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By Research Areas:	Cancer (1021) Cardiovascular Disease (594) Endocrinology (158) Infection (349) Inflammation/Immunology (522) Metabolic Disease (174) Neurological Disease (783)
Click Chemistry:	TCO (1) Labeling and Fluorescence Imaging (1) PROTAC Synthesis (1) Azide (15) Tetrazine (1) Alkynes (10)
Oligonucleotides:	Release-retarding Agents (1) Nucleotides and their Analogs (1) Nucleosides and their Analogs (1) Thickeners (1) Nucleoside Phosphoramidites (2) Aptamers (7) Emulsifiers (1) Polymers (7)

3029

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

129

Biochemical Assay Reagents

242

Peptides

MCE Kits

117

Inhibitory Antibodies

262

Natural
Products

225

Isotope-Labeled Compounds

Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-116767

BLT-1 3 Publications Verification block lipid transport-1	HCV	Metabolic Disease Inflammation/Immunology
BLT-1, a thiosemicarbazone copper chelator, is a selective scavenger receptor B, type 1 (SR-BI) inhibitor. BLT-1 inhibits the transfer of lipids between high-density lipoproteins (HDL) and cells mediated by SR-BI. BLT-1 is a potent HCV entry inhibitor .

HY-52121

Windaus ketone	Others	Others
Windaus ketone is a VD building blocker.

HY-145482

W36017	Drug Metabolite	Neurological Disease
W3601 is the impurity of Lidocaine. W3601 exhibits nerve blocking activity with the pK_a of 7.4 .

HY-B1304A

(+)-Sparteine sulfate pentahydrate 1 Publications Verification (+)-Lupinidine sulfate pentahydrate	nAChR	Neurological Disease
(+)-sparteine (sulfate pentahydrate) is a ganglionic blocking agent. (+)-Sparteine competitively blocks nicotinic ACh receptor in the neurons .

HY-12515A

Nicardipine hydrochloride 4 Publications Verification YC-93	Calcium Channel Autophagy	Cardiovascular Disease Neurological Disease Cancer
Nicardipine hydrochloride (YC-93) is a calcium channel blocker with an IC₅₀ of 1 μM for blocking cardiac calcium channels. Nicardipine hydrochloride acts as an agent for chronic stable angina and for controlling blood pressure .

HY-116194

NaV1.7 blocker-801	Sodium Channel	Neurological Disease
NaV1.7 blocker-801 is a NaV1.7 channel blocker that can be used in the study of neurological diseases .

HY-E70402

*Double-block* Hotstart Taq DNA Polymerase**	Biochemical Assay Reagents	Others
that can be used in molecular biology to amplify DNA sequences through the polymerase chain reaction (PCR) .

HY-105154A

Proxodolol	Adrenergic Receptor	Cardiovascular Disease
Proxodolol is a β-adrenergic receptor blocker. Proxodolol can be used for the study of arterial hypertension .

HY-N9949

Sparteine Lupinidine	nAChR	Neurological Disease
Sparteine (Lupinidine) is an alkaloid compound derived from leguminous plants and can act as a ganglionic blocker. Sparteine competitively inhibits the activity of the neuronal nicotinic acetylcholine receptor (nACh receptor) .

HY-162111

SARS-CoV-2-IN-73	SARS-CoV	Infection
SARS-CoV-2-IN-73 (compound 4) is a SARS-CoV-2 RNA-dependent RNA polymerase (RdRp) blocker .

HY-12515

Nicardipine 4 Publications Verification YC-93 free base	Calcium Channel	Cardiovascular Disease Neurological Disease Cancer
Nicardipine (YC-93 free base) is a calcium channel blocker with an IC₅₀ of 1 μM for blocking cardiac calcium channels. Nicardipine acts as an agent for chronic stable angina and for controlling blood pressure .

HY-W020030

4-Amino-3,6-disulfonaphthalic anhydride dipotassium	Fluorescent Dye	Others
4-Amino-3,6-disulfonaphthalic anhydride dipotassium is a building block that can be used to systhese a useful dye for biological research purposes.

HY-W002105

2,5-Furandicarboxylic acid 1 Publications Verification	Endogenous Metabolite	Others
2,5-Furandicarboxylic acid, detected in human urine, is an important renewable biotechnological building block because it serves as an environmentally friendly substitute for terephthalic acid in the production of polyesters .

HY-B1007

Butacaine 2 Publications Verification	Sodium Channel Others	Neurological Disease
Butacaine is a reversible nerve conduction blocker. Butacaine acts on the nervous system and nerve fibers, can cause both sensory and motor paralysis. Butacaine inhibits the NavBh currents .

HY-W018801

5-Nitroisoquinoline	Biochemical Assay Reagents	Others
5-Nitroisoquinoline (5NIQ) has the molecular formula C₉H₆N₂O₂ and can be used as a molecular building block .

HY-W007719

7-Methylisatin	Biochemical Assay Reagents	Others
7-Methylisatin is a derivative of Isatin (HY-Y0265) and can be utilized as a molecular block .

HY-103067

A1899 S20951	Potassium Channel	Cardiovascular Disease Neurological Disease
A1899 is a potent and highly selective blocker of the K_2P channel TASK-1. A1899 has IC₅₀ values of 35.1 nM and 7 nM for TASK-1 channels expressed in oocytes and CHO cells, respectively. A1899 is also an I_Kur blocker that can be used for the research of cardiovascular diseases .

HY-W270730

Dec-2-yn-1-ol	Biochemical Assay Reagents	Cancer
Dec-2-yn-1-ol is a molecular block that can be used to synthesize Dec-9-yn-1-ol .

HY-162549

CPK20	Potassium Channel	Neurological Disease
CPK20 is a potent and highly selective KCNT1 channel blocker, and CPK20 can be used in the study of epilepsy .

HY-12515AS

Nicardipine-d3 hydrochloride YC-93-d₃	Calcium Channel	Neurological Disease
Nicardipine-d₃ (hydrochloride) (YC-93 D3) is the deuterium labeled Nicardipine hydrochloride. Nicardipine hydrochloride is a calcium channel blocker with an IC50 of 1 μM for blocking cardiac calcium channels. Nicardipine hydrochloride acts as an agent for chronic stable angina and for controlling blood pressure[1].

HY-12515AS2

Nicardipine-d4 hydrochloride YC-93-d₄	Autophagy Calcium Channel Isotope-Labeled Compounds	Neurological Disease Cancer
Nicardipine-d₄ hydrochloride is deuterated labeled Nicardipine hydrochloride (HY-12515A). Nicardipine hydrochloride (YC-93) is a calcium channel blocker with an IC₅₀ of 1 μM for blocking cardiac calcium channels. Nicardipine hydrochloride acts as an agent for chronic stable angina and for controlling blood pressure .

HY-12515AR

Nicardipine hydrochloride (Standard)	Calcium Channel Autophagy	Neurological Disease Cancer
Nicardipine (hydrochloride) (Standard) is the analytical standard of Nicardipine (hydrochloride). This product is intended for research and analytical applications. Nicardipine hydrochloride (YC-93) is a calcium channel blocker with an IC₅₀ of 1 μM for blocking cardiac calcium channels. Nicardipine hydrochloride acts as an agent for chronic stable angina and for controlling blood pressure .

HY-164290

Rhodady C10	Dynamin	Infection Neurological Disease
Rhodady C10 (Compound C10) is a dynamin I GTPase inhibitor. Rhodady C10 blocks receptor-mediated endocytosis (IC₅₀: 7 μM). Dynamin is involved in clathrin-independent endocytosis, phagocytosis, and caveolae internalization .

HY-B1700B

(S,S)-Mivacurium dichloride	Others	Neurological Disease
(S,S)-Mivacurium dichloride (Compound 29a) is a neuromuscular blocking agent and causes muscle relaxation .

HY-105562

Nadoxolol	Adrenergic Receptor	Cardiovascular Disease
Nadoxolol is a non-selective β-adrenaline receptor blocker that can be used in the study of arrhythmias. .

HY-165544

Decamethonium chloride	Others	Neurological Disease
Decamethonium chloride is a depolarizing neuromuscular blocking agent that can be used to study the mechanism of action of muscle relaxants .

HY-125079

DSP-2230	Sodium Channel	Cardiovascular Disease Neurological Disease
DSP-2230 is a selective Nav1.7/Nav1.8 blocker, can be used to improve neuropathic pain .

HY-20003

(-)-Corey lactone benzoate	Others	Others
(-)-Corey lactone benzoate is a building block in the chemical synthesis of corey aldehyde .

HY-19662

Cronidipine LF2-0254	Calcium Channel	Cardiovascular Disease
Cronidipine (LF2-0254) is a Calcium Channel blocker. Cronidipine can be used in cardiovascular disease related research .

HY-132996

4-Isothiocyanatophenyl α-D-Mannopyranoside	Others	Others
4-Isothiocyanatophenyl α-D-Mannopyranoside, an organic isothiocyanate, is a building block and reagent which is used for preparing neoglycoproteins .

HY-120644

BMS-919373	Others	Cardiovascular Disease
BMS-919373 is a selective, potent I_Kur current blocker. BMS-919373 can be used for the research of cardiovascular diseases .

HY-126005

VGSC blocker-1	Sodium Channel	Cancer
VGSC blocker-1 is a potent and small molecule blocker of neonatal isoform of the VGSC subtype, Nav1.5 (nNav1.5). VGSC blocker-1 blocks INa peak currents 34.9% at 1 μM and inhibits cell invasion 0.3% at 1 μM in human breast cancer cell line MDA-MB-231, without affecting the cell viability .

HY-N7700

Guluronic acid G2013	Others	Inflammation/Immunology
Guluronic acid (G2013), one of the organic building blocks of hyaluronic acid, is a nonsteroidal anti-inflammatory agent has favorable anti-inflammatory effect .

HY-W012618

1-Phenyl-1-propanol	Others	Others
1-Phenyl-1-propanol is used as a chiral building block and synthetic intermediate in the pharmaceutical industries. 1-Phenyl-1-propanol is an intermediate of anti-depressant agent Fluoxetine .

HY-P1440

BeKm-1	Potassium Channel	Cardiovascular Disease
BeKm-1 is a HERG (human ether-a-go-go-related gene) blocking compound. BeKm-1 can be used for the research of heart disease .

HY-139818

Mal-PEG-PLA (PEG MW 3000 & PLA MW 70,000)	Biochemical Assay Reagents	Others
Mal-PEG-PLA (PEG MW 3000 & PLA MW 70,000) is a block copolymer, which can be used to preparenanoparticles and micelles for targeted drug delivery .

HY-141468

β-Chlornaltrexamine dihydrochloride β-CNA dihydrochloride	Opioid Receptor	Neurological Disease
β-Chlornaltrexamine dihydrochloride (β-CNA dihydrochloride) is a potent long-term opioid receptor blocker. β-Chlornaltrexamine dihydrochloride can effectively block the inhibitory effect of κ opioid receptor agonists on dopamine release. β-Chlornaltrexamine dihydrochloride can be used to study the mechanism of pain perception .

HY-16953

JNJ 303 1 Publications Verification	Potassium Channel	Cardiovascular Disease Neurological Disease
JNJ-303 is a specific delayed rectifier Kv blocker. JNJ 303 can potent block I_Ks with an IC₅₀ value of 64 nM. JNJ-303 can be used for the research of diabetes, obesity and central nervous system .

HY-P2791

Tertiapin (reduced)	Potassium Channel	Neurological Disease Inflammation/Immunology
Tertiapin (reduced) is a kind of synthesis of melittin, its Cys3-Cys14 and Cys5-Cys18 between containing a disulfide bond. Tertiapin (reduced) is a kind of inward rectifier potassium channels blockers, can block the activity of calcium activates large conductance potassium channels. Tertiapin (reduced) can be used for research in diseases such as rheumatoid arthritis and multiple sclerosis .

HY-139819

MPEG-PLA (PEG MW 3000 & PLA MW 50,000)	Biochemical Assay Reagents	Others
MPEG-PLA (PEG MW 3000 & PLA MW 50,000) is a block copolymer, which can be used to preparenanoparticles for targeted drug delivery .

HY-D0068

DEAC, SE 7-Diethylaminocoumarin-3-carboxylic acid, SE	Fluorescent Dye	Others
DEAC, SE (7-Diethylaminocoumarin-3-carboxylic acid, SE) is an excellent blue fluorescent building block for labeling amine-containing biomolecules.

HY-108247

Guanethidine sesquisulfate	Adrenergic Receptor	Cardiovascular Disease Neurological Disease
Guanethidine sesquisulfate, an antihypertensive agent, is an adrenergic neurone blocking agent. Guanethidine sesquisulfate enters noradrenergic nerve terminals by the neuronal amine carrier .

HY-W344044

Levomepromazine maleate Methotrimeprazine maleate	Others	Neurological Disease
Levomepromazine maleate (Methotrimeprazine maleate) functions as a sedative and represents a significant active pharmaceutical ingredient. As a typical N-substituted phenothiazine antipsychotic, Levomepromazine maleate is capable of blocking multiple receptors. Levomepromazine maleate finds its application in the research of schizophrenia .

HY-102032

Butyryltimolol	Adrenergic Receptor	Endocrinology
Butyryltimolol, an effective precursor of Timolol, improves the corneal penetration of Timolol . Butyryltimolol is a β-adrenergic blocker .

HY-101436

Sematilide CK-1752	Potassium Channel	Cardiovascular Disease
Sematilide (CK-1752) is a selective I_Kr channel blocker. Sematilide causes a concentration-dependent inhibition of the delayed rectifier K ⁺ current (IC₅₀=25 μM). Sematilide is a class III antiarrhythmic agent .

HY-101436A

Sematilide hydrochloride CK-1752 hydrochloride	Potassium Channel	Cardiovascular Disease
Sematilide hydrochloride (CK-1752 hydrochloride) is a selective I_Kr channel blocker. Sematilide causes a concentration-dependent inhibition of the delayed rectifier K ⁺ current (IC₅₀=25 μM). Sematilide is a class III antiarrhythmic agent .

HY-106682

Falipamil AQ-A 39	Calcium Channel	Cardiovascular Disease
Falipamil (AQ-A 39), a calcium channel blocker, is a bradycardic agent. The bradycardic effect results from a reduction in the diastolic depolarization rate and a prolongation of the action potential duration .

HY-B0997

Hydroquinidine Dihydroquinidine; (+)-Hydroquinidine; Hydroconquinine	Others	Cardiovascular Disease Cancer
Hydroquinidine (Dihydroquinidine) is a potent ion channel blocker, which exhibits strong anti-cancer activity on colon, pancreatic, and hepatocellular cancer cells. Hydroquinidine prolongs the QT interval and has antiarrhythmic efficacy .

HY-W351340

4-(Benzyloxy)-2-nitrophenol	Fluorescent Dye	Others
4-(Benzyloxy)-2-nitrophenol is a synthetic building block that can be used in the synthesis of fluorescent ion indicators .

HY-102032A

(RS)-Butyryltimolol	Adrenergic Receptor	Others
(RS)-Butyryltimolol is the racemate of Butyryltimolol. Butyryltimolol, an effective proagent of Timolol, improves the corneal penetration of Timolol . Butyryltimolol is a β-adrenergic blocker .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B1304A

(+)-Sparteine sulfate pentahydrate 1 Publications Verification (+)-Lupinidine sulfate pentahydrate	Alkaloids Piperidine Alkaloids other families Source classification Plants	nAChR
(+)-sparteine (sulfate pentahydrate) is a ganglionic blocking agent. (+)-Sparteine competitively blocks nicotinic ACh receptor in the neurons .

HY-W002105

2,5-Furandicarboxylic acid 1 Publications Verification	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
2,5-Furandicarboxylic acid, detected in human urine, is an important renewable biotechnological building block because it serves as an environmentally friendly substitute for terephthalic acid in the production of polyesters .

HY-B0997

Hydroquinidine Dihydroquinidine; (+)-Hydroquinidine; Hydroconquinine	Cardiovascular Disease Alkaloids Structural Classification Classification of Application Fields Source classification Rubiaceae Cinchona calisaya Wedd. Quinoline Alkaloids Plants Disease Research Fields	Others
Hydroquinidine (Dihydroquinidine) is a potent ion channel blocker, which exhibits strong anti-cancer activity on colon, pancreatic, and hepatocellular cancer cells. Hydroquinidine prolongs the QT interval and has antiarrhythmic efficacy .

HY-N8404

Chlorahololide C	Structural Classification Classification of Application Fields Chloranthus holostegius (Hand.-Mazz.) Pei et Shan Terpenoids Sesquiterpenes Source classification Chloranthaceae Plants Inflammation/Immunology Disease Research Fields	Potassium Channel
Chlorahololide C, a lindenane sesquiterpenoid dimer, is isolated from Chloranthus holostegius. Chlorahololide C is a potent and selective potassium channel blocker, with an IC₅₀ of 3.6 μM .

HY-N0747

Oxypeucedanin	Cardiovascular Disease Structural Classification Chrysanthemum × morifolium (Ramat.) Hemsl. Classification of Application Fields Source classification Coumarins Phenylpropanoids Umbelliferae Plants Disease Research Fields	Potassium Channel Apoptosis
Oxypeucedanin is a furocoumarin derivative isolated from Angelica dahurica. Oxypeucedanin is a selective open-channel blocker, inhibits the hKv1.5 current with an IC₅₀ value of 76 nM. Oxypeucedanin prolongs cardiac action potential duration (APD), is a potential antiarrhythmic agent for atrial fibrillation . Oxypeucedanin induces cell apoptosis through inhibition of cancer cell migration .

HY-125818

Cytidine-5'-triphosphate 2 Publications Verification Cytidine triphosphate; 5'-CTP	Infection Structural Classification Natural Products Human Gut Microbiota Metabolites Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Cancer	DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Endogenous Metabolite
Cytidine 5′-triphosphate (Cytidine triphosphate; 5'-CTP) is a nucleoside triphosphate and serves as a building block for nucleotides and nucleic acids, lipid biosynthesis. Cytidine triphosphate synthase can catalyze the formation of cytidine 5′-triphosphate from uridine 5′-triphosphate (UTP). Cytidine 5′-triphosphate is an essential biomolecule in the de novo pyrimidine biosynthetic pathway in T. gondii .

HY-W008350

(+)-Sparteine 1 Publications Verification Pachycarpine	Alkaloids Piperidine Alkaloids Structural Classification other families Source classification Plants	nAChR
(+)-Sparteine is a natural alkaloid acting as a ganglionic blocking agent. (+)-Sparteine competitively blocks nicotinic ACh receptor in the neurons.

HY-N9949

Sparteine Lupinidine	Structural Classification Alkaloids Piperidine Alkaloids Source classification Plants Fabaceae Lupinus sulphureus Douglas	nAChR
Sparteine (Lupinidine) is an alkaloid compound derived from leguminous plants and can act as a ganglionic blocker. Sparteine competitively inhibits the activity of the neuronal nicotinic acetylcholine receptor (nACh receptor) .

HY-N0747R

Oxypeucedanin (Standard)	Structural Classification Chrysanthemum × morifolium (Ramat.) Hemsl. Source classification Coumarins Phenylpropanoids Umbelliferae Plants	Potassium Channel Apoptosis
Oxypeucedanin (Standard) is the analytical standard of Oxypeucedanin. This product is intended for research and analytical applications. Oxypeucedanin is a furocoumarin derivative isolated from Angelica dahurica. Oxypeucedanin is a selective open-channel blocker, inhibits the hKv1.5 current with an IC₅₀ value of 76 nM.?Oxypeucedanin prolongs cardiac action potential duration (APD), is a potential antiarrhythmic agent for atrial fibrillation . Oxypeucedanin induces cell?apoptosis through inhibition of cancer cell migration .

HY-W035904

Tropone Cycloheptatrienone	Structural Classification other families Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Plants Disease Research Fields	Others
Tropone is a building block in the chemical synthesis .

HY-14589

Chrysin 5+ Cited Publications 5,7-Dihydroxyflavone	Structural Classification Classification of Application Fields Flavones Source classification Plants Oroxylum indicum (Linn.) Bentham ex Kurz Endogenous metabolite Human Gut Microbiota Metabolites Flavonoids Phenols Polyphenols Bignoniaceae Disease Research Fields Cancer	Estrogen Receptor/ERR
Chrysin is one of the most well known estrogen blockers.

HY-N0221

Daurisoline 2 Publications Verification (R,R)-Daurisoline	Alkaloids Structural Classification other families Classification of Application Fields Source classification Phenols Polyphenols Plants Isoquinoline Alkaloids Disease Research Fields Cancer	Autophagy Potassium Channel
Daurisoline is a bis-benzylisoquinoline alkaloid that can be isolated from Menispermum dauricum and Rhizoma Menispermi. Daurisoline exerts a blocking effect on hERG and has antiarrhythmic effects. Daurisoline is a potent autophagy blocker that can be used for the research of cancer .

HY-Y0771

3,4-Dimethoxyphenylacetic acid	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
3,4-Dimethoxyphenylacetic acid is a building block in the chemical synthesis.

HY-W011683

2'-Deoxyadenosine monohydrate	Natural Products Microorganisms Source classification Other Diseases Disease Research Fields	Endogenous Metabolite
2'-Deoxyadenosine monohydrate is a deoxyribonucleoside. A building block in the chemical synthesis.

HY-B1167

Ajmaline Cardiorythmine; (+)-Ajmaline	Apocynaceae Cardiovascular Disease Alkaloids Piperidine Alkaloids Structural Classification Rauvolfia serpentina Classification of Application Fields Source classification Plants Disease Research Fields Indole Alkaloids	Sodium Channel
Ajmaline (Cardiorythmine) is a sodium channel blocking, class 1A anti-arrhythmic agent. Ajmaline blocks HERG currents with an IC₅₀ of 1 μM in HEK cells and 42.3 μM in Xenopus oocytes. Ajmaline can be used for the research of the ventricular tachyarrhythmia .

HY-B0426A

Olopatadine hydrochloride ALO4943A; KW4679	Structural Classification Alkaloids Classification of Application Fields Ketones, Aldehydes, Acids Other Alkaloids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Histamine Receptor Endogenous Metabolite
Olopatadine hydrochloride (ALO4943A) is a histamine blocker used to treat allergic conjunctivitis.

HY-B2136

Tannic acid 3 Publications Verification	Structural Classification Classification of Application Fields Anti-aging Source classification Plants Liliaceae Ketones, Aldehydes, Acids Phenols Polyphenols Polygonatum odoratum (Mill.) Druce Inflammation/Immunology Disease Research Fields Cancer	Potassium Channel
Tannic acid is a novel hERG channel blocker with IC₅₀ of 3.4 μM.

HY-124143

Isoguanine	Structural Classification Natural Products Microorganisms Classification of Application Fields Croton tiglium Linn. Source classification Other Diseases Euphorbiaceae Plants Disease Research Fields	Nucleoside Antimetabolite/Analog
Isoguanine is a purine base that is an isomer of Guanine. A building block in organic synthesis.

HY-W002343

3,5-Dimethylbenzaldehyde	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
3,5-Dimethylbenzaldehyde is a building block in the chemical synthesis .

HY-Y0511

N-Methylsarcosine 1 Publications Verification Dimethylglycine; DMG; N,N-Dimethylglycine	Structural Classification Microorganisms Other disease Classification of Application Fields Source classification Disease markers Other Diseases Amino acids Endogenous metabolite Disease Research Fields	Endogenous Metabolite
N-Methylsarcosine is an amino acid building block for protein, found in a small amount in the body.

HY-N9374

Bufotenidine	Alkaloids Structural Classification Animals Source classification Indole Alkaloids	5-HT Receptor
Bufotenidine, a natural indole alkaloid, is a blocking agent of the tryptaminic receptors .

HY-W008393

(-)-Corey lactone diol	Classification of Application Fields Other Diseases Disease Research Fields	Others
(-)-Corey lactone diol is a reduced version of corey aldehyde. A building block in the chemical synthesis.

HY-Y0252

L-Proline 4 Publications Verification	Structural Classification Microorganisms Classification of Application Fields Source classification Other Diseases Amino acids Endogenous metabolite Disease Research Fields	Endogenous Metabolite
L-Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins.

HY-B1304

(-)-Sparteine sulfate pentahydrate (-)-Lupinidine sulfate pentahydrate	Cardiovascular Disease Classification of Application Fields Disease Research Fields	Sodium Channel
(-)-Sparteine sulfate pentahydrate ((-)-Lupinidine sulfate pentahydrate) is a class 1a antiarrhythmic agent and a sodium channel blocker.

HY-N2131

Isosakuranetin 1 Publications Verification	Structural Classification Flavonoids Classification of Application Fields Flavanols Rutaceae Other Diseases Plants Citrus bergamia Disease Research Fields	Others
Isosakuranetin is a flavanone flavonoid which can be found in the fruit of Citrus bergamia. Isosakuranetin is a TRPM3 Blocker.

HY-40135

L-Hydroxyproline (2S,4R)-4-Hydroxypyrrolidine-2-carboxylic acid	Alkaloids Structural Classification Immune System Disorder Pyrrole Alkaloids Classification of Application Fields Source classification Disease markers Other Diseases Endocrine diseases Nervous System Disorder Endogenous metabolite Disease Research Fields	Endogenous Metabolite
L-Hydroxyproline, one of the hydroxyproline (Hyp) isomers, is a useful chiral building block in the production of many pharmaceuticals.

HY-Y0479

L-Lactic acid 5 Publications Verification (S)-2-Hydroxypropanoic acid	Structural Classification Classification of Application Fields Source classification Endocrine diseases Endogenous metabolite Infection Immune System Disorder Microorganisms Ketones, Aldehydes, Acids Disease markers Nervous System Disorder Disease Research Fields Cardiovascular System Disorder	Bacterial Endogenous Metabolite Antibiotic
L-Lactic acid is a buildiing block which can be used as a precursor for the production of the bioplastic polymer poly-lactic acid.

HY-W012815

3-Methylcatechol	Structural Classification Microorganisms Classification of Application Fields Source classification Other Diseases Phenols Polyphenols Disease Research Fields	Others
3-Methylcatechol is a building block in the chemical synthesis produced by Pseudomonas putida MC2 .

HY-N0219

Bicuculline 20+ Cited Publications (+)-Bicuculline; d-Bicuculline	Alkaloids Structural Classification Source classification Lamprocapnos spectabilis (L.) Fukuhara Plants Isoquinoline Alkaloids Papaveraceae	GABA Receptor
Bicuculline ((+)-Bicuculline) is A competing neurotransmitter GABA_A receptor antagonist (IC₅₀=2 μM). Bicuculline also blocks Ca ²⁺ activating potassium (SK) channels and subsequently blocks slow post-hyperpolarization (slow AHP). Bicuculline has anticonvulsant activity. Bicuculline can be used to induce seizures in mice .

HY-B1167R

Ajmaline (Standard)	Apocynaceae Alkaloids Piperidine Alkaloids Structural Classification Rauvolfia serpentina Source classification Plants Indole Alkaloids	Sodium Channel
Ajmaline (Standard) is the analytical standard of Ajmaline. This product is intended for research and analytical applications. Ajmaline (Cardiorythmine) is a sodium channel blocking, class 1A anti-arrhythmic agent. Ajmaline blocks HERG currents with an IC₅₀ of 1 μM in HEK cells and 42.3 μM in Xenopus oocytes. Ajmaline can be used for the research of the ventricular tachyarrhythmia .

