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NSC 1940-d<sub>4</sub>

" in MedChemExpress (MCE) Product Catalog:

By Targets:	P-glycoprotein (13) 11β-HSD (3) 5 alpha Reductase (4) 5-HT Receptor (67) Acetolactate Synthase (ALS) (1) Acyltransferase (1) ADC Cytotoxin (13) ADC Linker (1) Adenosine Kinase (1) Adenosine Receptor (9) Adrenergic Receptor (81) AIM2 (1) Akt (13) Aldehyde Dehydrogenase (ALDH) (1) Amino Acid Derivatives (11) Aminopeptidase (2) AMPK (10) Amyloid-β (6) Anaplastic lymphoma kinase (ALK) (8) Androgen Receptor (18) Angiotensin Receptor (22) Angiotensin-converting Enzyme (ACE) (14) Antibiotic (185) Antifolate (9) Apical Sodium-Dependent Bile Acid Transporter (2) Apoptosis (321) Arp2/3 Complex (1) Aryl Hydrocarbon Receptor (6) Atg4 (1) ATM/ATR (1) ATP Citrate Lyase (2) ATP Synthase (2) Aurora Kinase (1) Autophagy (302) Bacterial (271) Bcl-2 Family (7) Bcr-Abl (12) BCRP (3) Beta-lactamase (1) Beta-secretase (1) Biochemical Assay Reagents (16) Btk (4) c-Fms (2) c-Kit (15) c-Met/HGFR (5) c-Myc (2) Calcineurin (2) Calcium Channel (67) Cannabinoid Receptor (10) Carbonic Anhydrase (9) Casein Kinase (2) Caspase (5) CaSR (2) Cathepsin (1) CCR (2) CD73 (1) CDK (18) CFTR (5) Checkpoint Kinase (Chk) (3) Chloride Channel (6) Cholinesterase (ChE) (16) CMV (1) Complement System (5) COMT (5) COX (80) CRISPR/Cas9 (3) Cuproptosis (2) CXCR (1) Cyclophilin (2) Cytochrome P450 (33) Deubiquitinase (3) Dihydrofolate reductase (DHFR) (1) Dihydroorotate Dehydrogenase (2) Dipeptidyl Peptidase (15) Disulfidptosis (4) DNA Alkylator/Crosslinker (22) DNA Methyltransferase (7) DNA Stain (2) DNA/RNA Synthesis (101) Dopamine Receptor (43) Drug Metabolite (60) Drug-Linker Conjugates for ADC (6) DYRK (2) E1/E2/E3 Enzyme (7) EBI2/GPR183 (1) EGFR (29) Elastase (1) Endogenous Metabolite (811) Endothelin Receptor (3) Enterovirus (5) Epigenetic Reader Domain (4) ERK (9) Estrogen Receptor/ERR (39) Factor Xa (4) FAK (1) Fatty Acid Synthase (FASN) (3) Ferroptosis (51) FGFR (14) Filovirus (2) FKBP (4) Flavivirus (4) FLT3 (7) Fluorescent Dye (7) Free Fatty Acid Receptor (1) Fungal (69) FXR (4) G protein-coupled Bile Acid Receptor 1 (2) GABA Receptor (25) Gap Junction Protein (2) Gli (2) Glucocorticoid Receptor (25) Glucosidase (1) Glucosylceramide Synthase (GCS) (2) GLUT (2) Glutathione Reductase (1) Glutathione S-transferase (1) GlyT (2) GnRH Receptor (3) GPR35 (1) GPR55 (2) GSK-3 (6) HBV (9) HCV (23) HCV Protease (3) HDAC (20) Hedgehog (3) Hexokinase (1) HIF/HIF Prolyl-Hydroxylase (8) Histamine Receptor (37) Histone Acetyltransferase (10) Histone Demethylase (6) Histone Methyltransferase (9) HIV (68) HIV Integrase (11) HIV Protease (9) HMG-CoA Reductase (HMGCR) (15) HSP (8) HSV (15) IAP (1) IGF-1R (3) iGluR (19) IKK (2) Imidazoline Receptor (3) Indoleamine 2,3-Dioxygenase (IDO) (2) Influenza Virus (36) Insulin Receptor (1) Integrin (1) Interleukin Related (10) IRE1 (2) Isotope-Labeled Compounds (2032) JAK (12) JNK (2) Keap1-Nrf2 (15) Ketohexokinase (2) Kinesin (2) Leukotriene Receptor (9) Ligands for E3 Ligase (6) Ligands for Target Protein for PROTAC (3) Liposome (1) Lipoxygenase (3) LPL Receptor (7) mAChR (35) MDM-2/p53 (14) MEK (3) Melanocortin Receptor (1) Melatonin Receptor (9) mGluR (8) MicroRNA (1) Microtubule/Tubulin (27) Mineralocorticoid Receptor (10) Mitochondrial Metabolism (8) Mitophagy (41) MMP (9) Molecular Glues (10) Monoamine Oxidase (8) Monoamine Transporter (1) mTOR (6) Myosin (4) Na+/K+ ATPase (5) nAChR (13) NADPH Oxidase (1) Necroptosis (2) Neprilysin (7) Neurokinin Receptor (3) NF-κB (44) NO Synthase (21) NOD-like Receptor (NLR) (3) Notch (10) Nuclear Hormone Receptor 4A/NR4A (2) Nucleoside Antimetabolite/Analog (74) Opioid Receptor (3) Orexin Receptor (OX Receptor) (1) Orthopoxvirus (23) Oxidative Phosphorylation (1) P2X Receptor (1) P2Y Receptor (7) p38 MAPK (4) p97 (2) PAK (7) Parasite (93) PARP (6) PD-1/PD-L1 (1) PDGFR (19) PERK (1) PGC-1α (4) PGE synthase (1) Phosphatase (16) Phosphodiesterase (PDE) (24) Phospholipase (5) PI3K (4) PKA (2) PKC (16) Potassium Channel (31) PPAR (23) Progesterone Receptor (25) Prostaglandin Receptor (21) PROTAC Linkers (2) PROTACs (2) Protease Activated Receptor (PAR) (1) Proteasome (3) Proton Pump (22) RABV (1) Raf (7) RANKL/RANK (1) RAR/RXR (7) Ras (6) Reactive Oxygen Species (45) Renin (2) RET (7) Reverse Transcriptase (11) ROS Kinase (5) RSV (7) SARS-CoV (44) Ser/Thr Protease (3) Serotonin Transporter (26) SGLT (8) SHP2 (2) Sigma Receptor (1) Sirtuin (6) Small Interfering RNA (siRNA) (1) Sodium Channel (27) Src (6) STAT (13) Stearoyl-CoA Desaturase (SCD) (1) Syk (2) TAM Receptor (3) Tau Protein (1) TET Protein (3) TGF-beta/Smad (5) Thrombin (8) Thrombopoietin Receptor (3) Thymidylate Synthase (5) Thyroid Hormone Receptor (6) TNF Receptor (7) Toll-like Receptor (TLR) (4) TOPK (1) Topoisomerase (43) Trk Receptor (3) TRP Channel (15) Tyrosinase (6) Vasopressin Receptor (1) VD/VDR (14) VDAC (1) VEGFR (26) Virus Protease (17) Wee1 (1) Wnt (5) Xanthine Oxidase (3) YAP (2) β-catenin (7) γ-secretase (1)
By Research Areas:	Cancer (1084) Cardiovascular Disease (229) Endocrinology (194) Infection (487) Inflammation/Immunology (394) Metabolic Disease (380) Neurological Disease (421)
Click Chemistry:	Azide (3) Alkynes (18)
Oligonucleotides:	Nucleosides and their Analogs (2) Pre-designed siRNA Sets (1) siRNAs (1)

3539

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

153

Natural
Products

Recombinant Proteins

2930

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Oligonucleotides

Targets Recommended: P-glycoprotein

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-Y1630S

NSC 10281-d4 Para-fluoronitrobenzene-d<sub>4sub>; p-Fluoronitrobenzene-d<sub>4sub>; p-Nitrofluorobenzene-d<sub>4sub>	Isotope-Labeled Compounds	Others
NSC 10281-d₄ is the deuterium labeled NSC 10281[1].

