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Indole-3-acetic acid-d<sub>7</sub>

" in MedChemExpress (MCE) Product Catalog:

4148

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14

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36

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1

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22

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11

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4026

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4

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17

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Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-18569S3
    3-Indoleacetic acid-d7

    Indole-3-acetic acid-d<sub>7sub>; 3-IAA-d<sub>7sub>

    		 Isotope-Labeled Compounds Endogenous Metabolite Metabolic Disease
    3-Indoleacetic acid-d7 is the deuterium labeled 3-Indoleacetic acid (HY-18569). 3-Indoleacetic acid (Indole-3-acetic acid) is the most common natural plant growth hormone of the auxin class. It can be added to cell culture medium to induce plant cell elongation and division .
    3-Indoleacetic acid-d7
  • HY-18569S1
    3-Indoleacetic acid-d4

    Indole-3-acetic acid-d<sub>4sub>; 3-IAA-d<sub>4sub>

    		 Isotope-Labeled Compounds Molecular Glues Endogenous Metabolite Metabolic Disease
    3-Indoleacetic acid-d4 (Indole-3-acetic acid-d4; 3-IAA-d4) is the deuterium labeled 3-Indoleacetic acid (HY-18569) . 3-Indoleacetic acid (Indole-3-acetic acid) is the most common natural plant growth hormone of the auxin class. It can be added to cell culture medium to induce plant cell elongation and division .
    3-Indoleacetic acid-d4
  • HY-18569A
    3-Indoleacetic acid sodium
    5 Publications Verification

    Indole-3-acetic acid sodium; 3-IAA sodium

    		 Endogenous Metabolite Metabolic Disease
    3-Indoleacetic acid (Indole-3-acetic acid) sodium is an IAA hormone and growth regulator that can promote plant nutritional growth through processes such as cell expansion, differentiation, morphogenesis, and organogenesis .
    3-Indoleacetic acid sodium
  • HY-18569S4
    3-Indoleacetic acid-13C6

    Indole-3-acetic acid-13C<sub>6sub>; 3-IAA-13C<sub>6sub>

    		 Isotope-Labeled Compounds Endogenous Metabolite Metabolic Disease
    3-Indoleacetic acid- 13C6 is the 13C labeled 3-Indoleacetic acid (HY-18569). 3-Indoleacetic acid (Indole-3-acetic acid) is the most common natural plant growth hormone of the auxin class. It can be added to cell culture medium to induce plant cell elongation and division .
    3-Indoleacetic acid-13C6
  • HY-18569S2
    3-Indoleacetic acid-2,2-d2

    Indole-3-acetic acid-2,2-d<sub>2sub>; 3-IAA-2,2-d<sub>2sub>

    		 Isotope-Labeled Compounds Endogenous Metabolite Metabolic Disease
    3-Indoleacetic acid-2,2-d2 is the deuterium labeled 3-Indoleacetic acid (HY-18569). 3-Indoleacetic acid (Indole-3-acetic acid) is the most common natural plant growth hormone of the auxin class. It can be added to cell culture medium to induce plant cell elongation and division .
    3-Indoleacetic acid-2,2-d2
  • HY-W016784
    Indole-3-acetamide
    1 Publications Verification

    		 Endogenous Metabolite Others
    Indole-3-acetamide is a biosynthesis intermediate of indole-3-acetic acid (HY-18569). Indole-3-acetic acid is the most common natural plant growth hormone of the auxin class .
    Indole-3-acetamide
  • HY-18569S
    3-Indoleacetic acid-d5
    1 Publications Verification

    Indole-3-acetic acid-d<sub>5sub>; 3-IAA-d<sub>5sub>

    		 Endogenous Metabolite Isotope-Labeled Compounds Metabolic Disease
    3-Indoleacetic acid-d5 is the deuterium labeled 3-Indoleacetic acid (HY-18569). 3-Indoleacetic acid-d5 can be used as internal standard for assay of IAA releases by alkaline hydrolysis of ester and amide conjugates .
    3-Indoleacetic acid-d5
  • HY-18569
    3-Indoleacetic acid
    5 Publications Verification

    Indole-3-acetic acid; 3-IAA

    		 Endogenous Metabolite Metabolic Disease
    3-Indoleacetic acid is is an IAA hormone and growth regulator that can promote plant nutritional growth through processes such as cell expansion, differentiation, morphogenesis, and organogenesis .
    3-Indoleacetic acid
  • HY-W016784S
    Indole-3-acetamide-d5

    		Endogenous Metabolite Others
    Indole-3-acetamide-d5 is the deuterium labeled Indole-3-acetamide[1]. Indole-3-acetamide is a biosynthesis intermediate of indole-3-acetic acid (HY-18569). Indole-3-acetic acid is the most common natural plant growth hormone of the auxin class[2].
    Indole-3-acetamide-d5
  • HY-18569R
    3-Indoleacetic acid (standard)

    Indole-3-acetic acid (standard); 3-IAA (standard)

    		 Molecular Glues Endogenous Metabolite Others
    3-Indoleacetic acid (Standard) is the analytical standard of 3-Indoleacetic acid. This product is intended for research and analytical applications. 3-Indoleacetic acid is is an IAA hormone and growth regulator that can promote plant nutritional growth through processes such as cell expansion, differentiation, morphogenesis, and organogenesis .
    3-Indoleacetic acid (standard)
  • HY-W588263S1
    Indole-3-acetyl glutamate-d4

    IAGlu-d<sub>4sub>

    		 Isotope-Labeled Compounds Others Others
    Indole-3-acetyl glutamate-d4 (IAGlu-d4) is deuterium labeled Indole-3-acetyl glutamate. Indole-3-acetyl glutamate (IAGlu) is a derivative of the plant hormone indole-3-acetic acid (IAA). As a conjugated form of IAA, Indole-3-acetyl glutamate involves in the transport, storage, and homeostatic regulation of IAA within the plant. Indole-3-acetyl glutamate can be used for research into the effects of plant hormones on the growth and development of plants .
    Indole-3-acetyl glutamate-d4
  • HY-W007376S
    Indole-3-carboxaldehyde-13C

    3-FormylIndole-13C<sub>3sub>

    		 Isotope-Labeled Compounds Endogenous Metabolite Others
    Indole-3-carboxaldehyde- 13C (3-Formylindole- 13C) is a 13C labeled Indole-3-carboxaldehyde (HY-W007376). Indole-3-carboxaldehyde (3-Formylindole), a banlangen extract, is the product of the oxidative degradation of indole-3-acetic acid (IAA) by crude enzyme preparations from etiolated pea seedlings. Indole-3-carboxaldehyde (3-Formylindole) is a biochemical used to prepare analogs of the indole phytoalexin cyclobrassinin .
    Indole-3-carboxaldehyde-13C
  • HY-W750674
    Indole-3-carboxaldehyde-13C8

    3-FormylIndole-C13C<sub>8sub>

    		 Isotope-Labeled Compounds Inflammation/Immunology
    Indole-3-carboxaldehyde- 13C8 (3-Formylindole- 13C8) is the 13C-labeled Indole-3-carboxaldehyde (HY-W007376). Indole-3-carboxaldehyde, a banlangen extract, is the product of the oxidative degradation of indole-3-acetic acid (IAA) by crude enzyme preparations from etiolated pea seedlings. Indole-3-carboxaldehyde is a biochemical used to prepare analogs of the indole phytoalexin cyclobrassinin. Indole-3-carboxaldehyde also enhances the epithelial barrier and anti-inflammatory activity in the intestinal tract .
    Indole-3-carboxaldehyde-13C8
  • HY-112730
    PEO-IAA
    5 Publications Verification

    2-(1H-Indol-3-yl)-4-oxo-4-phenyl-butyric acid

    		 Others Others
    PEO-IAA is an indole-3-acetic acid (IAA) antagonist. PEO-IAA is an auxin antagonist that binds to transport inhibitor response 1/auxin signaling F-box proteins (TIR1/AFBs).
    PEO-IAA
  • HY-18573
    Naxillin

    		Others Others
    Naxillin is a non-auxin-like molecule, which can promote the lateral root branching in the basal meristem of the root, through the conversion of the auxin precursor indole-3-butyric acid (IBA) to the active auxin indole-3-acetic acid (IAA) .
    Naxillin
  • HY-W006267
    4-Chloroindole-3-acetic acid

    4-Cl-IAA

    		 Endogenous Metabolite Others
    4-Chloroindole-3-acetic acid (4-Cl-IAA) is a chlorinated analogue of indole-3-acetic acid (IAA) (HY-18569) auxin that functions as a plant hormone, which is found in the seeds of Medicago truncatula、Melilotus indicus and Trifolium .
    4-Chloroindole-3-acetic acid
  • HY-146227
    DNA topoisomerase II inhibitor 1

    		Topoisomerase Apoptosis Cancer
    DNA topoisomerase II inhibitor 1 (compound 8ed) is a potent DNA topoisomerase II inhibitor. DNA topoisomerase II inhibitor 1 shows anti-proliferative activity. DNA topoisomerase II inhibitor 1 induces apoptosis and cell cycle arrest at sub G1 phase .
    DNA topoisomerase II inhibitor 1
  • HY-RS13999
    SUB1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    SUB1 Human Pre-designed siRNA Set A contains three designed siRNAs for SUB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    SUB1 Human Pre-designed siRNA Set A
    SUB1 Human Pre-designed siRNA Set A
  • HY-168496
    Herbicidal agent 8

    		Herbicide Phytohormone Others
    Herbicidal agent 8 (Compound 9w) targets the auxin indole-3-acetic acid (IAA, IC50=4.389 μM), disrupting the physiological activities of plant cells and eventually causing plant death. Herbicidal agent 8 exhibits herbicidal activity against broadleaf weeds and grass weeds .
    Herbicidal agent 8
  • HY-116425
    N-1-Naphthylphthalamic acid
    1 Publications Verification

    Alanap 1

    		 Herbicide Others
    N-1-Naphthylphthalamic acid (Alanap 1) is a modulator of polar auxin transport that competes with auxin (indole-3-acetic acid, IAA) for membrane binding sites. N-1-Naphthylphthalamic acid also disrupts maize leaf initiation, KNOX protein regulation, and leaf margin formation .
    N-1-Naphthylphthalamic acid
  • HY-N13014
    Indole-3-acetyl β-D-glucopyranose

    		Others Others
    Indole-3-acetyl β-D-glucopyranose is a glucose esterified derivative of the plant hormone indole-3-acetic acid (IAA). Indole-3-acetyl β-D-glucopyranose is involved in regulating plant growth and can be used to study the metabolism and regulatory mechanisms of plant hormones .
    Indole-3-acetyl β-D-glucopyranose
  • HY-B1804S1
    Tricaprilin-d50

    Trioctanoin-d<sub>50sub>; Glyceryl trioctanoate-d<sub>50sub>

    		 Isotope-Labeled Compounds Endogenous Metabolite Neurological Disease Inflammation/Immunology
    Tricaprilin-d50 (Trioctanoin-d50 is the deuterium labeled Tricaprilin (HY-B1804). Tricaprilin is an orally active and well tolerated ketogenic agent that safely induces ketosis. Tricaprilin restores brain electrical activity and metabolism to help counteract neuroinflammation in migraine. Tricaprilin is promising for research of migraine prevention and Alzheimer’s disease (AD). Tricaprilin is a pure C8 medium chain triglyceride (MCT) [3].
    Tricaprilin-d50
  • HY-B1804S2
    Tricaprilin-d15

    Trioctanoin-d<sub>15sub>; Glyceryl trioctanoate-d<sub>15sub>

    		 Isotope-Labeled Compounds Endogenous Metabolite Neurological Disease Inflammation/Immunology
    Tricaprilin-d15 (Trioctanoin-d15 is the deuterium labeled Tricaprilin (HY-B1804). Tricaprilin is an orally active and well tolerated ketogenic agent that safely induces ketosis. Tricaprilin restores brain electrical activity and metabolism to help counteract neuroinflammation in migraine. Tricaprilin is promising for research of migraine prevention and Alzheimer’s disease (AD). Tricaprilin is a pure C8 medium chain triglyceride (MCT) [3].
    Tricaprilin-d15
  • HY-W588263
    Indole-3-acetyl glutamate

    IAGlu

    		 Drug Derivative Others
    Indole-3-acetyl glutamate (IAGlu) is a derivative of the plant hormone indole-3-acetic acid (IAA). As a conjugated form of IAA, Indole-3-acetyl glutamate involves in the transport, storage, and homeostatic regulation of IAA within the plant. Indole-3-acetyl glutamate can be used for research into the effects of plant hormones on the growth and development of plants .
    Indole-3-acetyl glutamate
  • HY-W007376
    Indole-3-carboxaldehyde
    2 Publications Verification

    3-FormylIndole

    		 Endogenous Metabolite Others
    Indole-3-carboxaldehyde (3-Formylindole), a banlangen extract, is the product of the oxidative degradation of indole-3-acetic acid (IAA) by crude enzyme preparations from etiolated pea seedlings. Indole-3-carboxaldehyde is a biochemical used to prepare analogs of the indole phytoalexin cyclobrassinin. Indole-3-carboxaldehyde also enhances the epithelial barrier and anti-inflammatory activity in the intestinal tract .
    Indole-3-carboxaldehyde
  • HY-116425R
    N-1-Naphthylphthalamic acid (Standard)

    		Herbicide Others
    N-1-Naphthylphthalamic acid (Standard) is the analytical standard of N-1-Naphthylphthalamic acid. This product is intended for research and analytical applications. N-1-Naphthylphthalamic acid (Alanap 1) is a modulator of polar auxin transport that competes with auxin (indole-3-acetic acid, IAA) for membrane binding sites. N-1-Naphthylphthalamic acid also disrupts maize leaf initiation, KNOX protein regulation, and leaf margin formation .
    N-1-Naphthylphthalamic acid (Standard)
  • HY-41463S
    4-(Butylamino)benzoic acid-d7

    4-(Butylamino)benzoic acid-d<sub>7sub>; NSC 44300-d<sub>7sub>; p-Butylaminobenzoic acid-d<sub>7sub>

    		 Isotope-Labeled Compounds Others
    4-(Butylamino)benzoic acid-d7 is the deuterium labeled 4-(Butylamino)benzoic acid[1].
    4-(Butylamino)benzoic acid-d7
  • HY-N2334AS
    Glycochenodeoxycholic acid-d7 sodium

    Chenodeoxycholylglycine-d<sub>7sub> (sodium); Sodium glycochenodeoxycholate-d<sub>7sub>

    		 Endogenous Metabolite Apoptosis Cancer
    Glycochenodeoxycholic acid-d7 (sodium) is the deuterium labeled Glycochenodeoxycholic acid (sodium salt). Glycochenodeoxycholic acid sodium salt (Chenodeoxycholylglycine sodium salt) is a bile acid formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. Glycochenodeoxycholic acid sodium salt (Chenodeoxycholylglycine sodium salt) induces hepatocyte apoptosis[1][2].
    Glycochenodeoxycholic acid-d7 sodium
  • HY-N13014S2
    Indole-3-acetyl β-D-glucopyranose-d4

    		Isotope-Labeled Compounds Others
    Indole-3-acetyl β-D-glucopyranose-d4 is deuterium labeled Indole-3-acetyl β-D-glucopyranose. Indole-3-acetyl β-D-glucopyranose is a glucose esterified derivative of the plant hormone indole-3-acetic acid (IAA). Indole-3-acetyl β-D-glucopyranose is involved in regulating plant growth and can be used to study the metabolism and regulatory mechanisms of plant hormones .
    Indole-3-acetyl β-D-glucopyranose-d4
  • HY-15027S4
    5-Aminosalicylic acid-d7

    5-ASA-d<sub>7sub>; Mesalamie-d<sub>7sub>; Mesalazie-d<sub>7sub>

    		 Isotope-Labeled Compounds PPAR PAK Endogenous Metabolite NF-κB Inflammation/Immunology Cancer
    5-Aminosalicylic acid-d7 (5-ASA-d7; Mesalamie-d7; Mesalazie-d7) is deuterium labeled 5-Aminosalicylic Acid. 5-Aminosalicylic acid (Mesalamine) acts as a specific PPARγ agonist and also inhibits p21-activated kinase 1 (PAK1) and NF-κB. 5-Aminosalicylic acid can inhibit the activity of osteopontin (OPN) .
    5-Aminosalicylic acid-d7
  • HY-W017387S3
    α-Ketoisocaproic acid-d7

    4-Methyl-2-oxopentanoate-d<sub>7sub>; 2-Ketoisocaproic acid-d<sub>7sub>

    		 Isotope-Labeled Compounds Others
    α-Ketoisocaproic acid-d7 is the deuterium labeled α-Ketoisocaproic acid[1].
    α-Ketoisocaproic acid-d7
  • HY-10844S1
    Pretomanid-d5

    PA-824-d<sub>5sub>; (S)-PA 824-d<sub>5sub>

    		 Antibiotic Bacterial Isotope-Labeled Compounds Infection Cancer
    Pretomanid-d5 is deuterated labeled Pretomanid (HY-10844). Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 μg/mL.
    Pretomanid-d5
  • HY-P10215
    Ac-{Cpg}-Thr-Ala-{Ala(CO)}-Asp-{Cpg}-NH2

    		Parasite Infection
    Ac-{Cpg}-Thr-Ala-{Ala(CO)}-Asp-{Cpg}-NH2 (compound 40) is a potent Plasmodium subtilisin-like protease 1 (SUB1) inhibitor. SUB1-IN-1 shows IC50 values of 12 nM and 10 nM against P. vivax and P. falciparum SUB1 (Pv- and PfSUB1), respectively .
    Ac-{Cpg}-Thr-Ala-{Ala(CO)}-Asp-{Cpg}-NH2
  • HY-10585AS
    Valproic acid-d7 sodium

    Sodium Valproate-d<sub>7sub>(sodium)

    		 Isotope-Labeled Compounds HDAC Autophagy Mitophagy HIV Notch Endogenous Metabolite Cancer
    Valproic acid-d7 (sodium) is the deuterium labeled Valproic acid (sodium salt). Valproic acid sodium salt (Sodium Valproate) is an HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid sodium salt activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid sodium salt is used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches[1][2].
    Valproic acid-d7 sodium
  • HY-41494S
    O-Toluic acid-d7

    2-Methylbenzoic acid-d<sub>7sub>

    		 Isotope-Labeled Compounds Endogenous Metabolite Others
    O-Toluic acid-d7 is the deuterium labeled o-Toluic acid[1]. o-Toluic acid (2-Methylbenzoic acid) is a benzoic acid substituted by a methyl group at position 2. O-Toluic acid plays a role as a xenobiotic metabolite.
    O-Toluic acid-d7
  • HY-76547S1
    p-Toluic acid-d7

    4-Methylbenzoic acid-d<sub>7sub>

    		 Endogenous Metabolite Others
    p-Toluic acid-d7 is the deuterium labeled p-Toluic acid[1]. p-Toluic acid (4-Methylbenzoic acid) is a substituted benzoic acid and can be used as an intermediate for the synthesis of para-aminomethylbenzoic acid (PAMBA), p-tolunitrile, etc.
    p-Toluic acid-d7
  • HY-N0610S1
    trans-Cinnamic acid-d7

    trans-3-Phenylacrylic acid-d<sub>7sub>

    		 Bacterial Endogenous Metabolite Infection
    trans-Cinnamic acid-d7 is the deuterium labeled trans-Cinnamic acid[1]. trans-Cinnamic acid is a natural antimicrobial, with minimal inhibitory concentration (MIC) of 250 μg/mL against fish pathogen A. sobria, SY-AS1[2].
    trans-Cinnamic acid-d7
  • HY-107327S
    Carazolol-d7

    (±)-Carazolol-d<sub>7sub>; DL-Carazolol-d<sub>7sub>; Suacron-d<sub>7sub>

    		 Adrenergic Receptor Others
    Carazolol-d7 is the deuterium labeled Carazolol[1].
    Carazolol-d7
  • HY-N0006S
    Demethoxycurcumin-d7

    Curcumin II-d<sub>7sub>; Desmethoxycurcumin-d<sub>7sub>; Monodemethoxycurcumin-d<sub>7sub>

    		 Isotope-Labeled Compounds Apoptosis Autophagy Bacterial Inflammation/Immunology Cancer
    Demethoxycurcumin-d7 is the deuterium labeled Demethoxycurcumin. Demethoxycurcumin(Curcumin II), a major active curcuminoid, possess anti-inflammatory properties; also exert cytotoxic effects in human cancer cells via induction of apoptosis.
    Demethoxycurcumin-d7
  • HY-B0584S2
    Travoprost-d7

    Fluprostenol isopropyl ester-<sub>7sub>; AL6221-<sub>7sub>; Flu-Ipr-<sub>7sub>

    		 Isotope-Labeled Compounds Prostaglandin Receptor Cardiovascular Disease Endocrinology
    Travoprost-d7 (Fluprostenol isopropyl ester-d7) is deuterium labeled Travoprost. Travoprost (Fluprostenol isopropyl ester), an isopropyl ester proagent, is a high affinity, selective FP prostaglandin full receptor agonist. Travoprost has the ocular hypotensive efficacy and has the potential for glaucoma and ocular hypertension .
    Travoprost-d7
  • HY-66005S2
    Acetaminophen-d7

    Paracetamol-d<sub>7sub>; 4-Acetamidophenol-d<sub>7sub>; 4'-Hydroxyacetanilide-d<sub>7sub>

    		 COX Endogenous Metabolite Histone Acetyltransferase Inflammation/Immunology
    Acetaminophen-d7 is the deuterium labeled Acetaminophen. Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM; is a widely used antipyretic and analgesic agent. Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor.
    Acetaminophen-d7
  • HY-B0389S6
    D-Glucose-d7

    Glucose-d<sub>7sub>; D-(+)-Glucose-d<sub>7sub>; Dextrose-d<sub>7sub>

    		 Isotope-Labeled Compounds Endogenous Metabolite Metabolic Disease
    D-Glucose-d77 is the deuterium labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].
    D-Glucose-d7
  • HY-D0711S2
    Indocyanine green-d7

    Foxgreen-d<sub>7sub>; IC Green-d<sub>7sub>; Cardiogreen-d<sub>7sub>

    		 Isotope-Labeled Compounds Fluorescent Dye Others
    Indocyanine green-d7 (Foxgreen-d7) is the deuterium labeled Indocyanine green (HY-D0711). Indocyanine green is a low toxicic fluorescent agent that has been widely used in medical diagnostics, such as determining cardiac output, hepatic function, and liver blood flow, and for ophthalmic angiography .
    Indocyanine green-d7
  • HY-107352S
    Fosfenopril-d7

    Fosinoprilat-d<sub>7sub>; Fosinoprilic acid-d<sub>7sub>; SQ 27519-d<sub>7sub>

    		 Angiotensin-converting Enzyme (ACE) Interleukin Related NF-κB TNF Receptor Toll-like Receptor (TLR) Isotope-Labeled Compounds Others
    Fosfenopril-d7 is deuterium labeled Fosfenopril.
    Fosfenopril-d7
  • HY-W012722BS
    4-Methyl-2-oxopentanoic acid-d7 sodium

    α-Ketoisocaproic acid-d<sub>7sub> sodium

    		 Endogenous Metabolite Isotope-Labeled Compounds Neurological Disease Metabolic Disease
    4-Methyl-2-oxopentanoic acid-d7 (α-Ketoisocaproic acid-d7) sodium is the deuterium labeled 4-Methyl-2-oxopentanoic acid (HY-W012722).4-Methyl-2-oxopentanoic acid is a metabolite of L-leucine and is involved in energy metabolism. 4-Methyl-2-oxopentanoic acid increases endoplasmic reticulum stress, promotes lipid accumulation in preadipocytes and insulin resistance by impairing mTOR and autophagy signaling pathways .
    4-Methyl-2-oxopentanoic acid-d7 sodium
  • HY-12057S1
    Vemurafenib-d7

    PLX4032-d<sub>7sub>; RG7204-d<sub>7sub>; RO5185426-d<sub>7sub>

    		 Isotope-Labeled Compounds Raf Autophagy Cancer
    Vemurafenib-d7 is deuterium labeled Vemurafenib. Vemurafenib (PLX4032) is a first-in-class, selective, potent inhibitor of B-RAF kinase, with IC50s of 31 and 48 nM for RAFV600E and c-RAF-1, respectively[1][4]. Vemurafenib induces cell autophagy[5].
    Vemurafenib-d7
  • HY-15149S2
    Romidepsin-d7

    FK 228-d<sub>7sub>; FR 901228-d<sub>7sub>; NSC 630176-d<sub>7sub>

    		 Isotope-Labeled Compounds HDAC Apoptosis Cancer
    Romidepsin-d7 (FK 228-d7) is deuterium labeled Romidepsin. Romidepsin (FK 228) is a Histone deacetylase (HDAC) inhibitor with anti-tumor activities. Romidepsin (FK 228) inhibits HDAC1, HDAC2, HDAC4, and HDAC6 with IC50s of 36 nM, 47 nM, 510 nM and 1.4 μM, respectively . Romidepsin (FK 228) is produced by Chromobacterium violaceum, induces cell G2/M phase arrest and apoptosis .
    Romidepsin-d7
  • HY-Y0376S
    DMPA-d7

    Bis-MPA-d<sub>7sub>; Dimethylolpropionic acid-d<sub>7sub>; Nikkamer PA-d<sub>7sub>

    		 Isotope-Labeled Compounds Others
    DMPA-d7 is the deuterium labeled DMPA[1].
    DMPA-d7
  • HY-Y1309S1
    1-Naphthol-d7

    Furro ER-d<sub>7sub>; NSC 9586-d<sub>7sub>; Nako TRB-d<sub>7sub>

    		 Isotope-Labeled Compounds Others
    1-Naphthol-d7 is the deuterium labeled Naphthol .
    1-Naphthol-d7
  • HY-W700392
    IMPDH-IN-2

    		IMPDH Cancer
    IMPDH-IN-2 (compound 2) is an inhibitor of inosine monophosphate dehydrogenase (IMPDH) with IC50 for IMPDH I and IMPDH II >Values are 0.15 and 0.17 μM, respectively. IMPDH-IN-2 has antitumor activity .
    IMPDH-IN-2

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