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R

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3180

Inhibitors & Agonists

2

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44

Fluorescent Dye

47

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296

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1

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98

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351

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Products

761

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221

Isotope-Labeled Compounds

128

Antibodies

63

Click Chemistry

187

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-155079A
    (R)-DZD1516

    		Others Others
    (R)-DZD1516 is the R enantiomer of DZD1516 (HY-155079). DZD1516 is a potent and selective HER2 inhibitor .
    (R)-DZD1516
  • HY-19778
    (R)-BPO-27
    1 Publications Verification

    		 CFTR Autophagy Inflammation/Immunology
    (R)-BPO-27, the R enantiomer of BPO-27, is a potent, orally active and ATP-competitive CFTR inhibitor with an IC50 of 4 nM.
    (R)-BPO-27
  • HY-148516A
    (R)-MPH-220

    		Myosin Neurological Disease
    (R)-MPH-220 is the R isomer of MPH-220 (HY-148516). MPH-220 is a selective and orally active inhibitor of skeletal muscle myosin-2. MPH-220 enables muscle relaxation. MPH-220 is anti-spastic agent that can be used in the research of spasticity and muscle stiffness .
    (R)-MPH-220
  • HY-N6937
    (R,R)-Secoisolariciresinol diglucoside

    (R,R)-SDG; (R,R)-LGM2605

    		 Others Inflammation/Immunology
    (R,R)-Secoisolariciresinol diglucoside ((R,R)-SDG) is the minor isomer of Secoisolariciresinol diglucoside in flaxseed. (R,R)-Secoisolariciresinol diglucoside ((R,R)-SDG) possesses antioxidant and free radical scavenging activities and DNA-radioprotective properties. (R,R)-Secoisolariciresinol diglucoside ((R,R)-SDG) inhibits myeloperoxidase (MPO) activity by suppressing both the peroxidase and chlorination cyclesin inflammatory cells .
    (R,R)-Secoisolariciresinol diglucoside
  • HY-B0102C
    (R)-Fluoxetine hydrochloride

    		Serotonin Transporter Neurological Disease
    (R)-Fluoxetine hydrochloride, an antidepressant, is serotonin reuptake inhibitor (SSRI). (R)-Fluoxetine hydrochloride has modest affinity at the 5-HT2A and 5-HT2C receptors .
    (R)-Fluoxetine hydrochloride
  • HY-13956C
    (R)-Pioglitazone

    (R)-U 72107

    		 PPAR Neurological Disease
    (R)-Pioglitazone ((+)-pioglitazone) is the R enantiomer of Pioglitazone (HY-13956). (R)-Pioglitazone is an orally active and selective peroxisome proliferator-activated receptor (PPARγ) agonist with high affinity binding to the PPARγ ligand-binding domain. (R)-Pioglitazone can be used for the research of Alzheimer's disease .
    (R)-Pioglitazone
  • HY-106334
    Noberastine

    R 64947

    		 Histamine Receptor Neurological Disease
    Noberastine is a potent Histamine H1 antagonist. Noberastine has specific peripheral antihistamine activity .
    Noberastine
  • HY-B0761
    (R,R)-Glycopyrrolate

    (R,R)-Glycopyrronium bromide; (R,R)-Glycopyrrolate bromide

    		 mAChR Neurological Disease
    (R,R)-Glycopyrrolate ((R,R)-Glycopyrronium (bromide); (R,R)-Glycopyrrolate (bromide)) is an anticholinergic agent. (R,R)-Glycopyrrolate ((R,R)-Glycopyrronium (bromide); (R,R)-Glycopyrrolate (bromide)) has the ability to reduce the frequency of drooling in vivo with developmental disabilities .
    (R,R)-Glycopyrrolate
  • HY-14560A
    (R,R)-Reboxetine mesylate

    (R,R)-FCE20124 mesylate; (R,R)-PNU155950E mesylate

    		 Adrenergic Receptor mAChR Neurological Disease
    (R,R)-Reboxetine mesylate is an antidepressant agent with great bioavailability. (R,R)-Reboxetine is the enantiomer of Reboxetine, which is a selective noradrenaline reuptake inhibitor. Reboxetine consists of (R,R) and (S,S) enantiomer, has low affinity for alpha-adrenergic and muscarinic receptors and low toxicity in animals .
    (R,R)-Reboxetine mesylate
  • HY-121814A
    (R)-Acenocoumarol

