Search Result

Results for "

Ganglioside GM3-d<sub>5</sub> Bovine Milk

" in MedChemExpress (MCE) Product Catalog:

By Targets:	P-glycoprotein (13) 11β-HSD (3) 5 alpha Reductase (4) 5-HT Receptor (67) Acetolactate Synthase (ALS) (1) Acyltransferase (2) ADC Cytotoxin (13) Adenosine Receptor (8) Adrenergic Receptor (76) AIM2 (1) Akt (5) Aldehyde Dehydrogenase (ALDH) (1) Aldose Reductase (1) Amino Acid Derivatives (2) Aminopeptidase (1) AMPK (7) Amyloid-β (6) Anaplastic lymphoma kinase (ALK) (8) Androgen Receptor (22) Angiotensin Receptor (25) Angiotensin-converting Enzyme (ACE) (19) Antibiotic (174) Antifolate (6) AP-1 (1) Apelin Receptor (APJ) (2) Apical Sodium-Dependent Bile Acid Transporter (2) Apoptosis (239) Arp2/3 Complex (1) Aryl Hydrocarbon Receptor (5) ATM/ATR (1) ATP Citrate Lyase (2) ATP Synthase (1) Aurora Kinase (1) Autophagy (263) Bacterial (279) Bcl-2 Family (3) Bcr-Abl (10) BCRP (4) Beta-lactamase (2) Beta-secretase (1) Biochemical Assay Reagents (42) Bradykinin Receptor (4) Btk (4) c-Fms (2) c-Kit (15) c-Met/HGFR (5) Calcineurin (2) Calcium Channel (61) Cannabinoid Receptor (10) Carbonic Anhydrase (13) Casein Kinase (2) Caspase (6) CaSR (2) Cathepsin (2) CD47 (2) CD73 (1) CDK (12) CFTR (5) CGRP Receptor (1) Checkpoint Kinase (Chk) (1) Chloride Channel (2) Cholecystokinin Receptor (2) Cholinesterase (ChE) (19) CMV (2) Complement System (5) COMT (5) COX (66) CRFR (2) CRISPR/Cas9 (3) Cuproptosis (1) CXCR (1) Cyclophilin (2) Cytochrome P450 (27) Dengue virus (4) Deubiquitinase (1) Dihydroorotate Dehydrogenase (1) Dipeptidyl Peptidase (14) Disulfidptosis (4) DNA Alkylator/Crosslinker (8) DNA Methyltransferase (3) DNA/RNA Synthesis (74) Dopamine Receptor (43) Dopamine β-hydroxylase (3) Drug Metabolite (59) Drug-Linker Conjugates for ADC (6) DYRK (2) E1/E2/E3 Enzyme (2) EBI2/GPR183 (1) EGFR (20) Elastase (1) Endogenous Metabolite (801) Endothelin Receptor (3) Enterovirus (7) Epigenetic Reader Domain (2) ERK (8) Estrogen Receptor/ERR (40) Factor Xa (6) FAK (1) Farnesyl Transferase (1) Fatty Acid Synthase (FASN) (3) Ferroptosis (44) FGFR (12) FKBP (3) Flavivirus (10) FLT3 (7) Fluorescent Dye (6) Fungal (64) FXR (5) G protein-coupled Bile Acid Receptor 1 (2) GABA Receptor (29) Galectin (1) Gap Junction Protein (2) GCGR (6) GHSR (1) GLP Receptor (1) Glucocorticoid Receptor (26) Glucosidase (4) Glucosylceramide Synthase (GCS) (2) Glutathione Reductase (1) Glutathione S-transferase (1) GlyT (2) GnRH Receptor (5) GPR35 (1) GPR55 (2) GSK-3 (3) HBV (8) HCV (20) HCV Protease (3) HDAC (16) Hedgehog (3) Hexokinase (1) HIF/HIF Prolyl-Hydroxylase (2) Histamine Receptor (32) Histone Acetyltransferase (5) Histone Demethylase (4) Histone Methyltransferase (3) HIV (59) HIV Integrase (11) HIV Protease (8) HMG-CoA Reductase (HMGCR) (16) HSP (4) HSV (17) IGF-1R (3) iGluR (19) IKK (2) Imidazoline Receptor (3) Indoleamine 2,3-Dioxygenase (IDO) (1) Influenza Virus (30) Insulin Receptor (1) Integrin (1) Interleukin Related (7) IRE1 (1) Isotope-Labeled Compounds (2051) JAK (7) JNK (4) Keap1-Nrf2 (10) Ketohexokinase (2) Kinesin (1) Leukotriene Receptor (9) Ligands for E3 Ligase (6) Ligands for Target Protein for PROTAC (1) Liposome (5) Lipoxygenase (3) LPL Receptor (6) mAChR (35) MDM-2/p53 (3) MEK (3) Melanocortin Receptor (2) Melatonin Receptor (8) mGluR (8) MicroRNA (1) Microtubule/Tubulin (18) Mineralocorticoid Receptor (10) Mitochondrial Metabolism (7) Mitophagy (37) MMP (11) Molecular Glues (9) Monoamine Oxidase (13) Monoamine Transporter (1) mTOR (1) Myosin (6) Na+/K+ ATPase (5) nAChR (12) NADPH Oxidase (1) Necroptosis (1) Neprilysin (7) Neurokinin Receptor (3) Neuropeptide Y Receptor (1) NF-κB (37) NO Synthase (21) NOD-like Receptor (NLR) (3) Notch (6) Nuclear Hormone Receptor 4A/NR4A (2) Nucleoside Antimetabolite/Analog (57) Opioid Receptor (8) Orexin Receptor (OX Receptor) (3) Organoid (1) Orthopoxvirus (10) Oxidative Phosphorylation (1) P2X Receptor (1) P2Y Receptor (7) p38 MAPK (4) PAK (7) Parasite (72) PARP (4) PDGFR (19) PGC-1α (1) PGE synthase (3) Phosphatase (11) Phosphodiesterase (PDE) (23) Phospholipase (5) PI3K (3) PKA (2) PKC (10) Potassium Channel (25) PPAR (23) Progesterone Receptor (24) Prolyl Endopeptidase (PREP) (2) Prostaglandin Receptor (24) PROTAC Linkers (2) Protease Activated Receptor (PAR) (1) Proteasome (3) Proton Pump (22) PTHR (1) Raf (7) RAR/RXR (5) Ras (2) Reactive Oxygen Species (43) Renin (3) RET (6) Reverse Transcriptase (9) ROS Kinase (5) RSV (7) SARS-CoV (40) Ser/Thr Protease (5) Serotonin Transporter (24) SGLT (6) Sigma Receptor (1) Sirtuin (6) Small Interfering RNA (siRNA) (1) SOD (2) Sodium Channel (24) Src (5) STAT (5) STING (1) Syk (1) TAM Receptor (3) Tau Protein (1) TGF-beta/Smad (4) TGF-β Receptor (1) Thrombin (8) Thrombopoietin Receptor (3) Thymidylate Synthase (5) Thyroid Hormone Receptor (10) TNF Receptor (6) Toll-like Receptor (TLR) (5) TOPK (1) Topoisomerase (23) Trk Receptor (4) TRP Channel (14) Tyrosinase (6) VAP-1 (1) Vasopressin Receptor (1) VD/VDR (12) VEGFR (26) Virus Protease (13) Wee1 (1) Xanthine Oxidase (6) β-catenin (4) γ-secretase (1)
By Research Areas:	Cancer (797) Cardiovascular Disease (241) Endocrinology (208) Infection (450) Inflammation/Immunology (400) Metabolic Disease (428) Neurological Disease (437)
Click Chemistry:	Azide (3) Alkynes (14)
Oligonucleotides:	Nucleosides and their Analogs (3) Pegylated Lipids (4) Pre-designed siRNA Sets (1) Emulsifiers (1) siRNAs (1)

3347

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

109

Peptides

MCE Kits

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

2908

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Oligonucleotides

Targets Recommended: P-glycoprotein

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-114456

**Ganglioside GM3**	Others	Metabolic Disease
Ganglioside GM3 is a precursor of a-, b-, and c-series gangliosides, interacts with transmembrane receptors such as the epidermal growth factor and insulin receptors, and regulates receptor functions by creating a specialized lipid environment. Ganglioside GM3 is synthesized by GM3 synthase and can be used for the research of hypercholesterolemia .

HY-114456AS

Ganglioside GM3-d5 Bovine Milk ammonium salt	Isotope-Labeled Compounds	Others
Ganglioside GM3-d₅ (Bovine Milk ammonium salt) is deuterium labeled Ganglioside GM3 (Bovine Milk ammonium salt).

HY-152002S

Ganglioside GM3-d3 ammonium	Isotope-Labeled Compounds	Others
Ganglioside GM3-d3 ammonium is a deuterated labeled Ganglioside GM3 ammonium .

HY-114456S

Ganglioside GM3-d7	Isotope-Labeled Compounds Others	Metabolic Disease
Ganglioside GM3-d₇ is deuterium labeled Ganglioside GM3. Ganglioside GM3 is a precursor of a-, b-, and c-series gangliosides, interacts with transmembrane receptors such as the epidermal growth factor and insulin receptors, and regulates receptor functions by creating a specialized lipid environment. Ganglioside GM3 is synthesized by GM3 synthase and can be used for the research of hypercholesterolemia ^[3].

HY-125859B

Lactoperoxidase, bovine milk	Bacterial	Infection
Lactoperoxidase, bovine milk is an antimicrobial protein that belongs to the mammalian heme peroxidase family. Lactoperoxidase, bovine milk uses H₂O₂ to catalyze the oxidation of its preferred halide substrates including I ⁻, Br ⁻, F ⁻, or the pseudohalide SCN ⁻ .

HY-N10546A

Ganglioside GM1 (bovine) (ammonium)	Others	Neurological Disease
Ganglioside GM1 (bovine) ammonium is a member of the ganglioside family that can be used for neurological disease research. Ganglioside GM1 (bovine) ammonium is a functional tissue receptor for the Cholera Toxin1 .

HY-P2755A

Xanthine oxidase, bovine milk	Reactive Oxygen Species	Inflammation/Immunology Endocrinology
Xanthine oxidase, bovine milk is a xanthine oxidoreductase enzyme that generates reactive oxygen species (ROS), catalyzes the oxidation of hypoxanthine to xanthine, and further catalyzes the oxidation of xanthine to uric acid .

HY-W747599

Ganglioside GQ1b (bovine) (sodium) TetrasialoGanglioside GQ1b sodium	Others	Neurological Disease
Ganglioside GQ1b (bovine) sodium promotes neurite outgrowth during early neuronal differentiation. Ganglioside GQ1b (bovine) sodium controls the neuronal differentiation process in mESCs .

HY-N10511

*GM1a Ganglioside* oligosaccharide**	Others	Inflammation/Immunology
GM1a Ganglioside oligosaccharide is a semisynthetic form of ganglioside GM1. Ganglioside GM1 is the natural receptor for cholera toxin and plays an important role not only in general growth regulation but also in the coupling of hormone-induced responses .

HY-157343

GD3 Ganglioside	Apoptosis	Neurological Disease Cancer
GD3 Ganglioside is a prominent ganglioside of human melanoma. GD3 Ganglioside is an inducer of mitochondrial permeability. GD3 ganglioside directly targets mitochondria in a bcl-2-controlled fashion. GD3 ganglioside is rapidly synthesized from accumulated ceramide after the clustering of death-inducing receptors and triggers apoptosis .

HY-157343A

*GD3 Ganglioside* sodium**	Apoptosis	Neurological Disease Cancer
GD3 Ganglioside sodium is a prominent ganglioside of human melanoma. GD3 Ganglioside sodium is an inducer of mitochondrial permeability. GD3 ganglioside directly targets mitochondria in a bcl-2-controlled fashion. GD3 ganglioside is rapidly synthesized from accumulated ceramide after the clustering of death-inducing receptors and triggers apoptosis .

HY-10844S1

Pretomanid-d5 PA-824-d<sub>5sub>; (S)-PA 824-d<sub>5sub>	Antibiotic Bacterial Isotope-Labeled Compounds	Infection Cancer
Pretomanid-d₅ is deuterated labeled Pretomanid (HY-10844). Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 μg/mL.

HY-P10529

Ganglioside GM1-binding peptides p3	Trk Receptor	Infection
Ganglioside GM1-binding peptides p3 is a synthetic peptide that can specifically bind to the pentasaccharide part of GM1 ganglioside. The dynamic transformation of Ganglioside GM1-binding peptides p3 may play an important role in the function of GM1 as a multiple receptor, such as in the classical pathway of cholera toxin infection. Ganglioside GM1-binding peptides p3 can be used to study the interaction between GM1 and its ligands .

HY-RS13999

SUB1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SUB1 Human Pre-designed siRNA Set A contains three designed siRNAs for SUB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SUB1 Human Pre-designed siRNA Set A SUB1 Human Pre-designed siRNA Set A

HY-146227

DNA topoisomerase II inhibitor 1	Topoisomerase Apoptosis	Cancer
DNA topoisomerase II inhibitor 1 (compound 8ed) is a potent DNA topoisomerase II inhibitor. DNA topoisomerase II inhibitor 1 shows anti-proliferative activity. DNA topoisomerase II inhibitor 1 induces apoptosis and cell cycle arrest at sub G1 phase .

HY-W747597

Ganglioside GD1b Disodium Salt (Bovine Brain) DisialoGanglioside GD1b; Ganglioside C1; Ganglioside G2	Endogenous Metabolite	Cardiovascular Disease
Ganglioside GD1b is an acidic glycosphingolipid that contains two sialic acid residues linked to an inner galactose unit. It is a component of plasma membranes where it packs densely with cholesterol to form lipid microdomains that modulate both intra- and intercellular signaling events. The concentration of ganglioside GD1b in human brain increases with age, constituting 7.85% of total sialic acid in the brain of 0- to 10-year-old subjects and 20.29% in 11- to 30-year-old subjects.2 Ganglioside GD1b levels are positively correlated with pilocytic astrocytoma tumor grade, and GD1b has been detected in various other gliomas, including primitive neuroectodermal tumors, glioblastomas, and anaplastic astrocytomas.3 This product contains ganglioside GD1b molecular species with primarily C18:0 fatty acyl chain lengths.

HY-B2167S

Docosahexaenoic acid-d5 DHA-d<sub>5sub>; Cervonic acid-d<sub>5sub>	Endogenous Metabolite	Neurological Disease
Docosahexaenoic acid-d₅ is the deuterium labeled Docosahexaenoic Acid. Docosahexaenoic Acid (DHA) is an omega-3 fatty acid abundantly present brain and retina. It can be obtained directly from fish oil and maternal milk.

HY-N13245

Milk Thistle Extract	Others	Others
Milk Thistle Extract is the extract of Milk Thistle, with content of 80% Silymarin.

HY-P3021

*Human milk* lysozyme**	Bacterial Biochemical Assay Reagents	Infection
Human milk lysozyme is the lysozyme found in human milk. Human milk lysozyme is thought to be a key defense factor in protecting the gastrointestinal tract of newborns against bacterial infection .

HY-N10546

Ganglioside GM1	Others	Neurological Disease
Ganglioside GM1 is a member of the ganglioside family that can be used for neurological disease research. Ganglioside GM1 is a functional tissue receptor for the Cholera Toxin1 .

HY-109037S3

Mavacamten-d5 MYK461-d<sub>5sub>; SAR439152-d<sub>5sub>	Isotope-Labeled Compounds Myosin	Cardiovascular Disease
Mavacamten-d₅ (MYK461-d₅; SAR439152-d₅) is deuterium labeled Mavacamten (HY-109037). Mavacamten (MYK461) is an orally active modulator of cardiac myosin, with IC₅₀s of 490, 711 nM for bovine cardiac and human cardiac, respectively.

HY-NP018

Bovine fibrinogen (from plasma) FGA; FGA protein	NF-κB	Inflammation/Immunology
Bovine fibrinogen (from fibrinogen) is a native fibrinogen from bovine plasma. Bovine fibrinogen (from fibrinogen) can regulate the activation of NF-KB in endothelial cells and upregulate the expression of inflammatory chemokines MCP-1 .

HY-148385

Ganglioside GM2	Others	Cancer
Ganglioside GM2 is a human tumor antigen (OFA-I-1). Ganglioside GM2 is the major lysosomal storage compound of Tay-Sachs disease .

HY-W010248S

2-Phenylglycine-d5 DL-α-Phenylglycine-d<sub>5sub>	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
2-Phenylglycine-d₅ is the deuterium labeled 2-Phenylglycine. 2-Phenylglycine (DL-α-Phenylglycine) is a metabolite in breast milk during the W2 to W4 lactation period[1].

HY-14566S1

Donepezil-d5 E2020-d<sub>5sub>	Cholinesterase (ChE)	Neurological Disease
Donepezil-d₅ is deuterium labeled Donepezil. Donepezil (E2020 free base) is a specific and potent AChE inhibitor with IC50s of 8.12 nM and 11.6 nM for bovine AChE and human AChE, respectively[1].

HY-NP001

*Cationic Bovine* Serum Albumin** Cationic Bovine Serum Albumin	Biochemical Assay Reagents	Neurological Disease
Cationic Bovine Serum Albumin is a 583 amino acid protein consisting of three homologous full alpha structural domains. Cationic Bovine Serum Albumin has remarkable neuroprotective effects on ischemic stroke when in combination with Tanshinone IIA (HY-N0135) .

HY-131139

Ganglioside GD3 disodium salt	Apoptosis	Neurological Disease Cancer
Ganglioside GD3 disodium salt is an acidic glycosphingolipid. Ganglioside GD3 disodium salt inhibits the proliferation of cancer cells, affects the opening of the mitochondrial permeability transition pore (PTPC), induces apoptosis and activates caspase family. Ganglioside GD3 disodium salt can be used in research about cancer and neurodegenerative diseases .

HY-131139A

Ganglioside GD3 diammonium	Apoptosis	Neurological Disease Cancer
Ganglioside GD3 diammonium is an acidic glycosphingolipid. Ganglioside GD3 diammonium inhibits the proliferation of cancer cells, affects the opening of the mitochondrial permeability transition pore (PTPC), induces apoptosis and activates caspase family. Ganglioside GD3 diammonium can be used in research about cancer and neurodegenerative diseases .

HY-B1374S1

Florfenicol-d3 (-)-Florfenicol-d<sub>3sub>; SCH-25298-d<sub>3sub>	Isotope-Labeled Compounds Bacterial Antibiotic	Infection
Florfenicol-d₃ is the deuterium labeled Florfenicol. Florfenicol, a commonly used veterinary antibiotic, is currently indicated for bovine respiratory disease, and also used in aquaculture for the control of enteric septicemia in catfish. Florfenicol can induce early embryonic death in eggs, with an LC50 of 1.07 μg/g.

HY-P3607

GHRF, bovine bGRF(1-44)-NH2	GHSR	Endocrinology
GHRF, bovine (bGRF(1-44)-NH2) is the bovine growth hormone (GH)-releasing factor (GHRF). GHRF, bovine increases the release of bovine GH, and shows a synergistic effect with Hydrocortisone (HY-N0583) .

HY-165740

Ganglioside GD2 DisialoGanglioside GD2	Others	Cancer
Ganglioside GD2, a member of the ganglioside family, is a tumor-associated antigen that is highly expressed in almost all neuroblastomas, as well as in most melanomas and retinoblastomas. Ganglioside GD2 contributes to tumor development by enhancing cell proliferation, motility, migration, adhesion, and invasion. Anti-Ganglioside GD2 strategies hold promise for research in the field of anti-tumor therapy .

HY-P5603

Bovine neutrophil beta-defensin 12 BNBD-12	Bacterial	Infection
Bovine neutrophil beta-defensin 12 is an antimicrobial peptide derived from bovine neutrophils, which has antibacterial activity against Escherichia coli and Staphylococcus aureus .

HY-146876S

*C18:0 GM1 Ganglioside-d5 ammonium*	Isotope-Labeled Compounds	Others
C18:0 GM1 Ganglioside-d₅ (ammonium) is deuterium labeled C18:0 GM1 Ganglioside (ammonium).

HY-W714151

Ganglioside ga1 Gg4cer; AsialoGanglioside GM1; Asialo GM1, Gangliotetraosylceramide; Asialo Ganglioside GM1a [...]; Ganglio-n-tetraosylceramide; Asialo GM1 Ganglioside; AsialoGanglioside gt1b	Others	Metabolic Disease
Ganglioside ga1 (Gg4cer; Asialoganglioside gm1; Asialo gm1, Gangliotetraosylceramide; Asialo ganglioside gm1a [...]; Ganglio-n-tetraosylceramide; Asialo gm1 ganglioside; Asialoganglioside gt1b) is an ester product.

HY-165136

Sphingomyelins, milk SMs (butterMilk)	Others	Others
Sphingomyelins, milk (SMs (buttermilk)) are compounds studied in sphingolipids, which play important roles in various biological processes.

HY-P3976

Lactalbumin B (50-53) Alpha [Lactorphin Alpha], bovine	Angiotensin-converting Enzyme (ACE)	Cardiovascular Disease
Lactalbumin B (50-53) Alpha [Lactorphin Alpha], bovine is a blood pressure lowering peptide containing 4 amino acids. Lactalbumin B (50-53) Alpha [Lactorphin Alpha], bovine is an angiotensin-converting Enzyme (ACE) inhibitor. Lactalbumin B (50-53) Alpha [Lactorphin Alpha], bovine can be used in research of high blood pressure .

HY-E70043

Ganglioside sialidase (AuSialidase S) Sialidase isoenzyme S; AuSialidase S	Endogenous Metabolite	Metabolic Disease
Ganglioside sialidase (AuSialidase S) is an endogenous metabolite. Ganglioside sialidases have been implicated in neuronal differentiation processes, including neurite outgrowth .

HY-E70073

Ganglioside sialidase (AuSialidase M2) Sialidase isoenzyme M2; AuSialidase M2	Others	Others
Ganglioside sialidase (AuSialidase M2) from Arthrobacter ureafaciens. Ganglioside sialidase is a highly specific N-acetylneuraminidase. Ganglioside sialidase can hydrolyze the internal sialic acid of GM1 under optimal condition with sodium cholate .

HY-W012481S

Nirvanol-d5 Ethylphenylhydantoin-d<sub>5sub>; Phenylethyihydantoin-d<sub>5sub>; Desmethylmephenytoin-d<sub>5sub>	Isotope-Labeled Compounds	Others
Nirvanol-d₅ is deuterium labeled Nirvanol.

HY-B0184S1

Felbamate-d5 Felbamyl-d<sub>5sub>; Felbatol-d<sub>5sub>; Taloxa-d<sub>5sub>	iGluR	Neurological Disease
Felbamate-d₅ is the deuterium labeled Felbamate[1]. Felbamate (W-554) is a potent nonsedative anticonvulsant whose clinical effect may be related to the inhibition of N-methyl-D-aspartate (NMDA)[2][3].

HY-U00315S

Gidazepam-d5 Gidasepam-d<sub>5sub>; Hidazepam-d<sub>5sub>; Hydazepam-d<sub>5sub>	GABA Receptor	Neurological Disease
Gidazepam-d5 is a deuterium labeled Gidazepam. Gidazepam is an agonist of GABA receptor channels (GABA RCs), and has anticonvulsant effect .

HY-16560S

Camptothecin-d5 Campathecin-d<sub>5sub>; (S)-(+)-Camptothecin-d<sub>5sub>; CPT-d<sub>5sub>	Topoisomerase ADC Cytotoxin MicroRNA Influenza Virus Apoptosis Fungal Antibiotic	Infection Cancer
Camptothecin-d₅ is the deuterium labeled Camptothecin. Camptothecin (CPT), a kind of alkaloid, is a DNA topoisomerase I (Topo I) inhibitor with an IC50 of 679 nM[1]. Camptothecin (CPT) exhibits powerful antineoplastic activity against colorectal, breast, lung and ovarian cancers, modulates hypoxia-inducible factor-1α (HIF-1α) activity by changing microRNAs (miRNA) expression patterns in human cancer cells[2][3].

HY-B0715S2

Pentoxifylline-d5 BL-191-d<sub>5sub>; PTX-d<sub>5sub>; Oxpentifylline-d<sub>5sub>	Phosphodiesterase (PDE) Autophagy HIV	Cardiovascular Disease Cancer
Pentoxifylline-d₅ is the deuterium labeled Pentoxifylline. Pentoxifylline (BL-191), a haemorheological agent, is an orally active non-selective phosphodiesterase (PDE) inhibitor, with immune modulation, anti-inflammatory, hemorheological, anti-fibrinolytic and anti-proliferation effects. Pentoxifylline can be used for the research of peripheral vascular disease, cerebrovascular disease and a number of other conditions involving a defective regional microcirculation[1][2][3].

HY-W127461

Ganglioside GM2, Asialo Gangliotriosylceramide	Biochemical Assay Reagents	Others
Ganglioside GM2 asialo (asialo-GM2) is a glycosphingolipid containing three monosaccharide residues and one fatty acid of variable chain length, but lacks the sialic acid residue present on ganglioside M2. Asialo-GM2 is found at low or undetectable levels in normal human brains, but it accumulates in the brains of patients with Tay-Sachs disease and Sandhoff disease, which are expressed as lysosomal β- A neurodegenerative disorder characterized by hexosaminidase A and B deficiency. It also binds to various bacteria, including Pseudomonas isolated from cystic fibrosis patients. The Asialo-GM2 mixture contains ganglioside GM2 asialo molecular species with fatty acyl chains of variable length.

HY-107819S

5α-Cholestan-3β-ol-d5 Dihydrocholesterol-d<sub>5sub>; 5α-Cholestanol-d<sub>5sub>; NSC 18188-d<sub>5sub>	Isotope-Labeled Compounds Endogenous Metabolite	Others
5α-Cholestan-3β-ol-d₅ is the deuterium labeled 5α-Cholestan-3β-ol. 5α-Cholestan-3β-ol is a derivitized steroid compound[1].

HY-N0573S

Umbelliferone-d5 7-Hydroxycoumarin-d<sub>5sub>; Hydrangin-d<sub>5sub>; NSC 19790-d<sub>5sub>	Endogenous Metabolite Apoptosis	Cancer
Umbelliferone-d₅ is the deuterium labeled Umbelliferone. Umbelliferone (7-Hydroxycoumarin), a natural product of the coumarin family, is a fluorescing compound which can be used as a sunscreen agent.

HY-W022036S

2-Ethoxyphenol-d5 Guaethol-d<sub>5sub>; Guethol-d<sub>5sub>; NSC 180-d<sub>5sub>	Isotope-Labeled Compounds	Others
2-Ethoxyphenol-d₅ is the deuterium labeled 2-Ethoxyphenol[1].

HY-66005S5

Acetaminophen-d5 Paracetamol-d<sub>5sub>; 4-Acetamidophenol-d<sub>5sub>; 4'-Hydroxyacetanilide-d<sub>5sub>	Isotope-Labeled Compounds	Others
Acetaminophen-d₅ is deuterated-labeled Acetaminophen.

HY-16562AS

Irinotecan-d5 hydrochloride (+)-Irinotecan-d<sub>5sub> hydrochloride; CPT-11-d<sub>5sub> hydrochloride; VAL-413-d<sub>5sub>	Autophagy Topoisomerase Isotope-Labeled Compounds	Cancer
Irinotecan-d₅ hydrochloride is deuterated labeled Irinotecan hydrochloride (HY-16562A). Irinotecan hydrochloride ((+)-Irinotecan hydrochloride) is a topoisomerase I inhibitor mainly used to treat colon cancer and rectal cancer .

HY-B0828S

Triazophos-d5 Hostathion 40EC-d<sub>5sub>; Hostathion-d<sub>5sub>; Hostation-d<sub>5sub>	Isotope-Labeled Compounds	Others
Triazophos-d5 is the deuterium labeled Triazophos(HY-B0828) .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N10546

Ganglioside GM1	Structural Classification Natural Products Animals	Others
Ganglioside GM1 is a member of the ganglioside family that can be used for neurological disease research. Ganglioside GM1 is a functional tissue receptor for the Cholera Toxin1 .

HY-125833

Alpha-Naphthoflavone 5+ Cited Publications	Flavonoids Flavones Source classification Indigofera heterantha Wall. ex Brand. Plants Compositae Disease Research Fields Cancer	Cytochrome P450 Aryl Hydrocarbon Receptor Apoptosis
Alpha-Naphthoflavone is an orally active flavonoid that is a potent, competitive inhibitor of aromatase< b>aromatase. < b > IC < sub > 50 < / sub > < / b > and < b > K < sub > I < / sub > < / b > value were 0.5 and 0.2 microns. Alpha-Naphthoflavone can inhibit cell proliferation and induce apoptosis ^[3] .

HY-P2352

*Fetuin, Fetal Bovine* Serum** 2 Publications Verification	Natural Products Animals Source classification Metabolic Disease Disease Research Fields	Others
Fetuin, Fetal Bovine Serum is a liver-secreted 64 kDa plasma glycoprotein isolated from fetal bovine serum. Fetuin, Fetal Bovine Serum inhibits trypsin activity and promote cellular attachment, growth, and differentiation .

HY-134238

*Cardiolipin (Heart, Bovine) (sodium)*	Structural Classification Natural Products Neurological Disease Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Cardiolipin (Heart, Bovine) sodium is a mitochondria-exclusive phospholipid. Cardiolipin (Heart, Bovine) sodium has the potential for the research of Neurological Disease .

HY-N10511

*GM1a Ganglioside* oligosaccharide**	Structural Classification Natural Products Polysaccharides Classification of Application Fields Endogenous metabolite Inflammation/Immunology Disease Research Fields Saccharides	Others
GM1a Ganglioside oligosaccharide is a semisynthetic form of ganglioside GM1. Ganglioside GM1 is the natural receptor for cholera toxin and plays an important role not only in general growth regulation but also in the coupling of hormone-induced responses .

HY-N12073

Monofucosyllacto-N-hexaose I MFLNH I	Structural Classification Polysaccharides Animals Source classification Saccharides	Others
Monofucosyllacto-N-hexaose I (MFLNH I) is a composition of human milk oligosaccharide .

HY-N10532

Lacto-N-difucohexaose II LNDFH II ; Lacto-N-fucohexaose	Structural Classification Polysaccharides Classification of Application Fields Animals Other Diseases Disease Research Fields Saccharides	Others
Lacto-N-difucohexaose II (LNDFH II) is one of the oligosaccharides in human milk, it is important for infant health .

HY-P1508

Bactenecin Bactenecin, Bovine	Infection Structural Classification Animals Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Disease Research Fields Other Antibiotics	Bacterial Fungal Antibiotic
Bactenecin (Bactenecin, bovine) is a potent 12-aa looped antimicrobial peptide isolated from bovine neutrophils. Bactenecin inhibits the growth of bacteria and yeast, and kills the fungus Trichophyton rubrum. Bactenecin increass membrane permeability, inhibits the growth and biofilm formation of *B. pseudomallei* ^[3].

HY-N11799

Neochilenin 3-O-Methylquercetin 4′-O-glucoside	Structural Classification Flavonoids Source classification Plants Compositae Other Flavonoids	Others
Neochilenin (3-O-Methylquercetin 4 '-O-glucoside) is a glycoside of 3-O-methylquercetin, which can be isolated from the sub-family Cereoideae (Cactaceae). .

HY-N10529

Lacto-N-fucopentaose V LNFP V	Structural Classification Natural Products Polysaccharides Classification of Application Fields Animals Other Diseases Disease Research Fields Saccharides	Others
Lacto-N-fucopentaose V (LNFP V), a new pentasaccharide, is an oligosaccharide found in human milk and other biofluids .

HY-W016979

δ-Decalactone	Natural Products Microorganisms Classification of Application Fields Source classification Other Diseases Rosaceae Plants Disease Research Fields Amygdalus persica L.	Others
δ-Decalactone is a lactone compound found in nonfat dry milks and fruit. δ-Decalactone has a sweet taste .

HY-N12074

Monofucosyllacto-N-hexaose III MFLNH III	Structural Classification Polysaccharides Classification of Application Fields Animals Source classification Other Diseases Disease Research Fields Saccharides	Others
Monofucosyllacto-N-hexaose III (MFLNH III) is a kind of neutral human milk oligosaccharides (HMO) .

HY-P1508A

Bactenecin TFA Bactenecin, Bovine TFA	Infection Natural Products Classification of Application Fields Animals Source classification Disease Research Fields	Bacterial Fungal
Bactenecin TFA (Bactenecin, bovine TFA) is a potent 12-aa looped antimicrobial peptide isolated from bovine neutrophils. Bactenecin TFA inhibits the growth of bacteria and yeast, and kills the fungus Trichophyton rubrum. Bactenecin TFA increass membrane permeability, inhibits the growth and biofilm formation of *B. pseudomallei* ^[3].

HY-W010248

2-Phenylglycine DL-α-Phenylglycine	Structural Classification Animals Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
2-Phenylglycine (DL-α-Phenylglycine) is a metabolite in breast milk during the W2 to W4 lactation period .

HY-N10530

Lactodifucotetraose Difucosyllactose ; 2′,3-Difucosyllactose	Natural Products Polysaccharides Classification of Application Fields Animals Other Diseases Disease Research Fields Saccharides	Others
Lactodifucotetraose (Difucosyllactose) is a tetrasaccharide isolated from human milk. Lactodifucotetraose constitutes of D-glucose, 1 D-galactose, and L-fucose .

HY-W011474

Geranylgeraniol	Structural Classification Natural Products Microorganisms	NF-κB
Geranylgeraniol is an orally acitve vitamin K₂ sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model ^[3] .

HY-N2514

α-Lactose α-D-Lactose	Structural Classification Polysaccharides Animals Classification of Application Fields Source classification Other Diseases Disease Research Fields Saccharides	Others
α-Lactose (α-D-Lactose) is the major sugar present in milk. Lactose exists in the form of two anomers, α and β. The α form normally crystallizes as a monohydrate .

HY-N8873

Silychristin B	Structural Classification Glycine soya Source classification Phenols Polyphenols Plants Compositae	Others
Silychristin B is an antitumor promoter. Silychristin B inhibits TPA induced Epstein-Barr virus early antigen (EBV-EA) induction. Silychristin B can be isolated from milk thistle .

HY-W016979R

δ-Decalactone (Standard)	Structural Classification Natural Products Microorganisms Source classification Rosaceae Plants Amygdalus persica L.	Others
δ-Decalactone (Standard) is the analytical standard of δ-Decalactone. This product is intended for research and analytical applications. δ-Decalactone is a lactone compound found in nonfat dry milks and fruit. δ-Decalactone has a sweet taste .

HY-N1738

2-Methoxystypandrone	Quinones Structural Classification Polygonaceae Reynoutria japonica Houtt. Source classification Plants Naphthalene Quinones	Others
2-Methoxystypandroneis a naphthoquinonethat can be found inPolygonum cuspidatum. 2-Methoxystypandrone showsantioxidantactivities. 2-Methoxystypandrone improves developmental competence of bovine embryos .

HY-P2274

Argifin	Infection Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields	Parasite
Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms, with IC₅₀s of 0.025 μM, 6.4 μM , 1.1 μM and 4.5 μM for SmChiA (Serratia marcescens chitinaese A), SmChiB, Aspergillus fumigatus chitinase B1 and human chitotriosidase, respectively .

HY-P2818

*Alkaline phosphatase, Bovine* intestine** 1 Publications Verification Apase	Structural Classification Natural Products Animals Classification of Application Fields Source classification Metabolic Disease Disease Research Fields	Endogenous Metabolite
Alkaline phosphatase, Bovine intestine (Apase) is a membrane-bound glycoprotein that catalyzes the hydrolysis of phosphate monoesters at alkaline pH. Alkaline phosphatase can be used in molecular biology and enzyme-free analysis. Inhibition of tissue nonspecific alkaline phosphatase can block intracellular lipid accumulation .

HY-N10192

Aculene D	Infection Microorganisms Classification of Application Fields Terpenoids Sesquiterpenes Source classification Disease Research Fields	Endogenous Metabolite Bacterial
Aculene D, a fungal metabolite, shows quorum sensing (QS) inhibitory activity against Chromobacterium violaceum CV026, and could significantly reduce violacein production in N-hexanoyl-l-homoserine lactone (C6-HSL) induced C. violaceum CV026 cultures at sub-inhibitory concentrations .

HY-W011474R

Geranylgeraniol (Standard)	Structural Classification Natural Products Microorganisms	NF-κB
Geranylgeraniol (Standard) is the analytical standard of Geranylgeraniol. This product is intended for research and analytical applications. Geranylgeraniol is an orally acitve vitamin K2 sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model ^[3][4].

HY-N0662

Amentoflavone 5+ Cited Publications Didemethyl-ginkgetin	Structural Classification Flavonoids Classification of Application Fields Source classification Phenols Polyphenols Selaginellaceae Plants Biflavones Selaginella tamariscina (P. Beauv.) Spring Disease Research Fields Cancer	Reactive Oxygen Species Apoptosis Bacterial Fungal RSV GABA Receptor
Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active GABA(A) negative modulator. Amentoflavone also shows anti-inflammatory, antioxidative, anti-viral, anti-tumor, anti-radiation, anti-fungal, antibacterial activity. Amentoflavone induces apoptosis and cell cycle arrest at sub-G1 phase ^[3] .

HY-W087904

α-Lactose hydrate α-D-Lactose hydrate	Structural Classification Polysaccharides Animals Source classification Saccharides	Endogenous Metabolite
α-Lactose (hydrate) (α-D-Lactose (hydrate)) is the principal carbohydrate in the milk of most mammals. α-Lactose (hydrate) consists of glucose and galactose and exists in the form of two anomers, α and β. α-Lactose (hydrate) has many uses in the food and pharmaceutical industries, such as a free-flowing or agglomerating agent, a diluent for pigments, flavors, or enzymes ^[3].

HY-N12323

6′-Galactosyllactose	Structural Classification Polysaccharides Classification of Application Fields Animals Source classification Inflammation/Immunology Disease Research Fields Saccharides	Others
6′-Galactosyllactose is the main oligosaccharide that makes up galactose, a component of human milk. 6′-Galactosyllactose can synthesize human milk oligosaccharides and synthetic galactosyllactose with 3′-Galactosyllactose and 4′-Galactosyllactose, and reduce inflammation in human T84, NCM-460 and H4 cells and intestinal tissues .

HY-N9448

Lacto-N-tetraose	Infection Structural Classification Natural Products Human Gut Microbiota Metabolites Polysaccharides Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields Saccharides	Bacterial
Lacto-N-tetraose is the significant core structure of human milk oligosaccharides (HMOs) naturally existing in human milk. Lacto-N-tetraose is consist of galactose, N-acetylglucosamine, and glucose moieties. Lacto-N-tetraose has prebiotic effect, immune regulatory effect, anti-inflammatory effects, intestinal cell responses regulatory effect, antibacterial activity and antiviral activity. Lacto-N-tetraose has been widely added to infant formula .

HY-125311

Zaragozic acid D	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Farnesyl Transferase
Zaragozic acid D is a squalene synthase inhibitor. Zaragozic acid D also is a farnesyl-protein transferase (FPTase) inhibitor with an IC₅₀ value of 100 nM for bovine FPTase .

HY-N0779A

Silybin 2 Publications Verification Silibinin	Structural Classification Classification of Application Fields Source classification Cyamopsis tetragonoloba (L.) Taub. Plants Compositae Flavanonols Flavonoids Glycine soya Phenols Polyphenols Inflammation/Immunology Disease Research Fields	Apoptosis
Silybin is a flavonolignan isolated from milk thistle (Silybum marianum) seeds. Silybin induces apoptosis and exhibits hepatoprotective, antioxidant, anti-inflammatory, anti-cancer activity .

HY-N10510

Blood group A antigen tetraose type 5 A-Tetrasaccharide	Structural Classification Natural Products Polysaccharides Classification of Application Fields Other Diseases Endogenous metabolite Disease Research Fields Saccharides	Others
Blood group A antigen tetraose type 5 (A-Tetrasaccharide) is a tetrasaccharide and a blood group specific oligosaccharide, inhibits the binding of anti-A antibody to blood group A substance. Blood group A antigen tetraose type 5 can be isolated from polar bear milk samples .

HY-W087904R

α-Lactose (hydrate) (Standard)	Structural Classification Polysaccharides Animals Source classification Saccharides	Endogenous Metabolite
α-Lactose (hydrate) (Standard) is the analytical standard of α-Lactose (hydrate). This product is intended for research and analytical applications. α-Lactose (hydrate) (α-D-Lactose (hydrate)) is the principal carbohydrate in the milk of most mammals. α-Lactose (hydrate) consists of glucose and galactose and exists in the form of two anomers, α and β. α-Lactose (hydrate) has many uses in the food and pharmaceutical industries, such as a free-flowing or agglomerating agent, a diluent for pigments, flavors, or enzymes ^[3].

HY-N10521

6'-Sialyllactose	Structural Classification Polysaccharides Endogenous metabolite Saccharides	Toll-like Receptor (TLR)
6'-Sialyllactose is a sialylated human milk oligosaccharide that can promote the proliferation of bifidobacteria and shaping the gut microbiota. 6'-Sialyllactose also inhibits toll-like receptor 4 signaling and protects against the development of necrotizing enterocolitis .

HY-N8773

3,5,7-Trihydroxychromone	other families Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Phenols Polyphenols Plants Disease Research Fields	Others
3,5,7-Trihydroxychromone is the analogue of galangin. 3,5,7-Trihydroxychromone is also the binder of bovine serum albumin. 3,5,7-Trihydroxychromone undergoes multiple antioxidant pathways .

HY-N0779AR

Silybin (Standard)	Flavanonols Structural Classification Flavonoids Glycine soya Source classification Phenols Polyphenols Cyamopsis tetragonoloba (L.) Taub. Plants Compositae	Apoptosis
Silybin (Standard) is the analytical standard of Silybin. This product is intended for research and analytical applications. Silybin is a flavonolignan isolated from milk thistle (Silybum marianum) seeds. Silybin induces apoptosis and exhibits hepatoprotective, antioxidant, anti-inflammatory, anti-cancer activity .

HY-N0662R

Amentoflavone (Standard)	Structural Classification Flavonoids Source classification Phenols Polyphenols Selaginellaceae Plants Biflavones Selaginella tamariscina (P. Beauv.) Spring	Reactive Oxygen Species Apoptosis Bacterial Fungal RSV GABA Receptor
Amentoflavone (Standard) is the analytical standard of Amentoflavone. This product is intended for research and analytical applications. Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active GABA(A) negative modulator. Amentoflavone also shows anti-inflammatory, antioxidative, anti-viral, anti-tumor, anti-radiation, anti-fungal, antibacterial activity. Amentoflavone induces apoptosis and cell cycle arrest at sub-G1 phase ^[3] .

HY-N9965

2'-Fucosyllactose 2'-FL	Infection Structural Classification Polysaccharides Animals Classification of Application Fields Inflammation/Immunology Disease Research Fields Saccharides	TNF Receptor Interleukin Related
2'-Fucosyllactose (2'-FL) is an oligosaccharide that could be derived from human milk. 2'-Fucosyllactose regulates the expression of CD14, alleviates colitis and regulates the gut microbiome. 2'-Fucosyllactose stimulates T cells to increase IFN-γ production and decreases IL-6, IL-17, and TNF-α production of cytokines .

HY-N7073

Silymarin 5 Publications Verification	Infection Structural Classification Natural Products Glycine soya Neurological Disease Classification of Application Fields Source classification Cyamopsis tetragonoloba (L.) Taub. Plants Compositae Inflammation/Immunology Disease Research Fields	SARS-CoV
Silymarin is an extract of the milk thistle (Silybum marianum). Silymarin is an effective SARS-CoV-2 main protease (M ^pro) inhibitor. Silymarin can significantly reduce tumor cell proliferation, angiogenesis as well as insulin resistance. Silymarin has the chemopreventive effect on hepatocellular carcinoma (HCC). Silymarin has the potential for COVID-19 research .

HY-B0504S

Creatinine-d3 3 Publications Verification NSC13123-d<sub>3sub>	Classification of Application Fields Metabolic Disease Disease Research Fields	Endogenous Metabolite
Creatinine-d₃ is a deuterium labeled Creatinine. Creatinine is a break-down product of creatine phosphate in muscle[1].

HY-W009708

Bis(2-methyl-3-furyl)disulfide	Natural Products Microorganisms Classification of Application Fields Animals Source classification Other Diseases Disease Research Fields	Others
Bis(2-methyl-3-furyl)disulfide, compound (2), is intended to provide a flavoring compound to enhance a natural feeling, a fresh feeling and a milk-rich feeling of a milk-related product .

HY-N15148

Disialyllactose	Structural Classification Polysaccharides Animals Source classification Saccharides	Endogenous Metabolite
Disialyllactose is one of the most abundant milk sialylated oligosaccharides .

HY-N11504

Difucosyllacto-N-neohexaose	Structural Classification Polysaccharides Source classification Endogenous metabolite Saccharides	Others
Difucosyllacto-N-neohexaose is an oligosaccharide that can be isolated from human milk .

HY-B2123

Lactose	Structural Classification Human Gut Microbiota Metabolites Polysaccharides Microorganisms Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields Saccharides	Endogenous Metabolite Bacterial
Lactose, a major sugar in the milk of most species, could regulate human’s intestinal microflora.

HY-N11503

Disialyllacto-N-tetraose	Structural Classification Polysaccharides Source classification Endogenous metabolite Saccharides	Others
Disialyllacto-N-tetraose is a human milk oligosaccharide that prevents necrotising enterocolitis in neonatal rats .

HY-W010178

4-Methyloctanoic acid	Structural Classification Classification of Application Fields Animals Ketones, Aldehydes, Acids Source classification Other Diseases Disease Research Fields	Others
4-Methyloctanoic acid is a natural compound mainly responsible for the characteristic goaty sheepy flavour of sheep and goat milk .

HY-113162

Bovinic acid	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Bovinic acid is a conjugated linoleic acid with anticarcinogenic and anti-atherogenic activities.

HY-W011527

Xanthosine 2 Publications Verification	Natural Products Microorganisms Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Xanthosine is a nucleoside derived from xanthine and ribose. Xanthosine can increase mammary stem cell population and milk production in cattle and goats .

HY-N7575

Lacto-N-fucopentaose II LNFP II	Structural Classification Polysaccharides Classification of Application Fields Source classification Disease markers Metabolic Disease Endogenous metabolite Disease Research Fields Saccharides Cancer	Endogenous Metabolite
Lacto-N-fucopentaose II (LNFP II) is a sialyl-Lewis, hapten of human Lewis bloodgroup determinant. Lacto-N-fucopentaose II monosialo-ganglioside/glycolipid and sialyl derivative, CA 19-9, is a molecular tumour markers (TM) for biliopancreatic malignancy .

HY-B2167

Docosahexaenoic acid Maximum Cited Publications 26 Publications Verification DHA; Cervonic acid	Structural Classification Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Source classification Disease markers Endogenous metabolite Cardiovascular System Disorder	Endogenous Metabolite
Docosahexaenoic Acid (DHA) is an omega-3 fatty acid abundantly present brain and retina. It can be obtained directly from fish oil and maternal milk.

HY-W013803

Xanthosine dihydrate	Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Xanthosine dihydrate is a nucleoside derived from xanthine and ribose. Xanthosine dihydrate can increase mammary stem cell population and milk production in cattle and goats .

Cat. No.	Product Name	Chemical Structure

HY-B2167S

Docosahexaenoic acid-d5
Docosahexaenoic acid-d₅ is the deuterium labeled Docosahexaenoic Acid. Docosahexaenoic Acid (DHA) is an omega-3 fatty acid abundantly present brain and retina. It can be obtained directly from fish oil and maternal milk.

HY-109037S3

Mavacamten-d5
Mavacamten-d₅ (MYK461-d₅; SAR439152-d₅) is deuterium labeled Mavacamten (HY-109037). Mavacamten (MYK461) is an orally active modulator of cardiac myosin, with IC₅₀s of 490, 711 nM for bovine cardiac and human cardiac, respectively.

HY-W010248S

2-Phenylglycine-d5
2-Phenylglycine-d₅ is the deuterium labeled 2-Phenylglycine. 2-Phenylglycine (DL-α-Phenylglycine) is a metabolite in breast milk during the W2 to W4 lactation period[1].

HY-14566S1

Donepezil-d5
Donepezil-d₅ is deuterium labeled Donepezil. Donepezil (E2020 free base) is a specific and potent AChE inhibitor with IC50s of 8.12 nM and 11.6 nM for bovine AChE and human AChE, respectively[1].

HY-114456AS

Ganglioside GM3-d5 Bovine Milk ammonium salt
Ganglioside GM3-d₅ (Bovine Milk ammonium salt) is deuterium labeled Ganglioside GM3 (Bovine Milk ammonium salt).

HY-152002S

Ganglioside GM3-d3 ammonium
Ganglioside GM3-d3 ammonium is a deuterated labeled Ganglioside GM3 ammonium .

HY-114456S

Ganglioside GM3-d7

Ganglioside GM3-d₇ is deuterium labeled Ganglioside GM3. Ganglioside GM3 is a precursor of a-, b-, and c-series gangliosides, interacts with transmembrane receptors such as the epidermal growth factor and insulin receptors, and regulates receptor functions by creating a specialized lipid environment. Ganglioside GM3 is synthesized by GM3 synthase and can be used for the research of hypercholesterolemia ^[3].

HY-10844S1

Pretomanid-d5
Pretomanid-d₅ is deuterated labeled Pretomanid (HY-10844). Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 μg/mL.

HY-B1374S1

Florfenicol-d3
Florfenicol-d₃ is the deuterium labeled Florfenicol. Florfenicol, a commonly used veterinary antibiotic, is currently indicated for bovine respiratory disease, and also used in aquaculture for the control of enteric septicemia in catfish. Florfenicol can induce early embryonic death in eggs, with an LC50 of 1.07 μg/g.

HY-146876S

*C18:0 GM1 Ganglioside-d5 ammonium*
C18:0 GM1 Ganglioside-d₅ (ammonium) is deuterium labeled C18:0 GM1 Ganglioside (ammonium).

HY-166325A

Ganglioside GD3-d3 ammonium
Ganglioside GD3-d3 (ammonium) is an ester product.

HY-W012481S

Nirvanol-d5
Nirvanol-d₅ is deuterium labeled Nirvanol.

HY-B0184S1

Felbamate-d5
Felbamate-d₅ is the deuterium labeled Felbamate[1]. Felbamate (W-554) is a potent nonsedative anticonvulsant whose clinical effect may be related to the inhibition of N-methyl-D-aspartate (NMDA)[2][3].

HY-U00315S

Gidazepam-d5
Gidazepam-d5 is a deuterium labeled Gidazepam. Gidazepam is an agonist of GABA receptor channels (GABA RCs), and has anticonvulsant effect .

HY-16560S

Camptothecin-d5

Camptothecin-d₅ is the deuterium labeled Camptothecin. Camptothecin (CPT), a kind of alkaloid, is a DNA topoisomerase I (Topo I) inhibitor with an IC50 of 679 nM[1]. Camptothecin (CPT) exhibits powerful antineoplastic activity against colorectal, breast, lung and ovarian cancers, modulates hypoxia-inducible factor-1α (HIF-1α) activity by changing microRNAs (miRNA) expression patterns in human cancer cells[2][3].

HY-B0715S2

Pentoxifylline-d5

Pentoxifylline-d₅ is the deuterium labeled Pentoxifylline. Pentoxifylline (BL-191), a haemorheological agent, is an orally active non-selective phosphodiesterase (PDE) inhibitor, with immune modulation, anti-inflammatory, hemorheological, anti-fibrinolytic and anti-proliferation effects. Pentoxifylline can be used for the research of peripheral vascular disease, cerebrovascular disease and a number of other conditions involving a defective regional microcirculation[1][2][3].

HY-107819S

5α-Cholestan-3β-ol-d5
5α-Cholestan-3β-ol-d₅ is the deuterium labeled 5α-Cholestan-3β-ol. 5α-Cholestan-3β-ol is a derivitized steroid compound[1].

HY-N0573S

Umbelliferone-d5
Umbelliferone-d₅ is the deuterium labeled Umbelliferone. Umbelliferone (7-Hydroxycoumarin), a natural product of the coumarin family, is a fluorescing compound which can be used as a sunscreen agent.

HY-W022036S

2-Ethoxyphenol-d5
2-Ethoxyphenol-d₅ is the deuterium labeled 2-Ethoxyphenol[1].

HY-66005S5

Acetaminophen-d5
Acetaminophen-d₅ is deuterated-labeled Acetaminophen.

HY-16562AS

Irinotecan-d5 hydrochloride
Irinotecan-d₅ hydrochloride is deuterated labeled Irinotecan hydrochloride (HY-16562A). Irinotecan hydrochloride ((+)-Irinotecan hydrochloride) is a topoisomerase I inhibitor mainly used to treat colon cancer and rectal cancer .

HY-B0828S

Triazophos-d5
Triazophos-d5 is the deuterium labeled Triazophos(HY-B0828) .

HY-144162S

(Rac)-Selegiline-d5 hydrochloride
(Rac)-Selegiline-d₅ (hydrochloride) is the deuterium labeled (Rac)-Selegiline hydrochloride[1].

HY-13777S

Zoledronic acid-d5
Zoledronic acid-d₅ is deuterated labeled Zoledronic Acid (HY-13777). Zoledronic Acid (Zoledronate) is a third-generation bisphosphonate (BP), with potent anti-resorptive activity. Zoledronic Acid inhibits the differentiation and apoptosis of osteoclasts. Zoledronic Acid also has anti-cancer effects .

HY-B1207S

Urethane-d5
Urethane-d₅ is the deuterium labeled Urethane. Urethane (Ethyl carbamate), the ethyl ester of carbamic acid, is a byproduct of fermentation found in various food products. Urethane has the ability to suppress bacterial, protozoal, sea urchin egg, and plant tissue growth in vitro[1].

HY-77839S

Cortodoxone-d5
Cortodoxone-d₅ is the deuterium labeled Cortodoxone.

HY-14814S

Delafloxacin-d5
Delafloxacin-d₅ is deuterium labeled Delafloxacin. Delafloxacin (RX-3341; WQ-3034; ABT492) is a broad-spectrum fluoroquinolone antibiotic. Delafloxacin has a broad spectrum of activity that includes drug-resistant Staphylococcus aureus, Streptococcus pneumoniae, and Klebsiella pneumonia[1].

HY-13636S1

Fulvestrant-d5
Fulvestrant-d5 is a isotope of Fulvestrant .

HY-B0200S

Cephalexin-d5
Cephalexin-d₅ is deuterium labeled Cephalexin. Cephalexin (Cefalexin; Cephacillin) is a potent, orally active and the first-generation cephalosporin antibiotic. Cephalexin kills gram-positive and some gram-negative bacteria by disrupting the growth of the bacterial cell wall. Cephalexin monohydrate is used for the research of pneumonia, strep throat, and bacterial endocarditis, et al[1].

HY-B0178AS1

Guanidine-d5 hydrochloride
Guanidine-d₅ (hydrochloride) is the deuterium labeled Guanidine hydrochloride[1]. Guanidine hydrochloride (Guanidinium chloride) a strong chaotrope, is also a strong denaturant of proteins[2][3].

HY-N0570S1

Hydroxytyrosol-d5
Hydroxytyrosol-d₅ is the deuterium labeled Hydroxytyrosol. Hydroxytyrosol (DOPET) is a phenolic compound drawn from the olive tree and its leaves with anti-oxidant, anti-atherogenic, anti-thrombotic, antimicrobial, anti-inflammatory and anti-tumour effects[1][2].

HY-B0941S

6-Benzylaminopurine-d5
6-Benzylaminopurine-d₅ is the deuterium labeled 6-Benzylaminopurine. 6-Benzylaminopurine is a cytokinin[1].

HY-B0878S

Halobetasol propionate-d5
Halobetasol propionate-d₅ is deuterium labeled Halobetasol (propionate).

HY-12760S

Indoramin-d5
Indoramin-d₅ is deuterium labeled Indoramin, which is a piperidine antiadrenergic agent.

HY-14648S

Dexamethasone-d5

Dexamethasone-d₅ is the deuterium labeled Dexamethasone. Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist. Dexamethasone also significantly decreases CD11b, CD18, and CD62L expression on neutrophils, and CD11b and CD18 expression on monocytes. Dexamethasone is highly effective in the control of COVID-19 infection. Dexamethasone inhibits production of exosomes containing inflammatory microRNA-155 in lipopolysaccharide-induced macrophage inflammatory responses[1][2].

HY-B0422S

Nateglinide-d5
Nateglinide-d₅ is a deuterium labeled Nateglinide. Nateglinide, a D-phenylalanine derivative, is an orally active and short-acting insulinotropic agent and a DPP IV inhibitor. Nateglinide inhibits ATP-sensitive K+ channels in pancreatic β-cells. Nateglinide is used for the treatment of type 2 (non-insulin-dependent) diabetes mellitus[1][2].

HY-17043S1

Loratadine-d5
Loratadine-d₅ is the deuterium labeled Loratadine. Loratadine (SCH-29851) is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM. Loratadine has anti-dengue-virus (DENV) activity. Loratadine can inhibit immunologic release of inflammatory mediators.

HY-141642S

Triheptadecanoin-d5
Triheptadecanoin-d₅ is the deuterium labeled Triheptadecanoin[1].

HY-B0521S

Altrenogest-d5
Altrenogest-d₅ is the deuterium labeled Altrenogest. Altrenogest (Allyltrenbolone) is a progestogen structurally related to veterinary steroid trenbolone.

HY-109592S

Imidaprilate-d5
Imidaprilate-d₅ is deuterium labeled Imidaprilate. Imidaprilate is an active metabolite of TA-6366, acts as a potent angiotensin converting enzyme (ACE) inhibitor, with an IC50 of 2.6 nM, and is used in the research of hypertensive disease.

HY-B0808S1

Oxaprozin-d5
Oxaprozin-d₅ is deuterium labeled Oxaprozin. Oxaprozin is an inhibitor of both COX-1 and COX-2 with IC50s of 2.2 μM and 36 μM for human platelet COX-1 and IL-1-stimulated human synovial cell COX-2, respectively. Oxaprozin also inhibits the activation of NF-κB.

HY-12199BS

Pitolisant-d5 hydrochloride
Pitolisant-d5 hydrochloride (Ciproxidine-d5 hydrochloride) is the deuterium labeled Pitolisant hydrochloride (HY-12199B). Pitolisant hydrochloride is a potent and selective nonimidazole inverse agonist at the recombinant human histamine H3 receptor (K_i=0.16 nM) .

HY-B0346S

Propylthiouracil-d5
Propylthiouracil-d₅ is the deuterium labeled Propylthiouracil. Propylthiouracil (6-Propyl-2-thiouracil) is a thyroperoxidase and 5'-deiodinase inhibitor.

HY-12222S

Obeticholic acid-d5
Obeticholic acid-d₅ is the deuterium labeled Obeticholic acid. Obeticholic acid (INT-747) is a potent, selective and orally active FXR agonist with an EC50 of 99 nM. Obeticholic acid has anticholeretic and anti-inflammation effect. Obeticholic acid also induces autophagy[1][2][3].

HY-B0141S2

Estradiol-d5
Estradiol-d₅ is deuterium labeled Estradiol. Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway[1][2][3].

HY-14649S4

Retinoic acid-d5

Retinoic acid-d₅ is the the deuterium labeled Retinoic acid (HY-14649). Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC₅₀s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with K_d of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha ^[3] ^[5].

HY-17357S

Nepafenac-d5
Nepafenac-d₅ is the deuterium labeled Nepafenac, which is a selective COX-2 inhibitor.

HY-B0660S

Eicosapentaenoic Acid-d5
Eicosapentaenoic Acid-d₅ is the deuterium labeled Eicosapentaenoic Acid. Eicosapentaenoic Acid (EPA; Timnodonic acid) is an omega-3 fatty acid.

HY-10162S

Olaparib-d5
Olaparib-d₅ is a deuterium labeled Olaparib. Olaparib is a potent and oral PARP inhibitor[1].

HY-13026S

Idelalisib-d5
Idelalisib-d₅ is a deuterium labeled Idelalisib. Idelalisib is a highly selective and orally bioavailable p110δ inhibitor[1].

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks