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4'-Hydroxy pyrimethanil-d<sub>4</sub>

" in MedChemExpress (MCE) Product Catalog:

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Click Chemistry:	DBCO (1) PROTAC Synthesis (1) Azide (2) Alkynes (18)
Oligonucleotides:	Nucleosides and their Analogs (12) Flavoring Agents (1) Pre-designed siRNA Sets (1) Phospholipids (11) Cationic Lipids (1) Polymers (3) Antisense Oligonucleotides (1) siRNAs (10)

3957

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3057

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Oligonucleotides

Targets Recommended: P-glycoprotein

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B2033S1

Pyrimethanil-d5	Fungal Isotope-Labeled Compounds	Others
Pyrimethanil-d₅ is the deuterium labeled Hypoxanthine. Hypoxanthine, a purine derivative, is a potential free radical generator and could be used as an indicator of hypoxia.

HY-W742358

*4'-Hydroxy* pyrimethanil-d4**	Isotope-Labeled Compounds	Others
4'-Hydroxy pyrimethanil-d₄ is the deuterium labeled 4'-Hydroxy pyrimethanil. Radioactive isotopes labeled compounds can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified .

HY-RS13999

SUB1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SUB1 Human Pre-designed siRNA Set A contains three designed siRNAs for SUB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SUB1 Human Pre-designed siRNA Set A SUB1 Human Pre-designed siRNA Set A

HY-146227

DNA topoisomerase II inhibitor 1	Topoisomerase Apoptosis	Cancer
DNA topoisomerase II inhibitor 1 (compound 8ed) is a potent DNA topoisomerase II inhibitor. DNA topoisomerase II inhibitor 1 shows anti-proliferative activity. DNA topoisomerase II inhibitor 1 induces apoptosis and cell cycle arrest at sub G1 phase .

HY-121385S1

Hydroxy Bosentan-d4 Ro 48-5033-d<sub>4sub>	Isotope-Labeled Compounds Endogenous Metabolite	Cardiovascular Disease
Hydroxy Bosentan-d₄ is deuterium labeled Hydroxy bosentan. Hydroxy bosentan (Ro 48-5033) is a primary metabolite of Bosentan (BOS) metabolized by the cytochrome P450 system in the liver. Ro 48-5033 assists BOS pharmacologically, retaining 10%-20% activities[1].

HY-115354S

*4-Hydroxy* Alprazolam-d5** 4-Hydroxyalprazolam-d<sub>5sub>; RS-4-Hydroxyalprazolam-d<sub>5sub>	Isotope-Labeled Compounds	Others
4-Hydroxy Alprazolam-d5 (4-Hydroxyalprazolam-d5; RS-4-Hydroxyalprazolam-d5) is the deuterium labeled 4-hydroxy Alprazolam (HY-115354) .

HY-W012927S

*4-Hydroxy-5-methylfuran-3(2H)-one-d3* Chicory furaneol-d<sub>3sub>	Isotope-Labeled Compounds	Others
4-Hydroxy-5-methylfuran-3(2H)-one-d₃ is deuterated labeled 2-Isopropyl-3-methoxypyrazine.

HY-126121S

*2-Hydroxy* Ibuprofen-d6** (±)-2-Hydroxy Ibuprofen-d<sub>6sub>	Isotope-Labeled Compounds COX	Inflammation/Immunology Cancer
2-Hydroxy Ibuprofen-d₆ is the deuterium labeled 2-Hydroxy Ibuprofen. 2-Hydroxy Ibuprofen is a metabolite of Ibuprofen. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively[1][2].

HY-G0003S1

*Iloperidone metabolite Hydroxy* Iloperidone-d3** P88-d<sub>3sub>; Hydroxy Iloperidone-d<sub>3sub>	Drug Metabolite	Others
Iloperidone metabolite Hydroxy Iloperidone-d₃ is the deuterium labeled Iloperidone metabolite Hydroxy Iloperidone[1].

HY-12773AS2

*5-Hydroxy* Propafenone-d6 hydrochloride** GPV-129-d<sub>6sub> hydrochloride	Isotope-Labeled Compounds	Others
5-Hydroxy Propafenone-d₆ hydrochloride is deuterated labeled 5-Hydroxy Propafenone.

HY-10844S1

Pretomanid-d5 PA-824-d<sub>5sub>; (S)-PA 824-d<sub>5sub>	Antibiotic Bacterial Isotope-Labeled Compounds	Infection Cancer
Pretomanid-d₅ is deuterated labeled Pretomanid (HY-10844). Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 μg/mL.

HY-12772S

Hydroxy Itraconazole-d8 R-63373-d<sub>8sub>	Fungal	Others
Hydroxy Itraconazole-d₈ is the deuterium labeled Hydroxy Itraconazole. Hydroxy Itraconazole is an active metabolite of Itraconazole (ITZ), which is a triazole antifungal agent.

HY-W010305S

*5-Ethyl-3-hydroxy-4-methylfuran-2(5H)-one-d4* Ethyl Fenugreek Lactone-d<sub>4sub>	Isotope-Labeled Compounds	Others
5-Ethyl-3-hydroxy-4-methylfuran-2(5H)-one-d₄ is deuterated labeled 6-Heptyltetrahydro-2H-pyran-2-one.

HY-131543S

*22-Hydroxy* Mifepristone-d6** RU 42698-d<sub>6sub>	Isotope-Labeled Compounds	Others
22-Hydroxy Mifepristone-d₆ is the deuterium labeled 22-Hydroxy Mifepristone[1]. 22-Hydroxy Mifepristone-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W025101S

*Ethyl 3-hydroxy-3-methylbutanoate-d6* Ethyl 3-Hydroxy-3-methylbutyrate-d<sub>6sub>	Isotope-Labeled Compounds	Others
Ethyl 3-hydroxy-3-methylbutanoate-d₆ is the deuterium labeled Ethyl 3-hydroxy-3-methylbutanoate[1].

HY-111975S1

*7'-Hydroxy* ABA-d2** 7'-OH ABA-d<sub>2sub>	Isotope-Labeled Compounds	Others
7'-Hydroxy ABA-d₂2 is the deuterium labeled 7'-Hydroxy ABA[1].

HY-111975S5

*7'-Hydroxy* ABA-d7** 7'-OH ABA-d<sub>7sub>	Isotope-Labeled Compounds	Others
7'-Hydroxy ABA-d₇ is the deuterium labeled 7'-Hydroxy ABA[1].

HY-151930S

*8′-Hydroxy* ABA-d8** 8'-OH-ABA-d<sub>8sub>	Drug Metabolite	Others
8′-Hydroxy ABA-d₈ is the deuterium labeled 8’-Hydroxy ABA[1].

HY-151930S1

*8′-Hydroxy* ABA-d2** 8'-OH-ABA-d<sub>2sub>	Drug Metabolite	Others
8′-Hydroxy ABA-d₂ is the deuterium labeled 8’-Hydroxy ABA[1].

HY-108263S

*3-Hydroxy* Midostaurin-d5** CGP52421-d<sub>5sub>	Isotope-Labeled Compounds FLT3	Cancer
3-Hydroxy Midostaurin-d₅ is a deuterium labeled 3-Hydroxy Midostaurin. 3-Hydroxy Midostaurin is a metabolite of PKC412, which effectively inhibits FMS-like tyrosine kinase-3 (FLT3) autophosphorylation with IC50s of approximately 132 nM and 9.8 μM in culture medium and plasma, respectively[1].

HY-W008216S

HMMNI-d3 Hydroxy Dimetridazole-d<sub>3sub>	Drug Metabolite Isotope-Labeled Compounds	Infection
HMMNI-d₃ is deuterium labeled HMMNI. HMMNI (Hydroxy dimetridazole) is a hydroxy metabolite of Dimetridazole. Dimetridazole is a nitroimidazole class agent that combats protozoan infections[1].

HY-B0151S

Pregnenolone-d4 3β-Hydroxy-5-pregnen-20-one-d<sub>4sub>	Cannabinoid Receptor TRP Channel Endogenous Metabolite Autophagy	Neurological Disease
Pregnenolone-d₄ is the deuterium labeled Pregnenolone. Pregnenolone (3β-Hydroxy-5-pregnen-20-one) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone can protect the brain from cannabis intoxication[1][2]. Pregnenolone is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels[3].

HY-121385S

Hydroxy Bosentan-d6 Ro 48-5033-d<sub>6sub>	Isotope-Labeled Compounds Endogenous Metabolite	Cardiovascular Disease
Hydroxy Bosentan-d₆ is deuterium labeled Hydroxy bosentan. Hydroxy bosentan (Ro 48-5033) is a primary metabolite of Bosentan (BOS) metabolized by the cytochrome P450 system in the liver. Ro 48-5033 assists BOS pharmacologically, retaining 10%-20% activities[1].

HY-113038AS1

α-Hydroxyglutaric acid-d4 disodium 2-Hydroxyglutarate-d<sub>4sub> disodium; 2-Hydroxyglutaric acid-d<sub>4sub> disodium; 2-Hydroxypentanedioic acid-d<sub>4sub> disodium	Histone Demethylase Endogenous Metabolite	Cancer
α-Hydroxyglutaric acid-d₄ (disodium) is the deuterium labeled α-Hydroxyglutaric acid disodium[1]. α-Hydroxyglutaric acid (2-Hydroxyglutarate) disodium is an α-hydroxy acid form of glutaric acid. α-Hydroxyglutaric acid disodium is a competitive inhibitor of multiple α-ketoglutarate-dependent dioxygenases, including histone demethylases and the TET family of 5-methlycytosine (5mC) hydroxylases[2].

HY-W354610S

*N-(4-Hydroxy-3-methoxybenzyl)stearamide-d3* N-Vanillyloctadecanamide-d<sub>3sub>	Isotope-Labeled Compounds	Others
N-(4-Hydroxy-3-methoxybenzyl)stearamide-d₃ is the deuterium labeled N-(4-hydroxy-3-methoxybenzyl)stearamide[1].

HY-41680S

4-Aminobenzonitrile-d4 4-Aminobenzonitrile-d<sub>4sub>; 4-Cyanoaniline-d<sub>4sub>; 4-Cyanobenzenamine-d<sub>4sub>	Isotope-Labeled Compounds	Others
4-Aminobenzonitrile-d₄ is the deuterium labeled 4-Aminobenzonitrile[1].

HY-66005S

Acetaminophen-d4 Paracetamol-d<sub>4sub>; 4-Acetamidophenol-d<sub>4sub>; 4'-Hydroxyacetanilide-d<sub>4sub>	COX Histone Acetyltransferase Endogenous Metabolite	Inflammation/Immunology
Acetaminophen-d₄ is the deuterium labeled Acetaminophen. Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM; is a widely used antipyretic and analgesic agent[1][2][3]. Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor[4].

HY-12773AS

*5-Hydroxy* Propafenone-d5 hydrochloride** GPV-129 D5 Hydrochloride; Lu 40-545 d<sub>5sub>	Isotope-Labeled Compounds	Cardiovascular Disease
5-Hydroxy Propafenone-d₅ (hydrochloride) is the deuterium labeled 5-Hydroxy Propafenone.

HY-B1159S

Nitroxoline-D4 8-Hydroxy-5-nitroquinoline-d<sub>4sub>; 5-Nitro-8-quinolinol-d<sub>4sub>	Bacterial Autophagy Antibiotic	Infection Cancer
Nitroxoline-d₄ is the deuterium labeled Nitroxoline. Nitroxoline is an antibiotic that has proven to be very effective at combating biofilm infections. Nitroxoline functions by chelating Fe2+ and Zn2+ ions from the biofilm matrix[1][2].

HY-B0151S2

Pregnenolone-d4-1 3β-Hydroxy-5-pregnen-20-one-d<sub>4sub>-1	Cannabinoid Receptor TRP Channel Endogenous Metabolite Autophagy	Neurological Disease
Pregnenolone-d₄-1 is the deuterium labeled Pregnenolone. Pregnenolone (3β-Hydroxy-5-pregnen-20-one) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone can protect the brain from cannabis intoxication[1][2]. Pregnenolone is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels[3].

HY-118714S

*α-Hydroxy* alprazolam-d5** U 40125-d<sub>5sub>; alpha-Hydroxyalprazolam-d<sub>5sub>	Isotope-Labeled Compounds	Others
α-Hydroxy alprazolam-d₅ (U 40125-d₅; alpha-Hydroxyalprazolam-d₅) is the deuterium labled α-hydroxy alprazolam (HY-118714).

HY-110189S1

Pregnenolone monosulfate-d4 sodium 3β-Hydroxy-5-pregnen-20-one monosulfate-d<sub>4sub> sodium	Isotope-Labeled Compounds Cannabinoid Receptor TRP Channel Endogenous Metabolite Autophagy	Neurological Disease
Pregnenolone monosulfate-d₄ (sodium) is the deuterium labeled Pregnenolone monosulfate. Pregnenolone monosulfate sodium (3β-Hydroxy-5-pregnen-20-one monosulfate sodium) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone monosulfate sodium acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone monosulfate sodium can protect the brain from cannabis intoxication[1][2]. Pregnenolone monosulfate sodium is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels[3].

HY-Y1042S

4-Cyanophenol-d4 4-Hydroxybenzonitrile-d<sub>4sub>; 4-Hydroxycyanobenzene-d<sub>4sub>; NSC 400524-d<sub>4sub>	Isotope-Labeled Compounds	Others
4-Cyanophenol-d₄ is the deuterium labeled 4-Cyanophenol[1].

HY-17461S3

Cortisone-d2 17-Hydroxy-11-dehydrocorticosterone-d<sub>2sub>; Kendall's compound E-d<sub>2sub>	Isotope-Labeled Compounds Glucocorticoid Receptor Endogenous Metabolite	Endocrinology
Cortisone-d₂ is the deuterium labeled Cortisone. Cortisone (17-Hydroxy-11-dehydrocorticosterone), an oxidized metabolite of Cortisol (a Glucocorticoid). Cortisone acts as an immunosuppressant and anti-inflammatory agent. Cortisone can partially intervene in binding of Glucocorticoid to Glucocorticoid-receptor at high concentrations[1][3][4][5].

