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CX<sub>3</sub>CR1<sup> </sup>

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By Targets:	5 alpha Reductase (1) 5-HT Receptor (1) ADC Cytotoxin (2) Adrenergic Receptor (3) AIM2 (1) Amino Acid Derivatives (2) Amyloid-β (3) Anaplastic lymphoma kinase (ALK) (1) Androgen Receptor (2) Antibiotic (34) Apical Sodium-Dependent Bile Acid Transporter (1) Apoptosis (69) Aryl Hydrocarbon Receptor (1) Autophagy (45) Bacterial (59) Bcl-2 Family (1) Beta-lactamase (1) Beta-secretase (1) Biochemical Assay Reagents (6) Calcium Channel (18) Carbonic Anhydrase (3) Casein Kinase (4) Caspase (1) Cathepsin (1) CCR (2) CD73 (1) CGRP Receptor (1) Checkpoint Kinase (Chk) (1) Cholinesterase (ChE) (1) Complement System (1) COX (9) CX3CR1 (4) CXCR (3) Cytochrome P450 (1) Disulfidptosis (1) DNA Methyltransferase (1) DNA/RNA Synthesis (53) Dopamine Receptor (2) Drug Metabolite (5) Dynamin (1) DYRK (1) E1/E2/E3 Enzyme (2) EAAT (1) EGFR (2) Endogenous Metabolite (391) Epigenetic Reader Domain (1) ERK (3) Estrogen Receptor/ERR (7) Eukaryotic Initiation Factor (eIF) (1) Fatty Acid Synthase (FASN) (2) Ferroptosis (15) Flavivirus (1) Fluorescent Dye (3) Fungal (5) FXR (2) G protein-coupled Bile Acid Receptor 1 (2) GABA Receptor (9) Gap Junction Protein (7) Glutathione Reductase (1) GlyT (1) GSK-3 (1) HBV (1) HCV (1) HDAC (1) Hexokinase (3) HIF/HIF Prolyl-Hydroxylase (6) Histamine Receptor (1) Histone Acetyltransferase (2) Histone Demethylase (2) Histone Methyltransferase (2) HIV (10) HIV Integrase (1) HIV Protease (1) HPV (2) HSP (1) HSV (9) IGF-1R (1) iGluR (16) IKK (2) Imidazoline Receptor (1) Influenza Virus (11) Interleukin Related (2) Isotope-Labeled Compounds (494) JAK (1) JNK (1) Keap1-Nrf2 (2) Ketohexokinase (2) Ligands for E3 Ligase (2) Liposome (2) Lipoxygenase (2) mAChR (1) MDM-2/p53 (1) Melanocortin Receptor (1) mGluR (10) Microtubule/Tubulin (2) Mitochondrial Metabolism (3) Mitophagy (5) MMP (1) Molecular Glues (3) Monoamine Oxidase (2) mTOR (1) Na+/K+ ATPase (2) nAChR (1) Neprilysin (2) Neurokinin Receptor (1) NF-κB (8) NO Synthase (11) NOD-like Receptor (NLR) (2) Nuclear Hormone Receptor 4A/NR4A (1) Nucleoside Antimetabolite/Analog (42) Opioid Receptor (1) Organoid (1) Orthopoxvirus (8) Oxidative Phosphorylation (1) P-glycoprotein (3) P2Y Receptor (3) p38 MAPK (1) PAK (2) Parasite (16) PARP (1) PD-1/PD-L1 (1) PGE synthase (1) Phosphatase (2) Phosphodiesterase (PDE) (1) Phospholipase (1) Pim (3) PKA (1) Potassium Channel (6) PPAR (2) Progesterone Receptor (4) Prostaglandin Receptor (2) PROTAC Linkers (2) Proteasome (1) RAD51 (2) RAR/RXR (1) Ras (2) Reactive Oxygen Species (27) RSV (3) SARS-CoV (6) Ser/Thr Protease (2) SGLT (1) Sirtuin (3) Small Interfering RNA (siRNA) (7) Sodium Channel (8) STAT (2) STING (2) TGF-beta/Smad (1) Thrombin (2) Thrombopoietin Receptor (2) Thymidylate Synthase (4) Thyroid Hormone Receptor (3) Toll-like Receptor (TLR) (1) Topoisomerase (3) TRP Channel (1) Tyrosinase (2) VD/VDR (2) VEGFR (2) Virus Protease (1) Wee1 (1) Xanthine Oxidase (2)
By Research Areas:	Cancer (239) Cardiovascular Disease (38) Endocrinology (27) Infection (92) Inflammation/Immunology (82) Metabolic Disease (180) Neurological Disease (97)
Click Chemistry:	Labeling and Fluorescence Imaging (2) Azide (1) Tetrazine (1) Alkynes (5)
Oligonucleotides:	Pre-designed siRNA Sets (7) siRNAs (7)

856

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
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Recombinant Proteins

699

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-15306S

Eltrombopag-13C4 1 Publications Verification SB-497115-<sup>13sup>C<sub>4sub>	Thrombopoietin Receptor Bacterial Apoptosis	Infection Cardiovascular Disease Cancer
Eltrombopag- ¹³C₄ (SB-497115- ¹³C₄) is ^{13 sup>C-labeled Z-Eltrombopag. Z-Eltrombopag is an orally active thrombopoietin-receptor non-peptide agonist with platelet-stimulating activity for the study of chronic immune thrombocytopenia. Eltrombopag also has strong inhibitory effects on multidrug-resistant Staphylococcus aureus (Staphylococcus aureus) and can induce apoptosis (apoptosis) in liver cancer cells ^[1] ^[3] .}

HY-N0898S

Catechin-13C3 (+)-Catechin-<sup>13sup>C<sub>3sub>; Cianidanol-<sup>13sup>C<sub>3sub>; Catechuic acid-<sup>13sup>C<sub>3sub>	COX Apoptosis Influenza Virus Endogenous Metabolite	Cancer
Catechin- ¹³C₃ is the ¹³C-labeled Catechin. Catechin ((+)-Catechin) inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM.

HY-D0184S2

2'-Deoxycytidine-15N3 Deoxycytidine-<sup>15sup>N<sub>3sub>; Cytosine deoxyriboside-<sup>15sup>N<sub>3sub>; Deoxyribose cytidine-<sup>15sup>N<sub>3sub>	Endogenous Metabolite	Others
2'-Deoxycytidine- ¹⁵N₃ is the ¹⁵N labeled 2'-Deoxycytidine[1]. 2'-Deoxycytidine, a deoxyribonucleoside, could inhibit biological effects of Bromodeoxyuridine (Brdu)[2].

HY-D0184S3

2'-Deoxycytidine-13C9,15N3 Deoxycytidine-<sup>13sup>C<sub>9sub>,<sup>15sup>N<sub>3sub>; Cytosine deoxyriboside-<sup>13sup>C<sub>9sub>,<sup>15sup>N<sub>3sub>; Deoxyribose cytidine-<sup>13sup>C<sub>9sub>,<sup>15sup>N<sub>3sub>	Isotope-Labeled Compounds Endogenous Metabolite	Others
2'-Deoxycytidine- ¹³C₉, ¹⁵N₃ (Deoxycytidine- ¹³C₉, ¹⁵N₃; Cytosine deoxyriboside- ¹³C₉, ¹⁵N₃; Deoxyribose cytidine- ¹³C₉, ¹⁵N₃) is ¹³C and ¹⁵N-labeled 2'-Deoxycytidine (HY-D0184). 2'-Deoxycytidine, a deoxyribonucleoside, could inhibit biological effects of Bromodeoxyuridine (Brdu).

