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6-Aminohexanoic acid-d<sub>6</sub>

" in MedChemExpress (MCE) Product Catalog:

4142

Inhibitors & Agonists

11

Biochemical Assay Reagents

43

Peptides

1

Inhibitory Antibodies

14

Natural
Products

11

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4024

Isotope-Labeled Compounds

4

Antibodies

17

Click Chemistry

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B0236S

    EACA-d<sub>6sub>; Epsilon-Amino-n-caproic acid-d<sub>6sub>; 6-Aminohexanoic acid-d<sub>6sub>

    Isotope-Labeled Compounds Metabolic Disease
    6-Aminocaproic acid-d6 is deuterium labeled 6-Aminocaproic acid. 6-Aminocaproic acid (EACA), a monoamino carboxylic acid, is a potent and orally active inhibitor of plasmin and plasminogen. 6-Aminocaproic acid is a potent antifibrinolytic agent. 6-Aminocaproic acid prevents clot lysis through the competitive binding of lysine residues on plasminogen, inhibiting plasmin formation and reducing fibrinolysis. 6-Aminocaproic acid can be used for the research of bleeding disorders[1][2].
    6-Aminocaproic acid-d6
  • HY-101218

    N-(+)-Biotinyl-6-Aminohexanoic acid

    Sialyltransferase Others
    N-Biotinyl-6-aminohexanoic acid (N-(+)-Biotinyl-6-aminohexanoic acid) can be used to perform biotinylation .
    N-Biotinyl-6-aminohexanoic acid
  • HY-W007529

    PROTAC Linkers Cancer
    Boc-6-aminohexanoic acid is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
    Boc-6-aminohexanoic acid
  • HY-B0236
    6-Aminocaproic acid
    2 Publications Verification

    EACA; Epsilon-Amino-n-caproic acid; 6-Aminohexanoic acid

    PAI-1 Metabolic Disease Cancer
    6-Aminocaproic acid (EACA), a monoamino carboxylic acid, is a potent and orally active inhibitor of plasmin and plasminogen. 6-Aminocaproic acid is a potent antifibrinolytic agent. 6-Aminocaproic acid prevents clot lysis through the competitive binding of lysine residues on plasminogen, inhibiting plasmin formation and reducing fibrinolysis. 6-Aminocaproic acid can be used for the research of bleeding disorders .
    6-Aminocaproic acid
  • HY-B0236S1

    EACA-d<sub>10sub>; Epsilon-Amino-n-caproic acid-d<sub>10sub>; 6-Aminohexanoic acid-d<sub>10sub>

    Isotope-Labeled Compounds Metabolic Disease
    6-Aminocaproic acid-d10 is the deuterium labeled 6-Aminocaproic acid. 6-Aminocaproic acid (EACA), a monoamino carboxylic acid, is a potent and orally active inhibitor of plasmin and plasminogen. 6-Aminocaproic acid is a potent antifibrinolytic agent. 6-Aminocaproic acid prevents clot lysis through the competitive binding of lysine residues on plasminogen, inhibiting plasmin formation and reducing fibrinolysis. 6-Aminocaproic acid can be used for the research of bleeding disorders[1][2].
    6-Aminocaproic acid-d10
  • HY-B0236A

    EACA hydrochloride; Epsilon-Amino-n-caproic acid hydrochloride; 6-Aminohexanoic acid hydrochloride

    Drug Derivative PAI-1 Metabolic Disease Cancer
    6-Aminocaproic acid hydrochloride, a monoamino carboxylic acid, is a potent and orally active inhibitor of plasmin and plasminogen. 6-Aminocaproic acid is a potent antifibrinolytic agent. 6-Aminocaproic acid prevents clot lysis through the competitive binding of lysine residues on plasminogen, inhibiting plasmin formation and reducing fibrinolysis. 6-Aminocaproic acid can be used for the research of bleeding disorders .
    6-Aminocaproic acid hydrochloride
  • HY-146227

    Topoisomerase Apoptosis Cancer
    DNA topoisomerase II inhibitor 1 (compound 8ed) is a potent DNA topoisomerase II inhibitor. DNA topoisomerase II inhibitor 1 shows anti-proliferative activity. DNA topoisomerase II inhibitor 1 induces apoptosis and cell cycle arrest at sub G1 phase .
    DNA topoisomerase II inhibitor 1
  • HY-RS13999

    Small Interfering RNA (siRNA) Others

    SUB1 Human Pre-designed siRNA Set A contains three designed siRNAs for SUB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    SUB1 Human Pre-designed siRNA Set A
    SUB1 Human Pre-designed siRNA Set A
  • HY-B1804S1

    Trioctanoin-d<sub>50sub>; Glyceryl trioctanoate-d<sub>50sub>

    Isotope-Labeled Compounds Endogenous Metabolite Neurological Disease Inflammation/Immunology
    Tricaprilin-d50 (Trioctanoin-d50 is the deuterium labeled Tricaprilin (HY-B1804). Tricaprilin is an orally active and well tolerated ketogenic agent that safely induces ketosis. Tricaprilin restores brain electrical activity and metabolism to help counteract neuroinflammation in migraine. Tricaprilin is promising for research of migraine prevention and Alzheimer’s disease (AD). Tricaprilin is a pure C8 medium chain triglyceride (MCT) .
    Tricaprilin-d50
  • HY-B1804S2

    Trioctanoin-d<sub>15sub>; Glyceryl trioctanoate-d<sub>15sub>

    Isotope-Labeled Compounds Endogenous Metabolite Neurological Disease Inflammation/Immunology
    Tricaprilin-d15 (Trioctanoin-d15 is the deuterium labeled Tricaprilin (HY-B1804). Tricaprilin is an orally active and well tolerated ketogenic agent that safely induces ketosis. Tricaprilin restores brain electrical activity and metabolism to help counteract neuroinflammation in migraine. Tricaprilin is promising for research of migraine prevention and Alzheimer’s disease (AD). Tricaprilin is a pure C8 medium chain triglyceride (MCT) .
    Tricaprilin-d15
  • HY-P5057B

    Fluorescent Dye Bacterial Infection
    5-FAM-Ahx-LL-37 TFA is a 5-FAM (HY-66022) labeled LL-37, human (HY-P1222). The carboxyfluorescein group is attached via a 6-carbon spacer, 6-Aminohexanoic acid (Ahx, HY-B0236). LL-37, human is a 37-residue, amphipathic, cathelicidin-derived antimicrobial peptide, which exhibits a broad spectrum of antimicrobial activity .
    5-FAM-Ahx-LL-37 TFA
  • HY-B0236R

    EACA(Standard); Epsilon-Amino-n-caproic acid(Standard); 6-Aminohexanoic acid (Standard)

    PAI-1 Others Metabolic Disease Cancer
    6-Aminocaproic acid (Standard) is the analytical standard of 6-Aminocaproic acid. This product is intended for research and analytical applications. 6-Aminocaproic acid (EACA), a monoamino carboxylic acid, is a potent and orally active inhibitor of plasmin and plasminogen. 6-Aminocaproic acid is a potent antifibrinolytic agent. 6-Aminocaproic acid prevents clot lysis through the competitive binding of lysine residues on plasminogen, inhibiting plasmin formation and reducing fibrinolysis. 6-Aminocaproic acid can be used for the research of bleeding disorders .
    6-Aminocaproic acid (Standard)
  • HY-100560S

    (S)​-​(+)​-​Abscisic acid-d<sub>6sub>; ABA-d<sub>6sub>

    Proton Pump Isotope-Labeled Compounds Metabolic Disease
    Abscisic acid-d6 is deuterium labeled Abscisic acid. Abscisic acid inhibits proton pump (H +-ATPase) .
    Abscisic acid-d6
  • HY-N0593S2

    Cholanoic acid-d<sub>6sub>; Desoxycholic acid-d<sub>6sub>

    Isotope-Labeled Compounds G protein-coupled Bile Acid Receptor 1 Endogenous Metabolite Metabolic Disease
    Deoxycholic acid-d6 is the deuterium labeled Deoxycholic acid. Deoxycholic acid is specifically responsible for activating the G protein-coupled bile acid receptor TGR5 that stimulates brown adipose tissue (BAT) thermogenic activity.
    Deoxycholic acid-d6
  • HY-B1350S