HY-17393S

Carboplatin-d4 NSC 241240-d<sub>4sub>	Isotope-Labeled Compounds DNA Alkylator/Crosslinker Autophagy DNA/RNA Synthesis	Cancer
Carboplatin-d₄ is the deuterium labeled Carboplatin. Carboplatin (NSC 241240) is a DNA synthesis inhibitor which binds to DNA, inhibits replication and transcription and induces cell death. Carboplatin (NSC 241240) is a derivative of CDDP and a potent anti-cancer agent.

HY-Y1042S

4-Cyanophenol-d4 4-Hydroxybenzonitrile-d<sub>4sub>; 4-Hydroxycyanobenzene-d<sub>4sub>; NSC 400524-d<sub>4sub>	Isotope-Labeled Compounds	Others
4-Cyanophenol-d₄ is the deuterium labeled 4-Cyanophenol[1].

HY-Y0226S1

NSC 1940-d8	Isotope-Labeled Compounds	Others
NSC 1940-d₈ is the deuterium labeled NSC 1940[1].

HY-Y0226S2

NSC 1940-d4	Isotope-Labeled Compounds	Others
NSC 1940-d₄ is the deuterium labeled NSC 1940[1].

HY-Y1675S

NSC 65593-d4 m-Acetylanisole-d<sub>4sub>; m-Methoxyacetophenone-d<sub>4sub>	Isotope-Labeled Compounds	Others
NSC 65593-d₄ is the deuterium labeled NSC 65593[1].

HY-B0246S4

Carbamazepine-d4 CBZ-d<sub>4sub>; NSC 169864-d<sub>4sub>	Isotope-Labeled Compounds	Others
Carbamazepine-d4 (CBZ-d4; NSC 169864-d4) is the deuterium labeled Carbamazepine-d4 (HY-B0246S4) .

HY-N5034S

Phosphorylethanolamine-d4 Monoaminoethyl phosphate-d<sub>4sub>; NSC 254167-d<sub>4sub>; O-Phosphoethanolamine-d<sub>4sub>	Isotope-Labeled Compounds	Metabolic Disease
Phosphorylethanolamine-d₄ (Monoaminoethyl phosphate-d₄; NSC 254167-d₄) is a deuterium labeled Phosphorylethanolamine (HY-N5034). Phosphorylethanolamine is an endogenous metabolite.

HY-RS13999

SUB1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SUB1 Human Pre-designed siRNA Set A contains three designed siRNAs for SUB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SUB1 Human Pre-designed siRNA Set A SUB1 Human Pre-designed siRNA Set A

HY-146227

DNA topoisomerase II inhibitor 1	Topoisomerase Apoptosis	Cancer
DNA topoisomerase II inhibitor 1 (compound 8ed) is a potent DNA topoisomerase II inhibitor. DNA topoisomerase II inhibitor 1 shows anti-proliferative activity. DNA topoisomerase II inhibitor 1 induces apoptosis and cell cycle arrest at sub G1 phase .

HY-79576S

NSC 88911-d3 Oestrone methyl ether-d<sub>3sub>; 3-O-Methylestrone-d<sub>3sub>	Isotope-Labeled Compounds	Cancer
NSC 88911-d₃ is the deuterium labeled NSC 88911[1].

HY-Y0093S

NSC 5416-d14 α,ω-Nonanediol-d<sub>14sub>; 1,9-Dihydroxynonane-d<sub>14sub>; Nonamethylene Glycol-d<sub>14sub>	Isotope-Labeled Compounds	Others
NSC 5416-d₁₄ is the deuterium labeled NSC 5416[1].

HY-Y0124S

NSC 16590-d6 α,α-Dimethylglycine-d<sub>6sub>; α-Aminoisobutanoic acid-d<sub>6sub>	Isotope-Labeled Compounds Endogenous Metabolite	Others
NSC 16590-d₆ is the deuterium labeled NSC 16590. NSC 16590 inhibits the production of endogenous ethylene in the cotyledonary segments of cocklebur.

HY-B0217S

Nitazoxanide-d4 NTZ-d<sub>4sub>; NSC-697855-d<sub>4sub>	Influenza Virus	Others
Nitazoxanide-d₄ is the deuterium labeled Nitazoxanide, which is an antiprotozoal agent.

HY-N1150S1

Thymidine-d4 DThyd-d<sub>4sub>; NSC 21548-d<sub>4sub>	DNA/RNA Synthesis Endogenous Metabolite	Others
Thymidine-d₄ is the deuterium labeled Thymidine. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication[1][2][3].

HY-100048S

Acetylisoniazid-d4 Acetylisoniazide-d<sub>4sub>; N-Monoacetylisoniazid-d<sub>4sub>; NSC 36084-d<sub>4sub>	Isotope-Labeled Compounds	Others
Acetylisoniazid-d₄ is the deuterium labeled Acetylisoniazid[1].

HY-Y0085S

NSC 190686-d3 3,4-Difluorobenzoic acid-d<sub>3sub>	Isotope-Labeled Compounds	Others
NSC 190686-d₃ is the deuterium labeled NSC 190686[1].

HY-153719

NSC111552	SARS-CoV	Infection
NSC111552 is a potent SARS-CoV-2 NSP14 MTase inhibitor. NSC111552 inhibits the FL-NAH binding to the SARS-CoV-2 NSP14 MTase with an IC₅₀ of 5.1 μM .

HY-10844S1

Pretomanid-d5 PA-824-d<sub>5sub>; (S)-PA 824-d<sub>5sub>	Antibiotic Bacterial Isotope-Labeled Compounds	Infection Cancer
Pretomanid-d₅ is deuterated labeled Pretomanid (HY-10844). Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 μg/mL.

HY-B0504S2

Creatinine-d5 NSC13123-d<sub>5sub>	Endogenous Metabolite	Metabolic Disease
Creatinine-d₅ is the deuterium labeled Creatinine. Creatinine (NSC13123) is a break-down product of creatine phosphate in muscle, and is usually produced at a fairly constant rate by the body.

HY-123533S

Resorufin-d6 NSC 12097-d<sub>6sub>	Reactive Oxygen Species	Others
Resorufin-d₆ is the deuterium labeled Resorufin. Resorufin (NSC 12097) is a highly fluorescent pink dye for the detection of ROS/RNS and a second analyte[1].

HY-W022039S

(Benzyloxy)benzene-d2 NSC 77971-d<sub>2sub>	Isotope-Labeled Compounds	Others
(Benzyloxy)benzene-d2 (NSC 77971-d2) is the deuterium labeled Benzyloxybenzene (HY-W022039) .

HY-B1944S

Dipropyl phthalate-d4 NSC 15314-d<sub>4sub>; Di-n-Propyl phthalate-d<sub>4sub>	Isotope-Labeled Compounds	Others
Dipropyl phthalate-d₄ is the deuterium labeled Dipropyl phthalate[1].

HY-B1556S

Benzyl salicylate-d4 NSC 6647-d<sub>4sub>	Isotope-Labeled Compounds	Others
Benzyl salicylate-d₄ is the deuterium labeled Benzyl salicylate[1].

HY-41680S

4-Aminobenzonitrile-d4 4-Aminobenzonitrile-d<sub>4sub>; 4-Cyanoaniline-d<sub>4sub>; 4-Cyanobenzenamine-d<sub>4sub>	Isotope-Labeled Compounds	Others
4-Aminobenzonitrile-d₄ is the deuterium labeled 4-Aminobenzonitrile[1].

HY-66005S

Acetaminophen-d4 Paracetamol-d<sub>4sub>; 4-Acetamidophenol-d<sub>4sub>; 4'-Hydroxyacetanilide-d<sub>4sub>	COX Histone Acetyltransferase Endogenous Metabolite	Inflammation/Immunology
Acetaminophen-d₄ is the deuterium labeled Acetaminophen. Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM; is a widely used antipyretic and analgesic agent[1][2][3]. Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor[4].

HY-N1150S10

Thymidine-d14 DThyd-d<sub>14sub>; NSC 21548-d<sub>14sub>	Isotope-Labeled Compounds DNA/RNA Synthesis Endogenous Metabolite Orthopoxvirus	Cancer
Thymidine-d₁₄ (DThyd-d₁₄; NSC 21548-d₁₄) is deuterium labeled Thymidine (HY-N1150). Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication.

HY-W016389S

9H-Fluoren-2-ol-d9 NSC 31248-d<sub>9sub>	Isotope-Labeled Compounds	Others
9H-Fluoren-2-ol-d₉ (NSC 31248-d₉) is a deuterium labeled compound.

HY-W779017

Thymidine-13C5 DThyd-¹³C<sub>5sub>; NSC 21548-¹³C<sub>5sub>	Orthopoxvirus Endogenous Metabolite DNA/RNA Synthesis Isotope-Labeled Compounds	Others
Thymidine- ¹³C₅ (DThyd- ¹³C₅; NSC 21548- ¹³C₅) is ¹³C-labeled Thymidine (HY-N1150) .

HY-B2150S

4-Hydroxyantipyrine-d3 4-Hydroxyphenazone-d<sub>3sub>; NSC 174055-d<sub>3sub>	Drug Metabolite Isotope-Labeled Compounds	Others
4-Hydroxyantipyrine-d₃ is the deuterium labeled 4-Hydroxyantipyrine. 4-Hydroxyantipyrine is the major metabolite of Antipyrine, can be as a biodistribution promoter. 4-Hydroxyantipyrine can increase distribution of concentration ratio of Antipyrine in the brain[1][2][3].

HY-17413S2

Zidovudine-d4 Azidothymidine-d<sub>4sub>; AZT-d<sub>4sub>; ZDV-d<sub>4sub>	CRISPR/Cas9 HIV Isotope-Labeled Compounds	Infection Cancer
Zidovudine-d₄ is deuterated labeled Zidovudine (HY-17413). Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection. Zidovudine increases CRISPR/Cas9-mediated editing frequency.

HY-B0094S3

Artemisinin-13C,d4 Qinghaosu-¹³C,d<sub>4sub>; NSC 369397-13C,d<sub>4sub>	Ferroptosis Akt Parasite HCV Isotope-Labeled Compounds	Infection Neurological Disease Cancer
Artemisinin- ¹³C,d₄ is ¹³C and deuterated labeled Artemisinin (HY-B0094). Artemisinin (Qinghaosu), a sesquiterpene lactone, is an anti-malarial agent isolated from the aerial parts of Artemisia annua L. plants . Artemisinin inhibits AKT signaling pathway by decreasing pAKT in a dose-dependent manner. Artemisinin reduces cancer cell proliferation, migration, invasion, tumorigenesis and metastasis and has neuroprotective effects .

HY-Y0484S

1-Indanamine-d9 hydrochloride 1-Aminoindan-d<sub>9sub> hydrochloride; 1-Aminoindane-d<sub>9sub> hydrochloride; NSC 186227-d<sub>9sub> hydrochloride; 1-Aminoindane-d<sub>9sub> hydrochloride	Isotope-Labeled Compounds	Others
1-Indanamine-d₉ (1-Aminoindan-d₉; 1-Aminoindane-d₉; NSC 186227-d₉; 1-Aminoindane-d₉) hydrochloride is deuterium-labeled 1-Indanamine hydrochloride (HY-Y0484) .

HY-Y0219S1

1,2,4-Triazole-d3 s-Triazole-d<sub>3sub>; Pyrrodiazole-d<sub>3sub>	Isotope-Labeled Compounds	Others
NSC 83128-d₃ is the deuterium labeled NSC 83128[1].

HY-B1008S

4-Aminobenzoic acid-d4 PABA-d<sub>4sub>; Vitamin Bx-d<sub>4sub>; Vitamin H1-d<sub>4sub>; p-Aminobenzoic acid-d<sub>4sub>	Isotope-Labeled Compounds Endogenous Metabolite	Others
4-Aminobenzoic acid-d₄ is the deuterium labeled 4-Aminobenzoic acid. 4-Aminobenzoic acid is an intermediate in the synthesis of folate by bacteria, plants, and fungi.

HY-N0006S1

Demethoxycurcumin-d4 Curcumin II-d<sub>4sub>; Desmethoxycurcumin-d<sub>4sub>; Monodemethoxycurcumin-d<sub>4sub>	Apoptosis Autophagy Bacterial	Cancer
Demethoxycurcumin-d₄ is the deuterium labeled Demethoxycurcumin. Demethoxycurcumin (Curcumin II) is a major active curcuminoid; possess anti-inflammatory properties[1].

HY-N0055S

Chlorogenic acid-13C3 3-O-Caffeoylquinic acid-<sub>13sub>C³; Heriguard-<sub>13sub>C³; NSC-407296-<sub>13sub>C³	Isotope-Labeled Compounds	Cancer
Chlorogenic acid- ¹³C₃ (Heriguard- ¹³C₃; NSC-407296- ¹³C₃) is ¹³C- and ¹⁵N-labeled Chlorogenic acid (HY-N0055). Chlorogenic acid is a major phenolic compound in Lonicera japonica Thunb.. It plays several important and therapeutic roles such as antioxidant activity, antibacterial, hepatoprotective, cardioprotective, anti-inflammatory, antipyretic, neuroprotective, anti-obesity, antiviral, anti-microbial, anti-hypertension .

HY-B0678S1

Metaxalone-d6 AHR438-d<sub>6sub>; NSC170959-d<sub>6sub>	Isotope-Labeled Compounds NF-κB PGC-1α	Neurological Disease Inflammation/Immunology
Metaxalone-d₆ is deuterium labeled Metaxalone. Metaxalone (AHR438; NSC170959) is an FDA-approved muscle relaxant. Metaxalone acts mainly on the central nervous system and achieves muscle relaxation by inhibiting polysynaptic reflex arcs. In addition, Metaxalone is an inhibitor of MAO-A, which has anti-inflammatory and antioxidant effects. Metaxalone inhibits IL-1β-induced inflammatory phenotype, modulates NF-κB and other related signaling pathways, and decreases MAO-A expression and activity in IL-1β-treated microglia .

HY-Y0251S

3-Nitrophthalic acid-d3 m-Nitrophthalic acid-d<sub>3sub>; o-Nitrophthalic acid-d<sub>3sub>	Isotope-Labeled Compounds	Others
NSC 3120-d₃ is the deuterium labeled NSC 3120[1].

HY-B0329S

Isoniazid-d4 INH-d<sub>4sub>; Isonicotinic acid hydrazide-d<sub>4sub>; Isonicotinic hydrazide-d<sub>4sub>	Bacterial Autophagy Mitophagy Antibiotic	Infection
Isoniazid-d₄ is the deuterium labeled Isoniazid. Isoniazid (INH) is a proagent and must be activated by a bacterial catalase-peroxidase enzyme KatG. Isoniazid is bactericidal to rapidly dividing mycobacteria and has anti-tuberculostatic activity[1][2][3][4].

HY-118861S

Enclomiphene-d4 hydrochloride (E)-Clomiphene-d<sub>4sub> hydrochloride; trans-Clomiphene-d<sub>4sub> hydrochloride; Enclomifene-d<sub>4sub> hydrochloride	Isotope-Labeled Compounds Estrogen Receptor/ERR	Inflammation/Immunology
Enclomiphene-d₄ (hydrochloride) is a deuterium labeled Enclomiphene. Enclomiphene-d₄ (hydrochloride) is a potent and orally active oestrogen receptor antagonist, with antioestrogenic property[1].

HY-109015S

Tucidinostat-d4 Chidamide-d<sub>4sub>; HBI-8000-d<sub>4sub>; CS 055-d<sub>4sub>	Isotope-Labeled Compounds HDAC	Cancer
Tucidinostat-d₄ is the deuterium labeled Tucidinostat. Tucidinostat is a potent and orally bioavailable HDAC enzymes class I (HDAC1/2/3) and class IIb (HDAC10) inhibitor, with IC50s of 95, 160, 67 and 78 nM, respectively[1].

HY-19696AS

Tauroursodeoxycholate-d4 sodium Tauroursodeoxycholic acid-d<sub>4sub> sodium; TUDCA-d<sub>4sub> sodium; UR 906-d<sub>4sub> sodium	Isotope-Labeled Compounds ERK Caspase Apoptosis Endogenous Metabolite	Cancer
Tauroursodeoxycholate-d₄ (sodium) is the deuterium labeled Tauroursodeoxycholate sodium. Tauroursodeoxycholate (Tauroursodeoxycholic acid; TUDCA) sodium is an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12. Tauroursodeoxycholate also inhibits ERK.

HY-19696S1

Tauroursodeoxycholate-d4 Tauroursodeoxycholic acid-d<sub>4sub>; TUDCA-d<sub>4sub>; UR 906-d<sub>4sub>	Isotope-Labeled Compounds ERK Caspase Endogenous Metabolite Apoptosis	Cancer
Tauroursodeoxycholate-d₄ is deuterium labeled Tauroursodeoxycholate. Tauroursodeoxycholate (Tauroursodeoxycholic acid) is an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12. Tauroursodeoxycholate also inhibits ERK.

HY-B0389S24

D-Glucose-d4 Glucose-d<sub>4sub>; D-(+)-Glucose-d<sub>4sub>; Dextrose-d<sub>4sub>	Endogenous Metabolite	Metabolic Disease Cancer
D-Glucose-d₄ is the deuterium labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molec

HY-B0696AS

Tiagabine-d4 hydrochloride NO050328-dd<sub>4sub> hydrochloride; NO328-d<sub>4sub> hydrochloride; TGB-d<sub>4sub> hydrochloride	GABA Receptor Isotope-Labeled Compounds	Neurological Disease
Tiagabine-d₄ hydrochloride is deuterated labeled Tiagabine hydrochloride (HY-B0696A). Tiagabine hydrochloride is a potent and selective GABA reuptake inhibitor, used as an anticonvulsant agent, with IC₅₀s of 67, 446 and 182 nM for [ ³H]GABA uptake in Synaptosomes, Neurons and Glia, respectively .

HY-13273S

Ostarine-d4 MK-2866-d<sub>4sub>; GTX-024-d<sub>4sub>; Enobosarm-d<sub>4sub>	Isotope-Labeled Compounds Androgen Receptor	Cancer
Ostarine-d4 is a deuterated labeled Ostarine .

HY-Y0219S

1,2,4-Triazole-13C2,15N3 s-Triazole¹³C<sub>2sub>,¹⁵N<sub>3sub>; Pyrrodiazole¹³C<sub>2sub>,¹⁵N<sub>3sub>	Isotope-Labeled Compounds	Others
NSC 83128- ¹³C₂, ¹⁵N₃ is the ¹³C and ¹⁵N labeled NSC 83128[1].

HY-34498S

4-Chloro-2-methylphenol-d4 4-Chloro-o-cresol-d<sub>4sub>; 4-Chlorocresol-d<sub>4sub>; 5-Chloro-2-hydroxytoluene-d<sub>4sub>	Isotope-Labeled Compounds	Others
4-Chloro-2-methylphenol-d₄ is the deuterium labeled 4-Chloro-2-methylphenol[1].

HY-107542S

Oleoylethanolamide-d4 N-Oleoylethanolamide-d<sub>4sub>; Oleamide MEA-d<sub>4sub>; Oleic acid monoethanolamide-d<sub>4sub>	Isotope-Labeled Compounds Endogenous Metabolite PPAR	Cardiovascular Disease Metabolic Disease
Oleoylethanolamide-d₄ is the deuterium labeled Oleoylethanolamide. Oleoylethanolamide is a high affinity endogenous PPAR-α agonist, which plays an important role in the treatment of obesity and arteriosclerosis.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-125833

Alpha-Naphthoflavone 5+ Cited Publications	Flavonoids Flavones Source classification Indigofera heterantha Wall. ex Brand. Plants Compositae Disease Research Fields Cancer	Cytochrome P450 Aryl Hydrocarbon Receptor Apoptosis
Alpha-Naphthoflavone is an orally active flavonoid that is a potent, competitive inhibitor of aromatase< b>aromatase. < b > IC < sub > 50 < / sub > < / b > and < b > K < sub > I < / sub > < / b > value were 0.5 and 0.2 microns. Alpha-Naphthoflavone can inhibit cell proliferation and induce apoptosis ^[4].

HY-W751835

Baloxavir-d4 25+ Cited Publications Baloxavir acid-d<sub>4sub>; S-033447-d<sub>4sub>	Classification of Application Fields Disease Research Fields Cancer	Isotope-Labeled Compounds
Baloxavir-d₄ (Baloxavir acid-d₄; S-033447-d₄) is the deuterium-labeled Baloxavir (HY-109025A). Baloxavir-d₄ (Baloxavir-d₄ acid), derived from the proagent Baloxavir-d₄ marboxil, is a first-in-class, potent and selective cap-dependent endonuclease (CEN) inhibitor within the polymerase PA subunit of influenza A and B viruses. Baloxavir-d₄ inhibits viral RNA transcription and replication and has potently antiviral activity .

