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DMABA-d<sub>4</sub> NHS ester

" in MedChemExpress (MCE) Product Catalog:

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Click Chemistry:	ADC Synthesis (46) TCO (20) Labeling and Fluorescence Imaging (1) DBCO (28) PROTAC Synthesis (65) BCN (11) Azide (44) Tetrazine (21) Alkynes (32)
Oligonucleotides:	Pegylated Lipids (8) Aptamers (2) Pre-designed siRNA Sets (2) Phospholipids (4) Polymers (6) siRNAs (2) Sweetening Agents (1)

3653

Inhibitors & Agonists

133

Fluorescent Dye

Biochemical Assay Reagents

Peptides

MCE Kits

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

2900

Isotope-Labeled Compounds

Antibodies

156

Click Chemistry

Oligonucleotides

Targets Recommended: CETP P-glycoprotein

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-118431

DMABA NHS ester	Others	Others
DMABA NHS ester can chemically react with the primary amine groups of the major phospholipid component of the cell membrane, Phosphatidylethanolamine (PE). Through precursor ion scanning, all PE subclasses labeled with DMABA can be detected. DMABA NHS ester can be used in combination with isotope-labeled compounds such as DMABA-d6 NHS ester, DMABA-d10 NHS ester, and DMABA-d4 NHS ester to observe changes in the distribution of PE lipids and the formation of novel PE lipid products .

HY-118431S2

DMABA-d6 NHS ester	Isotope-Labeled Compounds	Others
DMABA-d₆ NHS ester is the deuterium labeled DMABA NHS ester[1].

HY-118431S3

DMABA-d10 NHS ester	Isotope-Labeled Compounds	Others
DMABA-d₁₀ NHS ester is the deuterium labeled DMABA NHS ester[1].

HY-118431S

DMABA-d4 NHS ester	Isotope-Labeled Compounds	Others
DMABA-d₄ NHS ester is the deuterium labeled DMABA NHS ester[1].

HY-D1730

*AF488 NHS* ester**	Fluorescent Dye	Others
AF488 NHS ester is an amine specific fluorescence probe (Em=525 nm). AF488 NHS ester reacts with sulfhydryl groups and amines in aqueous and biological samples then change their chemical structure and fluorescence properties after derivatization .

HY-D2291

*BODIPY TMR NHS* ester**	Fluorescent Dye	Others
BODIPY TMR NHS ester is bright, orange fluorescent dye with Ex/Em of 544/570 nm. The NHS ester (or succinimidyl ester) of BODIPY TMR NHS ester is a popular tool for conjugating the dye to a protein or antibody. NHS esters can be used to label the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules .

HY-RS13999

SUB1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SUB1 Human Pre-designed siRNA Set A contains three designed siRNAs for SUB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SUB1 Human Pre-designed siRNA Set A SUB1 Human Pre-designed siRNA Set A

HY-146227

DNA topoisomerase II inhibitor 1	Topoisomerase Apoptosis	Cancer
DNA topoisomerase II inhibitor 1 (compound 8ed) is a potent DNA topoisomerase II inhibitor. DNA topoisomerase II inhibitor 1 shows anti-proliferative activity. DNA topoisomerase II inhibitor 1 induces apoptosis and cell cycle arrest at sub G1 phase .

HY-141166A

*(S,E)-TCO2-PEG3-NHS* ester**	Biochemical Assay Reagents	Cancer
(S,E)-TCO2-PEG3-NHS ester is NH₂ reactive, and can be used in chemical synthesis. (S,E)-TCO2-PEG3-NHS ester contains TCO groups, which can undergo specific "click" reactions with tetrazine groups .

HY-D2290

*Demethoxy-BODIPY TMR NHS* ester**	Fluorescent Dye	Others
Demethoxy-BODIPY TMR NHS ester is an amine-reactive fluorescent probe, and can be used for the labeling of proteins, peptides, and other molecules .

HY-D1568

*Sulfo-Cy7.5 NHS* ester**	Fluorescent Dye	Others
Sulfo-Cy7.5 NHS ester is a near infrared water soluble hydrophilic dye, also is an NHS ester for the modification of amine groups. Sulfo-Cy7.5 NHS ester contains a trimeth ylene bridge and has a linker arm for its attachment to proteins, peptides, and other molecules. Sulfo-Cy7.5 NHS ester can be used for the research of NIR imaging applications .

HY-D2178

*AF 568 NHS* ester**	Fluorescent Dye	Others
AF 568 NHS ester is a derivative of the orange fluorescent dye AF 568. AF 568 NHS ester is widely used in cell dyes, biological dyes, biomolecules and particle fluorescent labeling. AF 568 exhibits maximum absorption wavelength of 579 nm and the maximum emission wavelength of 603 nm .

HY-D1567

*Cy7.5 NHS* ester**	Fluorescent Dye	Others
Cy7.5 NHS ester is a fluorescent dye. Cy7.5 NHS ester can be conjugated to mPEG-b-PDPA to form a mPEG-b-PDPA-Cy7.5 fluorescent copolymer. Cy7.5 NHS ester can be used for fluorescent imaging study .

HY-10844S1

Pretomanid-d5 PA-824-d<sub>5sub>; (S)-PA 824-d<sub>5sub>	Antibiotic Bacterial Isotope-Labeled Compounds	Infection Cancer
Pretomanid-d₅ is deuterated labeled Pretomanid (HY-10844). Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 μg/mL.

HY-160773

*DBCO-PEG6-NHS* ester**	Biochemical Assay Reagents	Others
DBCO-PEG6-NHS ester is a click chemistry PEG reagent containing an NHS ester that reacts specifically with primary amines, such as side chains of lysine residues or aminosilane-coated surfaces, under neutral or slightly alkaline conditions. , efficient reaction to form covalent bonds. DBCO-PEG6-NHS ester also contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .

HY-164165

*Paclitaxel-2′-succinate NHS* ester**	Others	Cancer
Paclitaxel-2′-succinate NHS ester is a paclitaxel derivative with a succinic acid linker, in which the carboxyl group is activated by the NHS ester. The NHS ester group is highly reactive toward amino or hydroxyl groups and can be used to conjugate with other molecules such as peptides, proteins, antibodies, enzymes or polymers. Paclitaxel-2′-succinate NHS ester can be used in the development of nanomedicines and in the study of cancer therapy .

HY-41680S

4-Aminobenzonitrile-d4 4-Aminobenzonitrile-d<sub>4sub>; 4-Cyanoaniline-d<sub>4sub>; 4-Cyanobenzenamine-d<sub>4sub>	Isotope-Labeled Compounds	Others
4-Aminobenzonitrile-d₄ is the deuterium labeled 4-Aminobenzonitrile[1].

