Search Result

Results for "

15:0 Cholesteryl ester-d<sub>7</sub>

" in MedChemExpress (MCE) Product Catalog:

By Targets:	CETP (8) P-glycoprotein (11) 11β-HSD (3) 17β-HSD (1) 5 alpha Reductase (4) 5-HT Receptor (70) Acetolactate Synthase (ALS) (1) Acyltransferase (4) ADC Cytotoxin (12) Adenosine Receptor (8) Adrenergic Receptor (75) AIM2 (1) Akt (4) Aldehyde Dehydrogenase (ALDH) (1) Aldose Reductase (2) Amino Acid Derivatives (2) Aminopeptidase (2) AMPK (7) Amyloid-β (8) Anaplastic lymphoma kinase (ALK) (8) Androgen Receptor (18) Angiotensin Receptor (22) Angiotensin-converting Enzyme (ACE) (14) Antibiotic (156) Antifolate (6) Apical Sodium-Dependent Bile Acid Transporter (2) Apoptosis (235) Aryl Hydrocarbon Receptor (5) ATM/ATR (2) ATP Citrate Lyase (2) ATP Synthase (1) ATTECs (1) Aurora Kinase (1) Autophagy (272) Bacterial (238) Bcl-2 Family (3) Bcr-Abl (11) BCRP (2) Beta-lactamase (2) Beta-secretase (1) Biochemical Assay Reagents (37) BRK (1) Btk (4) c-Fms (3) c-Kit (15) c-Met/HGFR (5) c-Myc (1) Calcineurin (2) Calcium Channel (58) Cannabinoid Receptor (10) Carbonic Anhydrase (7) Casein Kinase (2) Caspase (4) CaSR (2) Cathepsin (1) CD73 (1) CDK (14) CFTR (5) CGRP Receptor (2) Checkpoint Kinase (Chk) (1) Chloride Channel (2) Cholinesterase (ChE) (17) Complement System (5) COMT (5) COX (62) CRFR (1) CRISPR/Cas9 (3) Cuproptosis (1) CXCR (1) Cyclic GMP-AMP Synthase (1) Cyclophilin (2) Cytochrome P450 (28) Dengue virus (2) Deubiquitinase (1) Dihydroorotate Dehydrogenase (1) Dipeptidyl Peptidase (14) Discoidin Domain Receptor (1) Disulfidptosis (4) DNA Alkylator/Crosslinker (9) DNA Methyltransferase (3) DNA-PK (2) DNA/RNA Synthesis (73) Dopamine Receptor (45) Drug Metabolite (57) Drug-Linker Conjugates for ADC (6) DYRK (2) E1/E2/E3 Enzyme (4) EBI2/GPR183 (1) EGFR (20) Elastase (1) Endogenous Metabolite (780) Endothelin Receptor (4) Enterovirus (5) Epigenetic Reader Domain (6) ERK (7) Estrogen Receptor/ERR (39) Factor Xa (6) FAK (2) Fatty Acid Synthase (FASN) (3) Ferroptosis (43) FGFR (11) FKBP (3) Flavivirus (4) FLT3 (7) Fluorescent Dye (4) Fungal (59) FXR (5) G protein-coupled Bile Acid Receptor 1 (2) GABA Receptor (26) Gap Junction Protein (2) Glucocorticoid Receptor (26) Glucosidase (1) Glucosylceramide Synthase (GCS) (2) Glutathione Reductase (1) Glutathione S-transferase (1) GlyT (2) GnRH Receptor (3) GPR35 (1) GPR55 (2) GSK-3 (4) HBV (8) HCV (19) HCV Protease (3) HDAC (23) Hedgehog (3) Hexokinase (1) HIF/HIF Prolyl-Hydroxylase (2) Histamine Receptor (32) Histone Acetyltransferase (7) Histone Demethylase (6) Histone Methyltransferase (5) HIV (56) HIV Integrase (11) HIV Protease (12) HMG-CoA Reductase (HMGCR) (16) HSP (5) HSV (12) IGF-1R (3) iGluR (19) IKK (2) Imidazoline Receptor (3) Indoleamine 2,3-Dioxygenase (IDO) (1) Influenza Virus (31) Insulin Receptor (1) Integrin (1) Interleukin Related (5) IRE1 (1) Isotope-Labeled Compounds (2076) JAK (8) JNK (4) Keap1-Nrf2 (10) Ketohexokinase (2) Kinesin (1) Leukotriene Receptor (9) Ligands for E3 Ligase (7) Ligands for Target Protein for PROTAC (2) Liposome (5) Lipoxygenase (5) LPL Receptor (6) mAChR (35) MARCKS (1) MDM-2/p53 (8) MEK (3) Melanocortin Receptor (1) Melatonin Receptor (8) mGluR (8) MicroRNA (17) Microtubule/Tubulin (19) Mineralocorticoid Receptor (10) Mitochondrial Metabolism (7) Mitophagy (35) MMP (6) Molecular Glues (11) Monoamine Oxidase (8) Monoamine Transporter (2) mTOR (4) Myosin (4) Na+/H+ Exchanger (NHE) (2) Na+/K+ ATPase (5) nAChR (13) NADPH Oxidase (2) Necroptosis (2) Neprilysin (7) Neurokinin Receptor (3) Neurotensin Receptor (1) NF-κB (34) NO Synthase (19) NOD-like Receptor (NLR) (3) Notch (6) Nuclear Hormone Receptor 4A/NR4A (2) Nucleoside Antimetabolite/Analog (57) Opioid Receptor (4) Orexin Receptor (OX Receptor) (1) Organoid (1) Orthopoxvirus (10) Oxidative Phosphorylation (1) Oxytocin Receptor (1) P2X Receptor (2) P2Y Receptor (7) p38 MAPK (7) PAK (7) Parasite (68) PARP (4) PDGFR (19) PGC-1α (1) PGE synthase (1) Phosphatase (9) Phosphodiesterase (PDE) (23) Phospholipase (5) PI3K (8) PI5P4K (1) Pim (1) PIN1 (1) PKA (4) PKC (8) Polo-like Kinase (PLK) (1) Potassium Channel (25) PPAR (22) Progesterone Receptor (24) Prostaglandin Receptor (21) PROTAC Linkers (2) PROTACs (4) Protease Activated Receptor (PAR) (1) Proteasome (3) Protein Arginine Deiminase (1) Proton Pump (22) Protoporphyrinogen IX oxidase (1) Raf (7) RAR/RXR (6) Ras (2) Reactive Oxygen Species (40) Renin (2) RET (6) Reverse Transcriptase (8) ROCK (2) ROS Kinase (5) RSV (8) SARS-CoV (37) Ser/Thr Protease (3) Serotonin Transporter (24) SGLT (6) Sigma Receptor (1) Sirtuin (7) Small Interfering RNA (siRNA) (4) Sodium Channel (27) Src (6) STAT (6) STING (2) Syk (1) TAM Receptor (3) Tau Protein (1) TGF-beta/Smad (4) Thrombin (9) Thrombopoietin Receptor (3) Thymidylate Synthase (5) Thyroid Hormone Receptor (6) Tie (1) TNF Receptor (5) Toll-like Receptor (TLR) (5) TOPK (1) Topoisomerase (24) Trk Receptor (3) TRP Channel (14) Tyrosinase (6) Vasopressin Receptor (2) VD/VDR (13) VEGFR (26) Virus Protease (14) Wee1 (1) Xanthine Oxidase (5) β-catenin (4) γ-secretase (1)
By Research Areas:	Cancer (810) Cardiovascular Disease (244) Endocrinology (189) Infection (402) Inflammation/Immunology (389) Metabolic Disease (401) Neurological Disease (402)
Click Chemistry:	Azide (3) Alkynes (14)
Oligonucleotides:	miRNA mimics (4) miRNA agomirs (4) miRNA antagomirs (4) Nucleosides and their Analogs (1) Nucleoside Phosphoramidites (1) MicroRNAs (16) Pre-designed siRNA Sets (4) Cationic Lipids (2) miRNA inhibitors (4) Cholesterol (4) siRNAs (4) Sweetening Agents (1)