HY-N0837

Veratramine 1 Publications Verification NSC17821; NSC23880	Alkaloids Piperidine Alkaloids Structural Classification other families Classification of Application Fields Source classification Plants Disease Research Fields Cancer	Others
Veratramine(NSC17821; NSC23880) is useful as a signal transduction inhibitor for treating tumors.

HY-B1476

NSC 42196	Structural Classification Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Saccharides	Endogenous Metabolite
NSC 42196 is an endogenous metabolite.

HY-15733

Lucidin 1 Publications Verification NSC 30546	Quinones Classification of Application Fields Anthraquinones Source classification Rubiaceae Phenols Polyphenols Plants Disease Research Fields Cancer Rubia cordifolia L.	Others
Lucidin (NSC 30546) is a natural component of Rubia cordifolia.

HY-B0504S

Creatinine-d3 3 Publications Verification NSC13123-d<sub>3sub>	Classification of Application Fields Metabolic Disease Disease Research Fields	Endogenous Metabolite
Creatinine-d₃ is a deuterium labeled Creatinine. Creatinine is a break-down product of creatine phosphate in muscle[1].

HY-B1476R

NSC 42196 (Standard)	Structural Classification Source classification Endogenous metabolite Saccharides	Endogenous Metabolite
NSC 42196 (Standard) is the analytical standard of NSC 42196. This product is intended for research and analytical applications. NSC 42196 is an endogenous metabolite.

HY-114557R

NSC 90469 (Standard)	Structural Classification Monophenols Ketones, Aldehydes, Acids Source classification Phenols Endogenous metabolite	Endogenous Metabolite
NSC 90469 (Standard) is the analytical standard of NSC 90469. This product is intended for research and analytical applications. NSC 90469 is an endogenous metabolite.

HY-Y0124R

NSC 16590 (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Pterocarpus soyauxii Taub. Source classification Plants Compositae Endogenous metabolite	Endogenous Metabolite
NSC 16590 (Standard) is the analytical standard of NSC 16590. This product is intended for research and analytical applications. NSC 16590 inhibits the production of endogenous ethylene in the cotyledonary segments of cocklebur.

HY-N11799

Neochilenin 3-O-Methylquercetin 4′-O-glucoside	Structural Classification Flavonoids Source classification Plants Compositae Other Flavonoids	Others
Neochilenin (3-O-Methylquercetin 4 '-O-glucoside) is a glycoside of 3-O-methylquercetin, which can be isolated from the sub-family Cereoideae (Cactaceae). .

HY-15753

Ellipticine 3 Publications Verification NSC 71795	Apocynaceae Alkaloids Structural Classification Classification of Application Fields Source classification Plants Amsonia elliptica (Thunberg ex Murray) Roemer & Schultes Disease Research Fields Indole Alkaloids Cancer	Topoisomerase
Ellipticine (NSC 71795) is a potent antineoplastic agent; inhibits DNA topoisomerase II activities.

HY-15753A

Ellipticine hydrochloride 3 Publications Verification NSC 71795 hydrochloride	Apocynaceae Alkaloids Structural Classification Classification of Application Fields Source classification Plants Amsonia elliptica (Thunberg ex Murray) Roemer & Schultes Disease Research Fields Indole Alkaloids Cancer	Topoisomerase
Ellipticine (NSC 71795) hydrochloride is a potent antineoplastic agent; inhibits DNA topoisomerase II activities.

HY-N3738

Demethoxycentaureidin NSC 689466	Structural Classification Flavonoids Flavones Source classification Peucephyllum schottii A.Gray Plants Compositae	Others
Demethoxycentaureidin (NSC 689466) is a natural product that can be isolated from Peucephyllum schottii .

HY-114557

NSC 90469 3,5-Diiodo-L-thyronine	Structural Classification Monophenols Classification of Application Fields Ketones, Aldehydes, Acids Source classification Phenols Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
NSC 90469 is an endogenous metabolite.

HY-N4284

Angelicolide NSC 382182	Structural Classification Natural Products Source classification Umbelliferae Plants Echinacea angustifolia DC.	Others
Angelicolide (NSC 382182) is a Phenols product that can be isolated from the herbs of Schisandra propinqua .

HY-79494

Glyoxalic acid 1 Publications Verification NSC 27785; Formylformic acid; Oxalaldehydic acid	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Disease markers Other Diseases Endocrine diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Glyoxalic acid (NSC 27785) is an organic compound that is both an aldehyde and a carboxylic acid.

HY-N1903

NSC 648342 4-Hydroxysapriparaquinone	Quinones Structural Classification Labiatae Source classification Salvia prionitis Hance Plants Naphthalene Quinones	Others
NSC 648342 (4-Hydroxysapriparaquinone) is a product that can be isolated from .

HY-N4277

Methyl protogracillin NSC-698793	Other Terpenoids other families Classification of Application Fields Terpenoids Source classification Plants Disease Research Fields Cancer	Others
Methyl protogracillin (NSC-698793), isolated from the roots of Dioscorea opposite Thunb, exhibits strong anti-cancer activity .

HY-N12219

Pyridindolol NSC 266530	Structural Classification Alkaloids Microorganisms Source classification Indole Alkaloids	Endogenous Metabolite
Pyridindolol (NSC 266530) is a β-galactosidase inhibitor. Pyridindolol can be produced by actinomycetes .

HY-N1107

Uzarigenin NSC 119993; NSC 277290; Odorigeni	Apocynaceae Structural Classification Cardiacglycosides Source classification Plants Steroids	Others
Uzarigenin (NSC 119993; NSC 277290; Odorigeni) is a carnolide can be isolated from Pergularia tomentosa and exhibits antiproliferative activity. Uzarigenin resists the proliferation of PC3 cells, HeLa cells, Calu-1 cells, MCF-7 cells and U251MG cells, with IC₅₀ values of 0.3 μM, 3.0 μM, 8.0 μM, 6.0 μM and 6.0 μM respectively .

HY-W011474

Geranylgeraniol	Structural Classification Natural Products Microorganisms	NF-κB
Geranylgeraniol is an orally acitve vitamin K₂ sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model ^[4].

HY-19543

Brusatol 25+ Cited Publications NSC 172924	Structural Classification Simaroubaceae Classification of Application Fields Terpenoids Source classification Diterpenoids Plants Disease Research Fields Brucea javanica (L.) Merr. Cancer	Keap1-Nrf2 Apoptosis
Brusatol (NSC 172924) is a unique inhibitor of the Nrf2 pathway that sensitizes a broad spectrum of cancer cells to Cisplatin and other chemotherapeutic agents. Brusatol enhances the efficacy of chemotherapy by inhibiting the Nrf2-mediated defense mechanism. Brusatol can be developed into an adjuvant chemotherapeutic agent . Brusatol increases cellular apoptosis .

HY-N10687

Saprorthoquinone NSC 648341	Quinones Structural Classification Labiatae Source classification Plants Naphthalene Quinones Vachellia nilotica (L.) P. J. H. Hurter & Mabb.	Others
Saprorthoquinone (NSC 648341) is a diterpenoid that can be found in salvia atropatana. Saprorthoquinone shows cytotoxicity for PC3 cells .

