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β-Sitosterol-d<sub>7</sub> (Mixture of Diastereomers)

" in MedChemExpress (MCE) Product Catalog:

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Click Chemistry:	Azide (3) Alkynes (17)
Oligonucleotides:	Nucleosides and their Analogs (1) Aptamers (1) Pre-designed siRNA Sets (1) Emulsifiers (1) Cationic Lipids (4) Phospholipids (1) Antisense Oligonucleotides (1) siRNAs (1)

3430

Inhibitors & Agonists

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Fluorescent Dye

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Peptides

MCE Kits

Inhibitory Antibodies

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Products

173

Recombinant Proteins

2912

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Oligonucleotides

Targets Recommended: Nuclear Factor of activated T Cells (NFAT) P-glycoprotein

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-132382S

β-Sitosterol-d7 (mixture of diasteromers)	Isotope-Labeled Compounds	Others
β-Sitosterol-d₇ (Mixture of Diastereomers) is the deuterium labeled β-Sitosterol (mixture of diasteromers)[1].

HY-132676S

*Ramiprilat-d5 (Mixture* of Diastereomers)**	Isotope-Labeled Compounds	Others
Ramiprilat-d₅ (Mixture of Diastereomers) is the deuterium labeled Ramiprilat (Mixture of Diastereomers)[1].

HY-W653769

*Deltamethrin-d5 (Mixture* of Diastereomers)**	Isotope-Labeled Compounds	Others
Deltamethrin-d5 (Mixture of Diastereomers) is the deuterium labeled Deltamethrin (Mixture of Diastereomers) .

HY-132706S

*N-Deformyl Formoterol-d6 Fumarate (Mixture* of Diastereomers)**	Isotope-Labeled Compounds	Others
N-Deformyl Formoterol-d₆ Fumarate (Mixture of Diastereomers) is the deuterium labeled N-Deformyl Formoterol Fumarate (Mixture of Diastereomers)[1].

HY-134670S

*α-Hydroxy Metoprolol-d5 (Mixture* of Diastereomers)**	Isotope-Labeled Compounds	Others
α-Hydroxy Metoprolol-d₅ (Mixture of Diastereomers) is the deuterium labeled α-Hydroxy Metoprolol Mixture of Diastereomers[1].

HY-W742256

*N-Nitroso nebivolol (mixture* of diastereomers)**	Others	Cancer
N-Nitroso nebivolol (mixture of diastereomers) is a nitrosamine and mutagenic .

HY-12650S

*Mirogabalin-13C2,d1 (Mixture* of Diastereomers)** DS5565-¹³C<sub>2sub>,d<sub>1sub> (Mixture of Diastereomers)	Isotope-Labeled Compounds	Others
Mirogabalin-13C2,d1 (Mixture of Diastereomers) is a C13 and deuterium labeled Mirogabalin. Mirogabalin (DS-5565) is a novel, preferentially selective α2δ-1 ligand characterized by high potency and selectivity to the α2δ-1 subunit of voltage-sensitive calcium channel complexes in the CNS .

HY-132379S

*Hydroxy Pioglitazone-d5 (M-IV) (Mixture* of-diastereomers)**	Isotope-Labeled Compounds	Others
Hydroxy Pioglitazone-d₅ (M-IV) (Mixture of-diastereomers) is the deuterium labeled Hydroxy Pioglitazone (M-IV) (Mixture of-diastereomers)[1].

HY-113026S

*(2RS,4R,8R)-δ-Tocopherol-d4 (Mixture* of Diastereomers)**	Endogenous Metabolite Isotope-Labeled Compounds	Others
(2RS,4R,8R)-δ-Tocopherol-d₄ (Mixture of Diastereomers) is the deuterium labeled (2RS,4R,8R)-δ-Tocopherol (Mixture of Diastereomers)[1].

HY-150857S

*Thymine-α,α,α,6-d4 Glycol (mixture* of diastereomers)-d4**	Isotope-Labeled Compounds	Others
Thymine-α,α,α,6-d₄ Glycol (mixture of diastereomers)-d₄ is the deuterium labeled Thymine-α,α,α,6-d4 Glycol (mixture of diastereomers)[1].

HY-D1249

*Calcein (mixture* of isomers)**	Fluorescent Dye	Others
Calcein mixture of isomers is a calcium-dependent fluorescent molecule. Calcein mixture of isomers can be used to study bone metabolism (in vivo) and to stain depressed areas (in vitro). Calcein mixture of isomers can also be used for fluorometry and EDTA titration of calcium.

HY-RS13999

SUB1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SUB1 Human Pre-designed siRNA Set A contains three designed siRNAs for SUB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SUB1 Human Pre-designed siRNA Set A SUB1 Human Pre-designed siRNA Set A

HY-14620A

*Farnesene (mixture* of isomers)**	Others	Others
Farnesene (mixture of isomers) is a farnesene with mixture of isomers. Farnesene is a herbivore-induced plant volatile (HIPV). Farnesene has an important effect on insect resistance in many plant species .

HY-W763562

*Tridecanol (mixture* of isomers)**	Biochemical Assay Reagents	Others
Tridecanol (mixture of isomers) is a biochemical reagent.

HY-146227

DNA topoisomerase II inhibitor 1	Topoisomerase Apoptosis	Cancer
DNA topoisomerase II inhibitor 1 (compound 8ed) is a potent DNA topoisomerase II inhibitor. DNA topoisomerase II inhibitor 1 shows anti-proliferative activity. DNA topoisomerase II inhibitor 1 induces apoptosis and cell cycle arrest at sub G1 phase .

HY-159669

*Stercobilin hydrochloride (mixture* of isomers)**	HIV Protease	Infection Inflammation/Immunology
Stercobilin hydrochloride (amixture of isomers) is a bile pigment metabolized by gut bacteria, and it's also an HIV protease inhibitor, with a K_i of 4 μM. Stercobilin hydrochloride (a mixture of isomers) can induce pro-inflammatory activity in mouse macrophage RAW264 cells, including the production of TNF-α and IL-1β. Stercobilin hydrochloride (a mixture of isomers) can be used in studies of inflammation and viral infections .

HY-131152

*Leucinostatin (mixture* of A&B)**	Antibiotic	Infection Inflammation/Immunology
Leucinostatin (mixture of A&B), the major components of an atypical nonapeptide complex produced by Paecilomyces lilacinus, are antibiotics .

HY-W250128

*Dodecenylsuccinic anhydride (mixture* of isomers)** DDSA (Mixture of isomers)	Biochemical Assay Reagents	Others
2-Dodecen-1-Ylsuccinic Anhydride is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Dodecenylsuccinic anhydride (mixture of isomers) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-N6013

*Aloin(mixture* of A&B)**	MMP Bacterial Fungal	Infection Inflammation/Immunology Cancer
Aloin (mixture of A&B) is anthraquinone derivative isolated from Aloe vera. Aloin (mixture of A&B) has diverse biological activities such as anti-inflammatory, immunity, antidiabetic, antioxidant, antibacterial, antifungal, and antitumor activities. Aloin (mixture of A&B) also an effective inhibitor of stimulated granulocyte matrix metalloproteinases (MMPs) .

HY-W018772R

*D-Ribose(mixture* of isomers) (Standard)**	Endogenous Metabolite	Inflammation/Immunology Cancer
D-Ribose(mixture of isomers) (Standard) is the analytical standard of D-Ribose(mixture of isomers). This product is intended for research and analytical applications. D-Ribose(mixture of isomers) is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose(mixture of isomers) is active in protein glycation, induces NF-κB inflammation in a RAGE-dependent manner .

HY-132637S

*Chlorfenvinphos-d10(Mixture* of cis-trans isomers)**	Isotope-Labeled Compounds	Others
Chlorfenvinphos-d₁₀(Mixture of cis-trans isomers) is the deuterium labeled Chlorfenvinphos (Mixture of cis-trans isomers)[1].

HY-W018772

*D-Ribose(mixture* of isomers)** 3 Publications Verification	Endogenous Metabolite	Inflammation/Immunology Cancer
D-Ribose(mixture of isomers) is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose(mixture of isomers) is active in protein glycation, induces NF-κB inflammation in a RAGE-dependent manner .

HY-W776824

*2-Phthalimidolactosamine,heptaacetate (mixture* of isomers)**	Biochemical Assay Reagents	Others
2-Phthalimidolactosamine,heptaacetate (mixture of isomers) is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .

HY-W018772S15

*D-Ribose(mixture* of isomers)-13C5**	Endogenous Metabolite	Inflammation/Immunology
D-Ribose(mixture of isomers)- ¹³C₅ isomers)- ¹³C₅ is the ¹³C labeled D-Ribose(mixture of isomers)[1]. D-Ribose(mixture of isomers) is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose(mixture of isomers) is active in protein glycation, induces NF-κB inflammation in a RAGE-dependent manner[1].

HY-10844S1

Pretomanid-d5 PA-824-d<sub>5sub>; (S)-PA 824-d<sub>5sub>	Antibiotic Bacterial Isotope-Labeled Compounds	Infection Cancer
Pretomanid-d₅ is deuterated labeled Pretomanid (HY-10844). Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 μg/mL.

HY-107327S

Carazolol-d7 (±)-Carazolol-d<sub>7sub>; DL-Carazolol-d<sub>7sub>; Suacron-d<sub>7sub>	Adrenergic Receptor	Others
Carazolol-d₇ is the deuterium labeled Carazolol[1].

HY-N0006S

Demethoxycurcumin-d7 Curcumin II-d<sub>7sub>; Desmethoxycurcumin-d<sub>7sub>; Monodemethoxycurcumin-d<sub>7sub>	Isotope-Labeled Compounds Apoptosis Autophagy Bacterial	Inflammation/Immunology Cancer
Demethoxycurcumin-d₇ is the deuterium labeled Demethoxycurcumin. Demethoxycurcumin(Curcumin II), a major active curcuminoid, possess anti-inflammatory properties; also exert cytotoxic effects in human cancer cells via induction of apoptosis.

HY-66005S2

Acetaminophen-d7 Paracetamol-d<sub>7sub>; 4-Acetamidophenol-d<sub>7sub>; 4'-Hydroxyacetanilide-d<sub>7sub>	COX Endogenous Metabolite Histone Acetyltransferase	Inflammation/Immunology
Acetaminophen-d₇ is the deuterium labeled Acetaminophen. Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM; is a widely used antipyretic and analgesic agent. Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor.

HY-B0389S6

D-Glucose-d7 Glucose-d<sub>7sub>; D-(+)-Glucose-d<sub>7sub>; Dextrose-d<sub>7sub>	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
D-Glucose-d₇7 is the deuterium labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].

HY-107352S

Fosfenopril-d7 Fosinoprilat-d<sub>7sub>; Fosinoprilic acid-d<sub>7sub>; SQ 27519-d<sub>7sub>	Angiotensin-converting Enzyme (ACE) Interleukin Related NF-κB TNF Receptor Toll-like Receptor (TLR) Isotope-Labeled Compounds	Others
Fosfenopril-d₇ is deuterium labeled Fosfenopril.

HY-D0711S2

Indocyanine green-d7 Foxgreen-d<sub>7sub>; IC Green-d<sub>7sub>; Cardiogreen-d<sub>7sub>	Isotope-Labeled Compounds Fluorescent Dye	Others
Indocyanine green-d7 (Foxgreen-d7) is the deuterium labeled Indocyanine green (HY-D0711). Indocyanine green is a low toxicic fluorescent agent that has been widely used in medical diagnostics, such as determining cardiac output, hepatic function, and liver blood flow, and for ophthalmic angiography .

HY-12057S1

Vemurafenib-d7 PLX4032-d<sub>7sub>; RG7204-d<sub>7sub>; RO5185426-d<sub>7sub>	Isotope-Labeled Compounds Raf Autophagy	Cancer
Vemurafenib-d₇ is deuterium labeled Vemurafenib. Vemurafenib (PLX4032) is a first-in-class, selective, potent inhibitor of B-RAF kinase, with IC50s of 31 and 48 nM for RAFV600E and c-RAF-1, respectively[1][4]. Vemurafenib induces cell autophagy[5].

HY-Y0376S

DMPA-d7 Bis-MPA-d<sub>7sub>; Dimethylolpropionic acid-d<sub>7sub>; Nikkamer PA-d<sub>7sub>	Isotope-Labeled Compounds	Others
DMPA-d₇ is the deuterium labeled DMPA[1].

HY-10792A

*Eplivanserin (mixture)* SR-46349 (Mixture)	Serotonin Transporter 5-HT Receptor	Neurological Disease
Eplivanserin mixture (SR-46349 mixture) is a selective serotonin reuptake inhibitor and a 5-HT_2A receptor antagonist, extracted from patent WO 2005/002578 A1 .

HY-Y1309S1

1-Naphthol-d7 Furro ER-d<sub>7sub>; NSC 9586-d<sub>7sub>; Nako TRB-d<sub>7sub>	Isotope-Labeled Compounds	Others
1-Naphthol-d7 is the deuterium labeled Naphthol .

HY-113679

Ceramides Mixture 1 Publications Verification	Telomerase	Metabolic Disease Endocrinology
Ceramides Mixture is an endogenous ceramide and consists of hydroxy and non-hydroxy fatty acid-containing ceramides. Ceramides Mixture is a main lipid component of the permeability barrier in epidermis. Ceramides Mixture is involved in the regulation of growth inhibition, cell cycle arrest, and modulation of telomerase activity .

HY-135328S

Norverapamil-d7 (±)-Norverapamil-d<sub>7sub>; D591-d<sub>7sub>	Calcium Channel P-glycoprotein Drug Metabolite	Cardiovascular Disease
Norverapamil-d₇ is a deuterium labeled Norverapamil ((±)-Norverapamil). Norverapamil, an N-demethylated metabolite of Verapamil, is a L-type calcium channel blocker and a P-glycoprotein (P-gp) function inhibitor[1][2].

HY-17025S

Rifabutin-d7 Ansamycin-d<sub>7sub>; LM-427-d<sub>7sub>	Isotope-Labeled Compounds Bacterial Antibiotic	Infection
Rifabutin-d₇ is the deuterium labeled Rifabutin. Rifabutin (Ansamycin) is a semisynthetic ansamycin antibiotic with potent antimycobacterial properties. Rifabutin inhibits DNA-dependent RNA polymerase.

HY-107855S

DL-Mevalonolactone-d7 (±)-Mevalonolactone-d<sub>7sub>; Mevalolactone-d<sub>7sub>	Endogenous Metabolite	Metabolic Disease
DL-Mevalonolactone-d₇ is the deuterium labeled DL-Mevalonolactone. DL-Mevalonolactone ((±)-Mevalonolactone) is the δ-lactone form of mevalonic acid, a precursor in the mevalonate pathway. DL-Mevalonolactone (Mevalonolactone) decreases mitochondrial membrane potential (∆Ψm), NAD(P)H content and the capacity to retain Ca2+ in the brain, besides inducing mitochondrial swelling[1][2].

HY-41700S3

D-Alanine-d7 (R)-Alanine-d<sub>7sub>; Ba 2776-d<sub>7sub>; D-α-Alanine-d<sub>7sub>	Endogenous Metabolite	Neurological Disease
D-Alanine-d₇ is the deuterium labeled D-Alanine. D-Alanine is a weak GlyR (inhibitory glycine receptor) and PMBA agonist, with an EC50 of 9 mM for GlyR.

HY-30237S

(R)-Roscovitine-d7 Seliciclib-d<sub>7sub>; CYC202-d<sub>7sub>	CDK Isotope-Labeled Compounds	Cancer
(R)-Roscovitine-d₇ (Seliciclib-d₇; CYC202-d₇) is deuterium-labeled (R)-Roscovitine (HY-30237) .

HY-B0679S

Lubiprostone-d7 RU-0211-d<sub>7sub>; SPI-0211-d<sub>7sub>	Chloride Channel	Metabolic Disease
Lubiprostone-d₇ (RU-0211-d7) is the deuterium labeled Lubiprostone. Lubiprostone (RU0211) is a gastrointestinal agent used for the treatment of idiopathic chronic constipation[1][2].

HY-50898S1

Lapatinib-d7 dihydrochloride GW572016-dd<sub>7sub> dihydrochloride; GW2016-dd<sub>7sub> dihydrochloride	Isotope-Labeled Compounds EGFR Autophagy Ferroptosis	Cancer
Lapatinib-d₇ (dihydrochloride) is the deuterium labeled Lapatinib dihydrochloride. Lapatinib (GW572016) dihydrochloride is a potent inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively[1].

HY-12296S

Navtemadlin-d7 AMG 232-d<sub>7sub>; KRT-232-d<sub>7sub>	Isotope-Labeled Compounds MDM-2/p53 E1/E2/E3 Enzyme	Cancer
Navtemadlin-d₇ is the deuterium labeled Navtemadlin. Navtemadlin (AMG 232) is a potent, selective and orally available inhibitor of p53-MDM2 interaction, with an IC50 of 0.6 nM. Navtemadlin binds to MDM2 with a Kd of 0.045 nM[1][2].

HY-13720AS

Pergolide-d7 mesylate Pergolide methanesulfonate-d<sub>7sub>; LY127809-d<sub>7sub>	Isotope-Labeled Compounds Dopamine Receptor	Neurological Disease
Pergolide-d₇ (mesylate) is the deuterium labeled Pergolide mesylate. Pergolide mesylate (Pergolide methanesulfonate), an Ergoline derivative, is a potent and orally active dopamine D1 and D2 receptors agonist. Pergolide mesylate can be used for Parkinson's disease and hyperprolactinaemia research[1][2].

HY-N2334AS

Glycochenodeoxycholic acid-d7 sodium Chenodeoxycholylglycine-d<sub>7sub> (sodium); Sodium glycochenodeoxycholate-d<sub>7sub>	Endogenous Metabolite Apoptosis	Cancer
Glycochenodeoxycholic acid-d₇ (sodium) is the deuterium labeled Glycochenodeoxycholic acid (sodium salt). Glycochenodeoxycholic acid sodium salt (Chenodeoxycholylglycine sodium salt) is a bile acid formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. Glycochenodeoxycholic acid sodium salt (Chenodeoxycholylglycine sodium salt) induces hepatocyte apoptosis[1][2].

HY-12785S1

Albendazole sulfoxide-d7 Ricobendazole-d<sub>7sub>; Albendazole oxide-d<sub>7sub>	Isotope-Labeled Compounds Parasite	Infection
Albendazole sulfoxide-d₇ is the deuterium labeled Albendazole sulfoxide. Albendazole sulfoxide (Ricobendazole), the main active metabolite of Albendazole, exhibits anti-parasite effect against Echinococcus multilocularis Metacestodes[1].

HY-14268S1

Febuxostat-d7 TEI 6720-d<sub>7sub>; TMX 67-d<sub>7sub>	Isotope-Labeled Compounds Xanthine Oxidase	Metabolic Disease Cancer
Febuxostat-d₇ is deuterium labeled Febuxostat. Febuxostat (TEI 6720) is selective xanthine oxidase inhibitor with a Ki of 0.6 nM[1].

HY-B1674S4

(±)-Leucine-d7 DL-Leucine-d<sub>7sub>; (RS)-Leucine-d<sub>7sub>	Isotope-Labeled Compounds Endogenous Metabolite Bacterial	Metabolic Disease
(±)-Leucine-d₇ is the deuterium labeled (±)-Leucine. (±)-Leucine (DL-Leucine), an isomer of Leucine, chemosterilant and dietary additive. (±)-Leucine inhibits growth of Escherichia coli HfrH by 92.08%[1].

HY-N0650S11

L-Serine-d7 (-)-Serine-d<sub>7sub>; (S)-Serine-d<sub>7sub>	Isotope-Labeled Compounds Endogenous Metabolite	Cancer
L-Serine-d₇ is the deuterium labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N6013

*Aloin(mixture* of A&B)**	Infection Liliaceae Classification of Application Fields Ketones, Aldehydes, Acids Source classification Phenols Polyphenols Aloe vera (L.) Burm. f. Plants Inflammation/Immunology Disease Research Fields	MMP Bacterial Fungal
Aloin (mixture of A&B) is anthraquinone derivative isolated from Aloe vera. Aloin (mixture of A&B) has diverse biological activities such as anti-inflammatory, immunity, antidiabetic, antioxidant, antibacterial, antifungal, and antitumor activities. Aloin (mixture of A&B) also an effective inhibitor of stimulated granulocyte matrix metalloproteinases (MMPs) .

HY-W018772

*D-Ribose(mixture* of isomers)** 3 Publications Verification	Structural Classification Microorganisms Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Saccharides Cancer	Endogenous Metabolite
D-Ribose(mixture of isomers) is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose(mixture of isomers) is active in protein glycation, induces NF-κB inflammation in a RAGE-dependent manner .

HY-125833

Alpha-Naphthoflavone 5+ Cited Publications	Flavonoids Flavones Source classification Indigofera heterantha Wall. ex Brand. Plants Compositae Disease Research Fields Cancer	Cytochrome P450 Aryl Hydrocarbon Receptor Apoptosis
Alpha-Naphthoflavone is an orally active flavonoid that is a potent, competitive inhibitor of aromatase< b>aromatase. < b > IC < sub > 50 < / sub > < / b > and < b > K < sub > I < / sub > < / b > value were 0.5 and 0.2 microns. Alpha-Naphthoflavone can inhibit cell proliferation and induce apoptosis .

HY-139637

(±)-Silybin Silibinin (Mixture of Silybin A and Silybin B)	Structural Classification Flavanonols Flavonoids Source classification Cyamopsis tetragonoloba (L.) Taub. Plants Compositae	Others
(±)-Silybin is the racemate of Silybin (HY-N0779A). Silybin induces apoptosis and exhibits hepatoprotective, antioxidant, anti-inflammatory, anti-cancer activity .

HY-W011474

Geranylgeraniol	Structural Classification Natural Products Microorganisms	NF-κB
Geranylgeraniol is an orally acitve vitamin K₂ sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model .

HY-P2274

Argifin	Infection Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields	Parasite
Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms, with IC₅₀s of 0.025 μM, 6.4 μM , 1.1 μM and 4.5 μM for SmChiA (Serratia marcescens chitinaese A), SmChiB, Aspergillus fumigatus chitinase B1 and human chitotriosidase, respectively .

HY-131152

*Leucinostatin (mixture* of A&B)**	Structural Classification Microorganisms Antifungal Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Anticancer Inflammation/Immunology Disease Research Fields Other Antibiotics	Antibiotic
Leucinostatin (mixture of A&B), the major components of an atypical nonapeptide complex produced by Paecilomyces lilacinus, are antibiotics .

HY-W018772R

*D-Ribose(mixture* of isomers) (Standard)**	Structural Classification Microorganisms Source classification Endogenous metabolite Saccharides	Endogenous Metabolite
D-Ribose(mixture of isomers) (Standard) is the analytical standard of D-Ribose(mixture of isomers). This product is intended for research and analytical applications. D-Ribose(mixture of isomers) is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose(mixture of isomers) is active in protein glycation, induces NF-κB inflammation in a RAGE-dependent manner .

HY-N11799

Neochilenin 3-O-Methylquercetin 4′-O-glucoside	Structural Classification Flavonoids Source classification Plants Compositae Other Flavonoids	Others
Neochilenin (3-O-Methylquercetin 4 '-O-glucoside) is a glycoside of 3-O-methylquercetin, which can be isolated from the sub-family Cereoideae (Cactaceae). .

HY-N10192

Aculene D	Infection Microorganisms Classification of Application Fields Terpenoids Sesquiterpenes Source classification Disease Research Fields	Endogenous Metabolite Bacterial
Aculene D, a fungal metabolite, shows quorum sensing (QS) inhibitory activity against Chromobacterium violaceum CV026, and could significantly reduce violacein production in N-hexanoyl-l-homoserine lactone (C6-HSL) induced C. violaceum CV026 cultures at sub-inhibitory concentrations .

HY-W011474R

Geranylgeraniol (Standard)	Structural Classification Natural Products Microorganisms	NF-κB
Geranylgeraniol (Standard) is the analytical standard of Geranylgeraniol. This product is intended for research and analytical applications. Geranylgeraniol is an orally acitve vitamin K2 sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model [4].

HY-N0662

Amentoflavone 5+ Cited Publications Didemethyl-ginkgetin	Structural Classification Flavonoids Classification of Application Fields Source classification Phenols Polyphenols Selaginellaceae Plants Biflavones Selaginella tamariscina (P. Beauv.) Spring Disease Research Fields Cancer	Reactive Oxygen Species Apoptosis Bacterial Fungal RSV GABA Receptor
Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active GABA(A) negative modulator. Amentoflavone also shows anti-inflammatory, antioxidative, anti-viral, anti-tumor, anti-radiation, anti-fungal, antibacterial activity. Amentoflavone induces apoptosis and cell cycle arrest at sub-G1 phase .

HY-P99294

Ganitumab AMG 479; Human Anti-IGF1R Recombinant Antibody	Classification of Application Fields Disease Research Fields Cancer	IGF-1R
Ganitumab (AMG 479) is a recombinant human monoclonal antibody to the human type 1 insulin-like growth factor receptor (IGF1R). Ganitumab recognizes murine IGF1R with sub-nanomolar affinity (K_D=0.22 nM) and inhibits the interaction of murine IGF1R with IGF1 and IGF2. Ganitumab can be used in research of cancer .

HY-N8549A

5-Dihydrocortisone	Structural Classification Classification of Application Fields Cardiacglycosides Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite
5-Dihydrocortisone is a 5-Dihydrocortisone with mixture of isomers. 5β-Dihydrocortisone is a sterol metabolite of cortisone by 5β-reductase (AKR1D1) in liver

HY-N0662R

Amentoflavone (Standard)	Structural Classification Flavonoids Source classification Phenols Polyphenols Selaginellaceae Plants Biflavones Selaginella tamariscina (P. Beauv.) Spring	Reactive Oxygen Species Apoptosis Bacterial Fungal RSV GABA Receptor
Amentoflavone (Standard) is the analytical standard of Amentoflavone. This product is intended for research and analytical applications. Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active GABA(A) negative modulator. Amentoflavone also shows anti-inflammatory, antioxidative, anti-viral, anti-tumor, anti-radiation, anti-fungal, antibacterial activity. Amentoflavone induces apoptosis and cell cycle arrest at sub-G1 phase .

HY-W751835

Baloxavir-d4 25+ Cited Publications Baloxavir acid-d<sub>4sub>; S-033447-d<sub>4sub>	Classification of Application Fields Disease Research Fields Cancer	Isotope-Labeled Compounds
Baloxavir-d₄ (Baloxavir acid-d₄; S-033447-d₄) is the deuterium-labeled Baloxavir (HY-109025A). Baloxavir-d₄ (Baloxavir-d₄ acid), derived from the proagent Baloxavir-d₄ marboxil, is a first-in-class, potent and selective cap-dependent endonuclease (CEN) inhibitor within the polymerase PA subunit of influenza A and B viruses. Baloxavir-d₄ inhibits viral RNA transcription and replication and has potently antiviral activity .

HY-B0504S

Creatinine-d3 3 Publications Verification NSC13123-d<sub>3sub>	Classification of Application Fields Metabolic Disease Disease Research Fields	Endogenous Metabolite
Creatinine-d₃ is a deuterium labeled Creatinine. Creatinine is a break-down product of creatine phosphate in muscle[1].

HY-113434B

5-HETE (±)-5-HETE	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite
5-HETE ((±)-5-HETE), a fatty acid, is a oxidative derivative of Arachidonic acid. 5-HETE is a mixture of 5(S)-HETE and 5(R)-HETE. 5-HETE is a potent aggregating agent that induces the aggregation of neutrophils with an IC₅₀ value of 200 nM .

HY-N7265

Epi-galantamine	Alkaloids other families Source classification Plants	Cholinesterase (ChE)
Epi-galantamine is a diastereomer of Galantamine. Epi-galantamine is an alkaloid isolated from the bulbs and flowers of Caucasian snowdrop (Galanthus woronowii). Epi-galantamine inhibits AChE with an EC₅₀ of 45.7 μM .

HY-N2078

Yamogenin Neodiosgenin	Structural Classification other families Classification of Application Fields Source classification Metabolic Disease Plants Disease Research Fields Steroids	LXR
Yamogenin (Neodiosgenin) is a diastereomer of diosgenin. Yamogenin (Neodiosgenin) antagonizes the activation of the liver X receptor (LXR) in luciferase ligand assay. Yamogenin (Neodiosgenin) inhibits triacylglyceride (TG) accumulation through the suppression of gene expression of fatty acid synthesis in HepG2 hepatocytes .

HY-W794998

Cedarwood terpenes	Structural Classification Other Monoterpenes Cedrus deodara (Roxburgh) G. Don Pinaceae Terpenoids Source classification Plants	Others
Cedarwood terpenes is a natural terpene mixture that can be extracted from cedar wood .

HY-N7084

Methyl dihydrojasmonate	Structural Classification Oleaceae Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Jasminum grandiflorum Plants Disease Research Fields	Others
Methyl dihydrojasmonate is a fragrance ingredient with a jasmine-like odor, used in many fragrance mixtures .

HY-N9761

Murrayanine	Structural Classification Alkaloids Pyrrole Alkaloids Source classification Rutaceae Murraya koenigii (L.) Spreng Plants	Others
Murrayanine is a dimeric pyranoquinoline alkaloid, a mixture of two enantiomers with a predominant configuration on the chiral axis .

HY-N0683A

rel-α-Vitamin E rel-D-α-Tocopherol	Natural Products Monophenols other families Classification of Application Fields Source classification Phenols Plants Inflammation/Immunology Disease Research Fields	Others
rel-α-Vitamin E (rel-D-α-Tocopherol) is a vitamin with antioxidant properties and also a mixture .

HY-B0399A

DL-Carnitine (±)-Carnitin	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Mitochondrial Metabolism
DL-Carnitine is a racemic mixture of L-Carnitine and D-Carnitine, regulates fatty acid transport in mitochondria, elevates serum carnitine fractions.

HY-B2236

DL-Lysine (±)-2,6-Diaminocaproic acid	Classification of Application Fields Source classification Metabolic Disease Amino acids Endogenous metabolite Disease Research Fields	Others
DL-Lysine is a racemic mixture of the D-Lysine and L-Lysine. Lysine is an α-amino acid that is used in the biosynthesis of proteins .

HY-N2078R

Yamogenin (Standard)	Structural Classification other families Source classification Plants Steroids	LXR
Yamogenin (Standard) is the analytical standard of Yamogenin. This product is intended for research and analytical applications. Yamogenin (Neodiosgenin) is a diastereomer of diosgenin. Yamogenin (Neodiosgenin) antagonizes the activation of the liver X receptor (LXR) in luciferase ligand assay. Yamogenin (Neodiosgenin) inhibits triacylglyceride (TG) accumulation through the suppression of gene expression of fatty acid synthesis in HepG2 hepatocytes .

HY-114158A

Pronase E (Activity ≥ 4000 U/mg) 5 Publications Verification Pronase (Activity ≥ 4000 U/mg)	Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Other Diseases Disease Research Fields	Biochemical Assay Reagents
Pronase E (Activity ≥ 4000 U/mg) is a mixture of proteolytic enzymes that is obtained from Streptomyces griseus and could digest protein into individual amino acids .

HY-114158

Pronase E (Activity ≥ 7000 U/g) 15+ Cited Publications Pronase (Activity ≥ 7000 U/g)	Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Other Diseases Disease Research Fields Cancer	Biochemical Assay Reagents
Pronase E (Activity ≥ 7000 U/g) is a mixture of proteolytic enzymes that is obtained from Streptomyces griseus and could digest protein into individual amino acids .

HY-Y0507

DL-Serine 1 Publications Verification	Infection Structural Classification other families Classification of Application Fields Ketones, Aldehydes, Acids Source classification Plants Disease Research Fields	TMV
DL-Serine, a fundamental metabolite, is a mixture of D-Serine and L-Serine. DL-Serine has antiviral activity against the multiplication of tobacco mosaic virus (TMV) .

HY-10448A

Capsaicin (Purity 65%) 15+ Cited Publications	Structural Classification Monophenols Capsicum annuum L. Neurological Disease Classification of Application Fields Source classification Phenols Solanaceae Plants Inflammation/Immunology Disease Research Fields	TRP Channel Autophagy Apoptosis Endogenous Metabolite
Capsaicin (Purity 65%) is a mixture of Capsaicin and Dihydrocapsaicin (Ratio >2:1).Capsaicin (Purity 65%) is an orally active capsaicin receptor (TRPV1) agonist .

HY-120109

13-HODE methyl ester	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite
13-HODE methyl ester, a racemic mixture of 13(R)-HODE methyl ester and 13(S)-HODE methyl ester, is a 15-lipoxygenase metabolite of Linoleic acid .

HY-N2543

Damascenone (E/Z)-Damascenone	Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Rosaceae Plants Inflammation/Immunology Disease Research Fields Rosa rugosa Thunb.	NF-κB Endogenous Metabolite
Damascenone ((E/Z)-Damascenone) is an active compound of?Epipremnum pinnatum with anti-inflammatory activity . Damascenone is a mixture complex of?E-isomer-Damascenone and Z-isomer Damascenone.

HY-N4301

Monensin B	Natural Products Microorganisms Classification of Application Fields Source classification Other Diseases Disease Research Fields	Others
Monensin B is a polyketide produced by Streptomyces cinnamonensis. Fermentations of Streptomyces cinnamonensis produce a mixture of Monensin A and Monensin B in a ratio dependent upon the relative concentrations of ethylmalonyl-CoA and methylmalonyl-CoA .

HY-N10130

Isouvaretin	Infection Flavonoids other families Classification of Application Fields Source classification Phenols Polyphenols Plants Dihydrochalcones Disease Research Fields	Bacterial
A mixture of uvaretin (HY-N10129) and isouvaretin exhibits significant antibacterial activity against B. subtilis (EC₅₀ 8.7 μM) and S. epidermidis (IC₅₀ 7.9 μM).

HY-N7084R

Methyl dihydrojasmonate (Standard)	Structural Classification Oleaceae Ketones, Aldehydes, Acids Source classification Jasminum grandiflorum Plants	Others
Methyl dihydrojasmonate (Standard) is the analytical standard of Methyl dihydrojasmonate. This product is intended for research and analytical applications. Methyl dihydrojasmonate is a fragrance ingredient with a jasmine-like odor, used in many fragrance mixtures .

HY-N5056

DL-Goitrin 1 Publications Verification	Structural Classification Natural Products Cruciferous vegetables Classification of Application Fields Source classification Other Diseases Plants Brassicaceae Disease Research Fields	Influenza Virus
DL-Goitrin, also called (R, S)- report by the spring, consists of the epigoitrin (reported by the R- Spring) and the spring (-S- reported by spring), and the two mutually isomers, and the mixture is the ingredient of cruciferous vegetables .

HY-105790

Piperilate Pipethanate	Cardiovascular Disease Classification of Application Fields Disease Research Fields	Cholinesterase (ChE)
Piperilate (Pipethanate) is one of the mixtures of hetrazepine derivative PAF antagonists with anticholinergics, can be used for bronchial asthma research. Piperilate also causes hypotension and rescues mice poisoned by the organophosphates .

HY-116663

(±)20-HDHA (±)20-HDoHE	Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Endogenous Metabolite
(±)20-HDHA ((±)20-HDoHE) is a racemic mixture and is an autoxidation product of Docosahexaenoic acid (DHA). (±)20-HDHA is also formed by peroxidation process in human platelets and rat brain homogenate .

HY-N12823

Caprazene	Structural Classification Microorganisms Antibiotics Source classification	Bacterial
Caprazene is an antimycobacterial compound and precursor molecule for semi-synthetic antibacterial antibiotics, used for studies on tuberculosis and Mycobacterium avium complex infections, which can be isolated from the acid-treated caprazamycin (CPZ) A-G mixture .

HY-P99540

Tuvonralimab PSB-205; QL1706 (iparomlimab/tuvonralimab); PBS105	Classification of Application Fields Disease Research Fields Cancer	PD-1/PD-L1 CTLA-4
Tuvonralimab (PSB-205; QL1706) is a dual immune checkpoint blockade containing a mixture of anti-PD-1 IgG4 and anti-CTLA-4 IgG1 antibodies, Iparomlimab and Tuvonralimab .

HY-N2059

Santalol	Structural Classification other families Classification of Application Fields Santalum album Linn. Terpenoids Sesquiterpenes Source classification Plants Disease Research Fields Santalaceae Cancer	Others
Santalol is a mixture of α and β-isomer santalol. α-santalol is isolated from sandalwood oil. α-santalol is a promising anti-cancer agent against cancers such as oral, breast, prostate and skin cancer .

HY-N8425

Octacosanoic acid Montanic acid	Structural Classification Croton caudatus Geisel. Croton. Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Euphorbiaceae Plants Disease Research Fields	Endogenous Metabolite
Octacosanoic acid is a very long-chain saturated fatty acid. It is the major component of D-003, a mixture of very long-chain aliphatic acids purified from sugar cane wax that has antiplatelet and cholesterol-lowering activities in animal models .

HY-B2134

Casanthranol	Structural Classification Natural Products other families Classification of Application Fields Source classification Metabolic Disease Plants Disease Research Fields	Others
Casanthranol is a concentrated mixture of anthranol glycosides from cascara sagrada (dried bark of Rhamnus p.) and used as a laxative in constipation and various medical conditions, stimulant laxative Casanthranol encourages bowel movements by acting on the intestinal wall to increase muscle contractions .

HY-N2543R

Damascenone (Standard)	Structural Classification Natural Products Microorganisms Source classification Rosaceae Plants Rosa rugosa Thunb.	NF-κB Endogenous Metabolite
Damascenone (Standard) is the analytical standard of Damascenone. This product is intended for research and analytical applications. Damascenone ((E/Z)-Damascenone) is an active compound of Epipremnum pinnatum with anti-inflammatory activity . Damascenone is a mixture complex of E-isomer-Damascenone and Z-isomer Damascenone.

HY-101399

γ-Glu-Phe γ-Glutamylphenylalanine	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
γ-Glu-Phe (γ-Glutamylphenylalanine) is synthesized by Bacillus amyloliquefaciens (GBA) and Aspergillus oryzae (GAO). γ-Glu-Phe or the post-enzymatic reaction mixture enhances the umami intensity of commercial soy sauce and model chicken broth .

HY-N7497

Protoescigenin	Triterpenes Structural Classification other families Classification of Application Fields Terpenoids Source classification Other Diseases Plants Disease Research Fields	Others
Protoescigenin is the main aglycone of horse chestnut saponin mixture known as escin. Protoescigenin is selected as substrate for exploratory chemistry towards selective protection, followed by propargyl ether formation and subsequent condensation with azido-monosaccharides, to obtain novel triazole linked conjugates of the triterpene .

HY-N6706

Enniatin complex	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Source classification Antibacterial Disease Research Anticancer Disease Research Fields Other Antibiotics	Bacterial Acyltransferase Apoptosis
Enniatin complex is a mixture of cyclohexadepsipeptides isolated largely from Fusarium species of fungi, and has ionophoric, antibiotic, and in vitro hypolipidaemic properties. Enniatin complex inhibits enzymes like acyl-CoA: cholesterol acyl transferase and induces apoptosis in several cancer lines .

HY-W355141

Isopulegol	Structural Classification Natural Products Classification of Application Fields Source classification Essence, Fragrance Myrtaceae Cosmetic Research Plants Disease Research Fields Cancer Eucalyptus citriodora Hook. f.	Others
Isopulegol is one of the main components of ECO (Eucalyptus citriodora oil). ECO has antibacterial activity .

HY-116757

(±)-α-CMBHC	Cardiovascular Disease Structural Classification Monophenols Classification of Application Fields Ketones, Aldehydes, Acids Source classification Phenols Endogenous metabolite Disease Research Fields	Endogenous Metabolite
(±)-α-CMBHC is a metabolite of α-Tocopherol .

Cat. No.	Product Name	Chemical Structure

HY-132382S

β-Sitosterol-d7 (mixture of diasteromers)
β-Sitosterol-d₇ (Mixture of Diastereomers) is the deuterium labeled β-Sitosterol (mixture of diasteromers)[1].

HY-132676S

*Ramiprilat-d5 (Mixture* of Diastereomers)**
Ramiprilat-d₅ (Mixture of Diastereomers) is the deuterium labeled Ramiprilat (Mixture of Diastereomers)[1].

HY-W653769

*Deltamethrin-d5 (Mixture* of Diastereomers)**
Deltamethrin-d5 (Mixture of Diastereomers) is the deuterium labeled Deltamethrin (Mixture of Diastereomers) .

HY-132706S

*N-Deformyl Formoterol-d6 Fumarate (Mixture* of Diastereomers)**
N-Deformyl Formoterol-d₆ Fumarate (Mixture of Diastereomers) is the deuterium labeled N-Deformyl Formoterol Fumarate (Mixture of Diastereomers)[1].

HY-134670S

*α-Hydroxy Metoprolol-d5 (Mixture* of Diastereomers)**
α-Hydroxy Metoprolol-d₅ (Mixture of Diastereomers) is the deuterium labeled α-Hydroxy Metoprolol Mixture of Diastereomers[1].

HY-12650S

*Mirogabalin-13C2,d1 (Mixture* of Diastereomers)**
Mirogabalin-13C2,d1 (Mixture of Diastereomers) is a C13 and deuterium labeled Mirogabalin. Mirogabalin (DS-5565) is a novel, preferentially selective α2δ-1 ligand characterized by high potency and selectivity to the α2δ-1 subunit of voltage-sensitive calcium channel complexes in the CNS .

HY-132379S

*Hydroxy Pioglitazone-d5 (M-IV) (Mixture* of-diastereomers)**
Hydroxy Pioglitazone-d₅ (M-IV) (Mixture of-diastereomers) is the deuterium labeled Hydroxy Pioglitazone (M-IV) (Mixture of-diastereomers)[1].

HY-113026S

*(2RS,4R,8R)-δ-Tocopherol-d4 (Mixture* of Diastereomers)**
(2RS,4R,8R)-δ-Tocopherol-d₄ (Mixture of Diastereomers) is the deuterium labeled (2RS,4R,8R)-δ-Tocopherol (Mixture of Diastereomers)[1].

HY-150857S

*Thymine-α,α,α,6-d4 Glycol (mixture* of diastereomers)-d4**
Thymine-α,α,α,6-d₄ Glycol (mixture of diastereomers)-d₄ is the deuterium labeled Thymine-α,α,α,6-d4 Glycol (mixture of diastereomers)[1].

HY-132485S

*N-Methyl Pantoprazole-d3 (Mixture* of 1 and 3 isomers)**
N-Methyl Pantoprazole-d3 (Mixture of 1 and 3 isomers) is the deuterium labeled N-Methyl Pantoprazole (Mixture of 1 and 3 isomers) .

HY-132637S

*Chlorfenvinphos-d10(Mixture* of cis-trans isomers)**
Chlorfenvinphos-d₁₀(Mixture of cis-trans isomers) is the deuterium labeled Chlorfenvinphos (Mixture of cis-trans isomers)[1].

HY-W018772S15

D-Ribose(mixture of isomers)-13C5

D-Ribose(mixture of isomers)- ¹³C₅ isomers)- ¹³C₅ is the ¹³C labeled D-Ribose(mixture of isomers)[1]. D-Ribose(mixture of isomers) is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose(mixture of isomers) is active in protein glycation, induces NF-κB inflammation in a RAGE-dependent manner[1].

HY-10844S1

Pretomanid-d5
Pretomanid-d₅ is deuterated labeled Pretomanid (HY-10844). Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 μg/mL.

HY-107327S

Carazolol-d7
Carazolol-d₇ is the deuterium labeled Carazolol[1].

HY-N0006S

Demethoxycurcumin-d7
Demethoxycurcumin-d₇ is the deuterium labeled Demethoxycurcumin. Demethoxycurcumin(Curcumin II), a major active curcuminoid, possess anti-inflammatory properties; also exert cytotoxic effects in human cancer cells via induction of apoptosis.

HY-66005S2

Acetaminophen-d7
Acetaminophen-d₇ is the deuterium labeled Acetaminophen. Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM; is a widely used antipyretic and analgesic agent. Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor.

HY-B0389S6

D-Glucose-d7
D-Glucose-d₇7 is the deuterium labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].

HY-107352S

Fosfenopril-d7
Fosfenopril-d₇ is deuterium labeled Fosfenopril.

HY-D0711S2

Indocyanine green-d7
Indocyanine green-d7 (Foxgreen-d7) is the deuterium labeled Indocyanine green (HY-D0711). Indocyanine green is a low toxicic fluorescent agent that has been widely used in medical diagnostics, such as determining cardiac output, hepatic function, and liver blood flow, and for ophthalmic angiography .

HY-12057S1

Vemurafenib-d7
Vemurafenib-d₇ is deuterium labeled Vemurafenib. Vemurafenib (PLX4032) is a first-in-class, selective, potent inhibitor of B-RAF kinase, with IC50s of 31 and 48 nM for RAFV600E and c-RAF-1, respectively[1][4]. Vemurafenib induces cell autophagy[5].

HY-Y0376S

DMPA-d7
DMPA-d₇ is the deuterium labeled DMPA[1].

HY-Y1309S1

1-Naphthol-d7
1-Naphthol-d7 is the deuterium labeled Naphthol .

HY-135328S

Norverapamil-d7
Norverapamil-d₇ is a deuterium labeled Norverapamil ((±)-Norverapamil). Norverapamil, an N-demethylated metabolite of Verapamil, is a L-type calcium channel blocker and a P-glycoprotein (P-gp) function inhibitor[1][2].

HY-17025S

Rifabutin-d7
Rifabutin-d₇ is the deuterium labeled Rifabutin. Rifabutin (Ansamycin) is a semisynthetic ansamycin antibiotic with potent antimycobacterial properties. Rifabutin inhibits DNA-dependent RNA polymerase.

HY-107855S

DL-Mevalonolactone-d7
DL-Mevalonolactone-d₇ is the deuterium labeled DL-Mevalonolactone. DL-Mevalonolactone ((±)-Mevalonolactone) is the δ-lactone form of mevalonic acid, a precursor in the mevalonate pathway. DL-Mevalonolactone (Mevalonolactone) decreases mitochondrial membrane potential (∆Ψm), NAD(P)H content and the capacity to retain Ca2+ in the brain, besides inducing mitochondrial swelling[1][2].

HY-41700S3

D-Alanine-d7
D-Alanine-d₇ is the deuterium labeled D-Alanine. D-Alanine is a weak GlyR (inhibitory glycine receptor) and PMBA agonist, with an EC50 of 9 mM for GlyR.

HY-30237S

(R)-Roscovitine-d7
(R)-Roscovitine-d₇ (Seliciclib-d₇; CYC202-d₇) is deuterium-labeled (R)-Roscovitine (HY-30237) .

HY-B0679S

Lubiprostone-d7
Lubiprostone-d₇ (RU-0211-d7) is the deuterium labeled Lubiprostone. Lubiprostone (RU0211) is a gastrointestinal agent used for the treatment of idiopathic chronic constipation[1][2].

HY-50898S1

Lapatinib-d7 dihydrochloride
Lapatinib-d₇ (dihydrochloride) is the deuterium labeled Lapatinib dihydrochloride. Lapatinib (GW572016) dihydrochloride is a potent inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively[1].

HY-12296S

Navtemadlin-d7
Navtemadlin-d₇ is the deuterium labeled Navtemadlin. Navtemadlin (AMG 232) is a potent, selective and orally available inhibitor of p53-MDM2 interaction, with an IC50 of 0.6 nM. Navtemadlin binds to MDM2 with a Kd of 0.045 nM[1][2].

HY-13720AS

Pergolide-d7 mesylate
Pergolide-d₇ (mesylate) is the deuterium labeled Pergolide mesylate. Pergolide mesylate (Pergolide methanesulfonate), an Ergoline derivative, is a potent and orally active dopamine D1 and D2 receptors agonist. Pergolide mesylate can be used for Parkinson's disease and hyperprolactinaemia research[1][2].

HY-N2334AS

Glycochenodeoxycholic acid-d7 sodium

Glycochenodeoxycholic acid-d₇ (sodium) is the deuterium labeled Glycochenodeoxycholic acid (sodium salt). Glycochenodeoxycholic acid sodium salt (Chenodeoxycholylglycine sodium salt) is a bile acid formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. Glycochenodeoxycholic acid sodium salt (Chenodeoxycholylglycine sodium salt) induces hepatocyte apoptosis[1][2].

HY-12785S1

Albendazole sulfoxide-d7
Albendazole sulfoxide-d₇ is the deuterium labeled Albendazole sulfoxide. Albendazole sulfoxide (Ricobendazole), the main active metabolite of Albendazole, exhibits anti-parasite effect against Echinococcus multilocularis Metacestodes[1].

HY-14268S1

Febuxostat-d7
Febuxostat-d₇ is deuterium labeled Febuxostat. Febuxostat (TEI 6720) is selective xanthine oxidase inhibitor with a Ki of 0.6 nM[1].

HY-B1674S4

(±)-Leucine-d7
(±)-Leucine-d₇ is the deuterium labeled (±)-Leucine. (±)-Leucine (DL-Leucine), an isomer of Leucine, chemosterilant and dietary additive. (±)-Leucine inhibits growth of Escherichia coli HfrH by 92.08%[1].

HY-N0650S11

L-Serine-d7
L-Serine-d₇ is the deuterium labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-N7745S

Glucosylsphingosine-d7
Glucosylsphingosine-d₇ is deuterium labeled Glucosylsphingosine.

HY-135853S

Molnupiravir-d7

Molnupiravir-d₇ is the deuterium labeled Molnupiravir. Molnupiravir (EIDD-2801) is an orally bioavailable prodrug of the ribonucleoside analog EIDD-1931. Molnupiravir has broad spectrum antiviral activity against influenza virus and multiple coronaviruses, such as SARS-CoV-2, MERS-CoV, SARS-CoV. Molnupiravir has the potential for the research of COVID-19, and seasonal and pandemic influenza[1][2].

HY-14275S1

Verapamil-d7
Verapamil-d₇ is the deuterium labeled Verapamil (HY-14275). Verapamil ((±)-Verapamil) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor. Verapamil also inhibits CYP3A4. Verapamil has the potential for high blood pressure, heart arrhythmias and angina research .

HY-B0202S3

Irbesartan-d7
Irbesartan-d₇ is deuterated labeled Irbesartan (HY-B0202). Irbesartan (SR-47436) is an orally active Ang II type 1 (AT1) receptor blocker (ARB). Irbesartan can relax the blood vessels, low blood pressure and increase the supply of blood and oxygen to the heart. Irbesartan can be used for the research of high blood pressure, heart failure, and diabetic kidney disease .

HY-B0202AS

Irbesartan-d7 hydrochloride

Irbesartan-d₇ hydrochloride is deuterated labeled Irbesartan hydrochloride (HY-B0202A). Irbesartan (SR-47436) hydrochloride is an orally active Ang II type 1 (AT1) receptor blocker (ARB). Irbesartan hydrochloride can relax the blood vessels, low blood pressure and increase the supply of blood and oxygen to the heart. Irbesartan hydrochloride can be used for the research of high blood pressure, heart failure, and diabetic kidney disease .

HY-B0161AS1

Duloxetine-d7 hydrochloride
Duloxetine-d7 hydrochloride ((S)-Duloxetine-d7 hydrochloride) is the deuterium labeled Duloxetine hydrochloride (HY-B0161A). Duloxetine hydrochloride ((S)-Duloxetine hydrochloride) is a serotonin-norepinephrine reuptake inhibitor (SNRI) with a K_i of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD) .

HY-101047S

D-erythro-Sphingosine-d7
D-erythro-Sphingosine-d₇ is the deuterium labeled D-erythro-Sphingosine. D-erythro-Sphingosine (Erythrosphingosine) is a very potent activator of p32-kinase with an EC50 of 8 μM, and inhibits protein kinase C (PKC). D-erythro-Sphingosine (Erythrosphingosine) is also a PP2A activator[1][2][3][4].

HY-B0763S2

Ibudilast-d7-1

Ibudilast-d₇-1 is the deuterium labeled Ibudilast[1]. Ibudilast (KC-404;AV-411;MN-166) is a cyclic AMP phosphodiesterase (PDE) inhibitor. Ibudilast has platelet anti-aggregatory effects. Ibudilast can be used for the research of asthma for its inhibitory effects on tracheal smooth muscle contractility. Ibudilast may be a useful neuroprotective and anti-dementia agent counteracting neurotoxicity in activated microglia[2].

HY-Y1772S

1-Iodo-4-methylbenzene-d7
1-Iodo-4-methylbenzene-d₇ is the deuterium labeled 1-Iodo-4-methylbenzene[1].

HY-14291S1

Vildagliptin-d7
Vildagliptin-d₇ is deuterium labeled Vildagliptin. Vildagliptin (LAF237) is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC50 of 3.5 nM in human Caco-2 cells. Vildagliptin possesses excellent oral bioavailability and potent antihyperglycemic activity[1].

HY-B1178S2

(Rac)-Cotinine-d7
(Rac)-Cotinine-d₇ is deuterium labeled Cotinine.

HY-N2026S

Propylparaben-d7

Propylparaben-d₇ (Propyl parahydroxybenzoate-d₇)is the deuterium labeledPropylparaben(HY-N2026) . Propylparaben (Propyl parahydroxybenzoate) is an antimicrobial preservative which can be produced naturally by plants and bacteria. Propylparaben is prevalently used in cosmetics, pharmaceuticals, and foods. Propylparaben disrupts antral follicle growth and steroidogenic function by altering the cell-cycle, apoptosis, and steroidogenesis pathways. Propylparaben also decreases sperm number and motile activity in rats .

HY-112499S

Menaquinone-7-d7

Menaquinone-7-d₇ is the deuterium labeled Menaquinone-7. Menaquinone-7 (Vitamin K2-7), belongs to a class of K2-vitamin homologs, is originally discovered as the anti-hemorrhagic factors[1]. Menaquinone-7 (Vitamin K2-7) is identified as the most bioactive cofactor for the carboxylation reaction of Gla-proteins [2]. Supplementation with Menaquinone-7 (Vitamin K2-7) is a pharmacological option for activating matrix Gla protein and intervening in the progression of calcific aortic valve stenosis (CAVS)[3].

HY-41463S

4-(Butylamino)benzoic acid-d7
4-(Butylamino)benzoic acid-d₇ is the deuterium labeled 4-(Butylamino)benzoic acid[1].

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