HY-66005S

Acetaminophen-d4 Paracetamol-d<sub>4sub>; 4-Acetamidophenol-d<sub>4sub>; 4'-Hydroxyacetanilide-d<sub>4sub>	COX Histone Acetyltransferase Endogenous Metabolite	Inflammation/Immunology
Acetaminophen-d₄ is the deuterium labeled Acetaminophen. Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM; is a widely used antipyretic and analgesic agent[1][2][3]. Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor[4].

HY-Y1042S

4-Cyanophenol-d4 4-Hydroxybenzonitrile-d<sub>4sub>; 4-Hydroxycyanobenzene-d<sub>4sub>; NSC 400524-d<sub>4sub>	Isotope-Labeled Compounds	Others
4-Cyanophenol-d₄ is the deuterium labeled 4-Cyanophenol[1].

HY-D1119C

*AF647-NHS* ester triTEA**	Fluorescent Dye	Others
AF647-NHS ester is an analogue of Alexa Fluor 647 (AF647), which has excitation wavelength (λ_ex) of 635 nm (conventional fluorescence detection)/620 nm (instantaneous detection) .

HY-17413S2

Zidovudine-d4 Azidothymidine-d<sub>4sub>; AZT-d<sub>4sub>; ZDV-d<sub>4sub>	CRISPR/Cas9 HIV Isotope-Labeled Compounds	Infection Cancer
Zidovudine-d₄ is deuterated labeled Zidovudine (HY-17413). Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection. Zidovudine increases CRISPR/Cas9-mediated editing frequency.

HY-B1008S

4-Aminobenzoic acid-d4 PABA-d<sub>4sub>; Vitamin Bx-d<sub>4sub>; Vitamin H1-d<sub>4sub>; p-Aminobenzoic acid-d<sub>4sub>	Isotope-Labeled Compounds Endogenous Metabolite	Others
4-Aminobenzoic acid-d₄ is the deuterium labeled 4-Aminobenzoic acid. 4-Aminobenzoic acid is an intermediate in the synthesis of folate by bacteria, plants, and fungi.

HY-N0006S1

Demethoxycurcumin-d4 Curcumin II-d<sub>4sub>; Desmethoxycurcumin-d<sub>4sub>; Monodemethoxycurcumin-d<sub>4sub>	Apoptosis Autophagy Bacterial	Cancer
Demethoxycurcumin-d₄ is the deuterium labeled Demethoxycurcumin. Demethoxycurcumin (Curcumin II) is a major active curcuminoid; possess anti-inflammatory properties[1].

HY-B0329S

Isoniazid-d4 INH-d<sub>4sub>; Isonicotinic acid hydrazide-d<sub>4sub>; Isonicotinic hydrazide-d<sub>4sub>	Bacterial Autophagy Mitophagy Antibiotic	Infection
Isoniazid-d₄ is the deuterium labeled Isoniazid. Isoniazid (INH) is a proagent and must be activated by a bacterial catalase-peroxidase enzyme KatG. Isoniazid is bactericidal to rapidly dividing mycobacteria and has anti-tuberculostatic activity[1][2][3][4].

HY-100048S

Acetylisoniazid-d4 Acetylisoniazide-d<sub>4sub>; N-Monoacetylisoniazid-d<sub>4sub>; NSC 36084-d<sub>4sub>	Isotope-Labeled Compounds	Others
Acetylisoniazid-d₄ is the deuterium labeled Acetylisoniazid[1].

HY-118861S

Enclomiphene-d4 hydrochloride (E)-Clomiphene-d<sub>4sub> hydrochloride; trans-Clomiphene-d<sub>4sub> hydrochloride; Enclomifene-d<sub>4sub> hydrochloride	Isotope-Labeled Compounds Estrogen Receptor/ERR	Inflammation/Immunology
Enclomiphene-d₄ (hydrochloride) is a deuterium labeled Enclomiphene. Enclomiphene-d₄ (hydrochloride) is a potent and orally active oestrogen receptor antagonist, with antioestrogenic property[1].

HY-109015S

Tucidinostat-d4 Chidamide-d<sub>4sub>; HBI-8000-d<sub>4sub>; CS 055-d<sub>4sub>	Isotope-Labeled Compounds HDAC	Cancer
Tucidinostat-d₄ is the deuterium labeled Tucidinostat. Tucidinostat is a potent and orally bioavailable HDAC enzymes class I (HDAC1/2/3) and class IIb (HDAC10) inhibitor, with IC50s of 95, 160, 67 and 78 nM, respectively[1].

HY-19696AS

Tauroursodeoxycholate-d4 sodium Tauroursodeoxycholic acid-d<sub>4sub> sodium; TUDCA-d<sub>4sub> sodium; UR 906-d<sub>4sub> sodium	Isotope-Labeled Compounds ERK Caspase Apoptosis Endogenous Metabolite	Cancer
Tauroursodeoxycholate-d₄ (sodium) is the deuterium labeled Tauroursodeoxycholate sodium. Tauroursodeoxycholate (Tauroursodeoxycholic acid; TUDCA) sodium is an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12. Tauroursodeoxycholate also inhibits ERK.

HY-19696S1

Tauroursodeoxycholate-d4 Tauroursodeoxycholic acid-d<sub>4sub>; TUDCA-d<sub>4sub>; UR 906-d<sub>4sub>	Isotope-Labeled Compounds ERK Caspase Endogenous Metabolite Apoptosis	Cancer
Tauroursodeoxycholate-d₄ is deuterium labeled Tauroursodeoxycholate. Tauroursodeoxycholate (Tauroursodeoxycholic acid) is an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12. Tauroursodeoxycholate also inhibits ERK.

HY-B0389S24

D-Glucose-d4 Glucose-d<sub>4sub>; D-(+)-Glucose-d<sub>4sub>; Dextrose-d<sub>4sub>	Endogenous Metabolite	Metabolic Disease Cancer
D-Glucose-d₄ is the deuterium labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molec

HY-B0696AS

Tiagabine-d4 hydrochloride NO050328-dd<sub>4sub> hydrochloride; NO328-d<sub>4sub> hydrochloride; TGB-d<sub>4sub> hydrochloride	GABA Receptor Isotope-Labeled Compounds	Neurological Disease
Tiagabine-d₄ hydrochloride is deuterated labeled Tiagabine hydrochloride (HY-B0696A). Tiagabine hydrochloride is a potent and selective GABA reuptake inhibitor, used as an anticonvulsant agent, with IC₅₀s of 67, 446 and 182 nM for [ ³H]GABA uptake in Synaptosomes, Neurons and Glia, respectively .

HY-13273S

Ostarine-d4 MK-2866-d<sub>4sub>; GTX-024-d<sub>4sub>; Enobosarm-d<sub>4sub>	Isotope-Labeled Compounds Androgen Receptor	Cancer
Ostarine-d4 is a deuterated labeled Ostarine .

HY-145090

*DBCO-N-bis(PEG4-NHS* ester)**	PROTAC Linkers ADC Linker	Others
DBCO-N-bis(PEG4-NHS ester) is a PEG linker which contains two PEG4-NHS ester and a DBCO group. DBCO-N-bis(PEG4-NHS ester) is useful for protein modification or labeling. DBCO-N-bis(PEG4-NHS ester) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-D1352

*Sulfo-Cyanine7 NHS* ester potassium**	Fluorescent Dye	Others
Sulfo-Cyanine7 NHS ester potassium is an amine-reactive succinimide ester. Sulfo-Cyanine7 NHS ester reagent allows to prepare sulfo-Cyanine7-labeled biomolecules, such as proteins, with ease. Dye labeled molecules can be subsequently used for various research and agent design related experiments.

HY-34498S

4-Chloro-2-methylphenol-d4 4-Chloro-o-cresol-d<sub>4sub>; 4-Chlorocresol-d<sub>4sub>; 5-Chloro-2-hydroxytoluene-d<sub>4sub>	Isotope-Labeled Compounds	Others
4-Chloro-2-methylphenol-d₄ is the deuterium labeled 4-Chloro-2-methylphenol[1].

HY-10581AS1

Gatifloxacin-d4 hydrochloride AM-1155-d<sub>4sub> hydrochloride; BMS-206584-d<sub>4sub> hydrochloride; PD135432-d<sub>4sub> hydrochloride	Antibiotic Bacterial Topoisomerase Isotope-Labeled Compounds	Infection
Gatifloxacin-d₄ (AM-1155-d₄; BMS-206584-d₄; PD135432-d₄) hydrochloride is deuterium-labeled Gatifloxacin (hydrochloride) (HY-10581A) .

HY-107542S

Oleoylethanolamide-d4 N-Oleoylethanolamide-d<sub>4sub>; Oleamide MEA-d<sub>4sub>; Oleic acid monoethanolamide-d<sub>4sub>	Isotope-Labeled Compounds Endogenous Metabolite PPAR	Cardiovascular Disease Metabolic Disease
Oleoylethanolamide-d₄ is the deuterium labeled Oleoylethanolamide. Oleoylethanolamide is a high affinity endogenous PPAR-α agonist, which plays an important role in the treatment of obesity and arteriosclerosis.

HY-B0017S

Telbivudine-d4 Epavudine-d<sub>4sub>; L-Thymidine-d<sub>4sub>; NV 02B-d<sub>4sub>	Isotope-Labeled Compounds HBV	Infection
Telbivudine-d₄ is deuterium labeled Telbivudine. Telbivudine (Epavudine), an orally active thymidine nucleoside analog, is a potent antiviral inhibitor of hepatitis B virus (HBV) replication[1].

HY-B0579S

Cyclosporin A-d4 Cyclosporine A-d<sub>4sub>; Ciclosporin A-d<sub>4sub>; CsA-d<sub>4sub>	Antibiotic Complement System Phosphatase	Inflammation/Immunology Cancer
Cyclosporin A-d₄ is the deuterium labeled Cyclosporin A. Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of calcineurin with an IC50 of 5 nM. Cyclosporin A also inhibits CD11a/CD18 ad

HY-N5034S

Phosphorylethanolamine-d4 Monoaminoethyl phosphate-d<sub>4sub>; NSC 254167-d<sub>4sub>; O-Phosphoethanolamine-d<sub>4sub>	Isotope-Labeled Compounds	Metabolic Disease
Phosphorylethanolamine-d₄ (Monoaminoethyl phosphate-d₄; NSC 254167-d₄) is a deuterium labeled Phosphorylethanolamine (HY-N5034). Phosphorylethanolamine is an endogenous metabolite.

HY-16582AS

Sonidegib-d4 Erismodegib-d<sub>4sub>; LDE225-d<sub>4sub>; NVP-LDE225-d<sub>4sub>	Isotope-Labeled Compounds	Others
Sonidegib-d4 is a isotope of Sonidegib. Sonidegib is a potent and selective Smo antagonist with IC₅₀ of 1.3 nM and 2.5 nM for mouse and human Smo in binding assay, respectively .

HY-W700069

Gatifloxacin-d4 AM-1155-d<sub>4sub>; BMS-206584-d<sub>4sub>; PD135432-d<sub>4sub>	Isotope-Labeled Compounds	Others
Gatifloxacin-d4 is the deuterium labeled Gatifloxacin .

HY-78004S1

1,2-Diphenylethane-d4 Dibenzil-d<sub>4sub>; s-Diphenylethane-d<sub>4sub>; Bibenzyl-d<sub>4sub>	Isotope-Labeled Compounds	Others
1,2-Diphenylethane-d4 (Dibenzil-d4; s-Diphenylethane-d4; Bibenzyl-d4) is the deuterium labeled Bibenzyl (HY-78004) .

HY-17422S1

Acyclovir-d4 Aciclovir-d<sub>4sub>; Acycloguanosine-d<sub>4sub>	Isotope-Labeled Compounds HSV Bacterial Apoptosis Antibiotic	Infection Cancer
Acyclovir-d₄ is the deuterium labeled Acyclovir. Acyclovir (Aciclovir) is a guanosine analogue and an orally active antiviral agent. Acyclovir inhibits HSV-1 (IC50 of 0.85 μM), HSV-2 (IC50 of 0.86 μM) and varicella-zoster virus. Acyclovir can be phosphorylated by viral thymidine kinase (TK), and Acyclovir triphosphate interferes with viral DNA polymerization through competitive inhibition with guanosine triphosphate and obligatory chain termination[1][2][3]. Acyclovir prevents bacterial infections during induction therapy for acute leukaemia[4].

HY-B0548AS1

Hydroxyzine-d4' dihydrochloride Vistaril-d<sub>4sub>' dihydrochloride; Atarax-dd<sub>4sub>' dihydrochloride	Histamine Receptor	Inflammation/Immunology Endocrinology
Hydroxyzine-d₄ (dihydrochloride) is the deuterium labeled Hydroxyzine dihydrochloride. Hydroxyzine dihydrochloride, a benzodiazepine antihistamine agent, acts as a orally active histamine H1-receptor and serotonin antagonist. Hydroxyzine dihydrochloride has anxiolytic effect and can be used forthe research of generalised anxiety disorder[1][2].

HY-B0035S

Sulfamethazine-d4 Sulfadimidine-d<sub>4sub>; Sulfadimerazine-d<sub>4sub>	Bacterial	Infection
Sulfamethazine-d₄ is a deuterium labeled Sulfamethazine (Sulfadimidine). Sulfamethazine is an antimicrobial that is widely used to treat and prevent various animal diseases (such as gastrointestinal and respiratory tract infections)[1][2].

HY-B1217S

Bronopol-d4 BNPD-d<sub>4sub>; BNPK-d<sub>4sub>	Isotope-Labeled Compounds Bacterial	Infection
Bronopol-d₄ is deuterium labeled Bronopol.

HY-W014839S1

Cyclamic acid-d4 sodium Cyclohexylsulfamic acid-sub>d<sub>4sub> sodium; Sodium cyclamate-sub>d<sub>4sub>	Isotope-Labeled Compounds	Others
Cyclamic acid-d4 (sodium) is the deuterium labeled Cyclamic acid (sodium) .

HY-157075S

(Z)-Rilpivirine-d4 R278474-d<sub>4sub>; TMC278-d<sub>4sub>; DB08864-d<sub>4sub>	Isotope-Labeled Compounds	Others
(Z)-Rilpivirine-d₄ (R278474-d₄; TMC278-d₄; DB08864-d₄) is deuterium-labeled (Z)-Rilpivirine .

HY-15455S

Roflumilast-d4 APTA-2217-d<sub>4sub>; BYK 20869-d<sub>4sub>; B9302-107-d<sub>4sub>	Isotope-Labeled Compounds Phosphodiesterase (PDE) RSV	Inflammation/Immunology
Roflumilast-d₄ is the deuterium labeled Roflumilast. Roflumilast is a selective PDE4 inhibitor with IC50s of 0.7, 0.9, 0.7, and 0.2 nM for PDE4A1, PDEA4, PDEB1, and PDEB2, respectively, without affecting PDE1, PDE2, PDE3 or PDE5 isoenzymes from various cells[1][2].

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-125833

Alpha-Naphthoflavone 5+ Cited Publications	Flavonoids Flavones Source classification Indigofera heterantha Wall. ex Brand. Plants Compositae Disease Research Fields Cancer	Cytochrome P450 Aryl Hydrocarbon Receptor Apoptosis
Alpha-Naphthoflavone is an orally active flavonoid that is a potent, competitive inhibitor of aromatase< b>aromatase. < b > IC < sub > 50 < / sub > < / b > and < b > K < sub > I < / sub > < / b > value were 0.5 and 0.2 microns. Alpha-Naphthoflavone can inhibit cell proliferation and induce apoptosis ^[4].

HY-W751835

Baloxavir-d4 Maximum Cited Publications 30 Publications Verification Baloxavir acid-d<sub>4sub>; S-033447-d<sub>4sub>	Classification of Application Fields Disease Research Fields Cancer	Isotope-Labeled Compounds
Baloxavir-d₄ (Baloxavir acid-d₄; S-033447-d₄) is the deuterium-labeled Baloxavir (HY-109025A). Baloxavir-d₄ (Baloxavir-d₄ acid), derived from the proagent Baloxavir-d₄ marboxil, is a first-in-class, potent and selective cap-dependent endonuclease (CEN) inhibitor within the polymerase PA subunit of influenza A and B viruses. Baloxavir-d₄ inhibits viral RNA transcription and replication and has potently antiviral activity .

HY-W011474

Geranylgeraniol	Structural Classification Natural Products Microorganisms	NF-κB
Geranylgeraniol is an orally acitve vitamin K₂ sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model ^[4].

HY-P2274

Argifin	Infection Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields	Parasite
Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms, with IC₅₀s of 0.025 μM, 6.4 μM , 1.1 μM and 4.5 μM for SmChiA (Serratia marcescens chitinaese A), SmChiB, Aspergillus fumigatus chitinase B1 and human chitotriosidase, respectively .

HY-N0662

Amentoflavone 5+ Cited Publications Didemethyl-ginkgetin	Structural Classification Flavonoids Classification of Application Fields Source classification Phenols Polyphenols Selaginellaceae Plants Biflavones Selaginella tamariscina (P. Beauv.) Spring Disease Research Fields Cancer	Reactive Oxygen Species Apoptosis Bacterial Fungal RSV GABA Receptor
Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active GABA(A) negative modulator. Amentoflavone also shows anti-inflammatory, antioxidative, anti-viral, anti-tumor, anti-radiation, anti-fungal, antibacterial activity. Amentoflavone induces apoptosis and cell cycle arrest at sub-G1 phase ^[4].

HY-P99294

Ganitumab AMG 479; Human Anti-IGF1R Recombinant Antibody	Classification of Application Fields Disease Research Fields Cancer	IGF-1R
Ganitumab (AMG 479) is a recombinant human monoclonal antibody to the human type 1 insulin-like growth factor receptor (IGF1R). Ganitumab recognizes murine IGF1R with sub-nanomolar affinity (K_D=0.22 nM) and inhibits the interaction of murine IGF1R with IGF1 and IGF2. Ganitumab can be used in research of cancer .

HY-N11799

Neochilenin 3-O-Methylquercetin 4′-O-glucoside	Structural Classification Flavonoids Source classification Plants Compositae Other Flavonoids	Others
Neochilenin (3-O-Methylquercetin 4 '-O-glucoside) is a glycoside of 3-O-methylquercetin, which can be isolated from the sub-family Cereoideae (Cactaceae). .

HY-N10192

Aculene D	Infection Microorganisms Classification of Application Fields Terpenoids Sesquiterpenes Source classification Disease Research Fields	Endogenous Metabolite Bacterial
Aculene D, a fungal metabolite, shows quorum sensing (QS) inhibitory activity against Chromobacterium violaceum CV026, and could significantly reduce violacein production in N-hexanoyl-l-homoserine lactone (C6-HSL) induced C. violaceum CV026 cultures at sub-inhibitory concentrations .

HY-W011474R

Geranylgeraniol (Standard)	Structural Classification Natural Products Microorganisms	NF-κB
Geranylgeraniol (Standard) is the analytical standard of Geranylgeraniol. This product is intended for research and analytical applications. Geranylgeraniol is an orally acitve vitamin K2 sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model ^[3][4].

HY-N0662R

Amentoflavone (Standard)	Structural Classification Flavonoids Source classification Phenols Polyphenols Selaginellaceae Plants Biflavones Selaginella tamariscina (P. Beauv.) Spring	Reactive Oxygen Species Apoptosis Bacterial Fungal RSV GABA Receptor
Amentoflavone (Standard) is the analytical standard of Amentoflavone. This product is intended for research and analytical applications. Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active GABA(A) negative modulator. Amentoflavone also shows anti-inflammatory, antioxidative, anti-viral, anti-tumor, anti-radiation, anti-fungal, antibacterial activity. Amentoflavone induces apoptosis and cell cycle arrest at sub-G1 phase ^[4].

HY-B0504S

Creatinine-d3 3 Publications Verification NSC13123-d<sub>3sub>	Classification of Application Fields Metabolic Disease Disease Research Fields	Endogenous Metabolite
Creatinine-d₃ is a deuterium labeled Creatinine. Creatinine is a break-down product of creatine phosphate in muscle[1].

