Search Result

Results for "

cis-4’-Hydroxy CCNU Lomustine-d<sub>4</sub>

" in MedChemExpress (MCE) Product Catalog:

By Targets:	P-glycoprotein (10) 11β-HSD (3) 5 alpha Reductase (4) 5-HT Receptor (73) Acetolactate Synthase (ALS) (1) ADC Cytotoxin (11) ADC Linker (26) Adenosine Deaminase (1) Adenosine Receptor (8) Adrenergic Receptor (80) AIM2 (1) Akt (4) Aldehyde Dehydrogenase (ALDH) (1) Amino Acid Derivatives (10) Aminopeptidase (1) AMPK (6) Amyloid-β (8) Anaplastic lymphoma kinase (ALK) (8) Androgen Receptor (18) Angiotensin Receptor (22) Angiotensin-converting Enzyme (ACE) (14) Antibiotic (156) Antifolate (5) Apical Sodium-Dependent Bile Acid Transporter (2) Apolipoprotein (1) Apoptosis (239) Arginase (4) Aryl Hydrocarbon Receptor (5) ATM/ATR (1) ATP Citrate Lyase (2) ATP Synthase (1) Aurora Kinase (1) Autophagy (271) Bacterial (252) Bcl-2 Family (3) Bcr-Abl (10) BCRP (2) Beta-lactamase (1) Beta-secretase (1) Biochemical Assay Reagents (86) Btk (4) c-Fms (2) c-Kit (15) c-Met/HGFR (5) Calcineurin (2) Calcium Channel (58) Cannabinoid Receptor (15) Carbonic Anhydrase (7) Casein Kinase (1) Caspase (5) CaSR (2) Cathepsin (1) CD73 (1) CDK (10) CFTR (5) CGRP Receptor (1) Checkpoint Kinase (Chk) (1) Chloride Channel (2) Cholinesterase (ChE) (18) Complement System (6) COMT (5) COX (66) CRISPR/Cas9 (3) Cuproptosis (1) CXCR (1) Cyclophilin (2) Cytochrome P450 (29) Deubiquitinase (1) Dihydroorotate Dehydrogenase (1) Dipeptidyl Peptidase (14) Disulfidptosis (4) DNA Alkylator/Crosslinker (10) DNA Methyltransferase (2) DNA/RNA Synthesis (73) Dopamine Receptor (45) Dopamine Transporter (1) Drug Metabolite (100) Drug-Linker Conjugates for ADC (12) Dynamin (1) DYRK (2) E1/E2/E3 Enzyme (2) E3 Ligase Ligand-Linker Conjugates (2) EBI2/GPR183 (1) EGFR (20) Elastase (2) Endogenous Metabolite (852) Endothelin Receptor (3) Enterovirus (6) Epigenetic Reader Domain (6) ERK (7) Estrogen Receptor/ERR (41) Factor Xa (5) FAK (1) Fatty Acid Synthase (FASN) (3) Ferroptosis (45) FGFR (11) FKBP (3) Flavivirus (2) FLT3 (10) Fluorescent Dye (6) Fungal (65) FXR (4) G protein-coupled Bile Acid Receptor 1 (2) GABA Receptor (27) Gap Junction Protein (2) Glucocorticoid Receptor (30) Glucosidase (2) Glucosylceramide Synthase (GCS) (2) Glutathione Peroxidase (1) Glutathione Reductase (1) Glutathione S-transferase (1) GlyT (2) GnRH Receptor (3) GPR109A (2) GPR35 (1) GPR55 (2) GSK-3 (3) HBV (11) HCV (18) HCV Protease (3) HDAC (16) Hedgehog (3) Hexokinase (1) HIF/HIF Prolyl-Hydroxylase (2) Histamine Receptor (32) Histone Acetyltransferase (5) Histone Demethylase (7) Histone Methyltransferase (3) HIV (51) HIV Integrase (11) HIV Protease (7) HMG-CoA Reductase (HMGCR) (32) HSP (4) HSV (11) IGF-1R (3) iGluR (26) IKK (2) Imidazoline Receptor (3) Immune Checkpoint (1) Indoleamine 2,3-Dioxygenase (IDO) (1) Influenza Virus (28) Insulin Receptor (1) Integrin (2) Interleukin Related (8) IRE1 (3) Isotope-Labeled Compounds (2131) JAK (7) JNK (1) Keap1-Nrf2 (13) Ketohexokinase (2) Kinesin (1) Leukotriene Receptor (9) Ligands for E3 Ligase (8) Ligands for Target Protein for PROTAC (1) Liposome (8) Lipoxygenase (5) LPL Receptor (6) mAChR (35) MAGL (2) MDM-2/p53 (4) MEK (4) Melanocortin Receptor (1) Melatonin Receptor (9) mGluR (8) MicroRNA (2) Microtubule/Tubulin (18) Mineralocorticoid Receptor (10) Mitochondrial Metabolism (6) Mitophagy (35) MMP (4) Molecular Glues (9) Monoamine Oxidase (10) Monoamine Transporter (1) mTOR (2) Myosin (4) Na+/K+ ATPase (5) nAChR (13) NADPH Oxidase (1) Neprilysin (7) Neurokinin Receptor (3) NF-κB (36) NO Synthase (27) NOD-like Receptor (NLR) (3) Notch (6) Nuclear Factor of activated T Cells (NFAT) (1) Nuclear Hormone Receptor 4A/NR4A (2) Nucleoside Antimetabolite/Analog (72) OAT (1) Opioid Receptor (5) Orexin Receptor (OX Receptor) (1) Orthopoxvirus (10) Oxidative Phosphorylation (1) P2X Receptor (1) P2Y Receptor (7) p38 MAPK (3) PAK (8) Parasite (71) PARP (5) PCSK9 (1) PDGFR (19) PGC-1α (1) PGE synthase (1) Phosphatase (10) Phosphodiesterase (PDE) (21) Phospholipase (6) PI3K (3) PKA (3) PKC (7) Potassium Channel (25) PPAR (23) Progesterone Receptor (26) Prostaglandin Receptor (31) PROTAC Linkers (80) PROTACs (5) Protease Activated Receptor (PAR) (1) Proteasome (1) Proton Pump (22) PTHR (2) Raf (7) RANKL/RANK (1) RAR/RXR (5) Ras (3) Reactive Oxygen Species (48) Renin (2) RET (6) Reverse Transcriptase (8) ROS Kinase (5) RSV (7) SARS-CoV (36) Ser/Thr Protease (3) Serotonin Transporter (24) SGLT (6) Sigma Receptor (1) Sirtuin (6) Small Interfering RNA (siRNA) (10) Sodium Channel (24) Src (7) STAT (5) Syk (1) TAM Receptor (3) Tau Protein (1) Telomerase (1) TGF-beta/Smad (5) TGF-β Receptor (1) Thrombin (8) Thrombopoietin Receptor (3) Thymidylate Synthase (5) Thyroid Hormone Receptor (7) TMV (1) TNF Receptor (8) Toll-like Receptor (TLR) (6) TOPK (1) Topoisomerase (24) Transthyretin (TTR) (1) Trk Receptor (3) TRP Channel (19) Tyrosinase (8) Vasopressin Receptor (1) VD/VDR (17) VEGFR (25) Virus Protease (15) Wee1 (1) Xanthine Oxidase (4) β-catenin (4) γ-secretase (1)
By Research Areas:	Cancer (919) Cardiovascular Disease (235) Endocrinology (202) Infection (424) Inflammation/Immunology (414) Metabolic Disease (553) Neurological Disease (437)
Click Chemistry:	DBCO (1) PROTAC Synthesis (1) Azide (3) Alkynes (18)
Oligonucleotides:	Nucleosides and their Analogs (12) Flavoring Agents (1) Pre-designed siRNA Sets (1) Phospholipids (11) Cationic Lipids (1) Polymers (3) Antisense Oligonucleotides (1) siRNAs (10)

3932

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

309

Natural
Products

Recombinant Proteins

3002

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Oligonucleotides

Targets Recommended: PIN1 P-glycoprotein

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-143979S

1-(2-Chloroethyl)-3-((1R,4R)-4-hydroxycyclohexyl)-1-nitrosourea-d4	Isotope-Labeled Compounds	Others
trans-4’-Hydroxy CCNU Lomustine-d₄ is the deuterium labeled trans-4’-Hydroxy CCNU Lomustine[1].