HY-B0504

Creatinine 5 Publications Verification NSC13123	Infection Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Disease markers Endocrine diseases Metabolic Disease Nervous System Disorder Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Creatinine (NSC13123) is a breakdown product of creatine phosphate in muscles.

HY-N3766

Diosbulbin G NSC 310635	Structural Classification Terpenoids Source classification Diterpenoids Plants Dioscorea bulbifera Linn. Dioscoreaceae	Others
Diosbulbin G (NSC 310635) is a Diterpenoids product that can be isolated from the barks of Pinus massoniana Lamb. .

HY-114502

Chrysanthemic acid NSC 11779	Structural Classification Tanacetum cinerariifolium (Treviranus) Schultz Bipontinus Ketones, Aldehydes, Acids Source classification Plants Compositae	Others
Chrysanthemic acid (NSC 11779) is an organic compound that is associated with a variety of natural and synthetic insecticides for the prevention of insect-borne diseases, among others .

HY-Y0057

NSC 13138 Cinchoninic acid (6CI,7CI,8CI); 4-Carboxyquinoline	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
NSC 13138 is an endogenous metabolite.

HY-N4315

Pomiferin 1 Publications Verification NSC 5113	Classification of Application Fields Source classification Phenols Polyphenols Maclura pomifera (Raf.) Schneid. Plants Moraceae Disease Research Fields Cancer	HDAC mTOR
Pomiferin (NSC 5113) acts as an potential inhibitor of HDAC, with an IC₅₀ of 1.05 μM, and also potently inhibits mTOR (IC₅₀, 6.2 µM).

HY-Y1644

NSC 8751 (E)-2-Butenoic acid; (E)-Crotonic acid; trans-2-Butenoic acid; trans-Crotonic acid	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
NSC 8751 is an endogenous metabolite.

HY-N1293

Serpentinine NSC72123	Apocynaceae Rauvolfia verticillata (Lour.) Baill. Structural Classification Alkaloids Rauvolfia serpentina Source classification Plants Indole Alkaloids	Others
Serpentinine (NSC72123) is an alkaloid isolated from Rauwolfia serpentina Benth .

HY-B1777

Spermine 3 Publications Verification NSC 268508; Neuridine	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite Influenza Virus
Spermine (NSC 268508) functions directly as a free radical scabenger to protect DNA from free radical attack. Spermine has antiviral effects.

HY-114917

Aldophosphamide NSC 254	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields Cancer	Drug Metabolite Endogenous Metabolite
Aldophosphamide (NSC 254) is a cyclophosphamide metabolite. Aldophosphamide is cleaved intracellularly to phosphoramide mustard, an active metabolite with direct cytotoxicity, and acrolein. Aldophosphamide has potential for cancer research .

HY-13764

Tetrandrine 5+ Cited Publications NSC-77037; d-Tetrandrine	Stephania tetrandra S. Moore Alkaloids Structural Classification Classification of Application Fields Source classification Plants Menispermaceae Inflammation/Immunology Disease Research Fields Alkaloid Dimers	Calcium Channel Potassium Channel Parasite
Tetrandrine (NSC-77037; d-Tetrandrine) is a bis-benzyl-isoquinoline alkaloid, which inhibits voltage-gated Ca ²⁺ current (ICa) and Ca ²⁺-activated K ⁺ current.

HY-Y0124

NSC 16590 α,α-Dimethylglycine; α-Aminoisobutanoic acid	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Pterocarpus soyauxii Taub. Source classification Other Diseases Plants Compositae Endogenous metabolite Disease Research Fields	Endogenous Metabolite
NSC 16590 inhibits the production of endogenous ethylene in the cotyledonary segments of cocklebur.

HY-112058

Distamycin A NSC-82150	Structural Classification Natural Products Microorganisms Source classification	Antibiotic Apoptosis
Distamycin A (NSC-82150), an oligopeptide antibiotic, is a minor groove binder which binds to B-form DNA, preferentially at A/T rich sites.Distamycin A can change Enediyne-induced DNA cleavage sites and enhances apoptosis .

HY-N3655

Cyclo(D-Phe-L-Pro) NSC 255998	Structural Classification Alkaloids Microorganisms Other Alkaloids Source classification	Others
Cyclo(D-Phe-L-Pro) (NSC 255998) is a flavonoid product that can be isolated from Rhododendron mucronulatum .

HY-N1297

Sesartemin NSC380470	Structural Classification Araceae Source classification Lignans Rhaphidophora decursiva (Roxb.) Schott Phenylpropanoids Plants	Others
Sesartemin (NSC380470) is a Xanthones product that can be isolated from the stem barks of Calophyllum inophyllum. .

HY-N0004

Oridonin 15+ Cited Publications NSC-250682; Isodonol	Infection Structural Classification Classification of Application Fields Terpenoids Labiatae Diterpenoids Emilia sonchifolia (L.) DC. Plants Inflammation/Immunology Disease Research Fields	Akt Bacterial
Oridonin (NSC-250682), a diterpenoid isolated from Rabdosia rubescens, acts as an inhibitor of AKT, with IC₅₀s of 8.4 and 8.9 μM for AKT1 and AKT2; Oridonin possesses anti-tumor, anti-bacterial and anti-inflammatory effects.

HY-101413

Iberin 1 Publications Verification NSC 321801	Structural Classification Natural Products other families Classification of Application Fields Source classification Plants Endogenous metabolite Disease Research Fields Cancer	Apoptosis Endogenous Metabolite Bacterial
Iberin (NSC 321801), a sulfoxide analogue of sulforaphane, is a naturally occurring member of isothiocyanate family. Iberin inhibits cell survival with an IC₅₀ of 2.3 μM in HL60 cell. Iberin induces apoptosis.

HY-114772

Methyl reserpate NSC 81464; Me reserpate	Apocynaceae Structural Classification Alkaloids Source classification Rauvolfia vomitoria Afzel. Plants	Others
Methyl reserpate (NSC 81464) is a Yohimbine (HY-12715) type alkaloid, that can be isolated from Rauwolfia vomitoria roots and leaves .

HY-N3272

Methyl levulinate Methyl β-acetylpropionate; NSC 24874	Apocynaceae Structural Classification Natural Products Source classification Rauvolfia vomitoria Afzel. Plants	Others
Methyl levulinate (NSC 24874) is a Alkaloids product that can be isolated from the stems and leaves of Ervatamia hainanensis. .

HY-105697

Protoveratrine A NSC 7526; Protalba; Protoveratrin	Structural Classification Alkaloids Piperidine Alkaloids Veratrum nigrum Linn. Liliaceae Source classification Plants	Others
Protoveratrine A (NSC 7526; Protalba; Protoveratrin) is an alkaloid with strong cardiostimulant and vasoconstrictive effects, which can be used in the study of hypertension and other cardiovascular diseases .

HY-105529

Indicine N-oxide (+)-Indicine N-oxide; NSC 132319	Alkaloids Structural Classification Pyrrole Alkaloids Classification of Application Fields Tournefortia argentea Linnaeus f. Source classification Plants Disease Research Fields Boraginaceae Cancer	Others
Indicine N-oxide (NSC 132319), a pyrrolizidine alkaloid, is an antitumor agent for pediatric cancer and solid tumors research .

HY-13555

β-Lapachone 5+ Cited Publications ARQ-501; NSC-26326	Quinones Structural Classification other families Classification of Application Fields Source classification Plants Naphthalene Quinones Disease Research Fields Cancer	Indoleamine 2,3-Dioxygenase (IDO) Topoisomerase Autophagy Apoptosis
β-Lapachone (ARQ-501;NSC-26326) is a naturally occurring O-naphthoquinone, acts as a topoisomerase I inhibitor, and induces apoptosis by inhibiting cell cycle progression.

HY-P2274

Argifin	Infection Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields	Parasite
Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms, with IC₅₀s of 0.025 μM, 6.4 μM , 1.1 μM and 4.5 μM for SmChiA (Serratia marcescens chitinaese A), SmChiB, Aspergillus fumigatus chitinase B1 and human chitotriosidase, respectively .

HY-118724

Laetrile NSC103055; Mandelonitrile beta-glucuronide	Structural Classification Natural Products Source classification Rosaceae Plants Rosa multifoloraThunb	Others
Laetrile (NSC103055) is a natural product .

HY-118166

Gentisein NSC 329491; 1,3,7-Trihydroxyxanthone	other families Xanthones Classification of Application Fields Neurological Disease Source classification Phenols Polyphenols Plants Disease Research Fields	5-HT Receptor
Gentisein (NSC 329491), the major metabolite of Mangiferin, shows the most potent serotonin uptake inhibition with an IC₅₀ value of 4.7 µM .

HY-118384

Sangivamycin 2 Publications Verification NSC 65346; BA-90912	Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields Cancer	PKC Nucleoside Antimetabolite/Analog
Sangivamycin (NSC 65346), a nucleoside analog, is a potent inhibitor of protein kinase C (PKC) with an K_i of 10 μM. Sangivamycin has potent antiproliferative activity against a variety of human cancers .

HY-125461

Altersolanol A Stemphylin; NSC 173943	Quinones Structural Classification Taxaceae Source classification Benzene Quinones Plants Taxus wallichiana Zucc.	Bacterial
Altersolanol A (Stemphylin; NSC 173943) exhibits antimicrobial activities against Bacillus subtilis and Pseudomonas aeruginosa, with MIC of 25-100 μg/mL. Altersolanol A exhibits no phytotoxicity to Taxus (at dose of 4 μg/μL) .

HY-N1766

3',4',5',3,5,6,7-Heptamethoxyflavone NSC 684433	Structural Classification Flavonoids Flavones Source classification Rutaceae Plants Citrus sinensis (L.) Osbeck	Others
3',4',5',3,5,6,7-Heptamethoxyflavone (NSC 684433) is a product that can be isolated from .

Cat. No.	Product Name	Chemical Structure

HY-Y1630S

NSC 10281-d4
NSC 10281-d₄ is the deuterium labeled NSC 10281[1].

HY-17393S

Carboplatin-d4
Carboplatin-d₄ is the deuterium labeled Carboplatin. Carboplatin (NSC 241240) is a DNA synthesis inhibitor which binds to DNA, inhibits replication and transcription and induces cell death. Carboplatin (NSC 241240) is a derivative of CDDP and a potent anti-cancer agent.

HY-Y1042S

4-Cyanophenol-d4
4-Cyanophenol-d₄ is the deuterium labeled 4-Cyanophenol[1].

HY-Y0226S1

NSC 1940-d8
NSC 1940-d₈ is the deuterium labeled NSC 1940[1].

HY-Y0226S2

NSC 1940-d4
NSC 1940-d₄ is the deuterium labeled NSC 1940[1].

HY-Y1675S

NSC 65593-d4
NSC 65593-d₄ is the deuterium labeled NSC 65593[1].

HY-B0246S4

Carbamazepine-d4
Carbamazepine-d4 (CBZ-d4; NSC 169864-d4) is the deuterium labeled Carbamazepine-d4 (HY-B0246S4) .

HY-N5034S

Phosphorylethanolamine-d4
Phosphorylethanolamine-d₄ (Monoaminoethyl phosphate-d₄; NSC 254167-d₄) is a deuterium labeled Phosphorylethanolamine (HY-N5034). Phosphorylethanolamine is an endogenous metabolite.

HY-79576S

NSC 88911-d3
NSC 88911-d₃ is the deuterium labeled NSC 88911[1].

HY-Y0093S

NSC 5416-d14
NSC 5416-d₁₄ is the deuterium labeled NSC 5416[1].

HY-Y0124S

NSC 16590-d6
NSC 16590-d₆ is the deuterium labeled NSC 16590. NSC 16590 inhibits the production of endogenous ethylene in the cotyledonary segments of cocklebur.

HY-B0217S

Nitazoxanide-d4
Nitazoxanide-d₄ is the deuterium labeled Nitazoxanide, which is an antiprotozoal agent.

HY-N1150S1

Thymidine-d4
Thymidine-d₄ is the deuterium labeled Thymidine. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication[1][2][3].

HY-100048S

Acetylisoniazid-d4
Acetylisoniazid-d₄ is the deuterium labeled Acetylisoniazid[1].

HY-Y0085S

NSC 190686-d3
NSC 190686-d₃ is the deuterium labeled NSC 190686[1].

HY-10844S1

Pretomanid-d5
Pretomanid-d₅ is deuterated labeled Pretomanid (HY-10844). Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 μg/mL.

HY-B0504S2

Creatinine-d5
Creatinine-d₅ is the deuterium labeled Creatinine. Creatinine (NSC13123) is a break-down product of creatine phosphate in muscle, and is usually produced at a fairly constant rate by the body.

HY-123533S

Resorufin-d6
Resorufin-d₆ is the deuterium labeled Resorufin. Resorufin (NSC 12097) is a highly fluorescent pink dye for the detection of ROS/RNS and a second analyte[1].

HY-W022039S

(Benzyloxy)benzene-d2
(Benzyloxy)benzene-d2 (NSC 77971-d2) is the deuterium labeled Benzyloxybenzene (HY-W022039) .

HY-B1944S

Dipropyl phthalate-d4
Dipropyl phthalate-d₄ is the deuterium labeled Dipropyl phthalate[1].

HY-B1556S

Benzyl salicylate-d4
Benzyl salicylate-d₄ is the deuterium labeled Benzyl salicylate[1].

HY-41680S

4-Aminobenzonitrile-d4
4-Aminobenzonitrile-d₄ is the deuterium labeled 4-Aminobenzonitrile[1].

HY-66005S

Acetaminophen-d4
Acetaminophen-d₄ is the deuterium labeled Acetaminophen. Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM; is a widely used antipyretic and analgesic agent[1][2][3]. Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor[4].

HY-N1150S10

Thymidine-d14
Thymidine-d₁₄ (DThyd-d₁₄; NSC 21548-d₁₄) is deuterium labeled Thymidine (HY-N1150). Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication.

HY-W016389S

9H-Fluoren-2-ol-d9
9H-Fluoren-2-ol-d₉ (NSC 31248-d₉) is a deuterium labeled compound.

HY-W779017

Thymidine-13C5
Thymidine- ¹³C₅ (DThyd- ¹³C₅; NSC 21548- ¹³C₅) is ¹³C-labeled Thymidine (HY-N1150) .

HY-B2150S

4-Hydroxyantipyrine-d3
4-Hydroxyantipyrine-d₃ is the deuterium labeled 4-Hydroxyantipyrine. 4-Hydroxyantipyrine is the major metabolite of Antipyrine, can be as a biodistribution promoter. 4-Hydroxyantipyrine can increase distribution of concentration ratio of Antipyrine in the brain[1][2][3].

HY-17413S2

Zidovudine-d4
Zidovudine-d₄ is deuterated labeled Zidovudine (HY-17413). Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection. Zidovudine increases CRISPR/Cas9-mediated editing frequency.

HY-B0094S3

Artemisinin-13C,d4

Artemisinin- ¹³C,d₄ is ¹³C and deuterated labeled Artemisinin (HY-B0094). Artemisinin (Qinghaosu), a sesquiterpene lactone, is an anti-malarial agent isolated from the aerial parts of Artemisia annua L. plants . Artemisinin inhibits AKT signaling pathway by decreasing pAKT in a dose-dependent manner. Artemisinin reduces cancer cell proliferation, migration, invasion, tumorigenesis and metastasis and has neuroprotective effects .

HY-Y0484S

1-Indanamine-d9 hydrochloride
1-Indanamine-d₉ (1-Aminoindan-d₉; 1-Aminoindane-d₉; NSC 186227-d₉; 1-Aminoindane-d₉) hydrochloride is deuterium-labeled 1-Indanamine hydrochloride (HY-Y0484) .

HY-Y0219S1

1,2,4-Triazole-d3
NSC 83128-d₃ is the deuterium labeled NSC 83128[1].

HY-B1008S

4-Aminobenzoic acid-d4
4-Aminobenzoic acid-d₄ is the deuterium labeled 4-Aminobenzoic acid. 4-Aminobenzoic acid is an intermediate in the synthesis of folate by bacteria, plants, and fungi.

HY-N0006S1

Demethoxycurcumin-d4
Demethoxycurcumin-d₄ is the deuterium labeled Demethoxycurcumin. Demethoxycurcumin (Curcumin II) is a major active curcuminoid; possess anti-inflammatory properties[1].

HY-N0055S

Chlorogenic acid-13C3

Chlorogenic acid- ¹³C₃ (Heriguard- ¹³C₃; NSC-407296- ¹³C₃) is ¹³C- and ¹⁵N-labeled Chlorogenic acid (HY-N0055). Chlorogenic acid is a major phenolic compound in Lonicera japonica Thunb.. It plays several important and therapeutic roles such as antioxidant activity, antibacterial, hepatoprotective, cardioprotective, anti-inflammatory, antipyretic, neuroprotective, anti-obesity, antiviral, anti-microbial, anti-hypertension .

HY-B0678S1

Metaxalone-d6

Metaxalone-d₆ is deuterium labeled Metaxalone. Metaxalone (AHR438; NSC170959) is an FDA-approved muscle relaxant. Metaxalone acts mainly on the central nervous system and achieves muscle relaxation by inhibiting polysynaptic reflex arcs. In addition, Metaxalone is an inhibitor of MAO-A, which has anti-inflammatory and antioxidant effects. Metaxalone inhibits IL-1β-induced inflammatory phenotype, modulates NF-κB and other related signaling pathways, and decreases MAO-A expression and activity in IL-1β-treated microglia .

HY-Y0251S

3-Nitrophthalic acid-d3
NSC 3120-d₃ is the deuterium labeled NSC 3120[1].

HY-B0329S

Isoniazid-d4
Isoniazid-d₄ is the deuterium labeled Isoniazid. Isoniazid (INH) is a proagent and must be activated by a bacterial catalase-peroxidase enzyme KatG. Isoniazid is bactericidal to rapidly dividing mycobacteria and has anti-tuberculostatic activity[1][2][3][4].

HY-118861S

Enclomiphene-d4 hydrochloride
Enclomiphene-d₄ (hydrochloride) is a deuterium labeled Enclomiphene. Enclomiphene-d₄ (hydrochloride) is a potent and orally active oestrogen receptor antagonist, with antioestrogenic property[1].

HY-109015S

Tucidinostat-d4
Tucidinostat-d₄ is the deuterium labeled Tucidinostat. Tucidinostat is a potent and orally bioavailable HDAC enzymes class I (HDAC1/2/3) and class IIb (HDAC10) inhibitor, with IC50s of 95, 160, 67 and 78 nM, respectively[1].

HY-19696AS

Tauroursodeoxycholate-d4 sodium
Tauroursodeoxycholate-d₄ (sodium) is the deuterium labeled Tauroursodeoxycholate sodium. Tauroursodeoxycholate (Tauroursodeoxycholic acid; TUDCA) sodium is an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12. Tauroursodeoxycholate also inhibits ERK.

HY-19696S1

Tauroursodeoxycholate-d4
Tauroursodeoxycholate-d₄ is deuterium labeled Tauroursodeoxycholate. Tauroursodeoxycholate (Tauroursodeoxycholic acid) is an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12. Tauroursodeoxycholate also inhibits ERK.

HY-B0389S24

D-Glucose-d4
D-Glucose-d₄ is the deuterium labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molec

HY-B0696AS

Tiagabine-d4 hydrochloride
Tiagabine-d₄ hydrochloride is deuterated labeled Tiagabine hydrochloride (HY-B0696A). Tiagabine hydrochloride is a potent and selective GABA reuptake inhibitor, used as an anticonvulsant agent, with IC₅₀s of 67, 446 and 182 nM for [ ³H]GABA uptake in Synaptosomes, Neurons and Glia, respectively .

HY-13273S

Ostarine-d4
Ostarine-d4 is a deuterated labeled Ostarine .

HY-Y0219S

1,2,4-Triazole-13C2,15N3
NSC 83128- ¹³C₂, ¹⁵N₃ is the ¹³C and ¹⁵N labeled NSC 83128[1].

HY-34498S

4-Chloro-2-methylphenol-d4
4-Chloro-2-methylphenol-d₄ is the deuterium labeled 4-Chloro-2-methylphenol[1].

HY-107542S

Oleoylethanolamide-d4
Oleoylethanolamide-d₄ is the deuterium labeled Oleoylethanolamide. Oleoylethanolamide is a high affinity endogenous PPAR-α agonist, which plays an important role in the treatment of obesity and arteriosclerosis.

HY-B0017S

Telbivudine-d4
Telbivudine-d₄ is deuterium labeled Telbivudine. Telbivudine (Epavudine), an orally active thymidine nucleoside analog, is a potent antiviral inhibitor of hepatitis B virus (HBV) replication[1].

HY-B0579S

Cyclosporin A-d4
Cyclosporin A-d₄ is the deuterium labeled Cyclosporin A. Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of calcineurin with an IC50 of 5 nM. Cyclosporin A also inhibits CD11a/CD18 ad

HY-16582AS

Sonidegib-d4
Sonidegib-d4 is a isotope of Sonidegib. Sonidegib is a potent and selective Smo antagonist with IC₅₀ of 1.3 nM and 2.5 nM for mouse and human Smo in binding assay, respectively .

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Species:	Human (13)
Tag:	GFP (3) His (12) Strep (5) Trx (1) Flag (7)
Source:	HEK293 (10) E. coli (3)


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NSC 1940-d<sub>4</sub>

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