    (R)-Acenocoumarin; (R)-Nicoumalone

    		 Others Others
    (R)-Acenocoumarol ((R)-Acenocoumarin; (R)-Nicoumalone) is a short-acting oral anticoagulant that, like warfarin, works by inhibiting vitamin K epoxide reductase. In vitro evaluations have shown that (R)-Acenocoumarol ((R)-Acenocoumarin; (R)-Nicoumalone) has a higher intrinsic anticoagulant potency than warfarin and phenprocoumon. (R)-Acenocoumarol ((R)-Acenocoumarin; (R)-Nicoumalone) has a single chiral center that produces two different enantiomeric forms. (R)-(R)-Acenocoumarol ((R)-Acenocoumarin; (R)-Nicoumalone) has a longer plasma elimination half-life (6.6 hours) and a slower plasma clearance rate (1.9 L/hour) compared to the (S)-enantiomer (1.8 hours, 28.5 L/hour). (R)-(R)-Acenocoumarol ((R)-Acenocoumarin; (R)-Nicoumalone) is a more potent anticoagulant in vivo than the (S)-enantiomer.
    (R)-Acenocoumarol
  • HY-U00092B
    (R,R)-BAY-Y 3118

    		Bacterial Infection
    (R,R)-BAY-Y 3118 is the R-enantiomer of BAY-Y 3118. (R,R)-BAY-Y 3118 shows weak bactericidal activity .
    (R,R)-BAY-Y 3118
  • HY-N6937S1
    (R,R)-Secoisolariciresinol diglucoside-d6

    (R,R)-SDG-d6; (R,R)-LGM2605-d6

    		 Isotope-Labeled Compounds Inflammation/Immunology
    (R,R)-Secoisolariciresinol diglucoside-d6 is deuterated labeled (R,R)-Secoisolariciresinol diglucoside (HY-N6937). (R,R)-Secoisolariciresinol diglucoside ((R,R)-SDG) is the minor isomer of Secoisolariciresinol diglucoside in flaxseed. (R,R)-Secoisolariciresinol diglucoside ((R,R)-SDG) possesses antioxidant and free radical scavenging activities and DNA-radioprotective properties. (R,R)-Secoisolariciresinol diglucoside ((R,R)-SDG) inhibits myeloperoxidase (MPO) activity by suppressing both the peroxidase and chlorination cyclesin inflammatory cells .
    (R,R)-Secoisolariciresinol diglucoside-d6
  • HY-137453C
    (R,1R)-Tenofovir amibufenamide

    (R,1R)-HS-10234

    		 Others Others
    (R,1R)-Tenofovir amibufenamide ((R,1R)-HS-10234) can be used for the purifying a tenofovir prodrug. Tynofovir (tenofovir) is a nucleoside acids reverse transcriptase inhibitors .
    (R,1R)-Tenofovir amibufenamide
  • HY-N6937R
    (R,R)-Secoisolariciresinol diglucoside (Standard)

    		Others Inflammation/Immunology
    (R,R)-Secoisolariciresinol diglucoside (Standard) is the analytical standard of (R,R)-Secoisolariciresinol diglucoside. This product is intended for research and analytical applications. (R,R)-Secoisolariciresinol diglucoside ((R,R)-SDG) is the minor isomer of Secoisolariciresinol diglucoside in flaxseed. (R,R)-Secoisolariciresinol diglucoside ((R,R)-SDG) possesses antioxidant and free radical scavenging activities and DNA-radioprotective properties. (R,R)-Secoisolariciresinol diglucoside ((R,R)-SDG) inhibits myeloperoxidase (MPO) activity by suppressing both the peroxidase and chlorination cyclesin inflammatory cells .
    (R,R)-Secoisolariciresinol diglucoside (Standard)
  • HY-14658B
    (R)-Thalidomide

    (R)-(+)-Thalidomide

    		 Molecular Glues Ligands for E3 Ligase Autophagy Apoptosis Metabolic Disease
    (R)-Thalidomide ((R)-(+)-Thalidomide) is the R-enantiomer of Thalidomide. (R)-Thalidomide has psychomotor stabilizing properties .
    (R)-Thalidomide
  • HY-12170B
    (R)-Prinomastat

    (R)-AG3340; (R)-KB-R9896

    		 Others Cancer
    (R)-Prinomastat ((R)-AG3340) is the R-isomer of Prinomastat (HY-12170) (a MMP Inhibitor) .
    (R)-Prinomastat
  • HY-A0021C
    (R,R)-Palonosetron Hydrochloride

    		5-HT Receptor Inflammation/Immunology
    (R,R)-Palonosetron Hydrochloride is the active enantiomer of Palonosetron.
    (R,R)-Palonosetron Hydrochloride
  • HY-59125
    (R,R)-(+)-Hydrobenzoin

    		Endogenous Metabolite Others
    (R,R)-(+)-Hydrobenzoin is a organocatalysts .
    (R,R)-(+)-Hydrobenzoin
  • HY-17554
    (R)-Oxiracetam

    (R)-(+)-Oxiracetam; (R)-ISF2522

    		 Others Neurological Disease
    (R)-Oxiracetam is the (R)-enantiomer of the nootropic drug oxiracetam.
    (R)-Oxiracetam
  • HY-W015851
    (R)-3-Hydroxybutanoic acid sodium
    5 Publications Verification

    (R)-(-)-3-Hydroxybutanoic acid sodium; (R)-3-Hydroxybutyric acid sodium

    		 Endogenous Metabolite Metabolic Disease
    (R)-3-Hydroxybutanoic acid sodium ((R)-3-Hydroxybutyric acid) is a metabolite converted from acetoacetic acid catalyzed by 3-hydroxybutyrate dehydrogenase. (R)-3-Hydroxybutanoic acid sodium can function as a nutrition source, and as a precursor for vitamins, antibiotics and pheromones .
    (R)-3-Hydroxybutanoic acid sodium
  • HY-B0352B
    (R)-Mirtazapine

    (R)-Org3770; (R)-6-Azamianserin

    		 5-HT Receptor Neurological Disease
    (R)-Mirtazapine ((R)-Org3770) is a R(−)-enantiomer of Mirtazapine with antinociceptive properties in an animal model of acute thermal nociception. (R)-Mirtazapine is a 5-HT3 receptor antagonist. (R)-Mirtazapine is mainly metabolized by CYP3A4 .
    (R)-Mirtazapine
  • HY-100617B
    (R)-4CPG

    (R)-4-Carboxyphenylglycine

    		 Others Others
    (R)-4CPG ((R)-4-Carboxyphenylglycine) is a less avtive R-enantiomer of (S)-4CPG .
    (R)-4CPG
  • HY-B0006C
    (R)-Carvedilol

    (R)-BM 14190

    		 Adrenergic Receptor Cardiovascular Disease
    (R)-Carvedilol ((R)-BM 14190), the R-enantiomer of Carvedilol, is a non-selective β/α-1 blocker. (R)-Carvedilol exerts protection against the vascular or cardiac toxicity of Doxorubicin (DOX) .
    (R)-Carvedilol
  • HY-15431A
    (R)-Capivasertib

    (R)-AZD5363

    		 Others Cancer
    (R)-Capivasertib ((R)-AZD5363) is the R-enantiomer of Capivasertib (HY-15431) .
    (R)-Capivasertib
  • HY-78131B
    (R)-(-)-Ibuprofen
    2 Publications Verification

    (R)-Ibuprofen

    		 NF-κB Inflammation/Immunology Cancer
    (R)-(-)-Ibuprofen is the R enantiomer of Ibuprofen, inactive on COX, inhibits NF-κB activation; (R)-(-)-Ibuprofen exhibits anti-inflammatory and antinociceptive effects.
    (R)-(-)-Ibuprofen
  • HY-128888
    (R,R)-GSK321

    		Isocitrate Dehydrogenase (IDH) Cancer
    (R,R)-GSK321 is a wild-type isocitrate dehydrogenase 1 (WT IDH1) inhibitor with an IC50 value of 120 nM. (R,R)-GSK321 as a mutant R132H IDH1 inhibitor, is an isomer of GSK321 with some wild-type cross reactivity .
    (R,R)-GSK321
  • HY-14307A
    (R)-Necrocide 1

    		Others Cancer
    (R)-Necrocide 1 (compound (R)-38) a potent anticancer agent. (R)-Necrocide 1 has antiproliferative activity .
    (R)-Necrocide 1
  • HY-109854A
    (R)-Lisofylline

    (R)-Lisophylline

    		 STAT Metabolic Disease Inflammation/Immunology
    (R)-Lisofylline ((R)-Lisophylline) is a (R)-enantiomer of the metabolite of Pentoxifylline with anti-inflammatory properties. (R)-Lisofylline is a lysophosphatidic acid acyltransferase inhibitor with an IC50 of 0.6 µM and interrupts IL-12 signaling-mediated STAT4 activation. (R)-Lisofylline has the potential for type 1 diabetes, autoimmune disorders research .
    (R)-Lisofylline
  • HY-W756217
    (R)-Monepantel

    (R)-AAD1566

    		 Others Others
    (R)-Monepantel (AAD2224) is the optical R-enantiomer of monepantel. (R)-Monepantel has no nematocidal effect, is inactive .
    (R)-Monepantel
  • HY-103451
    (R,R)-THC

    		Estrogen Receptor/ERR Metabolic Disease
    (R,R)-THC is an ERα agonist and an ERβ antagonist, with Kis of 9.0 nM and 3.6 nM for ERα and ERβ, respectively. (R,R)-THC has higher relative binding affinity for ERβ than ERα with the values of 25 and 3.6 .
    (R,R)-THC
  • HY-16723A
    (R)-Funapide

    (R)-TV 45070; (R)-XEN402

    		 Sodium Channel Neurological Disease
    (R)-Funapide ((R)-TV 45070) is the less active R-enantiomer of Funapide. Funapide is a potent Nav1.7 sodium channel blocker that can be used for pain research .
    (R)-Funapide
  • HY-19111
    R-82150

    TIBO-R 82150

    		 HIV Reverse Transcriptase Infection
    R-82150 (TIBO-R 82150) is an HIV-1 reverse transcriptase inhibitor that blocks the reverse transcription of viral RNA by binding to the non-substrate binding site of reverse transcriptase, thereby inhibiting viral replication. R-82150 does not inhibit the replication of HIV-2, other RNA viruses, and DNA viruses .
    R-82150
  • HY-101474B
    (R)-Zanubrutinib

    (R)-BGB-3111

    		 Btk Others
    (R)-Zanubrutinib is the R enantiomer of Zanubrutinib (HY-101474A). (R)-Zanubrutinib inhibits Bruton's tyrosine kinase (Btk) with an IC50 of 11 nM.
    (R)-Zanubrutinib
  • HY-14948A
    (R)-Carisbamate

    (R)-RWJ-333369

    		 Others Neurological Disease
    (R)-Carisbamate ((R)-RWJ-333369) is the R-Enantiomer of Carisbamate (HY-14948). Carisbamate is an orally active neuromodulator .
    (R)-Carisbamate
  • HY-W051723
    (R)-3-Hydroxybutanoic acid
    5 Publications Verification

    (R)-(-)-3-Hydroxybutanoic acid; (R)-3-Hydroxybutyric acid

    		 Endogenous Metabolite Others
    (R)-3-Hydroxybutanoic acid is a metabolite, and converted from acetoacetic acid catalyzed by 3-hydroxybutyrate dehydrogenase. (R)-3-Hydroxybutanoic acid has applications as a nutrition source and as a precursor for vitamins, antibiotics and pheromones .
    (R)-3-Hydroxybutanoic acid
  • HY-75087
    (R)-pyrrolidine-2-carboxylic acid

    (+)-(R)-Proline; (R)-(+)-Proline; (R)-2-Carboxypyrrolidine; (R)-Proline

    		 Endogenous Metabolite Metabolic Disease
    (R)-pyrrolidine-2-carboxylic acid ((+)-(R)-Proline) is a proline isomer that exhibits high renal and hepatotoxicity in rats. (R)-pyrrolidine-2-carboxylic acid can be used to study amino acid metabolism and toxicity mechanisms .
    (R)-pyrrolidine-2-carboxylic acid
  • HY-100615A
    R 80123

    		Phosphodiesterase (PDE) Cardiovascular Disease
    R 80123 is the Z-isomer of R 79595, is also a highly selective phosphodiesterase inhibitor.
    R 80123
  • HY-106841
    Draflazine

    R-75231; R88021

    		 Others Inflammation/Immunology
    Draflazine (R-75231) is a ENT1 inhibitor. Draflazine (R-75231) completely reverses the hypersensitivity in the complete Freund’s adjuvant (CFA) model of mechanical hyperalgesia and the carrageenan inflammation model of thermal and mechanical hyperalgesia .
    Draflazine
  • HY-15584C
    (R)-Taltobulin

    (R)-HTI-286; (R)-SPA-110

    		 Others Others
    (R)-Taltobulin ((R)-HTI-286) can be used as a reference substance .
    (R)-Taltobulin
  • HY-10572A
    (R)-Efavirenz

    (R)-DMP 266; (R)-EFV; (R)-L-743726

    		 Reverse Transcriptase Infection
    (R)-Efavirenz ((R)-DMP 266) is a non-nucleoside reverse transcriptase inhibitor that acts by non-competitive inhibition of the viral enzyme. (R)-Efavirenz can be metabolized by CYP2B6 to 8-hydroxyefavirenz in a highly stereoselective manner. (R)-Efavirenz is promising to be a useful probe for the CYP2B6 active site and catalytic mechanisms .
    (R)-Efavirenz
  • HY-I0636
    (R)-Apremilast

    (R)-CC-10004

    		 Others Inflammation/Immunology
    (R)-Apremilast ((R)-CC-10004) is a enantiomer of Apremilast .
    (R)-Apremilast
  • HY-15452B
    (R)-Selisistat

    (R)-EX-527

    		 Sirtuin Cancer
    (R)-Selisistat ((R)-EX-527) is a R-enantiomer of Selisistat. Selisistat (EX-527) is a potent and selective SIRT1 inhibitor with IC50 of 98 nM.
    (R)-Selisistat
  • HY-W062695
    (R)-Acalabrutinib

    (R)-ACP-196

    		 Btk Cancer
    (R)-Acalabrutinib ((R)-ACP-196) is the enantiomer of Acalabrutinib (HY-17600). (R)-Acalabrutinib is an inhibitor for Bruton’s tyrosine kinase (BTK) .
    (R)-Acalabrutinib
  • HY-132821B
    (R)-Irsenontrine

    (R)-E2027

    		 Phosphodiesterase (PDE) Neurological Disease
    (R)-Irsenontrine ((R)-E2027), the R-enantiomer of Irsenontrine (HY-132821), is a potent phosphodiesterase 9 (PDE9) inhibitor with an IC50 value of 0.041 μM. (R)-Irsenontrine can be used for the research of neurological diseases .
    (R)-Irsenontrine
  • HY-15187A
    (R)-Filanesib

    (R)-ARRY-520

    		 Kinesin Cancer
    (R)-Filanesib ((R)-ARRY-520) is the R-enantiomer of Filanesib (HY-15187). Filanesib is a synthetic kinesin spindle protein (KSP) inhibitor with an IC50 of 6 nM.
    (R)-Filanesib
  • HY-B0010E
    Arformoterol maleate

    (R,R)-Formoterol maleate

    		 Adrenergic Receptor Inflammation/Immunology
    Arformoterol ((R,R)-Formoterol) maleate, the (R,R)-enantiomer of Formoterol, is a long-acting β2-adrenergic receptor (β2-AR) agonist, with a Kd of 2.9 nM. Arformoterol maleate can be used for the research of chronic obstructive pulmonary disease (COPD) .
    Arformoterol maleate
  • HY-165976
    rel-(9R,10R)-9,10-Dihydroxyhexadecanoic acid

    		Others Metabolic Disease
    rel-(9R,10R)-9,10-Dihydroxyhexadecanoic acid is an ester product.
    rel-(9R,10R)-9,10-Dihydroxyhexadecanoic acid
  • HY-120207
    (R)-GDC-0927

    (R)-SRN-927

    		 Others Others
    (R)-GDC-0927 ((R)-SRN-927) is a (R)-enantiomer of GDC-0927 (HY-111484) .
    (R)-GDC-0927
  • HY-108263B
    (R)-3-Hydroxy Midostaurin

    (R)-CGP52421

    		 FLT3 Drug Metabolite Cancer
    (R)-3-Hydroxy Midostaurin ((R)-CGP52421) is a potent kinases inhibitor. (R)-3-Hydroxy Midostaurin is a major metabolite of midostaurin (PKC412; HY-10230) undergoing by the hepatic CYP3A4 enzyme. (R)-3-Hydroxy Midostaurin has the potential for acute myeloid leukemia (AML) .
    (R)-3-Hydroxy Midostaurin
  • HY-135336
    (R)-Verapamil hydrochloride

    (R)-(+)-Verapamil hydrochloride

    		 P-glycoprotein Apoptosis Cancer
    (R)-Verapamil hydrochloride ((R)-(+)-Verapamil hydrochloride) is a P-Glycoprotein inhibitor. (R)-Verapamil hydrochloride blocks MRP1 mediated transport, resulting in chemosensitization of MRP1-overexpressing cells to anticancer agents .
    (R)-Verapamil hydrochloride

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