HY-13669

*Lomustine* 5 Publications Verification CCNU; NSC 79037	DNA Alkylator/Crosslinker Autophagy Apoptosis	Cancer
Lomustine (CCNU; NSC 79037) is a DNA alkylating agent, with antitumor activity.

HY-13669R

Lomustine (Standard) CCNU (Standard); NSC 79037 (Standard)	DNA Alkylator/Crosslinker Autophagy Apoptosis	Cancer
Lomustine (Standard) is the analytical standard of Lomustine. This product is intended for research and analytical applications. Lomustine (CCNU; NSC 79037) is a DNA alkylating agent, with antitumor activity.

HY-40136

cis-4-Hydroxy-L-proline	Endogenous Metabolite	Metabolic Disease Cancer
cis-4-Hydroxy-L-proline, a proline analogue, is an inhibitor of collagen production. cis-4-Hydroxy-L-proline could inhibit fibroblast growth by preventing the deposition of triple-helical collagen on the cell layer. cis-4-Hydroxy-L-proline also depresses the growth of primary N-nitrosomethylurea-induced rat mammary tumors ^[4].

HY-40136S

cis-4-Hydroxy-L-proline-d3	Isotope-Labeled Compounds Endogenous Metabolite	Cancer
cis-4-Hydroxy-L-proline-d₃ is the deuterium labeled cis-4-Hydroxy-L-proline. cis-4-Hydroxy-L-proline, a proline analogue, is an inhibitor of collagen production. cis-4-Hydroxy-L-proline could inhibit fibroblast growth by preventing the deposition of triple-helical collagen on the cell layer. cis-4-Hydroxy-L-proline also depresses the growth of primary N-nitrosomethylurea-induced rat mammary tumors[1][2][3][4].

HY-W002886

*N-Boc-cis-4-hydroxy-L-proline*	ADC Linker PROTAC Linkers	Cancer
N-Boc-cis-4-hydroxy-L-proline is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Boc-cis-4-hydroxy-L-proline is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[2

HY-W002887

*N-Boc-cis-4-Hydroxy-D-proline*	ADC Linker PROTAC Linkers	Cancer
N-Boc-cis-4-Hydroxy-D-proline is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Boc-cis-4-Hydroxy-D-proline is also a alkyl chain-based PROTAC linker that can be used in the Synthesis of ADCs or PROTACs.

HY-143978S

cis-4’-Hydroxy CCNU Lomustine-d4	Isotope-Labeled Compounds	Others
cis-4’-Hydroxy CCNU Lomustine-d₄ is the deuterium labeled cis-4’-Hydroxy CCNU Lomustine[1].

HY-40136R

cis-4-Hydroxy-L-proline (Standard)	Endogenous Metabolite	Metabolic Disease Cancer
cis-4-Hydroxy-L-proline (Standard) is the analytical standard of cis-4-Hydroxy-L-proline. This product is intended for research and analytical applications. cis-4-Hydroxy-L-proline, a proline analogue, is an inhibitor of collagen production. cis-4-Hydroxy-L-proline could inhibit fibroblast growth by preventing the deposition of triple-helical collagen on the cell layer. cis-4-Hydroxy-L-proline also depresses the growth of primary N-nitrosomethylurea-induced rat mammary tumors ^[3][4].

HY-W019213

cis-4-Hydroxy-L-proline hydrochloride	ADC Linker PROTAC Linkers	Cancer
cis-4-Hydroxy-L-proline hydrochloride is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). cis-4-Hydroxy-L-proline hydrochloride is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

HY-RS13999

SUB1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SUB1 Human Pre-designed siRNA Set A contains three designed siRNAs for SUB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SUB1 Human Pre-designed siRNA Set A SUB1 Human Pre-designed siRNA Set A

HY-146227

DNA topoisomerase II inhibitor 1	Topoisomerase Apoptosis	Cancer
DNA topoisomerase II inhibitor 1 (compound 8ed) is a potent DNA topoisomerase II inhibitor. DNA topoisomerase II inhibitor 1 shows anti-proliferative activity. DNA topoisomerase II inhibitor 1 induces apoptosis and cell cycle arrest at sub G1 phase .

HY-121385S1

Hydroxy Bosentan-d4 Ro 48-5033-d<sub>4sub>	Isotope-Labeled Compounds Endogenous Metabolite	Cardiovascular Disease
Hydroxy Bosentan-d₄ is deuterium labeled Hydroxy bosentan. Hydroxy bosentan (Ro 48-5033) is a primary metabolite of Bosentan (BOS) metabolized by the cytochrome P450 system in the liver. Ro 48-5033 assists BOS pharmacologically, retaining 10%-20% activities[1].

HY-115354S

*4-Hydroxy* Alprazolam-d5** 4-Hydroxyalprazolam-d<sub>5sub>; RS-4-Hydroxyalprazolam-d<sub>5sub>	Isotope-Labeled Compounds	Others
4-Hydroxy Alprazolam-d5 (4-Hydroxyalprazolam-d5; RS-4-Hydroxyalprazolam-d5) is the deuterium labeled 4-hydroxy Alprazolam (HY-115354) .

HY-W012927S

*4-Hydroxy-5-methylfuran-3(2H)-one-d3* Chicory furaneol-d<sub>3sub>	Isotope-Labeled Compounds	Others
4-Hydroxy-5-methylfuran-3(2H)-one-d₃ is deuterated labeled 2-Isopropyl-3-methoxypyrazine.

HY-126121S

*2-Hydroxy* Ibuprofen-d6** (±)-2-Hydroxy Ibuprofen-d<sub>6sub>	Isotope-Labeled Compounds COX	Inflammation/Immunology Cancer
2-Hydroxy Ibuprofen-d₆ is the deuterium labeled 2-Hydroxy Ibuprofen. 2-Hydroxy Ibuprofen is a metabolite of Ibuprofen. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively[1][2].

HY-G0003S1

*Iloperidone metabolite Hydroxy* Iloperidone-d3** P88-d<sub>3sub>; Hydroxy Iloperidone-d<sub>3sub>	Drug Metabolite	Others
Iloperidone metabolite Hydroxy Iloperidone-d₃ is the deuterium labeled Iloperidone metabolite Hydroxy Iloperidone[1].

HY-123371

Ro 07-1902	Others	Cancer
Ro 07-1902 is an effective antitumor potentiator that can significantly enhance the antitumor effect of CCNU against KHT sarcoma at low doses .

HY-156351S

cis-4-Nonenal-d2	Isotope-Labeled Compounds	Others
cis-4-Nonenal-d₂ is deuterated labeled cis-4-Nonenal.

HY-W744647

cis-4-Heptenal-D2	Isotope-Labeled Compounds	Others
cis-4-Heptenal-d₂ is deuterated labeled cis-4-Heptenal.

HY-10844S1

Pretomanid-d5 PA-824-d<sub>5sub>; (S)-PA 824-d<sub>5sub>	Antibiotic Bacterial Isotope-Labeled Compounds	Infection Cancer
Pretomanid-d₅ is deuterated labeled Pretomanid (HY-10844). Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 μg/mL.

HY-12773AS2

*5-Hydroxy* Propafenone-d6 hydrochloride** GPV-129-d<sub>6sub> hydrochloride	Isotope-Labeled Compounds	Others
5-Hydroxy Propafenone-d₆ hydrochloride is deuterated labeled 5-Hydroxy Propafenone.

HY-12772S

Hydroxy Itraconazole-d8 R-63373-d<sub>8sub>	Fungal	Others
Hydroxy Itraconazole-d₈ is the deuterium labeled Hydroxy Itraconazole. Hydroxy Itraconazole is an active metabolite of Itraconazole (ITZ), which is a triazole antifungal agent.

HY-W010305S

*5-Ethyl-3-hydroxy-4-methylfuran-2(5H)-one-d4* Ethyl Fenugreek Lactone-d<sub>4sub>	Isotope-Labeled Compounds	Others
5-Ethyl-3-hydroxy-4-methylfuran-2(5H)-one-d₄ is deuterated labeled 6-Heptyltetrahydro-2H-pyran-2-one.

HY-131543S

*22-Hydroxy* Mifepristone-d6** RU 42698-d<sub>6sub>	Isotope-Labeled Compounds	Others
22-Hydroxy Mifepristone-d₆ is the deuterium labeled 22-Hydroxy Mifepristone[1]. 22-Hydroxy Mifepristone-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W025101S

*Ethyl 3-hydroxy-3-methylbutanoate-d6* Ethyl 3-Hydroxy-3-methylbutyrate-d<sub>6sub>	Isotope-Labeled Compounds	Others
Ethyl 3-hydroxy-3-methylbutanoate-d₆ is the deuterium labeled Ethyl 3-hydroxy-3-methylbutanoate[1].

HY-111975S1

*7'-Hydroxy* ABA-d2** 7'-OH ABA-d<sub>2sub>	Isotope-Labeled Compounds	Others
7'-Hydroxy ABA-d₂2 is the deuterium labeled 7'-Hydroxy ABA[1].

HY-111975S5

*7'-Hydroxy* ABA-d7** 7'-OH ABA-d<sub>7sub>	Isotope-Labeled Compounds	Others
7'-Hydroxy ABA-d₇ is the deuterium labeled 7'-Hydroxy ABA[1].

HY-151930S

*8′-Hydroxy* ABA-d8** 8'-OH-ABA-d<sub>8sub>	Drug Metabolite	Others
8′-Hydroxy ABA-d₈ is the deuterium labeled 8’-Hydroxy ABA[1].

HY-151930S1

*8′-Hydroxy* ABA-d2** 8'-OH-ABA-d<sub>2sub>	Drug Metabolite	Others
8′-Hydroxy ABA-d₂ is the deuterium labeled 8’-Hydroxy ABA[1].

HY-108263S

*3-Hydroxy* Midostaurin-d5** CGP52421-d<sub>5sub>	Isotope-Labeled Compounds FLT3	Cancer
3-Hydroxy Midostaurin-d₅ is a deuterium labeled 3-Hydroxy Midostaurin. 3-Hydroxy Midostaurin is a metabolite of PKC412, which effectively inhibits FMS-like tyrosine kinase-3 (FLT3) autophosphorylation with IC50s of approximately 132 nM and 9.8 μM in culture medium and plasma, respectively[1].

HY-W008216S

HMMNI-d3 Hydroxy Dimetridazole-d<sub>3sub>	Drug Metabolite Isotope-Labeled Compounds	Infection
HMMNI-d₃ is deuterium labeled HMMNI. HMMNI (Hydroxy dimetridazole) is a hydroxy metabolite of Dimetridazole. Dimetridazole is a nitroimidazole class agent that combats protozoan infections[1].

HY-115608

cis-4P-PDOT	Biochemical Assay Reagents	Others
cis-4P-PDOT (compound 1a) is a 8-methoxy analog .

HY-B0151S

Pregnenolone-d4 3β-Hydroxy-5-pregnen-20-one-d<sub>4sub>	Cannabinoid Receptor TRP Channel Endogenous Metabolite Autophagy	Neurological Disease
Pregnenolone-d₄ is the deuterium labeled Pregnenolone. Pregnenolone (3β-Hydroxy-5-pregnen-20-one) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone can protect the brain from cannabis intoxication[1][2]. Pregnenolone is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels[3].

HY-121385S

Hydroxy Bosentan-d6 Ro 48-5033-d<sub>6sub>	Isotope-Labeled Compounds Endogenous Metabolite	Cardiovascular Disease
Hydroxy Bosentan-d₆ is deuterium labeled Hydroxy bosentan. Hydroxy bosentan (Ro 48-5033) is a primary metabolite of Bosentan (BOS) metabolized by the cytochrome P450 system in the liver. Ro 48-5033 assists BOS pharmacologically, retaining 10%-20% activities[1].

HY-113038AS1

α-Hydroxyglutaric acid-d4 disodium 2-Hydroxyglutarate-d<sub>4sub> disodium; 2-Hydroxyglutaric acid-d<sub>4sub> disodium; 2-Hydroxypentanedioic acid-d<sub>4sub> disodium	Histone Demethylase Endogenous Metabolite	Cancer
α-Hydroxyglutaric acid-d₄ (disodium) is the deuterium labeled α-Hydroxyglutaric acid disodium[1]. α-Hydroxyglutaric acid (2-Hydroxyglutarate) disodium is an α-hydroxy acid form of glutaric acid. α-Hydroxyglutaric acid disodium is a competitive inhibitor of multiple α-ketoglutarate-dependent dioxygenases, including histone demethylases and the TET family of 5-methlycytosine (5mC) hydroxylases[2].

HY-W354610S

*N-(4-Hydroxy-3-methoxybenzyl)stearamide-d3* N-Vanillyloctadecanamide-d<sub>3sub>	Isotope-Labeled Compounds	Others
N-(4-Hydroxy-3-methoxybenzyl)stearamide-d₃ is the deuterium labeled N-(4-hydroxy-3-methoxybenzyl)stearamide[1].

HY-41680S

4-Aminobenzonitrile-d4 4-Aminobenzonitrile-d<sub>4sub>; 4-Cyanoaniline-d<sub>4sub>; 4-Cyanobenzenamine-d<sub>4sub>	Isotope-Labeled Compounds	Others
4-Aminobenzonitrile-d₄ is the deuterium labeled 4-Aminobenzonitrile[1].

HY-66005S

Acetaminophen-d4 Paracetamol-d<sub>4sub>; 4-Acetamidophenol-d<sub>4sub>; 4'-Hydroxyacetanilide-d<sub>4sub>	COX Histone Acetyltransferase Endogenous Metabolite	Inflammation/Immunology
Acetaminophen-d₄ is the deuterium labeled Acetaminophen. Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM; is a widely used antipyretic and analgesic agent[1][2][3]. Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor[4].

HY-12773AS

*5-Hydroxy* Propafenone-d5 hydrochloride** GPV-129 D5 Hydrochloride; Lu 40-545 d<sub>5sub>	Isotope-Labeled Compounds	Cardiovascular Disease
5-Hydroxy Propafenone-d₅ (hydrochloride) is the deuterium labeled 5-Hydroxy Propafenone.

