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DMABA-d<sub>6</sub> NHS ester

" in MedChemExpress (MCE) Product Catalog:

3653

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133

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49

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17

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1

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2

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48

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13

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2900

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156

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Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-118431
    DMABA NHS ester

    		Others Others
    DMABA NHS ester can chemically react with the primary amine groups of the major phospholipid component of the cell membrane, Phosphatidylethanolamine (PE). Through precursor ion scanning, all PE subclasses labeled with DMABA can be detected. DMABA NHS ester can be used in combination with isotope-labeled compounds such as DMABA-d6 NHS ester, DMABA-d10 NHS ester, and DMABA-d4 NHS ester to observe changes in the distribution of PE lipids and the formation of novel PE lipid products .
    DMABA NHS ester
  • HY-118431S2
    DMABA-d6 NHS ester

    		Isotope-Labeled Compounds Others
    DMABA-d6 NHS ester is the deuterium labeled DMABA NHS ester[1].
    DMABA-d6 NHS ester
  • HY-118431S3
    DMABA-d10 NHS ester

    		Isotope-Labeled Compounds Others
    DMABA-d10 NHS ester is the deuterium labeled DMABA NHS ester[1].
    DMABA-d10 NHS ester
  • HY-118431S
    DMABA-d4 NHS ester

    		Isotope-Labeled Compounds Others
    DMABA-d4 NHS ester is the deuterium labeled DMABA NHS ester[1].
    DMABA-d4 NHS ester
  • HY-D1730
    AF488 NHS ester

    		Fluorescent Dye Others
    AF488 NHS ester is an amine specific fluorescence probe (Em=525 nm). AF488 NHS ester reacts with sulfhydryl groups and amines in aqueous and biological samples then change their chemical structure and fluorescence properties after derivatization .
    AF488 NHS ester
  • HY-D2291
    BODIPY TMR NHS ester

    		Fluorescent Dye Others
    BODIPY TMR NHS ester is bright, orange fluorescent dye with Ex/Em of 544/570 nm. The NHS ester (or succinimidyl ester) of BODIPY TMR NHS ester is a popular tool for conjugating the dye to a protein or antibody. NHS esters can be used to label the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules .
    BODIPY TMR NHS ester
  • HY-RS13999
    SUB1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    SUB1 Human Pre-designed siRNA Set A contains three designed siRNAs for SUB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    SUB1 Human Pre-designed siRNA Set A
    SUB1 Human Pre-designed siRNA Set A
  • HY-146227
    DNA topoisomerase II inhibitor 1

    		Topoisomerase Apoptosis Cancer
    DNA topoisomerase II inhibitor 1 (compound 8ed) is a potent DNA topoisomerase II inhibitor. DNA topoisomerase II inhibitor 1 shows anti-proliferative activity. DNA topoisomerase II inhibitor 1 induces apoptosis and cell cycle arrest at sub G1 phase .
    DNA topoisomerase II inhibitor 1
  • HY-141166A
    (S,E)-TCO2-PEG3-NHS ester

    		Biochemical Assay Reagents Cancer
    (S,E)-TCO2-PEG3-NHS ester is NH2 reactive, and can be used in chemical synthesis. (S,E)-TCO2-PEG3-NHS ester contains TCO groups, which can undergo specific "click" reactions with tetrazine groups .
    (S,E)-TCO2-PEG3-NHS ester
  • HY-D2290
    Demethoxy-BODIPY TMR NHS ester

    		Fluorescent Dye Others
    Demethoxy-BODIPY TMR NHS ester is an amine-reactive fluorescent probe, and can be used for the labeling of proteins, peptides, and other molecules .
    Demethoxy-BODIPY TMR NHS ester
  • HY-D1568
    Sulfo-Cy7.5 NHS ester

    		Fluorescent Dye Others
    Sulfo-Cy7.5 NHS ester is a near infrared water soluble hydrophilic dye, also is an NHS ester for the modification of amine groups. Sulfo-Cy7.5 NHS ester contains a trimeth ylene bridge and has a linker arm for its attachment to proteins, peptides, and other molecules. Sulfo-Cy7.5 NHS ester can be used for the research of NIR imaging applications .
    Sulfo-Cy7.5 NHS ester
  • HY-D2178
    AF 568 NHS ester

    		Fluorescent Dye Others
    AF 568 NHS ester is a derivative of the orange fluorescent dye AF 568. AF 568 NHS ester is widely used in cell dyes, biological dyes, biomolecules and particle fluorescent labeling. AF 568 exhibits maximum absorption wavelength of 579 nm and the maximum emission wavelength of 603 nm .
    AF 568 NHS ester
  • HY-D1567
    Cy7.5 NHS ester

    		Fluorescent Dye Others
    Cy7.5 NHS ester is a fluorescent dye. Cy7.5 NHS ester can be conjugated to mPEG-b-PDPA to form a mPEG-b-PDPA-Cy7.5 fluorescent copolymer. Cy7.5 NHS ester can be used for fluorescent imaging study .
    Cy7.5 NHS ester
  • HY-10844S1
    Pretomanid-d5

    PA-824-d<sub>5sub>; (S)-PA 824-d<sub>5sub>

    		 Antibiotic Bacterial Isotope-Labeled Compounds Infection Cancer
    Pretomanid-d5 is deuterated labeled Pretomanid (HY-10844). Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 μg/mL.
    Pretomanid-d5
  • HY-160773
    DBCO-PEG6-NHS ester

    		Biochemical Assay Reagents Others
    DBCO-PEG6-NHS ester is a click chemistry PEG reagent containing an NHS ester that reacts specifically with primary amines, such as side chains of lysine residues or aminosilane-coated surfaces, under neutral or slightly alkaline conditions. , efficient reaction to form covalent bonds. DBCO-PEG6-NHS ester also contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
    DBCO-PEG6-NHS ester
  • HY-164165
    Paclitaxel-2′-succinate NHS ester

    		Others Cancer
    Paclitaxel-2′-succinate NHS ester is a paclitaxel derivative with a succinic acid linker, in which the carboxyl group is activated by the NHS ester. The NHS ester group is highly reactive toward amino or hydroxyl groups and can be used to conjugate with other molecules such as peptides, proteins, antibodies, enzymes or polymers. Paclitaxel-2′-succinate NHS ester can be used in the development of nanomedicines and in the study of cancer therapy .
    Paclitaxel-2′-succinate NHS ester
  • HY-B0715S
    Pentoxifylline-d6

    BL-191-d<sub>6sub>; PTX-d<sub>6sub>; Oxpentifylline-d<sub>6sub>

    		 Phosphodiesterase (PDE) Autophagy HIV Cardiovascular Disease Cancer
    Pentoxifylline-d6 is the deuterium labeled Pentoxifylline. Pentoxifylline (BL-191), a haemorheological agent, is an orally active non-selective phosphodiesterase (PDE) inhibitor, with immune modulation, anti-inflammatory, hemorheological, anti-fibrinolytic and anti-proliferation effects. Pentoxifylline can be used for the research of peripheral vascular disease, cerebrovascular disease and a number of other conditions involving a defective regional microcirculation[1][2][3].
    Pentoxifylline-d6
  • HY-15494S1
    Picropodophyllin-d6

    AXL1717-d<sub>6sub>; Picropodophyllotoxin-d<sub>6sub>; PPP-d<sub>6sub>

    		 Isotope-Labeled Compounds IGF-1R Apoptosis Endocrinology Cancer
    Picropodophyllin-d6 (AXL1717-d6) is deuterium labeled Picropodophyllin. Picropodophyllin (AXL1717) is a selective insulin-like growth factor-1 receptor (IGF-1R) inhibitor with an IC50 of 1 nM.
    Picropodophyllin-d6
  • HY-B1873S
    Methoxychlor-d6

    DMDT-d<sub>6sub>; Methoxcide-d<sub>6sub>; Methoxy-DDT-d<sub>6sub>

    		 Isotope-Labeled Compounds Others
    Methoxychlor-d6 is the deuterium labeled Methoxychlor[1].
    Methoxychlor-d6
  • HY-D1119C
    AF647-NHS ester triTEA

    		Fluorescent Dye Others
    AF647-NHS ester is an analogue of Alexa Fluor 647 (AF647), which has excitation wavelength (λex) of 635 nm (conventional fluorescence detection)/620 nm (instantaneous detection) .
    AF647-NHS ester triTEA
  • HY-B0236S
    6-Aminocaproic acid-d6

    EACA-d<sub>6sub>; Epsilon-Amino-n-caproic acid-d<sub>6sub>; 6-Aminohexanoic acid-d<sub>6sub>

    		 Isotope-Labeled Compounds Metabolic Disease
    6-Aminocaproic acid-d6 is deuterium labeled 6-Aminocaproic acid. 6-Aminocaproic acid (EACA), a monoamino carboxylic acid, is a potent and orally active inhibitor of plasmin and plasminogen. 6-Aminocaproic acid is a potent antifibrinolytic agent. 6-Aminocaproic acid prevents clot lysis through the competitive binding of lysine residues on plasminogen, inhibiting plasmin formation and reducing fibrinolysis. 6-Aminocaproic acid can be used for the research of bleeding disorders[1][2].
    6-Aminocaproic acid-d6
  • HY-76542S
    Vitamin D2-d6

    Ergocalciferol-d<sub>6sub>; Calciferol-d<sub>6sub>; Ercalciol-d<sub>6sub>

    		 VD/VDR Endogenous Metabolite Metabolic Disease
    Vitamin D2-d6 is the deuterium labeled Vitamin D2. Vitamin D2 (Ergocalciferol), drived from plant sources or dietary supplements, could be used as supplement of Vitamin D[1][2].
    Vitamin D2-d6
  • HY-N0537S9
    Xylose-d6

    D-(+)-Xylose-d<sub>6sub>; (+)-Xylose-d<sub>6sub>; Wood sugar-d<sub>6sub>

    		 Isotope-Labeled Compounds Endogenous Metabolite Others
    Xylose-d6 is the deuterium labeled Xylose.
    Xylose-d6
  • HY-N1214S
    Squalene-d6

    Super Squalene-d<sub>6sub>; trans-Squalene-d<sub>6sub>; AddaVax-d<sub>6sub>

    		 Isotope-Labeled Compounds Others
    Squalene-d6 is a deuterium labeled Squalene. Squalene (Super Squalene) is an intermediate product in the synthesis of cholesterol, and shows several pharmacological properties such as hypolipidemic, hepatoprotective, antiatherosclerotic, cardioprotective, antioxidant, and antitumour activity .
    Squalene-d6
  • HY-41681S
    6-Chloro-1-hexanol-d6

    1-Chloro-6-hexanol-d<sub>6sub>; 1-Chloro-6-hydroxyhexane-d<sub>6sub>; 6-Chlorohexanol-d<sub>6sub>

    		 Isotope-Labeled Compounds Others
    6-Chloro-1-hexanol-d6 is the deuterium labeled 6-Chloro-1-hexanol[1].
    6-Chloro-1-hexanol-d6
  • HY-19655S
    Cethromycin-d6

    ABT-773-d<sub>6sub>; Abbott-195773-d<sub>6sub>; A-195773-d<sub>6sub>

    		 Bacterial Isotope-Labeled Compounds Inflammation/Immunology
    Cethromycin-d6 (ABT-773-d6; Abbott-195773-d6; A-195773-d6) is deuterium-labeled Cethromycin (HY-19655) .
    Cethromycin-d6
  • HY-12008S
    Erlotinib-d6 hydrochloride

    CP-358774-d<sub>6sub> hydrochloride; NSC 718781-d<sub>6sub> hydrochloride; OSI-774-d<sub>6sub> hydrochloride

    		 EGFR Autophagy Cancer
    Erlotinib-d6 (hydrochloride) a deuterium labeled Erlotinib Hydrochloride. Erlotinib Hydrochloride inhibits purified EGFR kinase with an IC50 of 2 nM[1]. Erlotinib-d6 (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Erlotinib-d6 hydrochloride
  • HY-50896S
    Erlotinib-d6

    CP-358774-d<sub>6sub>; NSC 718781-d<sub>6sub>; OSI-774-d<sub>6sub>

    		 EGFR Cancer
    Erlotinib-d6 (CP-358774 D6) is a deuterium labeled Erlotinib (CP-358774). Erlotinib is a directly acting inhibitor EGFR tyrosine kinase inhibitor with an IC50 of 2 nM for human EGFR[1]. Erlotinib-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Erlotinib-d6
  • HY-N0005S
    Curcumin-d6

    Diferuloylmethane-d<sub>6sub>; Natural Yellow 3-d<sub>6sub>; Turmeric yellow-d<sub>6sub>

    		 Keap1-Nrf2 Ferroptosis Autophagy Histone Acetyltransferase Epigenetic Reader Domain Mitophagy Influenza Virus Infection Metabolic Disease Inflammation/Immunology
    Curcumin-d6is a deuterium labeled Curcumin (Turmeric yellow). Curcumin (Turmeric yellow) is a natural phenolic compound with diverse pharmacologic effects including anti-inflammatory, antioxidant, antiproliferative and antiangiogenic activities. Curcumin is an inhibitor of p300 histone acetylatransferase (HATs) and also shows inhibitory effects on NF-κB and MAPKs.
    Curcumin-d6
  • HY-12176AS
    Aliskiren-d6 hydrochloride

    CGP 60536-d<sub>6sub> Hydrochloride; CGP60536Bd<sub>6sub> Hydrochloride; SPP 100d<sub>6sub>(Hydrochloride)

    		 Isotope-Labeled Compounds Renin Cardiovascular Disease Cancer
    Aliskiren-d6 (hydrochloride) is is deuterium labeled Aliskiren, which is a direct renin inhibitor.
    Aliskiren-d6 hydrochloride
  • HY-13011S1
    Alectinib-d6

    CH5424802-d<sub>6sub>; RO5424802-d<sub>6sub>; AF802-d<sub>6sub>

    		 Isotope-Labeled Compounds Anaplastic lymphoma kinase (ALK) Cancer
    Alectinib-d6 is deuterium labeled Alectinib. Alectinib (CH5424802) is a potent, selective, and orally available ALK inhibitor with an IC50 of 1.9 nM and a Kd value of 2.4 nM (in an ATP-competitive manner), and also inhibits ALK F1174L and ALK R1275Q with IC50s of 1 nM and 3.5 nM, respectively[1]. Alectinib demonstrates effective central nervous system (CNS) penetration[2].
    Alectinib-d6
  • HY-100977S
    Dimethoxycurcumin-d6

    DiMC-d<sub>6sub>; CHC 004-d<sub>6sub>; Di-O-methylcurcumin-d<sub>6sub>

    		 Isotope-Labeled Compounds Inflammation/Immunology
    Dimethoxycurcumin-d6 is the deuterium labeled Dimethoxycurcumin (HY-100977). Dimethoxycurcumin is a derivative of Curcumin that has anti-inflammatory and antioxidant activities .
    Dimethoxycurcumin-d6
  • HY-N0113BS
    Hordenine-d6 hydrochloride

    Ordenina-d<sub>6sub> hydrochloride; Peyocactine-d<sub>6sub> hydrochloride

    		 Antibiotic Isotope-Labeled Compounds Infection
    Hordenine-d6 (Ordenina-d6; Peyocactine-d6) hydrochloride is deuterium-labeled Hordenine (hydrochloride) (HY-N0113B) .
    Hordenine-d6 hydrochloride
  • HY-N0113S
    Hordenine-d6

    Ordenina-d<sub>6sub>; Peyocactine-d<sub>6sub>

    		 Isotope-Labeled Compounds Bacterial Antibiotic Infection Cardiovascular Disease
    Hordenine-d6 (Ordenina-d6) is the deuterium labeled Hordenine. Hordenine, an alkaloid found in plants, inhibits melanogenesis by suppression of cyclic adenosine monophosphate (cAMP) production .
    Hordenine-d6
  • HY-B0971S
    Pheniramine-d6 maleate

    Prophenpyridamine-d<sub>6sub> maleate; Tripoton-d<sub>6sub> maleate

    		 Isotope-Labeled Compounds Histamine Receptor Inflammation/Immunology Endocrinology
    Pheniramine-d6 (maleate) is the deuterium labeled Pheniramine maleate. Pheniramine Maleate ia an antihistamine and vasoconstrictor.
    Pheniramine-d6 maleate
  • HY-N0283S
    Diacerein-d6

    Diacerhein-d<sub>6sub>; Diacetylrhein-d<sub>6sub>

    		 Interleukin Related Inflammation/Immunology
    Diacerein-d6 is the deuterium labeled Diacerein[1]. Diacerein (Diacerhein), a interleukin-1 beta inhibitor, is a slow-acting medicine of the class anthraquinone used to treat joint diseases[2].
    Diacerein-d6
  • HY-Y0504S4
    Trimethylammonium chloride-d6

    Hegzadesil-d<sub>6sub>; Trimethylamine hydrochloric acid-d<sub>6sub>; Trimethylamine monohydrochloride-d<sub>6sub>

    		 Endogenous Metabolite Metabolic Disease
    Trimethylammonium chloride-d6 is the deuterium labeled Trimethylammonium chloride[1]. Trimethylammonium chloride is an endogenous metabolite.
    Trimethylammonium chloride-d6
  • HY-B0005S1
    Toremifene-d6 hydrochloride

    Z-Toremifene-d<sub>6sub> hydrochloride; NK 622-d<sub>6sub> hydrochloride; FC-1157a-d<sub>6sub> hydrochloride

    		 Isotope-Labeled Compounds Estrogen Receptor/ERR Infection
    Toremifene-d6 (Z-Toremifene-d6) hydrochloride is deuterium labeled Toremifene. Toremifene is a second-generation selective estrogen-receptor modulator (SERM) in development for the prevention of osteoporosis. Toremifene also potent inhibits infectious EBOV Zaire and Marburg (MARV) with IC50 of 0.07 µM and 2.6 µM, respectively .
    Toremifene-d6 hydrochloride
  • HY-19489S
    (±)-Levomepromazine-d6

    (±)-Methotrimeprazine-d<sub>6sub>; dl-Methotrimeprazine-d<sub>6sub>

    		 Dopamine Receptor Histamine Receptor Neurological Disease
    (±)-Levomepromazine-d6 is the deuterium labeled Methotrimeprazine, which is a D3 dopamine and Histamine H1 receptor antagonist.
    (±)-Levomepromazine-d6
  • HY-90001S
    Ritonavir-d6

    ABT 538-d<sub>6sub>; RTV-d<sub>6sub>

    		 HIV Protease HIV SARS-CoV Apoptosis Infection
    Ritonavir-d6 is the deuterium labeled Ritonavir. Ritonavir (ABT 538) is an inhibitor of HIV protease used to treat HIV infection and AIDS. Ritonavir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 1.61 μM[1][2].
    Ritonavir-d6
  • HY-15772S
    Osimertinib-d6

    AZD-9291-d<sub>6sub>; Mereletinib-d<sub>6sub>

    		 EGFR Cancer
    Osimertinib-d6 is a deuterium labeled osimertinib. Osimertinib is a covalent, orally active, irreversible, and mutant-selective EGFR inhibitor with an apparent IC50 of 12 nM against L858R and 1 nM against L858R/T790M. Osimertinib overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer[1].
    Osimertinib-d6
  • HY-B1438S
    Canrenone-d6

    Aldadiene-d<sub>6sub>; SC9376-d<sub>6sub>

    		 Isotope-Labeled Compounds Mineralocorticoid Receptor Endogenous Metabolite Cardiovascular Disease
    Canrenone-d6 is the deuterium labeled Canrenone. Canrenone (Aldadiene) is an aldosterone antagonist extensively used as a diuretic agent.
    Canrenone-d6
  • HY-N0614S
    Sucralose-d6

    E955-d<sub>6sub>; Trichlorosucrose-d<sub>6sub>

    		 Endogenous Metabolite Cancer
    Sucralose-d6 is deuterium labeled Sucralose. Sucralose (E955; Trichlorosucrose) is a non-nutritive artificial sweetener and sugar substitute. Sucralose can activate a conserved neural fasting response and thereby exerts an appetite-stimulating effect in rodents[1][2].
    Sucralose-d6
  • HY-116152S
    Cipepofol-d6

    Ciprofol-d<sub>6sub>; HSK3486-d<sub>6sub>

    		 Isotope-Labeled Compounds GABA Receptor Neurological Disease
    Cipepofol-d6 (Ciprofol-d6; HSK3486-d6) is deuterium labeled Cipepofol (HY-116152). Cipepofol (HSK3486), a psychomotor stabilizing agent, is a gamma-aminobutyric acid (GABA) receptor potentiator.
    Cipepofol-d6
  • HY-15459S
    Cabazitaxel-d6

    XRP6258-d<sub>6sub>; RPR-116258A-d<sub>6sub>; taxoid XRP6258-d<sub>6sub>

    		 Microtubule/Tubulin Autophagy Cancer
    Cabazitaxel-d6 is the deuterium labeled Cabazitaxel. Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity[1][2].
    Cabazitaxel-d6
  • HY-B0457S1
    Clomipramine-d6 hydrochloride

    Chlorimipramine-d<sub>6sub> (hydrochloride); G-34586-d<sub>6sub> (hydrochloride); NSC-169865-d<sub>6sub> (hydrochloride)

    		 Serotonin Transporter Neurological Disease
    Clomipramine-d6 (hydrochloride) is the deuterium labeled Clomipramine hydrochloride. Clomipramine (Chlorimipramine) hydrochloride is a potent 5-HT reuptake blocker with the IC50 value of 1.5 nM. Clomipramine hydrochloride is a tricyclic antidepressant that can be used for the research of depression and obsessive compulsive disorder (OCD)[1].
    Clomipramine-d6 hydrochloride
  • HY-145090
    DBCO-N-bis(PEG4-NHS ester)

    		PROTAC Linkers ADC Linker Others
    DBCO-N-bis(PEG4-NHS ester) is a PEG linker which contains two PEG4-NHS ester and a DBCO group. DBCO-N-bis(PEG4-NHS ester) is useful for protein modification or labeling. DBCO-N-bis(PEG4-NHS ester) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
    DBCO-N-bis(PEG4-NHS ester)
  • HY-D1352
    Sulfo-Cyanine7 NHS ester potassium

    		Fluorescent Dye Others
    Sulfo-Cyanine7 NHS ester potassium is an amine-reactive succinimide ester. Sulfo-Cyanine7 NHS ester reagent allows to prepare sulfo-Cyanine7-labeled biomolecules, such as proteins, with ease. Dye labeled molecules can be subsequently used for various research and agent design related experiments.
    Sulfo-Cyanine7 NHS ester potassium
  • HY-N0488S2
    Vincristine-d6 sulfate

    Leurocristine-d<sub>6sub> sulfate; NSC-67574-d<sub>6sub> sulfate; 22-Oxovincaleukoblastine-d<sub>6sub> sulfate

    		 Isotope-Labeled Compounds Microtubule/Tubulin Apoptosis Cancer
    Vincristine-d6 (sulfate) is the deuterium labeled Vincristine sulfate. Vincristine sulfate is an antitumor vinca alkaloid which inhibits microtubule formation in mitotic spindle, resulting in an arrest of dividing cells at the metaphase stage. It binds to microtubule with a Ki of 85 nM.
    Vincristine-d6 sulfate
  • HY-14649S3
    Retinoic acid-d6

    Vitamin A acid-d<sub>6sub>; all-trans-Retinoic acid-d<sub>6sub>; ATRA-d<sub>6sub>

    		 RAR/RXR PPAR Autophagy Endogenous Metabolite Cancer
    Retinoic acid-d6 is the deuterium labeled Retinoic acid[1]. Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha[2][3][4][5][6][7].
    Retinoic acid-d6

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