3252

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

2933

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Oligonucleotides

Targets Recommended: CETP P-glycoprotein

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-146796S

15:0 Cholesteryl ester-d7	Isotope-Labeled Compounds	Others
15:0 Cholesteryl ester-d₇ is deuterium labeled 15:0 Cholesteryl ester.

HY-W329357

15:0 Lyso PC	Biochemical Assay Reagents
15:0 Lyso PC is a kind of biochemical reagent.

HY-146842S

15:0 Lyso PE-d5	Isotope-Labeled Compounds	Others
15:0 Lyso PE-d₅ is deuterium labeled 15:0 Lyso PE.

HY-146854S

15:0 Lyso PG-d5	Isotope-Labeled Compounds	Others
15:0 Lyso PG-d₅ is deuterium labeled 15:0 Lyso PG.

HY-146925S

15:0 Lyso PC-d5	Isotope-Labeled Compounds	Others
15:0 Lyso PC-d₅ is deuterium labeled 15:0 Lyso PC.

HY-146901S

15:0 SM (d18:1/15:0)-d9	Isotope-Labeled Compounds	Others
15:0 SM (d18:1/15:0)-d₉ is deuterium labeled 15:0 SM (d18:1/15:0).

HY-146774S

*14:1 cholesteryl* ester-d7**	Isotope-Labeled Compounds	Others
14:1 cholesteryl ester-d₇ is deuterium labeled 14:1 cholesteryl ester.

HY-146779S

*16:1 Cholesteryl* ester-d7**	Isotope-Labeled Compounds	Others
16:1 Cholesteryl ester-d₇ is deuterium labeled 16:1 Cholesteryl ester.

HY-146781S

*20:3 Cholesteryl* ester-d7**	Isotope-Labeled Compounds	Others
20:3 Cholesteryl ester-d₇ is deuterium labeled 20:3 Cholesteryl ester.

HY-RS13999

SUB1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SUB1 Human Pre-designed siRNA Set A contains three designed siRNAs for SUB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SUB1 Human Pre-designed siRNA Set A SUB1 Human Pre-designed siRNA Set A

HY-146227

DNA topoisomerase II inhibitor 1	Topoisomerase Apoptosis	Cancer
DNA topoisomerase II inhibitor 1 (compound 8ed) is a potent DNA topoisomerase II inhibitor. DNA topoisomerase II inhibitor 1 shows anti-proliferative activity. DNA topoisomerase II inhibitor 1 induces apoptosis and cell cycle arrest at sub G1 phase .

HY-Y0054S

Isocyanic acid, p-tolyl ester-d7 1-Isocyanato-4-methylbenzene-d<sub>7sub>; 4-Isocyanatotoluene-d<sub>7sub>	Isotope-Labeled Compounds	Others
Isocyanic acid, p-tolyl ester-d₇ is the deuterium labeled Isocyanic acid, p-tolyl ester[1].

HY-146799S

15:0-18:1-15:0 TG-d7	Isotope-Labeled Compounds	Others
15:0-18:1-15:0 TG-d₇ is deuterium labeled 15:0-18:1-15:0 TG.

HY-146913S

15:0-18:1-15:0 TG-d5	Isotope-Labeled Compounds	Others
15:0-18:1-15:0 TG-d₅ is deuterium labeled 15:0-18:1-15:0 TG.

HY-W674124

Tripentadecanoin TG(15:0/15:0/15:0); 1,2,3-Tripentadecanoyl glycerol	Others	Others
Tripentadecanoin (TG(15:0/15:0/15:0)) is a triacylglycerol that contains pentadecanoic acid (HY-W004283) at the sn-1, sn-2, and sn-3 positions. It has been found in various grapes. 1,2,3-Tripentadecanoyl glycerol has been used as a standard for the detection of triacylglycerols in human plasma by LC-MS.

HY-10844S1

Pretomanid-d5 PA-824-d<sub>5sub>; (S)-PA 824-d<sub>5sub>	Antibiotic Bacterial Isotope-Labeled Compounds	Infection Cancer
Pretomanid-d₅ is deuterated labeled Pretomanid (HY-10844). Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 μg/mL.

HY-165869

Cholesteryl 11(E)-vaccenate Vaccenic acid Cholesteryl ester	Others	Metabolic Disease
Cholesteryl 11(E)-vaccenate (Vaccenic acid cholesteryl ester) is an ester product.

HY-166276

Cholesteryl petroselinate Cholesteryl cis-6-octadecenoate	Others	Metabolic Disease
Cholesteryl petroselinate (Cholesteryl cis-6-octadecenoate) is an ester product.

HY-131389

Cholesteryl heptadecanoate	Others	Others
Cholesteryl heptadecanoate is a cholesteryl ester internal standard that accurately determines the concentration of free cholesterol in cells without hydrolyzing triglycerides. Cholesteryl heptadecanoate can be used for the quantitative determination of cholesteryl esters by GC or LC mass spectrometry .

HY-W010697

Cholesteryl linoleate	Endogenous Metabolite	Metabolic Disease
Cholesteryl linoleate is shown to be the major cholesteryl ester contained in LDL and atherosclerotic lesions.

HY-112624M

*Dextran T150 (MW 150,000)* Dextran 150; Dextran D150; Dextran T150(MW 130000-170000)	Biochemical Assay Reagents	Others
Dextran T150 MW 150,000 (Dextran D150; Dextran T150 MW 130000-170000) is a polymer of anhydroglucose with the average molecular weight of 150000. Dextran T150 MW 150,000 exhibits good biodegradability and good biocompatibility, that is utilized in food, pharmaceutics, cosmetics, and research area .

HY-166974

Polysarcosine 150 pSar 150	Biochemical Assay Reagents	Others
Polysarcosine 150 (pSar 150) is a hydrophilic alternative to PEG that has good targeted drug delivery properties and can remain in the bloodstream longer. Polysarcosine 150 can be used in drug delivery research .

HY-167068

Azide-pSar150 Azide-Polysarcosine150	Biochemical Assay Reagents	Others
Azide-pSar150 (Azide-Polysarcosine150) is a pSar-lipid derivative. Azide-pSar150 is a hydrophilic alternative to PEG and can be used in drug delivery research .

HY-167066

DSPE-pSar150 DSPE-Polysarcosine150	Biochemical Assay Reagents	Others
DSPE-pSar150 (DSPE-Polysarcosine150) is a pSar-lipid derivative. DSPE-pSar150 is a hydrophilic alternative to PEG and can be used in drug delivery research .

HY-W013122

Cholesteryl n-butyrate Cholesteryl butyrate	Biochemical Assay Reagents	Cancer
Cholesteryl n-butyrate is a cholesterol ester composed of cholesterol and butyrate, two naturally occurring substances. Cholesteryl n-butyrate can be used to synthesize solid lipid nanoparticles (SLNs) with inhibitory activity on the adhesion and migration of colon cancer cells, providing a delivery system for the anticancer drug butyrate .

HY-W010800

Cholesteryl hemisuccinate	Topoisomerase DNA/RNA Synthesis Apoptosis Necroptosis	Cancer
Cholesteryl hemisuccinate is a with hepatoprotective an anticancer activity. Cholesteryl hemisuccinate inhibits Acetaminophen (AAP, HY-66005) hepatotoxicity, and prevents AAP-induced hepatic apoptosis and necrosis. Cholesteryl hemisuccinate inhibits DNA polymerase and DNA topoisomerase to inhibit DNA replication and repair and cell division. Thus, Cholesteryl hemisuccinate inhibits tumor growth .

HY-133962

Cholesteryl erucate	Biochemical Assay Reagents	Others
Cholesteryl erucate is a cholesterol ester. It has been used as a standard for the quantification of cholesteryl esters in human meibomian gland secretions.

HY-W010708R

Cholesteryl palmitate (Standard)	Endogenous Metabolite	Inflammation/Immunology
Cholesteryl palmitate (Standard) is the analytical standard of Cholesteryl palmitate. This product is intended for research and analytical applications. Cholesteryl palmitate is a useful prognostic biomarker for chronic interstitial pneumonia (CIP).

HY-W010708S

Cholesteryl palmitate-d9	Endogenous Metabolite	Inflammation/Immunology
Cholesteryl palmitate-d₉ is the deuterium labeled Cholesteryl palmitate. Cholesteryl palmitate is a useful prognostic biomarker for chronic interstitial pneumonia (CIP).

HY-107327S

Carazolol-d7 (±)-Carazolol-d<sub>7sub>; DL-Carazolol-d<sub>7sub>; Suacron-d<sub>7sub>	Adrenergic Receptor	Others
Carazolol-d₇ is the deuterium labeled Carazolol[1].

HY-N0006S

Demethoxycurcumin-d7 Curcumin II-d<sub>7sub>; Desmethoxycurcumin-d<sub>7sub>; Monodemethoxycurcumin-d<sub>7sub>	Isotope-Labeled Compounds Apoptosis Autophagy Bacterial	Inflammation/Immunology Cancer
Demethoxycurcumin-d₇ is the deuterium labeled Demethoxycurcumin. Demethoxycurcumin(Curcumin II), a major active curcuminoid, possess anti-inflammatory properties; also exert cytotoxic effects in human cancer cells via induction of apoptosis.

HY-113217S

Cholesteryl oleate-d7	Endogenous Metabolite	Others
Cholesteryl oleate-d₇ is deuterium labeled Cholesteryl oleate. Cholesteryl oleate is an esterified form of Cholesterol. Cholesteryl oleate can be used in the generation of solid lipid nanoparticle (SLN, a nanoparticle-based method for gene therapy)[1

HY-166285

Cholesteryl petroselaidate	Others	Metabolic Disease
Cholesteryl petroselaidate is an ester product.

HY-166286

Cholesteryl pentadecanoate	Others	Metabolic Disease
Cholesteryl pentadecanoate is an ester product.

HY-166302

Cholesteryl docosapentaenoate	Others	Metabolic Disease
Cholesteryl docosapentaenoate is an ester product.

HY-166268

Cholesteryl undecanoate	Others	Metabolic Disease
Cholesteryl undecanoate is an ester product.

HY-166271

Cholesteryl tridecanoate	Others	Metabolic Disease
Cholesteryl tridecanoate is an ester product.

HY-166274

Cholesteryl tricosanoate	Others	Metabolic Disease
Cholesteryl tricosanoate is an ester product.

HY-166289

Cholesteryl myristoleate	Others	Metabolic Disease
Cholesteryl myristoleate is an ester product.

HY-166291

Cholesteryl myristelaidate	Others	Metabolic Disease
Cholesteryl myristelaidate is an ester product.

HY-166294

Cholesteryl isovalerate	Others	Metabolic Disease
Cholesteryl isovalerate is an ester product.

HY-166296

Cholesteryl heneicosanoate	Others	Metabolic Disease
Cholesteryl heneicosanoate is an ester product.

HY-W010708S1

Cholesteryl palmitate-d7	Isotope-Labeled Compounds Endogenous Metabolite	Inflammation/Immunology
Cholesteryl palmitate-d₇ is deuterium labeled Cholesteryl palmitate. Cholesteryl palmitate is a useful prognostic biomarker for chronic interstitial pneumonia (CIP)[1].

HY-113217

Cholesteryl oleate	Liposome Endogenous Metabolite	Others
Cholesteryl oleate is an esterified form of Cholesterol. Cholesteryl oleate can be used in the generation of solid lipid nanoparticle (SLN, a nanoparticle-based method for gene therapy) .

HY-125910

Cholesteryl Linolenate	Endogenous Metabolite	Metabolic Disease
Cholesteryl Linolenate is an endogenous metabolite.

HY-113369

Cholesteryl arachidonate	Endogenous Metabolite	Metabolic Disease
Cholesteryl arachidonate is an endogenous metabolite.

HY-147740

WEHI-150	DNA Alkylator/Crosslinker	Cancer
WEHI-150 is a replica of mitoxantrone, is a portent DNA interstrand crosslinkWEHI-150 forms covalent adducts at CpG sequences and exhibits a preference for methylated CpG sites. Formaldehyde-activated WEHI-150 induces DNA interstrand crosslinks. Formaldehyde-activated WEHI-150 shows Concentration-dependent transcription blockages. WEHI-150 can mediate covalent adducts that are independent of interactions with the N-2 of guanine and is capable of adduct formation at novel DNA sequences .

HY-66005S2

Acetaminophen-d7 Paracetamol-d<sub>7sub>; 4-Acetamidophenol-d<sub>7sub>; 4'-Hydroxyacetanilide-d<sub>7sub>	COX Endogenous Metabolite Histone Acetyltransferase	Inflammation/Immunology
Acetaminophen-d₇ is the deuterium labeled Acetaminophen. Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM; is a widely used antipyretic and analgesic agent. Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor.

