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Tri-iso-propyl-d<sub>21</sub>-phosphine carbon disulfide complex-d<sub>21</sub>

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2947

Isotope-Labeled Compounds

Antibodies

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Targets Recommended: PDI P-glycoprotein Arp2/3 Complex

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W004282S

Undecanoic acid-d21 Undecanoate-d<sub>21sub>; Hendecanoic acid-d<sub>21sub>	Fungal Endogenous Metabolite	Cancer
Undecanoic acid-d₂₁ is the deuterium labeled Undecanoic acid. Undecanoic acid (Undecanoate) is a monocarboxylic acid with antimycotic property, which inhibits the production of exocellular keratinase, lipase and the biosynthesis of several phospholipids in T. rubrum[1].

HY-100085S

21-Desacetyldeflazacort-d5 21-desDFZ-d<sub>5sub>	Glucocorticoid Receptor	Inflammation/Immunology
21-Desacetyldeflazacort-d₅ is the deuterium labeled 21-Desacetyldeflazacort[1].

HY-W012351S

Tripropyl phosphate-d21 Tris(1-propyl)phosphate-d<sub>21sub>	Isotope-Labeled Compounds	Others
Tripropyl phosphate-d₂₁ is the deuterium labeled Tripropyl phosphate[1].

HY-151131S

Tri-iso-propyl-d21-phosphine carbon disulfide complex-d21	Isotope-Labeled Compounds	Others
Tri-iso-propyl-d₂₁-phosphine carbon disulfide complex-d₂₁ is the deuterium labeled Tri-iso-propyl-d21-phosphine carbon disulfide complex[1].

HY-RS13999

SUB1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SUB1 Human Pre-designed siRNA Set A contains three designed siRNAs for SUB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SUB1 Human Pre-designed siRNA Set A SUB1 Human Pre-designed siRNA Set A

HY-146227

DNA topoisomerase II inhibitor 1	Topoisomerase Apoptosis	Cancer
DNA topoisomerase II inhibitor 1 (compound 8ed) is a potent DNA topoisomerase II inhibitor. DNA topoisomerase II inhibitor 1 shows anti-proliferative activity. DNA topoisomerase II inhibitor 1 induces apoptosis and cell cycle arrest at sub G1 phase .

HY-W142921S

*Allyl methyl disulfide-d3* methyl prop-2-en-1-yl disulfide-d<sub>3sub>	Isotope-Labeled Compounds	Others
Allyl methyl disulfide-d₃ is deuterated labeled (E)-Oct-2-enal.

HY-W654319

Tri-p-tolyl phosphate-d21 Tricresyl phosphate-d<sub>21sub>	Isotope-Labeled Compounds	Others
Tri-p-tolyl phosphate-d21 is the deuterium labeled Tri-p-tolyl phosphate .

HY-P1565

Transdermal Peptide Disulfide TD 1 disulfide(peptide)	Na+/K+ ATPase	Inflammation/Immunology
Transdermal Peptide Disulfide (TD 1 Disulfide(peptide)) is a 11-amino acid peptide, binds toNa ⁺/K ⁺-ATPase beta-subunit (ATP1B1), and mainly interacts with the C-terminus of ATP1B1. Transdermal Peptide Disulfide can enhance the transdermal delivery of many macromolecules .

HY-W074006

Tris(2-cyanoethyl)phosphine	Biochemical Assay Reagents	Others
Tris(2-cyanoethyl)phosphine is a protein crosslinker. Tris(2-cyanoethyl)phosphine can be used to synthesis copper(I) complexes which shows antitumour activity .

HY-W011599

Diphenyl(p-tolyl)phosphine	Biochemical Assay Reagents	Others
Diphenyl(p-tolyl)phosphine is a biochemical reagent.

HY-137360

Phosphine-biotin	Others	Others
Phosphine-biotin is a labeling reagent that selectively reacts with azido groups on modified proteins through the Staudinger ligation reaction .

HY-Y1213S

Carbon-13C	Isotope-Labeled Compounds	Others
Carbon- ¹³C is the ¹³C labeled Carbon[1].

HY-W013772

Tris(4-methoxyphenyl)phosphine Tris(p-anisyl)phosphine	Biochemical Assay Reagents	Others
Tris(4-methoxyphenyl)phosphine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W008896

Tris(pentafluorophenyl)phosphine	Biochemical Assay Reagents	Others
Tris(perfluorophenyl)phosphine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-10844S1

Pretomanid-d5 PA-824-d<sub>5sub>; (S)-PA 824-d<sub>5sub>	Antibiotic Bacterial Isotope-Labeled Compounds	Infection Cancer
Pretomanid-d₅ is deuterated labeled Pretomanid (HY-10844). Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 μg/mL.

HY-W008707

Tris(4-fluorophenyl)phosphine	Biochemical Assay Reagents	Others
Tris(4-fluorophenyl)phosphine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-70026

Tri(2-methylphenyl)phosphine	Biochemical Assay Reagents	Others
Tri(2-methylphenyl)phosphine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-P1565A

*Transdermal Peptide Disulfide* TFA** TD 1 disulfide(peptide) TFA	Na+/K+ ATPase	Others
Transdermal Peptide Disulfide TFA (TD 1 Disulfide(peptide) TFA) is a 11-amino acid peptide, binds to Na ⁺/K ⁺-ATPase beta-subunit (ATP1B1), and mainly interacts with the C-terminus of ATP1B1. Transdermal Peptide Disulfide TFA can enhance the transdermal delivery of many macromolecules .

HY-W196803

Dipropyl disulfide propyl disulfide; DPDS	Others	Others
Dipropyl disulfide is oxidized to dipropyl thiosulfinate (DPDSO) by rat microsomes. Both flavincontaining monooxygenases (FMO) and cytochrome P450 enzymes (CYPs) are involved in dipropyl disulfide oxidation. Dipropyl disulfide forms two metabolites: propylglutathione sulfide conjugate and propylthiol .

HY-Y1177

Diphenyl disulfide Phenyl disulfide	Endogenous Metabolite	Metabolic Disease
Diphenyl disulfide is an endogenous metabolite.

HY-W009516R

*Dibenzyl disulfide* (Standard)**	Endogenous Metabolite	Metabolic Disease
Dibenzyl disulfide (Standard) is the analytical standard of Dibenzyl disulfide. This product is intended for research and analytical applications. Dibenzyl disulfide is an endogenous metabolite.