    Fusidate-d<sub>6sub>; SQ-16603-d<sub>6sub>

    Bacterial Antibiotic Infection
    Fusidic acid-d6 is the deuterium labeled Fusidic acid. Fusidic acid (Fusidate) a bacteriostatic antibiotic produced from the Fusidium coccineum fungus, belongs to the class of steroids. Fusidic acid has no corticosteroid effects. Fusidic acid inhibits the growth of bacteria by preventing the release of translation elongation factor G (EF-G) from the ribosome[1][2].
    Fusidic acid-d6
  • HY-N0610AS

    3-Phenylacrylic acid-d<sub>6sub>; β-Phenylacrylic acid-d<sub>6sub>

    Endogenous Metabolite Cancer
    Cinnamic acid-d6 is the deuterium labeled Cinnamic acid. Cinnamic acid has potential use in cancer intervention, with IC50s of 1-4.5 mM in glioblastoma, melanoma, prostate and lung carcinoma cells.
    Cinnamic acid-d6
  • HY-12222S

    INT-747-d<sub>5sub>; 6-ECDCA-d<sub>5sub>; 6-Ethylchenodeoxycholic acid-d<sub>5sub>

    FXR Autophagy Others
    Obeticholic acid-d5 is the deuterium labeled Obeticholic acid. Obeticholic acid (INT-747) is a potent, selective and orally active FXR agonist with an EC50 of 99 nM. Obeticholic acid has anticholeretic and anti-inflammation effect. Obeticholic acid also induces autophagy[1][2][3].
    Obeticholic acid-d5
  • HY-131503S

    13-MTD-d<sub>6sub>; 13-Methylmyristic acid-d<sub>6sub>

    Isotope-Labeled Compounds Apoptosis Cancer
    13-Methyltetradecanoic acid-d6 is a deuterated labeled 13-Methyltetradecanoic acid . 13-Methyltetradecanoic acid (13-MTD), a saturated branched-chain fatty acid with potent anticancer effects. 13-Methyltetradecanoic acid induces apoptosis in many types of human cancer cells .
    13-Methyltetradecanoic acid-d6
  • HY-14649S3

    Vitamin A acid-d<sub>6sub>; all-trans-Retinoic acid-d<sub>6sub>; ATRA-d<sub>6sub>

    Isotope-Labeled Compounds RAR/RXR PPAR Autophagy Endogenous Metabolite Cancer
    Retinoic acid-d6 is the deuterium labeled Retinoic acid[1]. Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha[2][3][4][5][6][7].
    Retinoic acid-d6
  • HY-10844S1

    PA-824-d<sub>5sub>; (S)-PA 824-d<sub>5sub>

    Antibiotic Bacterial Isotope-Labeled Compounds Infection Cancer
    Pretomanid-d5 is deuterated labeled Pretomanid (HY-10844). Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 μg/mL.
    Pretomanid-d5
  • HY-10585S1

    VPA-d<sub>6sub>; 2-Propylpentanoic acid-d<sub>6sub>

    HDAC Autophagy Mitophagy HIV Notch Endogenous Metabolite Cancer
    Valproic acid-d6 is the deuterium labeled Valproic acid. Valproic acid (VPA; 2-Propylpentanoic Acid) is an HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid sodium salt is used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches[1][2].
    Valproic acid-d6
  • HY-P10215

    Parasite Infection
    Ac-{Cpg}-Thr-Ala-{Ala(CO)}-Asp-{Cpg}-NH2 (compound 40) is a potent Plasmodium subtilisin-like protease 1 (SUB1) inhibitor. SUB1-IN-1 shows IC50 values of 12 nM and 10 nM against P. vivax and P. falciparum SUB1 (Pv- and PfSUB1), respectively .
    Ac-{Cpg}-Thr-Ala-{Ala(CO)}-Asp-{Cpg}-NH2
  • HY-N0420S

    Wormwood acid-d<sub>6sub>

    Endogenous Metabolite Metabolic Disease
    Succinic acid-d6 is the deuterium labeled Succinic acid. Succinic acid is an intermediate product of the tricarboxylic acid cycle, as well as one of fermentation products of anaerobic metabolism.
    Succinic acid-d6
  • HY-101108S