HY-B1159S

Nitroxoline-D4 8-Hydroxy-5-nitroquinoline-d<sub>4sub>; 5-Nitro-8-quinolinol-d<sub>4sub>	Bacterial Autophagy Antibiotic	Infection Cancer
Nitroxoline-d₄ is the deuterium labeled Nitroxoline. Nitroxoline is an antibiotic that has proven to be very effective at combating biofilm infections. Nitroxoline functions by chelating Fe2+ and Zn2+ ions from the biofilm matrix[1][2].

HY-W127518

cis-4-Decen-1-ol	Biochemical Assay Reagents	Others
cis-4-Decen-1-ol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W127532

cis-4-Hepten-1-ol	Biochemical Assay Reagents	Others
cis-4-Hepten-1-ol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W127617

cis-4-Hexen-1-ol	Biochemical Assay Reagents	Others
cis-4-Hexen-1-ol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-B0151S2

Pregnenolone-d4-1 3β-Hydroxy-5-pregnen-20-one-d<sub>4sub>-1	Cannabinoid Receptor TRP Channel Endogenous Metabolite Autophagy	Neurological Disease
Pregnenolone-d₄-1 is the deuterium labeled Pregnenolone. Pregnenolone (3β-Hydroxy-5-pregnen-20-one) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone can protect the brain from cannabis intoxication[1][2]. Pregnenolone is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels[3].

HY-118714S

*α-Hydroxy* alprazolam-d5** U 40125-d<sub>5sub>; alpha-Hydroxyalprazolam-d<sub>5sub>	Isotope-Labeled Compounds	Others
α-Hydroxy alprazolam-d₅ (U 40125-d₅; alpha-Hydroxyalprazolam-d₅) is the deuterium labled α-hydroxy alprazolam (HY-118714).

HY-Y0755

*N-Boc-4-hydroxy-L-proline methyl ester*	ADC Linker PROTAC Linkers	Cancer
N-Boc-cis-4-hydroxy-L-proline methyl ester is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Boc-cis-4-hydroxy-L-proline methyl ester is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[2

HY-110189S1

Pregnenolone monosulfate-d4 sodium 3β-Hydroxy-5-pregnen-20-one monosulfate-d<sub>4sub> sodium	Isotope-Labeled Compounds Cannabinoid Receptor TRP Channel Endogenous Metabolite Autophagy	Neurological Disease
Pregnenolone monosulfate-d₄ (sodium) is the deuterium labeled Pregnenolone monosulfate. Pregnenolone monosulfate sodium (3β-Hydroxy-5-pregnen-20-one monosulfate sodium) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone monosulfate sodium acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone monosulfate sodium can protect the brain from cannabis intoxication[1][2]. Pregnenolone monosulfate sodium is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels[3].

HY-Y1042S

4-Cyanophenol-d4 4-Hydroxybenzonitrile-d<sub>4sub>; 4-Hydroxycyanobenzene-d<sub>4sub>; NSC 400524-d<sub>4sub>	Isotope-Labeled Compounds	Others
4-Cyanophenol-d₄ is the deuterium labeled 4-Cyanophenol[1].

HY-17461S3

Cortisone-d2 17-Hydroxy-11-dehydrocorticosterone-d<sub>2sub>; Kendall's compound E-d<sub>2sub>	Isotope-Labeled Compounds Glucocorticoid Receptor Endogenous Metabolite	Endocrinology
Cortisone-d₂ is the deuterium labeled Cortisone. Cortisone (17-Hydroxy-11-dehydrocorticosterone), an oxidized metabolite of Cortisol (a Glucocorticoid). Cortisone acts as an immunosuppressant and anti-inflammatory agent. Cortisone can partially intervene in binding of Glucocorticoid to Glucocorticoid-receptor at high concentrations[1][3][4][5].

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-40136

cis-4-Hydroxy-L-proline	Structural Classification Microorganisms Classification of Application Fields Santalum album Linn. Ketones, Aldehydes, Acids Source classification Metabolic Disease Plants Endogenous metabolite Disease Research Fields Santalaceae	Endogenous Metabolite
cis-4-Hydroxy-L-proline, a proline analogue, is an inhibitor of collagen production. cis-4-Hydroxy-L-proline could inhibit fibroblast growth by preventing the deposition of triple-helical collagen on the cell layer. cis-4-Hydroxy-L-proline also depresses the growth of primary N-nitrosomethylurea-induced rat mammary tumors ^[4].

HY-125833

Alpha-Naphthoflavone 5+ Cited Publications	Flavonoids Flavones Source classification Indigofera heterantha Wall. ex Brand. Plants Compositae Disease Research Fields Cancer	Cytochrome P450 Aryl Hydrocarbon Receptor Apoptosis
Alpha-Naphthoflavone is an orally active flavonoid that is a potent, competitive inhibitor of aromatase< b>aromatase. < b > IC < sub > 50 < / sub > < / b > and < b > K < sub > I < / sub > < / b > value were 0.5 and 0.2 microns. Alpha-Naphthoflavone can inhibit cell proliferation and induce apoptosis ^[4].

HY-W008129

*H-D-cis-Hyp-OH*	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
cis-4-Hydroxy-D-proline is a precursor of conformationally restricted PNA adenine monomer. cis-4-Hydroxy-D-proline can be used to study the specificity and kinetics of D-alanine dehydrogenase .

HY-W011474

Geranylgeraniol	Structural Classification Natural Products Microorganisms	NF-κB
Geranylgeraniol is an orally acitve vitamin K₂ sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model ^[4].

HY-N9241

*3-Hydroxy-7-methoxyflavone*	Structural Classification Flavonols Flavonoids Labiatae Source classification Gymnaster koraiensis Plants	Others
3-Hydroxy-7-methoxyflavone (compound 1) is a flavonoid. 3-Hydroxy-7-methoxyflavone is isolated from natural Salvia elegans. 3-Hydroxy-7-methoxyflavone has anti-anxiety effect .

HY-40136R

cis-4-Hydroxy-L-proline (Standard)	Structural Classification Microorganisms Santalum album Linn. Ketones, Aldehydes, Acids Source classification Plants Endogenous metabolite Santalaceae	Endogenous Metabolite
cis-4-Hydroxy-L-proline (Standard) is the analytical standard of cis-4-Hydroxy-L-proline. This product is intended for research and analytical applications. cis-4-Hydroxy-L-proline, a proline analogue, is an inhibitor of collagen production. cis-4-Hydroxy-L-proline could inhibit fibroblast growth by preventing the deposition of triple-helical collagen on the cell layer. cis-4-Hydroxy-L-proline also depresses the growth of primary N-nitrosomethylurea-induced rat mammary tumors ^[3][4].

HY-N0351A

cis-p-Coumaric acid cis-4-Hydroxycinnamic acid	Structural Classification Arachis hypogaea L. Leguminosae Source classification Coumarins Phenylpropanoids Plants	Apoptosis
cis-p-Coumaric acid (cis-4-Hydroxycinnamic acid) is the cis-form of p-Coumaric acid (HY-N0351), which is higher in viable seeds of groundnuts than in non-viable ones. p-Coumaric acid is an isomer of cinnamic acid with oral activity. p-Coumaric acid inhibits cell proliferation and promotes Apoptosis .

HY-N11799

Neochilenin 3-O-Methylquercetin 4′-O-glucoside	Structural Classification Flavonoids Source classification Plants Compositae Other Flavonoids	Others
Neochilenin (3-O-Methylquercetin 4 '-O-glucoside) is a glycoside of 3-O-methylquercetin, which can be isolated from the sub-family Cereoideae (Cactaceae). .

HY-N9012

*2-Hydroxy-5-(2-hydroxy-4-methoxybenzyl)-4-methoxybenzaldehyde*	Structural Classification Source classification Phenols Dalbergia congesta Graham ex Wight & Arn. Plants Fabaceae	Others
2-Hydroxy-5-(2-hydroxy-4-methoxybenzyl)-4-methoxybenzaldehyde is a Phenols product that can be isolated from the roots of Dalbergia congesta .

HY-N9224

*5-Acetyl-6-hydroxy-2-(1-hydroxy-1-methylethyl)benzofuran*	Structural Classification Monophenols Source classification Artemisia dracunculus L. Phenols Plants Compositae	Others
5-Acetyl-6-hydroxy-2-(1-hydroxy-1-methylethyl)benzofuran is a Phenols product that can be isolated from the herbs of Artemisia dracunculus. .

HY-116688

*2-Hydroxy-4-(methylthio)butyric acid*	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Others
2-Hydroxy-4-(methylthio)butyric acid is a dietary essential amino acid which is converted to Methionine (HY-13694) by 2-hydroxy acid dehydrogenase and 2-hydroxy acid oxidase. 2-Hydroxy-4-(methylthio)butyric acid is promising for research of gut disease .

HY-N2674

*5-Hydroxy-1-methoxyxanthone* 5-Hydroxy-1-methoxyxanthen-9-one	Structural Classification Flavonoids Hypericum brasiliense Choisy Source classification Hypericaceae Plants Other Flavonoids	Others
5-Hydroxy-1-methoxyxanthone (5-Hydroxy-1-methoxyxanthen-9-one) is a Iridoids product that can be isolated from the roots of Lamiophlomis rotata (Benth.) Kudo .

HY-135212R

Hydroxy ipronidazole (Standard)	Structural Classification Natural Products Source classification Endogenous metabolite	Endogenous Metabolite
Hydroxy ipronidazole (Standard) is the analytical standard of Hydroxy ipronidazole. This product is intended for research and analytical applications. Hydroxy ipronidazole (Ipronidazole-OH) is a metabolite of nitroimidazole antibiotics, such as ipronidazole (IPZ). Hydroxy ipronidazole may has similar mutagenic potential as the parent compound .

HY-126121R

*2-Hydroxy* Ibuprofen (Standard)**	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	COX
2-Hydroxy Ibuprofen (Standard) is the analytical standard of 2-Hydroxy Ibuprofen. This product is intended for research and analytical applications. 2-Hydroxy Ibuprofen is a metabolite of Ibuprofen. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively.

HY-W010254

*4′-Hydroxy-2′-methylacetophenone*	Infection Structural Classification Monophenols Epiphyllum oxypetalum (DC.) Haw. Cactaceae Classification of Application Fields Ketones, Aldehydes, Acids Source classification Phenols Plants Disease Research Fields	Parasite
4′-Hydroxy-2′-methylacetophenone, an aroma compound of red wines, is isolated from cv. Bobal grape variety. 4′-Hydroxy-2′-methylacetophenone has ciliate toxicity. 4′-Hydroxy-2′-methylacetophenone inhibits the growth of T. pyriformis, with an IC₅₀ of 0.65 mM .

HY-N8047

*5-Hydroxy-7-(4'-hydroxy-3'-methoxyphenyl)-1-phenyl-3-heptanone*	Structural Classification Source classification Phenols Plants Curcuma longa Zingiberaceae	Others
5-Hydroxy-7-(4'-hydroxy-3'-methoxyphenyl)-1-phenyl-3-heptanone is a Phenols product that can be isolated from the rhizomes of Curcuma longa L. .

HY-N13284

*13-Hydroxy-9-octadecenoic acid*	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Fungal
13-Hydroxy-9-octadecenoic acid is a hydroxy unsaturated fatty acid (HUFA) that has anti-fungal activity .

HY-N7602

*10-Hydroxy* majoroside**	Plantaginaceae Natural Products Classification of Application Fields Source classification Other Diseases Plantago asiatica L. Plants Disease Research Fields	Others
10-Hydroxy majoroside is a methanol extract isolated from plantago asiatica .

HY-N0445

*2-Hydroxy-4-methoxybenzaldehyde*	Structural Classification Monophenols other families Classification of Application Fields Simple Phenylpropanols Source classification Other Diseases Phenols Phenylpropanoids Plants Disease Research Fields	Tyrosinase Bacterial
2-hydroxy-4-methoxybenzaldehyde is a potent tyrosinase inhibitor . 2-Hydroxy-4-methoxybenzaldehyde, an isomer of Vanillin, could be used to synthesis Urolithin M7

HY-W001663

*4'-Hydroxy-3'-methylacetophenone*	Infection Monophenols Classification of Application Fields Ketones, Aldehydes, Acids Source classification Rubiaceae Phenols Plants Disease Research Fields Coffea arabica L.	Bacterial
4'-Hydroxy-3'-methylacetophenone, a phenolic volatile compound, is isolated from Hawaiian green coffee beans (Coffea Arabica L.). 4'-Hydroxy-3'-methylacetophenone has potent antioxidant activities. 4'-Hydroxy-3'-methylacetophenone also can be used to synthesize heterocyclic compounds which have antimycobacterial activity .

HY-N8797

*Methyl 1-hydroxy-4-oxocyclohexaneacetate*	Structural Classification Erinacea anthyllis Link Ketones, Aldehydes, Acids Source classification Plants Compositae	Others
Methyl 1-hydroxy-4-oxocyclohexaneacetate (Compound 7) is a lactone. Methyl 1-hydroxy-4-oxocyclohexaneacetate is isolated from the natural Senecio scandens. Methyl 1-hydroxy-4-oxocyclohexaneacetate has anti-inflammatory andantibacterialactivity .

HY-126121

*2-Hydroxy* Ibuprofen** (±)-2-Hydroxy Ibuprofen	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields Inflammation/Immunology	COX
2-Hydroxy Ibuprofen is a metabolite of Ibuprofen. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC₅₀s of 13 μM and 370 μM, respectively.

HY-N7971

*2-Hydroxy-1-Methoxyaporphine*	Cardiovascular Disease Alkaloids Structural Classification Monophenols Classification of Application Fields Source classification Phenols Nelumbo nucifera Gaertn. Plants Isoquinoline Alkaloids Disease Research Fields Nymphaeaceae	Endogenous Metabolite
2-Hydroxy-1-Methoxyaporphine is an alkaloid that can be isolated from Nelumbo nucifera. 2-Hydroxy-1-Methoxyaporphine is the major active ingredient of the Chinese traditional medicine Jiang-Zhi-Ning .

HY-135212

Hydroxy ipronidazole	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Hydroxy ipronidazole (Ipronidazole-OH) is a metabolite of nitroimidazole antibiotics, such as ipronidazole (IPZ). Hydroxy ipronidazole may has similar mutagenic potential as the parent compound .

HY-W016103

*1-Hydroxy-2-naphthoic acid*	Structural Classification Monophenols Classification of Application Fields Ketones, Aldehydes, Acids Source classification Phenols Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
1-Hydroxy-2-naphthoic acid is an endogenous metabolite.

HY-23195

*Potassium 2-hydroxy-2-methylsuccinate*	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Potassium 2-hydroxy-2-methylsuccinate is an endogenous metabolite.

HY-W007888

*2-Hydroxy-4-methylbenzaldehyde*	Structural Classification Monophenols Classification of Application Fields Ketones, Aldehydes, Acids Source classification Phenols Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
2-Hydroxy-4-methylbenzaldehyde is an endogenous metabolite.

