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Lactic acid-d<sub>3</sub>

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Oligonucleotides:	Pre-designed siRNA Sets (1) Polymers (5) siRNAs (1)

3393

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Isotope-Labeled Compounds

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Targets Recommended: Amino acid Transporter Amino Acid Derivatives Hydroxycarboxylic Acid Receptor (HCAR) Free Fatty Acid Receptor Fatty Acid Synthase (FASN) Apical Sodium-Dependent Bile Acid Transporter P-glycoprotein G protein-coupled Bile Acid Receptor 1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B2227BS1

Lactate-d3 sodium Lactic acid-d<sub>3sub> sodium	Isotope-Labeled Compounds	Others
Lactate-d₃ (sodium) is the deuterium labeled Lactate sodium. Lactate sodium is the product of glycogenolysis and glycolysis. Lactate sodium functions in a variety of biochemical processes[1][2].

HY-Y0479AS

*L-Lactic* acid-13C3 sodium** (S)-2-hydroxypropanoic-¹³C<sub>3sub> sodium	Antibiotic Endogenous Metabolite Bacterial Isotope-Labeled Compounds	Metabolic Disease
L-Lactic acid- ¹³C₃ (sodium) is the ¹³C labeled L-Lactic acid. L-Lactic acid- ¹³C₃ sodium can be used for lactate metabolism research[1].

HY-B0302AS

Etidronic acid-d3 disodium Etidronate-d<sub>3sub> disodium; HEDPA-d<sub>3sub> disodium; HEDP-d<sub>3sub> disodium	Apoptosis Isotope-Labeled Compounds	Others
Etidronic acid-d₃ (disodium) is the deuterium labeled Etidronic acid disodium[1].

HY-103395S

Methylmalonic acid-d3 Methylpropanedioic acid-d<sub>3sub>; Methylmalonate-d<sub>3sub>	Endogenous Metabolite	Cancer
Methylmalonic acid-d₃ is the deuterium labeled Methylmalonic acid. Methylmalonic acid (Methylmalonate) is an indicator of Vitamin B-12 deficiency in cancer[1][2].

HY-18569S

3-Indoleacetic acid-d5 1 Publications Verification Indole-3-acetic acid-d<sub>5sub>; 3-IAA-d<sub>5sub>	Endogenous Metabolite Isotope-Labeled Compounds	Others
3-Indoleacetic acid-d₅ is the deuterium labeled 3-Indoleacetic acid. 3-Indoleacetic acid-d₅ can be used as internal standard for assay of IAA releases by alkaline hydrolysis of ester and amide conjugates[1].

HY-RS13999

SUB1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SUB1 Human Pre-designed siRNA Set A contains three designed siRNAs for SUB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SUB1 Human Pre-designed siRNA Set A SUB1 Human Pre-designed siRNA Set A

HY-146227

DNA topoisomerase II inhibitor 1	Topoisomerase Apoptosis	Cancer
DNA topoisomerase II inhibitor 1 (compound 8ed) is a potent DNA topoisomerase II inhibitor. DNA topoisomerase II inhibitor 1 shows anti-proliferative activity. DNA topoisomerase II inhibitor 1 induces apoptosis and cell cycle arrest at sub G1 phase .

HY-13777S1

Zoledronic acid-d3 Zoledronate-d<sub>3sub>; CGP 42446-d<sub>3sub>; CGP42446A-d<sub>3sub>; ZOL 446-d<sub>3sub>	Isotope-Labeled Compounds	Others
Zoledronic acid-d3 is the deuterium labeled Zoledronic acid .

HY-N0156S

Oleanolic acid-d3 Oleanic acid-d<sub>3sub>; Caryophyllin-d<sub>3sub>	Autophagy HIV Endogenous Metabolite	Cancer
Oleanolic acid-d₃ is the deuterium labeled Oleanolic Acid[1]. Oleanolic acid (Caryophyllin) is a natural compound from plants with anti-tumor activities[2].

HY-75087S

(R)-Pyrrolidine-2-carboxylic acid-d3 (+)-(R)-Proline-d<sub>3sub>; (R)-(+)-Proline-d<sub>3sub>; (R)-2-Carboxypyrrolidine-d<sub>3sub>; (R)-Proline-d<sub>3sub>	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
(R)-Pyrrolidine-2-carboxylic acid-d₃ is the deuterium labeled (R)-pyrrolidine-2-carboxylic acid. (R)-pyrrolidine-2-carboxylic acid is an endogenous metabolite.

HY-15027S

5-Aminosalicylic Acid-d3 hydrochloride Mesalamine-d<sub>3sub> hydrochloride; 5-ASA-d<sub>3sub> hydrochloride; Mesalazine-d<sub>3sub> hydrochloride	Isotope-Labeled Compounds PPAR PAK NF-κB Endogenous Metabolite	Inflammation/Immunology Cancer
5-Aminosalicylic Acid-d₃ (hydrochloride) is the deuterium labeled 5-Aminosalicylic Acid. 5-Aminosalicylic acid (Mesalamine) hydrochloride acts as a specific PPARγ agonist and also inhibits p21-activated kinase 1 (PAK1) and NF-κB.

HY-W154267S

3-Aminoisobutyric acid-d3 hydrochloride β-Aminoisobutyric acid-d<sub>3sub> hydrochloride; BAIBA-d<sub>3sub> hydrochloride	Isotope-Labeled Compounds	Others
3-Aminoisobutyric acid-d₃ (hydrochloride) is the deuterium labeled DL-Histidine[1].