HY-B2224R

*Thiamine disulfide* (Standard)**	HIV Endogenous Metabolite	Infection Metabolic Disease
Thiamine disulfide (Standard) is the analytical standard of Thiamine disulfide. This product is intended for research and analytical applications. Thiamine disulfide, a vitamin B1 derivative, is an oxidized dimer of Thiamine. Thiamine disulfide is a potent HIV-1 inhibitor. Thiamine disulfide significantly depresses HIV-1 transactivator (Tat) activity .

HY-123068R

*Captopril disulfide* (Standard)**	Angiotensin-converting Enzyme (ACE)	Cardiovascular Disease
Captopril disulfide (Standard) is the analytical standard of Captopril disulfide. This product is intended for research and analytical applications. Captopril disulfide is a metabolite of Captopril with antihypertensive activity .

HY-B2224

Thiamine disulfide	HIV Endogenous Metabolite	Infection Metabolic Disease
Thiamine disulfide, a vitamin B1 derivative, is an oxidized dimer of Thiamine. Thiamine disulfide is a potent HIV-1 inhibitor. Thiamine disulfide significantly depresses HIV-1 transactivator (Tat) activity .

HY-W009213

3-Nitrophenyl disulfide Bis(3-nitrophenyl) disulfide; Nitrophenide	Parasite	Infection
3-Nitrophenyl disulfide (Bis(3-Nitrophenyl) disulfide) is an inhibitor of mannitol-1-phosphate dehydrogenase (M1PDH) with IC₅₀ of 3 μM. 3-Nitrophenyl disulfide has antiparasitic activity .

HY-131516

Tiopronin-cysteine disulfide	Others	Others
Tiopronin-cysteine disulfide is a disulfide formed by Tiopronin (HY-B0373) and cysteine .

HY-W009516

Dibenzyl disulfide	Endogenous Metabolite	Metabolic Disease
Dibenzyl disulfide is an endogenous metabolite.

HY-W015635R

*Diallyl disulfide* (Standard)**	Others	Cancer
Diallyl disulfide (Standard) is the analytical standard of Diallyl disulfide. This product is intended for research and analytical applications. Diallyl disulfide, an active compound in garlic oil, is an orally active human squalene monooxygenase inhibitor with an IC₅₀ of 400 μM for squalene epoxidation. Diallyl disulfide exhibits obvious anti-inflammatory, anti-oxidative, antidepressant and anti-tumor activities .

HY-Y1666

2,2′-Dipyridyl disulfide	Biochemical Assay Reagents	Others
2,2′-Dipyridyl disulfide is a useful reagent for the determination of sulfhydryl groups. 2,2′-Dipyridyl disulfide is a common reagent in peptide chemistry, often used in oxidation–reduction condensations to form peptide bonds or in coupling reactions to form disulfide-linked heterodimers .

HY-W015635

Diallyl disulfide 1 Publications Verification	Others	Cancer
Diallyl disulfide, an active compound in garlic oil, is an orally active human squalene monooxygenase inhibitor with an IC₅₀ of 400 μM for squalene epoxidation. Diallyl disulfide exhibits obvious anti-inflammatory, anti-oxidative, antidepressant and anti-tumor activities .

HY-125833

Alpha-Naphthoflavone 5+ Cited Publications	Cytochrome P450 Aryl Hydrocarbon Receptor Apoptosis	Cancer
Alpha-Naphthoflavone is an orally active flavonoid that is a potent, competitive inhibitor of aromatase< b>aromatase. < b > IC < sub > 50 < / sub > < / b > and < b > K < sub > I < / sub > < / b > value were 0.5 and 0.2 microns. Alpha-Naphthoflavone can inhibit cell proliferation and induce apoptosis .

HY-W011500

TCEP hydrochloride 5+ Cited Publications Tris(2-carboxyethyl)phosphine hydrochloride	Others	Others
TCEP hydrochloride (Tris(2-carboxyethyl)phosphine hydrochloride) is a non-thiol reducing agent that is more stable and produces a faster S-S reductive reaction than other chemical reductants. TCEP hydrochloride is a trialkylphosphine, selectively reduces protein disuldes without altering the properties or interacting with thiol-directed agents in the reaction mixture. TCEP hydrochloride is also a commonly used reducing agent in the DNA/AuNP chemistry .

HY-N7436

Methyl propyl disulfide	Others	Cancer
Methyl propyl disulfide is an volatile sulfur-containing compound produced in garlic and onions with anticaner effect .

HY-B2173

*Thiamine disulfide* dinitrate**	Biochemical Assay Reagents	Others
Thiamine Disulfide Nitrate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-P2927

*Protein disulfide* isomerase**	Others	Others
Protein disulfide isomerase is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-135174

L-Cysteine-glutathione disulfide	Endogenous Metabolite	Infection
L-Cysteine-glutathione disulfide is a metabolite in plasma that can be used in biomarker studies for tuberculosis cure .

HY-N7436S

*Methyl propyl* disulfide-d3**	Isotope-Labeled Compounds	Cancer
Methyl propyl disulfide-d₃ is deuterated labeled Nerol (HY-N7063). Nerol is a constituent of neroli oil. Nerol Nerol triggers mitochondrial dysfunction and induces apoptosis via elevation of Ca ²⁺ and ROS. Antifungal activity .

HY-123068

Captopril disulfide SQ 14551	Angiotensin-converting Enzyme (ACE)	Cardiovascular Disease
Captopril disulfide is a metabolite of Captopril with antihypertensive activity .

HY-P4320

*Cys-Arg-Gly-Asp-Phe-Pro-Ala-Ser-Ser-Cys (Disulfide* bridge:cys1-cys10)**	Integrin	Cancer
Cys-Arg-Gly-Asp-Phe-Pro-Ala-Ser-Ser-Cys (Disulfide bridge:cys1-cys10), a decapeptide containing a cyclic RGD active sequence, is an Integrin αIIbβ3 antagonist that inhibits platelet and Adhesion of proMMP-13 .

HY-140125

*2-Hydroxyethyl disulfide* mono-tosylate**	ADC Linker	Cancer
2-Hydroxyethyl disulfide mono-tosylate is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-W291642

Bis[2-(4-azidosalicylamido)ethyl] disulfide	Biochemical Assay Reagents	Others
Bis[2-(4-azidosalicylamido)ethyl] disulfide is a biochemical reagent.

HY-B0553S

Methazolamide-d6 L584601-d<sub>6sub>	Isotope-Labeled Compounds Carbonic Anhydrase	Inflammation/Immunology
Methazolamide-d₆ is the deuterium labeled Methazolamide. Methazolamide (L584601) is a sulfonamide derivative used as a carbonic anhydrase inhibitor with a Ki of 14 nM for human carbonic anhydrase II. Methazolamide, an intraocular pressure-lowering agent, reduces intraocular pressure elevations associated with glaucoma and other ocular disorders[1][2].

HY-140126

*Bis-Tos-(2-hydroxyethyl disulfide)*	ADC Linker	Cancer
Bis-Tos-(2-hydroxyethyl disulfide) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-15917S2

DL-dithiothreitol-d6 DTT-d<sub>6sub>	Isotope-Labeled Compounds Disulfidptosis	Cancer
DL-dithiothreitol-d₆ is the deuterated form of DL-dithiothreitol. DL-dithiothreitol (DTT) is a strong reductant with anti-disulfidptosis activity. DL-dithiothreitol is oxidized to form a stable six-membered ring with an internal disulfide bond .

HY-157440

AChE/Aβ-IN-3	Amyloid-β Reactive Oxygen Species Cholinesterase (ChE)	Neurological Disease
AChE/Aβ-IN-3 (compound AM5) is a dual inhibitor of AChE and Amyloid-β aggregation with *IC_50<.sub>* values of 1.29 and 4.93 μM, respectively. AChE/Aβ-IN-3 has antioxidant properties that scavenge ROS and restore their normal levels. AChE/Aβ-IN-3 can be used in the study of neurological diseases, such as Alzheimer's disease .

HY-15917S

DL-dithiothreitol-d10 DTT-d<sub>10sub>	Isotope-Labeled Compounds Disulfidptosis	Cancer
DL-dithiothreitol-d₁₀ is the deuterated form of DL-dithiothreitol. DL-dithiothreitol (DTT) is a strong reductant with anti-disulfidptosis activity. When DL-dithiothreitol is oxidized, it forms a stable six-membered ring with an internal disulfide bond .

HY-121883S

Lignoceric acid-d47 Tetracosanoic acid-d<sub>47sub>	Isotope-Labeled Compounds Endogenous Metabolite	Neurological Disease
Lignoceric acid-d₄₇ is the deuterium labeled Lignoceric acid. Lignoceric acid (Tetracosanoic acid) is a 24-carbon saturated (24:0) fatty acid, which is synthesized in the developing brain. Lignoceric acid is also a by-product of lignin production. Lignoceric acid can be used for Zellweger cerebro‐hepato‐renal syndrome and adrenoleukodystrophy research[1][2].

HY-144290

ARN25068	GSK-3 DYRK	Neurological Disease
ARN25068 is a sub-micromolar inhibitor of the three protein kinases, GSK-3β, FYN and DYRK1A to tackle tau hyperphosphorylation .

HY-N7118

Clindamycin hydrochloride monohydrate	Bacterial Antibiotic	Infection Cancer
Clindamycin hydrochloride monohydrate is an oral protein synthesis inhibitory agent that has the ability to suppress the expression of virulence factors in Staphylococcus aureus at sub-inhibitory concentrations (sub-MICs). Clindamycin hydrochloride monohydrate resistance results from enzymatic methylation of the antibiotic binding site in the 50S ribosomal subunit (23S rRNA). Clindamycin hydrochloride monohydrate decreases the production of Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1) or alpha-haemolysin (Hla) .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-Y1177

Diphenyl disulfide Phenyl disulfide	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Diphenyl disulfide is an endogenous metabolite.

HY-B2224

Thiamine disulfide	Infection Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	HIV Endogenous Metabolite
Thiamine disulfide, a vitamin B1 derivative, is an oxidized dimer of Thiamine. Thiamine disulfide is a potent HIV-1 inhibitor. Thiamine disulfide significantly depresses HIV-1 transactivator (Tat) activity .

HY-W009516

Dibenzyl disulfide	Structural Classification Natural Products Classification of Application Fields Petiveriaceae Source classification Metabolic Disease Plants Endogenous metabolite Disease Research Fields Petiveria alliacea	Endogenous Metabolite
Dibenzyl disulfide is an endogenous metabolite.

HY-W015635

Diallyl disulfide 1 Publications Verification	Structural Classification Natural Products Liliaceae Classification of Application Fields Source classification Plants Disease Research Fields A．Sativam L. var．Viviparum Regel Cancer	Others
Diallyl disulfide, an active compound in garlic oil, is an orally active human squalene monooxygenase inhibitor with an IC₅₀ of 400 μM for squalene epoxidation. Diallyl disulfide exhibits obvious anti-inflammatory, anti-oxidative, antidepressant and anti-tumor activities .

HY-125833

Alpha-Naphthoflavone 5+ Cited Publications	Flavonoids Flavones Source classification Indigofera heterantha Wall. ex Brand. Plants Compositae Disease Research Fields Cancer	Cytochrome P450 Aryl Hydrocarbon Receptor Apoptosis
Alpha-Naphthoflavone is an orally active flavonoid that is a potent, competitive inhibitor of aromatase< b>aromatase. < b > IC < sub > 50 < / sub > < / b > and < b > K < sub > I < / sub > < / b > value were 0.5 and 0.2 microns. Alpha-Naphthoflavone can inhibit cell proliferation and induce apoptosis .

HY-N7436

Methyl propyl disulfide	Structural Classification Natural Products Liliaceae Classification of Application Fields Source classification Allium cepa L. Plants Disease Research Fields Cancer	Others
Methyl propyl disulfide is an volatile sulfur-containing compound produced in garlic and onions with anticaner effect .

HY-W009516R

*Dibenzyl disulfide* (Standard)**	Structural Classification Natural Products Petiveriaceae Source classification Plants Endogenous metabolite Petiveria alliacea	Endogenous Metabolite
Dibenzyl disulfide (Standard) is the analytical standard of Dibenzyl disulfide. This product is intended for research and analytical applications. Dibenzyl disulfide is an endogenous metabolite.

HY-B2224R

*Thiamine disulfide* (Standard)**	Structural Classification Natural Products Source classification Endogenous metabolite	HIV Endogenous Metabolite
Thiamine disulfide (Standard) is the analytical standard of Thiamine disulfide. This product is intended for research and analytical applications. Thiamine disulfide, a vitamin B1 derivative, is an oxidized dimer of Thiamine. Thiamine disulfide is a potent HIV-1 inhibitor. Thiamine disulfide significantly depresses HIV-1 transactivator (Tat) activity .

HY-W015635R

*Diallyl disulfide* (Standard)**	Structural Classification Natural Products Liliaceae Source classification Plants A．Sativam L. var．Viviparum Regel	Others
Diallyl disulfide (Standard) is the analytical standard of Diallyl disulfide. This product is intended for research and analytical applications. Diallyl disulfide, an active compound in garlic oil, is an orally active human squalene monooxygenase inhibitor with an IC₅₀ of 400 μM for squalene epoxidation. Diallyl disulfide exhibits obvious anti-inflammatory, anti-oxidative, antidepressant and anti-tumor activities .

HY-N11799

Neochilenin 3-O-Methylquercetin 4′-O-glucoside	Structural Classification Flavonoids Source classification Plants Compositae Other Flavonoids	Others
Neochilenin (3-O-Methylquercetin 4 '-O-glucoside) is a glycoside of 3-O-methylquercetin, which can be isolated from the sub-family Cereoideae (Cactaceae). .

HY-W009708

Bis(2-methyl-3-furyl)disulfide	Natural Products Microorganisms Classification of Application Fields Animals Source classification Other Diseases Disease Research Fields	Others
Bis(2-methyl-3-furyl)disulfide, compound (2), is intended to provide a flavoring compound to enhance a natural feeling, a fresh feeling and a milk-rich feeling of a milk-related product .

HY-W011474

Geranylgeraniol	Structural Classification Natural Products Microorganisms	NF-κB
Geranylgeraniol is an orally acitve vitamin K₂ sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model .

HY-N9600

Dotriacontane	Structural Classification Natural Products other families Palaquium wax Source classification Plants	Others
Dotriacontane is an alkane substance that can be absorbed and metabolized by photosynthetic organisms. It can be labeled with ¹⁴C and used for carbon tracing .

HY-P2274

Argifin	Infection Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields	Parasite
Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms, with IC₅₀s of 0.025 μM, 6.4 μM , 1.1 μM and 4.5 μM for SmChiA (Serratia marcescens chitinaese A), SmChiB, Aspergillus fumigatus chitinase B1 and human chitotriosidase, respectively .

HY-N9600R

Dotriacontane (Standard)	Structural Classification Natural Products other families Palaquium wax Source classification Plants	Others
Dotriacontane (Standard) is the analytical standard of Dotriacontane. This product is intended for research and analytical applications. Dotriacontane is an alkane substance that can be absorbed and metabolized by photosynthetic organisms. It can be labeled with 14C and used for carbon tracing .

HY-N10192

Aculene D	Infection Microorganisms Classification of Application Fields Terpenoids Sesquiterpenes Source classification Disease Research Fields	Endogenous Metabolite Bacterial
Aculene D, a fungal metabolite, shows quorum sensing (QS) inhibitory activity against Chromobacterium violaceum CV026, and could significantly reduce violacein production in N-hexanoyl-l-homoserine lactone (C6-HSL) induced C. violaceum CV026 cultures at sub-inhibitory concentrations .

HY-W011474R

Geranylgeraniol (Standard)	Structural Classification Natural Products Microorganisms	NF-κB
Geranylgeraniol (Standard) is the analytical standard of Geranylgeraniol. This product is intended for research and analytical applications. Geranylgeraniol is an orally acitve vitamin K2 sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model [4].

HY-130778

N,N'-Diacetylchitobiose	Structural Classification Microorganisms Animals Classification of Application Fields Source classification Other Diseases Disease Research Fields Saccharides	Endogenous Metabolite
N,N'-Diacetylchitobiose is a dimer of β(1,4) linked N-acetyl-D glucosamine. N,N'-Diacetylchitobiose is the hydrolysate of chitin and can be used as alternative carbon source by E. coli .

HY-N0662

Amentoflavone 5+ Cited Publications Didemethyl-ginkgetin	Structural Classification Flavonoids Classification of Application Fields Source classification Phenols Polyphenols Selaginellaceae Plants Biflavones Selaginella tamariscina (P. Beauv.) Spring Disease Research Fields Cancer	Reactive Oxygen Species Apoptosis Bacterial Fungal RSV GABA Receptor
Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active GABA(A) negative modulator. Amentoflavone also shows anti-inflammatory, antioxidative, anti-viral, anti-tumor, anti-radiation, anti-fungal, antibacterial activity. Amentoflavone induces apoptosis and cell cycle arrest at sub-G1 phase .

HY-W013636

2-Ketoglutaric acid 3 Publications Verification Alpha-Ketoglutaric acid	Structural Classification Classification of Application Fields Anti-aging Source classification Endocrine diseases Endogenous metabolite Immune System Disorder Microorganisms Ketones, Aldehydes, Acids Disease markers Other Diseases Nervous System Disorder Disease Research Fields	Tyrosinase Endogenous Metabolite
2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC₅₀=15 mM) .

HY-W013636A

2-Ketoglutaric acid Sodium 3 Publications Verification Alpha-Ketoglutaric acid Sodium	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Tyrosinase Endogenous Metabolite
2-Ketoglutaric acid Sodium (Alpha-Ketoglutaric acid Sodium) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid Sodium also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid Sodium is a reversible inhibitor of tyrosinase (IC₅₀=15 mM) .

HY-W013636B

Calcium 2-oxoglutarate 3 Publications Verification	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Tyrosinase Endogenous Metabolite
Calcium 2-oxoglutarate is an intermediate in the production of ATP or GTP in the Krebs cycle. Calcium 2-oxoglutarate also acts as the major carbon skeleton for nitrogen-assimilatory reactions. Calcium 2-oxoglutarate is a reversible inhibitor of tyrosinase (IC₅₀=15 mM) .

HY-P99294

Ganitumab AMG 479; Human Anti-IGF1R Recombinant Antibody	Classification of Application Fields Disease Research Fields Cancer	IGF-1R
Ganitumab (AMG 479) is a recombinant human monoclonal antibody to the human type 1 insulin-like growth factor receptor (IGF1R). Ganitumab recognizes murine IGF1R with sub-nanomolar affinity (K_D=0.22 nM) and inhibits the interaction of murine IGF1R with IGF1 and IGF2. Ganitumab can be used in research of cancer .