HY-W008188

*3-Hydroxy-4-aminopyridine*	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
3-Hydroxy-4-aminopyridine is an endogenous metabolite.

HY-N7608

Beiwutine 10-Hydroxy mesaconitine	Alkaloids Terpenoids Source classification Ranunculaceae Diterpenoids Aconitum carmichaeli Debx. Plants	Others
Beiwutine (10-Hydroxy mesaconitine) is a diester diterpenoid alkaloid .

HY-N13543

*5-Hydroxy-7-(4-hydroxy-3-methoxyphenyl)-1-phenylhept-4-en-3-one*	Zingiber officinale Roscoe Structural Classification Source classification Phenols Polyphenols Plants Zingiberaceae	Others
5-Hydroxy-7-(4-hydroxy-3-methoxyphenyl)-1-phenylhept-4-en-3-one is a natural product .

HY-75625

*2-Hydroxy-4-methoxybenzoic acid* 4-Methoxysalicylic Acid	Monophenols other families Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Phenols Plants Disease Research Fields	Others
2-Hydroxy-4-methoxybenzoic acid is a derivative of methoxybenzoic. 2-Hydroxy-4-methoxybenzoic is a potential biomarker.

HY-N3505

*14-Hydroxy* sprengerinin C**	Classification of Application Fields Dipsacaceae Source classification Other Diseases Plants Dipsacus asper Disease Research Fields Steroids	Others
14-Hydroxy sprengerinin C is a steroidal compound found in Ophiopogon japonicus.

HY-N13416

*6-Hydroxy-7-methoxydihydroligustilide*	Structural Classification Natural Products Source classification Umbelliferae Plants Echinacea angustifolia DC.	Others
6-Hydroxy-7-methoxydihydroligustilide is a natural product .

HY-138545

*4-Hydroxy-6-methylcoumarin*	Structural Classification Ekebergia senegalensis Source classification Coumarins Phenylpropanoids Plants Meliaceae	Others
4-Hydroxy-6-methylcoumarin is a Coumarin product .

HY-N8142

*6-Hydroxy-2-phenethylchromone*	Monophenols other families Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Phenols Plants Disease Research Fields	Others
6-Hydroxy-2-phenethylchromone possesses antioxidant activity .

HY-P2274

Argifin	Infection Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields	Parasite
Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms, with IC₅₀s of 0.025 μM, 6.4 μM , 1.1 μM and 4.5 μM for SmChiA (Serratia marcescens chitinaese A), SmChiB, Aspergillus fumigatus chitinase B1 and human chitotriosidase, respectively .

HY-22167

*Methyl 2-hydroxy-4-methylvalerate*	Structural Classification Natural Products Animals Classification of Application Fields Source classification Other Diseases Disease Research Fields	Others
Methyl 2-hydroxy-4-methylvalerate is one of dominant volatile compounds in Zhenjiang aromatic vinegar. Methyl 2-hydroxy-4-methylvalerate is used for charting flavour biosynthesis networks of vinegar microbiota .

HY-N8680

*12-Hydroxy-2,3-dihydroeuparin*	Structural Classification Classification of Application Fields Ophryosporus axilliflorus Hieron. Source classification Phenols Plants Compositae Inflammation/Immunology Disease Research Fields	Others
12-Hydroxy-2,3-dihydroeuparin (compound 7) is a natural product that can be isolated from the aerial parts of Ophryosporus axilliflorus. 12-Hydroxy-2,3-dihydroeuparin shows extremely anti-inflammatory activity .

HY-N9735

*8-Hydroxy-9,10-diisobutyryloxythymol*	Structural Classification Monophenols Source classification Euchresta horsfieldii (Lesch.) J. Benn. Phenols Plants Compositae	Bacterial
8-Hydroxy-9,10-diisobutyryloxythymol is a natural monoterpenoid with antibacterial properties. 8-Hydroxy-9,10-diisobutyryloxythymol against S. aureus, S. flexneri, and S. paratyphi-B with MIC values of 6.25 μg/mL .

HY-N8114

*2-Naphthalenecarboxylic acid, 4-(D-glucopyranosyloxy)-1-hydroxy-3-(3-hydroxy-3-methylbutyl)-, methyl ester*	Quinones Monophenols Classification of Application Fields Source classification Other Diseases Rubiaceae Phenols Plants Naphthalene Quinones Disease Research Fields Rubia cordifolia L.	Others
2-Naphthalenecarboxylic acid, 4-(D-glucopyranosyloxy)-1-hydroxy-3-(3-hydroxy-3-methylbutyl)-, methyl ester (compound 3) is a natural product that can be isolated from the dried roots of Rubia cordifolia .

HY-W002587

*4-Hydroxy-3-methylbenzoic acid*	Monophenols Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Phenols Endogenous metabolite Disease Research Fields	Endogenous Metabolite
4-Hydroxy-3-methylbenzoic acid is a normal organic acid identified in urine specimens from a healthy population.

HY-N1625

*1-Hydroxy-2-methylanthraquinone*	Quinones Monophenols Classification of Application Fields Anthraquinones Source classification Rubiaceae Morinda citrifolia Linn. Phenols Plants Disease Research Fields Inflammation/Immunology	Bacterial
1-Hydroxy-2-methylanthraquinone exhibits antimicrobial, antioxidant, pesticidal, and anti-inflammatory activities .

HY-N10192

Aculene D	Infection Microorganisms Classification of Application Fields Terpenoids Sesquiterpenes Source classification Disease Research Fields	Endogenous Metabolite Bacterial
Aculene D, a fungal metabolite, shows quorum sensing (QS) inhibitory activity against Chromobacterium violaceum CV026, and could significantly reduce violacein production in N-hexanoyl-l-homoserine lactone (C6-HSL) induced C. violaceum CV026 cultures at sub-inhibitory concentrations .

HY-W011474R

Geranylgeraniol (Standard)	Structural Classification Natural Products Microorganisms	NF-κB
Geranylgeraniol (Standard) is the analytical standard of Geranylgeraniol. This product is intended for research and analytical applications. Geranylgeraniol is an orally acitve vitamin K2 sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model ^[3][4].

HY-N3287

*Methyl 3-hydroxy-4,5-dimethoxybenzoate*	Infection Monophenols Classification of Application Fields Source classification Phenols Euphorbiaceae Plants Disease Research Fields Macaranga sinensis (Baill.) Muell. Arg.	Bacterial
Methyl 3-hydroxy-4,5-dimethoxybenzoate is a gallic acid derivant isolated from myricaria Laxiflora. Methyl 3-hydroxy-4,5-dimethoxybenzoate shows obvious antimicrobial activities. Methyl 3-hydroxy-4,5-dimethoxybenzoate shows fairly active for oxidation resistance in the presence of H₂O₂ .

HY-N13673

*2-Hydroxy-1,8-dimethoxyxanthone*	Structural Classification Xanthones Calophyllum membranaceum Gardner & Champ. Source classification Phenols Plants Calophyllaceae	Others
2-Hydroxy-1,8-dimethoxyxanthone is a natural product .

HY-N12004

*19-Hydroxy-10-deacetylbaccatin III*	Structural Classification Terpenoids Source classification Taxaceae Diterpenoids Plants Taxus chinensis (Pilger) Rehd.	Others
19-Hydroxy-10-deacetylbaccatin III (compound 13) is a taxane with potential antitumor activity. 19-Hydroxy-10-deacetylbaccatin III has weak cytotoxicity against A498 and NCI-H226 cell lines. The study found that the inhibition rates of 30 μg/mL 19-Hydroxy-10-deacetylbaccatin III on A498, NCI-H226 and PC-3 were 16.6% and 32% respectively .

HY-W002339

*3-Hydroxy-2-methylpyridine*	Alkaloids other families Classification of Application Fields Leguminosae Source classification Other Diseases Pyridine Alkaloids Astragalus membranaceus var. mongholicus (Bunge)P.K.Hsiao Plants Disease Research Fields	DNA/RNA Synthesis
3-Hydroxy-2-methylpyridine, isolated from alkaline extracts of cocoa, is used in the synthesis of pyrimidine .

HY-W005327

*1-Hydroxy-2-butanone*	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Bacterial Endogenous Metabolite
1-Hydroxy-2-butanone is a natural compound isolated from Bomboo Juice with antitubercular activity .

HY-N7179

*7-Hydroxy-5-methoxycoumarin*	Source classification Coumarins Phenylpropanoids Plants Convolvulaceae Ipomoea batatas (Linn.) Lamarck	Others
7-Hydroxy-5-methoxycoumarin is a phloroglucinol-type furocoumarins, a potent naturally-occurring insect antifeedant .

Cat. No.	Product Name	Chemical Structure

HY-143979S

1-(2-Chloroethyl)-3-((1R,4R)-4-hydroxycyclohexyl)-1-nitrosourea-d4
trans-4’-Hydroxy CCNU Lomustine-d₄ is the deuterium labeled trans-4’-Hydroxy CCNU Lomustine[1].

HY-40136S

cis-4-Hydroxy-L-proline-d3

cis-4-Hydroxy-L-proline-d₃ is the deuterium labeled cis-4-Hydroxy-L-proline. cis-4-Hydroxy-L-proline, a proline analogue, is an inhibitor of collagen production. cis-4-Hydroxy-L-proline could inhibit fibroblast growth by preventing the deposition of triple-helical collagen on the cell layer. cis-4-Hydroxy-L-proline also depresses the growth of primary N-nitrosomethylurea-induced rat mammary tumors[1][2][3][4].

HY-143978S

cis-4’-Hydroxy CCNU Lomustine-d4
cis-4’-Hydroxy CCNU Lomustine-d₄ is the deuterium labeled cis-4’-Hydroxy CCNU Lomustine[1].

HY-121385S1

Hydroxy Bosentan-d4
Hydroxy Bosentan-d₄ is deuterium labeled Hydroxy bosentan. Hydroxy bosentan (Ro 48-5033) is a primary metabolite of Bosentan (BOS) metabolized by the cytochrome P450 system in the liver. Ro 48-5033 assists BOS pharmacologically, retaining 10%-20% activities[1].

HY-115354S

*4-Hydroxy* Alprazolam-d5**
4-Hydroxy Alprazolam-d5 (4-Hydroxyalprazolam-d5; RS-4-Hydroxyalprazolam-d5) is the deuterium labeled 4-hydroxy Alprazolam (HY-115354) .

HY-W012927S

*4-Hydroxy-5-methylfuran-3(2H)-one-d3*
4-Hydroxy-5-methylfuran-3(2H)-one-d₃ is deuterated labeled 2-Isopropyl-3-methoxypyrazine.

HY-126121S

*2-Hydroxy* Ibuprofen-d6**
2-Hydroxy Ibuprofen-d₆ is the deuterium labeled 2-Hydroxy Ibuprofen. 2-Hydroxy Ibuprofen is a metabolite of Ibuprofen. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively[1][2].

HY-G0003S1

*Iloperidone metabolite Hydroxy* Iloperidone-d3**
Iloperidone metabolite Hydroxy Iloperidone-d₃ is the deuterium labeled Iloperidone metabolite Hydroxy Iloperidone[1].

HY-156351S

cis-4-Nonenal-d2
cis-4-Nonenal-d₂ is deuterated labeled cis-4-Nonenal.

HY-W744647

cis-4-Heptenal-D2
cis-4-Heptenal-d₂ is deuterated labeled cis-4-Heptenal.

HY-10844S1

Pretomanid-d5
Pretomanid-d₅ is deuterated labeled Pretomanid (HY-10844). Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 μg/mL.

HY-12773AS2

*5-Hydroxy* Propafenone-d6 hydrochloride**
5-Hydroxy Propafenone-d₆ hydrochloride is deuterated labeled 5-Hydroxy Propafenone.

HY-12772S

Hydroxy Itraconazole-d8
Hydroxy Itraconazole-d₈ is the deuterium labeled Hydroxy Itraconazole. Hydroxy Itraconazole is an active metabolite of Itraconazole (ITZ), which is a triazole antifungal agent.

HY-W010305S

*5-Ethyl-3-hydroxy-4-methylfuran-2(5H)-one-d4*
5-Ethyl-3-hydroxy-4-methylfuran-2(5H)-one-d₄ is deuterated labeled 6-Heptyltetrahydro-2H-pyran-2-one.

HY-131543S

*22-Hydroxy* Mifepristone-d6**
22-Hydroxy Mifepristone-d₆ is the deuterium labeled 22-Hydroxy Mifepristone[1]. 22-Hydroxy Mifepristone-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W025101S

*Ethyl 3-hydroxy-3-methylbutanoate-d6*
Ethyl 3-hydroxy-3-methylbutanoate-d₆ is the deuterium labeled Ethyl 3-hydroxy-3-methylbutanoate[1].

HY-111975S1

*7'-Hydroxy* ABA-d2**
7'-Hydroxy ABA-d₂2 is the deuterium labeled 7'-Hydroxy ABA[1].

HY-111975S5

*7'-Hydroxy* ABA-d7**
7'-Hydroxy ABA-d₇ is the deuterium labeled 7'-Hydroxy ABA[1].

HY-151930S

*8′-Hydroxy* ABA-d8**
8′-Hydroxy ABA-d₈ is the deuterium labeled 8’-Hydroxy ABA[1].

HY-151930S1

*8′-Hydroxy* ABA-d2**
8′-Hydroxy ABA-d₂ is the deuterium labeled 8’-Hydroxy ABA[1].

HY-108263S

*3-Hydroxy* Midostaurin-d5**
3-Hydroxy Midostaurin-d₅ is a deuterium labeled 3-Hydroxy Midostaurin. 3-Hydroxy Midostaurin is a metabolite of PKC412, which effectively inhibits FMS-like tyrosine kinase-3 (FLT3) autophosphorylation with IC50s of approximately 132 nM and 9.8 μM in culture medium and plasma, respectively[1].

HY-W008216S

HMMNI-d3
HMMNI-d₃ is deuterium labeled HMMNI. HMMNI (Hydroxy dimetridazole) is a hydroxy metabolite of Dimetridazole. Dimetridazole is a nitroimidazole class agent that combats protozoan infections[1].

HY-B0151S

Pregnenolone-d4

Pregnenolone-d₄ is the deuterium labeled Pregnenolone. Pregnenolone (3β-Hydroxy-5-pregnen-20-one) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone can protect the brain from cannabis intoxication[1][2]. Pregnenolone is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels[3].

HY-121385S

Hydroxy Bosentan-d6
Hydroxy Bosentan-d₆ is deuterium labeled Hydroxy bosentan. Hydroxy bosentan (Ro 48-5033) is a primary metabolite of Bosentan (BOS) metabolized by the cytochrome P450 system in the liver. Ro 48-5033 assists BOS pharmacologically, retaining 10%-20% activities[1].

HY-113038AS1

α-Hydroxyglutaric acid-d4 disodium

α-Hydroxyglutaric acid-d₄ (disodium) is the deuterium labeled α-Hydroxyglutaric acid disodium[1]. α-Hydroxyglutaric acid (2-Hydroxyglutarate) disodium is an α-hydroxy acid form of glutaric acid. α-Hydroxyglutaric acid disodium is a competitive inhibitor of multiple α-ketoglutarate-dependent dioxygenases, including histone demethylases and the TET family of 5-methlycytosine (5mC) hydroxylases[2].

HY-W354610S

*N-(4-Hydroxy-3-methoxybenzyl)stearamide-d3*
N-(4-Hydroxy-3-methoxybenzyl)stearamide-d₃ is the deuterium labeled N-(4-hydroxy-3-methoxybenzyl)stearamide[1].

HY-41680S

4-Aminobenzonitrile-d4
4-Aminobenzonitrile-d₄ is the deuterium labeled 4-Aminobenzonitrile[1].

HY-66005S

Acetaminophen-d4
Acetaminophen-d₄ is the deuterium labeled Acetaminophen. Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM; is a widely used antipyretic and analgesic agent[1][2][3]. Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor[4].

HY-12773AS

*5-Hydroxy* Propafenone-d5 hydrochloride**
5-Hydroxy Propafenone-d₅ (hydrochloride) is the deuterium labeled 5-Hydroxy Propafenone.

HY-B1159S

Nitroxoline-D4
Nitroxoline-d₄ is the deuterium labeled Nitroxoline. Nitroxoline is an antibiotic that has proven to be very effective at combating biofilm infections. Nitroxoline functions by chelating Fe2+ and Zn2+ ions from the biofilm matrix[1][2].

HY-B0151S2

Pregnenolone-d4-1

Pregnenolone-d₄-1 is the deuterium labeled Pregnenolone. Pregnenolone (3β-Hydroxy-5-pregnen-20-one) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone can protect the brain from cannabis intoxication[1][2]. Pregnenolone is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels[3].

HY-118714S

*α-Hydroxy* alprazolam-d5**
α-Hydroxy alprazolam-d₅ (U 40125-d₅; alpha-Hydroxyalprazolam-d₅) is the deuterium labled α-hydroxy alprazolam (HY-118714).

HY-110189S1

Pregnenolone monosulfate-d4 sodium

Pregnenolone monosulfate-d₄ (sodium) is the deuterium labeled Pregnenolone monosulfate. Pregnenolone monosulfate sodium (3β-Hydroxy-5-pregnen-20-one monosulfate sodium) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone monosulfate sodium acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone monosulfate sodium can protect the brain from cannabis intoxication[1][2]. Pregnenolone monosulfate sodium is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels[3].

HY-Y1042S

4-Cyanophenol-d4
4-Cyanophenol-d₄ is the deuterium labeled 4-Cyanophenol[1].

HY-17461S3

Cortisone-d2
Cortisone-d₂ is the deuterium labeled Cortisone. Cortisone (17-Hydroxy-11-dehydrocorticosterone), an oxidized metabolite of Cortisol (a Glucocorticoid). Cortisone acts as an immunosuppressant and anti-inflammatory agent. Cortisone can partially intervene in binding of Glucocorticoid to Glucocorticoid-receptor at high concentrations[1][3][4][5].

HY-100634SA

4-Hydroxypropranolol-d7

4-Hydroxypropranolol-d₇ is the deuterium labeled 4-Hydroxypropranolol hydrochloride. 4-Hydroxypropranolol hydrochlorid is an active metabolite of Propranolol. 4-Hydroxypropranolol hydrochlorid is of comparable potency to Propranolol. 4-Hydroxypropranolol hydrochlorid inhibits β1- and β2-adrenergic receptors with pA2 values of 8.24 and 8.26, respectively. 4-Hydroxypropranolol hydrochlorid has intrinsic sympathomimetic activity, membrane stabilizing activity and potent antioxidant properties[1][2][3].

HY-17413S2

Zidovudine-d4
Zidovudine-d₄ is deuterated labeled Zidovudine (HY-17413). Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection. Zidovudine increases CRISPR/Cas9-mediated editing frequency.

HY-32351AS

Calcifediol-d6 monohydrate
Calcifediol-d₆ monohydrate is the deuterium labeled Calcifediol monohydrate. Calcifediol monohydrate (25-hydroxy Vitamin D3 monohydrate), is an effective VDR ligand and VD supplement. Calcifediol is a prohormone of the vitamin D endocrine system (VDES) and is hydroxylated in the liver to produce the active form, calcitriol. Calcifediol can rapidly increase serum VD levels .

HY-N0006S1

Demethoxycurcumin-d4
Demethoxycurcumin-d₄ is the deuterium labeled Demethoxycurcumin. Demethoxycurcumin (Curcumin II) is a major active curcuminoid; possess anti-inflammatory properties[1].

HY-100048S

Acetylisoniazid-d4
Acetylisoniazid-d₄ is the deuterium labeled Acetylisoniazid[1].

HY-118861S

Enclomiphene-d4 hydrochloride
Enclomiphene-d₄ (hydrochloride) is a deuterium labeled Enclomiphene. Enclomiphene-d₄ (hydrochloride) is a potent and orally active oestrogen receptor antagonist, with antioestrogenic property[1].

HY-109015S

Tucidinostat-d4
Tucidinostat-d₄ is the deuterium labeled Tucidinostat. Tucidinostat is a potent and orally bioavailable HDAC enzymes class I (HDAC1/2/3) and class IIb (HDAC10) inhibitor, with IC50s of 95, 160, 67 and 78 nM, respectively[1].

HY-19696AS

Tauroursodeoxycholate-d4 sodium
Tauroursodeoxycholate-d₄ (sodium) is the deuterium labeled Tauroursodeoxycholate sodium. Tauroursodeoxycholate (Tauroursodeoxycholic acid; TUDCA) sodium is an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12. Tauroursodeoxycholate also inhibits ERK.

HY-19696S1

Tauroursodeoxycholate-d4
Tauroursodeoxycholate-d₄ is deuterium labeled Tauroursodeoxycholate. Tauroursodeoxycholate (Tauroursodeoxycholic acid) is an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12. Tauroursodeoxycholate also inhibits ERK.

HY-B0389S24

D-Glucose-d4
D-Glucose-d₄ is the deuterium labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molec

HY-B0696AS

Tiagabine-d4 hydrochloride
Tiagabine-d₄ hydrochloride is deuterated labeled Tiagabine hydrochloride (HY-B0696A). Tiagabine hydrochloride is a potent and selective GABA reuptake inhibitor, used as an anticonvulsant agent, with IC₅₀s of 67, 446 and 182 nM for [ ³H]GABA uptake in Synaptosomes, Neurons and Glia, respectively .

HY-13273S

Ostarine-d4
Ostarine-d4 is a deuterated labeled Ostarine .

HY-34498S

4-Chloro-2-methylphenol-d4
4-Chloro-2-methylphenol-d₄ is the deuterium labeled 4-Chloro-2-methylphenol[1].

HY-10581AS1

Gatifloxacin-d4 hydrochloride
Gatifloxacin-d₄ (AM-1155-d₄; BMS-206584-d₄; PD135432-d₄) hydrochloride is deuterium-labeled Gatifloxacin (hydrochloride) (HY-10581A) .

HY-107542S

Oleoylethanolamide-d4
Oleoylethanolamide-d₄ is the deuterium labeled Oleoylethanolamide. Oleoylethanolamide is a high affinity endogenous PPAR-α agonist, which plays an important role in the treatment of obesity and arteriosclerosis.

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks