated protein 4	Human	HEK293
	ABCC4 Protein, an ATP-binding cassette (ABC) family member, actively transports endogenous compounds (cAMP, cGMP, bile acids) and xenobiotics from cells. Its versatility extends to glutathione conjugates (LTC4, LTB4) and drug metabolites, mediating cotransport of bile acids with reduced glutathione. ABCC4's function includes resistance to anticancer agents like methotrexate, highlighting its role in cellular communication and drug transport. ABCC4 Protein, Human (HEK293, GFP, Strep, His) is the recombinant human-derived ABCC4 protein, expressed by HEK293 , with C-10*His, C-GFP, C-Strep labeled tag. The total length of ABCC4 Protein, Human (HEK293, GFP, Strep, His) is 1325 a.a., .

HY-P701355

	bABCC1 Protein, Bovine (HEK293, GFP, Strep, His) ABCC1; Multidrug resistance-associated protein 1; ATP-binding cassette sub-family C member 1; Glutathione-S-conjugate-translocating ATPase ABCC1; Leukotriene C(4) transporter; LTC4 transporter	Bovine	HEK293
	The bABCC1 protein plays a key role in cellular physiology, mediating the ATP-dependent export of a variety of substrates, including drugs and organic anions. Notably, it confers resistance to anticancer drugs, actively reducing their intracellular accumulation. bABCC1 Protein, Bovine (HEK293, GFP, Strep, His) is the recombinant human-derived bABCC1 protein, expressed by HEK293 , with C-10*His, C-GFP, C-Strep labeled tag. The total length of bABCC1 Protein, Bovine (HEK293, GFP, Strep, His) is 1530 a.a., .

HY-P701356

	bABCC1 Protein, Bovine (HEK293, E1454Q, GFP, Strep, His) ABCC1; Multidrug resistance-associated protein 1; ATP-binding cassette sub-family C member 1; Glutathione-S-conjugate-translocating ATPase ABCC1; Leukotriene C(4) transporter; LTC4 transporter	Bovine	HEK293
	The bABCC1 protein plays a key role in cellular physiology, mediating the ATP-dependent export of a variety of substrates, including drugs and organic anions. Notably, it confers resistance to anticancer drugs, actively reducing their intracellular accumulation. bABCC1 Protein, Bovine (HEK293, E1454Q, GFP, Strep, His) is the recombinant human-derived bABCC1 protein, expressed by HEK293 , with C-10*His, C-GFP, C-Strep labeled tag and E1454Q mutation. The total length of bABCC1 Protein, Bovine (HEK293, E1454Q, GFP, Strep, His) is 1530 a.a., .

HY-P703304

	ABCB10 Protein, Human (HEK293, Flag, His, E659Q) ATP-binding cassette sub-family B member 10, mitochondrial; ABC-mitochondrial erythroid protein; ABC-me protein; ATP-binding cassette transporter 10; ABC transporter 10 protein; Mitochondrial ATP-binding cassette 2; M-ABC2; ABCB10; Homo sapiens; Human; ABC transporter 10 protein	Human	HEK293
	ABCB10 Protein, Human (HEK293, Flag, His, E659Q) is the recombinant human-derived ABCB10, expressed by HEK293 , with His, Flag labeled tag. ,

HY-P703305

	ABCB10 Protein, Human (HEK293, Flag, His, N229A) ATP-binding cassette sub-family B member 10, mitochondrial; ABC-mitochondrial erythroid protein; ABC-me protein; ATP-binding cassette transporter 10; ABC transporter 10 protein; Mitochondrial ATP-binding cassette 2; M-ABC2; ABCB10; Homo sapiens; Human; ABC transporter 10 protein	Human	HEK293
	ABCB10 Protein, Human (HEK293, Flag, His, N229A) is the recombinant human-derived ABCB10, expressed by HEK293 , with His, Flag labeled tag. ,

HY-P703306

	ABCB10 Protein, Human (HEK293, Flag, His, N407A) ATP-binding cassette sub-family B member 10, mitochondrial; ABC-mitochondrial erythroid protein; ABC-me protein; ATP-binding cassette transporter 10; ABC transporter 10 protein; Mitochondrial ATP-binding cassette 2; M-ABC2; ABCB10; Homo sapiens; Human; ABC transporter 10 protein	Human	HEK293
	ABCB10 Protein, Human (HEK293, Flag, His, N407A) is the recombinant human-derived ABCB10, expressed by HEK293 , with His, Flag labeled tag. ,

HY-P703307

	ABCB10 Protein, Human (HEK293, Flag, His, N229A, F398A) ATP-binding cassette sub-family B member 10, mitochondrial; ABC-mitochondrial erythroid protein; ABC-me protein; ATP-binding cassette transporter 10; ABC transporter 10 protein; Mitochondrial ATP-binding cassette 2; M-ABC2; ABCB10; Homo sapiens; Human; ABC transporter 10 protein	Human	HEK293
	ABCB10 Protein, Human (HEK293, Flag, His, N229A, F398A) is the recombinant human-derived ABCB10, expressed by HEK293 , with His, Flag labeled tag. ,

HY-P703308

	ABCB10 Protein, Human (HEK293, Flag, His, N229A, N407A) ATP-binding cassette sub-family B member 10, mitochondrial; ABC-mitochondrial erythroid protein; ABC-me protein; ATP-binding cassette transporter 10; ABC transporter 10 protein; Mitochondrial ATP-binding cassette 2; M-ABC2; ABCB10; Homo sapiens; Human; ABC transporter 10 protein	Human	HEK293
	ABCB10 Protein, Human (HEK293, Flag, His, N229A, N407A) is the recombinant human-derived ABCB10, expressed by HEK293 , with His, Flag labeled tag. ,

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Cat. No.
Species
Source
Tag
Accession
Gene ID
Molecular Weight
Purity
Endotoxin Level
Biological Activity
Appearance
Formulation
Storage & Stability
Shipping
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name	Chemical Structure

HY-Y1069S

*(S)-Malic* acid-d3**
(S)-Malic acid-d₃ is the deuterium labeled (S)-Malic acid. (S)-Malic acid ((S)-2-Hydroxysuccinic acid) is a dicarboxylic acid in naturally occurring form, contributes to the pleasantly sour taste of fruits and is used as a food additive[1][2].

HY-B0302AS

Etidronic acid-d3 disodium
Etidronic acid-d₃ (disodium) is the deuterium labeled Etidronic acid disodium[1].

HY-103395S

Methylmalonic acid-d3
Methylmalonic acid-d₃ is the deuterium labeled Methylmalonic acid. Methylmalonic acid (Methylmalonate) is an indicator of Vitamin B-12 deficiency in cancer[1][2].

HY-18569S

3-Indoleacetic acid-d5 1 Publications Verification
3-Indoleacetic acid-d₅ is the deuterium labeled 3-Indoleacetic acid. 3-Indoleacetic acid-d₅ can be used as internal standard for assay of IAA releases by alkaline hydrolysis of ester and amide conjugates .

HY-15027S

5-Aminosalicylic Acid-d3 hydrochloride
5-Aminosalicylic Acid-d₃ (hydrochloride) is the deuterium labeled 5-Aminosalicylic Acid. 5-Aminosalicylic acid (Mesalamine) hydrochloride acts as a specific PPARγ agonist and also inhibits p21-activated kinase 1 (PAK1) and NF-κB.

HY-Y1069S3

*(S)-Malic* acid-13C4**
(S)-Malic acid- ¹³C₄ is the ¹³C labeled S-Malic acid (HY-Y1069)[1].

HY-13777S1

Zoledronic acid-d3
Zoledronic acid-d3 is the deuterium labeled Zoledronic acid .

HY-N0156S

Oleanolic acid-d3
Oleanolic acid-d₃ is the deuterium labeled Oleanolic Acid[1]. Oleanolic acid (Caryophyllin) is a natural compound from plants with anti-tumor activities[2].

HY-75087S

(R)-Pyrrolidine-2-carboxylic acid-d3
(R)-Pyrrolidine-2-carboxylic acid-d₃ is the deuterium labeled (R)-pyrrolidine-2-carboxylic acid. (R)-pyrrolidine-2-carboxylic acid is an endogenous metabolite.

HY-W154267S

3-Aminoisobutyric acid-d3 hydrochloride
3-Aminoisobutyric acid-d₃ (hydrochloride) is the deuterium labeled DL-Histidine[1].

HY-W004282S1

Undecanoic acid-d3
Undecanoic acid-d₃ is the deuterium labeled Undecanoic acid. Undecanoic acid (Undecanoate) is a monocarboxylic acid with antimycotic property, which inhibits the production of exocellular keratinase, lipase and the biosynthesis of several phospholipids in T. rubrum[1].

HY-I0746S

3-Aminobenzoic acid-d4
3-Aminobenzoic acid-d₄ is the deuterium labeled 3-Aminobenzoic acid[1].

HY-15027S1

5-Aminosalicylic acid-d3
5-Aminosalicylic acid-d₃ is the deuterium labeled 5-Aminosalicylic Acid. 5-Aminosalicylic acid (Mesalamine) acts as a specific PPARγ agonist and also inhibits p21-activated kinase 1 (PAK1) and NF-κB[1][2][3][4].

HY-13318S

Oseltamivir acid-d3 Maximum Cited Publications 56 Publications Verification
Oseltamivir acid-d₃ is a deuterium labeled Oseltamivir acid. Oseltamivir acid, the active metabolite of Oseltamivir phosphate, is an orally bioavailable, potent and selective inhibitor of influenza virus neuraminidase (IC50=2 nM) with activity against both influenza A and B viruses[1][2].

HY-Y1311S

Malic acid-d3
Malic acid-d₃ is the deuterium labeled Malic acid. Malic acid (Hydroxybutanedioic acid) is a dicarboxylic acid that is naturally found in fruits such as apples and pears. It plays a role in many sour or tart foods[1][2].

HY-Y0084S

3,4,5-Trimethoxybenzoic acid-d3
3,4,5-Trimethoxybenzoic acid-d₃ is the deuterium labeled 3,4,5-Trimethoxybenzoic acid[1]. 3,4,5-Trimethoxybenzoic acid (Eudesmic acid;Trimethylgallic Acid) is a benzoic acid derivative. A building block in medicine and organic synthesis.

HY-158995S1

3-Epiglycyrrhetinic acid-d3
3-Epiglycyrrhetinic acid-d3 (3α-Glycyrrhetic acid-d3) is the deuterium-labeled 3-Epiglycyrrhetinic acid. 3-Epiglycyrrhetinic acid is a derivative of glycyrrhetic acid. Glycyrrhetic acid and its derivative are considered to have anti-inflammatory, anti-ulcer, and antiviral activities .

HY-10844S1

Pretomanid-d5
Pretomanid-d₅ is deuterated labeled Pretomanid (HY-10844). Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 μg/mL.

HY-18569S1

3-Indoleacetic acid-d4
3-Indoleacetic acid-d₄ (Indole-3-acetic acid-d₄; 3-IAA-d₄)is the deuterium labeled3-Indoleacetic acid(HY-18569) . 3-Indoleacetic acid (Indole-3-acetic acid) is the most common natural plant growth hormone of the auxin class. It can be added to cell culture medium to induce plant cell elongation and division .

HY-B0421S

Mycophenolic acid-d3
Mycophenolic acid-d₃ is deuterium labeled Mycophenolic acid, which is an an immunosuppresant agent and has potent anti-proliferative activity.

HY-113335S

Trihydroxycholestanoic acid-d3
Trihydroxycholestanoic acid-d₃ is the deuterium labeled Trihydroxycholestanoic acid[1].

HY-B1053S

Iotalamic acid-d3
Iotalamic acid-d₃ is the deuterium labeled Iotalamic acid[1].

HY-Y1088S3

Hydrocinnamic acid-d5
Hydrocinnamic acid-d₅ is the deuterium labeled Hydrocinnamic acid[1]. Hydrocinnamic acid is the major rhizospheric compound with known growth regulatory activities[2].

HY-15027S3

5-Aminosalicylic acid-d3 disodium
5-Aminosalicylic acid-d₃ disodium is deuterated labeled 5-Aminosalicylic Acid (HY-15027). 5-Aminosalicylic acid (Mesalamine) acts as a specific PPARγ agonist and also inhibits p21-activated kinase 1 (PAK1) and NF-κB.5-Aminosalicylic acid can inhibit the activity of osteopontin (OPN).

HY-Y1088S2

Hydrocinnamic acid-d9
Hydrocinnamic acid-d₉ is the deuterium labeled Hydrocinnamic acid[1]. Hydrocinnamic acid is the major rhizospheric compound with known growth regulatory activitie[2]s.

HY-113371AS

2-Methylcitric acid-d3 trisodium
2-Methylcitric acid-d₃ (Methylcitric acid-d₃) trisodium is deuterium-labeled 2-Methylcitric acid (trisodium) (HY-113371A) .

HY-N0184S

Glycyrrhizic acid-d3
Glycyrrhizic acid-d₃ (Glycyrrhizin-d₃) is deuterium labeled Glycyrrhizic acid. Glycyrrhizic acid is a triterpenoid saponinl, acting as a direct HMGB1 antagonist, with anti-tumor, anti-diabetic activities .

HY-N0384S4

Homovanillic acid-d3-1
Homovanillic acid-d3-1 (Vanilacetic acid-d3-1) is deuterated labeled Homovanillic acid (HY-N0384). Homovanillic acid is a dopamine metabolite associated with aromatic amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and adiponectin reductase deficiency .

HY-18569S3

3-Indoleacetic acid-d7
3-Indoleacetic acid-d₇ is the deuterium labeled 3-Indoleacetic acid[1]. 3-Indoleacetic acid (Indole-3-acetic acid) is the most common natural plant growth hormone of the auxin class. It can be added to cell culture medium to induce plant cell elongation and division .

HY-119695AS2

Simvastatin acid-d3 ammonium
Simvastatin acid-d₃ (Tenivastatin-d₃) ammonium is deuterium-labeled Simvastatin acid (ammonium) (HY-119695A) .

HY-Y1313S

3-Nitrobenzoic acid-d4
3-Nitrobenzoic acid-d₄ is the deuterium labeled 3-Nitrobenzoic acid[1].

HY-N0384S

Homovanillic acid-d3
Homovanillic acid-d₃ is the deuterium labeled Homovanillic acid. Homovanillic acid is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency.

HY-41417S1

Octanoic acid-d3
Octanoic acid-d₃ is the deuterium labeled Octanoic acid. Octanoic acid (Caprylic acid) is an oily liquid with a slightly unpleasant rancid taste and used commercially in the production of esters used in perfumery and also in the manufacture of dyes.

HY-158995S

3-Epiglycyrrhetinic acid-d2
3-Epiglycyrrhetinic acid-d2 (3α-Glycyrrhetic acid-d2) is the deuterium-labeled 3-Epiglycyrrhetinic acid. 3-Epiglycyrrhetinic acid is a derivative of glycyrrhetic acid. Glycyrrhetic acid and its derivative are considered to have anti-inflammatory, anti-ulcer, and antiviral activities .

HY-Y0957S

2,5-Difluorobenzoic acid-d3
2,5-Difluorobenzoic acid-d₃ is the deuterium labeled 2,5-Difluorobenzoic acid[1].

HY-107494S2

4-Oxoretinoic acid-d3
4-Oxoretinoic acid-d₃ is the deuterium labeled 4-Oxoretinoic acid[1].

HY-W004260S2

Arachidic acid-d3
Arachidic acid-d₃) is the deuterium labeled Arachidic acid. Arachidonic acid (Icosanoic acid), a long-chain fatty acid, is present in all mammalian cells, typically esterified to membrane phospholipids, and is one of the most abundant polyunsaturated fatty acids present in human tissue[1][2].

HY-N7057S1

Nonanoic acid-d3
Nonanoic acid-d₃ is the deuterium labeled Nonanoic acid. Nonanoic acid is a naturally-occurring saturated fatty acid with nine carbon atoms. Nonanoic acid significantly reduces bacterial translocation, enhances antibacterial activity, and remarkably increases the secretion of porcine β-defensins 1 (pBD-1) and pBD-2[1].

HY-121883S1

Lignoceric acid-d3
Lignoceric acid-d₃ is the deuterium labeled Lignoceric acid[1]. Lignoceric acid (Tetracosanoic acid) is a 24-carbon saturated (24:0) fatty acid, which is synthesized in the developing brain. Lignoceric acid is also a by-product of lignin production. Lignoceric acid can be used for Zellweger cerebro‐hepato‐renal syndrome and adrenoleukodystrophy research[2][3].

HY-W091636S

3,3'-Azanediyldipropionic acid-d8
3,3'-Azanediyldipropionic acid-d₈ is the deuterium labeled 3,3'-Azanediyldipropionic acid[1].

HY-101411S

4-Acetamidobutanoic acid-d3
4-Acetamidobutanoic acid-d3 is the deuterated analog of 4-Acetamidobutanoic acid (HY-101411). 4-Acetamidobutanoic acid (N-acetyl GABA), the main metabolite of GABA, exhibits antioxidant and antibacterial activities .

HY-76547S2

p-Toluic acid-d3
p-Toluic acid-d3 is the deuterium labeled p-Toluic acid[1]. p-Toluic acid (4-Methylbenzoic acid) is a substituted benzoic acid and can be used as an intermediate for the synthesis of para-aminomethylbenzoic acid (PAMBA), p-tolunitrile, etc.

HY-W018728S

3,5-Dimethylbenzoic acid-d9
3,5-Dimethylbenzoic acid-d₉ is the deuterium labeled 3,5-Dimethylbenzoic acid[1].

HY-B1689AS

Methantheline-d3 bromide
Methantheline-d₃ (bromide) is the deuterium labeled Methantheline bromide[1].

HY-78985S

Benzene-1,3,5-tricarboxylic acid-d3
Benzene-1,3,5-tricarboxylic acid-d₃ is the deuterium labeled Benzene-1,3,5-tricarboxylic acid[1].

HY-113371S

2-Methylcitric acid-d3

2-Methylcitric acid-d₃ is the deuterium labeled 2-Methylcitric acid. 2-Methylcitric acid (Methylcitric acid) is an endogenous metabolite in the 2-methylcitric acid cycle. 2-Methylcitric acid accumulates in methylmalonic and propionic acidemias and acts as a marker metabolite. 2-Methylcitric acid markedly inhibits ADP-stimulated and uncoupled respiration in mitochondria supported by glutamate[1].

HY-W014839S1

Cyclamic acid-d4 sodium
Cyclamic acid-d4 (sodium) is the deuterium labeled Cyclamic acid (sodium) .

HY-113323S

3-Methoxy-4-hydroxyphenylglycol-d3
3-Methoxy-4-hydroxyphenylglycol-d₃ is the deuterium labeled 3-Methoxy-4-hydroxyphenylglycol.

HY-17413S

Zidovudine-d3

Zidovudine-d₃ is the deuterium labeled Zidovudine. Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection. Zidovudine increases CRISPR/Cas9-mediated editing frequency. Zidovudine-d3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-B1773AS5

Sodium Propionate-d3
Sodium Propionate-d₃ is the deuterium labeled Sodium Propionate[1].

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P80527

	ABCB5 Antibody (YA836) ABCB5 P-gp; ATP binding cassette sub family B (MDR/TAP) member 5; P glycoprotein ABCB5	WB, ICC/IF	Human
	ABCB5 Antibody (YA836) is a non-conjugated and Mouse origined monoclonal antibody about 139 kDa, targeting to ABCB5 (8D2). It can be used for WB,ICC/IF assays with tag free, in the background of Human.

HY-P80772

	P Glycoprotein Antibody p-pg; PGP; ABCB1; MDR1; PGY1; Multidrug resistance protein 1; ATP-binding cassette sub-family B member 1; P-glycoprotein 1; CD antigen CD243	WB	Human
	P Glycoprotein Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 141 kDa, targeting to P Glycoprotein. It can be used for WB assays with tag free, in the background of Human.

HY-P81118

	MRP2 Antibody ABC30 antibody; abcC2 antibody; ATP binding cassette sub family C (CFTR/MRP) member 2 antibody; ATP binding cassette subfamily C member 2 antibody; ATP-binding cassette sub-family C member 2 antibody; Canalicular multidrug resistance protein antibody; Canalicular multispecific organic anion transporter 1 antibody; CMOAT antibody; CMOAT1 antibody; cMRP antibody; DJS antibody; KIAA1010 antibody; MRP 2 antibody; MRP2_HUMAN antibody; Multidrug resistance associated protein 2 antibody; Multidrug resistance-associated protein 2 antibody;	WB, ICC/IF, FC	Human
	MRP2/ABCC2 Antibody is an unconjugated, approximately 174 kDa, rabbit-derived, anti-MRP2/ABCC2 monoclonal antibody. MRP2/ABCC2 Antibody can be used for: WB, ICC/IF, FC expriments in human background without labeling.

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Cat. No.	Product Name		Classification

HY-12008S

Erlotinib-d6 hydrochloride CP-358774-d<sub>6sub> hydrochloride; NSC 718781-d<sub>6sub> hydrochloride; OSI-774-d<sub>6sub> hydrochloride		Alkynes
Erlotinib-d₆ (hydrochloride) a deuterium labeled Erlotinib Hydrochloride. Erlotinib Hydrochloride inhibits purified EGFR kinase with an IC50 of 2 nM[1]. Erlotinib-d6 (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-B0216S

Ethynyl Estradiol-d4 17α-Ethynylestradiol-d<sub>4sub>; Ethynylestradiol-d<sub>4sub>		Alkynes
Ethynyl Estradiol-d₄ is the deuterium labeled Ethynyl Estradiol. Ethynyl Estradiol (17α-Ethynylestradiol;Ethynylestradiol) is an orally bio-active estrogen used in almost all modern formulations of combined oral contraceptive pills. Ethynyl Estradiol-d4 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-G0018S

Norgestimate metabolite norelgestromin-d6 17-Deacetyl norgestimate-d<sub>6sub>; 17-Deacylnorgestimate-d<sub>6sub>		Alkynes
Norgestimate metabolite norelgestromin-d₆ is the deuterium labeled Norgestimate metabolite norelgestromin. Norelgestromin is a metabolite of Norgestimate, which is a progestin or synthetic progestogen. Norgestimate metabolite norelgestromin-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-17413S

Zidovudine-d3 Azidothymidine-d<sub>3sub>; AZT-d<sub>3sub>; ZDV-d<sub>3sub>		Azide
Zidovudine-d₃ is the deuterium labeled Zidovudine. Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection. Zidovudine increases CRISPR/Cas9-mediated editing frequency. Zidovudine-d3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-17413S1

Zidovudine-13C,d3 Azidothymidine-¹³C,d<sub>3sub>; AZT-¹³C,d<sub>3sub>; ZDV-¹³C,d<sub>3sub>		Azide
Zidovudine- ¹³C,d₃ is the ¹³C- and deuterium labeled Zidovudine. Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection. Zidovudine increases CRISPR/Cas9-mediated editing frequency. Zidovudine-13C,d3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-14605BS

Rasagiline-13C3 mesylate racemic AGN1135-¹³C<sub>3sub>; TVP1012-¹³C<sub>3sub> racemic		Alkynes
Rasagiline- ¹³C₃ (mesylate racemic) is a ¹³C-labeled Rasagiline mesylate racemic. Rasagiline mesylate racemic is a highly potent selective irreversible mitochondrial monoamine oxidase (MAO) inhibitor[1]. Rasagiline-13C3 (mesylate racemic) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-144162S

(Rac)-Selegiline-d5 hydrochloride (Rac)-Deprenyl-d<sub>5sub> hydrochloride; (±)-Selegiline-d<sub>5sub> hydrochloride; (±)-Deprenyl-d<sub>5sub> hydrochloride		Alkynes
(Rac)-Selegiline-d₅ (hydrochloride) is the deuterium labeled (Rac)-Selegiline hydrochloride[1].

HY-50896S

Erlotinib-d6 CP-358774-d<sub>6sub>; NSC 718781-d<sub>6sub>; OSI-774-d<sub>6sub>		Alkynes
Erlotinib-d₆ (CP-358774 D6) is a deuterium labeled Erlotinib (CP-358774). Erlotinib is a directly acting inhibitor EGFR tyrosine kinase inhibitor with an IC50 of 2 nM for human EGFR[1]. Erlotinib-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-B0110S

Gestodene-d6 SHB 331-d<sub>6sub>; WL 70-d<sub>6sub>		Alkynes
Gestodene-d₆is the deuterium labeled Gestodene. Gestodene(SHB 331) is a progestogen hormonal contraceptive[1][2]. Gestodene-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-50896S1

Erlotinib-13C6 CP-358774-¹³C<sub>6sub>; NSC 718781-¹³C<sub>6sub>; OSI-774-¹³C<sub>6sub>		Alkynes
Erlotinib- ¹³C₆ is a ¹³C-labeled Erlotinib. Erlotinib is a directly acting EGFR tyrosine kinase inhibitor, with an IC50 of 2 nM for human EGFR[1].

HY-12008S1

Erlotinib-13C6 hydrochloride CP-358774-¹³C<sub>6sub> hydrochloride; NSC 718781-¹³C<sub>6sub> hydrochloride; OSI-774-¹³C<sub>6sub> hydrochloride		Alkynes
Erlotinib- ¹³C₆ (hydrochloride) is the ¹³C labeled Erlotinib Hydrochloride[1]. Erlotinib Hydrochloride (CP-358774 Hydrochloride) inhibits purified EGFR kinase with an IC50 of 2 nM[2]. Erlotinib-13C6 (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-B0257S

Levonorgestrel-d8 D-Norgestrel-d<sub>8sub>		Alkynes
Levonorgestrel-d₈ is the deuterium labeled Levonorgestrel. Levonorgestrel is a synthetic progestogen used as an active ingredient in some hormonal contraceptives[1][2]. Levonorgestrel-d8 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-B0216S2

Ethynyl Estradiol-13C2 17α-Ethynylestradiol-¹³C<sub>2sub>; Ethynylestradiol-¹³C<sub>2sub>		Alkynes
Ethynyl Estradiol- ¹³C₂ is the ¹³C-labeled Ethynyl Estradiol. Ethynyl Estradiol-13C2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-B1710S

Norethindrone acetate-d8 19-Norethindrone acetate-d<sub>8sub>		Alkynes
Norethindrone acetate-d₈ is the deuterium labeled Norethindrone acetate. Norethindrone acetate is a female hormone used for the research of endometriosis[1]. Norethindrone acetate-d8 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-150544S

N-Desmethyl selegiline-d5 hydrochloride (-)-N-Desmethylselegiline-d<sub>5sub> hydrochloride		Alkynes
N-Desmethyl Selegiline-dd₅ hydrochloride is the deuterium labeled N-Desmethyl Selegiline hydrochloride[1]. N-Desmethyl Selegiline-d5 hydrochloride is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-167690

MK-6186		Alkynes
MK-6186 is a novel non-nucleoside reverse transcriptase inhibitor with sub-nanomolar activity against wild-type viruses and the two most common NNRTI-resistant RT mutants (K103N and Y181C). MK-6186 exhibits excellent antiviral activity against K103N and Y181C mutant viruses. When MK-6186 targets 12 common NNRTI-associated mutant viruses, only two relatively rare mutants (Y188L and V106I/Y188L) show high resistance, with FC values exceeding 100, while the FC values of the remaining viruses are all below 10. In addition, when MK-6186 faces 96 clinical virus isolates carrying NNRTI-resistant mutations, most (70%) viruses show more than 10-fold resistance to efavirenz (EFV), while only 29% of mutant viruses show more than 10-fold resistance to MK-6186 .

HY-W027544S1

(7-Methoxy-2-oxo-2H-chromen-4-yl)-acetic acid-d6 5-(Dimethyl-d6-amino)-N-(prop-2-ynyl)naphthalene-1-sulfonamide		Alkynes
(7-Methoxy-2-oxo-2H-chromen-4-yl)-acetic acid-d₆ is the deuterium labeled MCA[1]. MCA is a coumarin derivative. MCA quantitates platelet-activating factor by high-performance liquid chromatography with fluorescent detection. MCA can modify FRET peptide substrates for analyzing protease activities[2][3]. (7-Methoxy-2-oxo-2H-chromen-4-yl)-acetic acid-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Cat. No.	Product Name		Classification

HY-Y1069

*(S)-Malic* acid** 1 Publications Verification (S)-Hydroxybutanedioic acid; (S)-E 296; L-Malic acid		Flavoring Agents
(S)-Malic acid ((S)-2-Hydroxysuccinic acid) is a dicarboxylic acid in naturally occurring form, contributes to the pleasantly sour taste of fruits and is used as a food additive.

HY-RS13999

SUB1 Human Pre-designed siRNA Set A		siRNAs Pre-designed siRNA Sets
SUB1 Human Pre-designed siRNA Set A contains three designed siRNAs for SUB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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L-Malic acid-d<sub>3</sub>

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

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Isotope-Labeled Compounds

Antibodies

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