    AGN 190299-d<sub>6sub>

    Isotope-Labeled Compounds Drug Metabolite Others
    Tazarotenic acid-d6 is deuterium labeled Tazarotenic acid. Tazarotenic acid is the metabolite of Tazarotene. Tazarotenic acid binding to retinoic acid receptors (RARs) is the probable molecular target of retinoid action. Tazarotenic acid has the potential for the research of warty dyskeratoma .
    Tazarotenic acid-d6
  • HY-B0167S

    2-Hydroxybenzoic acid-d<sub>6sub>

    Isotope-Labeled Compounds COX Autophagy Mitophagy Apoptosis Inflammation/Immunology Cancer
    Salicylic acid-d6 is a deuterium labeled Salicylic acid (HY-B0167). Salicylic acid inhibits cyclo-oxygenase-2 (COX-2) activity independently of transcription factor (NF-κB) activation .
    Salicylic acid-d6
  • HY-W018790S

    4-dimethylamino benzoic acid-d<sub>6sub>

    Isotope-Labeled Compounds Others
    4-Dimethylamino benzoic acid-d6 is deuterium labeled 4-Dimethylaminobenzoic acid.
    4-Dimethylamino benzoic acid-d6
  • HY-119695S

    Tenivastatin-d<sub>6sub>

    Isotope-Labeled Compounds HMG-CoA Reductase (HMGCR) Reactive Oxygen Species Cardiovascular Disease Cancer
    Simvastatin acid-d6 (Tenivastatin-d6) is deuterium labeled Simvastatin acid. Simvastatin acid (Tenivastatin), a hydrolysate of Simvastatin (HY-17502), is a HMG-CoA reductase (HMGCR) inhibitor. Simvastatin acid reduces Indoxyl sulfate-mediated reactive oxygen species (ROS) production in human cardiomyocytes. Simvastatin acid can also modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 gene .
    Simvastatin acid-d6
  • HY-70002BS

    MDV3100 carboxylic acid-d<sub>6sub>

    Autophagy Androgen Receptor Isotope-Labeled Compounds Cancer
    Enzalutamide carboxylic acid-d6 is the deuterium labeled Enzalutamide carboxylic acid (MDV3100 carboxylic acid). Enzalutamide carboxylic acid is an inactive metabolite of Enzalutamide[1].
    Enzalutamide carboxylic acid-d6
  • HY-A0143S

    DGLA-d<sub>6sub>; all-cis-8,11,14-Eicosatrienoic acid-d<sub>6sub>

    Endogenous Metabolite Cardiovascular Disease Inflammation/Immunology Cancer
    Dihomo-γ-linolenic acid-d6 (DGLA-d6) is the deuterium labeled Dihomo-γ-linolenic acid. Dihomo-γ-linolenic acid (all-cis-8,11,14-Eicosatrienoic acid) is a 20-carbon ω-6 fatty acid, with anti-inflammatory and anti-proliferative activities. Dihomo-γ-linolenic acid attenuates atherosclerosis in the apolipoprotein E deficient mouse model system[1][2][3].
    Dihomo-γ-linolenic acid-d6
  • HY-157938S

    6α-ethyl Cheodeoxycholic acid-d4, Obeticholic acid-d<sub>4sub>

    Isotope-Labeled Compounds Others
    6-ECDCA-d4 (6α-ethyl Cheodeoxycholic Acid-d4, Obeticholic Acid-d4) is deuterium labeled 6-ECDCA .
    6-ECDCA-d4
  • HY-12771S2

    Mebeverine metabolite O-desmethyl Mebeverine acid-d<sub>6sub>

    Isotope-Labeled Compounds Drug Metabolite Neurological Disease
    O-Desmethyl Mebeverine acid-d6 is deuterium labeled O-desmethyl Mebeverine acid.
    O-Desmethyl Mebeverine acid-d6
  • HY-108398AS

    5,8,11-Eicosatrienoic acid-d<sub>6sub>

    Isotope-Labeled Compounds Metabolic Disease Cancer
    Mead acid-d6 is the deuterium labeled Mead acid. Mead acid (5,8,11-Eicosatrienoic acid), an unsaturated (Omega-9) fatty acid, is an indicator of essential fatty acid deficiency[1].
    Mead acid-d6
  • HY-N0351S1

    trans-4-Hydroxycinnamic acid-d<sub>6sub>

    Endogenous Metabolite Cancer
    p-Coumaric acid-d6 is the deuterium labeled p-Coumaric acid (HY-N0351). p-Coumaric acid is the abundant isomer of cinnamic acid which has antitumor and anti-mutagenic activities[1][2].
    p-Coumaric acid-d6
  • HY-W056964S

    Naphthalene-2,6-dicarboxylate-d<sub>6sub>

    Isotope-Labeled Compounds Others
    Naphthalene-2,6-dicarboxylic acid-d6 is the deuterium labeled Naphthalene-2,6-dicarboxylic acid[1].
    Naphthalene-2,6-dicarboxylic acid-d6
  • HY-B0715S

    BL-191-d<sub>6sub>; PTX-d<sub>6sub>; Oxpentifylline-d<sub>6sub>

    Phosphodiesterase (PDE) Autophagy HIV Cardiovascular Disease Cancer
    Pentoxifylline-d6 is the deuterium labeled Pentoxifylline. Pentoxifylline (BL-191), a haemorheological agent, is an orally active non-selective phosphodiesterase (PDE) inhibitor, with immune modulation, anti-inflammatory, hemorheological, anti-fibrinolytic and anti-proliferation effects. Pentoxifylline can be used for the research of peripheral vascular disease, cerebrovascular disease and a number of other conditions involving a defective regional microcirculation[1][2][3].
    Pentoxifylline-d6
  • HY-15494S1

    AXL1717-d<sub>6sub>; Picropodophyllotoxin-d<sub>6sub>; PPP-d<sub>6sub>

    Isotope-Labeled Compounds IGF-1R Apoptosis Endocrinology Cancer
    Picropodophyllin-d6 (AXL1717-d6) is deuterium labeled Picropodophyllin. Picropodophyllin (AXL1717) is a selective insulin-like growth factor-1 receptor (IGF-1R) inhibitor with an IC50 of 1 nM.
    Picropodophyllin-d6
  • HY-B1873S

    DMDT-d<sub>6sub>; Methoxcide-d<sub>6sub>; Methoxy-DDT-d<sub>6sub>

    Isotope-Labeled Compounds Others
    Methoxychlor-d6 is the deuterium labeled Methoxychlor[1].
    Methoxychlor-d6
  • HY-119695AS

    Tenivastatin-d<sub>6sub> ammonium

    Isotope-Labeled Compounds Endogenous Metabolite Cardiovascular Disease
    Simvastatin acid-d6 (ammonium)mis the deuterium labeled Simvastatin acid ammonium. Simvastatin ammonium is an active metabolite of simvastatin lactone mediated by CYP3A4/5 in the intestinal wall and liver (pKa=5.5). Simvastatin ammonium reduces indoxyl sulfate-mediated reactive oxygen species and modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 gene[1].
    Simvastatin acid-d6 ammonium
  • HY-N0067S

    4-Aminobutyric acid-d<sub>6sub>

    GABA Receptor Endogenous Metabolite Neurological Disease
    γ-Aminobutyric acid-d6 is the deuterium labeled γ-Aminobutyric acid. γ-Aminobutyric acid (4-Aminobutyric acid) is a major inhibitory neurotransmitter in the adult mammalian brain[1][2], binding to the ionotropic GABA receptors (GABAA receptors) and metabotropic receptors (GABAB receptors)[2].
    γ-Aminobutyric acid-d6
  • HY-B1850S

    Inpool-d<sub>6sub>; MON 12000-d<sub>6sub>; Manage-d<sub>6sub>

    Isotope-Labeled Compounds Herbicide Others
    Halosulfuron-methyl-d6 (Inpool-d6) is deuterium labeled Halosulfuron-methyl. Halosulfuron-methyl is a pyrazole sulfonylurea herbicide .
    Halosulfuron-methyl-d6
  • HY-N1214S

    Super Squalene-d<sub>6sub>; trans-Squalene-d<sub>6sub>; AddaVax-d<sub>6sub>

    Isotope-Labeled Compounds Others
    Squalene-d6 is a deuterium labeled Squalene. Squalene (Super Squalene) is an intermediate product in the synthesis of cholesterol, and shows several pharmacological properties such as hypolipidemic, hepatoprotective, antiatherosclerotic, cardioprotective, antioxidant, and antitumour activity .
    Squalene-d6
  • HY-N0537S9

    D-(+)-Xylose-d<sub>6sub>; (+)-Xylose-d<sub>6sub>; Wood sugar-d<sub>6sub>

    Isotope-Labeled Compounds Endogenous Metabolite Others
    Xylose-d6 is the deuterium labeled Xylose.
    Xylose-d6
  • HY-B0696S

    NO050328-d<sub>6sub>; NO328-d<sub>6sub>; TGB-d<sub>6sub>

    Isotope-Labeled Compounds GABA Receptor Neurological Disease
    Tiagabine-d6 (NO050328-d6) is deuterium labeled Tiagabine. Tiagabine (NO050328) is a potent and selective GABA reuptake inhibitor, used as an anticonvulsant agent, with IC50s of 67, 446 and 182 nM for [ 3H]GABA uptake in Synaptosomes, Neurons and Glia, respectively .
    Tiagabine-d6
  • HY-76542S

    Ergocalciferol-d<sub>6sub>; Calciferol-d<sub>6sub>; Ercalciol-d<sub>6sub>

    Isotope-Labeled Compounds VD/VDR Endogenous Metabolite Metabolic Disease
    Vitamin D2-d6 is the deuterium labeled Vitamin D2. Vitamin D2 (Ergocalciferol), drived from plant sources or dietary supplements, could be used as supplement of Vitamin D[1][2].
    Vitamin D2-d6
  • HY-16069S

    Irbinitinib-d<sub>6sub>; ARRY-380-d<sub>6sub>; ONT-380-d<sub>6sub>

    Isotope-Labeled Compounds EGFR Cancer
    Tucatinib-d6 (Irbinitinib-d6) is deuterium labeled Tucatinib. Tucatinib (Irbinitinib) is a potent, orally active and selective HER2 inhibitor with an IC50 of 8 nM .
    Tucatinib-d6
  • HY-W700392

    IMPDH Cancer
    IMPDH-IN-2 (compound 2) is an inhibitor of inosine monophosphate dehydrogenase (IMPDH) with IC50 for IMPDH I and IMPDH II >Values are 0.15 and 0.17 μM, respectively. IMPDH-IN-2 has antitumor activity .
    IMPDH-IN-2
  • HY-41681S

    1-Chloro-6-hexanol-d<sub>6sub>; 1-Chloro-6-hydroxyhexane-d<sub>6sub>; 6-Chlorohexanol-d<sub>6sub>

    Isotope-Labeled Compounds Others
    6-Chloro-1-hexanol-d6 is the deuterium labeled 6-Chloro-1-hexanol[1].
    6-Chloro-1-hexanol-d6
  • HY-W019596S

    PI-EDB-d<sub>6sub>; Parbenate-d<sub>6sub>; Photoinitiator EDAB-d<sub>6sub>; Quantacure EPD-d<sub>6sub>; SB-PI 704-d<sub>6sub>

    Isotope-Labeled Compounds Others
    Ethyl 4-(dimethylamino)benzoate-d6 (PI-EDB-d6) is deuterium labeled Ethyl 4-(dimethylamino)benzoate .
    Ethyl 4-(dimethylamino)benzoate-d6
  • HY-50896S

    CP-358774-d<sub>6sub>; NSC 718781-d<sub>6sub>; OSI-774-d<sub>6sub>

    EGFR Cancer
    Erlotinib-d6 (CP-358774 D6) is a deuterium labeled Erlotinib (CP-358774). Erlotinib is a directly acting inhibitor EGFR tyrosine kinase inhibitor with an IC50 of 2 nM for human EGFR[1]. Erlotinib-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Erlotinib-d6
  • HY-13011S1

    CH5424802-d<sub>6sub>; RO5424802-d<sub>6sub>; AF802-d<sub>6sub>

    Isotope-Labeled Compounds Anaplastic lymphoma kinase (ALK) Cancer
    Alectinib-d6 is deuterium labeled Alectinib. Alectinib (CH5424802) is a potent, selective, and orally available ALK inhibitor with an IC50 of 1.9 nM and a Kd value of 2.4 nM (in an ATP-competitive manner), and also inhibits ALK F1174L and ALK R1275Q with IC50s of 1 nM and 3.5 nM, respectively[1]. Alectinib demonstrates effective central nervous system (CNS) penetration[2].
    Alectinib-d6

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