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N-Desmethyl Rosuvastatin-d<sub>6</sub> disodium

" in MedChemExpress (MCE) Product Catalog:

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By Research Areas:	Cancer (809) Cardiovascular Disease (238) Endocrinology (193) Infection (417) Inflammation/Immunology (382) Metabolic Disease (440) Neurological Disease (415)
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2967

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Oligonucleotides

Targets Recommended: P-glycoprotein

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-70002AS

N-desmethyl Enzalutamide-d6 N-Desmethyl MDV 3100-d<sub>6sub>	Androgen Receptor	Cancer
N-desmethyl Enzalutamide-d₆ is a deuterium labeled N-desmethyl Enzalutamide. N-desmethyl Enzalutamide is an active metabolite of Enzalutamide. N-desmethyl Enzalutamide is the active metabolite of Enzalutamide. N-desmethyl Enzalutamide demonstrates primary and secondary pharmacodynamics of similar potency to Enzalutamide and circulates at approximately the same plasma concentrations as enzalutamide[1].

HY-12388AS

N-Desmethyl clomipramine-d3 hydrochloride Desmethylclomipramine-d<sub>3sub> (hydrochloride)；Norclomipramine-d<sub>3sub> hydrochloride	Drug Metabolite	Neurological Disease
N-Desmethyl Clomipramine-d₃ (hydrochloride) is the deuterium labeled N-Desmethyl Clomipramine. N-Desmethyl Clomipramine hydrochloride (Desmethylclomipramine hydrochloride) is a primary plasma N-desmethyl metabolite of Clomipramine[1]

HY-12388A

N-Desmethyl clomipramine hydrochloride Desmethylclomipramine hydrochloride; Norclomipramine hydrochloride	Drug Metabolite	Neurological Disease
N-Desmethyl Clomipramine hydrochloride (Desmethylclomipramine hydrochloride) is a primary plasma N-desmethyl metabolite of Clomipramine. Clomipramine is a tricyclic antidepressant .

HY-G0017S

N-Desmethyl imatinib-d8 Norimatinib-d<sub>8sub>; Imatinib metabolite N-Desmethyl imatinib-d<sub>8sub>	Drug Metabolite	Cancer
N-Desmethyl imatinib-d₈ is a deuterium labeled Imatinib metabolite N-Desmethyl Imatinib.

HY-Z3203S

**N-Desmethyl Rosuvastatin-d6 disodium**	Isotope-Labeled Compounds	Others
N-Desmethyl Rosuvastatin-d₆ (disodium) is the deuterium labeled N-Desmethyl Rosuvastatin disodium[1].

HY-G0017S1

N-Desmethyl imatinib-d4 Norimatinib-d<sub>4sub>; Imatinib metabolite N-Desmethyl imatinib-d<sub>4sub>	Isotope-Labeled Compounds	Others
N-Desmethyl imatinib-d₄ is the deuterium-labeled N-Desmethyl imatinib (HY-G0017). N-Desmethyl imatinib-d₄ (Norimatinib) is a metabolite of Imatinib (HY-15463). Imatinib is a multi-target inhibitor of v-Abl, c-Kit and PDGFR .

HY-W741626

N-Desmethyl selegiline-d5 (-)-N-Desmethylselegiline-d<sub>5sub>	Isotope-Labeled Compounds	Others
N-Desmethyl selegiline-d5 is the deuterium labeled N-Desmethyl selegiline .

HY-118788S

N-Desmethyl rosiglitazone-d4 SB 237216-d<sub>4sub>	Isotope-Labeled Compounds	Others
N-Desmethyl rosiglitazone-d₄ is the deuterium labeled N-Desmethyl rosiglitazone[1].

HY-118601S

N-Desmethyl Pirenzepine-d8 LS 822-d<sub>8sub>	Isotope-Labeled Compounds	Others
N-Desmethyl Pirenzepine-d₈ is the deuterium labeled N-Desmethyl Pirenzepine[1].

HY-108226S

*Regorafenib N-oxide and N-desmethyl* (M5)-d3** N-Desmethyl regorafenib N-oxide-d<sub>3sub>	Isotope-Labeled Compounds	Others
Regorafenib N-oxide and N-desmethyl (M5)-d₃ is deuterium labeled Regorafenib N-oxide and N-desmethyl (M5).

HY-160849

N-Desmethyl Rilmazolam	GABA Receptor	Others Metabolic Disease
N-desmethyl Rilmazolam, a triazolobenzodiazepine, serves as an analytical reference standard. N-desmethyl Rilmazolam is an active metabolite derived from rilmazafone (HY-106547). N-desmethyl Rilmazolam is designed for use in research and forensic settings .

HY-70002A

N-desmethyl Enzalutamide N-Desmethyl MDV 3100	Androgen Receptor	Cancer
N-desmethyl Enzalutamide is the active metabolite of Enzalutamide.N-desmethyl Enzalutamide is the active metabolite of Enzalutamide. N-desmethyl Enzalutamide demonstrates primary and secondary pharmacodynamics of similar potency to Enzalutamide and circulates at approximately the same plasma concentrations as enzalutamide .

HY-G0010

*Netupitant metabolite N-desmethyl* Netupitant** N-Desmethyl Netupitant	Drug Metabolite	Neurological Disease Metabolic Disease
N-desmethyl Netupitant is a metabolite of Netupitant, which is an antiemitic drug.

HY-150544S

N-Desmethyl selegiline-d5 hydrochloride (-)-N-Desmethylselegiline-d<sub>5sub> hydrochloride	Isotope-Labeled Compounds	Others
N-Desmethyl Selegiline-dd₅ hydrochloride is the deuterium labeled N-Desmethyl Selegiline hydrochloride[1]. N-Desmethyl Selegiline-d5 hydrochloride is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-117605R

N-Desmethyl Sildenafil (Standard)	Phosphodiesterase (PDE)	Cardiovascular Disease
N-Desmethyl Sildenafil (Standard) is the analytical standard of N-Desmethyl Sildenafil. This product is intended for research and analytical applications. N-Desmethyl Sildenafil (Desmethylsildenafil) is a major metabolite of Sildenafil. Sildenafil is a potent phosphodiesterase type 5 (PDE5) inhibitor .

HY-132685AS

N-Desmethyl Topotecan-d3 hydrochloride	Isotope-Labeled Compounds	Others
N-Desmethyl Topotecan-d3 hydrochloride is the deuterium labeled N-Desmethyl Topotecan hydrochloride .

HY-135392S

N-Desmethyl Pimavanserin-d9 hydrochloride AC-279-d<sub>9sub> hydrochloride	Isotope-Labeled Compounds	Neurological Disease
N-Desmethyl Pimavanserin-d9 hydrochloride (AC-279-d9 hydrochloride) is the deuterium labeled N-Desmethyl Pimavanserin (HY-135392). N-Desmethyl Pimavanserin is the active metabolite of Pimavanserin. Pimavanserin is a selective inverse agonist of the 5-HT2A receptor with pIC₅₀ and pK_d of 8.73 and 9.3, respectively .