HY-N0662R

Amentoflavone (Standard)	Structural Classification Flavonoids Source classification Phenols Polyphenols Selaginellaceae Plants Biflavones Selaginella tamariscina (P. Beauv.) Spring	Reactive Oxygen Species Apoptosis Bacterial Fungal RSV GABA Receptor
Amentoflavone (Standard) is the analytical standard of Amentoflavone. This product is intended for research and analytical applications. Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active GABA(A) negative modulator. Amentoflavone also shows anti-inflammatory, antioxidative, anti-viral, anti-tumor, anti-radiation, anti-fungal, antibacterial activity. Amentoflavone induces apoptosis and cell cycle arrest at sub-G1 phase .

HY-W013636R

2-Ketoglutaric acid (standard) 3 Publications Verification	Structural Classification Immune System Disorder Microorganisms Ketones, Aldehydes, Acids Source classification Disease markers Endocrine diseases Nervous System Disorder Endogenous metabolite	Tyrosinase Endogenous Metabolite
2-Ketoglutaric acid (Standard) is the analytical standard of 2-Ketoglutaric acid. This product is intended for research and analytical applications. 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC₅₀=15 mM) .

HY-142101

3,4-Didehydroglabridin	Structural Classification Natural Products Leguminosae Source classification Plants Glycyrrhiza uralensis Fisch.	Others
3,4-Didehydroglabridin is a natural product that can be found in licorice. 3,4-Didehydroglabridin exhibits protective activities against carbon tetrachloride-induced HepG2 cells injury. 3,4-Didehydroglabridin has the potential for the research of liver injury .

HY-W751835

Baloxavir-d4 Maximum Cited Publications 30 Publications Verification Baloxavir acid-d<sub>4sub>; S-033447-d<sub>4sub>	Classification of Application Fields Disease Research Fields Cancer	Isotope-Labeled Compounds
Baloxavir-d₄ (Baloxavir acid-d₄; S-033447-d₄) is the deuterium-labeled Baloxavir (HY-109025A). Baloxavir-d₄ (Baloxavir-d₄ acid), derived from the proagent Baloxavir-d₄ marboxil, is a first-in-class, potent and selective cap-dependent endonuclease (CEN) inhibitor within the polymerase PA subunit of influenza A and B viruses. Baloxavir-d₄ inhibits viral RNA transcription and replication and has potently antiviral activity .

HY-B1529A

Citric acid triammonium 20+ Cited Publications Triammonium citrate	Classification of Application Fields Disease Research Fields Cancer	Endogenous Metabolite Apoptosis Biochemical Assay Reagents
Citric acid triammonium (Triammonium citrate) is formed by Citric acid (HY-N1428) reacting with ammonia in a molar ratio of 1:3. Citric acid triammonium can be used as the carbon source to prepare carbon quantum dots (CDs). Citric acid triammonium with higher nitrogen components might promote the nitrogen-based functional groups in CDs, leading to a more efficient emission-color tunability .

HY-B0910

Pyrithioxin Pyritinol; Pyridoxine disulfide; Vitamin B6 disulfide	Structural Classification Natural Products Source classification Endogenous metabolite	Endogenous Metabolite
Pyrithioxin is a neurodynamic compound, combined with a short period of hyperventilation (HV) was applied in cerebral infarct patients with Hemiplegia.

HY-B0910A

Pyrithioxin dihydrochloride Pyritinol dihydrochloride; Pyridoxine disulfide dihydrochloride; Vitamin B6 disulfide dihydrochloride	Structural Classification Natural Products Neurological Disease Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Pyrithioxin dihydrochloride is a neurodynamic compound, combined with a short period of hyperventilation (HV) was applied in cerebral infarct patients with Hemiplegia.

HY-W004297

1-Nonadecanol	Natural Products other families Classification of Application Fields Source classification Other Diseases Plants Disease Research Fields	Others
1-Nonadecanol is one of the compositions of supercritical carbon dioxide (SC-CO₂) essential oil of Heracleum thomsonii. 1-Nonadecanol is also an important aroma compound in Neotinea ustulata .

HY-B0504S

Creatinine-d3 3 Publications Verification NSC13123-d<sub>3sub>	Classification of Application Fields Metabolic Disease Disease Research Fields	Endogenous Metabolite
Creatinine-d₃ is a deuterium labeled Creatinine. Creatinine is a break-down product of creatine phosphate in muscle[1].

HY-W004297R

1-Nonadecanol (Standard)	Structural Classification Natural Products other families Source classification Plants	Others
1-Nonadecanol (Standard) is the analytical standard of 1-Nonadecanol. This product is intended for research and analytical applications. 1-Nonadecanol is one of the compositions of supercritical carbon dioxide (SC-CO2) essential oil of Heracleum thomsonii. 1-Nonadecanol is also an important aroma compound in Neotinea ustulata .

HY-W008343

1,3-Dimethyluracil	Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
1,3-Dimethyluracil is a pyrimidone derives from a uracil. 1,3-Dimethyluracil found occasionally in human urine. 1,3-Dimethyluracil shows inhibition activity against hCA I and hCA II (human carbonic anhydrase) with K_i of 316.2 μM and 166.4 μM, respectively .

HY-B1028

Pantethine 1 Publications Verification D-Pantethine; LBF disulfide	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite SARS-CoV
Pantethine is an orally active lipid-lowering agent. Pantethine has anti-tumor, anti-inflammatory and anti-SARS-COV virus activities. Pantethine is also a neuroprotective agent. Pantethine can be used in the study of Alzheimer's disease, Parkinson's disease, major depression, systemic sclerosis and pantothenate kinase-related neurodegeneration .

HY-W004283

Pentadecanoic acid	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Pentadecylic acid is a saturated fatty acid with a 15-carbon backbone.

HY-W004286

Methyl laurate	Natural Products Microorganisms Classification of Application Fields Labiatae Source classification Other Diseases Plants Disease Research Fields Medicago truncatula Gaertn.	Others
Methyl laurate, a 12-carbon saturated fatty acid, is an esterified version of lauric acid .

HY-124422

Pentacosanoic acid	other families Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Plants Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Pentacosanoic acid is a 25-carbon long-chain saturated fatty acid. Pentacosanoic is a conjugate acid of a pentacosanoate .

HY-N8268

Nordeoxycholic acid 3α,12α-Dihydroxynorcholanic acid	Animals Source classification	Others
Nordeoxycholic acid is a 23-carbon bile acid. Nordeoxycholic acid is a norcholic acid metabolite and a steroid human metabolite .

HY-N9043

Tasumatrol L	Structural Classification Ketones, Aldehydes, Acids Source classification Taxaceae Taxus sumatrana (Miq.) de Laub. Plants	Others
Tasumatrol L (compound 5) is a 21-carbon taxane ester that can be found in Taxus sumatrana .

HY-W004261

Nonadecanoic acid	Structural Classification Microorganisms other families Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Plants Disease Research Fields	Endogenous Metabolite
Nonadecanoic acid is a 19-carbon long saturated fatty acid. Nonadecanoic acid is the major constituent of the substance secreted by Rhinotermes marginalis to defence .

HY-N6811

1-Octacosanol	Natural Products Classification of Application Fields Euphorbia boetica Source classification Other Diseases Euphorbiaceae Plants Disease Research Fields	Others
1-Octacosanol is a straight-chain aliphatic 28-carbon fatty alcohol with well-known anti-fatigue function .

HY-128030

Makisterone A	Classification of Application Fields Source classification Chenopodium quinoa Willd. Plants Disease Research Fields Endocrinology Steroids Chenopodiaceae	Others
Makisterone A, a 28-carbon moulting hormone, has been identified as the major free pupal ecdysteroid in the honey bee, Apis mellifera .

HY-113004

3-Hydroxyvaleric acid	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease markers Metabolic Disease Endocrine diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
3-Hydroxyvaleric acid is a 5-carbon ketone body. 3-Hydroxyvaleric acid is anaplerotic, meaning it can refill the pool of TCA cycle intermediates.

HY-124141

Myristelaidic acid trans-9-Tetradecenoic acid	Classification of Application Fields Animals Ketones, Aldehydes, Acids Source classification Metabolic Disease Disease Research Fields	Endogenous Metabolite
Myristelaidic acid (trans-9-Tetradecenoic acid), a 14-carbon trans fatty acid, is the trans isomer of Myristoleic acid. Myristelaidic acid is found in most animal fats .

HY-W004286R

Methyl laurate (Standard) Methyl dodecanoate (Standard)	Structural Classification Natural Products Classification of Application Fields Labiatae Source classification Other Diseases Plants Disease Research Fields Medicago truncatula Gaertn.	Others
Methyl laurate (Standard) is the analytical standard of Methyl laurate. This product is intended for research and analytical applications. Methyl laurate, a 12-carbon saturated fatty acid, is an esterified version of lauric acid .

HY-N10204

Rostratin B	Alkaloids Microorganisms Pyrrole Alkaloids Classification of Application Fields Source classification Disease Research Fields Cancer	Endogenous Metabolite
Rostratin B, a cytotoxic disulfide, shows in vitro cytotoxicity against human colon carcinoma (HCT-116) with IC₅₀ of 1.9 μg/mL .

HY-126050

(R)-Pantetheine Pantetheine	Structural Classification Natural Products Human Gut Microbiota Metabolites Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
(R)-Pantetheine is the biosynthetic precursor to CoA. (R)-Pantetheine and its corresponding disulfide pantethine, play a key role in metabolism as a building block of coenzyme A (CoA) .

HY-N10205

Rostratin C	Alkaloids Microorganisms Pyrrole Alkaloids Classification of Application Fields Source classification Disease Research Fields Cancer	Endogenous Metabolite
Rostratin C, a cytotoxic disulfide, shows in vitro cytotoxicity against human colon carcinoma (HCT-116) with IC₅₀ value of 0.76μg /mL .

HY-N7399

Dipalmitin	Structural Classification Natural Products Araceae Source classification Plants Sauromatum giganteum (Engler) Cusimano & Hetterscheid	Others
Dipalmitin is an active product that can be extracted from? root tuber of Typhonium giganteum Engl. Dipalmitin is a diacylglycerol that contains the saturated 16-carbon fatty acid Palmitic acid (HY-N0830) at two positions .

Cat. No.	Product Name	Chemical Structure

HY-W004282S

Undecanoic acid-d21
Undecanoic acid-d₂₁ is the deuterium labeled Undecanoic acid. Undecanoic acid (Undecanoate) is a monocarboxylic acid with antimycotic property, which inhibits the production of exocellular keratinase, lipase and the biosynthesis of several phospholipids in T. rubrum[1].

HY-100085S

21-Desacetyldeflazacort-d5
21-Desacetyldeflazacort-d₅ is the deuterium labeled 21-Desacetyldeflazacort[1].

HY-W012351S

Tripropyl phosphate-d21
Tripropyl phosphate-d₂₁ is the deuterium labeled Tripropyl phosphate[1].

HY-Y1213S

Carbon-13C
Carbon- ¹³C is the ¹³C labeled Carbon[1].

HY-151131S

Tri-iso-propyl-d21-phosphine carbon disulfide complex-d21
Tri-iso-propyl-d₂₁-phosphine carbon disulfide complex-d₂₁ is the deuterium labeled Tri-iso-propyl-d21-phosphine carbon disulfide complex[1].

HY-W142921S

*Allyl methyl disulfide-d3*
Allyl methyl disulfide-d₃ is deuterated labeled (E)-Oct-2-enal.

HY-W654319

Tri-p-tolyl phosphate-d21
Tri-p-tolyl phosphate-d21 is the deuterium labeled Tri-p-tolyl phosphate .

HY-10844S1

Pretomanid-d5
Pretomanid-d₅ is deuterated labeled Pretomanid (HY-10844). Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 μg/mL.

HY-N7436S

*Methyl propyl* disulfide-d3**
Methyl propyl disulfide-d₃ is deuterated labeled Nerol (HY-N7063). Nerol is a constituent of neroli oil. Nerol Nerol triggers mitochondrial dysfunction and induces apoptosis via elevation of Ca ²⁺ and ROS. Antifungal activity .

HY-B0553S

Methazolamide-d6
Methazolamide-d₆ is the deuterium labeled Methazolamide. Methazolamide (L584601) is a sulfonamide derivative used as a carbonic anhydrase inhibitor with a Ki of 14 nM for human carbonic anhydrase II. Methazolamide, an intraocular pressure-lowering agent, reduces intraocular pressure elevations associated with glaucoma and other ocular disorders[1][2].

HY-15917S2

DL-dithiothreitol-d6
DL-dithiothreitol-d₆ is the deuterated form of DL-dithiothreitol. DL-dithiothreitol (DTT) is a strong reductant with anti-disulfidptosis activity. DL-dithiothreitol is oxidized to form a stable six-membered ring with an internal disulfide bond .

HY-15917S

DL-dithiothreitol-d10
DL-dithiothreitol-d₁₀ is the deuterated form of DL-dithiothreitol. DL-dithiothreitol (DTT) is a strong reductant with anti-disulfidptosis activity. When DL-dithiothreitol is oxidized, it forms a stable six-membered ring with an internal disulfide bond .

HY-121883S

Lignoceric acid-d47
Lignoceric acid-d₄₇ is the deuterium labeled Lignoceric acid. Lignoceric acid (Tetracosanoic acid) is a 24-carbon saturated (24:0) fatty acid, which is synthesized in the developing brain. Lignoceric acid is also a by-product of lignin production. Lignoceric acid can be used for Zellweger cerebro‐hepato‐renal syndrome and adrenoleukodystrophy research[1][2].

HY-121883S1

Lignoceric acid-d3
Lignoceric acid-d₃ is the deuterium labeled Lignoceric acid[1]. Lignoceric acid (Tetracosanoic acid) is a 24-carbon saturated (24:0) fatty acid, which is synthesized in the developing brain. Lignoceric acid is also a by-product of lignin production. Lignoceric acid can be used for Zellweger cerebro‐hepato‐renal syndrome and adrenoleukodystrophy research[2][3].

HY-Y1718S

Tridecanoic acid-d2
Tridecanoic acid-d₂ is the deuterium labeled Tridecanoic acid. Tridecanoic acid (N-Tridecanoic acid), a 13-carbon medium-chain saturated fatty acid, can serve as an antipersister and antibiofilm agent that may be applied to research bacterial infections. Tridecanoic acid inhibits Escherichia coli persistence and biofilm formation[1].

HY-Y1718S1

Tridecanoic acid-d25
Tridecanoic acid-d₂₅ is the deuterium labeled Tridecanoic acid. Tridecanoic acid (N-Tridecanoic acid), a 13-carbon medium-chain saturated fatty acid, can serve as an antipersister and antibiofilm agent that may be applied to research bacterial infections. Tridecanoic acid inhibits Escherichia coli persistence and biofilm formation[1].

HY-Y1718S2

Tridecanoic acid-d9
Tridecanoic acid-d₉ is the deuterium labeled Tridecanoic acid. Tridecanoic acid (N-Tridecanoic acid), a 13-carbon medium-chain saturated fatty acid, can serve as an antipersister and antibiofilm agent that may be applied to research bacterial infections. Tridecanoic acid inhibits Escherichia coli persistence and biofilm formation[1].

HY-B0588S

Brinzolamide-d5
Brinzolamide-d₅ is the deuterium labeled Brinzolamide. Brinzolamide (AL 4862) is a potent carbonic anhydrase II inhibitor with IC50 of 3.19 nM.

HY-B0400S4

D-Sorbitol-d2
D-Sorbitol-d₂ is the deuterium labeled D-Sorbitol. D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and diet

HY-B0400S10

D-Sorbitol-d4
D-Sorbitol-d₄ is the deuterium labeled D-Sorbitol. D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and diet

HY-B0400S

D-Sorbitol-d8
D-Sorbitol-d₈ is the deuterium labeled D-Sorbitol. D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and dietary supplement[1].

HY-15917S1

DL-dithiothreitol-d10-1
DL-dithiothreitol-d₁₀-1 is the deuterated form of DL-dithiothreitol. DL-dithiothreitol (DTT) is a strong reductant with anti-disulfidptosis activity. DL-dithiothreitol is oxidized to form a stable six-membered ring with an internal disulfide bond .

HY-A0143S

Dihomo-γ-linolenic acid-d6
Dihomo-γ-linolenic acid-d₆ (DGLA-d₆) is the deuterium labeled Dihomo-γ-linolenic acid. Dihomo-γ-linolenic acid (all-cis-8,11,14-Eicosatrienoic acid) is a 20-carbon ω-6 fatty acid, with anti-inflammatory and anti-proliferative activities. Dihomo-γ-linolenic acid attenuates atherosclerosis in the apolipoprotein E deficient mouse model system[1][2][3].

HY-121883S4

Lignoceric acid-d4-2
Lignoceric acid-d₄-2 is the deuterium labeled Lignoceric acid. Lignoceric acid (Tetracosanoic acid) is a 24-carbon saturated (24:0) fatty acid, which is synthesized in the developing brain. Lignoceric acid is also a by-product of lignin production. Lignoceric acid can be used for Zellweger cerebro‐hepato‐renal syndrome and adrenoleukodystrophy research[1][2].

HY-B0109AS

Dorzolamide-d3 hydrochloride
Dorzolamide-d₃ hydrochloride is deuterated labeled Dorzolamide hydrochloride (HY-B0109A). Dorzolamide (L671152) hydrochloride is a potent carbonic anhydrase II inhibitor, with IC₅₀ values of 0.18 nM and 600 nM for red blood cell CA-II and CA-I respectively. Dorzolamide possesses anti-tumor activity .

HY-W014612S

Eugenol acetate-d3
Eugenol acetate-d₃ is deuterated labeled Decyl aldehyde (HY-W012570). Decyl aldehyde is a simple ten-carbon aldehyde. Decyl aldehyde is a bacterial luciferase substrate.

HY-B0400S7

D-Sorbitol-d1-2
D-Sorbitol-d-2 is the deuterium labeled D-Sorbitol. D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and di

HY-W192474S

1-(Furan-2-yl)ethane-1-thiol-d3
1-(Furan-2-yl)ethane-1-thiol-d₃ is deuterated labeled Allyl methyl disulfide.

HY-B0400S8

D-Sorbitol-d2-1
D-Sorbitol-d₂-1 is the deuterium labeled D-Sorbitol. D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and di

HY-B0400S9

D-Sorbitol-d2-2
D-Sorbitol-d₂-2 is the deuterium labeled D-Sorbitol. D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and di

HY-Y0682S

EDTA-d12

EDTA-d₁₂ is the deuterium labeled Ethylenediaminetetraacetic acid[1]. Ethylenediaminetetraacetic acid (EDTA) is a metal chelators (binds to metal divalent and trivalent cations including calcium), which shows activities of anticoagulant and anti-hypercalcemic. Ethylenediaminetetraacetic acid decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid can also decrease the formation of disulfide bonds[2][3][4].

HY-Y0682S1

Ethylenediaminetetraacetic acid-d16

Ethylenediaminetetraacetic acid-d₁₆ is the deuterium labeled Ethylenediaminetetraacetic acid[1]. Ethylenediaminetetraacetic acid (EDTA) is a metal chelators (binds to metal divalent and trivalent cations including calcium), which shows activities of anticoagulant and anti-hypercalcemic. Ethylenediaminetetraacetic acid decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid can also decrease the formation of disulfide bonds[2][3][4].

HY-W015913S1

Sodium 2-oxopropanoate-d3
Sodium 2-oxopropanoate-d₃ is the deuterium labeled Sodium 2-oxopropanoate[1]. Sodium 2-oxopropanoate (Sodium pyruvate), a three-carbon metabolite of Glucose, is a compound produced in the glycolytic pathway. Sodium 2-oxopropanoate is a free radical scavenger that can scavenge ROS[2][3].

HY-B1028S

Pantethine-15N2

Pantethine- ¹⁵N₂ is the ¹⁵N₂ labeled Pantethine. Pantethine is an orally active lipid-lowering agent. Pantethine has anti-tumor, anti-inflammatory and anti-SARS-COV virus activities. Pantethine is also a neuroprotective agent. Pantethine can be used in the study of Alzheimer's disease, Parkinson's disease, major depression, systemic sclerosis and pantothenate kinase-related neurodegeneration .

HY-B0400S16

D-Sorbitol-13C6
D-Sorbitol- ¹³C₆ is the ¹³C labeled D-Sorbitol[1]. D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and dietary supplement[2].

HY-B0588AS

Brinzolamide-d5 hydrochloride

Brinzolamide-d₅ (hydrochloride) is the deuterium labeled Brinzolamide hydrochloride[1]. Brinzolamide (AL-4862) hydrochloride is a selective carbonic anhydrase II inhibitor with an IC50 value of 3.2 nM. Brinzolamide hydrochloride reduces intraocular pressure (IOP) by inhibiting ciliary CA-II and decreasing atrial fluid secretion. Brinzolamide hydrochloride can be used in glaucoma disease research[2][3].

HY-N7057S

Nonanoic acid-d17
Nonanoic acid-d₁₇ is the deuterium labeled Nonanoic acid. Nonanoic acid is a naturally-occurring saturated fatty acid with nine carbon atoms. Nonanoic acid significantly reduces bacterial translocation, enhances antibacterial activity, and remarkably increases the secretion of porcine β-defensins 1 (pBD-1) and pBD-2[1].

HY-N7057S1

Nonanoic acid-d3
Nonanoic acid-d₃ is the deuterium labeled Nonanoic acid. Nonanoic acid is a naturally-occurring saturated fatty acid with nine carbon atoms. Nonanoic acid significantly reduces bacterial translocation, enhances antibacterial activity, and remarkably increases the secretion of porcine β-defensins 1 (pBD-1) and pBD-2[1].

HY-N7057S2

Nonanoic acid-d4
Nonanoic acid-d₄ is the deuterium labeled Nonanoic acid. Nonanoic acid is a naturally-occurring saturated fatty acid with nine carbon atoms. Nonanoic acid significantly reduces bacterial translocation, enhances antibacterial activity, and remarkably increases the secretion of porcine β-defensins 1 (pBD-1) and pBD-2[1].

HY-N0390S3

L-Glutamine-13C5,15N2,d5
L-Glutamine- ¹³C₅, ¹⁵N₂,d₅ is the deuterium, ¹³C-, and 15-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells[1][2].

HY-N0390S7

L-Glutamine-15N2,d5
L-Glutamine- ¹⁵N₂,d₅ is the deuterium and ¹⁵N-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells[1][2].

HY-B1455S

Clindamycin-d3 hydrochloride

Clindamycin-d₃ (hydrochloride) is the deuterium labeled Clindamycin. Clindamycin is an orally active and broad-spectrum bacteriostatic lincosamide antibiotic. Clindamycin can inhibit bacterial protein synthesis, possessing the ability to suppress the expression of virulence factors in Staphylococcus aureus at sub-inhibitory concentrations (sub-MICs). Clindamycin resistance results from enzymatic methylation of the antibiotic binding site in the 50S ribosomal subunit (23S rRNA). Clindamycin decreases the production of Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1) or alpha-haemolysin (Hla). Clindamycin also can be used for researching malaria[1][2].

HY-N0390S2

L-Glutamine-d5
L-Glutamine-d₅ is the deuterium labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells[1][2].

HY-N0390S6

L-Glutamine-13C5,15N2
L-Glutamine- ¹³C₅, ¹⁵N₂ is the ¹³C- and ¹⁵N-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells[1][2].

HY-W015913S

Sodium 2-oxopropanoate-13C3
Sodium 2-oxopropanoate- ¹³C₃ is the ¹³C-labeled Sodium 2-oxopropanoate. Sodium 2-oxopropanoate (Sodium pyruvate), a three-carbon metabolite of Glucose, is a compound produced in the glycolytic pathway. Sodium 2-oxopropanoate is a free radical scavenger that can scavenge ROS[1][2].

HY-B1455S1

Clindamycin-13C,d3

Clindamycin- ¹³C,d₃ is the ¹³C- and deuterium labeled Clindamycin. Clindamycin is an orally active and broad-spectrum bacteriostatic lincosamide antibiotic. Clindamycin can inhibit bacterial protein synthesis, possessing the ability to suppress the expression of virulence factors in Staphylococcus aureus at sub-inhibitory concentrations (sub-MICs). Clindamycin resistance results from enzymatic methylation of the antibiotic binding site in the 50S ribosomal subunit (23S rRNA). Clindamycin decreases the production of Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1) or alpha-haemolysin (Hla). Clindamycin also can be used for researching malaria[1][2][3].

HY-B0122S

Topiramate-13C6

Topiramate-13C6 (McN 4853-13C6) is the ¹³C labeled isotope of Topiramate (HY-B0122). Topiramate (McN 4853) is a broad-spectrum antiepileptic agent. Topiramate is a GluR5 receptor antagonist. Topiramate produces its antiepileptic effects through enhancement of GABAergic activity, inhibition of kainate/AMPA receptors, inhibition of voltage-sensitive sodium and calcium channels, increases in potassium conductance, and inhibition of carbonic anhydrase .

HY-W343538S

2-Methyl-3-(methyldisulfanyl)furan-d3
2-Methyl-3-(methyldisulfanyl)furan-d₃ is deuterated labeled 5-Octyldihydrofuran-2(3H)-one.

HY-W013636S1

2-Ketoglutaric acid-d4
2-Ketoglutaric acid-d₄ is the deuterium labeled 2-Ketoglutaric acid[1]. 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC50=15 mM)[2].

HY-N0390S1

L-Glutamine-13C5 1 Publications Verification
L-Glutamine- ¹³C₅ is the ¹³C-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells[1][2].

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