HY-N8208

Sibiricose A1	Monophenols Classification of Application Fields Simple Phenylpropanols Source classification Polygalaceae Other Diseases Phenols Polygala sibirica Linn. Phenylpropanoids Plants Disease Research Fields	Others
Sibiricose A1is an oligosaccharide ester that can be found in Polygala tenuifolia .

HY-N12066

Progenin III palmitate	Structural Classification Cardiacglycosides Source classification Plants Dioscorea cayenensis Lam. Steroids Dioscoreaceae	Others
Progenin III palmitate is a steroid glycoside ester isolated from Dioscorea cayenensis rhizomes .

HY-W017439

Ethyl benzoate	Structural Classification Natural Products Microorganisms Source classification Artemisia monosperma Delile Plants Compositae	Others
Ethyl benzoate is ester from oil of the overground parts of Artemisia monosperma_[1].

HY-W017439R

Ethyl benzoate (Standard)	Structural Classification Natural Products Microorganisms Artemisia monosperma Delile Source classification Plants Compositae	Others
Ethyl benzoate (Standard) is the analytical standard of Ethyl benzoate. This product is intended for research and analytical applications. Ethyl benzoate is ester from oil of the overground parts of Artemisia monosperma .

HY-N3291

Methyl-3-(2,4-dihydroxy phenyl) propanoate	Tephrosia villosa (L.) Pers. Source classification Phenols Plants Compositae	Others
Methyl-3-(2,4-dihydroxy phenyl) propanoate is a phenylpropanoic ester with antifeedant activity .

HY-113972

Methyl mycophenolate	Structural Classification Monophenols Microorganisms Classification of Application Fields Marine natural products Phenols Inflammation/Immunology Disease Research Fields Marine microorganism	Others
Methyl mycophenolate is a methyl ester of mycophenolic acid and is also found in marine-derived fungus Phaeosphaeria spartinae .

HY-N6593

Arillanin A	Classification of Application Fields Simple Phenylpropanols Source classification Polygalaceae Other Diseases Phenols Polyphenols Phenylpropanoids Plants Disease Research Fields Polygala tenuifolia Willd.	Others
Arillanin A is an oligosaccharide ester isolated from Polygala arillata.

HY-N1854

Pinobanksin 3-acetate	Flavanonols Structural Classification Flavonoids Animals Classification of Application Fields Other Diseases Scrophulariaceae Eremophila alternifolia Plants Disease Research Fields	Others
Pinobanksin 3-acetate is a one of Pinobanksin ester derivatives that can be isolated from Sonoran propolis .

HY-W102375

4-Acetoxycinnamic acid	Structural Classification Kaempferia galanga L. Classification of Application Fields Simple Phenylpropanols Source classification Phenylpropanoids Plants Inflammation/Immunology Disease Research Fields Zingiberaceae	Others
4-Acetoxycinnamic acid is an acetate ester obtained by the formal condensation of the hydroxy group of trans-4-coumaric acid with acetic acid. 4-Acetoxycinnamic acid is a member of cinnamic acids and a member of phenyl acetates. 4-Acetoxycinnamic acid derives from a trans-4-coumaric acid .

HY-123487

Sapintoxin A	Structural Classification Natural Products Source classification Euphorbiaceae Shirakiopsis indica (Willd.) Esser Plants	Others
Sapintoxin A is a phorbol ester that can be isolated from the unripe fruits of Sapium indicum .

HY-W009082

Methyl behenate Methyl docosanoate	Structural Classification Natural Products other families Classification of Application Fields Source classification Other Diseases Plants Disease Research Fields	Others
Methyl behenate (Methyl docosanoate) is a naturally fatty acid methyl ester isolated from the plant of Aspidopterys obcordata Lemsl .

HY-134607

(E)-Benzyl ferulate Benzyl (E)-p-coumarate	Structural Classification Animals Simple Phenylpropanols Source classification Phenylpropanoids	Others
(E)-Benzyl ferulate is a phenolic ester that can be isolated from Thai propolis .

HY-N3649

Cuniloside B Eucalmaidin E	Structural Classification Other Monoterpenes Terpenoids Source classification Myrtaceae Plants Eucalyptus robusta Smith	Others
Cuniloside B (Eucalmaidin E) is a non-volatile glucose monoterpene ester. Cuniloside B can be used as a fragrance additive .

HY-N12506

Cimicifugic acid F	Structural Classification Ketones, Aldehydes, Acids Source classification Ranunculaceae Phenols Polyphenols Plants Cimicifuga racemosa (L.) Nutt.	Others
Cimicifugic acid F is a hydroxycinnamic acid ester of piscidic acid isolated from the rhizomes of Cimicifuga racemosa.

HY-124422

Pentacosanoic acid	other families Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Plants Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Pentacosanoic acid is a 25-carbon long-chain saturated fatty acid. Pentacosanoic is a conjugate acid of a pentacosanoate .

HY-W011688

Methyl palmitoleate 1 Publications Verification (Z)-Methyl hexadec-9-enoate; Methyl cis-9-Hexadecenoate	Structural Classification Natural Products other families Classification of Application Fields Source classification Other Diseases Plants Disease Research Fields	Others
Methyl palmitoleate ((Z)-Methyl hexadec-9-enoate), a fatty acid methyl ester, is an analogue of Palmitoleate with cytoprotective and growth-promoting properties .

HY-N2073

Ethyl linolenate	Cardiovascular Disease Structural Classification Natural Products other families Classification of Application Fields Source classification Plants Disease Research Fields	MCHR1 (GPR24)
Ethyl linolenate is a fatty acid ethyl ester (FAEE). Ethyl linolenate plays an active role in inhibition of the cellular production on melanin with an IC₅₀ of 70 μM. Anti-melanogenesis Effects .

HY-N3159

Octadecyl caffeate	Structural Classification Source classification Phenols Polyphenols Plants Merremia tuberosa (L.) Rendle Convolvulaceae	Others
Octadecyl caffeate is a caffeate ester that can be isolated from Merremia tuberosa .

HY-N12237

Condurango glycoside A0	Apocynaceae Structural Classification Marsdenia cundurango Rchb.f. Polysaccharides Source classification Plants Saccharides	Others
Condurango glycoside A0 is a pregnane ester glycoside that can be isolated from Marsdema cundurango .

HY-N2890

Arillatose B 6'-O-Feruloylsucrose	Aristolochia cretica Lam. Structural Classification Monophenols Source classification Phenols Plants Aristolochiaceae	Others
Arillatose B is a sucrose ester that can be isolated from the roots of the Greek endemic species Aristolochia cretica .

HY-W013214

Ethyl arachidonate	Structural Classification Natural Products Source classification Endogenous metabolite	Endogenous Metabolite
Ethyl arachidonate is a lipophilic esterified form of arachidonic acid (AA) and can be added into dietary regimens or fed to cultured cells as a source of exogenous arachidonate. Ethyl arachidonate is the main species of fatty acid ethyl esters (FAEE) in brain of alcohol-intoxicated subjects .

HY-125545

Cynanester A	Structural Classification Terpenoids Source classification Cnidoscolus vitifolius (Mill.) Pohl Euphorbiaceae Plants Pentacyclic Triterpenoids	Others
Cynanester A is a active product that can be isolated from Cynanchum chinense R. Br. .

HY-W011688R

Methyl palmitoleate (Standard)	Structural Classification Natural Products other families Source classification Plants	Others
Methyl palmitoleate (Standard) is the analytical standard of Methyl palmitoleate. This product is intended for research and analytical applications. Methyl palmitoleate ((Z)-Methyl hexadec-9-enoate), a fatty acid methyl ester, is an analogue of Palmitoleate with cytoprotective and growth-promoting properties .

HY-118442

Sphingosine (d14:1) Tetradecasphing-4-enine	Natural Products Animals Classification of Application Fields Source classification Disease Research Fields Cancer	PKC
Sphingosine (d14:1) (Tetradecasphing-4-enine), a sphingolipid, is a potent Protein kinase C (PKC) inhibitor. Sphingosine (d14:1) prevents its interaction with sn-1,2-diacylglycerol (DAG)/Phorbol esters .

HY-N10788

Pomonic acid	Triterpenes Structural Classification Terpenoids Verbenaceae Source classification Plants Lantana camaraLinn.	Acyltransferase
Pomonic acid is a triterpenoid that significantly inhibits cholesterol ester accumulation and suppresses the acyl coenzyme A:cholesterol acyltransferase (ACAT) activity .

HY-N9777

Procyanidin B-5 3,3'-di-O-gallate	Structural Classification Rheum palmatum L. Polygonaceae Source classification Phenols Polyphenols Plants	Others
Procyanidin B-5 3,3'-di-O-gallate is a potent inhibitor of squalene epoxidase with an IC₅₀ of 0.55 μM. Procyanidin B-5 3,3'-di-O-gallate reduces cholesterol by inhibiting squalene epoxidase activity .

HY-135087

Caprylic/Capric Triglyceride 1 Publications Verification	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Cosmetic Research Palmae Plants Disease Research Fields Trachycarpus fortunei (Hook.) H. Wendl.	Biochemical Assay Reagents
Caprylic/Capric Triglyceride is the triglycerides and esters prepared from fractionated vegetable oil sources and fatty acids from coconuts and palm kernel oils. Caprylic/Capric Triglyceride possesses excellent oxidation stability. Caprylic/Capric Triglyceride is used as a food additive and used in cosmetics .

HY-125531

Dactylorhin A	Bletilla striata (Thunb. ex Murray) Rchb. f. Classification of Application Fields Ketones, Aldehydes, Acids Orchidaceae Source classification Other Diseases Plants Disease Research Fields	Others
Dactylorhin A, a succinate derivative ester, is isolated from rhizomes of Gymnadenia conopsea. Dactylorhin A exhibits moderate inhibitory effects on NO production effects in RAW 264.7 macrophage cells .

HY-W440039

Methyl 2-(2,4-dihydroxyphenyl)acetate 1 Publications Verification	Source classification Plants	Others
Methyl 2-(2,4-dihydroxyphenyl)acetate, a phenolic ester, is isolated from Nigella damascena seeds with selective phytotoxic effects .

HY-N10697

Angulatin G Celangulatin E	Structural Classification Terpenoids Sesquiterpenes Source classification Celastraceae Celastrus angulatus Maxim. Plants	Parasite
Angulatin G (Celangulatin E) is an insecticidal sesquiterpene polyol ester with a β-dihydroagarofuran sesquiterpene skeleton, which can be isolated from the root bark of Celastrus angulatus. Angulatin G shows LD₅₀ against Mythimna separata of 1656.4 μg/mL .

HY-N7939

Celangulin XIX	Structural Classification Terpenoids Sesquiterpenes Source classification Celastraceae Celastrus angulatus Maxim. Plants	Others
Celangulin XIX is a insecticidal that can be isolated from Celastrus angulatu. Celangulin XIX has strong insecticidal activity against Mythimna separate with an ED₅₀ of 73.3 μg/g .

HY-N10695

Celangulatin C	Structural Classification Pinaceae Terpenoids Sesquiterpenes Source classification Pseudolarix amabilis (J. Nelson) Rehder Plants	Parasite
Celangulatin C is an insecticidal sesquiterpene polyol ester, that can be isolated from the root bark of Pseudolarix kaempferi. Celangulatin C shows LD₅₀ against Mythimna separata of 280.4 μg/mL .

HY-B0987

Ascorbyl palmitate 3 Publications Verification L-Ascorbic acid 6-hexadecanoate; 6-O-Palmitoyl-L-ascorbic acid	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Cancer	Reactive Oxygen Species Endogenous Metabolite Calcium Channel Sodium Channel Apoptosis NOD-like Receptor (NLR) Bcl-2 Family Caspase
Ascorbyl palmitate is an orally active ester formed from ascorbic acid and palmitic acid, used as an antioxidant and food additive. Ascorbyl palmitate in preventing fat and oil oxidation is more efficient than Butylated hydroxyanisole (HY-B1066) and Butylated hydroxytoluene (HY-Y0172). Ascorbyl palmitate mitigates inhibition of collagen synthesis by select calcium and sodium channel blockers. Ascorbyl palmitate induces Apoptosis in human umbilical vein endothelial cells (HUVECs). Ascorbyl palmitate ameliorates inflammatory diseases by inhibition of NLRP3 inflammasome ^[4].

HY-N2098

Obtusifolin	Seeds of Cassia tora Linn. Structural Classification Classification of Application Fields Source classification Plants Quinones other families Leguminosae Anthraquinones Phenols Polyphenols Disease Research Fields Cancer	NF-κB
Obtusifolin, isolated from the seeds of Cassia obtusifolia, regulates the gene expression and production of MUC5AC mucin in airway epithelial cells via inhibiting NF-kB pathway . Obtusifolin suppresses phthalate esters-induced breast cancer bone metastasis by targeting parathyroid hormone-related protein .

HY-117586

9-PAHPA	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite
9-PAHPA is a fatty acid esters of hydroxy fatty acid (FAHFA). FAHFAs are a new family of endogenous lipids, have antidiabetic and anti-inflammatory effects .

