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CRBN<sup>I391V</sup> mice

" in MedChemExpress (MCE) Product Catalog:

2995

Inhibitors & Agonists

1

Screening Libraries

17

Fluorescent Dye

21

Biochemical Assay Reagents

164

Peptides

45

Inhibitory Antibodies

317

Natural
Products

9

Recombinant Proteins

840

Isotope-Labeled Compounds

2

Antibodies

34

Click Chemistry

26

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N6746
    Citrinin

    NSC 186

    		 Bacterial Fungal Endogenous Metabolite Apoptosis Infection Neurological Disease Cancer
    Citrinin (NSC 186) is a mycotoxin that causes food contamination and has different toxic effects. Citrinin shows significant antitumor effects in a mouse model of breast cancer induced by DMBA (HY-W011845). Citrinin has various regulatory effects on mouse immune system, including regulating the number of immune cells, inducing apoptosis and autophagy of immune cells, altering toll-like receptor expression and cytokine production. In addition, Citrinin has antibacterial and neuroprotective activities [1]sup [2]sup [3]sup [4]
    Citrinin
  • HY-15306S
    Eltrombopag-13C4
    1 Publications Verification

    SB-497115-<sup>13sup>C4

    		 Thrombopoietin Receptor Bacterial Apoptosis Infection Cardiovascular Disease Cancer
    Eltrombopag- 13C4 (SB-497115- 13C4) is 13 sup>C-labeled Z-Eltrombopag. Z-Eltrombopag is an orally active thrombopoietin-receptor non-peptide agonist with platelet-stimulating activity for the study of chronic immune thrombocytopenia. Eltrombopag also has strong inhibitory effects on multidrug-resistant Staphylococcus aureus (Staphylococcus aureus) and can induce apoptosis (apoptosis) in liver cancer cells .
    Eltrombopag-13C4
  • HY-126906
    Milbemycin A4

    		Antibiotic P-glycoprotein Cancer
    Milbemycin A4 inhibits P-glycoprotein activity, and reverses multidrug resistance of tumor cells. Milbemycins are a family of macrolide antibiotics with insecticidal and acaricidal activity [1]sup>[2].
    Milbemycin A4
  • HY-W011509
    CyPPA

    		Potassium Channel Neurological Disease
    CyPPA is a positive modulator of hSK3 and hSK2, with EC50 values of 14 μM and 5.6 μM, repectively. CyPPA is inactive on both hSK1 and hIK channels [1]sup .
    CyPPA
  • HY-W342590
    CRBN ligand-9

    		Ligands for E3 Ligase Cancer
    CRBN ligand-9 (Compound 4d) is a CRBN ligand (Ki: 8.9 μM). CRBN ligand-9 can be used for synthesis of PROTACs .
    CRBN ligand-9
  • HY-N12231
    Carbazomycin B

    		Antibiotic Bacterial Lipoxygenase Infection Cancer
    Carbazomycin B is a bacterial metabolite and can be isolated from Streptomyces. Carbazomycin B is an antifungal and antibacterial agent. Carbazomycin B inhibits 5-lipoxygenase (5-LO) activity in extract from RBL-1 cell with the IC50 Of 1.5 µM [1]sup>[2]sup>[3]sup>[4].
    Carbazomycin B
  • HY-108166
    Hydroxystilbamidine

    		Fluorescent Dye Inflammation/Immunology
    Hydroxystilbamidine, a dye capable of binding to both DNA and RNA, is a powerful inhibitor of cellular ribonucleases. Hydroxystilbamidine is a retrograde fluorescent tracer and a histochemical stain [1]sup .
    Hydroxystilbamidine
  • HY-145128
    GR103545

    		Opioid Receptor Neurological Disease
    GR103545 is a potent and selective agonist of the κ-opioid receptor (κ-OR). 11GR103545 is a radiotracer for imaging κ-OR in vivo [1]sup .
    GR103545
  • HY-N11122
    7-[α-L-Arabinopyranosyl-(1→6)-β-D-glucopyranosyloxy]cuminol

    		Others Others
    7-[α-L-Arabinopyranosyl-(1→6)-β-D-glucopyranosyloxy]cuminol is a cuminol glycoside. 7-[α-L-Arabinopyranosyl-(1→6)-β-D-glucopyranosyloxy]cuminol can be isolated from Rhodiola rosea sup>[1].
    7-[α-L-Arabinopyranosyl-(1→6)-β-D-glucopyranosyloxy]cuminol
  • HY-161119
    Drpitor1a

    		Dynamin Reactive Oxygen Species Cardiovascular Disease Cancer
    Drpitor1a is a potent Drp1 inhibitor. Drpitor1a inhibits mitochondrial ROS production, preventes mitochondrial fission, and improves right ventricular diastolic dysfunction during IR (ischemia reperfusion) injury. Drpitor1a has the potential for the research of lung cancer [1]sup .
    Drpitor1a
  • HY-128845
    PROTAC CRBN Degrader-1

    		PROTACs Cancer
    PROTAC CRBN Degrader-1 comprises a cereblon (CRBN) ligand binding group, a linker and an von Hippel-Landau (VHL) binding group. PROTAC CRBN Degrader-1 is an cereblon (CRBN) degrader .
    PROTAC CRBN Degrader-1
  • HY-126906R
    Milbemycin A4 (Standard)

    		Antibiotic P-glycoprotein Cancer
    Milbemycin A4 (Standard) is the analytical standard of Milbemycin A4. This product is intended for research and analytical applications. Milbemycin A4 inhibits P-glycoprotein activity, and reverses multidrug resistance of tumor cells. Milbemycins are a family of macrolide antibiotics with insecticidal and acaricidal activity [1]sup> .
    Milbemycin A4 (Standard)
  • HY-136262
    CRBN-6-5-5-VHL

    		PROTACs Cancer
    CRBN-6-5-5-VHL is a potent and selective von Hippel-Lindau-based cereblon (CRBN) degrader with a DC50 value of 1.5 nM. CRBN-6-5-5-VHL has almost no effect on the degradation of the neo-substrates IKZF1 and IKZF3 .
    CRBN-6-5-5-VHL
  • HY-138040
    CRBN modulator-1

    		Ligands for E3 Ligase Cancer
    CRBN modulator-1, a Thalidomide analog and a CRBN modulator extracted from WO2020006262A1, compound 10, has an IC50 of 3.5 μM and a Ki of 0.98 μM .
    CRBN modulator-1
  • HY-12741
    LDN-212320
    5 Publications Verification

    LDN-0212320; OSU-0212320

    		 EAAT Neurological Disease
    LDN-212320 (LDN-0212320) is a glutamate transporter (GLT-1)/excitatory amino acid transporter 2 (EAAT2) activator (at translational level). LDN-212320 (LDN-0212320) prevents nociceptive pain by upregulating astroglial GLT-1 expression in the hippocampus and ACC [1]sup .
    LDN-212320
  • HY-A0003S2
    Lenalidomide-13C5,15N

    CC-5013-<sup>13sup>C5,<sup>15sup>N

    		 Ligands for E3 Ligase Apoptosis Molecular Glues Isotope-Labeled Compounds Inflammation/Immunology Cancer
    Lenalidomide- 13C5, 15N is 15N and 13C labeled Lenalidomide (HY-A0003). Lenalidomide (CC-5013), a derivative of Thalidomide, acts as molecular glue. Lenalidomide is an orally active immunomodulator. Lenalidomide (CC-5013) is a ligand of ubiquitin E3 ligase cereblon (CRBN), and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide (CC-5013) specifically inhibits growth of mature B-cell lymphomas, including multiple myeloma, and induces IL-2 release from T cells .
    Lenalidomide-13C5,15N
  • HY-N8824
    Maackiaflavanone

    		Others Others
    Maackiaflavanone (compound 4) is a kind of prenylated flavanone. Maackia can be isolated from M. amurensi.
    Maackiaflavanone
  • HY-150799
    CRBN ligand-1

    		Ligands for E3 Ligase Cancer
    CRBN ligand-1 is a ligand for E3 ligase.
    CRBN ligand-1
  • HY-116881
    SCH 57790

    		mAChR Neurological Disease
    SCH 57790 is a selective antegonist for muscarinic M2 receptor, which increases acetylcholine release, and thus improves cognitive performance. SCH 57790 reverses Scopolamine (HY-N0296)-induced memory deficits in mice, without significant toxicity (100 mg/kg).
    SCH 57790
  • HY-158152
    PROTAC CRBN ligand-2

    		Ligands for E3 Ligase Cancer
    PROTAC CRBN ligand-2 (12) is a Biguanide-PROTAC derivative, with an EC50 of 0.15 mM in KP4 cells. PROTAC CRBN ligand-2 (12) demonstrates the ability to alter levels of mitochondrial proteins, notably complexes I and IV .
    PROTAC CRBN ligand-2
  • HY-Y0850U
    PVA (Mw 31000, 87-89% hydrolyzed, ～630 polymerization)

    Polyvinyl alcohol (Mw 31000, 87-89% hydrolyzed, ～630 polymerization); Poly(Ethenol) (Mw 31000, 87-89% hydrolyzed, ～630 polymerization)

    		 Biochemical Assay Reagents Others
    PVA (Mw 31000, 87-89% hydrolyzed, ～630 polymerization) (Polyvinyl alcohol (Mw 31000, 87-89% hydrolyzed, ～630 polymerization); Poly(Ethenol) (Mw 31000, 87-89% hydrolyzed, ～630 polymerization)) is a biocompatible, biodegradable, nontoxic and hydrophilic synthetic polymer. PVA (Mw 31000, 87-89% hydrolyzed, ～630 polymerization) can be used to produce bone tissue engineering scaffold [1]sup .
    PVA (Mw 31000, 87-89% hydrolyzed, ～630 polymerization)
  • HY-159164
    PROTAC CRBN ligand-3

    		Ligands for Target Protein for PROTAC Cancer
    PROTAC CRBN ligand-3 is a target protein ligand of RGB110 (HY-159087).
    PROTAC CRBN ligand-3
  • HY-B0149S3
    Tranexamic acid-13C2,15N

    Cyclocapron-<sup>13sup>C2,<sup>15sup>N

    		 Isotope-Labeled Compounds Inflammation/Immunology
    Tranexamic acid- 13C2, 15N (Cyclocapron- 13C2, 15N) is the 13C2 and 15N labeled Tranexamic acid. Tranexamic acid is an antifibrinolytic agent that alleviates liver damage and fibrosis in mouse models of chronic bile duct injury .
    Tranexamic acid-13C2,15N
  • HY-RS03143
    CRBN Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    CRBN Human Pre-designed siRNA Set A contains three designed siRNAs for CRBN gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    CRBN Human Pre-designed siRNA Set A
    CRBN Human Pre-designed siRNA Set A
  • HY-163922
    CRBN ligand-1-piperidine-Me

    		E3 Ligase Ligand-Linker Conjugates Cancer
    CRBN ligand-1-piperidine-Me is an E3 ligase ligand-linker conjugate.
    CRBN ligand-1-piperidine-Me
  • HY-N3872
    Ethyl β-D-glucopyranoside

    		Others Others
    Ethyl β-D-glucopyranoside (compound 10) is a kind of phenolic compound. Ethyl β-D-glucopyranoside can be isolated from ethanolic extract of Scabiosa stellata LS.
    Ethyl β-D-glucopyranoside
  • HY-D1583
    Cyanine5 DBCO
    1 Publications Verification

    DBCO-Cy5; Cyanine5 dibenzocyclooctyne

    		 Fluorescent Dye Others
    Cyanine5 DBCO (DBCO-Cy5) is a low-toxicity azide reactive probe (NIR fluorescent dye), for imaging azide-labeled biomolecules via a copper-free "click-through" reaction. Cyanine5 DBCO has no apparent cytotoxicity or animal toxicity and shows no damage to the physiological functions of cells other than the target cells (azide-labeled cells). Cyanine5 DBCO can be used to label and track cells in vitro and in vivo (Ex=635 nm, Em=650-700 nm) [2].
    Cyanine5 DBCO
  • HY-N8859
    Isoiridogermanal

    16-Hydroxyiridal

    		 Others Others
    Isoiridogermanal can be isolated from the extract of rhizomes of Iris tectorum Maxim. Isoiridogermanal is cytotoxic with IC50 values of 11 μM and 23 μM against MCF-7 and C32 cell lines.
    Isoiridogermanal
  • HY-156383
    SCO-PEG3-NHS

    		PROTAC Linkers Cancer
    SCO-PEG3-NHS is a PEG linker with a terminal imine(NH) group. SCO-PEG3-NHS is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
    SCO-PEG3-NHS
  • HY-16561S1
    Resveratrol-13C6

    trans-Resveratrol-<sup>13sup>C6; SRT501-<sup>13sup>C6

    		 Isotope-Labeled Compounds IKK Autophagy Mitophagy Sirtuin Apoptosis Bacterial Fungal Antibiotic Keap1-Nrf2 Infection Inflammation/Immunology Cancer
    Resveratrol- 13C6 is the 13C-labeled Resveratrol. Resveratrol (trans-Resveratrol; SRT501), a natural polyphenolic phytoalexin that possesses anti-oxidant, anti-inflammatory, cardioprotective, and anti-cancer properties. Resveratrol (SRT 501) has a wide spectrum of targets including mTOR, JAK, β-amyloid, Adenylyl cyclase, IKKβ, DNA polymerase. Resveratrol also is a specific SIRT1 activator[1][2][3][4]. Resveratrol is a potent pregnane X receptor (PXR) inhibitor[5]. Resveratrol is an Nrf2 activator, ameliorates aging-related progressive renal injury in mice model[6]. Resveratrol increases production of NO in endothelial cells[7].
    Resveratrol-13C6
  • HY-109120S1
    Odevixibat-13C6

    A4250-<sup>13sup>C6

    		 Apical Sodium-Dependent Bile Acid Transporter Isotope-Labeled Compounds Metabolic Disease
    Odevixibat- 13C6 is 13C labeled Odevixibat (HY-109120). Odevixibat (A4250) is a selective and orally active ileal apical sodium-dependent bile acid transporter (ASBT) inhibitor. Odevixibat decreases cholestatic liver and bile duct injury in mice model. Odevixibat has the potential for the treatment of primary biliary cirrhosis .
    Odevixibat-13C6
  • HY-D1327
    Cyanine3 azide chloride

    		Fluorescent Dye Others
    Cyanine3 azide chloride, an analog of Cy3 azide, is a potent green fluorescent dye. Cyanine3 azide chloride uses click chemistry coupled with Alkyne-labeled proteins. Cyanine3 azide chloride can be detected by fluorometers, imagers, and microscopes. (λex=684 nm, λem=710 nm) [1]sup >. Cyanine3 azide (chloride) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    Cyanine3 azide chloride
  • HY-N0733S2
    Glucosamine-13C,15N hydrochloride

    D-(+)-Glucosamine-<sup>13sup>C,<sup>15sup>N hydrochloride; Chitosamine-<sup>13sup>C,<sup>15sup>N hydrochloride

    		 Isotope-Labeled Compounds Autophagy Endogenous Metabolite HIF/HIF Prolyl-Hydroxylase Reactive Oxygen Species Inflammation/Immunology Cancer
    Glucosamine- 13C, 15N (hydrochloride) is the 13C and 15N labeled Glucosamine hydrochloride. Glucosamine hydrochloride (D-Glucosamine hydrochloride) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, i
    Glucosamine-13C,15N hydrochloride
  • HY-B0271S1
    Pyrazinamide-13C,15N

    Pyrazinecarboxamide-<sup>13sup>C,<sup>15sup>N; Pyrazinoic acid amide-<sup>13sup>C,<sup>15sup>N

    		 Autophagy Antibiotic Bacterial Isotope-Labeled Compounds Infection
    Pyrazinamide- 13C, 15N is 15N and 13C labeled Pyrazinamide (HY-B0271). Pyrazinamide (Pyrazinecarboxamide; Pyrazinoic acid amide) is a potent and orally active antitubercular antibiotic. Pyrazinamide is a proagent that is converted to the active form pyrazinoic acid (POA) by PZase/nicotinamidase encoded by the pncA gene in M. tuberculosis.
    Pyrazinamide-13C,15N
  • HY-N0650S6
    L-Serine1-13C,15N

    (-)-Serine-<sup>13sup>C,<sup>15sup>N; (S)-Serine-<sup>13sup>C,<sup>15sup>N

    		 Isotope-Labeled Compounds Endogenous Metabolite Cancer
    L-Serine1- 13C, 15N is the 13C- and 15N-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.
    L-Serine1-13C,15N
  • HY-109506S9
    DPPC-13C2

    129Y83-<sup>13sup>C2

    		 Isotope-Labeled Compounds Endogenous Metabolite Liposome Others
    DPPC-13C2 is a deuterated labeled DPPC . DPPC (129Y83) is a phosphoglyceride that can be used to prepare lipid monolayers, bilayers, and liposomes. DPPC is the main lipid component of pulmonary surfactant. Dppc-liposome can be effectively used as a delivery vector to induce an immune response against GSL antigen in mice .
    DPPC-13C2
  • HY-Y0418S
    Dulcite-13C

    Dulcitol-<sup>13sup>C; Melampyrit-<sup>13sup>C; NSC 1944-<sup>13sup>C

    		 Isotope-Labeled Compounds Endogenous Metabolite Others
    Dulcite- 13C is the 13C labeled Dulcite. Dulcite is a sugar alcohol with a slightly sweet taste which is a metabolic breakdown product of galact[1][2].
    Dulcite-13C
  • HY-13771S1
    Ursodeoxycholic acid-13C

    Ursodeoxycholate-<sup>13sup>C; Ursodiol-<sup>13sup>C; UDCA-<sup>13sup>C

    		 Isotope-Labeled Compounds G protein-coupled Bile Acid Receptor 1 FXR Endogenous Metabolite Cancer
    Ursodeoxycholic acid- 13C is the 13C labeled Ursodeoxycholic acid. Ursodeoxycholic acid (Ursodeoxycholate) is a secondary bile acid issued from the transformation of (cheno)deoxycholic acid by intestinal bacteria, acting as a key regulator of the intestinal barrier integrity and essential for lipid metabolism. Ursodeoxycholic acid acts as signaling molecule, exerting its effects by interacting with bile acid activated receptors, including G-protein coupled bile acid receptor 5 (TGR5, GPCR19) and the farnesoid X receptor (FXR). Ursodeoxycholic acid can be used for the research of a variety of hepatic and gastrointestinal diseases. Orally active[1][2].
    Ursodeoxycholic acid-13C
  • HY-A0061S
    Trifluridine-13C,15N2

    Trifluorothymidine-<sup>13sup>C,<sup>15sup>N2; 5-Trifluorothymidine-<sup>13sup>C,<sup>15sup>N2; TFT-<sup>13sup>C,<sup>15sup>N2

    		 Thymidylate Synthase Nucleoside Antimetabolite/Analog HSV Orthopoxvirus Cancer
    Trifluridine- 13C, 15N2 is the 13C and 15N labeled Trifluridine[1]. Trifluridine (Trifluorothymidine;5-Trifluorothymidine;TFT) is an irreversible thymidylate synthase inhibitor, and thereby suppresses DNA synthesis. Trifluridine is an antiviral agent for herpes simplex virus (HSV) infection. Trifluorothymidine also has anti-orthopoxvirus activity[2].
    Trifluridine-13C,15N2
  • HY-B0389S10
    D-Glucose-13C

    Glucose-<sup>13sup>C; D-(+)-Glucose-<sup>13sup>C; Dextrose-<sup>13sup>C

    		 Endogenous Metabolite Metabolic Disease
    D-Glucose- 13C is the 13C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].
    D-Glucose-13C
  • HY-B0389S29
    D-Glucose-18O

    Glucose-<sup>18sup>O; D-(+)-Glucose-<sup>18sup>O; Dextrose-<sup>18sup>O

    		 Endogenous Metabolite Metabolic Disease Cancer
    D-Glucose- 18O is the 18O labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules
    D-Glucose-18O
  • HY-13613S2
    Dutasteride-13C,15N,d

    GG 745-<sup>13sup>C,<sup>15sup>N,d; GI 198745-<sup>13sup>C,<sup>15sup>N,d

    		 5 alpha Reductase Apoptosis Isotope-Labeled Compounds Cancer
    Dutasteride- 13C, 15N,d is 15N and deuterated labeled Dutasteride (HY-13613). Dutasteride (GG745) is a potent inhibitor of both 5α-reductase isozymes. Dutasteride may possess off-target effects on the androgen receptor (AR) due to its structural similarity to DHT .
    Dutasteride-13C,15N,d
  • HY-13458S1
    Droxidopa-13C2,15N hydrochloride

    L-DOPS-<sup>13sup>C2,<sup>15sup>N hydrochloride; DOPS-<sup>13sup>C2,<sup>15sup>N hydrochloride; SM5688-<sup>13sup>C2,<sup>15sup>N hydrochloride

    		 Adrenergic Receptor Isotope-Labeled Compounds Neurological Disease
    Droxidopa- 13C2, 15N (hydrochloride) is deuterium labeled Droxidopa. Droxidopa(L-DOPS), the mixture of Droxidopa (w/w80%) and Pharmaceutical starch (w/w20%), acts as a proagent to the neurotransmitters norepinephrine (noradrenaline) and epinephrine (adrenaline); Droxidopa(L-DOPS) is capable of crossing the protective blood–brain barrier[1][2].
    Droxidopa-13C2,15N hydrochloride
  • HY-66005S4
    Acetaminophen-13C2,15N

    Paracetamol-<sup>13sup>C2,<sup>15sup>N; 4-Acetamidophenol-<sup>13sup>C2,<sup>15sup>N; 4'-Hydroxyacetanilide-<sup>13sup>C2,<sup>15sup>N

    		 COX Bacterial Histone Acetyltransferase Parasite Endogenous Metabolite Inflammation/Immunology
    Acetaminophen- 13C2, 15N is the 13C and 15N labeled Acetaminophen[1]. Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM;is a widely used antipyretic and analgesic agent[2][3][4]. Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor[5].
    Acetaminophen-13C2,15N
  • HY-15236S1
    PSI-6206-d1,13C,15N2

    RO 2433--d<sup>1sup>,<sup>13sup>C,<sup>15sup>N2; GS-331007--d<sup>1sup>,<sup>13sup>C,<sup>15sup>N2

    		 HCV Isotope-Labeled Compounds Infection
    PSI-6206-d1, 13C, 15N2 is 15N and 13C labeled PSI-6206 (HY-15236). PSI-6206 (RO 2433) is the deaminated derivative of PSI-6130, which is a potent and selective inhibitor of HCV NS5B polymerase. PSI-6206 low potently inhibits HCV replicon with EC90 of >100 μM.
    PSI-6206-d1,13C,15N2
  • HY-N1480S
    (-)-Fucose-13C

    6-Desoxygalactose-<sup>13sup>C; L-(-)-Fucose-<sup>13sup>C; L-Galactomethylose-<sup>13sup>C

    		 Isotope-Labeled Compounds Endogenous Metabolite Parasite Infection Metabolic Disease
    (-)-Fucose- 13C is the 13C labeled (-)-Fucose. (-)-Fucose is classified as a member of the hexoses, plays a role in A and B blood group antigen substructure determination, selectin-mediated leukocyte-endothelial adhesion, and host-microbe interacti[1]
    (-)-Fucose-13C
  • HY-131887
    Pomalidomide-C6-COOH

    		E3 Ligase Ligand-Linker Conjugates Cancer
    Pomalidomide-C6-COOH is the pomalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Pomalidomide-6-OH can be connected to the ligand for protein by a linker to form PROTAC .
    Pomalidomide-C6-COOH
  • HY-Y1250S6
    Fmoc-Gly-OH-13C2,15N

    Fmoc glycine-<sup>13sup>C2,<sup>15sup>N; N-(9-Fluorenylmethoxycarbonyl)glycine-<sup>13sup>C2,<sup>15sup>N; N-Fluorenylmethoxycarbonylglycine-<sup>13sup>C2,<sup>15sup>N; NPC 14692-<sup>13sup>C2-<sup>15sup>N; NSC 334288-<sup>13sup>C2,<sup>15sup>N; [[[(9H-Fluoren-9-yl)methoxy]carbonyl]amino]acetic acid-<sup>13sup>C2,<sup>15sup>N

    		 Isotope-Labeled Compounds Influenza Virus Bacterial Infection
    Fmoc-Gly-OH- 13C2, 15N is a 15N-labeled and 13C-labled Crystal Violet. Crystal violet (Basic Violet 3) is a triarylmethane dye. Crystal Violet (Gentian Violet) has antiviral effects against H1N1 and also has prominent bactericidal activities.
    Fmoc-Gly-OH-13C2,15N
  • HY-N3980
    Guaiol

    Champacol; Guaiac alcohol

    		 Autophagy RAD51 Infection Cardiovascular Disease Inflammation/Immunology Cancer
    Guaiol is a sesquiterpenoid alcohol with oral activity found in various traditional Chinese medicines, exhibiting biological activities such as anti-proliferative, autophagy-promoting, insecticidal, anti-anxiety, anti-inflammatory, diuretic, and blood pressure-lowering effects. Guaiol induces apoptosis in non-small cell lung cancer cells by regulating the stability of RAD51 through autophagy modulation. Guaiol can also act directly on parasites, inhibiting their growth by affecting the kinetoplast, mitochondrial matrix and plasma membrane of the promastigotes. Guaiol kills amastigotes at an IC50 of 0.01 µg/mL. Guaiol can be used in research related to cancer, infections, cardiovascular diseases, and inflammatory conditions [4]sup .
    Guaiol
  • HY-Z0283S
    Benzamide-15N

    Benzenecarboxamide-<sup>15sup>N; Phenylamide-<sup>15sup>N

    		 Endogenous Metabolite PARP Others
    Benzamide- 15N is a 15N-labeled Benzamide. Benzamide inhibits poly(ADP-ribose) polymerase (PARP)[1][2].
    Benzamide-15N

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