HY-132626S

N-Desmethyl Tamoxifen-d5	Isotope-Labeled Compounds	Others
N-Desmethyl Tamoxifen-d₅ is the deuterium labeled N-Desmethyl Tamoxifen[1].

HY-141750S1

N-Desmethyl Zolmitriptan-d3	Isotope-Labeled Compounds	Others
N-Desmethyl Zolmitriptan-d₃ is the deuterium labeled N-Desmethyl Zolmitriptan[1].

HY-143922S

N-Desmethyl Bedaquiline-d6	Isotope-Labeled Compounds	Others
N-Desmethyl Bedaquiline-d₆ is the deuterium labeled N-Desmethyl Bedaquiline[1].

HY-132344S

N-Desmethyl asenapine-d4 hydrochloride	Isotope-Labeled Compounds	Others
N-Desmethyl asenapine-d₄ (hydrochloride) is the deuterium labeled N-Desmethyl asenapine hydrochloride[1].

HY-139519S

N-Desmethyl diphenhydramine-d3 hydrochloride	Histamine Receptor	Inflammation/Immunology
N-Desmethyl diphenhydramine-d₃ (hydrochloride) is the deuterium labeled N-Desmethyl diphenhydramine hydrochloride[1].

HY-G0010S

N-desmethyl Netupitant-d6	Isotope-Labeled Compounds Drug Metabolite	Neurological Disease Endocrinology
N-desmethyl Netupitant-d₆ is the deuterium labeled N-desmethyl Netupitant, which is a metabolite of Netupitant.

HY-144143S

N-Desmethyl Olopatadine-d3 hydrochloride	Isotope-Labeled Compounds	Others
N-Desmethyl Olopatadine-d₃ (hydrochloride) is the deuterium labeled N-Desmethyl Olopatadine hydrochloride[1].

HY-W741222S

N-Desmethyl Olopatadine-d6	Isotope-Labeled Compounds	Others
N-Desmethyl Olopatadine-d₆ is deuterium-labeled N-Desmethyl Olopatadine (HY-W741222) .

HY-W754151

N-Desmethyl apalutamide-d4	Isotope-Labeled Compounds	Others
N-Desmethyl apalutamide-d₄ is the deuterium-labeled N-Desmethyl-Apalutamide (HY-135331). N-Desmethyl Apalutamide is an active metabolite of Apalutamide. N-Desmethyl Apalutamide is a less potent antagonist of the androgen receptor and is responsible for one-third of the activity of Apalutamide. The formation of N-Desmethyl Apalutamide mediated predominantly by CYP2C8 and CYP3A4. N-Desmethyl Apalutamide is moderate to strong CYP3A4 and *CYP2B6* inducer and has an excellent plasma-proteins bound concentration .

HY-117605S

N-Desmethyl Sildenafil-d8 Desmethylsildenafil-d<sub>8sub>; UK-103,320-d<sub>8sub>	Phosphodiesterase (PDE) Isotope-Labeled Compounds	Neurological Disease Cancer
N-Desmethyl Sildenafil-d₈ is the deuterium labeled N-Desmethyl Sildenafil (HY-117605). N-Desmethyl Sildenafil is a major metabolite of Sildenafil. Sildenafil is a potent phosphodiesterase type 5 (PDE5) inhibitor[1][2][3].

HY-143810S

N-Desmethyl Mifepristone-d3	Isotope-Labeled Compounds	Others
N-Desmethyl Mifepristone-d₃ is the deuterium labeled N-Desmethyl Mifepristone[1]. N-Desmethyl Mifepristone-d3 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-143767S

N-Desmethyl Azelastine-d4-1	Isotope-Labeled Compounds	Others
N-Desmethyl Azelastine-d₄-1 is the deuterium labeled N-Desmethyl Azelastine[1].

HY-143931S

N-Desmethyl citalopram-d4 oxalate	Isotope-Labeled Compounds	Others
N-Desmethyl citalopram-d₄ (oxalate) is the deuterium labeled N-Desmethyl citalopram oxalate[1].

HY-12388AR

N-Desmethyl clomipramine hydrochloride (Standard) Desmethylclomipramine hydrochloride (Standard); Norclomipramine hydrochloride (Standard)	Drug Metabolite	Neurological Disease
N-Desmethyl Clomipramine (hydrochloride) (Standard) is the analytical standard of N-Desmethyl Clomipramine (hydrochloride). This product is intended for research and analytical applications. N-Desmethyl Clomipramine hydrochloride (Desmethylclomipramine hydrochloride) is a primary plasma N-desmethyl metabolite of Clomipramine. Clomipramine is a tricyclic antidepressant .

HY-G0017

N-Desmethyl imatinib Norimatinib; Imatinib metabolite N-Desmethyl imatinib	Drug Metabolite	Others
N-Desmethyl imatinib (Norimatinib) is a metabolite of Imatinib (HY-15463). Imatinib is a multi-target inhibitor of v-Abl, c-Kit and PDGFR .

HY-G0017A

N-Desmethyl imatinib mesylate Norimatinib mesylate; Imatinib metabolite N-Desmethyl imatinib mesylate	Drug Metabolite	Others
N-Desmethyl imatinib mesylate (Norimatinib mesylate) is a metabolite of Imatinib (HY-15463). Imatinib is a multi-target inhibitor of v-Abl, c-Kit and PDGFR .

HY-W295339S

N-Desmethyl venlafaxine-d3	Isotope-Labeled Compounds	Others
N-Desmethyl venlafaxine-d₃ is a deuterium labeled compound.

HY-100647S

N-Desmethyl Nefopam-d4 hydrochloride	Isotope-Labeled Compounds	Others
N-Desmethyl Nefopam-d₄ (hydrochloride) is deuterium labeled N-Desmethylnefopam (hydrochloride).

HY-120422S

N-Desmethyl Regorafenib-d3	Isotope-Labeled Compounds	Others
N-Desmethyl Regorafenib-d₃ is deuterium labeled BAY-751098.

HY-137580

N-Desmethyl Eletriptan	Others	Metabolic Disease
N-desmethyl Eletriptan is a metabolite of Eletriptan (HY-A0039). It is formed from eletriptan primarily by the cytochrome P450 (CYP) isoform CYP3A4 in human liver microsomes.

HY-144386S

N-Desmethyl L-ergothioneine methyl ester-d6	Isotope-Labeled Compounds	Others
N-Desmethyl L-ergothioneine methyl ester-d₆ is the deuterium labeled N-Desmethyl L-ergothioneine methyl ester[1].

HY-N7612

N-Desmethyl Galanthamine N-Norgalanthamine	Cholinesterase (ChE)	Others
N-Desmethyl Galanthamine is a metabolite of Galanthamine. Galanthamine is a potent acetylcholinesterase (AChE) inhibitor with an IC₅₀ of 500 nM .