HY-N2098R

Obtusifolin (Standard)	Seeds of Cassia tora Linn. Quinones Structural Classification other families Leguminosae Anthraquinones Source classification Phenols Polyphenols Plants	NF-κB
Obtusifolin (Standard) is the analytical standard of Obtusifolin. This product is intended for research and analytical applications. Obtusifolin, isolated from the seeds of Cassia obtusifolia, regulates the gene expression and production of MUC5AC mucin in airway epithelial cells via inhibiting NF-kB pathway . Obtusifolin suppresses phthalate esters-induced breast cancer bone metastasis by targeting parathyroid hormone-related protein .

HY-N12239

Condurango glycoside E	Apocynaceae Marsdenia cundurango Rchb.f. Source classification Plants	Others
Condurango glycoside E is a glycoside compound that can be isolated from the bark extract of Marsdenia cundurango .

Cat. No.	Product Name	Chemical Structure

HY-66005S

Acetaminophen-d4
Acetaminophen-d₄ is the deuterium labeled Acetaminophen. Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM; is a widely used antipyretic and analgesic agent[1][2][3]. Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor[4].

HY-Y1042S

4-Cyanophenol-d4
4-Cyanophenol-d₄ is the deuterium labeled 4-Cyanophenol[1].

HY-B1008S

4-Aminobenzoic acid-d4
4-Aminobenzoic acid-d₄ is the deuterium labeled 4-Aminobenzoic acid. 4-Aminobenzoic acid is an intermediate in the synthesis of folate by bacteria, plants, and fungi.

HY-N0006S1

Demethoxycurcumin-d4
Demethoxycurcumin-d₄ is the deuterium labeled Demethoxycurcumin. Demethoxycurcumin (Curcumin II) is a major active curcuminoid; possess anti-inflammatory properties[1].

HY-118431S2

DMABA-d6 NHS ester
DMABA-d₆ NHS ester is the deuterium labeled DMABA NHS ester[1].

HY-118431S3

DMABA-d10 NHS ester
DMABA-d₁₀ NHS ester is the deuterium labeled DMABA NHS ester[1].

HY-118431S

DMABA-d4 NHS ester
DMABA-d₄ NHS ester is the deuterium labeled DMABA NHS ester[1].

HY-10844S1

Pretomanid-d5
Pretomanid-d₅ is deuterated labeled Pretomanid (HY-10844). Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 μg/mL.

HY-41680S

4-Aminobenzonitrile-d4
4-Aminobenzonitrile-d₄ is the deuterium labeled 4-Aminobenzonitrile[1].

HY-17413S2

Zidovudine-d4
Zidovudine-d₄ is deuterated labeled Zidovudine (HY-17413). Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection. Zidovudine increases CRISPR/Cas9-mediated editing frequency.

HY-B0329S

Isoniazid-d4
Isoniazid-d₄ is the deuterium labeled Isoniazid. Isoniazid (INH) is a proagent and must be activated by a bacterial catalase-peroxidase enzyme KatG. Isoniazid is bactericidal to rapidly dividing mycobacteria and has anti-tuberculostatic activity[1][2][3][4].

HY-100048S

Acetylisoniazid-d4
Acetylisoniazid-d₄ is the deuterium labeled Acetylisoniazid[1].

HY-118861S

Enclomiphene-d4 hydrochloride
Enclomiphene-d₄ (hydrochloride) is a deuterium labeled Enclomiphene. Enclomiphene-d₄ (hydrochloride) is a potent and orally active oestrogen receptor antagonist, with antioestrogenic property[1].

HY-109015S

Tucidinostat-d4
Tucidinostat-d₄ is the deuterium labeled Tucidinostat. Tucidinostat is a potent and orally bioavailable HDAC enzymes class I (HDAC1/2/3) and class IIb (HDAC10) inhibitor, with IC50s of 95, 160, 67 and 78 nM, respectively[1].

HY-19696AS

Tauroursodeoxycholate-d4 sodium
Tauroursodeoxycholate-d₄ (sodium) is the deuterium labeled Tauroursodeoxycholate sodium. Tauroursodeoxycholate (Tauroursodeoxycholic acid; TUDCA) sodium is an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12. Tauroursodeoxycholate also inhibits ERK.

HY-19696S1

Tauroursodeoxycholate-d4
Tauroursodeoxycholate-d₄ is deuterium labeled Tauroursodeoxycholate. Tauroursodeoxycholate (Tauroursodeoxycholic acid) is an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12. Tauroursodeoxycholate also inhibits ERK.

HY-B0389S24

D-Glucose-d4
D-Glucose-d₄ is the deuterium labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molec

HY-B0696AS

Tiagabine-d4 hydrochloride
Tiagabine-d₄ hydrochloride is deuterated labeled Tiagabine hydrochloride (HY-B0696A). Tiagabine hydrochloride is a potent and selective GABA reuptake inhibitor, used as an anticonvulsant agent, with IC₅₀s of 67, 446 and 182 nM for [ ³H]GABA uptake in Synaptosomes, Neurons and Glia, respectively .

HY-13273S

Ostarine-d4
Ostarine-d4 is a deuterated labeled Ostarine .

HY-34498S

4-Chloro-2-methylphenol-d4
4-Chloro-2-methylphenol-d₄ is the deuterium labeled 4-Chloro-2-methylphenol[1].

HY-10581AS1

Gatifloxacin-d4 hydrochloride
Gatifloxacin-d₄ (AM-1155-d₄; BMS-206584-d₄; PD135432-d₄) hydrochloride is deuterium-labeled Gatifloxacin (hydrochloride) (HY-10581A) .

HY-107542S

Oleoylethanolamide-d4
Oleoylethanolamide-d₄ is the deuterium labeled Oleoylethanolamide. Oleoylethanolamide is a high affinity endogenous PPAR-α agonist, which plays an important role in the treatment of obesity and arteriosclerosis.

HY-B0017S

Telbivudine-d4
Telbivudine-d₄ is deuterium labeled Telbivudine. Telbivudine (Epavudine), an orally active thymidine nucleoside analog, is a potent antiviral inhibitor of hepatitis B virus (HBV) replication[1].

HY-B0579S

Cyclosporin A-d4
Cyclosporin A-d₄ is the deuterium labeled Cyclosporin A. Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of calcineurin with an IC50 of 5 nM. Cyclosporin A also inhibits CD11a/CD18 ad

HY-N5034S

Phosphorylethanolamine-d4
Phosphorylethanolamine-d₄ (Monoaminoethyl phosphate-d₄; NSC 254167-d₄) is a deuterium labeled Phosphorylethanolamine (HY-N5034). Phosphorylethanolamine is an endogenous metabolite.

HY-16582AS

Sonidegib-d4
Sonidegib-d4 is a isotope of Sonidegib. Sonidegib is a potent and selective Smo antagonist with IC₅₀ of 1.3 nM and 2.5 nM for mouse and human Smo in binding assay, respectively .

HY-W700069

Gatifloxacin-d4
Gatifloxacin-d4 is the deuterium labeled Gatifloxacin .

HY-78004S1

1,2-Diphenylethane-d4
1,2-Diphenylethane-d4 (Dibenzil-d4; s-Diphenylethane-d4; Bibenzyl-d4) is the deuterium labeled Bibenzyl (HY-78004) .

HY-17422S1

Acyclovir-d4

Acyclovir-d₄ is the deuterium labeled Acyclovir. Acyclovir (Aciclovir) is a guanosine analogue and an orally active antiviral agent. Acyclovir inhibits HSV-1 (IC50 of 0.85 μM), HSV-2 (IC50 of 0.86 μM) and varicella-zoster virus. Acyclovir can be phosphorylated by viral thymidine kinase (TK), and Acyclovir triphosphate interferes with viral DNA polymerization through competitive inhibition with guanosine triphosphate and obligatory chain termination[1][2][3]. Acyclovir prevents bacterial infections during induction therapy for acute leukaemia[4].

HY-B0548AS1

Hydroxyzine-d4' dihydrochloride
Hydroxyzine-d₄ (dihydrochloride) is the deuterium labeled Hydroxyzine dihydrochloride. Hydroxyzine dihydrochloride, a benzodiazepine antihistamine agent, acts as a orally active histamine H1-receptor and serotonin antagonist. Hydroxyzine dihydrochloride has anxiolytic effect and can be used forthe research of generalised anxiety disorder[1][2].

HY-B0035S

Sulfamethazine-d4
Sulfamethazine-d₄ is a deuterium labeled Sulfamethazine (Sulfadimidine). Sulfamethazine is an antimicrobial that is widely used to treat and prevent various animal diseases (such as gastrointestinal and respiratory tract infections)[1][2].

HY-B1217S

Bronopol-d4
Bronopol-d₄ is deuterium labeled Bronopol.

HY-W014839S1

Cyclamic acid-d4 sodium
Cyclamic acid-d4 (sodium) is the deuterium labeled Cyclamic acid (sodium) .

HY-157075S

(Z)-Rilpivirine-d4
(Z)-Rilpivirine-d₄ (R278474-d₄; TMC278-d₄; DB08864-d₄) is deuterium-labeled (Z)-Rilpivirine .

HY-15455S

Roflumilast-d4
Roflumilast-d₄ is the deuterium labeled Roflumilast. Roflumilast is a selective PDE4 inhibitor with IC50s of 0.7, 0.9, 0.7, and 0.2 nM for PDE4A1, PDEA4, PDEB1, and PDEB2, respectively, without affecting PDE1, PDE2, PDE3 or PDE5 isoenzymes from various cells[1][2].

HY-B1431S

Butylparaben-d4
Butylparaben-d₄ is the deuterium labeled Butylparaben. Butylparaben is an organic compound, has proven to be a highly successful antimicrobial preservative in cosmetics, also used in medication suspensions, and as a flavoring additive in food.

HY-N0570S

Hydroxytyrosol-d4
Hydroxytyrosol-d₄ is the deuterium labeled Hydroxytyrosol. Hydroxytyrosol (DOPET) is a phenolic compound drawn from the olive tree and its leaves with anti-oxidant, anti-atherogenic, anti-thrombotic, antimicrobial, anti-inflammatory and anti-tumour effects[1][2].

HY-B1290S

2-Phenylethanol-d4

2-Phenylethanol-d₄ is the deuterium labeled 2-Phenylethanol[1]. 2-Phenylethanol (Phenethyl alcohol), extracted from rose, carnation, hyacinth, Aleppo pine, orange blossom and other organisms, is a colourless liquid. It has a pleasant floral odor and also an autoantibiotic produced by the fungus Candida albicans[2]. It is used as an additive in cigarettes and also used as a preservative in soaps due to its stability in basic conditions.

HY-Y1630S

NSC 10281-d4
NSC 10281-d₄ is the deuterium labeled NSC 10281[1].

HY-N2037AS

Higenamine-d4 hydrochloride
Higenamine-d₄ (Norcoclaurine-d₄; Demethyl-Coclaurine-d₄) hydrochloride is deuterium-labeled Higenamine (hydrochloride) (HY-N2037A) .

HY-B0213S

Sulfameter-d4
Sulfameter-d₄ (Sulfametoxydiazine-d₄; 5-Methoxysulfadiazine-d₄)is the deuterium labeledSulfameter(HY-B0213) . Sulfameter (Sulfametoxydiazine; 5-Methoxysulfadiazine) is an effective long-acting sulfonamide antibiotic with antibacterial activities. Sulfameter can be used for the research of urinary tract infections and lepriasis .

HY-B0217S

Nitazoxanide-d4
Nitazoxanide-d₄ is the deuterium labeled Nitazoxanide, which is an antiprotozoal agent.

HY-N1150S1

Thymidine-d4
Thymidine-d₄ is the deuterium labeled Thymidine. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication[1][2][3].

HY-14744S

Levamlodipine-d4
Levamlodipine-d₄ is the deuterium labeled Levamlodipine. Levamlodipine ((S)-Amlodipine) is a powerful dihydropyridine calcium channel blocker, possessing vasodilation properties and used in the treatment of hypertension and angina[1].

HY-17043S

Loratadine-d4
Loratadine-d₄ is the deuterium labeled Loratadine. Loratadine (SCH-29851) is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM. Loratadine has anti-dengue-virus (DENV) activity. Loratadine can inhibit immunologic release of inflammatory mediators.

HY-118901S

Opipramol-d4
Opipramol-d₄ is the deuterium labeled Opipramol[1].

HY-B1826S2

Adefovir-d4
Adefovir-d₄ is the deuterium labeled Adefovir. Adefovir (GS-0393) is an adenosine monophosphate analog antiviral agent that after intracellular conversion to Adefovir diphosphate inhibits HBV DNA polymerase. Adefovir has an IC50 of 0.7 μM against HBV in the HepG2.2.15 cell line. Adefovir has good antiviral activity against several viruses, including HBV and herpesviruses[1][2][3].

HY-B0105S1

Ketoconazole-d4
Ketoconazole-d₄ is the deuterium labeled Ketoconazole. Ketoconazole (R-41400) is an imidazole anti-fungal agent, a CYP3A4 and CYP24A1 inhibitor.

HY-B0272S2

Rifampicin-d4
Rifampicin-d₄ is the deuterium labeled Rifampicin. Rifampicin is a potent and broad spectrum antibiotic against bacterial pathogens. Rifampicin has anti-influenza virus activities.

HY-14654S1

Aspirin-d4
Aspirin-d₄ is the deuterium labeled Aspirin. Aspirin is a non-selective and irreversible inhibitor of COX-1 and COX-2 with IC50s of 5 and 210 μg/mL[1][2].

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