HY-B1302

Quinidine hydrochloride monohydrate 15+ Cited Publications	Cardiovascular Disease Structural Classification Natural Products Classification of Application Fields Source classification Rubiaceae Cinchona calisaya Wedd. Plants Disease Research Fields	Potassium Channel Parasite
Quinidine hydrochloride monohydrate is an anti-arrythmic agent which is also a potent blocker of K ⁺ channel with an IC₅₀ of 19.9 μM.

HY-108451

Ononetin	Structural Classification Leguminosae Source classification Phenols Polyphenols Plants Ononis arvensis Linn.	TRP Channel
Ononetin, a natural deoxybenzoin, is a potent and selective TRPM3 channel blocker with an IC₅₀ of 0.3 μM .

HY-101245

Pilsicainide hydrochloride SUN-1165; Pilzicainide(hydrochloride)	Pyrrolizidine Alkaloids Structural Classification Alkaloids	Sodium Channel
Pilsicainide hydrochloride (SUN-1165) is an orally active sodium channel blocker and potent class Ic antiarrhythmic agent .

HY-B0628

Vinflunine	Structural Classification Natural Products Classification of Application Fields Source classification Plants Disease Research Fields Cancer	Microtubule/Tubulin
Vinflunine is a type of fluorinated vinca alkaloid that has the ability to block mitosis and interact with tubulin .

HY-P0173A

Chlorotoxin	Structural Classification Natural Products Animals Classification of Application Fields Source classification Disease Research Fields Cancer	Chloride Channel
Chlorotoxin is a 36 amino-acid peptide from the venom of the Israeli scorpion Leiurus quinquestriatus with anticancer activity. Chlorotoxin is a chloride channel blocker.

HY-Y0084

3,4,5-Trimethoxybenzoic acid Eudesmic acid; Trimethylgallic Acid	Structural Classification Paeonia lactiflora Pall. Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Plants Paeoniaceae Disease Research Fields	Others
3,4,5-Trimethoxybenzoic acid (Eudesmic acid;Trimethylgallic Acid) is a benzoic acid derivative. A building block in medicine and organic synthesis.

HY-N3990

Hardwickiic acid 1 Publications Verification (-)-Hardwikiic acid	Classification of Application Fields Neurological Disease Pueraria tuberosa (Roxb. ex Willd.) DC. Source classification Plants Compositae Infection other families Terpenoids Croton tiglium Linn. Diterpenoids Euphorbiaceae Disease Research Fields	Sodium Channel
Hardwickiic acid ((-)-Hardwikiic acid) is an antinociceptive compound that blocks Tetrodotoxin-sensitive voltage-dependent sodium channels. Hardwickiic acid shows insecticidal activity .

HY-P0173B

Chlorotoxin TFA 1 Publications Verification	Structural Classification Natural Products Classification of Application Fields Animals Source classification Disease Research Fields Cancer	Chloride Channel
Chlorotoxin TFA is a peptide isolated from the venom of the scorpion Leiurus quinquestriatus, acts as a chloride channel blocker . Anti-cancer activity .

HY-14589R

Chrysin (Standard)	Structural Classification Human Gut Microbiota Metabolites Flavonoids Flavones Source classification Phenols Polyphenols Bignoniaceae Plants Oroxylum indicum (Linn.) Bentham ex Kurz Endogenous metabolite	Estrogen Receptor/ERR
Chrysin (Standard) is the analytical standard of Chrysin. This product is intended for research and analytical applications. Chrysin is one of the most well known estrogen blockers.

HY-W040471

3′,5′-Dimethoxyacetophenone	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Scrophularia buergeriana Miq. Other Diseases Scrophulariaceae Plants Disease Research Fields	Others
3′,5′-Dimethoxyacetophenone is a natural ketone compound with antioxidant activities. 3′,5′-Dimethoxyacetophenone is a building block in the chemical synthesis .

HY-N0219R

Bicuculline (Standard)	Alkaloids Structural Classification Source classification Lamprocapnos spectabilis (L.) Fukuhara Plants Isoquinoline Alkaloids Papaveraceae	GABA Receptor
Bicuculline (Standard) is the analytical standard of Bicuculline. This product is intended for research and analytical applications. Bicuculline ((+)-Bicuculline) is A competing neurotransmitter GABAA receptor antagonist (IC₅₀=2 μM). Bicuculline also blocks Ca2+ activating potassium (SK) channels and subsequently blocks slow post-hyperpolarization (slow AHP). Bicuculline has anticonvulsant activity. Bicuculline can be used to induce seizures in mice .

HY-15122

Sinomenine 10+ Cited Publications	Structural Classification Neurological Disease Classification of Application Fields Sinomenium acutum(Thunb．)Rehd．Et Wils． Source classification Plants Menispermaceae Alkaloids Piperidine Alkaloids Monophenols Phenols Inflammation/Immunology Disease Research Fields	NF-κB Opioid Receptor Autophagy Apoptosis
Sinomenine, an alkaloid extracted from Sinomenium acutum, is a blocker of the NF-κB activation . Sinomenine also is an activator of μ-opioid receptor .

HY-N0663

Talatisamine	Alkaloids Pyrrole Alkaloids Source classification Ranunculaceae Aconitum carmichaeli Debx. Plants	Potassium Channel
Talatisamine, a aconitum alkaloid, is specific K ⁺ channel blocker. Talatisamine attenuates beta-amyloid oligomers induced neurotoxicity in cultured cortical neurons .

HY-B2136R

Tannic acid (Standard)	Structural Classification Liliaceae Ketones, Aldehydes, Acids Source classification Phenols Polyphenols Polygonatum odoratum (Mill.) Druce Plants	Potassium Channel
Tannic acid (Standard) is the analytical standard of Tannic acid. This product is intended for research and analytical applications. Tannic acid is a novel hERG channel blocker with IC50 of 3.4 μM.

HY-B0157A

Ketotifen fumarate 3 Publications Verification HC 20511 fumarate	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Histamine Receptor Endogenous Metabolite SARS-CoV Influenza Virus
Ketotifen (HC 20-511) fumarate is an orally active second-generation noncompetitive histamine 1 (H1) receptor blocker and mast cell stabilizer. Ketotifen fumarate can block 6-phosphogluconate dehydrogenase (PGD) in vitro. Ketotifen fumarate also has antiviral activity against SARS-CoV-2 and Influenza virus. Ketotifen fumarate can be used to the research of autoimmune encephalomyelitis (EAE) and asthma attack prevention .

HY-B0157

Ketotifen 3 Publications Verification HC 20-511	Infection Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields Endocrinology	Endogenous Metabolite Histamine Receptor SARS-CoV Influenza Virus
Ketotifen (HC 20-511) is an orally active second-generation noncompetitive histamine 1 (H1) receptor blocker and mast cell stabilizer. Ketotifen can block 6-phosphogluconate dehydrogenase (PGD) in vitro. Ketotifen also has antiviral activity against SARS-CoV-2 and Influenza virus. Ketotifen can be used to the research of autoimmune encephalomyelitis (EAE) and asthma attack prevention .

HY-N2149

Tomatidine 5 Publications Verification	Cardiovascular Disease Structural Classification Classification of Application Fields Anti-aging Source classification Pyridine Alkaloids Solanum lycopersicum L. Plants Alkaloids Solanaceae Inflammation/Immunology Disease Research Fields Steroids	NF-κB JNK Autophagy Endogenous Metabolite
Tomatidine acts as an anti-inflammatory agent by blocking NF-κB and JNK signaling . Tomatidine activates autophagy either in mammal cells or C elegans .

HY-15122A

Sinomenine hydrochloride 10+ Cited Publications Cucoline hydrochloride	Structural Classification Neurological Disease Classification of Application Fields Sinomenium acutum(Thunb．)Rehd．Et Wils． Source classification Plants Menispermaceae Alkaloids Piperidine Alkaloids Monophenols Phenols Inflammation/Immunology Disease Research Fields	NF-κB Opioid Receptor Autophagy Apoptosis
Sinomenine hydrochloride (Cucoline hydrochloride), an alkaloid extracted from Sinomenium acutum, is a blocker of the NF-κB activation . Sinomenine also is an activator of μ-opioid receptor .

HY-126050

(R)-Pantetheine Pantetheine	Structural Classification Natural Products Human Gut Microbiota Metabolites Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
(R)-Pantetheine is the biosynthetic precursor to CoA. (R)-Pantetheine and its corresponding disulfide pantethine, play a key role in metabolism as a building block of coenzyme A (CoA) .

HY-N0714

Berbamine 5+ Cited Publications	Alkaloids Structural Classification Phellodendron amurense Rupr. Monophenols Classification of Application Fields Source classification Rutaceae Phenols Plants Isoquinoline Alkaloids Disease Research Fields Cancer	NF-κB Autophagy
Berbamine is a natural compound extracted from traditional Chinese medicine Phellodendron amurense Rupr. with anti-tumor, immunomodulatory and cardiovascular effects. Berbamine is a calcium channel blocker.

Cat. No.	Product Name	Chemical Structure

HY-12515AS

Nicardipine-d3 hydrochloride
Nicardipine-d₃ (hydrochloride) (YC-93 D3) is the deuterium labeled Nicardipine hydrochloride. Nicardipine hydrochloride is a calcium channel blocker with an IC50 of 1 μM for blocking cardiac calcium channels. Nicardipine hydrochloride acts as an agent for chronic stable angina and for controlling blood pressure[1].

HY-125818S3

Cytidine-5'-triphosphate-13C9 dilithium

Cytidine-5'-triphosphate- ¹³C₉ (Cytidine triphosphate- ¹³C₉ dilithium; 5'-CTP- ¹³C₉) dilithium is ¹³C-labeled Cytidine-5'-triphosphate (HY-125818). Cytidine 5′-triphosphate (Cytidine triphosphate; 5'-CTP) is a nucleoside triphosphate and serves as a building block for nucleotides and nucleic acids, lipid biosynthesis. Cytidine triphosphate synthase can catalyze the formation of cytidine 5′-triphosphate from uridine 5′-triphosphate (UTP). Cytidine 5′-triphosphate is an essential biomolecule?in the de novo?pyrimidine biosynthetic pathway in?T. gondii.

HY-125818S6

Cytidine-5'-triphosphate-15N3 dilithium

Cytidine-5'-triphosphate- ¹⁵N₃ (Cytidine triphosphate- ¹⁵N₃ dilithium; 5'-CTP- ¹⁵N₃) dilithium is ¹⁵N labeled Cytidine-5'-triphosphate (HY-125818). Cytidine 5′-triphosphate (Cytidine triphosphate; 5'-CTP) is a nucleoside triphosphate and serves as a building block for nucleotides and nucleic acids, lipid biosynthesis. Cytidine triphosphate synthase can catalyze the formation of cytidine 5′-triphosphate from uridine 5′-triphosphate (UTP). Cytidine 5′-triphosphate is an essential biomolecule?in the de novo?pyrimidine biosynthetic pathway in?T. gondii.

HY-12515AS2

Nicardipine-d4 hydrochloride
Nicardipine-d₄ hydrochloride is deuterated labeled Nicardipine hydrochloride (HY-12515A). Nicardipine hydrochloride (YC-93) is a calcium channel blocker with an IC₅₀ of 1 μM for blocking cardiac calcium channels. Nicardipine hydrochloride acts as an agent for chronic stable angina and for controlling blood pressure .

HY-125818S4

Cytidine-5'-triphosphate-d14 dilithium

Cytidine-5'-triphosphate-d₁₄ (Cytidine triphosphate-d₁₄ dilithium; 5'-CTP-d₁₄) dilithium is deuterium labeled Cytidine-5'-triphosphate (HY-125818). Cytidine 5′-triphosphate (Cytidine triphosphate; 5'-CTP) is a nucleoside triphosphate and serves as a building block for nucleotides and nucleic acids, lipid biosynthesis. Cytidine triphosphate synthase can catalyze the formation of cytidine 5′-triphosphate from uridine 5′-triphosphate (UTP). Cytidine 5′-triphosphate is an essential biomolecule?in the de novo?pyrimidine biosynthetic pathway in?T. gondii.

HY-B1392S

Esmolol-d7 hydrochloride
Esmolol-d₇ (hydrochloride) is the deuterium labeled Esmolol hydrochloride. Esmolol hydrochloride is a beta adrenergic receptor blocker[1][2].

HY-101621S

Teludipine-d6
Teludipine-d₆ is the deuterium labeled Teludipine hydrochloride. Teludipine is a lipophilic calcium channel blocker[1][2].

HY-125818S2

Cytidine-5'-triphosphate-13C,d1 dilithium

Cytidine-5'-triphosphate- ¹³C,d₁ (Cytidine triphosphate- ¹³C,d₁ dilithium; 5'-CTP- ¹³C,d₁) dilithium is deuterium and ¹³C-labeled Cytidine-5'-triphosphate (HY-125818). Cytidine 5′-triphosphate (Cytidine triphosphate; 5'-CTP) is a nucleoside triphosphate and serves as a building block for nucleotides and nucleic acids, lipid biosynthesis. Cytidine triphosphate synthase can catalyze the formation of cytidine 5′-triphosphate from uridine 5′-triphosphate (UTP). Cytidine 5′-triphosphate is an essential biomolecule?in the de novo?pyrimidine biosynthetic pathway in?T. gondii.

HY-116448S

Metaflumizone-d4
Metaflumizone-d₄ is deuterium labeled Metaflumizone. Metaflumizone is a semicarbazone insecticide, acts as a potent sodium channel blocker[1].

HY-125818S5

Cytidine-5'-triphosphate-15N3,d14 dilithium

Cytidine-5'-triphosphate- ¹⁵N₃,d₁₄ (Cytidine triphosphate- ¹⁵N₃,d₁₄ dilithium; 5'-CTP- ¹⁵N₃,d₁₄) dilithium is deuterium and ¹⁵N labeled Cytidine-5'-triphosphate (HY-125818). Cytidine 5′-triphosphate (Cytidine triphosphate; 5'-CTP) is a nucleoside triphosphate and serves as a building block for nucleotides and nucleic acids, lipid biosynthesis. Cytidine triphosphate synthase can catalyze the formation of cytidine 5′-triphosphate from uridine 5′-triphosphate (UTP). Cytidine 5′-triphosphate is an essential biomolecule?in the de novo?pyrimidine biosynthetic pathway in?T. gondii.

HY-B0804S

Nadolol-d9
Nadolol-d₉ is the deuterium labeled Nadolol. Nadolol is a non-selective and orally active β-adrenergic receptors blocker[1].

HY-B0612DS

(R)-Lercanidipine-d3 hydrochloride
(R)-lercanidipine D3 (hydrochloride) is a deuterium labeled (R)-Lercanidipine hydrochloride. (R)-Lercanidipine-d₃ (hydrochloride), the R-enantiomer of Lercanidipine, is a calcium channel blocker[1].

HY-B0202S3

Irbesartan-d7
Irbesartan-d₇ is deuterated labeled Irbesartan (HY-B0202). Irbesartan (SR-47436) is an orally active *Ang II type 1 (AT1) receptor blocker* (ARB)**. Irbesartan can relax the blood vessels, low blood pressure and increase the supply of blood and oxygen to the heart. Irbesartan can be used for the research of high blood pressure, heart failure, and diabetic kidney disease .

HY-B0202AS

Irbesartan-d7 hydrochloride

Irbesartan-d₇ hydrochloride is deuterated labeled Irbesartan hydrochloride (HY-B0202A). Irbesartan (SR-47436) hydrochloride is an orally active Ang II type 1 (AT1) receptor blocker (ARB). Irbesartan hydrochloride can relax the blood vessels, low blood pressure and increase the supply of blood and oxygen to the heart. Irbesartan hydrochloride can be used for the research of high blood pressure, heart failure, and diabetic kidney disease .

HY-A0093S

Mexiletine-d6 hydrochloride
Mexiletine-d₆ (hydrochloride) is a deuterium labeled Mexiletine hydrochloride (KOE-1173 hydrochloride). Mexiletine hydrochloride, a Class IB antianhythmic, is a non-selective voltage-gated sodium channel blocker[1].

HY-A0093S1

Mexiletine-d3 hydrochloride
Mexiletine-d₃ (hydrochloride) is deuterium labeled Mexiletine (hydrochloride). Mexiletine hydrochloride (KOE-1173 hydrochloride), a Class IB antianhythmic, is a non-selective voltage-gated sodium channel blocker[1][2].

HY-W778207

2'-Deoxyadenosine-13C5 monohydrate
2'-Deoxyadenosine- ¹³C5 (monohydrate) is the ¹³C labeled isotope of 2'-Deoxyadenosine- ¹³C5 (monohydrate).2'-Deoxyadenosine monohydrate is a deoxyribonucleoside, a building block in chemical synthesis.2'-Deoxyadenosine monohydrate is a deoxyribonucleoside. A building block in the chemical synthesis.

HY-B0405S

Bupivacaine-d9
Bupivacaine-d₉9 is a deuterium labeled Bupivacaine. Bupivacaine is a NMDA receptor inhibitor.Bupivacaine can block sodium, L-calcium, and potassium channels.Bupivacaine potently blocks SCN5A channels with the IC50 of 69.5 μM. Bupivacaine can be used for the research of chronic pain[1][2][3].

HY-B0284S

Nifedipine-d6 1 Publications Verification
Nifedipine-d₆ is deuterium labeled nifedipine, and nifedipine is a potent calcium channel blocker.

HY-B0246S1

Carbamazepine-d2
Carbamazepine-d₂ is the deuterium labeled Carbamazepine. Carbamazepine, a sodium channel blocker, is an anticonvulsant agent.

HY-B1090S

Cinnarizine-d8
Cinnarizine-d₈ is a deuterium labeled Cinnarizine. Cinnarizine is an antihistamine and a calcium channel blocker.

HY-B0437AS

Sotalol-d6 hydrochloride
Sotalol-d₆ (hydrochloride) is a deuterium labeled Sotalol hydrochloride. Sotalol hydrochloride is an orally active, non-selective competitive β-adrenergic receptor blocker. Sotalol hydrochloride is a potent antiarrhythmic agent that can be used for the research of pediatric arrhythmias. Sotalol hydrochloride blocks β-receptors, and potassium KCNH2 channels[1][2].

HY-B0114S1

Oxcarbazepine-d4-1
Oxcarbazepine-d₄-1 is deuterium labeled Oxcarbazepine. Oxcarbazepine is a sodium channel blocker[1]. Oxcarbazepine significantly inhibits glioblastoma cell growth and induces apoptosis or G2/M arrest in glioblastoma cell lines[2]. Anti-cancer and anticonvulsant effects[2][3].

HY-B0023S

Azelnidipine-d7
Azelnidipine-d₇ is deuterium labeled Azelnidipine, which is a L-type calcium channel blocker.

HY-B0193AS

Prazosin-d8 hydrochloride
Prazosin-d8 hydrochloride is the deuterium labeled Prazosin hydrochloride. Prazosin hydrochloride is an alpha-adrenergic blocker .

HY-N0221S

Daurisoline-d2
Daurisoline-d₂ is the deuterium labeled Daurisoline (HY-N0221). Daurisoline is a bis-benzylisoquinoline alkaloid that can be isolated from Menispermum dauricum and Rhizoma Menispermi. Daurisoline exerts a blocking effect on hERG and has antiarrhythmic effects. Daurisoline is a potent autophagy blocker that can be used for the research of cancer .

HY-N0221S1

Daurisoline-d5
Daurisoline-d₅ is the deuterium labeled Daurisoline (HY-N0221). Daurisoline is a bis-benzylisoquinoline alkaloid that can be isolated from Menispermum dauricum and Rhizoma Menispermi. Daurisoline exerts a blocking effect on hERG and has antiarrhythmic effects. Daurisoline is a potent autophagy blocker that can be used for the research of cancer .

HY-N0221S2

Daurisoline-d11
Daurisoline-d₁₁ is the deuterium labeled Daurisoline (HY-N0221). Daurisoline is a bis-benzylisoquinoline alkaloid that can be isolated from Menispermum dauricum and Rhizoma Menispermi. Daurisoline exerts a blocking effect on hERG and has antiarrhythmic effects. Daurisoline is a potent autophagy blocker that can be used for the research of cancer .

HY-B0437S

Sotalol-d6
Sotalol-d₆ is the deuterium labeled Sotalol. Sotalol is an orally active, non-selective β-adrenergic receptor blocker. Sotalol is a potent antiarrhythmic agent that can be used for the research of pediatric arrhythmias. Sotalol blocks β-receptors, and potassium KCNH2 channels. Antiepileptic Agent[1][2][3][4].

HY-B0317AS

Amlodipine-d4 maleate
Amlodipine-d₄ (maleate) is the deuterium labeled Amlodipine maleate. Amlodipine maleate is a dihydropyridine calcium channel blocker, acts as an orally active antianginal agent. Amlodipine maleate blocks the voltage-dependent L-type calcium channels, thereby inhibiting the initial influx of calcium. Amlodipine maleate can be used for the research of high blood pressure and cancer[1][2][3].

HY-B0114S

Oxcarbazepine-D4
Oxcarbazepine-d₄ (GP 47680-D4) is the deuterium labeled Oxcarbazepine. Oxcarbazepine is a sodium channel blocker[1]. Oxcarbazepine significantly inhibits glioblastoma cell growth and induces apoptosis or G2/M arrest in glioblastoma cell lines[2]. Anti-cancer and anticonvulsant effects[2][3].

HY-117275S

Meclofenamic acid-d4
Meclofenamic acid-d₄ is the deuterium labeled Meclofenamic acid. Meclofenamic Acid (Meclofenamate), a non-steroidal, anti-inflammatory agent, is a highly selective fat mass and obesity-associated (FTO) enzyme inhibitor. Meclofenamic Acid competes with FTO binding for the m(6)A-containing nucleic acid. Meclofenamic acid is a non-selective gap-junction blocker[1][2][3].

HY-108974S

Drotaverine-d10 hydrochloride

Drotaverine-d₁₀ (hydrochloride) is the deuterium labeled Drotaverine hydrochloride. Drotaverine hydrochloride is a type 4 cyclic nucleotide phosphodiesterase (PDE4) inhibitor and an L-type voltage-dependent calcium channel (L-VDCC) blocker, blocks the degradation of 3',5'-cyclic adenosine monophosphate. Drotaverine hydrochloride exhibits in vivo antispasmodic efficacy without anticholinergic effects[1][2].

HY-B0317S1

Amlodipine-d4
Amlodipine-d₄ is a deuterium labeled Amlodipine (HY-B0317). Amlodipine, an antianginal agent and an orally active dihydropyridine calcium channel blocker, works by blocking the voltage-dependent L-type calcium channels, thereby inhibiting the initial influx of calcium. Amlodipine can be used for the research of high blood pressure and cancer .

HY-B0317AS1

Amlodipine-d9 maleate

Amlodipine-d₉ maleate is deuterated labeled Amlodipine maleate (HY-B0317A). Amlodipine maleate is a dihydropyridine calcium channel blocker, acts as an orally active antianginal agent. Amlodipine maleate blocks the voltage-dependent L-type calcium channels, thereby inhibiting the initial influx of calcium. Amlodipine maleate can be used for the research of high blood pressure and cancer .

HY-B0401S

Tolbutamide-d9
Tolbutamide-d₉ is the deuterium labeled Tolbutamide. Tolbutamide is a first generation potassium channel blocker, sulfonylurea oral hypoglycemic agent.

HY-B0317S

Amlodipine-1,1,2,2-d4 maleate
Amlodipine-1,1,2,2-d₄ (maleate) is the deuterium labeled Amlodipine. Amlodipine, an antianginal agent and an orally active dihydropyridine calcium channel blocker, works by blocking the voltage-dependent L-type calcium channels, thereby inhibiting the initial influx of calcium. Amlodipine can be used for the research of high blood pressure and cancer[1][2][3].

HY-B0317BS

Amlodipine-d4 besylate

Amlodipine-d₄ (besylate) is the deuterium labeled Amlodipine besylate. Amlodipine besylate (Amlodipine benzenesulfonate), an antianginal agent and an orally active dihydropyridine calcium channel blocker, works by blocking the voltage-dependent L-type calcium channels, thereby inhibiting the initial influx of calcium. Amlodipine besylate can be used for the research of high blood pressure and cancer[1][2][3].

HY-B0401S1

Tolbutamide-13C
Tolbutamide- ¹³C is the ¹³C-labeled Tolbutamide. Tolbutamide is a first generation potassium channel blocker, sulfonylurea oral hypoglycemic agent.

HY-B0419S

Manidipine-d4
Manidipine-d₄ is the deuterium labeled Manidipine. Manidipine is a calcium channel blocker that is used clinically as an antihypertensive[1][2].

HY-12751S

Trimethobenzamide-d6
Trimethobenzamide-d₆ is deuterium labeled Trimethobenzamide. Trimethobenzamide is a blocker of the D2 receptor. Trimethobenzamide is an antiemetic used to prevent nausea and vomiting.

HY-B0076S

Bisoprolol-d7 hemifumarate
Bisoprolol-d₇ (hemifumarate) is the deuterium labeled Bisoprolol hemifumarate. Bisoprolol hemifumarate is a selective type β1 adrenergic receptor blocker.

HY-B0284S1

Nifedipine-d4
Nifedipine-d₄ is the deuterium labeled Nifedipine. Nifedipine (BAY-a-1040) is a potent calcium channel blocker and agent of choice for cardiac insufficiencies.

HY-B0809S

Theophylline-d6
Theophylline-d₆ is the deuterium labeled Theophylline. Theophylline is a nonselective phosphodiesterase (PDE) inhibitor, adenosine receptor blocker, and histone deacetylase (HDAC) activator.

HY-13204S

Biperiden-d5 hydrochloride
Biperiden-d₅ (hydrochloride) is the deuterium labeled Biperiden hydrochloride. Biperiden (KL 373) hydrochloride is an antiparkinsonian agent, which is the selective central M1 cholinoreceptors blocker.

HY-B0312S1

Dipyridamole-d16
Dipyridamole-d₁₆ is the deuterium labeled Dipyridamole. Dipyridamole (Persantine) is a phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells.

HY-B1319S1

Pramocaine-d9 hydrochloride
Pramocaine-d₉ (hydrochloride) is deuterium labeled Pramocaine (hydrochloride). Pramocaine hydrochloride decreases the permeability of neuronal membranes to sodium ions, blocking both initiation and conduction of nerve impulses.

HY-B0006S

Carvedilol-d3
Carvedilol-d₃ is the deuterium labeled Carvedilol. Carvedilol (BM 14190) is a non-selective β/α-1 blocker[1]. Carvedilol inhibits lipid peroxidation in a dose-dependent manner with an IC50 of 5 μM. Carvedilol is a multiple action antihypertensive agent with potential use in angina and congestive heart failure[2]. Carvedilol is an autophagy inducer that inhibits the NLRP3 inflammasome[3].

HY-B0006S1

Carvedilol-d4
Carvedilol-d₄ is the deuterium labeled Carvedilol. Carvedilol (BM 14190) is a non-selective β/α-1 blocker[1]. Carvedilol inhibits lipid peroxidation in a dose-dependent manner with an IC50 of 5 μM. Carvedilol is a multiple action antihypertensive agent with potential use in angina and congestive heart failure[2]. Carvedilol is an autophagy inducer that inhibits the NLRP3 inflammasome[3].

HY-B0006S2

Carvedilol-d5
Carvedilol-d₅ is deuterium labeled Carvedilol. Carvedilol (BM 14190) is a non-selective β/α-1 blocker[1]. Carvedilol inhibits lipid peroxidation in a dose-dependent manner with an IC50 of 5 μM. Carvedilol is a multiple action antihypertensive agent with potential use in angina and congestive heart failure[2]. Carvedilol is an autophagy inducer that inhibits the NLRP3 inflammasome[3].

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