HY-W004282S1

Undecanoic acid-d3 Undecanoate-d<sub>3sub>; Hendecanoic acid-d<sub>3sub>	Isotope-Labeled Compounds Fungal Endogenous Metabolite	Infection
Undecanoic acid-d₃ is the deuterium labeled Undecanoic acid. Undecanoic acid (Undecanoate) is a monocarboxylic acid with antimycotic property, which inhibits the production of exocellular keratinase, lipase and the biosynthesis of several phospholipids in T. rubrum[1].

HY-I0746S

3-Aminobenzoic acid-d4 m-Aminobenzoic acid-d<sub>4sub>; 3ABA-d<sub>4sub>	Endogenous Metabolite	Others
3-Aminobenzoic acid-d₄ is the deuterium labeled 3-Aminobenzoic acid[1].

HY-15027S1

5-Aminosalicylic acid-d3 Mesalamine-d<sub>3sub>; 5-ASA-d<sub>3sub>; Mesalazine-d<sub>3sub>	Isotope-Labeled Compounds Endogenous Metabolite NF-κB PAK PPAR	Inflammation/Immunology Cancer
5-Aminosalicylic acid-d₃ is the deuterium labeled 5-Aminosalicylic Acid. 5-Aminosalicylic acid (Mesalamine) acts as a specific PPARγ agonist and also inhibits p21-activated kinase 1 (PAK1) and NF-κB[1][2][3][4].

HY-113099S

Indolelactic acid-d5 Indole-3-Lactic acid-d<sub>5sub>	Endogenous Metabolite	Others
Indolelactic acid-d₅ is the deuterium labeled Indolelactic acid. Indolelactic acid is a tryptophan (Trp) catabolite in Azotobacter vinelandii cultures.

HY-13318S

Oseltamivir acid-d3 Maximum Cited Publications 56 Publications Verification GS 4071-d<sub>3sub>; Ro 64-0802-d<sub>3sub>; Oseltamivir carboxylate-d<sub>3sub>	Influenza Virus	Infection
Oseltamivir acid-d₃ is a deuterium labeled Oseltamivir acid. Oseltamivir acid, the active metabolite of Oseltamivir phosphate, is an orally bioavailable, potent and selective inhibitor of influenza virus neuraminidase (IC50=2 nM) with activity against both influenza A and B viruses[1][2].

HY-Y1311S

Malic acid-d3 Hydroxybutanedioic acid-d<sub>3sub>; E 296-d<sub>3sub>	Endogenous Metabolite	Others
Malic acid-d₃ is the deuterium labeled Malic acid. Malic acid (Hydroxybutanedioic acid) is a dicarboxylic acid that is naturally found in fruits such as apples and pears. It plays a role in many sour or tart foods[1][2].

HY-Y0479R

*L-Lactic* acid (Standard)**	Bacterial Endogenous Metabolite Antibiotic	Infection
L-Lactic acid (Standard) is the analytical standard of L-Lactic acid. This product is intended for research and analytical applications. L-Lactic acid is a buildiing block which can be used as a precursor for the production of the bioplastic polymer poly-lactic acid.

HY-Y0084S

3,4,5-Trimethoxybenzoic acid-d3 Eudesmic acid-d<sub>3sub>; Trimethylgallic acid-d<sub>3sub>	Isotope-Labeled Compounds	Others
3,4,5-Trimethoxybenzoic acid-d₃ is the deuterium labeled 3,4,5-Trimethoxybenzoic acid[1]. 3,4,5-Trimethoxybenzoic acid (Eudesmic acid;Trimethylgallic Acid) is a benzoic acid derivative. A building block in medicine and organic synthesis.

HY-158995S1

3-Epiglycyrrhetinic acid-d3 3α-Glycyrrhetic acid-d<sub>3sub>	Isotope-Labeled Compounds	Others
3-Epiglycyrrhetinic acid-d3 (3α-Glycyrrhetic acid-d3) is the deuterium-labeled 3-Epiglycyrrhetinic acid. 3-Epiglycyrrhetinic acid is a derivative of glycyrrhetic acid. Glycyrrhetic acid and its derivative are considered to have anti-inflammatory, anti-ulcer, and antiviral activities .

HY-Y1069S

(S)-Malic acid-d3 (S)-Hydroxybutanedioic acid-d<sub>3sub>; (S)-E 296-d<sub>3sub>; L-Malic acid-d<sub>3sub>	Endogenous Metabolite	Metabolic Disease
(S)-Malic acid-d₃ is the deuterium labeled (S)-Malic acid. (S)-Malic acid ((S)-2-Hydroxysuccinic acid) is a dicarboxylic acid in naturally occurring form, contributes to the pleasantly sour taste of fruits and is used as a food additive[1][2].

HY-10844S1

Pretomanid-d5 PA-824-d<sub>5sub>; (S)-PA 824-d<sub>5sub>	Antibiotic Bacterial Isotope-Labeled Compounds	Infection Cancer
Pretomanid-d₅ is deuterated labeled Pretomanid (HY-10844). Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 μg/mL.

HY-18569S1

3-Indoleacetic acid-d4 Indole-3-acetic acid-d<sub>4sub>; 3-IAA-d<sub>4sub>	Isotope-Labeled Compounds	Others
3-Indoleacetic acid-d₄ (Indole-3-acetic acid-d₄; 3-IAA-d₄)is the deuterium labeled3-Indoleacetic acid(HY-18569) . 3-Indoleacetic acid (Indole-3-acetic acid) is the most common natural plant growth hormone of the auxin class. It can be added to cell culture medium to induce plant cell elongation and division .

HY-B0421S

Mycophenolic acid-d3 Mycophenolate-d<sub>3sub>	Bacterial Apoptosis Fungal Antibiotic Endogenous Metabolite Isotope-Labeled Compounds Flavivirus	Others
Mycophenolic acid-d₃ is deuterium labeled Mycophenolic acid, which is an an immunosuppresant agent and has potent anti-proliferative activity.