HY-100634SA

4-Hydroxypropranolol-d7 (±)-4-Hydroxy Propranolol-d<sub>7sub>	Isotope-Labeled Compounds Adrenergic Receptor	Neurological Disease
4-Hydroxypropranolol-d₇ is the deuterium labeled 4-Hydroxypropranolol hydrochloride. 4-Hydroxypropranolol hydrochlorid is an active metabolite of Propranolol. 4-Hydroxypropranolol hydrochlorid is of comparable potency to Propranolol. 4-Hydroxypropranolol hydrochlorid inhibits β1- and β2-adrenergic receptors with pA2 values of 8.24 and 8.26, respectively. 4-Hydroxypropranolol hydrochlorid has intrinsic sympathomimetic activity, membrane stabilizing activity and potent antioxidant properties[1][2][3].

HY-17413S2

Zidovudine-d4 Azidothymidine-d<sub>4sub>; AZT-d<sub>4sub>; ZDV-d<sub>4sub>	CRISPR/Cas9 HIV Isotope-Labeled Compounds	Infection Cancer
Zidovudine-d₄ is deuterated labeled Zidovudine (HY-17413). Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection. Zidovudine increases CRISPR/Cas9-mediated editing frequency.

HY-32351AS

Calcifediol-d6 monohydrate 25-Hydroxy Vitamin D3-d<sub>6sub> monohydrate	Isotope-Labeled Compounds VD/VDR Endogenous Metabolite	Metabolic Disease
Calcifediol-d₆ monohydrate is the deuterium labeled Calcifediol monohydrate. Calcifediol monohydrate (25-hydroxy Vitamin D3 monohydrate), is an effective VDR ligand and VD supplement. Calcifediol is a prohormone of the vitamin D endocrine system (VDES) and is hydroxylated in the liver to produce the active form, calcitriol. Calcifediol can rapidly increase serum VD levels .

HY-B1008S

4-Aminobenzoic acid-d4 PABA-d<sub>4sub>; Vitamin Bx-d<sub>4sub>; Vitamin H1-d<sub>4sub>; p-Aminobenzoic acid-d<sub>4sub>	Isotope-Labeled Compounds Endogenous Metabolite	Others
4-Aminobenzoic acid-d₄ is the deuterium labeled 4-Aminobenzoic acid. 4-Aminobenzoic acid is an intermediate in the synthesis of folate by bacteria, plants, and fungi.

HY-N0006S1

Demethoxycurcumin-d4 Curcumin II-d<sub>4sub>; Desmethoxycurcumin-d<sub>4sub>; Monodemethoxycurcumin-d<sub>4sub>	Apoptosis Autophagy Bacterial	Cancer
Demethoxycurcumin-d₄ is the deuterium labeled Demethoxycurcumin. Demethoxycurcumin (Curcumin II) is a major active curcuminoid; possess anti-inflammatory properties[1].

HY-B0329S

Isoniazid-d4 INH-d<sub>4sub>; Isonicotinic acid hydrazide-d<sub>4sub>; Isonicotinic hydrazide-d<sub>4sub>	Bacterial Autophagy Mitophagy Antibiotic	Infection
Isoniazid-d₄ is the deuterium labeled Isoniazid. Isoniazid (INH) is a proagent and must be activated by a bacterial catalase-peroxidase enzyme KatG. Isoniazid is bactericidal to rapidly dividing mycobacteria and has anti-tuberculostatic activity[1][2][3][4].

HY-100048S

Acetylisoniazid-d4 Acetylisoniazide-d<sub>4sub>; N-Monoacetylisoniazid-d<sub>4sub>; NSC 36084-d<sub>4sub>	Isotope-Labeled Compounds	Others
Acetylisoniazid-d₄ is the deuterium labeled Acetylisoniazid[1].

HY-118861S

Enclomiphene-d4 hydrochloride (E)-Clomiphene-d<sub>4sub> hydrochloride; trans-Clomiphene-d<sub>4sub> hydrochloride; Enclomifene-d<sub>4sub> hydrochloride	Isotope-Labeled Compounds Estrogen Receptor/ERR	Inflammation/Immunology
Enclomiphene-d₄ (hydrochloride) is a deuterium labeled Enclomiphene. Enclomiphene-d₄ (hydrochloride) is a potent and orally active oestrogen receptor antagonist, with antioestrogenic property[1].

HY-109015S

Tucidinostat-d4 Chidamide-d<sub>4sub>; HBI-8000-d<sub>4sub>; CS 055-d<sub>4sub>	Isotope-Labeled Compounds HDAC	Cancer
Tucidinostat-d₄ is the deuterium labeled Tucidinostat. Tucidinostat is a potent and orally bioavailable HDAC enzymes class I (HDAC1/2/3) and class IIb (HDAC10) inhibitor, with IC50s of 95, 160, 67 and 78 nM, respectively[1].

HY-19696AS

Tauroursodeoxycholate-d4 sodium Tauroursodeoxycholic acid-d<sub>4sub> sodium; TUDCA-d<sub>4sub> sodium; UR 906-d<sub>4sub> sodium	Isotope-Labeled Compounds ERK Caspase Apoptosis Endogenous Metabolite	Cancer
Tauroursodeoxycholate-d₄ (sodium) is the deuterium labeled Tauroursodeoxycholate sodium. Tauroursodeoxycholate (Tauroursodeoxycholic acid; TUDCA) sodium is an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12. Tauroursodeoxycholate also inhibits ERK.

HY-19696S1

Tauroursodeoxycholate-d4 Tauroursodeoxycholic acid-d<sub>4sub>; TUDCA-d<sub>4sub>; UR 906-d<sub>4sub>	Isotope-Labeled Compounds ERK Caspase Endogenous Metabolite Apoptosis	Cancer
Tauroursodeoxycholate-d₄ is deuterium labeled Tauroursodeoxycholate. Tauroursodeoxycholate (Tauroursodeoxycholic acid) is an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12. Tauroursodeoxycholate also inhibits ERK.

HY-B0389S24

D-Glucose-d4 Glucose-d<sub>4sub>; D-(+)-Glucose-d<sub>4sub>; Dextrose-d<sub>4sub>	Endogenous Metabolite	Metabolic Disease Cancer
D-Glucose-d₄ is the deuterium labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molec

HY-B0696AS

Tiagabine-d4 hydrochloride NO050328-dd<sub>4sub> hydrochloride; NO328-d<sub>4sub> hydrochloride; TGB-d<sub>4sub> hydrochloride	GABA Receptor Isotope-Labeled Compounds	Neurological Disease
Tiagabine-d₄ hydrochloride is deuterated labeled Tiagabine hydrochloride (HY-B0696A). Tiagabine hydrochloride is a potent and selective GABA reuptake inhibitor, used as an anticonvulsant agent, with IC₅₀s of 67, 446 and 182 nM for [ ³H]GABA uptake in Synaptosomes, Neurons and Glia, respectively .

HY-13273S

Ostarine-d4 MK-2866-d<sub>4sub>; GTX-024-d<sub>4sub>; Enobosarm-d<sub>4sub>	Isotope-Labeled Compounds Androgen Receptor	Cancer
Ostarine-d4 is a deuterated labeled Ostarine .

HY-34498S

4-Chloro-2-methylphenol-d4 4-Chloro-o-cresol-d<sub>4sub>; 4-Chlorocresol-d<sub>4sub>; 5-Chloro-2-Hydroxytoluene-d<sub>4sub>	Isotope-Labeled Compounds	Others
4-Chloro-2-methylphenol-d₄ is the deuterium labeled 4-Chloro-2-methylphenol[1].

HY-107542S

Oleoylethanolamide-d4 N-Oleoylethanolamide-d<sub>4sub>; Oleamide MEA-d<sub>4sub>; Oleic acid monoethanolamide-d<sub>4sub>	Isotope-Labeled Compounds Endogenous Metabolite PPAR	Cardiovascular Disease Metabolic Disease
Oleoylethanolamide-d₄ is the deuterium labeled Oleoylethanolamide. Oleoylethanolamide is a high affinity endogenous PPAR-α agonist, which plays an important role in the treatment of obesity and arteriosclerosis.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-125833

Alpha-Naphthoflavone 5+ Cited Publications	Flavonoids Flavones Source classification Indigofera heterantha Wall. ex Brand. Plants Compositae Disease Research Fields Cancer	Cytochrome P450 Aryl Hydrocarbon Receptor Apoptosis
Alpha-Naphthoflavone is an orally active flavonoid that is a potent, competitive inhibitor of aromatase< b>aromatase. < b > IC < sub > 50 < / sub > < / b > and < b > K < sub > I < / sub > < / b > value were 0.5 and 0.2 microns. Alpha-Naphthoflavone can inhibit cell proliferation and induce apoptosis ^[4].

HY-W751835

Baloxavir-d4 Maximum Cited Publications 30 Publications Verification Baloxavir acid-d<sub>4sub>; S-033447-d<sub>4sub>	Classification of Application Fields Disease Research Fields Cancer	Isotope-Labeled Compounds
Baloxavir-d₄ (Baloxavir acid-d₄; S-033447-d₄) is the deuterium-labeled Baloxavir (HY-109025A). Baloxavir-d₄ (Baloxavir-d₄ acid), derived from the proagent Baloxavir-d₄ marboxil, is a first-in-class, potent and selective cap-dependent endonuclease (CEN) inhibitor within the polymerase PA subunit of influenza A and B viruses. Baloxavir-d₄ inhibits viral RNA transcription and replication and has potently antiviral activity .

HY-W011474

Geranylgeraniol	Structural Classification Natural Products Microorganisms	NF-κB
Geranylgeraniol is an orally acitve vitamin K₂ sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model ^[4].

HY-N9241

*3-Hydroxy-7-methoxyflavone*	Structural Classification Flavonols Flavonoids Labiatae Source classification Gymnaster koraiensis Plants	Others
3-Hydroxy-7-methoxyflavone (compound 1) is a flavonoid. 3-Hydroxy-7-methoxyflavone is isolated from natural Salvia elegans. 3-Hydroxy-7-methoxyflavone has anti-anxiety effect .

HY-N11799

Neochilenin 3-O-Methylquercetin 4′-O-glucoside	Structural Classification Flavonoids Source classification Plants Compositae Other Flavonoids	Others
Neochilenin (3-O-Methylquercetin 4 '-O-glucoside) is a glycoside of 3-O-methylquercetin, which can be isolated from the sub-family Cereoideae (Cactaceae). .

HY-N9012

*2-Hydroxy-5-(2-hydroxy-4-methoxybenzyl)-4-methoxybenzaldehyde*	Structural Classification Source classification Phenols Dalbergia congesta Graham ex Wight & Arn. Plants Fabaceae	Others
2-Hydroxy-5-(2-hydroxy-4-methoxybenzyl)-4-methoxybenzaldehyde is a Phenols product that can be isolated from the roots of Dalbergia congesta .

HY-N9224

*5-Acetyl-6-hydroxy-2-(1-hydroxy-1-methylethyl)benzofuran*	Structural Classification Monophenols Source classification Artemisia dracunculus L. Phenols Plants Compositae	Others
5-Acetyl-6-hydroxy-2-(1-hydroxy-1-methylethyl)benzofuran is a Phenols product that can be isolated from the herbs of Artemisia dracunculus. .

HY-116688

*2-Hydroxy-4-(methylthio)butyric acid*	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Others
2-Hydroxy-4-(methylthio)butyric acid is a dietary essential amino acid which is converted to Methionine (HY-13694) by 2-hydroxy acid dehydrogenase and 2-hydroxy acid oxidase. 2-Hydroxy-4-(methylthio)butyric acid is promising for research of gut disease .

HY-N2674

*5-Hydroxy-1-methoxyxanthone* 5-Hydroxy-1-methoxyxanthen-9-one	Structural Classification Flavonoids Hypericum brasiliense Choisy Source classification Hypericaceae Plants Other Flavonoids	Others
5-Hydroxy-1-methoxyxanthone (5-Hydroxy-1-methoxyxanthen-9-one) is a Iridoids product that can be isolated from the roots of Lamiophlomis rotata (Benth.) Kudo .

HY-135212R

Hydroxy ipronidazole (Standard)	Structural Classification Natural Products Source classification Endogenous metabolite	Endogenous Metabolite
Hydroxy ipronidazole (Standard) is the analytical standard of Hydroxy ipronidazole. This product is intended for research and analytical applications. Hydroxy ipronidazole (Ipronidazole-OH) is a metabolite of nitroimidazole antibiotics, such as ipronidazole (IPZ). Hydroxy ipronidazole may has similar mutagenic potential as the parent compound .

HY-126121R

*2-Hydroxy* Ibuprofen (Standard)**	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	COX
2-Hydroxy Ibuprofen (Standard) is the analytical standard of 2-Hydroxy Ibuprofen. This product is intended for research and analytical applications. 2-Hydroxy Ibuprofen is a metabolite of Ibuprofen. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively.

HY-W010254

*4′-Hydroxy-2′-methylacetophenone*	Infection Structural Classification Monophenols Epiphyllum oxypetalum (DC.) Haw. Cactaceae Classification of Application Fields Ketones, Aldehydes, Acids Source classification Phenols Plants Disease Research Fields	Parasite
4′-Hydroxy-2′-methylacetophenone, an aroma compound of red wines, is isolated from cv. Bobal grape variety. 4′-Hydroxy-2′-methylacetophenone has ciliate toxicity. 4′-Hydroxy-2′-methylacetophenone inhibits the growth of T. pyriformis, with an IC₅₀ of 0.65 mM .

HY-N8047

*5-Hydroxy-7-(4'-hydroxy-3'-methoxyphenyl)-1-phenyl-3-heptanone*	Structural Classification Source classification Phenols Plants Curcuma longa Zingiberaceae	Others
5-Hydroxy-7-(4'-hydroxy-3'-methoxyphenyl)-1-phenyl-3-heptanone is a Phenols product that can be isolated from the rhizomes of Curcuma longa L. .

HY-N13284

*13-Hydroxy-9-octadecenoic acid*	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Fungal
13-Hydroxy-9-octadecenoic acid is a hydroxy unsaturated fatty acid (HUFA) that has anti-fungal activity .

HY-N7602

*10-Hydroxy* majoroside**	Plantaginaceae Natural Products Classification of Application Fields Source classification Other Diseases Plantago asiatica L. Plants Disease Research Fields	Others
10-Hydroxy majoroside is a methanol extract isolated from plantago asiatica .

HY-N0445

*2-Hydroxy-4-methoxybenzaldehyde*	Structural Classification Monophenols other families Classification of Application Fields Simple Phenylpropanols Source classification Other Diseases Phenols Phenylpropanoids Plants Disease Research Fields	Tyrosinase Bacterial
2-hydroxy-4-methoxybenzaldehyde is a potent tyrosinase inhibitor . 2-Hydroxy-4-methoxybenzaldehyde, an isomer of Vanillin, could be used to synthesis Urolithin M7

HY-W001663

*4'-Hydroxy-3'-methylacetophenone*	Infection Monophenols Classification of Application Fields Ketones, Aldehydes, Acids Source classification Rubiaceae Phenols Plants Disease Research Fields Coffea arabica L.	Bacterial
4'-Hydroxy-3'-methylacetophenone, a phenolic volatile compound, is isolated from Hawaiian green coffee beans (Coffea Arabica L.). 4'-Hydroxy-3'-methylacetophenone has potent antioxidant activities. 4'-Hydroxy-3'-methylacetophenone also can be used to synthesize heterocyclic compounds which have antimycobacterial activity .

HY-N8797

*Methyl 1-hydroxy-4-oxocyclohexaneacetate*	Structural Classification Erinacea anthyllis Link Ketones, Aldehydes, Acids Source classification Plants Compositae	Others
Methyl 1-hydroxy-4-oxocyclohexaneacetate (Compound 7) is a lactone. Methyl 1-hydroxy-4-oxocyclohexaneacetate is isolated from the natural Senecio scandens. Methyl 1-hydroxy-4-oxocyclohexaneacetate has anti-inflammatory andantibacterialactivity .

HY-126121

*2-Hydroxy* Ibuprofen** (±)-2-Hydroxy Ibuprofen	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields Inflammation/Immunology	COX
2-Hydroxy Ibuprofen is a metabolite of Ibuprofen. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC₅₀s of 13 μM and 370 μM, respectively.

HY-N7971

*2-Hydroxy-1-Methoxyaporphine*	Cardiovascular Disease Alkaloids Structural Classification Monophenols Classification of Application Fields Source classification Phenols Nelumbo nucifera Gaertn. Plants Isoquinoline Alkaloids Disease Research Fields Nymphaeaceae	Endogenous Metabolite
2-Hydroxy-1-Methoxyaporphine is an alkaloid that can be isolated from Nelumbo nucifera. 2-Hydroxy-1-Methoxyaporphine is the major active ingredient of the Chinese traditional medicine Jiang-Zhi-Ning .

HY-135212

Hydroxy ipronidazole	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Hydroxy ipronidazole (Ipronidazole-OH) is a metabolite of nitroimidazole antibiotics, such as ipronidazole (IPZ). Hydroxy ipronidazole may has similar mutagenic potential as the parent compound .

HY-W016103

*1-Hydroxy-2-naphthoic acid*	Structural Classification Monophenols Classification of Application Fields Ketones, Aldehydes, Acids Source classification Phenols Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
1-Hydroxy-2-naphthoic acid is an endogenous metabolite.

HY-23195

*Potassium 2-hydroxy-2-methylsuccinate*	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Potassium 2-hydroxy-2-methylsuccinate is an endogenous metabolite.

HY-W007888

*2-Hydroxy-4-methylbenzaldehyde*	Structural Classification Monophenols Classification of Application Fields Ketones, Aldehydes, Acids Source classification Phenols Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
2-Hydroxy-4-methylbenzaldehyde is an endogenous metabolite.

HY-W008188

*3-Hydroxy-4-aminopyridine*	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
3-Hydroxy-4-aminopyridine is an endogenous metabolite.

HY-N7608

Beiwutine 10-Hydroxy mesaconitine	Alkaloids Terpenoids Source classification Ranunculaceae Diterpenoids Aconitum carmichaeli Debx. Plants	Others
Beiwutine (10-Hydroxy mesaconitine) is a diester diterpenoid alkaloid .

HY-N13543

*5-Hydroxy-7-(4-hydroxy-3-methoxyphenyl)-1-phenylhept-4-en-3-one*	Zingiber officinale Roscoe Structural Classification Source classification Phenols Polyphenols Plants Zingiberaceae	Others
5-Hydroxy-7-(4-hydroxy-3-methoxyphenyl)-1-phenylhept-4-en-3-one is a natural product .

HY-75625

*2-Hydroxy-4-methoxybenzoic acid* 4-Methoxysalicylic Acid	Monophenols other families Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Phenols Plants Disease Research Fields	Others
2-Hydroxy-4-methoxybenzoic acid is a derivative of methoxybenzoic. 2-Hydroxy-4-methoxybenzoic is a potential biomarker.

HY-N3505

*14-Hydroxy* sprengerinin C**	Classification of Application Fields Dipsacaceae Source classification Other Diseases Plants Dipsacus asper Disease Research Fields Steroids	Others
14-Hydroxy sprengerinin C is a steroidal compound found in Ophiopogon japonicus.

HY-N13416

*6-Hydroxy-7-methoxydihydroligustilide*	Structural Classification Natural Products Source classification Umbelliferae Plants Echinacea angustifolia DC.	Others
6-Hydroxy-7-methoxydihydroligustilide is a natural product .

HY-138545

*4-Hydroxy-6-methylcoumarin*	Structural Classification Ekebergia senegalensis Source classification Coumarins Phenylpropanoids Plants Meliaceae	Others
4-Hydroxy-6-methylcoumarin is a Coumarin product .

HY-N8142

*6-Hydroxy-2-phenethylchromone*	Monophenols other families Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Phenols Plants Disease Research Fields	Others
6-Hydroxy-2-phenethylchromone possesses antioxidant activity .

HY-P2274

Argifin	Infection Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields	Parasite
Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms, with IC₅₀s of 0.025 μM, 6.4 μM , 1.1 μM and 4.5 μM for SmChiA (Serratia marcescens chitinaese A), SmChiB, Aspergillus fumigatus chitinase B1 and human chitotriosidase, respectively .

HY-22167

*Methyl 2-hydroxy-4-methylvalerate*	Structural Classification Natural Products Animals Classification of Application Fields Source classification Other Diseases Disease Research Fields	Others
Methyl 2-hydroxy-4-methylvalerate is one of dominant volatile compounds in Zhenjiang aromatic vinegar. Methyl 2-hydroxy-4-methylvalerate is used for charting flavour biosynthesis networks of vinegar microbiota .

HY-N8680

*12-Hydroxy-2,3-dihydroeuparin*	Structural Classification Classification of Application Fields Ophryosporus axilliflorus Hieron. Source classification Phenols Plants Compositae Inflammation/Immunology Disease Research Fields	Others
12-Hydroxy-2,3-dihydroeuparin (compound 7) is a natural product that can be isolated from the aerial parts of Ophryosporus axilliflorus. 12-Hydroxy-2,3-dihydroeuparin shows extremely anti-inflammatory activity .

HY-N9735

*8-Hydroxy-9,10-diisobutyryloxythymol*	Structural Classification Monophenols Source classification Euchresta horsfieldii (Lesch.) J. Benn. Phenols Plants Compositae	Bacterial
8-Hydroxy-9,10-diisobutyryloxythymol is a natural monoterpenoid with antibacterial properties. 8-Hydroxy-9,10-diisobutyryloxythymol against S. aureus, S. flexneri, and S. paratyphi-B with MIC values of 6.25 μg/mL .

HY-N8114

*2-Naphthalenecarboxylic acid, 4-(D-glucopyranosyloxy)-1-hydroxy-3-(3-hydroxy-3-methylbutyl)-, methyl ester*	Quinones Monophenols Classification of Application Fields Source classification Other Diseases Rubiaceae Phenols Plants Naphthalene Quinones Disease Research Fields Rubia cordifolia L.	Others
2-Naphthalenecarboxylic acid, 4-(D-glucopyranosyloxy)-1-hydroxy-3-(3-hydroxy-3-methylbutyl)-, methyl ester (compound 3) is a natural product that can be isolated from the dried roots of Rubia cordifolia .

HY-W002587

*4-Hydroxy-3-methylbenzoic acid*	Monophenols Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Phenols Endogenous metabolite Disease Research Fields	Endogenous Metabolite
4-Hydroxy-3-methylbenzoic acid is a normal organic acid identified in urine specimens from a healthy population.

HY-N1625

*1-Hydroxy-2-methylanthraquinone*	Quinones Monophenols Classification of Application Fields Anthraquinones Source classification Rubiaceae Morinda citrifolia Linn. Phenols Plants Disease Research Fields Inflammation/Immunology	Bacterial
1-Hydroxy-2-methylanthraquinone exhibits antimicrobial, antioxidant, pesticidal, and anti-inflammatory activities .

HY-N3287

*Methyl 3-hydroxy-4,5-dimethoxybenzoate*	Infection Monophenols Classification of Application Fields Source classification Phenols Euphorbiaceae Plants Disease Research Fields Macaranga sinensis (Baill.) Muell. Arg.	Bacterial
Methyl 3-hydroxy-4,5-dimethoxybenzoate is a gallic acid derivant isolated from myricaria Laxiflora. Methyl 3-hydroxy-4,5-dimethoxybenzoate shows obvious antimicrobial activities. Methyl 3-hydroxy-4,5-dimethoxybenzoate shows fairly active for oxidation resistance in the presence of H₂O₂ .

HY-N13673

*2-Hydroxy-1,8-dimethoxyxanthone*	Structural Classification Xanthones Calophyllum membranaceum Gardner & Champ. Source classification Phenols Plants Calophyllaceae	Others
2-Hydroxy-1,8-dimethoxyxanthone is a natural product .

HY-N12004

*19-Hydroxy-10-deacetylbaccatin III*	Structural Classification Terpenoids Source classification Taxaceae Diterpenoids Plants Taxus chinensis (Pilger) Rehd.	Others
19-Hydroxy-10-deacetylbaccatin III (compound 13) is a taxane with potential antitumor activity. 19-Hydroxy-10-deacetylbaccatin III has weak cytotoxicity against A498 and NCI-H226 cell lines. The study found that the inhibition rates of 30 μg/mL 19-Hydroxy-10-deacetylbaccatin III on A498, NCI-H226 and PC-3 were 16.6% and 32% respectively .

HY-W002339

*3-Hydroxy-2-methylpyridine*	Alkaloids other families Classification of Application Fields Leguminosae Source classification Other Diseases Pyridine Alkaloids Astragalus membranaceus var. mongholicus (Bunge)P.K.Hsiao Plants Disease Research Fields	DNA/RNA Synthesis
3-Hydroxy-2-methylpyridine, isolated from alkaline extracts of cocoa, is used in the synthesis of pyrimidine .

HY-W005327

*1-Hydroxy-2-butanone*	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Bacterial Endogenous Metabolite
1-Hydroxy-2-butanone is a natural compound isolated from Bomboo Juice with antitubercular activity .

HY-N7179

*7-Hydroxy-5-methoxycoumarin*	Source classification Coumarins Phenylpropanoids Plants Convolvulaceae Ipomoea batatas (Linn.) Lamarck	Others
7-Hydroxy-5-methoxycoumarin is a phloroglucinol-type furocoumarins, a potent naturally-occurring insect antifeedant .

HY-N2748

*7-Hydroxy-3-prenylcoumarin*	Structural Classification Source classification Coriaria nepalensis Wall. Coumarins Phenylpropanoids Coriariaceae Plants	Others
7-Hydroxy-3-prenylcoumarin is a Coumarins product that can be isolated from the herbs of Coriaria nepalensis .

HY-N1588

*15-Hydroxy-7-oxodehydroabietic acid*	Structural Classification Pinaceae Terpenoids Source classification Diterpenoids Plants Pinus massoniana Lamb.	Others
15-Hydroxy-7-oxodehydroabietic acid is a Diterpenoids product that can be isolated from the herbs of Pinus massoniana .

HY-N10192

Aculene D	Infection Microorganisms Classification of Application Fields Terpenoids Sesquiterpenes Source classification Disease Research Fields	Endogenous Metabolite Bacterial
Aculene D, a fungal metabolite, shows quorum sensing (QS) inhibitory activity against Chromobacterium violaceum CV026, and could significantly reduce violacein production in N-hexanoyl-l-homoserine lactone (C6-HSL) induced C. violaceum CV026 cultures at sub-inhibitory concentrations .

HY-W011474R

Geranylgeraniol (Standard)	Structural Classification Natural Products Microorganisms	NF-κB
Geranylgeraniol (Standard) is the analytical standard of Geranylgeraniol. This product is intended for research and analytical applications. Geranylgeraniol is an orally acitve vitamin K2 sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model ^[3][4].

HY-W592871

*10-Hydroxy-2-decenoic acid* 10-HDA	Structural Classification Animals Ketones, Aldehydes, Acids Source classification	mTOR
10-Hydroxy-2-decenoic acid (10-HDA) is the major lipid component of royal jelly produced by honeybees. 10-Hydroxy-2-decenoic acid has several health-beneficial effects in mammals, such as antitumor activity, anti-inflammatory activity, and antiangiogenic activity. 10-Hydroxy-2-decenoic acid also extends the lifespan of C. elegans .