HY-RS03131

CR1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
CR1 Human Pre-designed siRNA Set A contains three designed siRNAs for CR1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

CR1 Human Pre-designed siRNA Set A CR1 Human Pre-designed siRNA Set A

HY-RS03379

CX3CR1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
CX3CR1 Human Pre-designed siRNA Set A contains three designed siRNAs for CX3CR1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

CX3CR1 Human Pre-designed siRNA Set A CX3CR1 Human Pre-designed siRNA Set A

HY-RS03380

Cx3cr1 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Cx3cr1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cx3cr1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Cx3cr1 Mouse Pre-designed siRNA Set A Cx3cr1 Mouse Pre-designed siRNA Set A

HY-RS03381

Cx3cr1 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Cx3cr1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Cx3cr1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Cx3cr1 Rat Pre-designed siRNA Set A Cx3cr1 Rat Pre-designed siRNA Set A

HY-A0253S

Cefacetrile-13C3 Cephacetrile-<sup>13sup>C<sub>3sub>; Cephacetril-<sup>13sup>C<sub>3sub>	Antibiotic Bacterial Isotope-Labeled Compounds	Others
Cefacetrile- ¹³C₃ is the ¹³C₃ labeled Cefacetrile.

HY-B0139AS

Flucytosine-15N3 hydrochloride 5-Fluorocytosine-<sup>15sup>N<sub>3sub> hydrochloride; NSC 103805-<sup>15sup>N<sub>3sub> hydrochloride; Ro 2-9915-<sup>15sup>N<sub>3sub> hydrochloride	Isotope-Labeled Compounds	Others
Flucytosine- ¹⁵N₃ hydrochloride is ¹⁵N labeled Flucytosine.

HY-B0234S

Estrone-13C3 E1-<sup>13sup>C<sub>3sub>; Oestrone-<sup>13sup>C<sub>3sub>	Estrogen Receptor/ERR Endogenous Metabolite	Endocrinology Cancer
Estrone- ¹³C₃ is the ¹³C-labeled Estrone. Estrone (E1) is a natural estrogenic hormone. Estrone is the main representative of the endogenous estrogens and is produced by several tissues, especially adipose tissue. Estrone is the result of the process of aromatization of androstenedione that occurs in fat cells[1][2].

HY-40354S

Tofacitinib-13C3 Tasocitinib-<sup>13sup>C<sub>3sub>; CP-690550-<sup>13sup>C<sub>3sub>	JAK Apoptosis	Inflammation/Immunology Cancer
Tofacitinib- ¹³C₃ is the ¹³C-labeled Tofacitinib. Tofacitinib is an orally available JAK3/2/1 inhibitor with IC50s of 1, 20, and 112 nM, respectively.

HY-B1331S1

Cyromazine-13C3 Cyromazin-<sup>13sup>C<sub>3sub>; CGA-72662-<sup>13sup>C<sub>3sub>	Isotope-Labeled Compounds Endogenous Metabolite	Neurological Disease
Cyromazine- ¹³C₃ is the ¹³C₃ labeled Cyromazine. Cyromazine is a triazine insect growth regulator used as an insecticide and an acaricide. It is a cyclopropyl derivative of melamine. Cyromazine works by affecting the nervous system of the immature larval stages of certain insects.

HY-100196S1

Pyrroloquinoline quinone-13C3 sodium PQQ-<sup>13sup>C<sub>3sub> sodium; Methoxatin-<sup>13sup>C<sub>3sub> sodium	Endogenous Metabolite	Inflammation/Immunology
Pyrroloquinoline quinone-13C3 (sodium) is an isotope of Pyrroloquinoline quinone. Pyrroloquinoline quinone (PQQ), a redox co-factor, is an anionic, redox-cycling orthoquinone. Pyrroloquinoline quinone is isolated from cultures of methylotropic bacteria and tissues of mammals. Pyrroloquinoline quinone is an essential nutrient for mammals and is important for immune function ^[1].

HY-B1804S

Tricaprilin-13C3 Trioctanoin-<sup>13sup>C<sub>3sub>; Glyceryl trioctanoate-<sup>13sup>C<sub>3sub>	Isotope-Labeled Compounds Endogenous Metabolite	Neurological Disease
Tricaprilin-13C3 is a deuterated labeled Tricaprilin ^[1]. Tricaprilin (Trioctanoin) is used in study for patients with mild to moderate Alzheimer's disease and has a role as an anticonvulsant and a plant metabolite ^[3].

HY-W653853

Ritonavir-13C3 ABT 538-<sup>13sup>C<sub>3sub>; RTV-<sup>13sup>C<sub>3sub>	Isotope-Labeled Compounds Apoptosis SARS-CoV HIV Protease HIV	Cancer
Ritonavir- ¹³C₃ is ¹³C labeled Ritonavir. Ritonavir (ABT 538) is an inhibitor of HIV protease used to treat HIV infection and AIDS. Ritonavir is also a SARS-CoV 3CL ^pro inhibitor with an IC₅₀ of 1.61 μM ^[1].

HY-B0389S18

D-Glucose-13C3-1 Glucose-<sup>13sup>C<sub>3sub>-1; D-(+)-Glucose-<sup>13sup>C<sub>3sub>-1; Dextrose-<sup>13sup>C<sub>3sub>-1	Endogenous Metabolite	Metabolic Disease
D-Glucose- ¹³C₃-1 is the ¹³C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].

HY-B0389S9

D-Glucose-13C3-2 Glucose-<sup>13sup>C<sub>3sub>-2; D-(+)-Glucose-<sup>13sup>C<sub>3sub>-2; Dextrose-<sup>13sup>C<sub>3sub>-2	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
D-Glucose- ¹³C₃-2 is the ¹³C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].

HY-W654126

Cytarabine-13C3 Cytosine β-D-arabinofuranoside--<sup>13sup>C<sub>3sub>; Cytosine Arabinoside--<sup>13sup>C<sub>3sub>; Ara-C-<sup>13sup>C<sub>3sub>	Isotope-Labeled Compounds	Others
Cytarabine- ¹³C₃ (Cytosine β-D-arabinofuranoside- ¹³C₃) is ¹³C labeled Cytarabine ^[1].

HY-N0650S

L-Serine-13C3 (-)-Serine-<sup>13sup>C<sub>3sub>; (S)-Serine-<sup>13sup>C<sub>3sub>	Endogenous Metabolite	Cancer
L-Serine- ¹³C₃ is the ¹³C-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-B0495S4

Lamotrigine-13C3 LTG-<sup>13sup>C<sub>3sub>; BW430C-<sup>13sup>C<sub>3sub>	Sodium Channel Autophagy	Neurological Disease
Lamotrigine- ¹³C₃ is the ¹³C-labeled Lamotrigine. Lamotrigine (BW430C) is a potent and orally active anticonvulsant or antiepileptic agent. Lamotrigine selectively blocks voltage-gated Na+ channels, stabilizing presynaptic neuronal membranes and inhibiting glutamate release. Lamotrigine can be used for the research of epilepsy, focal seizure, et al[1][2].

HY-Y0219S

1,2,4-Triazole-13C2,15N3 s-Triazole<sup>13sup>C<sub>2sub>,<sup>15sup>N<sub>3sub>; Pyrrodiazole<sup>13sup>C<sub>2sub>,<sup>15sup>N<sub>3sub>	Isotope-Labeled Compounds	Others
NSC 83128- ¹³C₂, ¹⁵N₃ is the ¹³C and ¹⁵N labeled NSC 83128[1].