HY-U00199S

N-Desmethyl zopiclone-d8	Isotope-Labeled Compounds Drug Metabolite	Neurological Disease
N-Desmethyl zopiclone-d₈ is deuterium labeled Norzopiclone. Norzopiclone is the inactive metabolite of Zopiclone. Norzopiclone has some anxiolytic properties.

HY-135392

N-Desmethyl Pimavanserin AC-279	Drug Metabolite	Neurological Disease
N-Desmethyl Pimavanserin is the active metabolite of Pimavanserin. Pimavanserin is a selective inverse agonist of the 5-HT2A receptor with pIC₅₀ and pK_d of 8.73 and 9.3, respectively.

HY-117605

N-Desmethyl Sildenafil Desmethylsildenafil; UK-103,320	Phosphodiesterase (PDE)	Cardiovascular Disease
N-Desmethyl Sildenafil (Desmethylsildenafil) is a major metabolite of Sildenafil. Sildenafil is a potent phosphodiesterase type 5 (PDE5) inhibitor .

HY-108226S1

*Regorafenib N-oxide and N-desmethyl* (M5)-13C6**	Isotope-Labeled Compounds	Others
Regorafenib N-oxide and N-desmethyl (M5)- ¹³C₆ is the ¹³C-labeled Regorafenib N-oxide and N-desmethyl (M5)[1].

HY-142283BS

N-Desmethyl dosimertinib-d5	EGFR	Cancer
N-Desmethyl dosimertinib-d₅ is the deuterium labeled Dosimertinib (HY-142283). Dosimertinib is a highly potent, selective, and orally active deuterated EGFR inhibiotor. Dosimertinib can be used for the research of non-small-cell lung cancer[1][2].

HY-W740014

N-Desmethyl Zolmitriptan 183C91; DZT	5-HT Receptor	Neurological Disease
N-Desmethyl Zolmitriptan (183C91; DZT) is the active metabolite of the serotonin (5-HT) receptor subtype 5-HT1B and 5-HT1D agonist Zolmitriptan (HY-B0229). N-Desmethyl Zolmitriptan (183C91; DZT) is an agonist of 5-HT1B receptors and induces constriction in isolated human cerebral arteries (EC50=100 nM).

HY-17504BS

Rosuvastatin-d3 sodium	HMG-CoA Reductase (HMGCR) Autophagy	Cardiovascular Disease Metabolic Disease
Rosuvastatin-d₃ (sodium) is deuterium labeled Rosuvastatin.

HY-17504BS1

Rosuvastatin-d6 sodium	HMG-CoA Reductase (HMGCR) Autophagy	Cardiovascular Disease Metabolic Disease
Rosuvastatin-d₆ (sodium) is deuterium labeled Rosuvastatin.

HY-17504S

Rosuvastatin-d6 calcium	Isotope-Labeled Compounds HMG-CoA Reductase (HMGCR) Autophagy	Cardiovascular Disease Metabolic Disease
Rosuvastatin-d₆ (calcium) is deuterium labeled Rosuvastatin.

HY-135331

N-Desmethyl-Apalutamide	Androgen Receptor Cytochrome P450	Cancer
N-Desmethyl Apalutamide is an active metabolite of Apalutamide. N-Desmethyl Apalutamide is a less potent antagonist of the androgen receptor and is responsible for one-third of the activity of Apalutamide. The formation of N-Desmethyl Apalutamide mediated predominantly by CYP2C8 and CYP3A4. N-Desmethyl Apalutamide is moderate to strong CYP3A4 and *CYP2B6* inducer and has an excellent plasma-proteins bound concentration .

HY-131527

Wy-45494 hydrochloride N-Desmethyl Venlafaxine hydrochloride; Wy 45494	Others	Metabolic Disease
Wy-45494 hydrochloride (N-Desmethyl Venlafaxine hydrochloride; Wy 45494) is a minor active metabolite of the selective norepinephrine and serotonin reuptake inhibitor (SNRI) venlafaxine. It is formed from venlafaxine via the cytochrome P450 (CYP) isomer CYP3A4.2. Wy-45494 hydrochloride inhibits norepinephrine and serotonin reuptake in rat synaptosomal preparations (IC₅₀s of 4.7 and 1.6 μM, respectively). In vivo, Wy-45494 hydrochloride reversed reserpine-induced hypothermia in mice at a minimum effective dose (MED) of 10 mg/kg.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N7612

N-Desmethyl Galanthamine N-Norgalanthamine	Alkaloids other families Classification of Application Fields Source classification Other Diseases Plants Disease Research Fields	Cholinesterase (ChE)
N-Desmethyl Galanthamine is a metabolite of Galanthamine. Galanthamine is a potent acetylcholinesterase (AChE) inhibitor with an IC₅₀ of 500 nM .

HY-125833

Alpha-Naphthoflavone 5+ Cited Publications	Flavonoids Flavones Source classification Indigofera heterantha Wall. ex Brand. Plants Compositae Disease Research Fields Cancer	Cytochrome P450 Aryl Hydrocarbon Receptor Apoptosis
Alpha-Naphthoflavone is an orally active flavonoid that is a potent, competitive inhibitor of aromatase< b>aromatase. < b > IC < sub > 50 < / sub > < / b > and < b > K < sub > I < / sub > < / b > value were 0.5 and 0.2 microns. Alpha-Naphthoflavone can inhibit cell proliferation and induce apoptosis .

HY-D0887

Disodium 5'-inosinate 1 Publications Verification IMP disodium salt; disodium inosinate	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Disease Research Fields Food Research	Biochemical Assay Reagents
Disodium 5'-inosinate (IMP disodium salt) is a nucleotide-based umami agent. Disodium 5'-inosinate can bind to umami receptors and stimulate taste nerves, allowing the brain to perceive umami. In addition, Disodium 5'-inosinate produces a transient behavioral excitement in mice .

HY-F0001

*NADH disodium* salt** 4 Publications Verification disodium NADH	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
NADH disodium salt (Disodium NADH) is an orally active reduced coenzyme. NADH disodium salt is a donor of ADP-ribose units in ADP-ribosylaton reactions and a precursor of cyclic ADP-ribose. NADH disodium salt plays a role as a regenerative electron donor in cellular energy metabolism, including glycolysis, β-oxidation and the tricarboxylic acid (TCA) cycle .

HY-100196A

*Pyrroloquinoline quinone disodium* salt** 3 Publications Verification PQQ disodium salt; Methoxatin disodium salt	Quinones Structural Classification Microorganisms Classification of Application Fields Source classification Benzene Quinones Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite
Pyrroloquinoline quinone disodium salt, a redox co-factor, is an anionic, redox-cycling orthoquinone. Pyrroloquinoline quinone disodium salt is isolated from cultures of methylotropic bacteria and tissues of mammals. Pyrroloquinoline quinone disodium salt is an essential nutrient for mammals and is important for immune function .