Cat. No.	Product Name	Chemical Structure

HY-B2033S1

Pyrimethanil-d5
Pyrimethanil-d₅ is the deuterium labeled Hypoxanthine. Hypoxanthine, a purine derivative, is a potential free radical generator and could be used as an indicator of hypoxia.

HY-12772S

Hydroxy Itraconazole-d8
Hydroxy Itraconazole-d₈ is the deuterium labeled Hydroxy Itraconazole. Hydroxy Itraconazole is an active metabolite of Itraconazole (ITZ), which is a triazole antifungal agent.

HY-W742358

*4'-Hydroxy* pyrimethanil-d4**
4'-Hydroxy pyrimethanil-d₄ is the deuterium labeled 4'-Hydroxy pyrimethanil. Radioactive isotopes labeled compounds can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified .

HY-121385S1

Hydroxy Bosentan-d4
Hydroxy Bosentan-d₄ is deuterium labeled Hydroxy bosentan. Hydroxy bosentan (Ro 48-5033) is a primary metabolite of Bosentan (BOS) metabolized by the cytochrome P450 system in the liver. Ro 48-5033 assists BOS pharmacologically, retaining 10%-20% activities[1].

HY-115354S

*4-Hydroxy* Alprazolam-d5**
4-Hydroxy Alprazolam-d5 (4-Hydroxyalprazolam-d5; RS-4-Hydroxyalprazolam-d5) is the deuterium labeled 4-hydroxy Alprazolam (HY-115354) .

HY-W012927S

*4-Hydroxy-5-methylfuran-3(2H)-one-d3*
4-Hydroxy-5-methylfuran-3(2H)-one-d₃ is deuterated labeled 2-Isopropyl-3-methoxypyrazine.

HY-126121S

*2-Hydroxy* Ibuprofen-d6**
2-Hydroxy Ibuprofen-d₆ is the deuterium labeled 2-Hydroxy Ibuprofen. 2-Hydroxy Ibuprofen is a metabolite of Ibuprofen. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively[1][2].

HY-G0003S1

*Iloperidone metabolite Hydroxy* Iloperidone-d3**
Iloperidone metabolite Hydroxy Iloperidone-d₃ is the deuterium labeled Iloperidone metabolite Hydroxy Iloperidone[1].

HY-12773AS2

*5-Hydroxy* Propafenone-d6 hydrochloride**
5-Hydroxy Propafenone-d₆ hydrochloride is deuterated labeled 5-Hydroxy Propafenone.

HY-10844S1

Pretomanid-d5
Pretomanid-d₅ is deuterated labeled Pretomanid (HY-10844). Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 μg/mL.

HY-W010305S

*5-Ethyl-3-hydroxy-4-methylfuran-2(5H)-one-d4*
5-Ethyl-3-hydroxy-4-methylfuran-2(5H)-one-d₄ is deuterated labeled 6-Heptyltetrahydro-2H-pyran-2-one.

HY-131543S

*22-Hydroxy* Mifepristone-d6**
22-Hydroxy Mifepristone-d₆ is the deuterium labeled 22-Hydroxy Mifepristone[1]. 22-Hydroxy Mifepristone-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W025101S

*Ethyl 3-hydroxy-3-methylbutanoate-d6*
Ethyl 3-hydroxy-3-methylbutanoate-d₆ is the deuterium labeled Ethyl 3-hydroxy-3-methylbutanoate[1].

HY-111975S1

*7'-Hydroxy* ABA-d2**
7'-Hydroxy ABA-d₂2 is the deuterium labeled 7'-Hydroxy ABA[1].

HY-111975S5

*7'-Hydroxy* ABA-d7**
7'-Hydroxy ABA-d₇ is the deuterium labeled 7'-Hydroxy ABA[1].

HY-151930S

*8′-Hydroxy* ABA-d8**
8′-Hydroxy ABA-d₈ is the deuterium labeled 8’-Hydroxy ABA[1].

HY-151930S1

*8′-Hydroxy* ABA-d2**
8′-Hydroxy ABA-d₂ is the deuterium labeled 8’-Hydroxy ABA[1].

HY-108263S

*3-Hydroxy* Midostaurin-d5**
3-Hydroxy Midostaurin-d₅ is a deuterium labeled 3-Hydroxy Midostaurin. 3-Hydroxy Midostaurin is a metabolite of PKC412, which effectively inhibits FMS-like tyrosine kinase-3 (FLT3) autophosphorylation with IC50s of approximately 132 nM and 9.8 μM in culture medium and plasma, respectively[1].

HY-W008216S

HMMNI-d3
HMMNI-d₃ is deuterium labeled HMMNI. HMMNI (Hydroxy dimetridazole) is a hydroxy metabolite of Dimetridazole. Dimetridazole is a nitroimidazole class agent that combats protozoan infections[1].

HY-B0151S

Pregnenolone-d4

Pregnenolone-d₄ is the deuterium labeled Pregnenolone. Pregnenolone (3β-Hydroxy-5-pregnen-20-one) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone can protect the brain from cannabis intoxication[1][2]. Pregnenolone is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels[3].

HY-121385S

Hydroxy Bosentan-d6
Hydroxy Bosentan-d₆ is deuterium labeled Hydroxy bosentan. Hydroxy bosentan (Ro 48-5033) is a primary metabolite of Bosentan (BOS) metabolized by the cytochrome P450 system in the liver. Ro 48-5033 assists BOS pharmacologically, retaining 10%-20% activities[1].

HY-113038AS1

α-Hydroxyglutaric acid-d4 disodium

α-Hydroxyglutaric acid-d₄ (disodium) is the deuterium labeled α-Hydroxyglutaric acid disodium[1]. α-Hydroxyglutaric acid (2-Hydroxyglutarate) disodium is an α-hydroxy acid form of glutaric acid. α-Hydroxyglutaric acid disodium is a competitive inhibitor of multiple α-ketoglutarate-dependent dioxygenases, including histone demethylases and the TET family of 5-methlycytosine (5mC) hydroxylases[2].

HY-W354610S

*N-(4-Hydroxy-3-methoxybenzyl)stearamide-d3*
N-(4-Hydroxy-3-methoxybenzyl)stearamide-d₃ is the deuterium labeled N-(4-hydroxy-3-methoxybenzyl)stearamide[1].

HY-41680S

4-Aminobenzonitrile-d4
4-Aminobenzonitrile-d₄ is the deuterium labeled 4-Aminobenzonitrile[1].

HY-66005S

Acetaminophen-d4
Acetaminophen-d₄ is the deuterium labeled Acetaminophen. Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM; is a widely used antipyretic and analgesic agent[1][2][3]. Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor[4].

HY-12773AS

*5-Hydroxy* Propafenone-d5 hydrochloride**
5-Hydroxy Propafenone-d₅ (hydrochloride) is the deuterium labeled 5-Hydroxy Propafenone.

HY-B1159S

Nitroxoline-D4
Nitroxoline-d₄ is the deuterium labeled Nitroxoline. Nitroxoline is an antibiotic that has proven to be very effective at combating biofilm infections. Nitroxoline functions by chelating Fe2+ and Zn2+ ions from the biofilm matrix[1][2].

HY-B0151S2

Pregnenolone-d4-1

Pregnenolone-d₄-1 is the deuterium labeled Pregnenolone. Pregnenolone (3β-Hydroxy-5-pregnen-20-one) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone can protect the brain from cannabis intoxication[1][2]. Pregnenolone is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels[3].

HY-118714S

*α-Hydroxy* alprazolam-d5**
α-Hydroxy alprazolam-d₅ (U 40125-d₅; alpha-Hydroxyalprazolam-d₅) is the deuterium labled α-hydroxy alprazolam (HY-118714).

HY-110189S1

Pregnenolone monosulfate-d4 sodium

Pregnenolone monosulfate-d₄ (sodium) is the deuterium labeled Pregnenolone monosulfate. Pregnenolone monosulfate sodium (3β-Hydroxy-5-pregnen-20-one monosulfate sodium) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone monosulfate sodium acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone monosulfate sodium can protect the brain from cannabis intoxication[1][2]. Pregnenolone monosulfate sodium is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels[3].

HY-Y1042S

4-Cyanophenol-d4
4-Cyanophenol-d₄ is the deuterium labeled 4-Cyanophenol[1].

HY-17461S3

Cortisone-d2
Cortisone-d₂ is the deuterium labeled Cortisone. Cortisone (17-Hydroxy-11-dehydrocorticosterone), an oxidized metabolite of Cortisol (a Glucocorticoid). Cortisone acts as an immunosuppressant and anti-inflammatory agent. Cortisone can partially intervene in binding of Glucocorticoid to Glucocorticoid-receptor at high concentrations[1][3][4][5].

HY-100634SA

4-Hydroxypropranolol-d7

4-Hydroxypropranolol-d₇ is the deuterium labeled 4-Hydroxypropranolol hydrochloride. 4-Hydroxypropranolol hydrochlorid is an active metabolite of Propranolol. 4-Hydroxypropranolol hydrochlorid is of comparable potency to Propranolol. 4-Hydroxypropranolol hydrochlorid inhibits β1- and β2-adrenergic receptors with pA2 values of 8.24 and 8.26, respectively. 4-Hydroxypropranolol hydrochlorid has intrinsic sympathomimetic activity, membrane stabilizing activity and potent antioxidant properties[1][2][3].

HY-17413S2

Zidovudine-d4
Zidovudine-d₄ is deuterated labeled Zidovudine (HY-17413). Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection. Zidovudine increases CRISPR/Cas9-mediated editing frequency.

HY-32351AS

Calcifediol-d6 monohydrate
Calcifediol-d₆ monohydrate is the deuterium labeled Calcifediol monohydrate. Calcifediol monohydrate (25-hydroxy Vitamin D3 monohydrate), is an effective VDR ligand and VD supplement. Calcifediol is a prohormone of the vitamin D endocrine system (VDES) and is hydroxylated in the liver to produce the active form, calcitriol. Calcifediol can rapidly increase serum VD levels .

HY-B1008S

4-Aminobenzoic acid-d4
4-Aminobenzoic acid-d₄ is the deuterium labeled 4-Aminobenzoic acid. 4-Aminobenzoic acid is an intermediate in the synthesis of folate by bacteria, plants, and fungi.

HY-N0006S1

Demethoxycurcumin-d4
Demethoxycurcumin-d₄ is the deuterium labeled Demethoxycurcumin. Demethoxycurcumin (Curcumin II) is a major active curcuminoid; possess anti-inflammatory properties[1].

HY-B0329S

Isoniazid-d4
Isoniazid-d₄ is the deuterium labeled Isoniazid. Isoniazid (INH) is a proagent and must be activated by a bacterial catalase-peroxidase enzyme KatG. Isoniazid is bactericidal to rapidly dividing mycobacteria and has anti-tuberculostatic activity[1][2][3][4].

HY-100048S

Acetylisoniazid-d4
Acetylisoniazid-d₄ is the deuterium labeled Acetylisoniazid[1].

HY-118861S

Enclomiphene-d4 hydrochloride
Enclomiphene-d₄ (hydrochloride) is a deuterium labeled Enclomiphene. Enclomiphene-d₄ (hydrochloride) is a potent and orally active oestrogen receptor antagonist, with antioestrogenic property[1].

HY-109015S

Tucidinostat-d4
Tucidinostat-d₄ is the deuterium labeled Tucidinostat. Tucidinostat is a potent and orally bioavailable HDAC enzymes class I (HDAC1/2/3) and class IIb (HDAC10) inhibitor, with IC50s of 95, 160, 67 and 78 nM, respectively[1].

HY-19696AS

Tauroursodeoxycholate-d4 sodium
Tauroursodeoxycholate-d₄ (sodium) is the deuterium labeled Tauroursodeoxycholate sodium. Tauroursodeoxycholate (Tauroursodeoxycholic acid; TUDCA) sodium is an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12. Tauroursodeoxycholate also inhibits ERK.

HY-19696S1

Tauroursodeoxycholate-d4
Tauroursodeoxycholate-d₄ is deuterium labeled Tauroursodeoxycholate. Tauroursodeoxycholate (Tauroursodeoxycholic acid) is an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12. Tauroursodeoxycholate also inhibits ERK.

HY-B0389S24

D-Glucose-d4
D-Glucose-d₄ is the deuterium labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molec

HY-B0696AS

Tiagabine-d4 hydrochloride
Tiagabine-d₄ hydrochloride is deuterated labeled Tiagabine hydrochloride (HY-B0696A). Tiagabine hydrochloride is a potent and selective GABA reuptake inhibitor, used as an anticonvulsant agent, with IC₅₀s of 67, 446 and 182 nM for [ ³H]GABA uptake in Synaptosomes, Neurons and Glia, respectively .

HY-13273S

Ostarine-d4
Ostarine-d4 is a deuterated labeled Ostarine .

HY-34498S

4-Chloro-2-methylphenol-d4
4-Chloro-2-methylphenol-d₄ is the deuterium labeled 4-Chloro-2-methylphenol[1].

HY-107542S

Oleoylethanolamide-d4
Oleoylethanolamide-d₄ is the deuterium labeled Oleoylethanolamide. Oleoylethanolamide is a high affinity endogenous PPAR-α agonist, which plays an important role in the treatment of obesity and arteriosclerosis.

HY-B0017S

Telbivudine-d4
Telbivudine-d₄ is deuterium labeled Telbivudine. Telbivudine (Epavudine), an orally active thymidine nucleoside analog, is a potent antiviral inhibitor of hepatitis B virus (HBV) replication[1].

HY-B0579S

Cyclosporin A-d4
Cyclosporin A-d₄ is the deuterium labeled Cyclosporin A. Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of calcineurin with an IC50 of 5 nM. Cyclosporin A also inhibits CD11a/CD18 ad

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Species:	Human (16)
Tag:	GFP (3) His (15) Strep (5) Myc (1) Trx (1) Flag (7)
Source:	HEK293 (10) E. coli Cell-free (1) E. coli (5)


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4'-Hydroxy pyrimethanil-d<sub>4</sub>

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