HY-N0680S3

Thiamine-13C3 hydrochloride Thiamine chloride-<sup>13sup>C<sub>3sub> hydrochloride; Vitamin B1-<sup>13sup>C<sub>3sub> hydrochloride	Isotope-Labeled Compounds Endogenous Metabolite Apoptosis HBV	Neurological Disease
Thiamine- ¹³C₃ (hydrochloride) is the ¹³C-labeled Thiamine (hydrochloride). Thiamine hydrochloride (Thiamine chloride hydrochloride) is an essential micronutrient needed as a cofactor for many central metabolic enzymes.

HY-14605S

Rasagiline-13C3 mesylate (R)-AGN1135-<sup>13sup>C<sub>3sub> mesylate; TVP1012-<sup>13sup>C<sub>3sub> mesylate	Isotope-Labeled Compounds	Others
Rasagiline- ¹³C₃ ((R)-AGN1135- ¹³C₃; TVP1012- ¹³C₃) mesylateis the deuterium labeledRasagiline (mesylate)(HY-14605) ^[1]. Rasagiline (R-AGN1135) mesylate is a highly potent selective irreversible mitochondrial monoamine oxidase (MAO) inhibitor with IC₅₀s of 4.43?nM and 412?nM for rat brain MAO B and A activity, respectively .

HY-W700491

AalphaC-15N3 2-Amino-α-carboline-<sup>15sup>N<sub>3sub>; AαC-<sup>15sup>N<sub>3sub>	Isotope-Labeled Compounds Endogenous Metabolite	Cancer
AalphaC- ¹⁵N₃ (2-Amino-α-carboline- ¹⁵N₃) is ¹⁵N labeled AalphaC. AalphaC (AαC) is a potential carcinogen with carcinogenic activity. AalphaC is an important biomarker in tobacco smoke and is associated with tobacco smoke exposure. Urinary concentrations of AalphaC are significantly higher in dedicated smokers than in non-smokers, indicating its importance in monitoring tobacco exposure. AalphaC levels increase significantly with increasing serum nicotine levels, indicating its close relationship with tobacco use. In addition, consuming high-temperature cooked beef significantly increases the amount of AalphaC in urine, while consuming vegetables is associated with a decrease in AalphaC concentrations. Smoking half a pack of cigarettes is associated with a significant increase in the amount of AalphaC, which further confirms the biological activity of AalphaC and its association with dietary habits ^[1] .

HY-Y0921S3

(±)-1,2-Propanediol-13C3 1,2-(RS)-Propanediol-<sup>13sup>C<sub>3sub>; 1,2-Propylene glycol-<sup>13sup>C<sub>3sub>; Propylene glycol-<sup>13sup>C<sub>3sub>	Endogenous Metabolite Isotope-Labeled Compounds	Neurological Disease
(±)-1,2-Propanediol- ¹³C₃ is ¹³C labeled (±)-1,2-Propanediol (HY-Y0921). (±)-1, 2-propanediol (1,2-(RS)-Propanediol) is an aliphatic alcohol that is often used as an excipient in many active molecular preparations to increase the solubility and stability of the active molecule. (±)-1, 2-propanediol can affect the neurobehavior of zebrafish ^[1] .

HY-B0150S1

Nicotinamide-15N,13C3 Niacinamide-<sup>15sup>N,<sup>13sup>C<sub>3sub>; Nicotinic acid amide-<sup>15sup>N,<sup>13sup>C<sub>3sub>	Endogenous Metabolite Sirtuin	Neurological Disease Cancer
Nicotinamide- ¹⁵N, ¹³C₃ is the ¹³C-labeled and ¹⁵N-labeled Nicotinamide. Nicotinamide is a form of vitamin B3 that plays essential roles in cell physiology through facilitating NAD+ redox homeostasis and providing NAD+ as a substrate to a class of enzymes that catalyze non-redox reactions. Nicotinamide is an inhibitor of SIRT1.

HY-14605BS

Rasagiline-13C3 mesylate racemic AGN1135-<sup>13sup>C<sub>3sub>; TVP1012-<sup>13sup>C<sub>3sub> racemic	Isotope-Labeled Compounds Monoamine Oxidase	Neurological Disease
Rasagiline- ¹³C₃ (mesylate racemic) is a ¹³C-labeled Rasagiline mesylate racemic. Rasagiline mesylate racemic is a highly potent selective irreversible mitochondrial monoamine oxidase (MAO) inhibitor[1]. Rasagiline-13C3 (mesylate racemic) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-B0891S1

17α-Hydroxyprogesterone-13C3 17-Hydroxyprogesterone-<sup>13sup>C<sub>3sub>; 17-OHP-<sup>13sup>C<sub>3sub>	Progesterone Receptor Endogenous Metabolite	Others
17α-Hydroxyprogesterone- ¹³C₃ is the ¹³C-labeled 17α-Hydroxyprogesterone. 17α-Hydroxyprogesterone (17-Hydroxyprogesterone) is an endogenous progestogen as well as chemical intermediate in the biosynthesis of other steroid hormones, including the corticosteroids and the androgens and the estrogens.

HY-N0086S3

N6-Methyladenosine-13C3 6-Methyladenosine-<sup>13sup>C<sub>3sub>; N-Methyladenosine-<sup>13sup>C<sub>3sub>	Isotope-Labeled Compounds Influenza Virus Endogenous Metabolite	Infection
N6-Methyladenosine- ¹³C₃ (6-Methyladenosine- ¹³C₃) is ¹³C-labeled N6-Methyladenosine (HY-N0086). N6-Methyladenosine is the most prevalent internal (non-cap) modification present in the messenger RNA (mRNA) of all higher eukaryotes. N6-Methyladenosine can modifies viral RNAs and has antiviral activities ^[1] ^[3].

HY-W777148

Anagrelide-13C3 BL 4162A-<sup>13sup>C<sub>3sub>; BMY 26538-01-<sup>13sup>C<sub>3sub>	Isotope-Labeled Compounds	Others
Anagrelide- ¹³C₃ (BL 4162A- ¹³C₃) is ¹³C labeled Anagrelide ^[1].

HY-B0178AS

Guanidine-13C,15N3 hydrochloride Guanidinium-<sup>13sup>C,<sup>15sup>N<sub>3sub> (chloride); Aminoformamidine-<sup>13sup>C,<sup>15sup>N<sub>3sub> (hydrochloride)	Endogenous Metabolite	Metabolic Disease
Guanidine- ¹³C, ¹⁵N₃ (hydrochloride)is the ¹³C-labeled and ¹⁵N-labeled Guanidine hydrochloride. Guanidine hydrochloride (Guanidinium chloride) a strong chaotrope, is also a strong denaturant of proteins[1][2].

HY-N0650S5

L-Serine-13C3,15N (-)-Serine-<sup>13sup>C<sub>3sub>,<sup>15sup>N; (S)-Serine-<sup>13sup>C<sub>3sub>,<sup>15sup>N	Endogenous Metabolite	Cancer
L-Serine- ¹³C₃, ¹⁵N is the ¹³C- and ¹⁵N-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-P2969

Complement factor I	Endogenous Metabolite	Metabolic Disease
Complement factor I is a serine protease that downregulates complement activity in the fluid phase and/or on cell surfaces in conjunction with one of its cofactors, factor H (FH), complement receptor 1 (CR1/CD35), C4 binding protein (C4BP) or membrane cofactor protein (MCP/CD46) ^[1].

HY-113008AS

cis-Urocanic acid-13C3 (Z)-Urocanic acid-<sup>13sup>C<sub>3sub>; cis-UCA-<sup>13sup>C<sub>3sub>	Isotope-Labeled Compounds 5-HT Receptor	Inflammation/Immunology
cis-Urocanic acid- ¹³C₃ is the ¹³C-labeled cis-Urocanic acid. cis-Urocanic acid is a 5-HT2A receptor agonist. cis-Urocanic acid binds to 5-HT receptor with relatively high affinity (Kd=4.6 nM). cis-Urocanic acid is an immune modulator that induces immunosuppression by binding to the 5-HT2A receptor[1].

HY-B1342S3

Vitamin A-13C3 Vitamin A1-<sup>13sup>C<sub>3sub>; all-trans-Retinol-<sup>13sup>C<sub>3sub>	Isotope-Labeled Compounds	Others
Vitamin A- ¹³C₃ (Vitamin A1- ¹³C₃; all-trans-Retinol- ¹³C₃) is a ¹³C-labeled Vitamin A/Vitamin A (HY-B1342). Vitamin A is an endogenous metabolite.

HY-B0158S5

Cytidine-13C9,15N3 Cytosine β-D-riboside-<sup>13sup>C<sub>9sub>,<sup>15sup>N<sub>3sub>; Cytosine-1-β-D-ribofuranoside-<sup>13sup>C<sub>9sub>,<sup>15sup>N<sub>3sub>	Nucleoside Antimetabolite/Analog Endogenous Metabolite	Neurological Disease
Cytidine- ¹³C₉, ¹⁵N₃ is the ¹³C and ¹⁵N labeled Cytidine[1]. Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catecholamine synthesis, and mitochondrial function[2][3][4].

HY-W009162S5

Cytidine 5′-monophosphate-13C9,15N3 dilithium 5'-Cytidylic acid-<sup>13sup>C<sub>9sub>,<sup>15sup>N<sub>3sub> dilithium; 5'-CMP-<sup>13sup>C<sub>9sub>,<sup>15sup>N<sub>3sub> dilithium	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
Cytidine 5′-monophosphate- ¹³C₉, ¹⁵N₃ (5'-Cytidylic acid- ¹³C₉, ¹⁵N₃ dilithium; 5'-CMP- ¹³C₉, ¹⁵N₃) dilithium is ¹³C and ¹⁵N-labeled Cytidine 5'-monophosphate (HY-W009162). Cytidine 5'-monophosphate (5'-Cytidylic acid) is a nucleotide which is used as a monomer in RNA. Cytidine 5'-monophosphate consists of the nucleobase cytosine, the pentose sugar ribose, and the phosphate group.

HY-101400S2

Deoxycytidine triphosphate-13C9,15N3 dilithium dCTP-<sup>13sup>C<sub>9sub>,<sup>15sup>N<sub>3sub> dilithium; 2′-Deoxycytidine-5′-triphosphate-<sup>13sup>C<sub>9sub>,<sup>15sup>N<sub>3sub> dilithium	Isotope-Labeled Compounds Nucleoside Antimetabolite/Analog DNA/RNA Synthesis Endogenous Metabolite	Metabolic Disease
Deoxycytidine triphosphate- ¹³C₉, ¹⁵N₃ (dCTP- ¹³C₉, ¹⁵N₃ dilithium; 2′-Deoxycytidine-5′-triphosphate- ¹³C₉, ¹⁵N₃) dilithium is ¹³C and ¹⁵N-labeled Deoxycytidine triphosphate (HY-101400). Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.

HY-N0610AS2

Cinnamic acid-13C3 3-PhenylaCRylic acid-<sup>13sup>C<sub>3sub>; β-PhenylaCRylic acid-<sup>13sup>C<sub>3sub>	Isotope-Labeled Compounds Endogenous Metabolite	Cancer
Cinnamic acid- ¹³C₃ (3-Phenylacrylic acid- ¹³C₃) is the ¹³C labeled Cinnamic acid (HY-N0610A). Cinnamic acid has potential use in cancer intervention, with IC₅₀s of 1-4.5 mM in glioblastoma, melanoma, prostate and lung carcinoma cells ^[1] .

HY-18569S4

3-Indoleacetic acid-13C6 Indole-3-acetic acid-<sup>13sup>C<sub>6sub>; 3-IAA-<sup>13sup>C<sub>6sub>	Endogenous Metabolite Molecular Glues	Others
3-Indoleacetic acid- ¹³C₆ is the ¹³C labeled 3-Indoleacetic acid[1]. 3-Indoleacetic acid (Indole-3-acetic acid) is the most common natural plant growth hormone of the auxin class. It can be added to cell culture medium to induce plant cell elongation and division ^[1].

HY-N0230S

β-Alanine-13C3,15N 2-Carboxyethylamine-<sup>13sup>C<sub>3sub>,<sup>15sup>N; 3-Aminopropanoic acid-<sup>13sup>C<sub>3sub>,<sup>15sup>N	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
β-Alanine- ¹³C₃, ¹⁵N is the ¹³C- and ¹⁵N-labeled β-Alanine. β-Alanine is a non-essential amino acid that is shown to be metabolized into carnosine, which functions as an intracellular buffer.

HY-125818S6

Cytidine-5'-triphosphate-15N3 dilithium Cytidine triphosphate-<sup>15sup>N<sub>3sub> dilithium; 5'-CTP-<sup>15sup>N<sub>3sub> dilithium	Isotope-Labeled Compounds DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Endogenous Metabolite	Infection Cancer
Cytidine-5'-triphosphate- ¹⁵N₃ (Cytidine triphosphate- ¹⁵N₃ dilithium; 5'-CTP- ¹⁵N₃) dilithium is ¹⁵N labeled Cytidine-5'-triphosphate (HY-125818). Cytidine 5′-triphosphate (Cytidine triphosphate; 5'-CTP) is a nucleoside triphosphate and serves as a building block for nucleotides and nucleic acids, lipid biosynthesis. Cytidine triphosphate synthase can catalyze the formation of cytidine 5′-triphosphate from uridine 5′-triphosphate (UTP). Cytidine 5′-triphosphate is an essential biomolecule?in the de novo?pyrimidine biosynthetic pathway in?T. gondii.

HY-101400S3

Deoxycytidine triphosphate-15N3 dilithium dCTP-<sup>15sup>N<sub>3sub> dilithium; 2′-Deoxycytidine-5′-triphosphate-<sup>15sup>N<sub>3sub> dilithium	Isotope-Labeled Compounds Nucleoside Antimetabolite/Analog DNA/RNA Synthesis Endogenous Metabolite	Metabolic Disease
Deoxycytidine triphosphate- ¹⁵N₃ (dCTP- ¹⁵N₃ dilithium; 2′-Deoxycytidine-5′-triphosphate- ¹⁵N₃) dilithium is ¹⁵N labeled Deoxycytidine triphosphate (HY-101400). Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.

HY-B1204S2

Histamine-13C5, 15N3 Ergamine-<sup>13sup>C<sub>5sub>, <sup>15sup>N<sub>3sub>	Isotope-Labeled Compounds Histamine Receptor Endogenous Metabolite	Neurological Disease Endocrinology Cancer
Histamine- ¹³C₅, ¹⁵N₃ (Ergamine- ¹³C₅, ¹⁵N₃) is the ¹³C and ¹⁵N labeled isotope of Histamine (HY-B1204). Histamine is an organic nitrogen compound that participates in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter ^[1].

HY-15129S

O-Phospho-L-serine-13C3,15N L-Serine O-phosphate-<sup>13sup>C<sub>3sub>,<sup>15sup>N; L-SOP-<sup>13sup>C<sub>3sub>,<sup>15sup>N	mGluR Endogenous Metabolite	Neurological Disease
O-Phospho-L-serine- ¹³C₃, ¹⁵N is the ¹³C- and ¹⁵N-labeled O-Phospho-L-serine. O-Phospho-L-serine is the immediate precursor to L-serine in the serine synthesis pathway, and an agonist at the group III mGluR receptors (mGluR4, mGluR6, mGluR7, and mGluR8); O-Phospho-L-serine also acts as a weak antagonist for mGluR1 and a potent antagonist for mGluR2[1].

HY-B0412S3

Estriol-13C3 Oestriol-<sup>13sup>C<sub>3sub>	Estrogen Receptor/ERR Endogenous Metabolite	Cancer
Estriol- ¹³C₃ is the ¹³C-labeled Estriol. Estriol is an antagonist of the G-protein coupled estrogen receptor in estrogen receptor-negative breast cancer cells.

HY-B1659S5

Glycerol-13C3 Glycerin-<sup>13sup>C<sub>3sub>	Endogenous Metabolite	Cancer
Glycerol- ¹³C₃ is the ¹³C labeled Glycerol[1]. Glycerol is used in sample preparation and gel formation for polyacrylamide gel electrophoresis[2][3][4].

HY-N0136S1

(±)-Taxifolin-13C3 (±)-Dihydroquercetin-<sup>13sup>C<sub>3sub>	Autophagy Tyrosinase	Inflammation/Immunology
(±)-Taxifolin-13C3 ((±)-Dihydroquercetin-13C3) is a derivative of (±)-Taxifolin, labeled with 13C3. (±)-Taxifolin is the racemate of Taxifolin. Taxifolin exhibits important anti-tyrosinase activity. Taxifolin exhibits significant inhibitory activity against collagenase with an IC₅₀ value of 193.3 μM ^[1]. Taxifolin is an important natural compound with antifibrotic activity. Taxifolin is a free radical scavenger with antioxidant capacity .

HY-B0111RS

Drospirenone-13C3 Dihydrospirorenone-<sup>13sup>C<sub>3sub>	Isotope-Labeled Compounds	Endocrinology
Drospirenone- ¹³C₃ is ¹³C labeled Drospirenone. Drospirenone (Dihydrospirorenone) is a synthetic progesterone that is an analog of Spironolactone ^[1].

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W074890

Palmitoylglycine N-palmitoyl glycine	Human Gut Microbiota Metabolites Microorganisms Neurological Disease Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Calcium Channel NO Synthase
Palmitoylglycine (N-palmitoyl glycine), an endogenous lipid that acts as a modulator of calcium influx and nitric oxide () production in sensory neurons. Palmitoylglycine is linked to an increased risk of Background Brugada syndrome (BrS) and interacts with BrS-associated proteins, demonstrating moderate binding affinities for DCC, CR1, CTSB, NAAA, DEFB1, EPHA1, IGF1/IGFBP3/ALS, and LTA ^[1] ^[3].

HY-125833

Alpha-Naphthoflavone 5+ Cited Publications	Flavonoids Flavones Source classification Indigofera heterantha Wall. ex Brand. Plants Compositae Disease Research Fields Cancer	Cytochrome P450 Aryl Hydrocarbon Receptor Apoptosis
Alpha-Naphthoflavone is an orally active flavonoid that is a potent, competitive inhibitor of aromatase< b>aromatase. < b > IC < sub > 50 < / sub > < / b > and < b > K < sub > I < / sub > < / b > value were 0.5 and 0.2 microns. Alpha-Naphthoflavone can inhibit cell proliferation and induce apoptosis ^[1] ^[3] .

HY-N3872

Ethyl β-D-glucopyranoside	Scabiosa stellata L. Structural Classification Natural Products Caprifoliaceae Source classification Plants	Others
Ethyl β-D-glucopyranoside (compound 10) is a kind of phenolic compound. Ethyl β-D-glucopyranoside can be isolated from ethanolic extract of Scabiosa stellata LS.

HY-N3980

Guaiol Champacol; Guaiac alcohol	Infection Structural Classification Natural Products Classification of Application Fields Source classification Distemonanthus benthamianus Baill. Plants Compositae Disease Research Fields	Autophagy RAD51
Guaiol is a sesquiterpenoid alcohol with oral activity found in various traditional Chinese medicines, exhibiting biological activities such as anti-proliferative, autophagy-promoting, insecticidal, anti-anxiety, anti-inflammatory, diuretic, and blood pressure-lowering effects. Guaiol induces apoptosis in non-small cell lung cancer cells by regulating the stability of RAD51 through autophagy modulation. Guaiol can also act directly on parasites, inhibiting their growth by affecting the kinetoplast, mitochondrial matrix and plasma membrane of the promastigotes. Guaiol kills amastigotes at an IC₅₀ of 0.01 µg/mL. Guaiol can be used in research related to cancer, infections, cardiovascular diseases, and inflammatory conditions ^[1] ^[3] ^{[4]sup .}

HY-N12231

Carbazomycin B	Structural Classification Monophenols Microorganisms Source classification Phenols	Antibiotic Bacterial Lipoxygenase
Carbazomycin B is a bacterial metabolite and can be isolated from Streptomyces. Carbazomycin B is an antifungal and antibacterial agent. Carbazomycin B inhibits 5-lipoxygenase (5-LO) activity in extract from RBL-1 cell with the IC₅₀ Of 1.5 µM ^[1]sup>[2]sup>[3]sup>[4].

HY-N11122

7-[α-L-Arabinopyranosyl-(1→6)-β-D-glucopyranosyloxy]cuminol	Structural Classification Natural Products Rhodiola rosea Linn. Source classification Crassulaceae Plants	Others
7-[α-L-Arabinopyranosyl-(1→6)-β-D-glucopyranosyloxy]cuminol is a cuminol glycoside. 7-[α-L-Arabinopyranosyl-(1→6)-β-D-glucopyranosyloxy]cuminol can be isolated from Rhodiola rosea sup>[1].

HY-N12110

SMU-CX1	Apocynaceae Structural Classification Alkaloids Other Alkaloids Source classification Plants	Toll-like Receptor (TLR) SARS-CoV
SMU-CX1 is a specific TLR3 inhibitor (IC₅₀: 0.11 μM) with IC₅₀ ranging from 0.14-0.33 μM against multiple influenza A virus subtypes. SMU-CX1 inhibits the viral PB2 and NP proteins with an IC₅₀ of 0.43 μM for SARS-CoV-2 activity. SMU-CX1 also inhibits inflammatory factors in host cells, including IFN-β, IP-10, and CCL-5 ^[1].

HY-N8824

Maackiaflavanone	Structural Classification Flavonoids Leguminosae Flavonones Source classification Maackia amurensis Rupr. et Maxim. Plants	Others
Maackiaflavanone (compound 4) is a kind of prenylated flavanone. Maackia can be isolated from M. amurensi.

HY-N8859

Isoiridogermanal 16-Hydroxyiridal	Structural Classification Natural Products Source classification Lridaceae Plants	Others
Isoiridogermanal can be isolated from the extract of rhizomes of Iris tectorum Maxim. Isoiridogermanal is cytotoxic with IC50 values of 11 μM and 23 μM against MCF-7 and C32 cell lines.

HY-N11799

Neochilenin 3-O-Methylquercetin 4′-O-glucoside	Structural Classification Flavonoids Source classification Plants Compositae Other Flavonoids	Others
Neochilenin (3-O-Methylquercetin 4 '-O-glucoside) is a glycoside of 3-O-methylquercetin, which can be isolated from the sub-family Cereoideae (Cactaceae). ^[1].

HY-N8930

Eupatorin-5-methyl ether	Structural Classification Galinsoga parviflora Cav. Flavonoids Flavones Labiatae Source classification Plants	Others
Eupatorin-5-methyl ether (TMF) can be isolated from Orthosiphon stamineus. Eupatorin-5-methyl ether is a kind of flavonoid compound. Eupatorin-5-methyl ether inhibits NO production (IC50 5.5 μM).

HY-W011474

Geranylgeraniol	Structural Classification Natural Products Microorganisms	NF-κB
Geranylgeraniol is an orally acitve vitamin K₂ sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model ^[1] ^[3] .

HY-N3980R

Guaiol (Standard)	Structural Classification Natural Products Source classification Distemonanthus benthamianus Baill. Plants Compositae	Autophagy RAD51
Guaiol (Standard) is the analytical standard of Guaiol. This product is intended for research and analytical applications. Guaiol is a sesquiterpenoid alcohol with oral activity found in various traditional Chinese medicines, exhibiting biological activities such as anti-proliferative, autophagy-promoting, insecticidal, anti-anxiety, anti-inflammatory, diuretic, and blood pressure-lowering effects. Guaiol induces apoptosis in non-small cell lung cancer cells by regulating the stability of RAD51 through autophagy modulation. Guaiol can also act directly on parasites, inhibiting their growth by affecting the kinetoplast, mitochondrial matrix and plasma membrane of the promastigotes. Guaiol kills amastigotes at an IC50 of 0.01 µg/mL. Guaiol can be used in research related to cancer, infections, cardiovascular diseases, and inflammatory conditions ^[1] ^[3][4] .

HY-P2274

Argifin	Infection Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields	Parasite
Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms, with IC₅₀s of 0.025 μM, 6.4 μM , 1.1 μM and 4.5 μM for SmChiA (Serratia marcescens chitinaese A), SmChiB, Aspergillus fumigatus chitinase B1 and human chitotriosidase, respectively ^[1].

HY-N10192

Aculene D	Infection Microorganisms Classification of Application Fields Terpenoids Sesquiterpenes Source classification Disease Research Fields	Endogenous Metabolite Bacterial
Aculene D, a fungal metabolite, shows quorum sensing (QS) inhibitory activity against Chromobacterium violaceum CV026, and could significantly reduce violacein production in N-hexanoyl-l-homoserine lactone (C6-HSL) induced C. violaceum CV026 cultures at sub-inhibitory concentrations ^[1].

HY-W011474R

Geranylgeraniol (Standard)	Structural Classification Natural Products Microorganisms	NF-κB
Geranylgeraniol (Standard) is the analytical standard of Geranylgeraniol. This product is intended for research and analytical applications. Geranylgeraniol is an orally acitve vitamin K2 sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model ^[1] ^[3][4].

HY-N0662

Amentoflavone 5+ Cited Publications Didemethyl-ginkgetin	Structural Classification Flavonoids Classification of Application Fields Source classification Phenols Polyphenols Selaginellaceae Plants Biflavones Selaginella tamariscina (P. Beauv.) Spring Disease Research Fields Cancer	Reactive Oxygen Species Apoptosis Bacterial Fungal RSV GABA Receptor
Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active GABA(A) negative modulator. Amentoflavone also shows anti-inflammatory, antioxidative, anti-viral, anti-tumor, anti-radiation, anti-fungal, antibacterial activity. Amentoflavone induces apoptosis and cell cycle arrest at sub-G1 phase ^[1] ^[3] .

HY-N0662R

Amentoflavone (Standard)	Structural Classification Flavonoids Source classification Phenols Polyphenols Selaginellaceae Plants Biflavones Selaginella tamariscina (P. Beauv.) Spring	Reactive Oxygen Species Apoptosis Bacterial Fungal RSV GABA Receptor
Amentoflavone (Standard) is the analytical standard of Amentoflavone. This product is intended for research and analytical applications. Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active GABA(A) negative modulator. Amentoflavone also shows anti-inflammatory, antioxidative, anti-viral, anti-tumor, anti-radiation, anti-fungal, antibacterial activity. Amentoflavone induces apoptosis and cell cycle arrest at sub-G1 phase ^[1] ^[3] .

Cat. No.	Product Name	Chemical Structure

HY-15306S

Eltrombopag-13C4

1 Publications Verification

Eltrombopag- ¹³C₄ (SB-497115- ¹³C₄) is ^{13 sup>C-labeled Z-Eltrombopag. Z-Eltrombopag is an orally active thrombopoietin-receptor non-peptide agonist with platelet-stimulating activity for the study of chronic immune thrombocytopenia. Eltrombopag also has strong inhibitory effects on multidrug-resistant Staphylococcus aureus (Staphylococcus aureus) and can induce apoptosis (apoptosis) in liver cancer cells ^[1] ^[3] .}

HY-N0898S

Catechin-13C3
Catechin- ¹³C₃ is the ¹³C-labeled Catechin. Catechin ((+)-Catechin) inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM.

HY-D0184S2

2'-Deoxycytidine-15N3
2'-Deoxycytidine- ¹⁵N₃ is the ¹⁵N labeled 2'-Deoxycytidine[1]. 2'-Deoxycytidine, a deoxyribonucleoside, could inhibit biological effects of Bromodeoxyuridine (Brdu)[2].

HY-D0184S3

2'-Deoxycytidine-13C9,15N3
2'-Deoxycytidine- ¹³C₉, ¹⁵N₃ (Deoxycytidine- ¹³C₉, ¹⁵N₃; Cytosine deoxyriboside- ¹³C₉, ¹⁵N₃; Deoxyribose cytidine- ¹³C₉, ¹⁵N₃) is ¹³C and ¹⁵N-labeled 2'-Deoxycytidine (HY-D0184). 2'-Deoxycytidine, a deoxyribonucleoside, could inhibit biological effects of Bromodeoxyuridine (Brdu).

HY-40354S

Tofacitinib-13C3
Tofacitinib- ¹³C₃ is the ¹³C-labeled Tofacitinib. Tofacitinib is an orally available JAK3/2/1 inhibitor with IC50s of 1, 20, and 112 nM, respectively.

HY-A0253S

Cefacetrile-13C3
Cefacetrile- ¹³C₃ is the ¹³C₃ labeled Cefacetrile.

HY-B0139AS

Flucytosine-15N3 hydrochloride
Flucytosine- ¹⁵N₃ hydrochloride is ¹⁵N labeled Flucytosine.

HY-B0234S

Estrone-13C3
Estrone- ¹³C₃ is the ¹³C-labeled Estrone. Estrone (E1) is a natural estrogenic hormone. Estrone is the main representative of the endogenous estrogens and is produced by several tissues, especially adipose tissue. Estrone is the result of the process of aromatization of androstenedione that occurs in fat cells[1][2].

HY-B1331S1

Cyromazine-13C3
Cyromazine- ¹³C₃ is the ¹³C₃ labeled Cyromazine. Cyromazine is a triazine insect growth regulator used as an insecticide and an acaricide. It is a cyclopropyl derivative of melamine. Cyromazine works by affecting the nervous system of the immature larval stages of certain insects.

HY-100196S1

Pyrroloquinoline quinone-13C3 sodium
Pyrroloquinoline quinone-13C3 (sodium) is an isotope of Pyrroloquinoline quinone. Pyrroloquinoline quinone (PQQ), a redox co-factor, is an anionic, redox-cycling orthoquinone. Pyrroloquinoline quinone is isolated from cultures of methylotropic bacteria and tissues of mammals. Pyrroloquinoline quinone is an essential nutrient for mammals and is important for immune function ^[1].

HY-B1804S

Tricaprilin-13C3
Tricaprilin-13C3 is a deuterated labeled Tricaprilin ^[1]. Tricaprilin (Trioctanoin) is used in study for patients with mild to moderate Alzheimer's disease and has a role as an anticonvulsant and a plant metabolite ^[3].

HY-W653853

Ritonavir-13C3
Ritonavir- ¹³C₃ is ¹³C labeled Ritonavir. Ritonavir (ABT 538) is an inhibitor of HIV protease used to treat HIV infection and AIDS. Ritonavir is also a SARS-CoV 3CL ^pro inhibitor with an IC₅₀ of 1.61 μM ^[1].

HY-B0389S18

D-Glucose-13C3-1
D-Glucose- ¹³C₃-1 is the ¹³C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].

HY-B0389S9

D-Glucose-13C3-2
D-Glucose- ¹³C₃-2 is the ¹³C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].

HY-W654126

Cytarabine-13C3
Cytarabine- ¹³C₃ (Cytosine β-D-arabinofuranoside- ¹³C₃) is ¹³C labeled Cytarabine ^[1].

HY-N0650S

L-Serine-13C3
L-Serine- ¹³C₃ is the ¹³C-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-B0495S4

Lamotrigine-13C3
Lamotrigine- ¹³C₃ is the ¹³C-labeled Lamotrigine. Lamotrigine (BW430C) is a potent and orally active anticonvulsant or antiepileptic agent. Lamotrigine selectively blocks voltage-gated Na+ channels, stabilizing presynaptic neuronal membranes and inhibiting glutamate release. Lamotrigine can be used for the research of epilepsy, focal seizure, et al[1][2].

HY-Y0219S

1,2,4-Triazole-13C2,15N3
NSC 83128- ¹³C₂, ¹⁵N₃ is the ¹³C and ¹⁵N labeled NSC 83128[1].

HY-N0680S3

Thiamine-13C3 hydrochloride
Thiamine- ¹³C₃ (hydrochloride) is the ¹³C-labeled Thiamine (hydrochloride). Thiamine hydrochloride (Thiamine chloride hydrochloride) is an essential micronutrient needed as a cofactor for many central metabolic enzymes.

HY-14605S

Rasagiline-13C3 mesylate
Rasagiline- ¹³C₃ ((R)-AGN1135- ¹³C₃; TVP1012- ¹³C₃) mesylateis the deuterium labeledRasagiline (mesylate)(HY-14605) ^[1]. Rasagiline (R-AGN1135) mesylate is a highly potent selective irreversible mitochondrial monoamine oxidase (MAO) inhibitor with IC₅₀s of 4.43?nM and 412?nM for rat brain MAO B and A activity, respectively .

HY-W700491

AalphaC-15N3

AalphaC- ¹⁵N₃ (2-Amino-α-carboline- ¹⁵N₃) is ¹⁵N labeled AalphaC. AalphaC (AαC) is a potential carcinogen with carcinogenic activity. AalphaC is an important biomarker in tobacco smoke and is associated with tobacco smoke exposure. Urinary concentrations of AalphaC are significantly higher in dedicated smokers than in non-smokers, indicating its importance in monitoring tobacco exposure. AalphaC levels increase significantly with increasing serum nicotine levels, indicating its close relationship with tobacco use. In addition, consuming high-temperature cooked beef significantly increases the amount of AalphaC in urine, while consuming vegetables is associated with a decrease in AalphaC concentrations. Smoking half a pack of cigarettes is associated with a significant increase in the amount of AalphaC, which further confirms the biological activity of AalphaC and its association with dietary habits ^[1] .

HY-Y0921S3

(±)-1,2-Propanediol-13C3
(±)-1,2-Propanediol- ¹³C₃ is ¹³C labeled (±)-1,2-Propanediol (HY-Y0921). (±)-1, 2-propanediol (1,2-(RS)-Propanediol) is an aliphatic alcohol that is often used as an excipient in many active molecular preparations to increase the solubility and stability of the active molecule. (±)-1, 2-propanediol can affect the neurobehavior of zebrafish ^[1] .

HY-B0150S1

Nicotinamide-15N,13C3
Nicotinamide- ¹⁵N, ¹³C₃ is the ¹³C-labeled and ¹⁵N-labeled Nicotinamide. Nicotinamide is a form of vitamin B3 that plays essential roles in cell physiology through facilitating NAD+ redox homeostasis and providing NAD+ as a substrate to a class of enzymes that catalyze non-redox reactions. Nicotinamide is an inhibitor of SIRT1.

HY-14605BS

Rasagiline-13C3 mesylate racemic

Rasagiline- ¹³C₃ (mesylate racemic) is a ¹³C-labeled Rasagiline mesylate racemic. Rasagiline mesylate racemic is a highly potent selective irreversible mitochondrial monoamine oxidase (MAO) inhibitor[1]. Rasagiline-13C3 (mesylate racemic) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-B0891S1

17α-Hydroxyprogesterone-13C3
17α-Hydroxyprogesterone- ¹³C₃ is the ¹³C-labeled 17α-Hydroxyprogesterone. 17α-Hydroxyprogesterone (17-Hydroxyprogesterone) is an endogenous progestogen as well as chemical intermediate in the biosynthesis of other steroid hormones, including the corticosteroids and the androgens and the estrogens.

HY-N0086S3

N6-Methyladenosine-13C3
N6-Methyladenosine- ¹³C₃ (6-Methyladenosine- ¹³C₃) is ¹³C-labeled N6-Methyladenosine (HY-N0086). N6-Methyladenosine is the most prevalent internal (non-cap) modification present in the messenger RNA (mRNA) of all higher eukaryotes. N6-Methyladenosine can modifies viral RNAs and has antiviral activities ^[1] ^[3].

HY-W777148

Anagrelide-13C3
Anagrelide- ¹³C₃ (BL 4162A- ¹³C₃) is ¹³C labeled Anagrelide ^[1].

HY-B0178AS

Guanidine-13C,15N3 hydrochloride
Guanidine- ¹³C, ¹⁵N₃ (hydrochloride)is the ¹³C-labeled and ¹⁵N-labeled Guanidine hydrochloride. Guanidine hydrochloride (Guanidinium chloride) a strong chaotrope, is also a strong denaturant of proteins[1][2].

HY-N0650S5

L-Serine-13C3,15N
L-Serine- ¹³C₃, ¹⁵N is the ¹³C- and ¹⁵N-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-113008AS

cis-Urocanic acid-13C3
cis-Urocanic acid- ¹³C₃ is the ¹³C-labeled cis-Urocanic acid. cis-Urocanic acid is a 5-HT2A receptor agonist. cis-Urocanic acid binds to 5-HT receptor with relatively high affinity (Kd=4.6 nM). cis-Urocanic acid is an immune modulator that induces immunosuppression by binding to the 5-HT2A receptor[1].

HY-B1342S3

Vitamin A-13C3
Vitamin A- ¹³C₃ (Vitamin A1- ¹³C₃; all-trans-Retinol- ¹³C₃) is a ¹³C-labeled Vitamin A/Vitamin A (HY-B1342). Vitamin A is an endogenous metabolite.

HY-B0158S5

Cytidine-13C9,15N3
Cytidine- ¹³C₉, ¹⁵N₃ is the ¹³C and ¹⁵N labeled Cytidine[1]. Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catecholamine synthesis, and mitochondrial function[2][3][4].

HY-W009162S5

Cytidine 5′-monophosphate-13C9,15N3 dilithium

Cytidine 5′-monophosphate- ¹³C₉, ¹⁵N₃ (5'-Cytidylic acid- ¹³C₉, ¹⁵N₃ dilithium; 5'-CMP- ¹³C₉, ¹⁵N₃) dilithium is ¹³C and ¹⁵N-labeled Cytidine 5'-monophosphate (HY-W009162). Cytidine 5'-monophosphate (5'-Cytidylic acid) is a nucleotide which is used as a monomer in RNA. Cytidine 5'-monophosphate consists of the nucleobase cytosine, the pentose sugar ribose, and the phosphate group.

HY-101400S2

Deoxycytidine triphosphate-13C9,15N3 dilithium

Deoxycytidine triphosphate- ¹³C₉, ¹⁵N₃ (dCTP- ¹³C₉, ¹⁵N₃ dilithium; 2′-Deoxycytidine-5′-triphosphate- ¹³C₉, ¹⁵N₃) dilithium is ¹³C and ¹⁵N-labeled Deoxycytidine triphosphate (HY-101400). Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.

HY-N0610AS2

Cinnamic acid-13C3
Cinnamic acid- ¹³C₃ (3-Phenylacrylic acid- ¹³C₃) is the ¹³C labeled Cinnamic acid (HY-N0610A). Cinnamic acid has potential use in cancer intervention, with IC₅₀s of 1-4.5 mM in glioblastoma, melanoma, prostate and lung carcinoma cells ^[1] .

HY-18569S4

3-Indoleacetic acid-13C6
3-Indoleacetic acid- ¹³C₆ is the ¹³C labeled 3-Indoleacetic acid[1]. 3-Indoleacetic acid (Indole-3-acetic acid) is the most common natural plant growth hormone of the auxin class. It can be added to cell culture medium to induce plant cell elongation and division ^[1].

HY-N0230S

β-Alanine-13C3,15N
β-Alanine- ¹³C₃, ¹⁵N is the ¹³C- and ¹⁵N-labeled β-Alanine. β-Alanine is a non-essential amino acid that is shown to be metabolized into carnosine, which functions as an intracellular buffer.

HY-125818S6

Cytidine-5'-triphosphate-15N3 dilithium

Cytidine-5'-triphosphate- ¹⁵N₃ (Cytidine triphosphate- ¹⁵N₃ dilithium; 5'-CTP- ¹⁵N₃) dilithium is ¹⁵N labeled Cytidine-5'-triphosphate (HY-125818). Cytidine 5′-triphosphate (Cytidine triphosphate; 5'-CTP) is a nucleoside triphosphate and serves as a building block for nucleotides and nucleic acids, lipid biosynthesis. Cytidine triphosphate synthase can catalyze the formation of cytidine 5′-triphosphate from uridine 5′-triphosphate (UTP). Cytidine 5′-triphosphate is an essential biomolecule?in the de novo?pyrimidine biosynthetic pathway in?T. gondii.

HY-101400S3

Deoxycytidine triphosphate-15N3 dilithium
Deoxycytidine triphosphate- ¹⁵N₃ (dCTP- ¹⁵N₃ dilithium; 2′-Deoxycytidine-5′-triphosphate- ¹⁵N₃) dilithium is ¹⁵N labeled Deoxycytidine triphosphate (HY-101400). Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.

HY-B1204S2

Histamine-13C5, 15N3
Histamine- ¹³C₅, ¹⁵N₃ (Ergamine- ¹³C₅, ¹⁵N₃) is the ¹³C and ¹⁵N labeled isotope of Histamine (HY-B1204). Histamine is an organic nitrogen compound that participates in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter ^[1].

HY-15129S

O-Phospho-L-serine-13C3,15N
O-Phospho-L-serine- ¹³C₃, ¹⁵N is the ¹³C- and ¹⁵N-labeled O-Phospho-L-serine. O-Phospho-L-serine is the immediate precursor to L-serine in the serine synthesis pathway, and an agonist at the group III mGluR receptors (mGluR4, mGluR6, mGluR7, and mGluR8); O-Phospho-L-serine also acts as a weak antagonist for mGluR1 and a potent antagonist for mGluR2[1].

HY-B0412S3

Estriol-13C3
Estriol- ¹³C₃ is the ¹³C-labeled Estriol. Estriol is an antagonist of the G-protein coupled estrogen receptor in estrogen receptor-negative breast cancer cells.

HY-B1659S5

Glycerol-13C3
Glycerol- ¹³C₃ is the ¹³C labeled Glycerol[1]. Glycerol is used in sample preparation and gel formation for polyacrylamide gel electrophoresis[2][3][4].

HY-N0136S1

(±)-Taxifolin-13C3

(±)-Taxifolin-13C3 ((±)-Dihydroquercetin-13C3) is a derivative of (±)-Taxifolin, labeled with 13C3. (±)-Taxifolin is the racemate of Taxifolin. Taxifolin exhibits important anti-tyrosinase activity. Taxifolin exhibits significant inhibitory activity against collagenase with an IC₅₀ value of 193.3 μM ^[1]. Taxifolin is an important natural compound with antifibrotic activity. Taxifolin is a free radical scavenger with antioxidant capacity .

HY-B0111RS

Drospirenone-13C3
Drospirenone- ¹³C₃ is ¹³C labeled Drospirenone. Drospirenone (Dihydrospirorenone) is a synthetic progesterone that is an analog of Spironolactone ^[1].

HY-B0158S6

Cytidine-15N3
Cytidine- ¹⁵N₃ is the ¹⁵N labeled Cytidine[1]. Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catecholamine synthesis, and mitochondrial function[2][3][4].

HY-W009162S4

Cytidine 5′-monophosphate-15N3 dilithium
Cytidine 5′-monophosphate- ¹⁵N₃ (5'-Cytidylic acid- ¹⁵N₃ dilithium; 5'-CMP- ¹⁵N₃) dilithium is ¹⁵N labeled Cytidine 5'-monophosphate (HY-W009162). Cytidine 5'-monophosphate (5'-Cytidylic acid) is a nucleotide which is used as a monomer in RNA. Cytidine 5'-monophosphate consists of the nucleobase cytosine, the pentose sugar ribose, and the phosphate group.

HY-N0304S1

L-DOPA-13C6
L-DOPA- ¹³C₆ is the ¹³C-labled L-DOPA ^[1]. L-DOPA (Levodopa) is an orally active metabolic precursor of neurotransmitters dopamine. L-DOPA can cross the blood-brain barrier and is converted into dopamine in the brain. L-DOPA has anti-allodynic effects and the potential for Parkinson's disease ^[3] .

HY-Y0721S

3-Bromofluorobenzene-13C6
3-Bromofluorobenzene- ¹³C₆ is the ¹³C labeled 3-Bromofluorobenzene[1].

HY-110382S

13C20,15N10-Cyclic di-GMP sodium

¹³C20, ¹⁵N10-Cyclic di-GMP ( ¹³C20, ¹⁵N10-c-di-GMP) is ¹³C and ¹⁵N labeled Cyclic-di-GMP (disodium). Cyclic-di-GMP disodium is a STING agonist and a bacterial second messenger that coordinates different aspects of bacterial growth and behavior, including motility, virulence, biofilm formation, and cell cycle progression. Cyclic-di-GMP disodium has anti-cancer cell proliferation activity and also induces elevated CD4 receptor expression and cell cycle arrest. Cyclic-di-GMP disodium can be used in cancer research ^[1] ^[3] .

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Species:	Human (27) Mouse (5) Rat (1) Bovine (2) Cynomolgus (3) Canine (3)
Tag:	GFP (3) His (29) Tag Free (5) Strep (5) Avi (4) GST (2) Trx (1) Fc (4) Flag (7)
Source:	HEK293 (26) E. coli Cell-free (1) CHO (1) Sf9 insect cells (2) E. coli (11)


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