HY-B0389S6

D-Glucose-d7 Glucose-d<sub>7sub>; D-(+)-Glucose-d<sub>7sub>; Dextrose-d<sub>7sub>	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
D-Glucose-d₇7 is the deuterium labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].

HY-107352S

Fosfenopril-d7 Fosinoprilat-d<sub>7sub>; Fosinoprilic acid-d<sub>7sub>; SQ 27519-d<sub>7sub>	Angiotensin-converting Enzyme (ACE) Interleukin Related NF-κB TNF Receptor Toll-like Receptor (TLR) Isotope-Labeled Compounds	Others
Fosfenopril-d₇ is deuterium labeled Fosfenopril.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W010697

Cholesteryl linoleate	Structural Classification Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite
Cholesteryl linoleate is shown to be the major cholesteryl ester contained in LDL and atherosclerotic lesions.

HY-113217

Cholesteryl oleate	Structural Classification Microorganisms Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields Steroids	Liposome Endogenous Metabolite
Cholesteryl oleate is an esterified form of Cholesterol. Cholesteryl oleate can be used in the generation of solid lipid nanoparticle (SLN, a nanoparticle-based method for gene therapy) .

HY-125910

Cholesteryl Linolenate	Structural Classification Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite
Cholesteryl Linolenate is an endogenous metabolite.

HY-113369

Cholesteryl arachidonate	Structural Classification Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite
Cholesteryl arachidonate is an endogenous metabolite.

HY-W010708

Cholesteryl palmitate	Structural Classification Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields Steroids	Endogenous Metabolite
Cholesteryl palmitate is a useful prognostic biomarker for chronic interstitial pneumonia (CIP).

HY-N2339

Cholesteryl behenate 1 Publications Verification Cholesteryl docosanoate; Cholesterol behenate	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Cholesteryl behenate is a cholesterol ester associated with the neutral core of low density lipoprotein Receptor-LDL complexes are taken up by lysosomes and hydrolyzed to release cholesterol from the esters.

HY-125833

Alpha-Naphthoflavone 5+ Cited Publications	Flavonoids Flavones Source classification Indigofera heterantha Wall. ex Brand. Plants Compositae Disease Research Fields Cancer	Cytochrome P450 Aryl Hydrocarbon Receptor Apoptosis
Alpha-Naphthoflavone is an orally active flavonoid that is a potent, competitive inhibitor of aromatase< b>aromatase. < b > IC < sub > 50 < / sub > < / b > and < b > K < sub > I < / sub > < / b > value were 0.5 and 0.2 microns. Alpha-Naphthoflavone can inhibit cell proliferation and induce apoptosis .

HY-111355B

Cholesteryl sulfate sodium	Structural Classification Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite
Cholesteryl sulfate sodium is an important regulatory molecule. Cholesterol sulfate sodium is a component of cell membranes where it has a stabilizing role and protects erythrocytes from osmotic lysis and regulating sperm capacitation .

HY-107823

Cholesteryl acetate Cholesterol 3-acetate; Cholesterin acetate; Cholesterol 3β-acetate	Structural Classification Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite
Cholesteryl acetate (Cholesterol 3-acetate) is a cholesterol ester .

HY-W010708R

Cholesteryl palmitate (Standard)	Structural Classification Source classification Endogenous metabolite Steroids	Endogenous Metabolite
Cholesteryl palmitate (Standard) is the analytical standard of Cholesteryl palmitate. This product is intended for research and analytical applications. Cholesteryl palmitate is a useful prognostic biomarker for chronic interstitial pneumonia (CIP).

HY-N11799

Neochilenin 3-O-Methylquercetin 4′-O-glucoside	Structural Classification Flavonoids Source classification Plants Compositae Other Flavonoids	Others
Neochilenin (3-O-Methylquercetin 4 '-O-glucoside) is a glycoside of 3-O-methylquercetin, which can be isolated from the sub-family Cereoideae (Cactaceae). .

HY-W011474

Geranylgeraniol	Structural Classification Natural Products Microorganisms	NF-κB
Geranylgeraniol is an orally acitve vitamin K₂ sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model .

HY-P2274

Argifin	Infection Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields	Parasite
Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms, with IC₅₀s of 0.025 μM, 6.4 μM , 1.1 μM and 4.5 μM for SmChiA (Serratia marcescens chitinaese A), SmChiB, Aspergillus fumigatus chitinase B1 and human chitotriosidase, respectively .

HY-N10192

Aculene D	Infection Microorganisms Classification of Application Fields Terpenoids Sesquiterpenes Source classification Disease Research Fields	Endogenous Metabolite Bacterial
Aculene D, a fungal metabolite, shows quorum sensing (QS) inhibitory activity against Chromobacterium violaceum CV026, and could significantly reduce violacein production in N-hexanoyl-l-homoserine lactone (C6-HSL) induced C. violaceum CV026 cultures at sub-inhibitory concentrations .

HY-W011474R

Geranylgeraniol (Standard)	Structural Classification Natural Products Microorganisms	NF-κB
Geranylgeraniol (Standard) is the analytical standard of Geranylgeraniol. This product is intended for research and analytical applications. Geranylgeraniol is an orally acitve vitamin K2 sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model [4].

HY-N0662

Amentoflavone 5+ Cited Publications Didemethyl-ginkgetin	Structural Classification Flavonoids Classification of Application Fields Source classification Phenols Polyphenols Selaginellaceae Plants Biflavones Selaginella tamariscina (P. Beauv.) Spring Disease Research Fields Cancer	Reactive Oxygen Species Apoptosis Bacterial Fungal RSV GABA Receptor
Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active GABA(A) negative modulator. Amentoflavone also shows anti-inflammatory, antioxidative, anti-viral, anti-tumor, anti-radiation, anti-fungal, antibacterial activity. Amentoflavone induces apoptosis and cell cycle arrest at sub-G1 phase .

HY-N0662R

Amentoflavone (Standard)	Structural Classification Flavonoids Source classification Phenols Polyphenols Selaginellaceae Plants Biflavones Selaginella tamariscina (P. Beauv.) Spring	Reactive Oxygen Species Apoptosis Bacterial Fungal RSV GABA Receptor
Amentoflavone (Standard) is the analytical standard of Amentoflavone. This product is intended for research and analytical applications. Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active GABA(A) negative modulator. Amentoflavone also shows anti-inflammatory, antioxidative, anti-viral, anti-tumor, anti-radiation, anti-fungal, antibacterial activity. Amentoflavone induces apoptosis and cell cycle arrest at sub-G1 phase .

HY-N2020

Anacardic Acid 5+ Cited Publications Hydroginkgolic acid; Ginkgolic Acid C15:0	Structural Classification Ginkgoaceae Classification of Application Fields Source classification Plants Ginkgo biloba Monophenols Ketones, Aldehydes, Acids Phenols Anacardium occidentaleL. Disease Research Fields Anacardiaceae Cancer	Histone Acetyltransferase Epigenetic Reader Domain Bacterial
Anacardic Acid, extracted from cashew nut shell liquid, is a histone acetyltransferase inhibitor, inhibits HAT activity of p300 and PCAF, with IC₅₀s of ∼8.5 μM and ∼5 μM, respectively.

HY-N2338

Cholesterol myristate Cholesteryl myristate; Cholesteryl tetradecanoate	Structural Classification Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Steroids Cancer	nAChR GABA Receptor Potassium Channel Endogenous Metabolite
Cholesterol myristate is a natural steroid present in traditional Chinese medicine. Cholesterol myristate binds to several ion channels such as the nicotinic acetylcholine receptor, GABAA receptor, and the inward-rectifier potassium ion channel.

HY-B0504S

Creatinine-d3 3 Publications Verification NSC13123-d<sub>3sub>	Classification of Application Fields Metabolic Disease Disease Research Fields	Endogenous Metabolite
Creatinine-d₃ is a deuterium labeled Creatinine. Creatinine is a break-down product of creatine phosphate in muscle[1].

HY-N8353

Stachybotramide	Structural Classification Natural Products Microorganisms Source classification	Others
Stachybotramide is a natural fungal metabolite with the property of modulating the activity of cholesteryl ester transfer protein (CETP). Stachybotramide stimulates the transfer of cholesteryl esters (CE) from high-density lipoprotein (HDL) to very-low-density lipoprotein (VLDL) and low-density lipoprotein (LDL), increasing the transfer efficiency by 1.3- to 1.5-fold. Stachybotramide slightly reduced the transfer of cholesteryl esters from LDL and VLDL to HDL at 0.5 mM. The effect of Stachybotramide on the transfer of triglycerides (TG) from HDL was not significant. By these results, Stachybotramide was shown to preferentially stimulate the CETP-mediated transfer of cholesteryl esters from HDL to VLDL and LDL .

HY-N9524

Ilexoside XLVIII	Aquifoliaceae Triterpenes Structural Classification Ilex latifolia Thunb. Classification of Application Fields Terpenoids Source classification Metabolic Disease Plants Disease Research Fields	Acyltransferase
Ilexoside XLVIII is an acyl CoA cholesteryl acyl transferase (ACAT) inhibitor. Ilexoside XLVIII is a triterpene saponin isolated from an aqueous extract of the leaves of Ilex kudincha .

HY-N7962

Cornoside	Phyla nodiflora (L.) E. L. Greene Quinones Classification of Application Fields Verbenaceae Source classification Benzene Quinones Plants Disease Research Fields Inflammation/Immunology	Aldose Reductase
Cornoside is a phenolic glycoside and has inhibitory effect on rat lens aldose reductase (AR) with an IC₅₀ of 150 μM .

HY-N6808

Rebaudioside B	Structural Classification Trifolium hybridum L. other families Classification of Application Fields Terpenoids Source classification Other Diseases Diterpenoids Plants Compositae Disease Research Fields	Others
Rebaudioside B is the minor constituent isolated from the leaves of Stevia rebaudiana Bertoni. Rebaudioside B tastes about 150 times sweeter than sucrose .

HY-134914

Fosmidomycin	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Antibiotic Parasite
Fosmidomycin is an orally active antibiotic, which exhibits antimalarial activity through inhibition of 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DOXP reductoisomerase). Fosmidomycin inhibits P. falciparum strains 3D7, HB3, Dd2 and A2, with IC₅₀s of 150, 71, 170 and 150 ng/mL, respectively. Fosmidomycin exhibits synergistic effect with Clindamycin (HY-B1455), and ameliorates malaria in mouse model .

HY-N1116

Tsugafolin	Structural Classification Flavonoids Pseudognaphalium affine (D. Don) Anderberg Labiatae Flavonones Source classification Plants	HIV
Tsugafolin (compound 4) is a dehydroflavone with weak anti-HIV activity (IC₅₀=118 μM) and devoid cytotoxicity (<150 μM). Tsugafolin can be isolated from Vitex leptobotrys .

HY-N6808R

Rebaudioside B (Standard)	Structural Classification Trifolium hybridum L. other families Terpenoids Source classification Diterpenoids Plants Compositae	Others
Rebaudioside B (Standard) is the analytical standard of Rebaudioside B. This product is intended for research and analytical applications. Rebaudioside B is the minor constituent isolated from the leaves of Stevia rebaudiana Bertoni. Rebaudioside B tastes about 150 times sweeter than sucrose .

HY-N13182

Taxoquinone	Structural Classification Cupressaceae Terpenoids Source classification Diterpenoids Plants Metasequoia glyptostroboides Hu & W. C. Cheng	Others
Taxoquinone is an antioxidant derived from Metasequoia glyptostroboides and belongs to the diterpenoid class of compounds. At a concentration of 150 μg/mL, Taxoquinone exhibits a maximum inhibition of DPPH radicals of 81.29%, demonstrating superior antioxidant activity compared to Ascorbic acid and α-tocopherol at the same concentration .

HY-P0018

Pepstatin Maximum Cited Publications 32 Publications Verification Pepstatin A	Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields Cancer	HIV Protease Autophagy
Pepstatin (Pepstatin A) is a specific, orally active aspartic protease inhibitor produced by actinomycetes, with IC₅₀s of 4.5 nM, 6.2 nM, 150 nM, 290 nM, 520 nM and 260 nM for hemoglobin-pepsin, hemoglobin-proctase, casein-pepsin, casein-proctase, casein-acid protease and hemoglobin-acid protease, respectively. Pepstatin also inhibits HIV protease .

HY-P0018A

Pepstatin Trifluoroacetate Maximum Cited Publications 32 Publications Verification Pepstatin A Trifluoroacetate	Infection Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields	HIV Protease Autophagy
Pepstatin (Pepstatin A) Trifluoroacetate is a specific, orally active aspartic protease inhibitor produced by actinomycetes, with IC₅₀s of 4.5 nM, 6.2 nM, 150 nM, 290 nM, 520 nM and 260 nM for hemoglobin-pepsin, hemoglobin-proctase, casein-pepsin, casein-proctase, casein-acid protease and hemoglobin-acid protease, respectively. Pepstatin Trifluoroacetate also inhibits HIV protease .

HY-P0018B

Pepstatin Ammonium Maximum Cited Publications 32 Publications Verification Pepstatin A Ammonium	Infection Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields	HIV Protease Autophagy
Pepstatin (Pepstatin A) Ammonium is a specific, orally active aspartic protease inhibitor produced by actinomycetes, with IC₅₀s of 4.5 nM, 6.2 nM, 150 nM, 290 nM, 520 nM and 260 nM for hemoglobin-pepsin, hemoglobin-proctase, casein-pepsin, casein-proctase, casein-acid protease and hemoglobin-acid protease, respectively. Pepstatin Ammonium also inhibits HIV protease .