HY-16637D

Folic acid disodium 5+ Cited Publications Vitamin B9 disodium; Vitamin M disodium	Structural Classification Natural Products Neurological Disease Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite DNA/RNA Synthesis
Folic acid disodium (Vitamin B9 disodium; Vitamin M disodium) is an orally active disodium salt form of Folic acid (HY-16637) with an intrinsic dissolution rate (IDR) of 4.96·10 ⁵ g/s . Folic acid disodium serves as cofactor in single-carbon transfer reactions and exhibits protective effects against neural tube defects, ischemic events, and cancer. Folate acid disodium overload leads to impaired brain development in embryogenesis and promotes growth of precancerous altered cells. Folic acid deficiency leads to megaloblastic anemia .

HY-B0345A

*ATP disodium* salt** Maximum Cited Publications 72 Publications Verification Adenosine 5'-triphosphate disodium salt; disodium adenosine triphosphate	Structural Classification Natural Products Microorganisms other families Animals Classification of Application Fields Source classification Plants Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite
ATP disodium salt (Adenosine 5'-triphosphate disodium salt) is a central component of energy storage and metabolism in vivo, provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP disodium salt is an important endogenous signaling molecule in immunity and inflammation .

HY-W015410

Disodium succinate 5 Publications Verification	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Disodium succinate is an anti-anxiety agent with oral activity. Disodium succinate is the salt form of Succinic acid. Disodium succinate is an intermediate product of the tricarboxylic acid cycle. Disodium succinate is an important platform chemical. Disodium succinate can be used as surfactant, additive, ion chelating agent, flavoring agent and other applications in chemical, pharmaceutical and food fields .

HY-12388

N-Desmethyl clomipramine Desmethylclomipramine; Norclomipramine	Structural Classification Natural Products Source classification Endogenous metabolite	Drug Metabolite
Desmethylclomipramine (Norclomipramine) is a metabolite of Clomipramine (HY-B0457A) and can be used for neurological research .

HY-17556A

Folinic acid disodium Leucovorin disodium	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite Antifolate
Folinic acid (Leucovorin) disodium is a biological folic acid and is a forms of vitamin B9. Folinic acid disodium is generally administered along with Methotrexate (MTX) (HY-14519) as a rescue agent to decrease MTX-induced toxicity. Folinic acid disodium and Sfluorouracil adjuvant chemotherapy shows effective in colon carcinoma .

HY-W011152

2'-Deoxycytidine-5'-monophosphoric acid disodium dCMP disodium	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
2'-Deoxycytidine-5'-monophosphoric acid disodium (dCMP disodium) is an endogenous metabolite .

HY-W015410R

Disodium succinate (Standard)	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Endogenous Metabolite
Disodium succinate (Standard) is the analytical standard of Disodium succinate. This product is intended for research and analytical applications. Disodium succinate is an anti-anxiety agent with oral activity. Disodium succinate is the salt form of Succinic acid. Disodium succinate is an intermediate product of the tricarboxylic acid cycle. Disodium succinate is an important platform chemical. Disodium succinate can be used as surfactant, additive, ion chelating agent, flavoring agent and other applications in chemical, pharmaceutical and food fields .

HY-B2176A

*ATP disodium* trihydrate** Maximum Cited Publications 72 Publications Verification Adenosine-5'-triphosphate disodium trihydrate	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite
ATP disodium trihydrate (Adenosine 5'-triphosphate disodium trihydrate) is a central component of energy storage and metabolism in vivo. ATP disodium trihydrate provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP disodium trihydrate is an important endogenous signaling molecule in immunity and inflammation .

HY-W013159

2'-Deoxyguanosine 5'-monophosphate disodium 5′-dGMP disodium	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
2'-Deoxyguanosine 5'-monophosphate disodium (5′-dGMP disodium) is a mononucleotide having guanine as the nucleobase. 2'-Deoxyguanosine 5'-monophosphate disodium is a nucleic acid guanosine triphosphate (GTP) derivative .

HY-N7097

Sulbenicillin disodium	Infection Classification of Application Fields Disease Research Fields	Bacterial Antibiotic
Sulbenicillin disodium is the disodium salt of Sulbenicillin. Sulbenicillin is a Penicillin antibiotic with antibacterial activity against a number of mucoid and non-mucoid strains of Pseudomonas aeruginosa .

HY-100542

D-α-Hydroxyglutaric acid disodium 3 Publications Verification disodium (R)-2-hydroxyglutarate	Structural Classification Human Gut Microbiota Metabolites Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields Cancer	Reactive Oxygen Species ATP Synthase mTOR Endogenous Metabolite
D-α-Hydroxyglutaric acid disodium (Disodium (R)-2-hydroxyglutarate) is the principal metabolite accumulating in neurometabolic disease D-2-hydroxyglutaric aciduria. D-α-Hydroxyglutaric acid disodium is a weak competitive antagonist of α-ketoglutarate (α-KG) and inhibits multiple α-KG-dependent dioxygenases with a K_i of 10.87 mM. D-α-Hydroxyglutaric acid disodium increases reactive oxygen species (ROS) production. D-α-Hydroxyglutaric acid disodium binds and inhibits ATP synthase and inhibits mTOR signaling .

HY-F0001R

*NADH (disodium* salt) (Standard)**	Structural Classification Natural Products Source classification Endogenous metabolite	Endogenous Metabolite
NADH (disodium salt) (Standard) is the analytical standard of NADH (disodium salt). This product is intended for research and analytical applications. NADH disodium salt (Disodium NADH) is an orally active reduced coenzyme. NADH disodium salt is a donor of ADP-ribose units in ADP-ribosylaton reactions and a precursor of cyclic ADP-ribose. NADH disodium salt plays a role as a regenerative electron donor in cellular energy metabolism, including glycolysis, β-oxidation and the tricarboxylic acid (TCA) cycle .

HY-W010735R

*ATP disodium* salt hydrate (Standard)**	Structural Classification Microorganisms other families Animals Ketones, Aldehydes, Acids Source classification Plants Endogenous metabolite	Endogenous Metabolite
ATP (disodium salt hydrate) (Standard) is the analytical standard of ATP (disodium salt hydrate). This product is intended for research and analytical applications. ATP disodium salt hydrate (Adenosine 5'-triphosphatedisodium salt hydrate) is a central component of energy storage and metabolism in vivo, provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP disodium salt hydrate is an important endogenous signaling molecule in immunity and inflammation .

HY-W013100

Cytidine-5'-triphosphate disodium 2 Publications Verification Cytidine triphosphate disodium; 5'-CTP disodium	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Cytidine-5'-triphosphate disodium is an endogenous metabolite.

HY-D0885D

*Phosphocreatine disodium* hydrate**	Classification of Application Fields Animals Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Phosphocreatine disodium hydrate is an endogenous metabolite.

HY-12590

Glutathione oxidized disodium L-Glutathione oxidized disodium; GSSG disodium; Oxiglutatione disodium	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite Reactive Oxygen Species
Glutathione oxidized disodium is produced by the oxidation of glutathione which is a major intracellular antioxidant and detoxifying agent .

HY-16502

Crocetin disodium Transcrocetin disodium; trans-Crocetin disodium	Structural Classification Classification of Application Fields Terpenoids Source classification Diterpenoids Lridaceae Plants Crocus sativus L. Disease Research Fields Cancer	iGluR
Crocetin (Transcrocetin) disodium, extracted from saffron (Crocus sativus L.), acts as an NMDA receptor antagonist with high affinity.

HY-N1443

Demethylcantharidate disodium	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite Apoptosis
Demethylcantharidate disodium, an endogenous metabolite, induces apoptosis in hepatocellular carcinoma cells via ER stress. Demethylcantharidate disodium shows excellent anticancer activity against multiple types of cancer .

HY-113038A

α-Hydroxyglutaric acid disodium 2-Hydroxyglutarate disodium; 2-Hydroxyglutaric acid disodium; 2-Hydroxypentanedioic acid disodium	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields Cancer	Histone Demethylase Endogenous Metabolite
α-Hydroxyglutaric acid (2-Hydroxyglutarate) disodium is an α-hydroxy acid form of glutaric acid. α-Hydroxyglutaric acid disodium is a competitive inhibitor of multiple α-ketoglutarate-dependent dioxygenases, including histone demethylases and the TET family of 5-methlycytosine (5mC) hydroxylases .

HY-113149A

Argininosuccinic acid disodium	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite Reactive Oxygen Species
Argininosuccinic acid disodium participates in the fourth step of the urea cycle and is cleaved into arginine and fumarate by argininosuccinate lyase (ASL). Argininosuccinic acid disodium reduces reduced glutathione (GSH) concentrations and increases reactive oxygen species production in the cerebral cortex and striatum. Argininosuccinic acid disodium causes lipid peroxidation and protein oxidation and also induces oxidative stress in the developing rat brain .

HY-N11799

Neochilenin 3-O-Methylquercetin 4′-O-glucoside	Structural Classification Flavonoids Source classification Plants Compositae Other Flavonoids	Others
Neochilenin (3-O-Methylquercetin 4 '-O-glucoside) is a glycoside of 3-O-methylquercetin, which can be isolated from the sub-family Cereoideae (Cactaceae). .

HY-108213A

*Inosinic acid (disodium)(hydrate)(1:2:X)* 2 Publications Verification 5'-IMP (disodium)(hydrate)(1:2:X); IMP (disodium)(hydrate)(1:2:X); Inosine 5'-dihydrogen phosphate (disodium)(hydrate)(1:2:X)	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Inosinic acid (disodium)(hydrate)(1:2:X) (5'-IMP (disodium)(hydrate)(1:2:X)) is an endogenous metabolite.

HY-W010735

*ATP disodium* salt hydrate** Maximum Cited Publications 72 Publications Verification Adenosine 5'-triphosphate disodium salt hydrate	Structural Classification Microorganisms other families Animals Classification of Application Fields Ketones, Aldehydes, Acids Source classification Plants Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite
ATP disodium salt hydrate (Adenosine 5'-triphosphatedisodium salt hydrate) is a central component of energy storage and metabolism in vivo, provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP disodium salt hydrate is an important endogenous signaling molecule in immunity and inflammation .

HY-110382

Cyclic-di-GMP disodium 5 Publications Verification c-di-GMP disodium; cyclic diguanylate disodium; 5GP-5GP disodium	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Cancer	STING Endogenous Metabolite
Cyclic-di-GMP disodium is a STING agonist and a bacterial second messenger that coordinates different aspects of bacterial growth and behavior, including motility, virulence, biofilm formation, and cell cycle progression. Cyclic-di-GMP disodium has anti-cancer cell proliferation activity and also induces elevated CD4 receptor expression and cell cycle arrest. Cyclic-di-GMP disodium can be used in cancer research .

HY-D0199

Adenosine 5'-diphosphate disodium 1 Publications Verification	Cardiovascular Disease Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Adenosine 5'-diphosphate disodium is a nucleoside diphosphate. Adenosine 5'-diphosphate disodium is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate disodium is a platelet aggregation agent for hemostasis and the development and extension of arterial thrombosis .

HY-W010970

*5'-Guanylic acid disodium* salt** 1 Publications Verification 5'-GMP disodium salt; 5'-guanosine monophosphate disodium salt	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
5'-Guanylic acid disodium salt (5'-GMP disodium salt) is composed of guanine, ribose, and phosphate moieties and it is a nucleotide monomer in messenger RNA. Guanosine derivatives are involved in intracellular signal transduction and have been identified in repetitive genomic sequences in telomeres, in ribosomal DNA, immunoglobulin heavy‐chain switch regions, and in the control regions of proto-oncogenes .

HY-W779068

Chenodeoxycholic acid 3-sulfate disodium	Structural Classification Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields Steroids	Endogenous Metabolite
Chenodeoxycholic acid 3-sulfate disodium is a bile acid. Chenodeoxycholic acid 3-sulfate disodium level corresponds closely with the extent of hepatic dysfunction .

HY-112169A

10-Formyltetrahydrofolic acid disodium	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
10-Formyltetrahydrofolic acid disodium is a form of tetrahydrofolic acid that acts as a donor of formyl groups in anabolism. 10-Formyltetrahydrofolic acid disodium can be used as a substrate for formyltransferase reactions and is involved in the biosynthesis of purines .

HY-134433A

GDP-L-fucose disodium	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
GDP-L-fucose disodium is a nucleotide sugar that is a key substrate for the biosynthesis of fucose oligosaccharides. GDP-L-fucose disodium provides the fucose moiety for the oligosaccharides. The formation of GDP-L-fucose disodium occurs through two pathways, the major de novo metabolic pathway and the minor remedial metabolic pathway .

HY-128738R

*Thymidine-5'-monophosphate disodium* salt (Standard)**	Structural Classification Ketones, Aldehydes, Acids Endogenous metabolite	Endogenous Metabolite
Thymidine-5'-monophosphate (disodium) salt (Standard) is the analytical standard of Thymidine-5'-monophosphate (disodium) salt. This product is intended for research and analytical applications. Thymidine-5'-monophosphate disodium salt is an endogenous metabolite.

HY-W015114R

*L-2-Hydroxyglutaric acid disodium* (Standard)** (S)-2-Hydroxyglutaric acid disodium (Standard)	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Histone Demethylase Mitochondrial Metabolism Endogenous Metabolite
L-2-Hydroxyglutaric acid (disodium) (Standard) is the analytical standard of L-2-Hydroxyglutaric acid (disodium). This product is intended for research and analytical applications. L-2-Hydroxyglutaric acid disodium is an epigenetic modifier and putative oncometabolite in renal cancer. L-2-Hydroxyglutaric acid disodium can inhibit histone demethylases and hence promote histone methylation . L-2-Hydroxyglutaric acid inhibits mitochondrial creatine kinase (Mi-CK) activity with K_m and K_i of 2.52 mM and 11.13 mM, respectively .

HY-113066A

*Guanosine 5'-diphosphate disodium* salt** 2 Publications Verification GDP disodium salt	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite Potassium Channel
Guanosine 5'-diphosphate (GDP) disodium salt, a purine nucleoside diphosphate, is interconverted to guanosine by the action of exonucleotidase and phosphorylation of nucleoside to guanine. Guanosine 5'-diphosphate disodium salt activates adenosine 5'-triphosphate-sensitive K ⁺ channel and is used to study the kinetics and characteristics of GTPases such as those associated with G-protein coupled receptors (GPCR). Guanosine 5'-diphosphate disodium salt is a potential iron mobilizer, which prevents the Hepcidin (HY-P70400)-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Elevated levels of guanosine 5’-diphosphate are associated with the pathogenesis of neurological diseases. Guanosine 5'-diphosphate disodium salt is promising for the research of inflammation, such as anemia of inflammation (AI) .

HY-W010970R

*5'-Guanylic acid disodium* salt (Standard)**	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Endogenous Metabolite
5'-Guanylic acid (disodium salt) (Standard) is the analytical standard of 5'-Guanylic acid (disodium salt). This product is intended for research and analytical applications. 5'-Guanylic acid disodium salt (5'-GMP disodium salt) is composed of guanine, ribose, and phosphate moieties and it is a nucleotide monomer in messenger RNA. Guanosine derivatives are involved in intracellular signal transduction and have been identified in repetitive genomic sequences in telomeres, in ribosomal DNA, immunoglobulin heavy‐chain switch regions, and in the control regions of proto-oncogenes .

HY-108213AR

*Inosinic acid (disodium)(hydrate)(1:2:X) (Standard)*	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Endogenous Metabolite
Inosinic acid (disodium)(hydrate)(1:2:X) (Standard) is the analytical standard of Inosinic acid (disodium)(hydrate)(1:2:X). This product is intended for research and analytical applications. Inosinic acid (disodium)(hydrate)(1:2:X) (5'-IMP (disodium)(hydrate)(1:2:X)) is an endogenous metabolite.

HY-W013175R

*Uridine 5'-monophosphate (disodium* salt) (Standard)**	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Endogenous Metabolite
Uridine 5'-monophosphate (disodium salt) (Standard) is the analytical standard of Uridine 5'-monophosphate (disodium salt). This product is intended for research and analytical applications. Uridine 5'-monophosphate disodium salt is component used for RNA synthesis.

HY-D0885B

Phosphocreatine disodium 1 Publications Verification disodium creatine phosphate	Classification of Application Fields Source classification Metabolic Disease Amino acids Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Phosphocreatine disodium, one of organic compounds known as alpha amino acids and derivatives, is a substrate for the determination of creatine kinase and used to regenerate ATP during skeletal muscle contraction .

HY-114364

UDP-Galactose disodium	Structural Classification Natural Products Neurological Disease Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	P2Y Receptor Endogenous Metabolite
UDP-Galactose disodium is a natural agonist of the P2Y₁₄ receptor with an EC₅₀ of 0.67 μM for the hP2Y₁₄ receptor. UDP-Galactose disodium is a substrate for the transferase beta-1, 4 galactosyltransferase V (B4GALT5). In addition, UDP-Galactose disodium is required for the biosynthesis of several abundant glycoconjugates that form the surface glycocalyx of Leishmania major .

HY-N0666D

L-Aspartic aicd disodium disodium L-aspartate	Cardiovascular Disease Classification of Application Fields Source classification Amino acids Endogenous metabolite Disease Research Fields	Endogenous Metabolite
L-Aspartic acid disodium is an amino acid, can be used as a suitable proagent for colon-specific agent deliverly .

HY-W008940R

*Cytidine 5'-diphosphate disodium* salt (Standard)**	Structural Classification Natural Products Source classification Endogenous metabolite	Endogenous Metabolite
Cytidine 5'-diphosphate (disodium salt) (Standard) is the analytical standard of Cytidine 5'-diphosphate (disodium salt). This product is intended for research and analytical applications. Cytidine 5'-diphosphate (Cytidine) disodium salt is a nucleoside diphosphate that acts as a carrier for phosphorylcholine, diacylglycerol, and other molecules during phospholipid synthesis .

HY-N11287A

UDP-xylose disodium	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
UDP-xylose disodium is a natural product that could be isolated from Cryptococcus laurentii (N RRL Y-1401). UDP-xylose disodium is a sugar donor for the synthesis of glycoproteins, polysaccharides, various metabolites, and oligosaccharides in plants, vertebrates, and fungi ..

HY-N2021A

Phosphoramidon Disodium	Cardiovascular Disease Alkaloids Structural Classification Microorganisms Classification of Application Fields Source classification Disease Research Fields Indole Alkaloids Cancer	MMP Angiotensin-converting Enzyme (ACE) Neprilysin Endogenous Metabolite
Phosphoramidon Disodium, a microbial metabolite, is a specific metalloprotease thermolysin inhibitor with an IC₅₀ of 0.4 μg/mL. Phosphoramidon Disodium also inhibits endothelin-converting enzyme (ECE), neutral endopeptidase (NEP), and angiotensin-converting enzyme (ACE) with IC₅₀ values of 3.5, 0.034, and 78 μM, respectively .

HY-N7032

*Uridine 5′-diphosphoglucose disodium* salt** 5 Publications Verification UDP-D-Glucose disodium salt	Structural Classification Natural Products Source classification Endogenous metabolite	Endogenous Metabolite P2Y Receptor
Uridine 5’-diphosphoglucose (UDP-glucose) disodium salt, secreted by cardiomyocytes during ischemia and reperfu, is a potent agonist of the proinflammatory P2Y14 receptor. It acts an important role in the regulation of inflammation and neutrophil polarization in neutrophils. Uridine 5’-diphosphoglucose disodium salt is also the precursor of glucose-containing oligosaccharides, polysaccharides, glycoproteins, and glycolipids in animal tissues and in some microorganisms. Uridine 5’-diphosphoglucose disodium salt is promising for research in counteracting myocardial infarction/reperfusion (MIR)-induced inflammation in the heart tissue .

HY-F0002A

*NADP disodium* salt** 5+ Cited Publications disodium NADP	Structural Classification Microorganisms other families Animals Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Plants Disease Research Fields	Endogenous Metabolite
NADP disodium salt is the disodium salt form of NADP (HY-113325). NADP is a coenzyme involved in cellular electron transfer reactions in biological metabolism, which is alternately oxidized (NADP+) and reduced (NADPH), and can maintain cellular redox homeostasis and regulate many biological events, including cellular metabolism. NADPH is a universal electron donor that provides reducing ability for synthetic metabolic reactions and redox balance. NADPH plays a multifunctional role in regulating inflammation, redox homeostasis, and synthetic metabolism processes .

HY-126304

*β-Glycerophosphate disodium* salt hydrate** 5+ Cited Publications	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Phosphatase Endogenous Metabolite ERK
β-Glycerophosphate disodium salt pentahydrate is a bioactive endogenous metabolite and a phosphatase inhibitor. β-Glycerophosphate disodium salt pentahydrate plays an important role in inducing and maintaining osteoblast differentiation, mineral metabolism and signal transduction, and can be used as a drug carrier to form heat-sensitive hydrogels. β-Glycerophosphate disodium salt hydrate accelerates the calcification of vascular smooth muscle cells .

HY-W015883A

Fumaric acid disodium 1 Publications Verification	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Biochemical Assay Reagents Endogenous Metabolite
Fumaric acid disodium is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Cat. No.	Product Name	Chemical Structure

HY-70002AS

N-desmethyl Enzalutamide-d6

N-desmethyl Enzalutamide-d₆ is a deuterium labeled N-desmethyl Enzalutamide. N-desmethyl Enzalutamide is an active metabolite of Enzalutamide. N-desmethyl Enzalutamide is the active metabolite of Enzalutamide. N-desmethyl Enzalutamide demonstrates primary and secondary pharmacodynamics of similar potency to Enzalutamide and circulates at approximately the same plasma concentrations as enzalutamide[1].

HY-12388AS

N-Desmethyl clomipramine-d3 hydrochloride
N-Desmethyl Clomipramine-d₃ (hydrochloride) is the deuterium labeled N-Desmethyl Clomipramine. N-Desmethyl Clomipramine hydrochloride (Desmethylclomipramine hydrochloride) is a primary plasma N-desmethyl metabolite of Clomipramine[1]

HY-G0017S

N-Desmethyl imatinib-d8
N-Desmethyl imatinib-d₈ is a deuterium labeled Imatinib metabolite N-Desmethyl Imatinib.

HY-Z3203S

**N-Desmethyl Rosuvastatin-d6 disodium**
N-Desmethyl Rosuvastatin-d₆ (disodium) is the deuterium labeled N-Desmethyl Rosuvastatin disodium[1].

HY-G0017S1

N-Desmethyl imatinib-d4
N-Desmethyl imatinib-d₄ is the deuterium-labeled N-Desmethyl imatinib (HY-G0017). N-Desmethyl imatinib-d₄ (Norimatinib) is a metabolite of Imatinib (HY-15463). Imatinib is a multi-target inhibitor of v-Abl, c-Kit and PDGFR .

HY-W741626

N-Desmethyl selegiline-d5
N-Desmethyl selegiline-d5 is the deuterium labeled N-Desmethyl selegiline .

HY-118788S

N-Desmethyl rosiglitazone-d4
N-Desmethyl rosiglitazone-d₄ is the deuterium labeled N-Desmethyl rosiglitazone[1].

HY-118601S

N-Desmethyl Pirenzepine-d8
N-Desmethyl Pirenzepine-d₈ is the deuterium labeled N-Desmethyl Pirenzepine[1].

HY-108226S

*Regorafenib N-oxide and N-desmethyl* (M5)-d3**
Regorafenib N-oxide and N-desmethyl (M5)-d₃ is deuterium labeled Regorafenib N-oxide and N-desmethyl (M5).

HY-150544S

N-Desmethyl selegiline-d5 hydrochloride
N-Desmethyl Selegiline-dd₅ hydrochloride is the deuterium labeled N-Desmethyl Selegiline hydrochloride[1]. N-Desmethyl Selegiline-d5 hydrochloride is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-132685AS

N-Desmethyl Topotecan-d3 hydrochloride
N-Desmethyl Topotecan-d3 hydrochloride is the deuterium labeled N-Desmethyl Topotecan hydrochloride .

HY-135392S

N-Desmethyl Pimavanserin-d9 hydrochloride
N-Desmethyl Pimavanserin-d9 hydrochloride (AC-279-d9 hydrochloride) is the deuterium labeled N-Desmethyl Pimavanserin (HY-135392). N-Desmethyl Pimavanserin is the active metabolite of Pimavanserin. Pimavanserin is a selective inverse agonist of the 5-HT2A receptor with pIC₅₀ and pK_d of 8.73 and 9.3, respectively .

HY-132626S

N-Desmethyl Tamoxifen-d5
N-Desmethyl Tamoxifen-d₅ is the deuterium labeled N-Desmethyl Tamoxifen[1].

HY-141750S1

N-Desmethyl Zolmitriptan-d3
N-Desmethyl Zolmitriptan-d₃ is the deuterium labeled N-Desmethyl Zolmitriptan[1].

HY-143922S

N-Desmethyl Bedaquiline-d6
N-Desmethyl Bedaquiline-d₆ is the deuterium labeled N-Desmethyl Bedaquiline[1].

HY-132344S

N-Desmethyl asenapine-d4 hydrochloride
N-Desmethyl asenapine-d₄ (hydrochloride) is the deuterium labeled N-Desmethyl asenapine hydrochloride[1].

HY-139519S

N-Desmethyl diphenhydramine-d3 hydrochloride
N-Desmethyl diphenhydramine-d₃ (hydrochloride) is the deuterium labeled N-Desmethyl diphenhydramine hydrochloride[1].

HY-G0010S

N-desmethyl Netupitant-d6
N-desmethyl Netupitant-d₆ is the deuterium labeled N-desmethyl Netupitant, which is a metabolite of Netupitant.

HY-144143S

N-Desmethyl Olopatadine-d3 hydrochloride
N-Desmethyl Olopatadine-d₃ (hydrochloride) is the deuterium labeled N-Desmethyl Olopatadine hydrochloride[1].

HY-W741222S

N-Desmethyl Olopatadine-d6
N-Desmethyl Olopatadine-d₆ is deuterium-labeled N-Desmethyl Olopatadine (HY-W741222) .

HY-W754151

N-Desmethyl apalutamide-d4

N-Desmethyl apalutamide-d₄ is the deuterium-labeled N-Desmethyl-Apalutamide (HY-135331). N-Desmethyl Apalutamide is an active metabolite of Apalutamide. N-Desmethyl Apalutamide is a less potent antagonist of the androgen receptor and is responsible for one-third of the activity of Apalutamide. The formation of N-Desmethyl Apalutamide mediated predominantly by CYP2C8 and CYP3A4. N-Desmethyl Apalutamide is moderate to strong CYP3A4 and CYP2B6 inducer and has an excellent plasma-proteins bound concentration .

HY-117605S

N-Desmethyl Sildenafil-d8
N-Desmethyl Sildenafil-d₈ is the deuterium labeled N-Desmethyl Sildenafil (HY-117605). N-Desmethyl Sildenafil is a major metabolite of Sildenafil. Sildenafil is a potent phosphodiesterase type 5 (PDE5) inhibitor[1][2][3].

HY-143810S

N-Desmethyl Mifepristone-d3
N-Desmethyl Mifepristone-d₃ is the deuterium labeled N-Desmethyl Mifepristone[1]. N-Desmethyl Mifepristone-d3 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-143767S

N-Desmethyl Azelastine-d4-1
N-Desmethyl Azelastine-d₄-1 is the deuterium labeled N-Desmethyl Azelastine[1].

HY-143931S

N-Desmethyl citalopram-d4 oxalate
N-Desmethyl citalopram-d₄ (oxalate) is the deuterium labeled N-Desmethyl citalopram oxalate[1].

HY-W295339S

N-Desmethyl venlafaxine-d3
N-Desmethyl venlafaxine-d₃ is a deuterium labeled compound.

HY-100647S

N-Desmethyl Nefopam-d4 hydrochloride
N-Desmethyl Nefopam-d₄ (hydrochloride) is deuterium labeled N-Desmethylnefopam (hydrochloride).

HY-120422S

N-Desmethyl Regorafenib-d3
N-Desmethyl Regorafenib-d₃ is deuterium labeled BAY-751098.

HY-144386S

N-Desmethyl L-ergothioneine methyl ester-d6
N-Desmethyl L-ergothioneine methyl ester-d₆ is the deuterium labeled N-Desmethyl L-ergothioneine methyl ester[1].

HY-U00199S

N-Desmethyl zopiclone-d8
N-Desmethyl zopiclone-d₈ is deuterium labeled Norzopiclone. Norzopiclone is the inactive metabolite of Zopiclone. Norzopiclone has some anxiolytic properties.

HY-108226S1

*Regorafenib N-oxide and N-desmethyl* (M5)-13C6**
Regorafenib N-oxide and N-desmethyl (M5)- ¹³C₆ is the ¹³C-labeled Regorafenib N-oxide and N-desmethyl (M5)[1].

HY-142283BS

N-Desmethyl dosimertinib-d5
N-Desmethyl dosimertinib-d₅ is the deuterium labeled Dosimertinib (HY-142283). Dosimertinib is a highly potent, selective, and orally active deuterated EGFR inhibiotor. Dosimertinib can be used for the research of non-small-cell lung cancer[1][2].

HY-17504BS

Rosuvastatin-d3 sodium
Rosuvastatin-d₃ (sodium) is deuterium labeled Rosuvastatin.

HY-17504BS1

Rosuvastatin-d6 sodium
Rosuvastatin-d₆ (sodium) is deuterium labeled Rosuvastatin.

HY-17504S

Rosuvastatin-d6 calcium
Rosuvastatin-d₆ (calcium) is deuterium labeled Rosuvastatin.

HY-17504AS

Rosuvastatin-d3
Rosuvastatin-d₃ is a deuterium labeled Rosuvastatin. Rosuvastatin (ZD 4522) is a competitive HMG-CoA reductase inhibitor with an IC50 of 11 nM[1]. Rosuvastatin potently blocks human ether-a-go-go related gene (hERG) current with an IC50 of 195 nM, delayed cardiac repolarization, and thereby prolonged action potential durations (APDs) and corrected QT interval (QTc) intervals[2].

HY-135331S

N-Desmethyl-Apalutamide-15N,d4

N-Desmethyl-Apalutamide-15N,d4 is the ¹⁵N and deuterium labeled isotope of N-Desmethyl-Apalutamide (HY-135331). N-Desmethyl Apalutamide is an active metabolite of Apalutamide. N-Desmethyl Apalutamide is a less potent antagonist of the androgen receptor and is responsible for one-third of the activity of Apalutamide. The formation of N-Desmethyl Apalutamide mediated predominantly by CYP2C8 and CYP3A4. N-Desmethyl Apalutamide is moderate to strong CYP3A4 and CYP2B6 inducer and has an excellent plasma-proteins bound concentration .

HY-B0302AS

Etidronic acid-d3 disodium
Etidronic acid-d₃ (disodium) is the deuterium labeled Etidronic acid disodium[1].

HY-N7032S1

Uridine 5′-diphosphoglucose-13C6 disodium

Uridine 5′-diphosphoglucose- ¹³C₆ (disodium) is the ¹³C labeled Uridine 5′-diphosphoglucose disodium salt[1]. Uridine 5′-diphosphoglucose disodium salt (UDP-D-Glucose disodium salt) is the precursor of glucose-containing oligosaccharides, polysaccharides, glycoproteins, and glycolipids in animal tissues and in some microorganisms. Uridine-5′-diphosphoglucose is an agonist of the P2Y14 receptor, a neuroimmune system GPCR[2].

HY-128038S

N-Desmethyl-loperamide-d3
N-Desmethyl-loperamide-d₃ is the deuterium labeled N-Desmethyl-loperamide[1].

HY-132709S

N-Desmethyl-diltiazem-d4 hydrochloride
N-Desmethyl-diltiazem-d₄ (hydrochloride) is the deuterium labeled N-Desmethyl-diltiazem hydrochloride[1].

HY-113038AS1

α-Hydroxyglutaric acid-d4 disodium

α-Hydroxyglutaric acid-d₄ (disodium) is the deuterium labeled α-Hydroxyglutaric acid disodium[1]. α-Hydroxyglutaric acid (2-Hydroxyglutarate) disodium is an α-hydroxy acid form of glutaric acid. α-Hydroxyglutaric acid disodium is a competitive inhibitor of multiple α-ketoglutarate-dependent dioxygenases, including histone demethylases and the TET family of 5-methlycytosine (5mC) hydroxylases[2].

HY-144144S

*(E)-N-Desmethyl* Olopatadine-d3 hydrochloride**
(E)-N-Desmethyl Olopatadine-d₃ (hydrochloride) is the deuterium labeled (E)-N-Desmethyl Olopatadine.

HY-10820AS

Pemetrexed-d5 disodium
Pemetrexed-d₅ (disodium) is the deuterium labeled Pemetrexed disodium. Pemetrexed disodium (LY231514 disodium) is an antifolate, the Kis of the pentaglutamate of Pemetrexed disodium are 1.3, 7.2, and 65 nM for inhibits thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT), respectively[1].

HY-157207S

N-Desmethyl-Atomoxetine labeled-d5 hydrochloride
N-Desmethyl-Atomoxetine labeled-d5 hydrochloride is the deuterium labeled N-Desmethyl-Atomoxetine labeled hydrochloride .

HY-A0294AS

Ertapenem-d4 disodium
Ertapenem-d₄ (disodium) is deuterium labeled Ertapenem (disodium).

HY-143949S

*(Rac)-N-desmethyl* Dapoxetine-d7 hydrochloride**
(Rac)-N-desmethyl Dapoxetine-d7 hydrochloride is the deuterium labeled (Rac)-N-desmethyl Dapoxetine hydrochloride[1].

HY-113238AS

Lithocholic acid 3-sulfate-d4 disodium
Lithocholic acid 3-sulfate-d₄ (disodium) is the deuterium labeled Lithocholic acid 3-sulfate disodium[1].

HY-143834S

*O-Desacetyl-N-desmethyl* Diltiazem-d3**
O-Desacetyl-N-desmethyl Diltiazem-d₃ is the deuterium labeled O-Desacetyl-N-desmethyl Diltiazem[1].

HY-139689S

*rac-trans-N-Desmethyl* sertraline-d3 hydrochloride**
rac-trans-N-Desmethyl sertraline-d₃ (hydrochloride) is the deuterium labeled rac-trans-N-Desmethyl sertraline hydrochloride[1].

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