HY-113335S

Trihydroxycholestanoic acid-d3 Coprocholic acid-d<sub>3sub>	Endogenous Metabolite Isotope-Labeled Compounds	Others
Trihydroxycholestanoic acid-d₃ is the deuterium labeled Trihydroxycholestanoic acid[1].

HY-B1053S

Iotalamic acid-d3 Iothalamic acid-d<sub>3sub>	Isotope-Labeled Compounds	Inflammation/Immunology
Iotalamic acid-d₃ is the deuterium labeled Iotalamic acid[1].

HY-15027S3

5-Aminosalicylic acid-d3 disodium Mesalamine-d<sub>3sub> disodium; 5-ASA-d<sub>3sub> disodium; Mesalazine-d<sub>3sub> disodium	PPAR NF-κB Endogenous Metabolite PAK Isotope-Labeled Compounds	Inflammation/Immunology
5-Aminosalicylic acid-d₃ disodium is deuterated labeled 5-Aminosalicylic Acid (HY-15027). 5-Aminosalicylic acid (Mesalamine) acts as a specific PPARγ agonist and also inhibits p21-activated kinase 1 (PAK1) and NF-κB.5-Aminosalicylic acid can inhibit the activity of osteopontin (OPN).

HY-Y1088S3

Hydrocinnamic acid-d5 3-Phenylpropionic acid-d<sub>5sub>; 3-Phenylpropanoic acid-d<sub>5sub>; 3-Phenyl-n-propionic acid-d<sub>5sub>	Endogenous Metabolite	Others
Hydrocinnamic acid-d₅ is the deuterium labeled Hydrocinnamic acid[1]. Hydrocinnamic acid is the major rhizospheric compound with known growth regulatory activities[2].

HY-Y1088S2

Hydrocinnamic acid-d9 3-Phenylpropionic acid-d<sub>9sub>; 3-Phenylpropanoic acid-d<sub>9sub>; 3-Phenyl-n-propionic acid-d<sub>9sub>	Endogenous Metabolite	Others
Hydrocinnamic acid-d₉ is the deuterium labeled Hydrocinnamic acid[1]. Hydrocinnamic acid is the major rhizospheric compound with known growth regulatory activitie[2]s.

HY-113371AS

2-Methylcitric acid-d3 trisodium Methylcitric acid-d<sub>3sub> trisodium	Endogenous Metabolite Isotope-Labeled Compounds	Metabolic Disease
2-Methylcitric acid-d₃ (Methylcitric acid-d₃) trisodium is deuterium-labeled 2-Methylcitric acid (trisodium) (HY-113371A) .

HY-N0384S4

Homovanillic acid-d3-1 Vanilacetic acid-d<sub>3sub>-1	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
Homovanillic acid-d3-1 (Vanilacetic acid-d3-1) is deuterated labeled Homovanillic acid (HY-N0384). Homovanillic acid is a dopamine metabolite associated with aromatic amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and adiponectin reductase deficiency .

HY-18569S3

3-Indoleacetic acid-d7 Indole-3-acetic acid-d<sub>7sub>; 3-IAA-d<sub>7sub>	Endogenous Metabolite Molecular Glues	Others
3-Indoleacetic acid-d₇ is the deuterium labeled 3-Indoleacetic acid[1]. 3-Indoleacetic acid (Indole-3-acetic acid) is the most common natural plant growth hormone of the auxin class. It can be added to cell culture medium to induce plant cell elongation and division.

HY-119695AS2

Simvastatin acid-d3 ammonium Tenivastatin-d<sub>3sub> ammonium	Reactive Oxygen Species HMG-CoA Reductase (HMGCR) Isotope-Labeled Compounds	Inflammation/Immunology
Simvastatin acid-d₃ (Tenivastatin-d₃) ammonium is deuterium-labeled Simvastatin acid (ammonium) (HY-119695A) .

HY-Y0479

*L-Lactic* acid** 5 Publications Verification (S)-2-Hydroxypropanoic acid	Bacterial Endogenous Metabolite Antibiotic	Infection Cancer
L-Lactic acid is a buildiing block which can be used as a precursor for the production of the bioplastic polymer poly-lactic acid.

HY-Y1313S

3-Nitrobenzoic acid-d4 m-Carboxynitrobenzene-d<sub>4sub>; m-Nitrobenzenecarboxylic acid-d<sub>4sub>; m-Nitrobenzoic acid-d<sub>4sub>	Isotope-Labeled Compounds	Others
3-Nitrobenzoic acid-d₄ is the deuterium labeled 3-Nitrobenzoic acid[1].

HY-N0384S

Homovanillic acid-d3 Vanilacetic acid-d<sub>3sub>	Endogenous Metabolite	Metabolic Disease
Homovanillic acid-d₃ is the deuterium labeled Homovanillic acid. Homovanillic acid is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency.

HY-41417S1

Octanoic acid-d3 Caprylic acid-d<sub>3sub>	Endogenous Metabolite	Metabolic Disease
Octanoic acid-d₃ is the deuterium labeled Octanoic acid. Octanoic acid (Caprylic acid) is an oily liquid with a slightly unpleasant rancid taste and used commercially in the production of esters used in perfumery and also in the manufacture of dyes.

HY-Y0479S3

*L-Lactic* acid-2-13C1**	Bacterial Endogenous Metabolite Antibiotic	Infection
L-Lactic acid-2- ¹³C₁ is the ¹³C-labeled L-Lactic acid. L-Lactic acid is a buildiing block which can be used as a precursor for the production of the bioplastic polymer poly-lactic acid.

HY-158995S

3-Epiglycyrrhetinic acid-d2 3α-Glycyrrhetic acid-d<sub>2sub>	Isotope-Labeled Compounds	Others
3-Epiglycyrrhetinic acid-d2 (3α-Glycyrrhetic acid-d2) is the deuterium-labeled 3-Epiglycyrrhetinic acid. 3-Epiglycyrrhetinic acid is a derivative of glycyrrhetic acid. Glycyrrhetic acid and its derivative are considered to have anti-inflammatory, anti-ulcer, and antiviral activities .

HY-Y0957S

2,5-Difluorobenzoic acid-d3 NSC 190310-d<sub>3sub>	Isotope-Labeled Compounds	Others
2,5-Difluorobenzoic acid-d₃ is the deuterium labeled 2,5-Difluorobenzoic acid[1].

HY-113099

Indolelactic acid 4 Publications Verification Indole-3-Lactic acid	Endogenous Metabolite	Inflammation/Immunology
Indolelactic acid (Indole-3-lactic acid) is a tryptophan (Trp) catabolite in Azotobacter vinelandii cultures. Indolelactic acid has anti-inflammation and potential anti-viral activity ^[3] .

HY-107494S2

4-Oxoretinoic acid-d3 4-Keto retinoic acid-d<sub>3sub>	Isotope-Labeled Compounds	Others
4-Oxoretinoic acid-d₃ is the deuterium labeled 4-Oxoretinoic acid[1].

HY-W004260S2

Arachidic acid-d3 Icosanoic acid-d<sub>3sub>	Isotope-Labeled Compounds Endogenous Metabolite	Others
Arachidic acid-d₃) is the deuterium labeled Arachidic acid. Arachidonic acid (Icosanoic acid), a long-chain fatty acid, is present in all mammalian cells, typically esterified to membrane phospholipids, and is one of the most abundant polyunsaturated fatty acids present in human tissue[1][2].

HY-N7057S1

Nonanoic acid-d3 Pelargonic acid-d<sub>3sub>	Isotope-Labeled Compounds Bacterial	Infection
Nonanoic acid-d₃ is the deuterium labeled Nonanoic acid. Nonanoic acid is a naturally-occurring saturated fatty acid with nine carbon atoms. Nonanoic acid significantly reduces bacterial translocation, enhances antibacterial activity, and remarkably increases the secretion of porcine β-defensins 1 (pBD-1) and pBD-2[1].

HY-141540

Lactyl-CoA	Others	Others
Lactyl-CoA is an acyl-CoA formally condensed from the sulfhydryl group of CoA and the carboxyl group of lactic acid, also known as lactyl-CoA. Lactyl-CoA is essential for the biosynthesis of biodegradable and biocompatible lactic acid-based copolymers .

HY-121883S1

Lignoceric acid-d3 Tetracosanoic acid-d<sub>3sub>	Endogenous Metabolite	Neurological Disease
Lignoceric acid-d₃ is the deuterium labeled Lignoceric acid[1]. Lignoceric acid (Tetracosanoic acid) is a 24-carbon saturated (24:0) fatty acid, which is synthesized in the developing brain. Lignoceric acid is also a by-product of lignin production. Lignoceric acid can be used for Zellweger cerebro‐hepato‐renal syndrome and adrenoleukodystrophy research[2][3].

HY-W091636S

3,3'-Azanediyldipropionic acid-d8 3,3'-Iminodipropionic acid-d<sub>8sub>	Isotope-Labeled Compounds	Others
3,3'-Azanediyldipropionic acid-d₈ is the deuterium labeled 3,3'-Azanediyldipropionic acid[1].

HY-101411S

4-Acetamidobutanoic acid-d3 N-acetyl GABA-d<sub>3sub>	Bacterial GABA Receptor Endogenous Metabolite Isotope-Labeled Compounds	Others
4-Acetamidobutanoic acid-d3 is the deuterated analog of 4-Acetamidobutanoic acid (HY-101411). 4-Acetamidobutanoic acid (N-acetyl GABA), the main metabolite of GABA, exhibits antioxidant and antibacterial activities .

HY-111095S2

*D-(-)-Lactic* acid-13C-1** (R)-2-Hydroxypropionic acid-¹³C-1; D-Lactic acid-¹³C-1	Endogenous Metabolite	Others
D-(-)-Lactic acid- ¹³C-1 is the ¹³C labeled D-(-)-Lactic acid. D-(-)-Lactic acid is a normal intermediate in the fermentation (oxidation, metabolism) of sugar. D-(-)-Lactic acid is identified to be a competitive inhibitor of ProDH (proline dehydrogenase) in plants .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-Y0479

*L-Lactic* acid** 5 Publications Verification (S)-2-Hydroxypropanoic acid	Structural Classification Classification of Application Fields Source classification Endocrine diseases Endogenous metabolite Infection Immune System Disorder Microorganisms Ketones, Aldehydes, Acids Disease markers Nervous System Disorder Disease Research Fields Cardiovascular System Disorder	Bacterial Endogenous Metabolite Antibiotic
L-Lactic acid is a buildiing block which can be used as a precursor for the production of the bioplastic polymer poly-lactic acid.

HY-113099

Indolelactic acid 4 Publications Verification Indole-3-Lactic acid	Structural Classification Human Gut Microbiota Metabolites Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Indolelactic acid (Indole-3-lactic acid) is a tryptophan (Trp) catabolite in Azotobacter vinelandii cultures. Indolelactic acid has anti-inflammation and potential anti-viral activity ^[3] .

HY-111095B

*D-(-)-Lactic* acid sodium** (R)-2-Hydroxypropionic acid sodium	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
D-(-)-Lactic acid ((R)-2-Hydroxypropionic acid ) sodium is an endogenous metabolite.

HY-125833

Alpha-Naphthoflavone 5+ Cited Publications	Flavonoids Flavones Source classification Indigofera heterantha Wall. ex Brand. Plants Compositae Disease Research Fields Cancer	Cytochrome P450 Aryl Hydrocarbon Receptor Apoptosis
Alpha-Naphthoflavone is an orally active flavonoid that is a potent, competitive inhibitor of aromatase< b>aromatase. < b > IC < sub > 50 < / sub > < / b > and < b > K < sub > I < / sub > < / b > value were 0.5 and 0.2 microns. Alpha-Naphthoflavone can inhibit cell proliferation and induce apoptosis ^[3] .

HY-B2227

Lactate 5+ Cited Publications Lactic acid	Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Anti-aging Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Lactate (Lactic acid) is a hydroxycarboxylic acid receptor 1 (HCAR1) activator and an epigenetic modulator inducing lysine residues lactylation. Lactate is a glycolysis end-product, bridging the gap between glycolysis and oxidative phosphorylation. Lactate is an oncometabolite and has immune protective role of lactate in anti-tumor immunity .

HY-B0504S

Creatinine-d3 3 Publications Verification NSC13123-d<sub>3sub>	Classification of Application Fields Metabolic Disease Disease Research Fields	Endogenous Metabolite
Creatinine-d₃ is a deuterium labeled Creatinine. Creatinine is a break-down product of creatine phosphate in muscle[1].

HY-W011474

Geranylgeraniol	Structural Classification Natural Products Microorganisms	NF-κB
Geranylgeraniol is an orally acitve vitamin K₂ sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model ^[3] .

HY-N8139

2-Amino-3-carboxy-1,4-naphthoquinone	Alkaloids Quinones Classification of Application Fields Source classification Rubiaceae Metabolic Disease Plants Naphthalene Quinones Disease Research Fields Rubia cordifolia L.	Others
2-Amino-3-carboxy-1,4-naphthoquinone is the electron transfer mediator. 2-Amino-3-carboxy-1,4-naphthoquinone changes glucose metabolism of the homofermentative lactic acid bacteria .

HY-Y0479R

*L-Lactic* acid (Standard)**	Infection Structural Classification Immune System Disorder Microorganisms Ketones, Aldehydes, Acids Source classification Disease markers Endocrine diseases Nervous System Disorder Endogenous metabolite Cardiovascular System Disorder	Bacterial Endogenous Metabolite Antibiotic
L-Lactic acid (Standard) is the analytical standard of L-Lactic acid. This product is intended for research and analytical applications. L-Lactic acid is a buildiing block which can be used as a precursor for the production of the bioplastic polymer poly-lactic acid.

HY-N11799

Neochilenin 3-O-Methylquercetin 4′-O-glucoside	Structural Classification Flavonoids Source classification Plants Compositae Other Flavonoids	Others
Neochilenin (3-O-Methylquercetin 4 '-O-glucoside) is a glycoside of 3-O-methylquercetin, which can be isolated from the sub-family Cereoideae (Cactaceae). .

HY-P2274

Argifin	Infection Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields	Parasite
Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms, with IC₅₀s of 0.025 μM, 6.4 μM , 1.1 μM and 4.5 μM for SmChiA (Serratia marcescens chitinaese A), SmChiB, Aspergillus fumigatus chitinase B1 and human chitotriosidase, respectively .

HY-N10192

Aculene D	Infection Microorganisms Classification of Application Fields Terpenoids Sesquiterpenes Source classification Disease Research Fields	Endogenous Metabolite Bacterial
Aculene D, a fungal metabolite, shows quorum sensing (QS) inhibitory activity against Chromobacterium violaceum CV026, and could significantly reduce violacein production in N-hexanoyl-l-homoserine lactone (C6-HSL) induced C. violaceum CV026 cultures at sub-inhibitory concentrations .

HY-W011474R

Geranylgeraniol (Standard)	Structural Classification Natural Products Microorganisms	NF-κB
Geranylgeraniol (Standard) is the analytical standard of Geranylgeraniol. This product is intended for research and analytical applications. Geranylgeraniol is an orally acitve vitamin K2 sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model ^[3][4].

HY-N0662

Amentoflavone Maximum Cited Publications 9 Publications Verification Didemethyl-ginkgetin	Structural Classification Flavonoids Classification of Application Fields Source classification Phenols Polyphenols Selaginellaceae Plants Biflavones Selaginella tamariscina (P. Beauv.) Spring Disease Research Fields Cancer	Reactive Oxygen Species Apoptosis Bacterial Fungal RSV GABA Receptor
Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active GABA(A) negative modulator. Amentoflavone also shows anti-inflammatory, antioxidative, anti-viral, anti-tumor, anti-radiation, anti-fungal, antibacterial activity. Amentoflavone induces apoptosis and cell cycle arrest at sub-G1 phase ^[3] .

HY-113133

Kojibiose	Microorganisms Source classification	Glucosidase
Kojibiose, an orally active prebiotic disaccharide, can specifically inhibit the activity of α-glucosidase I. kojibiose is a proliferation factor for Bifidobacterium, lactic acid bacteria, and eubacteria. kojibiose is a low-calorie sweetener capable of increasing the absorption of iron. Kojibiose exhibits antitoxic activity. Kojibiose reduces hepatic expression of inflammatory markers in vivo .

HY-N0662R

Amentoflavone (Standard)	Structural Classification Flavonoids Source classification Phenols Polyphenols Selaginellaceae Plants Biflavones Selaginella tamariscina (P. Beauv.) Spring	Reactive Oxygen Species Apoptosis Bacterial Fungal RSV GABA Receptor
Amentoflavone (Standard) is the analytical standard of Amentoflavone. This product is intended for research and analytical applications. Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active GABA(A) negative modulator. Amentoflavone also shows anti-inflammatory, antioxidative, anti-viral, anti-tumor, anti-radiation, anti-fungal, antibacterial activity. Amentoflavone induces apoptosis and cell cycle arrest at sub-G1 phase ^[3] .

HY-W005288

4-Vinylphenol	Monophenols Microorganisms Classification of Application Fields Source classification Rubiaceae Phenols Plants Endogenous metabolite Disease Research Fields Cancer Hedyotis diffusa Willd.	Apoptosis Endogenous Metabolite
4-Vinylphenol is found in the medicinal herb Hedyotis diffusa Willd, wild rice and is also the metabolite of p-coumaric and ferulic acid by lactic acid bacteria in wine. 4-Vinylphenol induces apoptosis and inhibits blood vessels formation and suppresses invasive breast tumor growth in vivo .

HY-N0216BS

Benzoic-3,5 Acid-d2	Classification of Application Fields	Isotope-Labeled Compounds
Benzoic-3,5 Acid-d₂ is the deuterium labeled Benzoic-3,5 Acid[1].

HY-B2227R

Lactate (Standard)	Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Endogenous Metabolite
Lactate (Standard) is the analytical standard of Lactate. This product is intended for research and analytical applications. Lactate (Lactic acid) is a hydroxycarboxylic acid receptor 1 (HCAR1) activator and an epigenetic modulator inducing lysine residues lactylation. Lactate is a glycolysis end-product, bridging the gap between glycolysis and oxidative phosphorylation. Lactate is an oncometabolite and has immune protective role of lactate in anti-tumor immunity .

HY-Y0335

1,3-Dihydroxyacetone Dihydroxyacetone	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
1,3-Dihydroxyacetone (DHA), the main active ingredient in sunless tanning skin-care preparations and an important precursor for the synthesis of various fine chemicals, is produced on an industrial scale by microbial fermentation of glycerol (HY-B1659) in Gluconobacter oxydans. 1,3-Dihydroxyacetone is also used for synthesis of new biodegradable polymers by combining with lactic acid (HY-B2227) .

HY-Y0335R

1,3-Dihydroxyacetone (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Endogenous Metabolite
1,3-Dihydroxyacetone (Standard) is the analytical standard of 1,3-Dihydroxyacetone. This product is intended for research and analytical applications. 1,3-Dihydroxyacetone (DHA), the main active ingredient in sunless tanning skin-care preparations and an important precursor for the synthesis of various fine chemicals, is produced on an industrial scale by microbial fermentation of glycerol (HY-B1659) in Gluconobacter oxydans. 1,3-Dihydroxyacetone is also used for synthesis of new biodegradable polymers by combining with lactic acid (HY-B2227) .

Cat. No.	Product Name	Chemical Structure

HY-B2227BS1

Lactate-d3 sodium
Lactate-d₃ (sodium) is the deuterium labeled Lactate sodium. Lactate sodium is the product of glycogenolysis and glycolysis. Lactate sodium functions in a variety of biochemical processes[1][2].

HY-Y0479AS

*L-Lactic* acid-13C3 sodium**
L-Lactic acid- ¹³C₃ (sodium) is the ¹³C labeled L-Lactic acid. L-Lactic acid- ¹³C₃ sodium can be used for lactate metabolism research[1].

HY-B0302AS

Etidronic acid-d3 disodium
Etidronic acid-d₃ (disodium) is the deuterium labeled Etidronic acid disodium[1].

HY-103395S

Methylmalonic acid-d3
Methylmalonic acid-d₃ is the deuterium labeled Methylmalonic acid. Methylmalonic acid (Methylmalonate) is an indicator of Vitamin B-12 deficiency in cancer[1][2].

HY-18569S

3-Indoleacetic acid-d5 1 Publications Verification
3-Indoleacetic acid-d₅ is the deuterium labeled 3-Indoleacetic acid. 3-Indoleacetic acid-d₅ can be used as internal standard for assay of IAA releases by alkaline hydrolysis of ester and amide conjugates[1].

HY-15027S

5-Aminosalicylic Acid-d3 hydrochloride
5-Aminosalicylic Acid-d₃ (hydrochloride) is the deuterium labeled 5-Aminosalicylic Acid. 5-Aminosalicylic acid (Mesalamine) hydrochloride acts as a specific PPARγ agonist and also inhibits p21-activated kinase 1 (PAK1) and NF-κB.

HY-13777S1

Zoledronic acid-d3
Zoledronic acid-d3 is the deuterium labeled Zoledronic acid .

HY-N0156S

Oleanolic acid-d3
Oleanolic acid-d₃ is the deuterium labeled Oleanolic Acid[1]. Oleanolic acid (Caryophyllin) is a natural compound from plants with anti-tumor activities[2].

HY-75087S

(R)-Pyrrolidine-2-carboxylic acid-d3
(R)-Pyrrolidine-2-carboxylic acid-d₃ is the deuterium labeled (R)-pyrrolidine-2-carboxylic acid. (R)-pyrrolidine-2-carboxylic acid is an endogenous metabolite.

HY-W154267S

3-Aminoisobutyric acid-d3 hydrochloride
3-Aminoisobutyric acid-d₃ (hydrochloride) is the deuterium labeled DL-Histidine[1].

HY-W004282S1

Undecanoic acid-d3
Undecanoic acid-d₃ is the deuterium labeled Undecanoic acid. Undecanoic acid (Undecanoate) is a monocarboxylic acid with antimycotic property, which inhibits the production of exocellular keratinase, lipase and the biosynthesis of several phospholipids in T. rubrum[1].

HY-I0746S

3-Aminobenzoic acid-d4
3-Aminobenzoic acid-d₄ is the deuterium labeled 3-Aminobenzoic acid[1].

HY-15027S1

5-Aminosalicylic acid-d3
5-Aminosalicylic acid-d₃ is the deuterium labeled 5-Aminosalicylic Acid. 5-Aminosalicylic acid (Mesalamine) acts as a specific PPARγ agonist and also inhibits p21-activated kinase 1 (PAK1) and NF-κB[1][2][3][4].

HY-113099S

Indolelactic acid-d5
Indolelactic acid-d₅ is the deuterium labeled Indolelactic acid. Indolelactic acid is a tryptophan (Trp) catabolite in Azotobacter vinelandii cultures.

HY-13318S

Oseltamivir acid-d3 Maximum Cited Publications 56 Publications Verification
Oseltamivir acid-d₃ is a deuterium labeled Oseltamivir acid. Oseltamivir acid, the active metabolite of Oseltamivir phosphate, is an orally bioavailable, potent and selective inhibitor of influenza virus neuraminidase (IC50=2 nM) with activity against both influenza A and B viruses[1][2].

HY-Y1311S

Malic acid-d3
Malic acid-d₃ is the deuterium labeled Malic acid. Malic acid (Hydroxybutanedioic acid) is a dicarboxylic acid that is naturally found in fruits such as apples and pears. It plays a role in many sour or tart foods[1][2].

HY-Y0084S

3,4,5-Trimethoxybenzoic acid-d3
3,4,5-Trimethoxybenzoic acid-d₃ is the deuterium labeled 3,4,5-Trimethoxybenzoic acid[1]. 3,4,5-Trimethoxybenzoic acid (Eudesmic acid;Trimethylgallic Acid) is a benzoic acid derivative. A building block in medicine and organic synthesis.

HY-158995S1

3-Epiglycyrrhetinic acid-d3
3-Epiglycyrrhetinic acid-d3 (3α-Glycyrrhetic acid-d3) is the deuterium-labeled 3-Epiglycyrrhetinic acid. 3-Epiglycyrrhetinic acid is a derivative of glycyrrhetic acid. Glycyrrhetic acid and its derivative are considered to have anti-inflammatory, anti-ulcer, and antiviral activities .

HY-Y1069S

(S)-Malic acid-d3
(S)-Malic acid-d₃ is the deuterium labeled (S)-Malic acid. (S)-Malic acid ((S)-2-Hydroxysuccinic acid) is a dicarboxylic acid in naturally occurring form, contributes to the pleasantly sour taste of fruits and is used as a food additive[1][2].

HY-10844S1

Pretomanid-d5
Pretomanid-d₅ is deuterated labeled Pretomanid (HY-10844). Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 μg/mL.

HY-18569S1

3-Indoleacetic acid-d4
3-Indoleacetic acid-d₄ (Indole-3-acetic acid-d₄; 3-IAA-d₄)is the deuterium labeled3-Indoleacetic acid(HY-18569) . 3-Indoleacetic acid (Indole-3-acetic acid) is the most common natural plant growth hormone of the auxin class. It can be added to cell culture medium to induce plant cell elongation and division .

HY-B0421S

Mycophenolic acid-d3
Mycophenolic acid-d₃ is deuterium labeled Mycophenolic acid, which is an an immunosuppresant agent and has potent anti-proliferative activity.

HY-113335S

Trihydroxycholestanoic acid-d3
Trihydroxycholestanoic acid-d₃ is the deuterium labeled Trihydroxycholestanoic acid[1].

HY-B1053S

Iotalamic acid-d3
Iotalamic acid-d₃ is the deuterium labeled Iotalamic acid[1].

HY-15027S3

5-Aminosalicylic acid-d3 disodium
5-Aminosalicylic acid-d₃ disodium is deuterated labeled 5-Aminosalicylic Acid (HY-15027). 5-Aminosalicylic acid (Mesalamine) acts as a specific PPARγ agonist and also inhibits p21-activated kinase 1 (PAK1) and NF-κB.5-Aminosalicylic acid can inhibit the activity of osteopontin (OPN).

HY-Y1088S3

Hydrocinnamic acid-d5
Hydrocinnamic acid-d₅ is the deuterium labeled Hydrocinnamic acid[1]. Hydrocinnamic acid is the major rhizospheric compound with known growth regulatory activities[2].

HY-Y1088S2

Hydrocinnamic acid-d9
Hydrocinnamic acid-d₉ is the deuterium labeled Hydrocinnamic acid[1]. Hydrocinnamic acid is the major rhizospheric compound with known growth regulatory activitie[2]s.

HY-113371AS

2-Methylcitric acid-d3 trisodium
2-Methylcitric acid-d₃ (Methylcitric acid-d₃) trisodium is deuterium-labeled 2-Methylcitric acid (trisodium) (HY-113371A) .

HY-N0384S4

Homovanillic acid-d3-1
Homovanillic acid-d3-1 (Vanilacetic acid-d3-1) is deuterated labeled Homovanillic acid (HY-N0384). Homovanillic acid is a dopamine metabolite associated with aromatic amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and adiponectin reductase deficiency .

HY-18569S3

3-Indoleacetic acid-d7
3-Indoleacetic acid-d₇ is the deuterium labeled 3-Indoleacetic acid[1]. 3-Indoleacetic acid (Indole-3-acetic acid) is the most common natural plant growth hormone of the auxin class. It can be added to cell culture medium to induce plant cell elongation and division.

HY-119695AS2

Simvastatin acid-d3 ammonium
Simvastatin acid-d₃ (Tenivastatin-d₃) ammonium is deuterium-labeled Simvastatin acid (ammonium) (HY-119695A) .

HY-Y1313S

3-Nitrobenzoic acid-d4
3-Nitrobenzoic acid-d₄ is the deuterium labeled 3-Nitrobenzoic acid[1].

HY-N0384S

Homovanillic acid-d3
Homovanillic acid-d₃ is the deuterium labeled Homovanillic acid. Homovanillic acid is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency.

HY-41417S1

Octanoic acid-d3
Octanoic acid-d₃ is the deuterium labeled Octanoic acid. Octanoic acid (Caprylic acid) is an oily liquid with a slightly unpleasant rancid taste and used commercially in the production of esters used in perfumery and also in the manufacture of dyes.

HY-Y0479S3

*L-Lactic* acid-2-13C1**
L-Lactic acid-2- ¹³C₁ is the ¹³C-labeled L-Lactic acid. L-Lactic acid is a buildiing block which can be used as a precursor for the production of the bioplastic polymer poly-lactic acid.

HY-158995S

3-Epiglycyrrhetinic acid-d2
3-Epiglycyrrhetinic acid-d2 (3α-Glycyrrhetic acid-d2) is the deuterium-labeled 3-Epiglycyrrhetinic acid. 3-Epiglycyrrhetinic acid is a derivative of glycyrrhetic acid. Glycyrrhetic acid and its derivative are considered to have anti-inflammatory, anti-ulcer, and antiviral activities .

HY-Y0957S

2,5-Difluorobenzoic acid-d3
2,5-Difluorobenzoic acid-d₃ is the deuterium labeled 2,5-Difluorobenzoic acid[1].

HY-107494S2

4-Oxoretinoic acid-d3
4-Oxoretinoic acid-d₃ is the deuterium labeled 4-Oxoretinoic acid[1].

HY-W004260S2

Arachidic acid-d3
Arachidic acid-d₃) is the deuterium labeled Arachidic acid. Arachidonic acid (Icosanoic acid), a long-chain fatty acid, is present in all mammalian cells, typically esterified to membrane phospholipids, and is one of the most abundant polyunsaturated fatty acids present in human tissue[1][2].

HY-N7057S1

Nonanoic acid-d3
Nonanoic acid-d₃ is the deuterium labeled Nonanoic acid. Nonanoic acid is a naturally-occurring saturated fatty acid with nine carbon atoms. Nonanoic acid significantly reduces bacterial translocation, enhances antibacterial activity, and remarkably increases the secretion of porcine β-defensins 1 (pBD-1) and pBD-2[1].

HY-121883S1

Lignoceric acid-d3
Lignoceric acid-d₃ is the deuterium labeled Lignoceric acid[1]. Lignoceric acid (Tetracosanoic acid) is a 24-carbon saturated (24:0) fatty acid, which is synthesized in the developing brain. Lignoceric acid is also a by-product of lignin production. Lignoceric acid can be used for Zellweger cerebro‐hepato‐renal syndrome and adrenoleukodystrophy research[2][3].

HY-W091636S

3,3'-Azanediyldipropionic acid-d8
3,3'-Azanediyldipropionic acid-d₈ is the deuterium labeled 3,3'-Azanediyldipropionic acid[1].

HY-101411S

4-Acetamidobutanoic acid-d3
4-Acetamidobutanoic acid-d3 is the deuterated analog of 4-Acetamidobutanoic acid (HY-101411). 4-Acetamidobutanoic acid (N-acetyl GABA), the main metabolite of GABA, exhibits antioxidant and antibacterial activities .

HY-111095S2

*D-(-)-Lactic* acid-13C-1**
D-(-)-Lactic acid- ¹³C-1 is the ¹³C labeled D-(-)-Lactic acid. D-(-)-Lactic acid is a normal intermediate in the fermentation (oxidation, metabolism) of sugar. D-(-)-Lactic acid is identified to be a competitive inhibitor of ProDH (proline dehydrogenase) in plants .

HY-76547S2

p-Toluic acid-d3
p-Toluic acid-d3 is the deuterium labeled p-Toluic acid[1]. p-Toluic acid (4-Methylbenzoic acid) is a substituted benzoic acid and can be used as an intermediate for the synthesis of para-aminomethylbenzoic acid (PAMBA), p-tolunitrile, etc.

HY-W018728S

3,5-Dimethylbenzoic acid-d9
3,5-Dimethylbenzoic acid-d₉ is the deuterium labeled 3,5-Dimethylbenzoic acid[1].

HY-B1689AS

Methantheline-d3 bromide
Methantheline-d₃ (bromide) is the deuterium labeled Methantheline bromide[1].

HY-78985S

Benzene-1,3,5-tricarboxylic acid-d3
Benzene-1,3,5-tricarboxylic acid-d₃ is the deuterium labeled Benzene-1,3,5-tricarboxylic acid[1].

HY-113371S

2-Methylcitric acid-d3

2-Methylcitric acid-d₃ is the deuterium labeled 2-Methylcitric acid. 2-Methylcitric acid (Methylcitric acid) is an endogenous metabolite in the 2-methylcitric acid cycle. 2-Methylcitric acid accumulates in methylmalonic and propionic acidemias and acts as a marker metabolite. 2-Methylcitric acid markedly inhibits ADP-stimulated and uncoupled respiration in mitochondria supported by glutamate[1].

HY-W014839S1

Cyclamic acid-d4 sodium
Cyclamic acid-d4 (sodium) is the deuterium labeled Cyclamic acid (sodium) .

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Lactic acid-d<sub>3</sub>

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