HY-W728151

3-O-Caffeoylshikimic acid	Structural Classification Livistona chinensis (Jacq.) R. Br. ex Mart. Source classification Phenols Polyphenols Palmae Plants	Endogenous Metabolite
3-O-Caffeoylshikimic acid (Compound 8) is a phenolic and can be isolated from Livistona chinensis. 3-O-Caffeoylshikimic acid is an antioxidant agent. 3-O-Caffeoylshikimic acid inhibits the proliferation of human cancer cells HepG2, HL-60, K562, and CNE-1 with IC₅₀s of 5–150 μM .

HY-N0990

1,5,15-Trimethylmorindol	Anthraquinones Source classification Morinda citrifolia Linn. Rubiaceae Plants	Others
1,5,15-Trimethylmorindol is an anthraquinone isolated from the leaves of Morinda citrifolia. 1,5,15- trimethylmorindol (25 μg/mL) does not show significant cytotoxic activity on the human T-cell leukemia cell line, Jurkat, by itself but it shows cytotoxicity (IC₅₀ 14.5-15.0 μg/mL) when combined with 0.5-1.5 μg/mL of TRAIL in the cell proliferation assay .

HY-N0460

1-Caffeoylquinic acid 1 Publications Verification	Phyllodium pulchellum (L.) Desv. Classification of Application Fields Source classification Phenols Polyphenols Plants Compositae Disease Research Fields Cancer	NF-κB
1-Caffeoylquinic acid is an effective NF-κB inhibitor, shows significant binding affinity to the RH domain of p105 with K_i of 0.002 μM and binding energy of 1.50 Kcal/mol . 1-Caffeoylquinic acid has anti-oxidative stress ability . 1-Caffeoylquinic acid inhibits PD-1/PD-L1 interact .

HY-32343

Secalciferol 4 Publications Verification (24R)-24,25-Dihydroxyvitamin D3	Structural Classification Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields Steroids	Endogenous Metabolite VD/VDR
Secalciferol ((24R)-24,25-Dihydroxyvitamin D3) is the major active metabolite of Vitamin D. Secalciferol activates vitamin D receptor (VDR) with an EC₅₀ value of 150 nM. Secalciferol is involved in a wide range of biological functions such as calcium homeostasis, cellular differentiation and proliferation processes, as well as other functions related to the immune system, which is promising for research of rickets, osteomalacia, hypercalcemia and autoimmune disorders .

HY-126634

Lyngbyatoxin B	Structural Classification Natural Products other families Source classification Plants Lyngbya majuscule	Others
Lyngbyatoxin B is a complex compound in a versatile biosynthetic pathway from the marine cyanobacterium Moorea producens. By heterologously expressing the lyngbyatoxin biosynthetic pathway in Escherichia coli, lyngbyatoxin A (25.6 mg/L) and its precursor indolactam-V (150 mg/L) were successfully produced. This approach confirmed the biosynthetic route of lyngbyatoxin and laid a chemical foundation for future pathway engineering. In addition, the successful production of lyngbyatoxin A in E. coli opens the possibility for heterologous expression and characterization of other cyanobacterial natural products.

HY-N0460R

1-Caffeoylquinic acid (Standard)	Phyllodium pulchellum (L.) Desv. Structural Classification Source classification Phenols Polyphenols Plants Compositae	NF-κB
1-Caffeoylquinic acid (Standard) is the analytical standard of 1-Caffeoylquinic acid. This product is intended for research and analytical applications. 1-Caffeoylquinic acid is an effective NF-κB inhibitor, shows significant binding affinity to the RH domain of p105 with Ki of 0.002 μM and binding energy of 1.50 Kcal/mol . 1-Caffeoylquinic acid has anti-oxidative stress ability . 1-Caffeoylquinic acid inhibits PD-1/PD-L1 interact .

HY-121197

Balanol Ophiocordin; Azepinostatin	Structural Classification Natural Products Microorganisms Source classification	MARCKS PKA PKC
Balanol (Ophiocordin; Azepinostatin) is a potent and ATP competitive PKC/PKA inhibitor against human PKC isozymes α, β-I, β-II, γ, δ, ε, η (IC₅₀s=4-9 nM) and ζ (IC₅₀=150 nM). Balanol also blocks the phosphorylation of cyclic AMP response element-binding protein (CREB) and myristoylated alanine-rich C kinase substrate (MARCKS). Balanol can be isolated from the fungus Verticillium balanoides .

HY-N0049

Nuciferine 5 Publications Verification	Structural Classification Alkaloids Aporphine Alkaloids other families Source classification Plants Isoquinoline Alkaloids	Parasite 5-HT Receptor Dopamine Receptor
Nuciferine is an antagonist at 5-HT_2A (IC₅₀=478 nM), 5-HT_2C (IC₅₀=131 nM), and 5-HT_2B (IC₅₀=1 μM), an inverse agonist at *5-HT₇* (IC₅₀=150 nM), a partial agonist at D₂ (EC₅₀=64 nM), D₅ (EC₅₀=2.6 μM) and 5-HT₆ (EC₅₀=700 nM), an agonist at 5-HT_1A (EC₅₀=3.2 μM) and D₄ (EC₅₀=2 μM) receptor.

HY-N0049R

Nuciferine (Standard)	Structural Classification Alkaloids other families Source classification Plants	5-HT Receptor Dopamine Receptor
Nuciferine (Standard) is the analytical standard of Nuciferine. This product is intended for research and analytical applications. Nuciferine is an antagonist at 5-HT_2A (IC₅₀=478 nM), 5-HT_2C (IC₅₀=131 nM), and 5-HT_2B (IC₅₀=1 μM), an inverse agonist at *5-HT₇* (IC₅₀=150 nM), a partial agonist at D₂ (EC₅₀=64 nM), D₅ (EC₅₀=2.6 μM) and 5-HT₆ (EC₅₀=700 nM), an agonist at 5-HT_1A (EC₅₀=3.2 μM) and D₄ (EC₅₀=2 μM) receptor.

HY-N0469R

L-Lysine (Standard)	Structural Classification Microorganisms Source classification Disease markers Endocrine diseases Amino acids Nervous System Disorder Endogenous metabolite	Endogenous Metabolite Virus Protease HSV
L-Lysine (Standard) is the analytical standard of L-Lysine. This product is intended for research and analytical applications. L-lysine is an essential amino acid for humans with orally activity. L-lysine can inhibit the occurrence of HSV infections and is used in herpes research. L-lysine increases calcium absorption, reduces diabetes-related diseases, improves gut health, and alleviates pancreatic inflammation. L-lysine can be used in research on metabolism, infection, and inflammation . IC₅₀ & Target:L-lysine (150 mg/kg) promotes, but not initiates, bladder cancer. The administration of L-lysine to rats submitted to colovesical cystoplasty accelerates the development of transitional metaplasia of the intestinal epithelium . L-lysine (10 mg/kg) treatment attenuates pancreatic tissue injury induced by L-arginine by inhibiting the release of the inflammatory cytokine IL-6 and enhance antioxidant activity . In Vivo:L-lysine (10?mg/kg, p.o., pre-treated or post-treated, administration duration 15 days) treatment attenuates pancreatic tissue injury induced by L-arginine by inhibiting the release of the inflammatory cytokine IL-6 and enhance antioxidant activity in acute pancreatitis mice model . L-lysine (5 or 10?mg/kg, p.o., 45 days) ameliorates sepsis-induced acute lung injury in a lipopolysaccharide (HY-D1056)-induced mouse model .

Cat. No.	Product Name	Chemical Structure

HY-146796S

15:0 Cholesteryl ester-d7
15:0 Cholesteryl ester-d₇ is deuterium labeled 15:0 Cholesteryl ester.

HY-146842S

15:0 Lyso PE-d5
15:0 Lyso PE-d₅ is deuterium labeled 15:0 Lyso PE.

HY-146854S

15:0 Lyso PG-d5
15:0 Lyso PG-d₅ is deuterium labeled 15:0 Lyso PG.

HY-146925S

15:0 Lyso PC-d5
15:0 Lyso PC-d₅ is deuterium labeled 15:0 Lyso PC.

HY-146901S

15:0 SM (d18:1/15:0)-d9
15:0 SM (d18:1/15:0)-d₉ is deuterium labeled 15:0 SM (d18:1/15:0).

HY-146774S

*14:1 cholesteryl* ester-d7**
14:1 cholesteryl ester-d₇ is deuterium labeled 14:1 cholesteryl ester.

HY-146779S

*16:1 Cholesteryl* ester-d7**
16:1 Cholesteryl ester-d₇ is deuterium labeled 16:1 Cholesteryl ester.

HY-146781S

*20:3 Cholesteryl* ester-d7**
20:3 Cholesteryl ester-d₇ is deuterium labeled 20:3 Cholesteryl ester.

HY-Y0054S

Isocyanic acid, p-tolyl ester-d7
Isocyanic acid, p-tolyl ester-d₇ is the deuterium labeled Isocyanic acid, p-tolyl ester[1].

HY-146799S

15:0-18:1-15:0 TG-d7
15:0-18:1-15:0 TG-d₇ is deuterium labeled 15:0-18:1-15:0 TG.

HY-146913S

15:0-18:1-15:0 TG-d5
15:0-18:1-15:0 TG-d₅ is deuterium labeled 15:0-18:1-15:0 TG.

HY-10844S1

Pretomanid-d5
Pretomanid-d₅ is deuterated labeled Pretomanid (HY-10844). Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 μg/mL.

HY-W010708S

Cholesteryl palmitate-d9
Cholesteryl palmitate-d₉ is the deuterium labeled Cholesteryl palmitate. Cholesteryl palmitate is a useful prognostic biomarker for chronic interstitial pneumonia (CIP).

HY-107327S

Carazolol-d7
Carazolol-d₇ is the deuterium labeled Carazolol[1].

HY-N0006S

Demethoxycurcumin-d7
Demethoxycurcumin-d₇ is the deuterium labeled Demethoxycurcumin. Demethoxycurcumin(Curcumin II), a major active curcuminoid, possess anti-inflammatory properties; also exert cytotoxic effects in human cancer cells via induction of apoptosis.

HY-113217S

Cholesteryl oleate-d7
Cholesteryl oleate-d₇ is deuterium labeled Cholesteryl oleate. Cholesteryl oleate is an esterified form of Cholesterol. Cholesteryl oleate can be used in the generation of solid lipid nanoparticle (SLN, a nanoparticle-based method for gene therapy)[1

HY-W010708S1

Cholesteryl palmitate-d7
Cholesteryl palmitate-d₇ is deuterium labeled Cholesteryl palmitate. Cholesteryl palmitate is a useful prognostic biomarker for chronic interstitial pneumonia (CIP)[1].

HY-66005S2

Acetaminophen-d7
Acetaminophen-d₇ is the deuterium labeled Acetaminophen. Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM; is a widely used antipyretic and analgesic agent. Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor.

HY-B0389S6

D-Glucose-d7
D-Glucose-d₇7 is the deuterium labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].

HY-107352S

Fosfenopril-d7
Fosfenopril-d₇ is deuterium labeled Fosfenopril.

HY-D0711S2

Indocyanine green-d7
Indocyanine green-d7 (Foxgreen-d7) is the deuterium labeled Indocyanine green (HY-D0711). Indocyanine green is a low toxicic fluorescent agent that has been widely used in medical diagnostics, such as determining cardiac output, hepatic function, and liver blood flow, and for ophthalmic angiography .

HY-146795S

15:0-18:1 DG-d7
15:0-18:1 DG-d₇ is deuterium labeled 15:0-18:1 DG.

HY-113217S1

Cholesteryl oleate-d7-1
Cholesteryl oleate-d₇-1 is deuterium labeled Cholesteryl oleate. Cholesteryl oleate is an esterified form of Cholesterol. Cholesteryl oleate can be used in the generation of solid lipid nanoparticle (SLN, a nanoparticle-based method for gene therapy)

HY-12057S1

Vemurafenib-d7
Vemurafenib-d₇ is deuterium labeled Vemurafenib. Vemurafenib (PLX4032) is a first-in-class, selective, potent inhibitor of B-RAF kinase, with IC50s of 31 and 48 nM for RAFV600E and c-RAF-1, respectively[1][4]. Vemurafenib induces cell autophagy[5].

HY-Y0376S

DMPA-d7
DMPA-d₇ is the deuterium labeled DMPA[1].

HY-Y1298S1

Methyl acetylacetate-d3
Methyl acetylacetate-d₃ (Acetoacetate methyl ester-d₃) is a deuterium labeled Methyl acetylacetate (HY-Y1298). Methyl acetylacetate is an endogenous metabolite .

HY-135328S

Norverapamil-d7
Norverapamil-d₇ is a deuterium labeled Norverapamil ((±)-Norverapamil). Norverapamil, an N-demethylated metabolite of Verapamil, is a L-type calcium channel blocker and a P-glycoprotein (P-gp) function inhibitor[1][2].

HY-17025S

Rifabutin-d7
Rifabutin-d₇ is the deuterium labeled Rifabutin. Rifabutin (Ansamycin) is a semisynthetic ansamycin antibiotic with potent antimycobacterial properties. Rifabutin inhibits DNA-dependent RNA polymerase.

HY-107855S

DL-Mevalonolactone-d7
DL-Mevalonolactone-d₇ is the deuterium labeled DL-Mevalonolactone. DL-Mevalonolactone ((±)-Mevalonolactone) is the δ-lactone form of mevalonic acid, a precursor in the mevalonate pathway. DL-Mevalonolactone (Mevalonolactone) decreases mitochondrial membrane potential (∆Ψm), NAD(P)H content and the capacity to retain Ca2+ in the brain, besides inducing mitochondrial swelling[1][2].

HY-41700S3

D-Alanine-d7
D-Alanine-d₇ is the deuterium labeled D-Alanine. D-Alanine is a weak GlyR (inhibitory glycine receptor) and PMBA agonist, with an EC50 of 9 mM for GlyR.

HY-30237S

(R)-Roscovitine-d7
(R)-Roscovitine-d₇ (Seliciclib-d₇; CYC202-d₇) is deuterium-labeled (R)-Roscovitine (HY-30237) .

HY-B0679S

Lubiprostone-d7
Lubiprostone-d₇ (RU-0211-d7) is the deuterium labeled Lubiprostone. Lubiprostone (RU0211) is a gastrointestinal agent used for the treatment of idiopathic chronic constipation[1][2].

HY-50898S1

Lapatinib-d7 dihydrochloride
Lapatinib-d₇ (dihydrochloride) is the deuterium labeled Lapatinib dihydrochloride. Lapatinib (GW572016) dihydrochloride is a potent inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively[1].

HY-12296S

Navtemadlin-d7
Navtemadlin-d₇ is the deuterium labeled Navtemadlin. Navtemadlin (AMG 232) is a potent, selective and orally available inhibitor of p53-MDM2 interaction, with an IC50 of 0.6 nM. Navtemadlin binds to MDM2 with a Kd of 0.045 nM[1][2].

HY-13720AS

Pergolide-d7 mesylate
Pergolide-d₇ (mesylate) is the deuterium labeled Pergolide mesylate. Pergolide mesylate (Pergolide methanesulfonate), an Ergoline derivative, is a potent and orally active dopamine D1 and D2 receptors agonist. Pergolide mesylate can be used for Parkinson's disease and hyperprolactinaemia research[1][2].

HY-N2334AS

Glycochenodeoxycholic acid-d7 sodium

Glycochenodeoxycholic acid-d₇ (sodium) is the deuterium labeled Glycochenodeoxycholic acid (sodium salt). Glycochenodeoxycholic acid sodium salt (Chenodeoxycholylglycine sodium salt) is a bile acid formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. Glycochenodeoxycholic acid sodium salt (Chenodeoxycholylglycine sodium salt) induces hepatocyte apoptosis[1][2].

HY-12785S1

Albendazole sulfoxide-d7
Albendazole sulfoxide-d₇ is the deuterium labeled Albendazole sulfoxide. Albendazole sulfoxide (Ricobendazole), the main active metabolite of Albendazole, exhibits anti-parasite effect against Echinococcus multilocularis Metacestodes[1].

HY-14268S1

Febuxostat-d7
Febuxostat-d₇ is deuterium labeled Febuxostat. Febuxostat (TEI 6720) is selective xanthine oxidase inhibitor with a Ki of 0.6 nM[1].

HY-B1674S4

(±)-Leucine-d7
(±)-Leucine-d₇ is the deuterium labeled (±)-Leucine. (±)-Leucine (DL-Leucine), an isomer of Leucine, chemosterilant and dietary additive. (±)-Leucine inhibits growth of Escherichia coli HfrH by 92.08%[1].

HY-N0650S11

L-Serine-d7
L-Serine-d₇ is the deuterium labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-N7745S

Glucosylsphingosine-d7
Glucosylsphingosine-d₇ is deuterium labeled Glucosylsphingosine.

HY-135853S

Molnupiravir-d7

Molnupiravir-d₇ is the deuterium labeled Molnupiravir. Molnupiravir (EIDD-2801) is an orally bioavailable prodrug of the ribonucleoside analog EIDD-1931. Molnupiravir has broad spectrum antiviral activity against influenza virus and multiple coronaviruses, such as SARS-CoV-2, MERS-CoV, SARS-CoV. Molnupiravir has the potential for the research of COVID-19, and seasonal and pandemic influenza[1][2].

HY-14275S1

Verapamil-d7
Verapamil-d₇ is the deuterium labeled Verapamil (HY-14275). Verapamil ((±)-Verapamil) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor. Verapamil also inhibits CYP3A4. Verapamil has the potential for high blood pressure, heart arrhythmias and angina research .

HY-B0202S3

Irbesartan-d7
Irbesartan-d₇ is deuterated labeled Irbesartan (HY-B0202). Irbesartan (SR-47436) is an orally active Ang II type 1 (AT1) receptor blocker (ARB). Irbesartan can relax the blood vessels, low blood pressure and increase the supply of blood and oxygen to the heart. Irbesartan can be used for the research of high blood pressure, heart failure, and diabetic kidney disease .

HY-B0202AS

Irbesartan-d7 hydrochloride

Irbesartan-d₇ hydrochloride is deuterated labeled Irbesartan hydrochloride (HY-B0202A). Irbesartan (SR-47436) hydrochloride is an orally active Ang II type 1 (AT1) receptor blocker (ARB). Irbesartan hydrochloride can relax the blood vessels, low blood pressure and increase the supply of blood and oxygen to the heart. Irbesartan hydrochloride can be used for the research of high blood pressure, heart failure, and diabetic kidney disease .

HY-B0161AS1

Duloxetine-d7 hydrochloride
Duloxetine-d7 hydrochloride ((S)-Duloxetine-d7 hydrochloride) is the deuterium labeled Duloxetine hydrochloride (HY-B0161A). Duloxetine hydrochloride ((S)-Duloxetine hydrochloride) is a serotonin-norepinephrine reuptake inhibitor (SNRI) with a K_i of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD) .

HY-101047S

D-erythro-Sphingosine-d7
D-erythro-Sphingosine-d₇ is the deuterium labeled D-erythro-Sphingosine. D-erythro-Sphingosine (Erythrosphingosine) is a very potent activator of p32-kinase with an EC50 of 8 μM, and inhibits protein kinase C (PKC). D-erythro-Sphingosine (Erythrosphingosine) is also a PP2A activator[1][2][3][4].

HY-B0763S2

Ibudilast-d7-1

Ibudilast-d₇-1 is the deuterium labeled Ibudilast[1]. Ibudilast (KC-404;AV-411;MN-166) is a cyclic AMP phosphodiesterase (PDE) inhibitor. Ibudilast has platelet anti-aggregatory effects. Ibudilast can be used for the research of asthma for its inhibitory effects on tracheal smooth muscle contractility. Ibudilast may be a useful neuroprotective and anti-dementia agent counteracting neurotoxicity in activated microglia[2].

HY-14291S1

Vildagliptin-d7
Vildagliptin-d₇ is deuterium labeled Vildagliptin. Vildagliptin (LAF237) is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC50 of 3.5 nM in human Caco-2 cells. Vildagliptin possesses excellent oral bioavailability and potent antihyperglycemic activity[1].

HY-B1178S2

(Rac)-Cotinine-d7
(Rac)-Cotinine-d₇ is deuterium labeled Cotinine.

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks