Search Result
Results for "
Isotopes
" in MedChemExpress (MCE) Product Catalog:
1754
Inhibitors & Agonists
2
Biochemical Assay Reagents
1734
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-159046S
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- HY-B2221S2
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Isotope-Labeled Compounds
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Others
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U-13C Cellulose high DP from wheat is the cellulose (HY-B2221) isolated from wheat, that is consist of abundant glucose and all the carbon atoms are labeled with isotope 13C .
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- HY-163080S
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77Se
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Isotope-Labeled Compounds
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Others
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Selenium-77 (77Se) is a stable (non-radioactive) isotope of Selenium. Selenium-77 is both naturally occurring and produced by fission.
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- HY-Y1298S
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Acetoacetate methyl ester-13C4; Methyl 3-oxobutanoate-13C4; Methyl acetoacetate-13C4
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Endogenous Metabolite
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Others
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Methyl acetylacetate- 13C4 is an isotopically labeled compound. Methyl acetylacetate- 13C4 can be used for various biochemical studies[1].
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- HY-100807S2
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- HY-B1449S11
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- HY-W751961
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- HY-W104379S
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- HY-W269700S
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L-Isoleucyl-L-leucine-13C6,15N
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Isotope-Labeled Compounds
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Metabolic Disease
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Ile-(Leu-13C6,15N)-OH (TFA) is 13C- and 15N-labeled L-Isoleucyl-L-leucine (HY-W269700). L-Isoleucyl-L-leucine has a role as a metabolite and can be used to inhibit movement-induced muscle damage and muscle defective condition.
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- HY-W753671
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- HY-W779009
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Bacterial
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Others
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[1-13Cglc]Lactose monohydrate is an isotopic labeling drug .
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![[1-13Cglc]Lactose monohydrate](//file.medchemexpress.eu/product_pic/hy-w779009.gif)
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- HY-N2024AS2
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- HY-W750599
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- HY-N2024AS1
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- HY-B1941S1
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- HY-B0256S1
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BW 57-322-13C4
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Isotope-Labeled Compounds
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Others
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Azathioprine-13C4 (BW 57-322-13C4) is the 13C labeled Azathioprine (HY-B0256). Azathioprine (BW 57-322) is an orally active immunosuppressive agent. Azathioprine can be converted in vivo to the active metabolite 6-mercaptopurine (6-MP). Azathioprine has myelosuppressive effects and induces apoptosis .
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- HY-N0086S1
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6-Methyladenosine-sup>13C; N-Methyladenosine-sup>13C
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Isotope-Labeled Compounds
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Others
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N6-Methyladenosine- 13C is the 13C labeled isotope of N6-Methyladenosine .
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- HY-W585982S
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- HY-W654023
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- HY-W017401S
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1,2-Benzothiazol-3-one-13C5
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Isotope-Labeled Compounds
Bacterial
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Others
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Benzisothiazolinone-13C5 (1,2-Benzothiazol-3-one-13C5) is a 13C-labeled Benzisothiazolinone. Benzisothiazolinone is widely used as an antiseptic and antibacterial agent .
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- HY-B0892S5
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- HY-147338S1
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5-Methyl-CTP-15N2,13C trisodium
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DNA/RNA Synthesis
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Others
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5-Methylcytidine 5′-triphosphate- 15N2, 13C (5-Methyl-CTP- 15N2, 13C) trisodium is the 15N and 13C labled 5-Methylcytidine 5′-triphosphate (HY-147338). 5-Methylcytidine 5′-triphosphate is a modified nucleoside triphosphate .
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- HY-W778154
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- HY-W778148
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- HY-W017049S
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- HY-W754811
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- HY-163992S
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- HY-163993S
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- HY-159191S
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- HY-W653989
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- HY-W654120
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- HY-W093399S
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Isotope-Labeled Compounds
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Others
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Ammonium bicarbonate-15N is the 15N labeled isotope of Ammonium bicarbonate,AR,99% (HY-W093399). Ammonium bicarbonate is a bioactive chemical .
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- HY-W243408S
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- HY-W770278
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- HY-159192S
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Isotope-Labeled Compounds
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Others
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SADDNIKTPAE(Arg- 13C6, 15N4)LLGPLPPSADDNLKT (TFA) is the 13C and 15N labeled isotope of SADDNIKTPAE-LLGPLPPSADDNLKT (TFA) .
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- HY-W654078
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BPAF-13C12; 4,4'-(Perfluoropropane-2,2-diyl)diphenol-13C12
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Isotope-Labeled Compounds
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Others
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Bisphenol AF- 13C12 is an isotopic label of Bisphenol AF. Bisphenol AF is used in polycarbonate plastic and epoxy resin manufacturing. Bisphenol AF can significantly increase intracellular ROS levels .
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- HY-W778140
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Isotope-Labeled Compounds
Bacterial
Parasite
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Infection
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Diethyl phosphate- 13C4 (sodium) is the 13C labeled isotope of Diethyl phosphate- 13C4 (sodium)(HY-101417).Diethylphosphate (DEP) is product of metabolism and of environmental degradation of a commonly used insecticide Chlorpyrifos .
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- HY-129960S
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Isotope-Labeled Compounds
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Others
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Selenocystine-77Se2 is a stable isotope labelled amino acid. L-Selenocystine is a diselenide-bridged amino acid. L-Selenocystine is a redox-active selenium compound that has both anti- and pro-oxidant actions.
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- HY-128393S1
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- HY-18260S2
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- HY-W012606
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TMH
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Others
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Others
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1,5,5-Trimethylhydantoin (TMH) is a non-isotopic internal standard (IS) .
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- HY-169241
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- HY-B2130S2
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- HY-W654157
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Bacterial
Antibiotic
Isotope-Labeled Compounds
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Infection
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Dicloxacillin- 13C4 sodium hydrate is the 13C-labeled Dicloxacillin Sodium hydrate (HY-B0977). Radioactive isotopes labeled compounds can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified .
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- HY-W100312S
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Toluene, 2-amino-13C6 hydrochloride
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Isotope-Labeled Compounds
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Others
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o-Toluidine-13C6 hydrochloride (Toluene, 2-amino-13C6 hydrochloride) is the 13C labeled isotope of o-Toluidine hydrochloride (HY-W100312) .
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- HY-W585956
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3,4,4′-Trichlorocarbanilide-13C6
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Isotope-Labeled Compounds
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Others
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Triclocarban-13C6 is the 13C labeled isotope of Triclocarban-13C6 (3,4,4′-Trichlorocarbanilide-13C6) .
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- HY-W768345
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D-Trehalose-13C12; α,α-Trehalose-13C12
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Endogenous Metabolite
Isotope-Labeled Compounds
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Others
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D-(+)-Trehalose-13C12 is a 13C isotope labeled version of D-(+)-Trehalose (HY-N1132). D-(+)-Trehalose,which is widespread, can be used as a food ingredient and pharmaceutical excipient .
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- HY-N6726S1
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Isotope-Labeled Compounds
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Others
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Fumonisin B3-13C34-1 is the isotopic internal standard of Fumonisin B3 (HY-N6726). Fumonisin B3 is a mycotoxin derived from fusarium fungi, a member of fumonisins .
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- HY-114293S
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- HY-W777581
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- HY-W777582
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Isotope-Labeled Compounds
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Others
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4-tert-Octylphenol monoethoxylate-13C6 is the 13C labeled isotope of 4-tert-Octylphenol monoethoxylate-13C6 (HY-W777582) .
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- HY-W010575S
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Isotope-Labeled Compounds
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Others
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(2R)-3-Amino-2-fluoropropanoic acid- 13C3 is a 13C-labeled (2R)-3-Amino-2-fluoropropanoic acid. (2R)-3-Amino-2-fluoropropanoic acid is the catabolism of anticancer agent 5-Fluorouracil[1].
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- HY-159193S
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Isotope-Labeled Compounds
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Others
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DHATS(Leu- 13C6, 15N)PVTIPSAVST(Gly- 13C2, 15N)HTTPLPVTDT (TFA) is the 13C and 15N labeled isotope of DHATS-PVTIPSAVST-HTTPLPVTDT (TFA) .
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- HY-W779800
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- HY-143679S
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Isotope-Labeled Compounds
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Others
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4-(3',6'-Dimethyl-3'-heptyl)phenol diethoxylate-13C6 is the 13C labeled isotope of 4-(3',6'-Dimethyl-3'-heptyl)phenol diethoxylate .
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- HY-W778207
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Isotope-Labeled Compounds
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Others
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2'-Deoxyadenosine- 13C5 (monohydrate) is the 13C labeled isotope of 2'-Deoxyadenosine- 13C5 (monohydrate).2'-Deoxyadenosine monohydrate is a deoxyribonucleoside, a building block in chemical synthesis.2'-Deoxyadenosine monohydrate is a deoxyribonucleoside. A building block in the chemical synthesis.
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- HY-W749012
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Isotope-Labeled Compounds
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Others
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(2,4,6-Trichlorophenoxy)acetic acid-13C6 is the 13C labeled isotope of (2,4,6-Trichlorophenoxy)acetic acid-13C6 (HY-W749012) .
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- HY-101399S
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γ-Glutamylphenylalanine-13C9,15N
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Isotope-Labeled Compounds
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Others
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γ-Glu-(Phe- 13C9, 15N) is the 13C and 15N labeled isotope of γ-Glu-Phe(HY-101399).γ-Glu-Phe or the postenzymatic reaction mixture enhanced the umami intensity of commercial soy sauce and model chicken soup.
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- HY-W778225
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Isotope-Labeled Compounds
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Infection
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Vanillic acid- 13C6 is the 13C labeled isotope of Vanillic acid- 13C6(HY-N0708 ).Vanillic acid is a flavoring agent found in edible plants and fruits, and in the root of angelica. Vanillic acid inhibits NF-κB activation. It has anti-inflammatory and antimicrobial activities.
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- HY-104026BS
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- HY-104026CS
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- HY-159064S
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Isotope-Labeled Compounds
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Others
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DSPSAPVNVT(Val- 13C5, 15)R TFA is the 13C and 15N-labeled DSPSAPVNVT(Val)R. Radioactive isotopes labeled compounds can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified .
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- HY-159065S
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Isotope-Labeled Compounds
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Others
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FIQE(Val- 13C5, 15N)NTTTR TFA is the 13C and 15N-labeled FIQE(Val)NTTTR. Radioactive isotopes labeled compounds can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified .
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- HY-B0389A
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Glucose-13C6; D-(+)-Glucose-13C6; Dextrose-13C6
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Endogenous Metabolite
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Others
Metabolic Disease
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D-Glucose- 13C6 is a stable isotope-labeled counterpart of D-glucose (HY-B0389). D-Glucose- 13C6 can be used as a metabolic tracer to trace glucose-related synthetic catabolism or as synthesis ingredient, minimal media reagent, and internal standard .
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- HY-100196S1
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PQQ-13C3 sodium; Methoxatin-13C3 sodium
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Endogenous Metabolite
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Inflammation/Immunology
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Pyrroloquinoline quinone-13C3 (sodium) is an isotope of Pyrroloquinoline quinone. Pyrroloquinoline quinone (PQQ), a redox co-factor, is an anionic, redox-cycling orthoquinone. Pyrroloquinoline quinone is isolated from cultures of methylotropic bacteria and tissues of mammals. Pyrroloquinoline quinone is an essential nutrient for mammals and is important for immune function .
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- HY-Y0264S
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Isotope-Labeled Compounds
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Infection
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4-Hydroxybenzoic acid- 13C6 is the 13C labeled isotope of 4-Hydroxybenzoic acid- 13C6.4-Hydroxybenzoic acid is a phenolic derivative of benzoic acid, which can inhibit most Gram-positive bacteria and some Gram-negative bacteria with an IC50 value of 160 μg/mL.
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- HY-159001
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Biochemical Assay Reagents
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Others
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ZCDD083 can be used as a positron emission tomography (PET) tracer for atherosclerotic plaques imagination, when labeled with 18F isotope .
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- HY-W654362
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Isotope-Labeled Compounds
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Others
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(R)-2-Thioxothiazolidine-4-carboxylic acid- 13C3 is the 13C-labeled (R)-2-Thioxothiazolidine-4-carboxylic acid. Radioactive isotopes labeled compounds can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified .
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- HY-B1204S2
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- HY-W106014S
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Biphenyl-3-amine-13C6 hydrochloride
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Isotope-Labeled Compounds
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Others
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[1,1'-Biphenyl]-3-amine-13C6 hydrochloride (Biphenyl-3-amine-13C6 hydrochloride) is the 13C labeled isotope of [1,1'-Biphenyl]-3-amine hydrochloride (HY-W106014) .
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![[1,1'-Biphenyl]-3-amine-13C6 hydrochloride](//file.medchemexpress.eu/product_pic/hy-w106014s.gif)
- HY-P5053
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- HY-W777583
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Isotope-Labeled Compounds
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Others
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2-[4-(1-Ethyl-1,4-dimethylpentyl)phenoxy]ethanol-13C6 is the 13C labeled isotope of 2-[4-(1-Ethyl-1,4-dimethylpentyl)phenoxy]ethanol-13C6 (HY-W777583) .
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![2-[4-(1-Ethyl-1,4-dimethylpentyl)phenoxy]ethanol-13C6](//file.medchemexpress.eu/product_pic/hy-w777583.gif)
- HY-W712567
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6-Aminopurine-15N5 hydrochloride; Vitamin B4-15N5 hydrochloride
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Isotope-Labeled Compounds
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Others
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Adenine-15N5 hydrochloride (6-Aminopurine-15N5 hydrochloride) is the 15N labeled isotope of Adenine-15N5 hydrochloride (6-Aminopurine-15N5 hydrochloride; Vitamin B4-15N5 hydrochloride) .
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- HY-136952
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Biochemical Assay Reagents
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Others
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p-SCN-Bn-HOPO is a bifunctional chelating agent. p-SCN-Bn-HOPO is used to bind to the radioactive isotope zirconium-89 (^89Zr) for use in ImmunoPET .
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- HY-W769714
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T-705-13C3
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Isotope-Labeled Compounds
Antibiotic
Bacterial
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Infection
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Favipiravir- 13C3 is the 13C labeled isotope of Favipiravir- 13C3(HY-14768 ).Favipiravir (T-705) is a potent viral RNA polymerase inhibitor, it is phosphoribosylated by cellular enzymes to its active form, Favipiravir-ribofuranosyl-5′-triphosphate (RTP). Favipiravir-RTP inhibits the influenza viral RNA-dependent RNA polymerase (RdRP) activity with an IC50 of 341 nM.
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- HY-P1033S1
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![[Pyr1]-Apelin-13, Pro(13C5,15N) TFA](//file.medchemexpress.eu/product_pic/hy-p1033s1.gif)
- HY-18037
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Phosphodiesterase (PDE)
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Others
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AMG-7980 exhibits high affinity to phosphodiesterase 10A (PDE10A), with a KD of 0.94 nM. AMG-7980 can be used as a tracer of PDE10A, when labeled with radioactive isotope .
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- HY-W749209
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Endogenous Metabolite
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Sodium Acetate-1,2-13C2 is a stable isotope labeled compound with biomarker and metabolic tracking activity. Sodium Acetate-1,2-13C2 is often used in biochemical research for the analysis of metabolic pathways. Sodium Acetate-1,2-13C2 is also used in medical imaging and compound development to improve the understanding of biological processes.
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- HY-W750600
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Methyl cyanide-15N
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Endogenous Metabolite
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Acetonitrile-15N (Methyl cyanide-15N) is a stable isotope labeled organic compound with important applications in metabolic research and molecular labeling. Acetonitrile-15N is used in biolabeling experiments to track metabolic pathways and help understand the chemical reaction mechanisms in organisms. Acetonitrile-15N is also widely used in environmental science to study the migration and transformation processes of pollutants.
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- HY-106950S1
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Diphosphofructose-13C6 tetrasodium hydrate; Esafosfan-13C6 tetrasodium hydrate; FDP-13C6 tetrasodium hydrate
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Endogenous Metabolite
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Cardiovascular Disease
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Fosfructose- 13C6 (tetrasodium hydrate) is the 13C labeled Fosfructose (HY-106950). Fosfructose is a cytoprotective natural sugar phosphate for the potential treatment of cardiovascular ischemia, sickle cell anemia and asthma[1].
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- HY-W009538S1
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Isotope-Labeled Compounds
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Cancer
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5-Fluoro-5'-deoxycytidine-13C5 is the 13C labeled isotope of 5-Fluoro-5'-deoxycytidine (HY-W009538). 5-Fluoro-5'-deoxycytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
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- HY-131673
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Others
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Others
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p-SCN-Bn-TCMC tetrahydrochloride is a bifunctional chelator that exhibits high reactivity due to its powerful TCMC component, making it effective for binding radio-isotopic heavy metal ions, which are essential in radio-diagnostic imaging applications.
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- HY-B0122S
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- HY-W088413A
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Biochemical Assay Reagents
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Cancer
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DOTA-amide (dihydrate) is a Bifunctional Chelators (BFCs). DOTA-amide (dihydrate) binds to the Affibody molecule ZHER2:S1. Its complex binds specifically to HER2 and can be used to detect bone metastases, which are common in prostate cancer .
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- HY-157556
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GHSR
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Others
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BPP-2 is a GHSR ligand with an F element. Using 18F isotope labeling BPP-2, a PET probe targeting GHSR can be obtained. The binding affinity Ki of 18F-BPP-2 for GHSR is 274 nM .
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- HY-B0101S1
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UK-49858-13C2,15N
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Isotope-Labeled Compounds
Fungal
Antibiotic
Bacterial
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Infection
Cancer
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Fluconazole-13C2,15N (UK-49858-13C2,15N) is the 13C and 15N labeled isotope of Fluconazole (HY-B0101). Fluconazole (UK-49858) is a triazole antifungal agent with excellent activities against a broad range of fungi, especially against Candida albicans. Fluconazole inhibits C. albicans and Candida kefyr with IC99s range from 0.20 μg/mL to 0.39 μg/mL .
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- HY-123733A
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RPS-001 TFA
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PSMA
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Cancer
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MIP-1095 (RPS-001) TFA is a potent inhibitor of PSMA with good biodistribution and efficient targeting of tumor lesions. In applications, MIP-1095 TFA will be isotopically labeled ( 131I labeled) as an imaging probe to indicate tumor progression. And 131I-MIP-1095 showed higher renal uptake in mice .
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- HY-10020S
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CP 526555-15N3 Hydrochloride
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nAChR
Isotope-Labeled Compounds
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Neurological Disease
Inflammation/Immunology
Cancer
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Varenicline-15N3 Hydrochloride (CP 526555-15N3 Hydrochloride) is the 15N labeled isotope of Varenicline hydrochloride (HY-10020). Varenicline (CP 526555) is an orally active partial agonist of α4β2 nicotinic acetylcholine receptor (α4β2 nAChR, IC50 = 250 nM), which is the principal mediator of nicotine dependence. Varenicline is also a partial agonist of α6β2 nAChR and a full agonist of α6β2 nAChR. Varenicline blocks the direct agonist effects of nicotine on nAChR while stimulates nAChR in a more moderate way, being widely used as an aid of smoking cessation .
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- HY-14608S12
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L-Glutamic acid-14C
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iGluR
Ferroptosis
Apoptosis
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Neurological Disease
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L-Glutamic acid-14C is L-Glutamic acid (HY-14608) labeled with the radioactive isotope carbon-14. L-Glutamic acid is an excitatory amino acid neurotransmitter and an agonist for all subtypes of glutamate receptors (metabotropic, NMDA, and AMPA). L-Glutamic acid acts as an agonist in the release of DA from dopaminergic nerve terminals and can be used in the study of neurological diseases .
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- HY-P5290
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Radionuclide-Drug Conjugates (RDCs)
PSMA
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Cancer
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HYNIC-PSMA is a ligand for molecular imaging of tumors. Hynic-psma consists of two components: HYNIC (6-hydrazinonicotinamide) and PSMA (Prostate-Specific Membrane Antigen). HYNIC is a compound used to attach radioactive isotopes to targeted molecules, such as 188Re-HYNIC-PSMA. PSMA is a membrane antigen that is specifically expressed on the surface of prostate cancer cells. HYNIC-PSMA can be used in prostate cancer research .
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- HY-136205
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Iodoacetamide-alkyne; N-Hex-5-ynyl-2-iodo-acetamide
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TRP Channel
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Infection
Inflammation/Immunology
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IA-Alkyne (Iodoacetamide-alkyne; N-Hex-5-ynyl-2-iodo-acetamide) is a TRP channel (TRPC) agonist and has the potential for the study of respiratory infection . IA-Alkyne can be used to develop an isotopically tagged probe for quantitative cysteine-reactivity profiling . IA-Alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-118431
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Others
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Others
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DMABA NHS ester can chemically react with the primary amine groups of the major phospholipid component of the cell membrane, Phosphatidylethanolamine (PE). Through precursor ion scanning, all PE subclasses labeled with DMABA can be detected. DMABA NHS ester can be used in combination with isotope-labeled compounds such as DMABA-d6 NHS ester, DMABA-d10 NHS ester, and DMABA-d4 NHS ester to observe changes in the distribution of PE lipids and the formation of novel PE lipid products .
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- HY-P5292
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Radionuclide-Drug Conjugates (RDCs)
PSMA
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Cancer
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HYNIC-iPSMA is a ligand for molecular imaging of tumors. Hynic-ipsma consists of two components: HYNIC (6-hydrazinonicotinamide) and iPSMA (Inhibitor of Prostate-Specific Membrane Antigen). HYNIC is a compound used to attach radioactive isotopes to targeted molecules. iPSMA is a specific inhibitor used to inhibit prostate-specific membrane antigen (PSMA). 68GA-labeled iPSMA has been used to detect prostate cancer by PET imaging. The further 99mTc-EDDA/HYNIC-iPSMA has excellent specificity and sensitivity .
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- HY-158125
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PSMA
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Cancer
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PSMA binder-2 is a ligand for PSMA and can be used to synthesize Ac-PSMA-trillium. Ac-PSMA-trillium is a suitable PSMA-targeting compound with improved PSMA binding properties and pharmacokinetic properties. PSMA ligands have different biological applications after being modified with different radioactive isotopes. If labeled with 111In, it can be used as DOTA chelating agent and imaging agent. Or labeled with 225Ac as a Macropa chelator for targeted radionuclide therapy (TRT) in the study of metastatic castration-resistant prostate cancer (mCRPC) .
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-
- HY-P5292A
-
|
|
Radionuclide-Drug Conjugates (RDCs)
PSMA
|
Cancer
|
|
HYNIC-iPSMA TFA is a ligand for molecular imaging of tumors. Hynic-ipsma consists of two components: HYNIC (6-hydrazinonicotinamide) and iPSMA (Inhibitor of Prostate-Specific Membrane Antigen). HYNIC is a compound used to attach radioactive isotopes to targeted molecules. iPSMA is a specific inhibitor used to inhibit prostate-specific membrane antigen (PSMA). 68GA-labeled iPSMA has been used to detect prostate cancer by PET imaging. The further 99mTc-EDDA/HYNIC-iPSMA TFA has excellent specificity and sensitivity .
|
-
- HY-158119A
-
|
|
PSMA
|
Cancer
|
|
PSMA-trillium is a PSMA targeting compound, consisting of a PSMA targeting molecule (PSMA binder), a Macropa chelating molecule, and a group that regulates pharmacokinetics (PK modifier). PSMA-trillium is a non-radioactive form of Actinium-225-PSMA-Trillium (BAY 3563254) with improved PSMA targeting and pharmacokinetic properties. PSMA-trillium can bind Ac through the Macropa chelating molecule, or the radioactive isotope 225Actinium. Actinium-225-PSMA-Trillium is a potent inhibitor of metastatic castration-resistant prostate cancer (mCRPC) .
|
-
- HY-158123
-
|
|
PSMA
|
Cancer
|
|
PSMA binder-1 is a ligand for PSMA and can be used to synthesize Ac-PSMA-trillium. Ac-PSMA-trillium is a suitable PSMA-targeting compound with improved PSMA binding properties and pharmacokinetic properties. PSMA ligands have different biological applications after being modified with different radioactive isotopes. If labeled with 111In, it can be used as DOTA chelating agent and imaging agent. Or it can be labeled with 225Ac (to obtain Actinium-225-PSMA-Trillium (BAY 3563254)), which has a radioactive killing effect; it can be used as a Macropa chelator for targeted radionuclide therapy (TRT) , has a strong inhibitory effect on metastatic castration-resistant prostate cancer (mCRPC) .
|
-
- HY-P5126
-
|
|
Radionuclide-Drug Conjugates (RDCs)
Somatostatin Receptor
|
Cancer
|
|
DOTA-LM3 is a somatostatin receptor (SSTR) antagonist. LM3 refers to p-Cl-Phe- cyclo(D-Cys-Tyr-D-4-amino-Phe(carbamoyl)-Lys-Thr-Cys)D-Tyr- NH2, as well as a somatostatin antagonist. DOTA-LM3 is often isotopically labeled for tracing tumors in vivo, such as 177Lu-DOTA-LM3 and 68 Ga-DOTA-LM3. 68 Ga-DOTA-LM3 shows favorable biodistribution, high tumor uptake, good tumor retention, and few safety concerns. 177Lu-DOTA-LM3 can be used for research in DOTATOC-negative liver metastases, such as pancreatic NET and extensive tumor thrombosis .
|
-
- HY-P5126A
-
|
|
Radionuclide-Drug Conjugates (RDCs)
Somatostatin Receptor
|
Cancer
|
|
DOTA-LM3 TFA is a somatostatin receptor (SSTR) antagonist. LM3 refers to p-Cl-Phe- cyclo(D-Cys-Tyr-D-4-amino-Phe(carbamoyl)-Lys-Thr-Cys)D-Tyr- NH2, as well as a somatostatin antagonist. DOTA-LM3 TFA is often isotopically labeled for tracing tumors in vivo, such as 177Lu-DOTA-LM3 TFA and 68 Ga-DOTA-LM3 TFA. 68 Ga-DOTA-LM3 TFA shows favorable biodistribution, high tumor uptake, good tumor retention, and few safety concerns. 177Lu-DOTA-LM3 TFA can be used for research in DOTATOC-negative liver metastases, such as pancreatic NET and extensive tumor thrombosis .
|
-
- HY-158122
-
|
|
DNA-PK
|
Cancer
|
|
Lys(CO-C3-p-I-Ph)-O-tBu is a pharmacokinetic modifier (PK modifier) that can improve the PK properties of PSMA ligand molecules. Lys(CO-C3-p-I-Ph)-O-tBu can increase the residence time of PSMA ligand in plasma by increasing its binding capacity to albumin. Lys(CO-C3-p-I-Ph)-O-tBu also reduces salivary gland absorption, possibly extending the half-life of the active compound. Ac-PSMA-trillium is a suitable PSMA-targeting compound that has different biological applications after modification with different radioactive isotopes. If labeled with 111In, it can be used as DOTA chelating agent and imaging agent. Or labeled with 225Ac as a Macropa chelator for targeted radionuclide therapy (TRT) in the study of metastatic castration-resistant prostate cancer (mCRPC) .
|
-
- HY-158118
-
|
|
DNA-PK
|
Cancer
|
|
Lys(CO-C3-p-I-Ph)-OMe is a pharmacokinetic modifier (PK modifier) that can improve the PK properties of PSMA ligand molecules (such as Ac-PSMA-trillium). Lys(CO-C3-p-I-Ph)-OMe can increase the residence time of Ac-PSMA-trillium in plasma by increasing its binding capacity to albumin. Lys(CO-C3-p-I-Ph)-OMe also reduces salivary gland absorption of Ac-PSMA-trillium, potentially extending its half-life. Ac-PSMA-trillium is a suitable PSMA-targeting compound that has different biological applications after modification with different radioactive isotopes. If labeled with 111In, it can be used as DOTA chelating agent and imaging agent. Or labeled with 225Ac as a Macropa chelator for targeted radionuclide therapy (TRT) in the study of metastatic castration-resistant prostate cancer (mCRPC) .
|
-
- HY-14605BS
-
|
AGN1135-13C3; TVP1012-13C3 racemic
|
Isotope-Labeled Compounds
Monoamine Oxidase
|
Neurological Disease
|
|
Rasagiline- 13C3 (mesylate racemic) is a 13C-labeled Rasagiline mesylate racemic. Rasagiline mesylate racemic is a highly potent selective irreversible mitochondrial monoamine oxidase (MAO) inhibitor[1]. Rasagiline-13C3 (mesylate racemic) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-141905S
-
-
- HY-N0216S1
-
|
|
Bacterial
Fungal
Endogenous Metabolite
|
Infection
|
|
Benzoic acid- 13C6 is the 13C-labeled Benzoic acid. Benzoic acid is an aromatic alcohol existing naturally in many plants and is a common additive to food, drinks, cosmetics and other products. It acts as preservatives through inhibiting both bacteria and fungi.
|
-
- HY-B2219S2
-
-
- HY-N0683S
-
-
- HY-W020044S
-
|
|
Ferroptosis
|
Others
|
|
DL-alpha-Tocopherol- 13C3 is the 13C-labeled DL-alpha-Tocopherol. DL-alpha-Tocopherol is a synthetic vitamin E, with antioxidation effect. DL-alpha-Tocopherol protects human skin fibroblasts against the cytotoxic effect of UVB[1].
|
-
- HY-141919S
-
-
- HY-B2130S
-
|
|
Reactive Oxygen Species
Endogenous Metabolite
|
Inflammation/Immunology
|
|
Uric acid- 13C, 15N3 is the 13C-labeled and 15N-labeled Uric acid. Uric acid, scavenger of oxygen radical, is a very important antioxidant that help maintains the stability of blood pressure and antioxidant stress. Uric acid can remove reactive oxygen species (ROS) such as singlet oxygen and peroxynitrite, inhibiting lipid peroxidation[1][2].
|
-
- HY-W141978S
-
-
- HY-N0390S1
-
|
L-Glutamic acid 5-amide-13C5
|
mGluR
Endogenous Metabolite
Ferroptosis
|
Metabolic Disease
|
|
L-Glutamine- 13C5 is the 13C-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells[1][2].
|
-
- HY-W009204S3
-
-
- HY-W017443S
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
L-Asparagine- 13C4, 15N2 (monohydrate)is the 13C-labeled and 15N-labeled L-Asparagine monohydrate. L-Asparagine monohydrate ((-)-Asparagine monohydrate) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue.
|
-
- HY-Y1250S1
-
-
- HY-B0456S1
-
|
Vitamin B2-13C4,15N2-1; E101-13C4,15N2-1
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Others
|
|
Riboflavin-5-Phosphate- 13C4, 15N2-1 is the 13C-labeled and 15N-labeled Riboflavin. Riboflavin is an easily absorbed micronutrient with a key role in maintaining health in humans and other animals.
|
-
- HY-90006S2
-
|
|
Nucleoside Antimetabolite/Analog
HIV
Apoptosis
Endogenous Metabolite
|
Cancer
|
|
5-Fluorouracil- 15N2 is the 15N-labeled 5-Fluorouracil. 5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer[1][2]. 5-Fluorouracil also inhibits HIV[3].
|
-
- HY-N0390S
-
|
L-Glutamic acid 5-amide-15N
|
mGluR
Endogenous Metabolite
Ferroptosis
|
Metabolic Disease
|
|
L-Glutamine- 15N is the 15N-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells[1][2].
|
-
- HY-A0161S
-
|
Clofedanol-13C6; Calmotusin-13C6; NSC 113595-13C6
|
Isotope-Labeled Compounds
|
Infection
|
|
Chlophedianol- 13C6 is the 13C labeled Chlophedianol (HY-A0161). Chlophedianol is an orally active and potent antitussive agent. Chlophedianol can be used for the research of acute cough due to upper respiratory tract infections (URIs)[1][2][3].
|
-
- HY-Y0978S
-
-
- HY-Y0677S
-
-
- HY-32351AS1
-
|
25-Hydroxy Vitamin D3-13C5 monohydrate
|
Isotope-Labeled Compounds
VD/VDR
Endogenous Metabolite
|
Metabolic Disease
|
|
Calcifediol- 13C5 monohydrate is the 13C-labeled Calcifediol monohydrate. Calcifediol monohydrate (25-hydroxy Vitamin D3 monohydrate), is an effective VDR ligand and VD supplement. Calcifediol is a prohormone of the vitamin D endocrine system (VDES) and is hydroxylated in the liver to produce the active form, calcitriol. Calcifediol can rapidly increase serum VD levels .
|
-
- HY-W009204S
-
-
- HY-Y0252S
-
|
|
Endogenous Metabolite
|
Others
|
|
L-Proline- 13C5 is the 13C-labeled L-Proline. L-Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins.
|
-
- HY-N0382S
-
-
- HY-W104010S
-
-
- HY-W001138S
-
-
- HY-W104549S
-
-
- HY-W040047S
-
-
- HY-N0001S
-
-
- HY-34428S
-
-
- HY-B0234S
-
|
E1-13C3; Oestrone-13C3
|
Estrogen Receptor/ERR
Endogenous Metabolite
|
Endocrinology
Cancer
|
|
Estrone- 13C3 is the 13C-labeled Estrone. Estrone (E1) is a natural estrogenic hormone. Estrone is the main representative of the endogenous estrogens and is produced by several tissues, especially adipose tissue. Estrone is the result of the process of aromatization of androstenedione that occurs in fat cells[1][2].
|
-
- HY-B0451AS5
-
-
- HY-130585S
-
-
- HY-N0437S2
-
-
- HY-B0318S
-
|
|
Bacterial
Parasite
Apoptosis
Antibiotic
|
Infection
|
|
Metronidazole- 13C2, 15N2 is the 13C-labeled and 15N-labeled Metronidazole. Metronidazole is a nitroimidazole antibiotic medication used particularly for anaerobic bacteria and protozoa.
|
-
- HY-Y0479S3
-
-
- HY-Z0283S
-
|
Benzenecarboxamide-15N; Phenylamide-15N
|
Endogenous Metabolite
PARP
|
Others
|
|
Benzamide- 15N is a 15N-labeled Benzamide. Benzamide inhibits poly(ADP-ribose) polymerase (PARP)[1][2].
|
-
- HY-18085S2
-
-
- HY-W015824S3
-
-
- HY-13653S
-
|
|
Oxidative Phosphorylation
Autophagy
Reactive Oxygen Species
HIV
Ferroptosis
Mitochondrial Metabolism
Endogenous Metabolite
|
Cancer
|
|
(+/-)-Epigallocatechin Gallate- 13C3 is the 13C-labeled (-)-Epigallocatechin Gallate. (-)-Epigallocatechin Gallate is a tea flavonoid with potent antioxidant, antiinflammatory, and anticarcinogenic properties. (-)-Epigallocatechin Gallate is reported to inhibit EGFR signaling and thereby exert anticancer effects[1]. (-)-Epigallocatechin Gallate (EGCG) is a glutamate dehydrogenase 1/2 (GDH1/2, GLUD1/2) inhibitor. Epigallocatechin-3-gallate induces oxidative phosphorylation (OXPHOS) by activating cytochrome c oxidase.
|
-
- HY-15037S
-
|
|
Isotope-Labeled Compounds
COX
Apoptosis
|
Inflammation/Immunology
|
|
Diclofenac- 13C6 (sodium heminonahydrate) is the 13C-labeled Diclofenac Sodium. Diclofenac Sodium (GP 45840) is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells[1], and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively[2]. Diclofenac Sodium induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade[3].
|
-
- HY-B0843S
-
|
|
Isotope-Labeled Compounds
Fungal
|
Infection
|
|
Metalaxyl- 13C6 is the 13C-labeled Metalaxyl. Metalaxyl is a fungicide that inhibits protein synthesis in fungi. Metalaxyl inhibits the growth of potato blight (P. infestans) fungal isolates from Serbian potato fields (EC50s=0.3-3.9 μg/mL).
|
-
- HY-Y0289S
-
-
- HY-W016498S1
-
-
- HY-N8847S
-
-
- HY-Y0842S
-
-
- HY-Y0946S
-
|
|
Isotope-Labeled Compounds
|
Cancer
|
|
Acetamide- 15N is the 15N-labeled Acetamide. Acetamide is used as an intermediate in the synthesis of methylamine, thioacetamide, and insecticides, and as a plasticizer in leather, cloth and coatings. Acetamide has carcinogenicity[1][2].
|
-
- HY-B0289S
-
-
- HY-N0215S2
-
|
(S)-2-Amino-3-phenylpropionic acid-13C
|
Isotope-Labeled Compounds
Calcium Channel
iGluR
Endogenous Metabolite
|
Metabolic Disease
|
|
L-Phenylalanine- 13C is the 13C-labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4].
|
-
- HY-W014632S
-
|
Desacetyl triflusal-13C6
|
Isotope-Labeled Compounds
|
Others
|
|
4-Trifluoromethylsalicylic acid- 13C6 is the 13C labeled 4-Trifluoromethylsalicylic acid[1]. 4-Trifluoromethylsalicylic acid is a platelet aggregation inhibitor[2].
|
-
- HY-W015913S
-
|
Sodium pyruvate-13C3
|
Reactive Oxygen Species
Endogenous Metabolite
|
Metabolic Disease
|
|
Sodium 2-oxopropanoate- 13C3 is the 13C-labeled Sodium 2-oxopropanoate. Sodium 2-oxopropanoate (Sodium pyruvate), a three-carbon metabolite of Glucose, is a compound produced in the glycolytic pathway. Sodium 2-oxopropanoate is a free radical scavenger that can scavenge ROS[1][2].
|
-
- HY-B0401S1
-
-
- HY-B2033S
-
|
|
Fungal
|
Infection
|
|
Pyrimethanil- 13C, 15N2 is the 13C-labeled and 15N-labeled Pyrimethanil. Pyrimethanil is an anilinopyrimidine and broad-spectrum contact fungicide for the control of Botrytis spp. on a wide variety of crops[1]. Pyrimethanil inhibits the biosynthesis of methionine and other amino acids in Botrytis cinerea. Pyrimethanil can be used for the research of fungal diseases prevention on fruit, vegetable and ornamental plants with mold infection[3].
|
-
- HY-B0178AS
-
|
Guanidinium-13C,15N3 (chloride); Aminoformamidine-13C,15N3 (hydrochloride)
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Guanidine- 13C, 15N3 (hydrochloride)is the 13C-labeled and 15N-labeled Guanidine hydrochloride. Guanidine hydrochloride (Guanidinium chloride) a strong chaotrope, is also a strong denaturant of proteins[1][2].
|
-
- HY-N0486S2
-
-
- HY-N0830S6
-
-
- HY-115584S
-
|
|
Isotope-Labeled Compounds
Parasite
|
Infection
|
|
Lufenuron- 13C6 is a 13C-labeled Lufenuron. Lufenuron is a lipophilic benzoylurea insecticide and a chitin synthesis inhibitor that can used for flea and fish lice control. Lufenuron inhibits moulting of arthropods[1][2].
|
-
- HY-N0216S2
-
|
|
Bacterial
Fungal
Endogenous Metabolite
|
Infection
|
|
Benzoic acid- 13C is the 13C-labeled Benzoic acid. Benzoic acid is an aromatic alcohol existing naturally in many plants and is a common additive to food, drinks, cosmetics and other products. It acts as preservatives through inhibiting both bacteria and fungi.
|
-
- HY-16561S1
-
|
trans-Resveratrol-13C6; SRT501-13C6
|
Isotope-Labeled Compounds
IKK
Autophagy
Mitophagy
Sirtuin
Apoptosis
Bacterial
Fungal
Antibiotic
Keap1-Nrf2
|
Infection
Inflammation/Immunology
Cancer
|
|
Resveratrol- 13C6 is the 13C-labeled Resveratrol. Resveratrol (trans-Resveratrol; SRT501), a natural polyphenolic phytoalexin that possesses anti-oxidant, anti-inflammatory, cardioprotective, and anti-cancer properties. Resveratrol (SRT 501) has a wide spectrum of targets including mTOR, JAK, β-amyloid, Adenylyl cyclase, IKKβ, DNA polymerase. Resveratrol also is a specific SIRT1 activator[1][2][3][4]. Resveratrol is a potent pregnane X receptor (PXR) inhibitor[5]. Resveratrol is an Nrf2 activator, ameliorates aging-related progressive renal injury in mice model[6]. Resveratrol increases production of NO in endothelial cells[7].
|
-
- HY-N0667S4
-
|
(-)-Asparagine-4-13C monohydrate; Asn-4-13C monohydrate; Asparamide-4-13C monohydrate
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Neurological Disease
|
|
L-Asparagine-4- 13C (monohydrate) is the 13C-labeled L-Asparagine. L-Asparagine ((-)-Asparagine) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue.
|
-
- HY-B0451AS6
-
-
- HY-N1981S
-
-
- HY-N0322S4
-
|
|
Estrogen Receptor/ERR
Endogenous Metabolite
|
Metabolic Disease
|
|
Cholesterol- 13C3 is the 13C-labeled Cholesterol. Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins . Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist .
|
-
- HY-N0666S
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
L-Aspartic acid- 13C is a 13C labeled L-Aspartic acid. L-Aspartic acid is is an amino acid, shown to be a suitable proagent for colon-specific agent deliverly[1][2].
|
-
- HY-B0859S
-
|
4-Chloro-2-Methylphenoxyacetic acid-13C8
|
Isotope-Labeled Compounds
|
Others
|
|
MCPA- 13C8 is the 13C-labeled MCPA. MCPA is a phenoxy herbicide, and widely used to control annual and perennial broad leaved weeds, including poppy, thistles and docks, in crops such as cereals, rice, linseed, flax, grassland and turf[1][2].
|
-
- HY-141913S
-
-
- HY-141925S
-
-
- HY-B0434S
-
-
- HY-B1776AS1
-
|
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Metabolic Disease
|
|
Spermidine- 13C4 (hydrochloride) is the 13C-labeled Spermidine trihydrochloride. Spermidine hydrochloride maintains cell membrane stability, increases antioxidant enzymes activities, improving photosystem II (PSII), and relevant gene expression. Spermidine hydrochloride significantly decreases the H2O2 and O2.- contents[1].
|
-
- HY-W013677S
-
-
- HY-15097S
-
-
- HY-14608S
-
|
|
Endogenous Metabolite
iGluR
Ferroptosis
Apoptosis
|
Neurological Disease
|
|
L-Glutamic acid- 13C is the 13C-labeled L-Glutamic acid. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals.
|
-
- HY-141909S
-
-
- HY-17383S
-
-
- HY-B1732S
-
-
- HY-B2156S1
-
|
Vitamin K2(MK-4)-13C6; Menaquinone K4-13C6
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Cancer
|
|
Menaquinone-4- 13C6 is the 13C-labeled Menaquinone-4. Menaquinone-4 is a vitamin K, used as a hemostatic agent, and also a adjunctive therapy for the pain of osteoporosis.
|
-
- HY-W008371S
-
-
- HY-141929S
-
-
- HY-Y1117S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
Melamine- 15N3 is a 15N-labeled Melamine. Melamine is a metabolite of cyromazine. Melamine is a intermediate for the synthesis of melamine resin and plastic materials[1].
|
-
- HY-139145S
-
|
Trimethylopropane phosphate-13C3
|
GABA Receptor
|
Neurological Disease
|
|
Etbicyphat- 13C3 is the 13C labeled Etbicyphat (HY-139145). Etbicyphat is a potent GABA(A) receptors competitive antagonist. Etbicyphat induces epileptiform activities in hippocampal CA1 neurons, and binds to the GABA(A)-benzodiazepine receptors[1][2].
|
-
- HY-W012530S
-
-
- HY-113118S
-
|
|
Endogenous Metabolite
|
Others
|
|
Acetylamino-6-amino-3-methyluracil- 13C4, 15N3 is the 13C and 15N labeled Acetylamino-6-amino-3-methyluracil[1].
|
-
- HY-116084S1
-
-
- HY-19821S
-
-
- HY-113294S
-
|
3-Hydroxy-DL-kynurenine-13C3,15N
|
Isotope-Labeled Compounds
Apoptosis
Endogenous Metabolite
|
Others
|
|
3-Hydroxykynurenine- 13C3, 15N (3-Hydroxy-DL-kynurenine- 13C3, 15N) is the 13C and 15N labeled 3-Hydroxykynurenine (HY-113294) . 3-Hydroxykynurenine, a metabolite of tryptophan, is a potential endogenous neurotoxin whose increased levels have been described in several neurodegenerative disorders. 3-Hydroxykynurenine induces neuronal apoptosis .
|
-
- HY-41877S
-
-
- HY-13632S1
-
|
|
Isotope-Labeled Compounds
Cytochrome P450
|
Endocrinology
Cancer
|
|
Exemestane- 13C3 is the 13C-labeled Exemestane. Exemestane (FCE 24304) is a selective, irreversible and orally active steroidal aromatase inhibitor with IC50s of 30 nM and 40 nM for human placental and rat ovarian aromatase, respectively. Exemestane can be used for hormone-dependent breast cancer research[1][2].
|
-
- HY-N0470S
-
-
- HY-N1428S1
-
-
- HY-B1395S1
-
|
|
Isotope-Labeled Compounds
nAChR
|
Neurological Disease
|
|
Mecamylamine (hydrochloride)- 13C4, 15N is the 13C-labeled and 15N-labeled Mecamylamine hydrochloride. Mecamylamine hydrochloride is an orally active, nonselective, noncompetitive nAChR antagonist that can treat various neuropsychiatric disorders. Mecamylamine hydrochloride is originally used as a ganglionic blocker in treating hypertension. Mecamylamine hydrochloride can easily crosses the blood-brain barrier[1][2].
|
-
- HY-N0521AS
-
|
|
Isotope-Labeled Compounds
|
Cancer
|
|
(+)-Gallocatechin- 13C3 is the 13C-labeled (+)-Gallocatechin. (+)-Gallocatechin is a polyphenol compound from green tea, possesses anticancer activity[1].
|
-
- HY-W010696AS
-
-
- HY-141917S
-
-
- HY-W007318S
-
-
- HY-W015084S
-
|
|
Isotope-Labeled Compounds
Apoptosis
|
Cancer
|
|
β-Ionone- 13C3 is the 13C-labeled β-Ionone. β-Ionone is effective in the induction of apoptosis in gastric adenocarcinoma SGC7901 cells. Anti-cancer activity[1].
|
-
- HY-N0455AS
-
|
(S)-(+)-Arginine-15N2 hydrochloride
|
NO Synthase
Endogenous Metabolite
|
Others
|
|
L-Arginine- 15N2 (hydrochloride) is the 15N-labeled L-Arginine (hydrochloride). L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.
|
-
- HY-W099580S
-
-
- HY-W010407S
-
-
- HY-N1394S
-
-
- HY-W015883S
-
|
|
Endogenous Metabolite
|
Metabolic Disease
Cancer
|
|
Fumaric acid- 13C4 is the 13C-labeled Fumaric acid. Fumaric acid, associated with fumarase deficiency, is identified as an oncometabolite or an endogenous, cancer causing metabolite.
|
-
- HY-N0229S1
-
|
L-2-Aminopropionic acid-1-13C
|
Endogenous Metabolite
|
Neurological Disease
Metabolic Disease
|
|
L-Alanine-1- 13C is the 13C-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.
|
-
- HY-14608S1
-
|
|
Endogenous Metabolite
iGluR
Ferroptosis
Apoptosis
|
Neurological Disease
|
|
L-Glutamic acid-1- 13C is the 13C-labeled L-Glutamic acid. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals.
|
-
- HY-16271S
-
|
|
Isotope-Labeled Compounds
MDM-2/p53
|
Cancer
|
|
Kevetrin (hydrochloride)- 13C2, 15N3 is the 13C-labeled and 15N-labeled Kevetrin (hydrochloride). Kevetrin hydrochloride is a small molecule and activator of the tumor suppressor protein p53, with potential antineoplastic activity.
|
-
- HY-W013495S
-
-
- HY-W006057AS1
-
|
|
Endogenous Metabolite
|
Others
|
|
Sodium 3-methyl-2-oxobutanoate-d hydrate is the deuterium labeled Sodium 3-methyl-2-oxobutanoate. Sodium 3-methyl-2-oxobutanoate is a precursor of pantothenic acid in Escherichia coli[1][2][3].
|
-
- HY-141928S
-
-
- HY-B0337S2
-
-
- HY-B0388S
-
-
- HY-N0356S
-
|
|
Isotope-Labeled Compounds
COX
|
Cancer
|
|
(+/-)-Catechin Gallate- 13C3 is the 13C-labeled (-)-Catechin gallate. (-)-Catechin gallate is a minor constituent in green tea catechins. (-)-Catechin gallate inhibits the activity of COX-1 and COX-2 enzymes.
|
-
- HY-B0504S1
-
-
- HY-W012566S
-
-
- HY-B0412S3
-
-
- HY-18572S
-
|
2,4-Dichlorophenoxyacetic acid-13C6
|
Isotope-Labeled Compounds
DNA/RNA Synthesis
|
Others
|
|
2,4-D- 13C6 is the 13C-labeled 2,4-D. 2,4-D (2,4-Dichlorophenoxyacetic acid) is a selective systemic herbicide for the control of broad-leaved weeds. 2,4-D acts as a plant hormone, causing uncontrolled growth in the meristematic tissues. 2,4-D inhibits DNA and protein synthesis and thereby prevents normal plant growth and development[1].
|
-
- HY-16938S
-
|
5'-(Methylthio)-5'-deoxyadenosine-13C6; 5'-Deoxy-5'-(methylthio)adenosine-13C6; 5'-S-Methyl-5'-thioadenosine-13C6
|
Endogenous Metabolite
Apoptosis
|
Metabolic Disease
Cancer
|
|
5'-Methylthioadenosine- 13C6 is the 13C-labeled 5'-Methylthioadenosine. 5'-Methylthioadenosine (5'-(Methylthio)-5'-deoxyadenosine) is a nucleoside generated from S-adenosylmethionine (SAM) during polyamine synthesis[1]. 5'-Methylthioadenosine suppresses tumors by inhibiting tumor cell proliferation, invasion, and the induction of apoptosis while controlling the inflammatory micro-environments of tumor tissue. 5'-Methylthioadenosine and its associated materials have striking regulatory effects on tumorigenesis[2].
|
-
- HY-B0150S1
-
|
Niacinamide-15N,13C3; Nicotinic acid amide-15N,13C3
|
Endogenous Metabolite
Sirtuin
|
Neurological Disease
Cancer
|
|
Nicotinamide- 15N, 13C3 is the 13C-labeled and 15N-labeled Nicotinamide. Nicotinamide is a form of vitamin B3 that plays essential roles in cell physiology through facilitating NAD+ redox homeostasis and providing NAD+ as a substrate to a class of enzymes that catalyze non-redox reactions. Nicotinamide is an inhibitor of SIRT1.
|
-
- HY-Y0989S2
-
|
1-Phenylethan-1-One-1,2-13C2
|
Isotope-Labeled Compounds
|
Others
|
|
Acetophenone-1,2- 13C2 is the 13C-labeled Acetophenone. Acetophenone is an organic compound with simple structure[1].
|
-
- HY-W014993S
-
|
|
Endogenous Metabolite
|
Others
|
|
1,3-Dimethyluric acid- 13C4, 15N3 is the 13C-labeled and 15N-labeled 1,3-Dimethyluric acid. 1,3-Dimethyluric acid is a product of theophylline metabolism in man. 1,3-Dimethyluric acid is one of the purine components in urinary calculi.
|
-
- HY-N7091S
-
|
|
Isotope-Labeled Compounds
|
Metabolic Disease
|
|
Atrazine- 15N is the 15N-labeled Atrazine. Atrazine is principally used for control of certain annual broadleaf and grass weeds. Atrazine inhibits photophosphorylation but typically does not result in lethality or permanent cell damage in the short term[1].
|
-
- HY-B1337S4
-
|
|
Cholinesterase (ChE)
|
Others
|
|
Choline Chloride- 13C3 is the 13C-labeled Choline (chloride). Choline chloride is an organic compound and a quaternary ammonium salt, an acyl group acceptor and choline acetyltransferase substrate, also is an important additive in feed especially for chickens where it accelerates growth.
|
-
- HY-Y1088S
-
|
3-Phenylpropionic acid-2,3-13C2; 3-Phenylpropanoic acid-2,3-13C2; 3-Phenyl-n-propionic acid-2,3-13C2
|
Endogenous Metabolite
|
Others
|
|
Hydrocinnamic acid-2,3- 13C2 is the 13C-labeled Hydrocinnamic acid. Hydrocinnamic acid is the major rhizospheric compound with known growth regulatory activities.
|
-
- HY-B1456AS
-
|
|
Isotope-Labeled Compounds
Melanocortin Receptor
|
Inflammation/Immunology
|
|
Fenoprofen- 13C6 (sodium hydrate) is the 13C labeled Fenoprofen (HY-B1456A). Fenoprofen is a nonsteroidal anti-inflammatory agent (NSAID). Fenoprofen can be used to to relieve symptoms of arthritis (osteoarthritis and rheumatoid arthritis), such as inflammation, swelling, stiffness, and joint pain. Fenoprofen is an allosteric enhancer for melanocortin receptors. Fenoprofen also increases ERK1/2 activation[1][2][3].
|
-
- HY-N0305S
-
-
- HY-W091039S
-
-
- HY-B0891S1
-
|
17-Hydroxyprogesterone-13C3; 17-OHP-13C3
|
Progesterone Receptor
Endogenous Metabolite
|
Others
|
|
17α-Hydroxyprogesterone- 13C3 is the 13C-labeled 17α-Hydroxyprogesterone. 17α-Hydroxyprogesterone (17-Hydroxyprogesterone) is an endogenous progestogen as well as chemical intermediate in the biosynthesis of other steroid hormones, including the corticosteroids and the androgens and the estrogens.
|
-
- HY-N0351S
-
|
|
Endogenous Metabolite
|
Cancer
|
|
p-Coumaric acid- 13C3 is the 13C-labeled p-Coumaric acid. p-Coumaric acid is the abundant isomer of cinnamic acid which has antitumor and anti-mutagenic activities.
|
-
- HY-141939S
-
-
- HY-N0473S1
-
-
- HY-Y1250S
-
-
- HY-N6618S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
DL-Mannitol- 13C is the 13C-labeled DL-Mannitol. DL-Mannitol is obtained by combining D-mannitol with a sample of Lmannitol obtained by reduction of L-mannono-1, Clactone[1].
|
-
- HY-Y0931S
-
-
- HY-66005S3
-
-
- HY-W008449S1
-
|
|
Endogenous Metabolite
|
Cancer
|
|
1-Methylxanthine- 13C4, 15N3 is the 13C-labeled and 15N-labeled 1-Methylxanthine. 1-Methylxanthine, a caffeine derivative, is an essential human urinary metabolite of caffeine and theophylline (1,3-dimethylxanthine, TP)[1]. 1-Methylxanthine enhances the radiosensitivity of tumor cells[2].
|
-
- HY-W015824S2
-
-
- HY-16637S3
-
-
- HY-Y1027S1
-
-
- HY-N0486S1
-
-
- HY-N1393S
-
|
NSC 3778-13C6; O-Methylsalicylic acid-13C6; Salicylic acid methyl ether-13C6
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Cancer
|
|
2-Methoxybenzoic acid- 13C6 is the 13C-labeled 2-Methoxybenzoic acid. 2-Methoxybenzoic acid (NSC 3778) is used as an internal standard of salicylic acid and its putative biosynthetic precursors in cucumber leaves. Another known use is in the synthesis of Benextramine.
|
-
- HY-B0456S
-
|
Vitamin B2-13C4,15N2; E101-13C4,15N2
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Others
|
|
Riboflavin- 13C4, 15N2is the 13C-labeled and 15N-labeled Riboflavin. Riboflavin is an easily absorbed micronutrient with a key role in maintaining health in humans and other animals.
|
-
- HY-I0626S
-
|
|
Endogenous Metabolite
|
Others
|
|
Cytosine- 13C2, 15N2 is the 13C-labeled and 15N-labeled Cytosine. Cytosine is one of the four main bases found in DNA and RNA. Cytosine modifications exhibit circadian oscillations that are involved in epigenetic diversity and aging[1][2].
|
-
- HY-N0667S2
-
|
(-)-Asparagine-15N2 monohydrate; Asn-15N2 monohydrate; Asparamide-15N2 monohydrate
|
Endogenous Metabolite
|
Neurological Disease
|
|
L-Asparagine- 15N2 (monohydrate) is the 15N-labeled L-Asparagine. L-Asparagine ((-)-Asparagine) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue.
|
-
- HY-W010098S1
-
-
- HY-N0229S
-
-
- HY-B0315S
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Vitamin B12- 13C7 is the 13C-labeled Vitamin B12. Vitamin B12 is a vitamin. Vitamin B12 plays a key role in the normal functioning of the brain and nervous system, and for the formation of blood[1][2].
|
-
- HY-B0430S
-
|
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Others
|
|
Pantothenic acid- 13C3, 15N (hemicalcium) is the 13C-labeled and 15N-labeled D-Pantothenic acid. D-Pantothenic acid is an essential trace nutrient that functions as the obligate precursor of coenzyme A (CoA). D-Pantothenic acid plays key roles in myriad biological processes, including many that regulate carbohydrate, lipid, protein, and nucleic acid metabolism[1].
|
-
- HY-B0574S2
-
|
|
Isotope-Labeled Compounds
COX
|
Inflammation/Immunology
|
|
Mefenamic acid- 13C6 is the 13C-labeled Mefenamic acid. Mefenamic acid is a non-steroidal anti-inflammatory agent, acting as a competitive inhibitor of hCOX-1 and hCOX-2, with IC50s of 40 nM and 3 μM for hCOX-1 and hCOX-2, respectively.
|
-
- HY-N0464S
-
-
- HY-50723S
-
|
|
Endogenous Metabolite
|
Others
|
|
3-Methylxanthine- 13C4, 15N3 is the 13C-labeled and 15N-labeled 3-Methylxanthine. 3-Methylxanthine, a xanthine derivative, is a cyclic guanosine monophosphate (GMP) inhibitor, with an IC50 of 920 μM on guinea-pig isolated trachealis muscle.
|
-
- HY-Y0589S
-
|
3-Carboxybenzonitrile-13C6; 3-Cyanobenzoic acid-13C6; m-Carboxybenzonitrile-13C6
|
Isotope-Labeled Compounds
|
Others
|
|
m-Cyanobenzoic acid- 13C6 is the 13C labeled m-Cyanobenzoic acid[1].
|
-
- HY-Y0781S
-
|
Acetylformic acid-13C sodium
|
Endogenous Metabolite
|
Others
|
|
Pyruvic acid- 13C (sodium) is the 13C-labeled Pyruvic acid. Pyruvic acid is an intermediate metabolite in the metabolism of carbohydrates, proteins, and fats.
|
-
- HY-141932S
-
-
- HY-W013396S
-
-
- HY-N0666S1
-
|
|
Endogenous Metabolite
|
Cardiovascular Disease
|
|
L-Aspartic acid- 13C4, 15N is the 13C-labeled and 15N-labeled L-Aspartic acid. L-Aspartic acid is is an amino acid, shown to be a suitable proagent for colon-specific agent deliverly.
|
-
- HY-141941S
-
-
- HY-I0210S
-
-
- HY-N0683S1
-
-
- HY-W009204S2
-
-
- HY-17461S
-
|
|
Glucocorticoid Receptor
Endogenous Metabolite
|
Inflammation/Immunology
Endocrinology
|
|
Cortisone- 13C3 is the 13C-labeled Cortisone. Cortisone (17-Hydroxy-11-dehydrocorticosterone), an oxidized metabolite of Cortisol (a Glucocorticoid). Cortisone acts as an immunosuppressant and anti-inflammatory agent. Cortisone can partially intervene in binding of Glucocorticoid to Glucocorticoid-receptor at high concentrations[1][3][4].
|
-
- HY-W017072S
-
-
- HY-131501S1
-
-
- HY-N0322S3
-
|
|
Estrogen Receptor/ERR
Endogenous Metabolite
|
Metabolic Disease
|
|
Cholesterol- 13C5 is the 13C-labeled Cholesterol. Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins . Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist .
|
-
- HY-41121S
-
-
- HY-W015824S
-
-
- HY-15398S1
-
-
- HY-Y0219S
-
-
- HY-Y0337S1
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
L-Cysteine- 15N is the 15N-labeled L-Cysteine. L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans[1].
|
-
- HY-W017443S1
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
L-Asparagine-amide- 15N (monohydrate) is the 15N-labeled L-Asparagine (monohydrate). L-Asparagine monohydrate ((-)-Asparagine monohydrate) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue.
|
-
- HY-10002S
-
-
- HY-15407AS
-
|
AHU-377-13C4 hemicalcium salt
|
Isotope-Labeled Compounds
Neprilysin
|
Cardiovascular Disease
|
|
Sacubitril- 13C4 (hemicalcium salt) is a 13C-labeled and deuterium labeled Sacubitril hemicalcium salt. Sacubitril (AHU-377) hemicalcium salt is a potent NEP inhibitor with an IC50 of 5 nM. Sacubitril hemicalcium salt is a component of the heart failure medicine LCZ696[1].
|
-
- HY-76929S
-
-
- HY-N0326S
-
|
|
Endogenous Metabolite
|
Others
|
|
L-Methionine- 15N is the 15N-labeled L-Methionine. L-Methionine is the L-isomer of Methionine, an essential amino acid for human development. Methionine acts as a hepatoprotectant.
|
-
- HY-N0437S1
-
-
- HY-Y0271S
-
|
Carbamide-15N2; Carbonyldiamide-15N2
|
Endogenous Metabolite
|
Cardiovascular Disease
Cancer
|
|
Urea- 15N2 is the 15N-labeled Urea. Urea is a powerful protein denaturant via both direct and indirect mechanisms[1]. A potent emollient and keratolytic agent[2]. Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function[3]. Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry.
|
-
- HY-B2039S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
Bentazone- 13C10, 15N is the 13C-labeled and 15N-labeled Bentazone. Bentazone is a post-emergence herbicide used for selective control of broadleaf weeds and sedges in beans, rice, corn, peanuts, mint and others. It acts by interfering with photosynthesis[1].
|
-
- HY-18341S1
-
-
- HY-16637S2
-
|
(Rac)-Vitamin B9-13C5,15N; (Rac)-Vitamin M-13C5,15N
|
Isotope-Labeled Compounds
DNA/RNA Synthesis
Endogenous Metabolite
|
Cancer
|
|
(Rac)-Folic acid- 13C5, 15N is the 13C-labeled and 15N-labeled Folic acid. Folic acid (Vitamin M; Vitamin B9) is a B vitamin; is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis.
|
-
- HY-Y1027S
-
-
- HY-B1732S1
-
-
- HY-N0667S3
-
|
(-)-Asparagine-13C4 monohydrate; Asn-13C4 monohydrate; Asparamide-13C4 monohydrate
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Neurological Disease
|
|
L-Asparagine- 13C4 (monohydrate) is the 13C-labeled L-Asparagine. L-Asparagine ((-)-Asparagine) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue.
|
-
- HY-W012722BS1
-
|
α-Ketoisocaproic acid-13C sodium
|
Isotope-Labeled Compounds
|
Others
|
|
4-Methyl-2-oxopentanoic acid- 13C (sodium) is the 13C labeled 4-Methyl-2-oxopentanoic acid sodium[1].
|
-
- HY-Y0313S1
-
-
- HY-N0898S
-
-
- HY-B0451AS1
-
-
- HY-W015883AS
-
-
- HY-B0456S2
-
-
- HY-50896S1
-
|
CP-358774-13C6; NSC 718781-13C6; OSI-774-13C6
|
Isotope-Labeled Compounds
EGFR
Autophagy
|
Cancer
|
|
Erlotinib- 13C6 is a 13C-labeled Erlotinib. Erlotinib is a directly acting EGFR tyrosine kinase inhibitor, with an IC50 of 2 nM for human EGFR[1].
|
-
- HY-I0960S
-
|
|
Endogenous Metabolite
|
Cancer
|
|
Uracil- 13C2, 15N2 is the 13C-labeled and 15N-labeled Uracil. Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA.
|
-
- HY-N0771S
-
-
- HY-N0060S1
-
-
- HY-141907S
-
-
- HY-W015824S1
-
-
- HY-12857S
-
-
- HY-10999S1
-
|
|
MEK
Autophagy
Apoptosis
|
Cancer
|
|
Trametinib- 13C6 is the 13C-labeled Trametinib. Trametinib (GSK1120212; JTP-74057) is an orally active MEK inhibitor that inhibits MEK1 and MEK2 with IC50s of about 2 nM. Trametinib activates autophagy and induces apoptosis[1][2].
|
-
- HY-40354S
-
|
Tasocitinib-13C3; CP-690550-13C3
|
JAK
Apoptosis
|
Inflammation/Immunology
Cancer
|
|
Tofacitinib- 13C3 is the 13C-labeled Tofacitinib. Tofacitinib is an orally available JAK3/2/1 inhibitor with IC50s of 1, 20, and 112 nM, respectively.
|
-
- HY-135330
-
|
|
HIV
Reverse Transcriptase
|
Infection
|
|
Lamivudine- 13C, 15N2 is a labelled impurity of Lamivudine (BCH-189). Lamivudine is a nucleoside reverse transcriptase inhibitors (NRTIs), and can inhibit HIV reverse transcriptase 1/2 and the reverse transcriptase of hepatitis B virus .
|
-
- HY-133706S
-
-
- HY-17598S
-
-
- HY-15306S
-
|
SB-497115-13C4
|
Thrombopoietin Receptor
Bacterial
Apoptosis
|
Infection
Cardiovascular Disease
Cancer
|
|
Eltrombopag- 13C4 (SB-497115- 13C4) is 13 sup>C-labeled Z-Eltrombopag. Z-Eltrombopag is an orally active thrombopoietin-receptor non-peptide agonist with platelet-stimulating activity for the study of chronic immune thrombocytopenia. Eltrombopag also has strong inhibitory effects on multidrug-resistant Staphylococcus aureus (Staphylococcus aureus) and can induce apoptosis (apoptosis) in liver cancer cells .
|
-
- HY-Y0479S
-
-
- HY-107372S
-
-
- HY-N0229S2
-
|
L-2-Aminopropionic acid-15N
|
Endogenous Metabolite
|
Neurological Disease
Metabolic Disease
|
|
L-Alanine- 15N is the 15N-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system[1].
|
-
- HY-N0455AS1
-
|
(S)-(+)-Arginine-15N4 hydrochloride
|
Isotope-Labeled Compounds
NO Synthase
Endogenous Metabolite
|
Others
|
|
L-Arginine- 15N4 (hydrochloride) is the 15N-labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis[1].
|
-
- HY-N0666S3
-
-
- HY-Y0966S
-
|
|
Endogenous Metabolite
iGluR
|
Neurological Disease
|
|
Glycine- 15N is the 15N-labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors[1].
|
-
- HY-14608S2
-
|
|
Endogenous Metabolite
iGluR
Ferroptosis
Apoptosis
|
Neurological Disease
|
|
L-Glutamic acid- 15N is the 15N-labeled L-Glutamic acid. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals[1].
|
-
- HY-N0486S3
-
-
- HY-N0771S2
-
-
- HY-N0215S5
-
|
(S)-2-Amino-3-phenylpropionic acid-15N
|
Isotope-Labeled Compounds
Calcium Channel
iGluR
Endogenous Metabolite
|
Metabolic Disease
|
|
L-Phenylalanine- 15N is the 15N-labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4].
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-
- HY-Y0252S2
-
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Endogenous Metabolite
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Others
|
|
L-Proline- 15N is the 15N-labeled L-Proline. L-Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins[1].
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-
- HY-N0658S
-
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Endogenous Metabolite
|
Others
|
|
L-Threonine- 15N is the 15N-labeled L-Threonine. L-Threonine is a natural amino acid, can be produced by microbial fermentation, and is used in food, medicine, or feed[1][2].
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-
- HY-N0717S
-
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Endogenous Metabolite
|
Others
|
|
L-Valine- 15N is the 15N-labeled L-Valine. L-Valine is one of 20 proteinogenic amino acids. L-Valine is an essential amino acid[1][2].
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-
- HY-N0650S
-
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(-)-Serine-13C3; (S)-Serine-13C3
|
Endogenous Metabolite
|
Cancer
|
|
L-Serine- 13C3 is the 13C-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.
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-
- HY-N7091S1
-
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Isotope-Labeled Compounds
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Metabolic Disease
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Atrazine- 13C3, 15N3 is the 13C-labeled and 15N-labeled Atrazine. Atrazine is principally used for control of certain annual broadleaf and grass weeds. Atrazine inhibits photophosphorylation but typically does not result in lethality or permanent cell damage in the short term[1].
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-
- HY-113008AS
-
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(Z)-Urocanic acid-13C3; cis-UCA-13C3
|
Isotope-Labeled Compounds
5-HT Receptor
|
Inflammation/Immunology
|
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cis-Urocanic acid- 13C3 is the 13C-labeled cis-Urocanic acid. cis-Urocanic acid is a 5-HT2A receptor agonist. cis-Urocanic acid binds to 5-HT receptor with relatively high affinity (Kd=4.6 nM). cis-Urocanic acid is an immune modulator that induces immunosuppression by binding to the 5-HT2A receptor[1].
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-
- HY-100760S
-
-
- HY-113357S
-
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Endogenous Metabolite
|
Inflammation/Immunology
|
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m-Coumaric acid- 13C3 is the 13C-labeled m-Coumaric acid. m-Coumaric acid is a polyphenol metabolite from caffeic acid, formed by the gut microflora and the amount in human biofluids is diet-dependant.
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-
- HY-113046S
-
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5-Methyl THF-13C5; 5-MTHF-13C,d5
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Endogenous Metabolite
|
Metabolic Disease
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5-Methyltetrahydrofolic acid- 13C5 is the 13C-labeled 5-Methyltetrahydrofolic acid. 5-Methyltetrahydrofolic acid (5-Methyl THF) is a biologically active form of folic acid. 5-Methyltetrahydrofolic acid is a methylated derivate of tetrahydrofolate. 5-Methyltetrahydrofolic acid is the predominant natural dietary folate and the principal form of folate in plasma and cerebrospinal fluid[1].
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- HY-112499S1
-
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Vitamin K2-7-13C6; Vitamin K2(35)-13C6; Vitamin MK-7-13C6
|
Isotope-Labeled Compounds
|
Cardiovascular Disease
|
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Menaquinone-7- 13C6 is the 13C-labeled Menaquinone-7. Menaquinone-7 (Vitamin K2-7), belongs to a class of K2-vitamin homologs, is originally discovered as the anti-hemorrhagic factors[1]. Menaquinone-7 (Vitamin K2-7) is identified as the most bioactive cofactor for the carboxylation reaction of Gla-proteins [2]. Supplementation with Menaquinone-7 (Vitamin K2-7) is a pharmacological option for activating matrix Gla protein and intervening in the progression of calcific aortic valve stenosis (CAVS)[3].
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- HY-136380S
-
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Isotope-Labeled Compounds
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Others
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Clodinafop-propargyl- 13C6 is the 13C-labeled Clodinafop-propargyl. Clodinafop-propargyl, a main member of aryloxyphenoxy-propionate herbicides, is used for postemergence control of annual grasses in cereals, including Avena, Lolium, Setaria, Phalaris and Alopecurus spp[1]. Clodinafop-propargyl-13C6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-N0680S
-
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Endogenous Metabolite
Apoptosis
HBV
|
Neurological Disease
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Thiamine monochloride- 13C4 (hydrochloride) is the deuterium labeled Thiamine hydrochloride. Thiamine hydrochloride (Thiamine chloride hydrochloride) is an essential micronutrient needed as a cofactor for many central metabolic enzymes.
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- HY-141902S
-
-
- HY-113296S
-
-
- HY-133689AS
-
-
- HY-121267S
-
-
- HY-113062S
-
-
- HY-139921S1
-
-
- HY-Y0721S
-
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m-Bromofluorobenzene-13C6; m-Fluorobromobenzene-13C6; m-Fluorophenyl bromide-13C6
|
Isotope-Labeled Compounds
|
Others
|
|
3-Bromofluorobenzene- 13C6 is the 13C labeled 3-Bromofluorobenzene[1].
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-
- HY-N0830BS
-
-
- HY-N0830BS1
-
-
- HY-N0830S
-
-
- HY-N0830S10
-
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HSP
|
Cardiovascular Disease
Neurological Disease
Metabolic Disease
Cancer
|
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Palmitic acid- 13C2 is the 13C-labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. Palmitic acid can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells[1][2].
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- HY-N0830S3
-
|
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HSP
|
Cardiovascular Disease
Neurological Disease
Metabolic Disease
Cancer
|
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Palmitic acid-1- 13C is the 13C-labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. Palmitic acid can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells[1][2].
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-
- HY-N0830S9
-
|
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HSP
|
Cardiovascular Disease
Neurological Disease
Metabolic Disease
Cancer
|
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Palmitic acid- 13C is the 13C-labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. Palmitic acid can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells[1][2].
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- HY-138622S
-
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Isotope-Labeled Compounds
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Others
|
|
24:0 Lyso PC- 13C6 is the 13C labeled 24:0 Lyso PC. 24:0 Lyso PC is a lysophospholipid (LyP). 24:0 Lyso PC could be used for mRNA drug delivery[1].
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-
- HY-N1446S
-
-
- HY-Y0366S
-
|
|
Endogenous Metabolite
Bacterial
|
Infection
|
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Lauric acid- 13C is the 13C labeled Lauric acid. Lauric acid is a middle chain-free fatty acid with strong bactericidal properties. The EC50s for P. acnes, S.aureus, S. epidermidis, are 2, 6, 4 μg/mL, respectively.
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- HY-W013061S1
-
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Endogenous Metabolite
|
Metabolic Disease
|
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Propane-1,2,3-triyl tripalmitate- 13C3 is the 13C labeled Propane-1,2,3-triyl tripalmitate. Propane-1,2,3-triyl tripalmitate is an endogenous metabolite.
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- HY-N2041S2
-
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Endogenous Metabolite
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Others
|
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Myristic acid- 13C the 13C is labeled Myristic acid. Myristic acid is a saturated 14-carbon fatty acid occurring in most animal and vegetable fats, particularly butterfat and coconut, palm, and nutmeg oils.
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- HY-W012980S1
-
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Endogenous Metabolite
|
Metabolic Disease
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Isovaleric acid- 13C is the 13C labeled Isovaleric acid. Isovaleric acid is a natural fatty acid and known to effect on neonatal death and possible Jamaican vomiting sickness in human.
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- HY-W011873S2
-
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Endogenous Metabolite
|
Neurological Disease
|
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Palmitoleic acid- 13C16 is the 13C labeled Palmitoleic acid. Palmitoleic acid, a composition of fatty acid, is implicated in the prevention of death from cerebrovascular disorders in SHRSP rats.
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- HY-N1446S4
-
-
- HY-41417S4
-
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Caprylic acid-13C4
|
Endogenous Metabolite
|
Metabolic Disease
|
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Octanoic acid- 13C4 is the 13C labeled Octanoic acid. Octanoic acid (Caprylic acid) is an oily liquid with a slightly unpleasant rancid taste and used commercially in the production of esters used in perfumery and also in the manufacture of dyes.
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- HY-41417S3
-
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Caprylic acid-13C
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Octanoic acid- 13C is the 13C labeled Octanoic acid. Octanoic acid (Caprylic acid) is an oily liquid with a slightly unpleasant rancid taste and used commercially in the production of esters used in perfumery and also in the manufacture of dyes.
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-
- HY-W013061S4
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Propane-1,2,3-triyl tripalmitate- 13C3-1 is the 13C labeled Propane-1,2,3-triyl tripalmitate. Propane-1,2,3-triyl tripalmitate is an endogenous metabolite.
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- HY-N2041S4
-
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Endogenous Metabolite
|
Others
|
|
Myristic acid- 13C3 is the 13C labeled Myristic acid. Myristic acid is a saturated 14-carbon fatty acid occurring in most animal and vegetable fats, particularly butterfat and coconut, palm, and nutmeg oils.
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-
- HY-W013812S
-
|
Linoleic Acid-13C18 ethyl ester; Mandenol-13C18
|
Isotope-Labeled Compounds
|
Cardiovascular Disease
|
Ethyl linoleate- 13C18 is the 13C labeled Ethyl linoleate. Ethyl linoleate inhibit the development of atherosclerotic lesions and the expression of inflammatory mediators[1].
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-
- HY-N1446S2
-
-
- HY-B2219S
-
-
- HY-N0729S2
-
|
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Endogenous Metabolite
|
Cardiovascular Disease
Metabolic Disease
|
|
Linoleic acid- 13C18 is the 13C labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism [1][2].
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-
- HY-N0322S5
-
|
|
Estrogen Receptor/ERR
Endogenous Metabolite
|
Metabolic Disease
|
|
Cholesterol- 13C2 is the 13C labeled Cholesterol. Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins . Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist .
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-
- HY-N0728S3
-
|
|
Isotope-Labeled Compounds
PI3K
Akt
|
Cardiovascular Disease
Cancer
|
|
α-Linolenic acid- 13C18 is the 13C labeled α-Linolenic acid. α-Linolenic acid, isolated from seed oils, is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer[1].
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-
- HY-N1482S
-
|
|
Parasite
|
Inflammation/Immunology
|
|
Methyl palmitate- 13C16 is the 13C labeled Methyl palmitate. Methyl palmitate, an acaricidal compound occurring in green walnut husks, inhibits phagocytic activity and immune response. Methyl palmitate also posseses anti-inflammatory and antifibrotic effects[1][2][3].
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-
- HY-N0729S3
-
|
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Endogenous Metabolite
|
Cardiovascular Disease
Metabolic Disease
|
|
Linoleic acid- 13C1 is the 13C labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism [1][2].
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-
- HY-Y0520S
-
|
|
Endogenous Metabolite
|
Inflammation/Immunology
|
|
Itaconic acid- 13C5 is the 13C labeled Itaconic acid. Itaconic acid, a precursor of polymers, chemicals, and fuels, can be synthesized by many fungi. Itaconic acid also is a macrophage-specific metabolite. Itaconic acid mediates crosstalk between macrophage metabolism and peritoneal tumors[1][2].
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-
- HY-N7092S1
-
-
- HY-B0389S10
-
|
Glucose-13C; D-(+)-Glucose-13C; Dextrose-13C
|
Endogenous Metabolite
|
Metabolic Disease
|
|
D-Glucose- 13C is the 13C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].
|
-
- HY-B0389S11
-
|
Glucose-13C-1; D-(+)-Glucose-13C-1; Dextrose-13C-1
|
Endogenous Metabolite
|
Metabolic Disease
|
|
D-Glucose- 13C-1 is the 13C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].
|
-
- HY-B0389S12
-
|
Glucose-13C-2; D-(+)-Glucose-13C-2; Dextrose-13C-2
|
Endogenous Metabolite
|
Metabolic Disease
|
|
D-Glucose- 13C-2 is the 13C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].
|
-
- HY-N7092S2
-
|
D(-)-Fructose-13C-1
|
Endogenous Metabolite
|
Others
|
|
D-Fructose- 13C-1 is the 13C labeled D-Fructose. D-Fructose (D(-)-Fructose) is a naturally occurring monosaccharide found in many plants.
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-
- HY-N7092S
-
|
D(-)-Fructose-13C6
|
Endogenous Metabolite
|
Others
|
|
D-Fructose- 13C6 is the 13C labeled D-Fructose. D-Fructose (D(-)-Fructose) is a naturally occurring monosaccharide found in many plants.
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-
- HY-B0389S14
-
|
Glucose-13C2; D-(+)-Glucose-13C2; Dextrose-13C2
|
Endogenous Metabolite
|
Metabolic Disease
|
|
D-Glucose- 13C2 is the 13C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].
|
-
- HY-B0389S16
-
|
Glucose-13C-4; D-(+)-Glucose-13C-4; Dextrose-13C-4
|
Endogenous Metabolite
|
Metabolic Disease
|
|
D-Glucose- 13C-4 is the 13C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].
|
-
- HY-B0389S18
-
|
Glucose-13C3-1; D-(+)-Glucose-13C3-1; Dextrose-13C3-1
|
Endogenous Metabolite
|
Metabolic Disease
|
|
D-Glucose- 13C3-1 is the 13C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].
|
-
- HY-B0389S17
-
|
Glucose-13C-5; D-(+)-Glucose-13C-5; Dextrose-13C-5
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Metabolic Disease
|
|
D-Glucose- 13C-5 is the 13C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].
|
-
- HY-B0389S15
-
|
Glucose-13C2-4; D-(+)-Glucose-13C2-4; Dextrose-13C2-4
|
Endogenous Metabolite
|
Metabolic Disease
|
|
D-Glucose- 13C2-4 is the 13C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].
|
-
- HY-N7092S3
-
|
|
Endogenous Metabolite
|
Others
|
|
D-Fructose- 13C2 is the 13C labeled D-Fructose. D-Fructose (D(-)-Fructose) is a naturally occurring monosaccharide found in many plants.
|
-
- HY-B0389S13
-
|
Glucose-13C-3; D-(+)-Glucose-13C-3; Dextrose-13C-3
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Metabolic Disease
|
|
D-Glucose- 13C-3 is the 13C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].
|
-
- HY-B0389S9
-
|
Glucose-13C3-2; D-(+)-Glucose-13C3-2; Dextrose-13C3-2
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Metabolic Disease
|
|
D-Glucose- 13C3-2 is the 13C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].
|
-
- HY-101037S
-
|
N-Methylglycine-15N; Sarcosin-15N
|
Endogenous Metabolite
GlyT
|
Cancer
|
|
Sarcosine- 15N is the 15N-labeled Sarcosine. Sarcosine (N-Methylglycine), an endogenous amino acid, is a competitive glycine transporter type I (GlyT1) inhibitor and N-methyl-D-aspartate (NMDA) receptor co-agonist. Sarcosine increases the glycine concentration, resulting in an indirect potentiation of the NMDA receptor. Sarcosine is commonly used for the research of schizophrenia[1][2].
|
-
- HY-140346AS
-
|
|
Isotope-Labeled Compounds
PROTAC Linkers
|
Cancer
|
|
L-Azidohomoalanine-1,2,3,4- 13C4 (hydrochloride) is the 13C- and 15N-labeled L-Azidohomoalanine hydrochloride. L-Azidohomoalanine hydrochloride is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. L-Azidohomoalanine-1,2,3,4-13C4 (hydrochloride) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-14608S3
-
-
- HY-14608S5
-
|
|
Endogenous Metabolite
iGluR
Ferroptosis
Apoptosis
|
Neurological Disease
|
|
L-Glutamic acid- 13C5 is the 13C-labeled L-Glutamic acid. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals.
|
-
- HY-14608S6
-
-
- HY-N0067S3
-
|
4-Aminobutyric acid-13C4
|
Isotope-Labeled Compounds
GABA Receptor
Endogenous Metabolite
|
Neurological Disease
|
|
γ-Aminobutyric acid- 13C4 is the 13C-labeled γ-Aminobutyric acid. γ-Aminobutyric acid (4-Aminobutyric acid) is a major inhibitory neurotransmitter in the adult mammalian brain[1][2], binding to the ionotropic GABA receptors (GABAA receptors) and metabotropic receptors (GABAB receptors)[2].
|
-
- HY-N0215S10
-
|
(S)-2-Amino-3-phenylpropionic acid-13C9
|
Isotope-Labeled Compounds
Calcium Channel
iGluR
Endogenous Metabolite
|
Metabolic Disease
|
|
L-Phenylalanine- 13C9 is the 13C-labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4].
|
-
- HY-N0215S11
-
|
(S)-2-Amino-3-phenylpropionic acid-13C9,15N
|
Calcium Channel
iGluR
Endogenous Metabolite
|
Metabolic Disease
|
|
L-Phenylalanine- 13C9, 15N is the 13C- and 15N-labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4].
|
-
- HY-N0215S7
-
|
(S)-2-Amino-3-phenylpropionic acid-3-13C
|
Calcium Channel
iGluR
Endogenous Metabolite
|
Metabolic Disease
|
|
L-Phenylalanine-3- 13C is the 13C-labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4].
|
-
- HY-N0215S8
-
|
(S)-2-Amino-3-phenylpropionic acid-13C6
|
Isotope-Labeled Compounds
Calcium Channel
iGluR
Endogenous Metabolite
|
Metabolic Disease
|
|
L-Phenylalanine- 13C6 is the 13C-labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4].
|
-
- HY-N0229S10
-
-
- HY-N0229S11
-
-
- HY-N0229S6
-
-
- HY-N0229S7
-
-
- HY-N0229S8
-
|
L-2-Aminopropionic acid-13C3
|
Endogenous Metabolite
|
Neurological Disease
Metabolic Disease
|
|
L-Alanine- 13C3 is the 13C-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.
|
-
- HY-N0229S9
-
|
L-2-Aminopropionic acid-13C2
|
Endogenous Metabolite
|
Neurological Disease
Metabolic Disease
|
|
L-Alanine- 13C2 is the 13C-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.
|
-
- HY-N0230S
-
|
2-Carboxyethylamine-13C3,15N; 3-Aminopropanoic acid-13C3,15N
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Metabolic Disease
|
|
β-Alanine- 13C3, 15N is the 13C- and 15N-labeled β-Alanine. β-Alanine is a non-essential amino acid that is shown to be metabolized into carnosine, which functions as an intracellular buffer.
|
-
- HY-N0230S1
-
|
2-Carboxyethylamine-15N; 3-Aminopropanoic acid-15N
|
Endogenous Metabolite
|
Metabolic Disease
|
|
β-Alanine- 15N is the 15N-labeled β-Alanine. β-Alanine is a non-essential amino acid that is shown to be metabolized into carnosine, which functions as an intracellular buffer.
|
-
- HY-N0326S3
-
|
|
Endogenous Metabolite
|
Others
|
|
L-Methionine- 13C is the 13C-labeled L-Methionine. L-Methionine is the L-isomer of Methionine, an essential amino acid for human development. Methionine acts as a hepatoprotectant.
|
-
- HY-N0326S4
-
|
|
Endogenous Metabolite
|
Others
|
|
L-Methionine-1- 13C is the 13C-labeled L-Methionine. L-Methionine is the L-isomer of Methionine, an essential amino acid for human development. Methionine acts as a hepatoprotectant.
|
-
- HY-N0326S5
-
|
|
Endogenous Metabolite
|
Others
|
|
L-Methionine- 13C5 is the 13C-labeled L-Methionine. L-Methionine is the L-isomer of Methionine, an essential amino acid for human development. Methionine acts as a hepatoprotectant.
|
-
- HY-N0326S6
-
|
|
Endogenous Metabolite
|
Others
|
|
L-Methionine- 13C5, 15N is the 13C- and 15N-labeled L-Methionine. L-Methionine is the L-isomer of Methionine, an essential amino acid for human development. Methionine acts as a hepatoprotectant.
|
-
- HY-N0390S4
-
|
L-Glutamic acid 5-amide-5-13C
|
mGluR
Endogenous Metabolite
Ferroptosis
|
Metabolic Disease
|
|
L-Glutamine-5- 13C is the 13C-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells[1][2].
|
-
- HY-N0390S5
-
|
L-Glutamic acid 5-amide-1-13C
|
mGluR
Endogenous Metabolite
Ferroptosis
|
Metabolic Disease
|
|
L-Glutamine-1- 13C is the 13C-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells[1][2].
|
-
- HY-N0390S6
-
|
L-Glutamic acid 5-amide-13C5,15N2
|
mGluR
Endogenous Metabolite
Ferroptosis
|
Metabolic Disease
|
|
L-Glutamine- 13C5, 15N2 is the 13C- and 15N-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells[1][2].
|
-
- HY-N0390S8
-
|
L-Glutamic acid 5-amide-15N2
|
mGluR
Endogenous Metabolite
Ferroptosis
|
Metabolic Disease
|
|
L-Glutamine- 15N2 is the 15N-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells[1][2].
|
-
- HY-N0390S9
-
|
L-Glutamic acid 5-amide-15N-1
|
mGluR
Endogenous Metabolite
Ferroptosis
|
Metabolic Disease
|
|
L-Glutamine- 15N-1 is the 15N-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells[1][2].
|
-
- HY-N0391S3
-
|
|
Endogenous Metabolite
|
Others
|
|
L-Citrulline- 13C is the 13C-labeled L-Citrulline. L-Citrulline is an amino acid derived from ornithine in the catabolism of proline or glutamine and glutamate, or from l-arginine via arginine-citrulline pathway.
|
-
- HY-N0394S2
-
|
|
Endogenous Metabolite
Ferroptosis
|
Others
|
|
(S)-L-Cystine- 15N2 is the 15N-labeled L-Cystine. L-Cystine is an amino acid and intracellular thiol, which plays a critical role in the regulation of cellular processes.
|
-
- HY-N0455AS3
-
|
(S)-(+)-Arginine-1-13C hydrochloride
|
NO Synthase
Endogenous Metabolite
|
Others
|
|
L-Arginine-1- 13C (hydrochloride) is the 13C-labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.
|
-
- HY-N0455AS5
-
|
(S)-(+)-Arginine-1,2-13C2 hydrochloride
|
Isotope-Labeled Compounds
NO Synthase
Endogenous Metabolite
|
Others
|
|
L-Arginine-1,2- 13C2 (hydrochloride) is the 13C-labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.
|
-
- HY-N0455AS6
-
|
(S)-(+)-Arginine-13C6 hydrochloride
|
Isotope-Labeled Compounds
NO Synthase
Endogenous Metabolite
|
Others
|
|
L-Arginine- 13C6 (hydrochloride) is the 13C-labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.
|
-
- HY-N0455AS7
-
|
(S)-(+)-Arginine-13C hydrochloride
|
NO Synthase
Endogenous Metabolite
|
Others
|
|
L-Arginine- 13C (hydrochloride) is the 13C-labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.
|
-
- HY-N0455AS8
-
|
(S)-(+)-Arginine-13C6,15N4 hydrochloride
|
NO Synthase
Endogenous Metabolite
|
Others
|
|
L-Arginine- 13C6, 15N4 (hydrochloride) is the 13C- and 15N-labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.
|
-
- HY-N0469S1
-
|
|
Endogenous Metabolite
Virus Protease
|
Inflammation/Immunology
|
|
L-Lysine- 13C6 (dihydrochloride) is the 13C-labeled L-Lysine dihydrochloride. L-lysine dihydrochloride is an essential amino acid[1][2] with important roles in connective tissues and carnitine synthesis, energy production, growth in children, and maintenance of immune functions[2].
|
-
- HY-N0469S2
-
|
|
Endogenous Metabolite
Virus Protease
|
Inflammation/Immunology
|
|
L-Lysine- 15N-1 (dihydrochloride) is the 15N-labeled L-Lysine. L-lysine is an essential amino acid[1][2] with important roles in connective tissues and carnitine synthesis, energy production, growth in children, and maintenance of immune functions[2].
|
-
- HY-N0470S2
-
-
- HY-N0473S12
-
-
- HY-N0473S2
-
-
- HY-N0473S3
-
-
- HY-N0473S4
-
-
- HY-N0473S5
-
-
- HY-N0473S6
-
-
- HY-N0473S7
-
-
- HY-N0486S10
-
-
- HY-N0486S5
-
-
- HY-N0486S6
-
|
|
mTOR
Endogenous Metabolite
|
Metabolic Disease
|
|
L-Leucine-2- 13C, 15N is the 13C- and 15N-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway[1].
|
-
- HY-N0486S7
-
|
|
mTOR
Endogenous Metabolite
|
Metabolic Disease
|
|
L-Leucine-1- 13C, 15N is the 13C- and 15N-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway[1].
|
-
- HY-N0486S8
-
|
|
mTOR
Endogenous Metabolite
|
Metabolic Disease
|
|
L-Leucine- 13C6, 15N is the 13C- and 15N-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway[1].
|
-
- HY-N0623S1
-
|
Tryptophan-13C; Tryptophane-13C
|
Endogenous Metabolite
|
Metabolic Disease
|
|
L-Tryptophan- 13C is the 13C-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1].
|
-
- HY-N0623S2
-
-
- HY-N0623S3
-
-
- HY-N0623S4
-
|
Tryptophan-13C11,15N2; Tryptophane-13C11,15N2
|
Endogenous Metabolite
|
Metabolic Disease
|
|
L-Tryptophan- 13C11, 15N2 is the 13C- and 15N-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1].
|
-
- HY-N0623S7
-
-
- HY-N0623S8
-
|
Tryptophan-15N2; Tryptophane-15N2
|
Endogenous Metabolite
|
Metabolic Disease
|
|
L-Tryptophan- 15N2 is the 15N-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1].
|
-
- HY-N0650S1
-
|
(-)-Serine-13C; (S)-Serine-13C
|
Endogenous Metabolite
|
Cancer
|
|
L-Serine- 13C is the 13C-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.
|
-
- HY-N0650S10
-
|
(-)-Serine-15N; (S)-Serine-15N
|
Endogenous Metabolite
|
Cancer
|
|
L-Serine- 15N is the 15N-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.
|
-
- HY-N0650S2
-
|
(-)-Serine-1-13C; (S)-Serine-1-13C
|
Endogenous Metabolite
|
Cancer
|
|
L-Serine-1- 13C is the 13C-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.
|
-
- HY-N0650S4
-
|
(-)-Serine-2-13C; (S)-Serine-2-13C
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Cancer
|
|
L-Serine-2- 13C is the 13C-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.
|
-
- HY-N0650S5
-
|
(-)-Serine-13C3,15N; (S)-Serine-13C3,15N
|
Endogenous Metabolite
|
Cancer
|
|
L-Serine- 13C3, 15N is the 13C- and 15N-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.
|
-
- HY-N0650S6
-
|
(-)-Serine-13C,15N; (S)-Serine-13C,15N
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Cancer
|
|
L-Serine1- 13C, 15N is the 13C- and 15N-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.
|
-
- HY-N0658S3
-
|
|
Endogenous Metabolite
|
Others
|
|
L-Threonine- 13C4, 15N is the 13C- and 15N-labeled L-Threonine. L-Threonine is a natural amino acid, can be produced by microbial fermentation, and is used in food, medicine, or feed[1].
|
-
- HY-N0666S4
-
-
- HY-N0666S6
-
-
- HY-N0666S7
-
-
- HY-N0717S1
-
|
Valine-13C5,15N
|
Endogenous Metabolite
|
Others
|
|
L-Valine- 13C5, 15N is the 13C- and 15N-labeled L-Valine. L-Valine is one of 20 proteinogenic amino acids. L-Valine is an essential amino acid[1].
|
-
- HY-N0717S4
-
|
|
Endogenous Metabolite
|
Others
|
|
L-Valine-1- 13C is the 13C-labeled L-Valine. L-Valine is one of 20 proteinogenic amino acids. L-Valine is an essential amino acid[1].
|
-
- HY-N0717S5
-
-
- HY-N0717S6
-
|
Valine-13C5
|
Endogenous Metabolite
|
Others
|
|
L-Valine- 13C5 is the 13C-labeled L-Valine. L-Valine is one of 20 proteinogenic amino acids. L-Valine is an essential amino acid[1].
|
-
- HY-N0717S7
-
-
- HY-N0771S4
-
|
|
Endogenous Metabolite
|
Others
|
|
L-Isoleucine-1- 13C is the 13C-labeled L-Isoleucine. L-isoleucine is a nonpolar hydrophobic amino acid[1]. L-Isoleucine is an essential amino acid.
|
-
- HY-N2362S
-
|
DL-2-Aminopropionic acid-13C-1
|
Endogenous Metabolite
|
Metabolic Disease
|
|
DL-Alanine- 13C-1 is the 13C-labeled DL-Alanine. DL-alanine, an amino acid, is the racemic compound of L- and D-alanine. DL-alanine is employed both as a reducing and a capping agent, used with silver nitrate aqueous solutions for the production of nanoparticles. DL-alanine can be used for the research of transition metals chelation, such as Cu(II), Zn(II), Cd(11). DL-alanine, a sweetener, is classed together with glycine, and sodium saccharin. DL-alanine plays a key role in the glucose-alanine cycle between tissues and liver[1][2][3][4][5][6].
|
-
- HY-N2362S1
-
|
DL-2-Aminopropionic acid-13C-3
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Metabolic Disease
|
|
DL-Alanine- 13C-3 is the 13C-labeled DL-Alanine. DL-alanine, an amino acid, is the racemic compound of L- and D-alanine. DL-alanine is employed both as a reducing and a capping agent, used with silver nitrate aqueous solutions for the production of nanoparticles. DL-alanine can be used for the research of transition metals chelation, such as Cu(II), Zn(II), Cd(11). DL-alanine, a sweetener, is classed together with glycine, and sodium saccharin. DL-alanine plays a key role in the glucose-alanine cycle between tissues and liver[1][2][3][4][5][6].
|
-
- HY-W008452S
-
|
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Metabolic Disease
|
|
H-Tyr(3-I)-OH- 13C6 is the 13C-labeled H-Tyr(3-I)-OH. H-Tyr(3-I)-OH is a potent and effective tyrosine hydroxylase inhibitor. H-Tyr(3-I)-OH is an intermediate in the production of thyroid hormones and has a role as a human or mouse metabolite[1][2].
|
-
- HY-W012340S
-
-
- HY-W014423S
-
|
H-His-OH-13C hydrochloride hydrate
|
Endogenous Metabolite
|
Metabolic Disease
|
|
L-Histidine- 13C (hydrochloride hydrate) is the 13C-labeled L-Histidine hydrochloride hydrate. L-Histidine hydrochloride hydrate (H-His-OH.HCl.H2O) is an endogenous metabolite.
|
-
- HY-W014423S2
-
|
H-His-OH-13C6 hydrochloride hydrate
|
Endogenous Metabolite
|
Metabolic Disease
|
|
L-Histidine- 13C6 (hydrochloride hydrate) is the 13C-labeled L-Histidine hydrochloride hydrate. L-Histidine hydrochloride hydrate (H-His-OH.HCl.H2O) is an endogenous metabolite.
|
-
- HY-W014423S3
-
-
- HY-W014423S5
-
-
- HY-W014423S6
-
-
- HY-W016562S3
-
|
2-Benzamidoacetic acid-15N
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Hippuric acid- 15N is the 15N-labeled Hippuric acid. Hippuric Acid (2-Benzamidoacetic acid), an acyl glycine produced by the conjugation of benzoic acid and glycine, is a normal component in urine as a metabolite of aromatic compounds from food.
|
-
- HY-W017018S1
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
L-Ornithine-1,2- 13C2 (hydrochloride) is the 13C-labeled L-Ornithine hydrochloride. L-Ornithine hydrochloride is a free amino acid that plays a central role in the urea cycle and is also important for the disposal of excess nitrogen.
|
-
- HY-W017018S2
-
-
- HY-W017018S5
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
L-Ornithine- 15N2 (hydrochloride) is the 15N-labeled L-Ornithine hydrochloride. L-Ornithine hydrochloride is a free amino acid that plays a central role in the urea cycle and is also important for the disposal of excess nitrogen.
|
-
- HY-Y0123S
-
|
|
Isotope-Labeled Compounds
|
Neurological Disease
|
|
DL-Tyrosine- 13C9, 15N is the 13C- and 15N-labeled DL-Tyrosine. DL-Tyrosine is an aromatic nonessential amino acid synthesized from the essential amino acid phenylalanine. DL-Tyrosine is a precursor for several important neurotransmitters (epinephrine, norepinephrine, dopamine)[1].
|
-
- HY-Y0252S3
-
|
|
Endogenous Metabolite
|
Others
|
|
L-Proline- 13C is the 13C-labeled L-Proline. L-Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins.
|
-
- HY-Y0252S4
-
|
|
Endogenous Metabolite
|
Others
|
|
L-Proline- 13C5,1- 15N is the 13C- and 15N-labeled L-Proline. L-Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins.
|
-
- HY-Y0337S
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
L-Cysteine- 13C3, 15N is the 13C- and 15N-labeled L-Cysteine. L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans[1].
|
-
- HY-Y0337S2
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
L-Cysteine-3- 13C is the 13C-labeled L-Cysteine. L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans[1].
|
-
- HY-Y0337S3
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
L-Cysteine-1- 13C is the 13C-labeled L-Cysteine. L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans[1].
|
-
- HY-Y0337S4
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
L-Cysteine- 13C3 is the 13C-labeled L-Cysteine. L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans[1].
|
-
- HY-Y0966S2
-
|
|
Endogenous Metabolite
iGluR
|
Neurological Disease
|
|
Glycine-2- 13C is the 13C-labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors.
|
-
- HY-Y0966S3
-
-
- HY-Y0966S4
-
|
|
Endogenous Metabolite
iGluR
|
Neurological Disease
|
|
Glycine-1- 13C is the 13C-labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors.
|
-
- HY-Y0966S5
-
-
- HY-Y0966S6
-
|
|
Endogenous Metabolite
iGluR
|
Neurological Disease
|
|
Glycine- 13C2, 15N is the 13C- and 15N-labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors.
|
-
- HY-Y0966S7
-
-
- HY-118877
-
|
|
Isotope-Labeled Compounds
|
Infection
|
|
Urea- 13C is the 13C labelled urea. The Urea- 13C breath test ( 13C-UBT) is one of the best methods for the diagnosis of Helicobacter pylori infection[1].
|
-
- HY-113251S1
-
-
- HY-113252S1
-
-
- HY-12033S1
-
|
2-ME2-13C6; NSC-659853-13C6
|
Isotope-Labeled Compounds
Microtubule/Tubulin
Reactive Oxygen Species
Apoptosis
Autophagy
Endogenous Metabolite
|
Cancer
|
|
2-Methoxyestradiol- 13C6 is the 13C-labeled 2-Methoxyestradiol. 2-Methoxyestradiol (2-ME2), an orally active endogenous metabolite of 17β-estradiol (E2), is an apoptosis inducer and an angiogenesis inhibitor with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules. 2-Methoxyestradio, also a potent superoxide dismutase (SOD) inhibitor and a ROS-generating agent, induces autophagy in the transformed cell line HEK293 and the cancer cell lines U87 and HeLa[1][2][3][4][5][6].
|
-
- HY-124489S
-
|
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Metabolic Disease
|
|
2-Hydroxyestradiol- 13C6 is the 13C-labeled 2-Hydroxyestradiol. 2-Hydroxyestradiol, a metabolite of 17β-estradiol with minimal estrogenic activity, possesses antioxidant effects and reacts with DNA to form stable adducts and exerts genotoxicity[1][3].
|
-
- HY-76847S2
-
-
- HY-B0141S4
-
-
- HY-B0141S5
-
-
- HY-B0143S3
-
-
- HY-B0150S2
-
|
Niacinamide-13C6; Nicotinic acid amide-13C6
|
Endogenous Metabolite
Sirtuin
|
Neurological Disease
Cancer
|
|
Nicotinamide- 13C6 is the 13C-labeled Nicotinamide. Nicotinamide is a form of vitamin B3 that plays essential roles in cell physiology through facilitating NAD+ redox homeostasis and providing NAD+ as a substrate to a class of enzymes that catalyze non-redox reactions. Nicotinamide is an inhibitor of SIRT1.
|
-
- HY-B0166S
-
-
- HY-B0166S1
-
-
- HY-B0216S2
-
-
- HY-B0234S3
-
|
E1-13C2; Oestrone-13C2
|
Isotope-Labeled Compounds
Estrogen Receptor/ERR
Endogenous Metabolite
|
Endocrinology
Cancer
|
|
Estrone- 13C2 is the 13C-labeled Estrone. Estrone (E1) is a natural estrogenic hormone. Estrone is the main representative of the endogenous estrogens and is produced by several tissues, especially adipose tissue. Estrone is the result of the process of aromatization of androstenedione that occurs in fat cells[1][2].
|
-
- HY-B0351S1
-
|
2-Aminoethanesulfonic acid-13C2
|
Autophagy
Endogenous Metabolite
|
Metabolic Disease
|
|
Taurine- 13C2 is the 13C-labeled Taurine. Taurine, a sulphur-containing amino acid and an organic osmolyte involved in cell volume regulation, provides a substrate for the formation of bile salts, and plays a role in the modulation of intracellular free calcium concentration. Taurine has the ability to activate autophagy in adipocytes[1][2][3].
|
-
- HY-B0351S2
-
|
2-Aminoethanesulfonic acid-13C2,15N
|
Isotope-Labeled Compounds
Autophagy
Endogenous Metabolite
|
Metabolic Disease
|
|
Taurine- 13C2, 15N is the 13C- and 15N- labeled Taurine. Taurine, a sulphur-containing amino acid and an organic osmolyte involved in cell volume regulation, provides a substrate for the formation of bile salts, and plays a role in the modulation of intracellular free calcium concentration. Taurine has the ability to activate autophagy in adipocytes[1][2][3].
|
-
- HY-N0324S2
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Cholic acid- 13C is the 13C-labeled Cholic acid. Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion.
|
-
- HY-N0384S3
-
|
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Metabolic Disease
|
|
Homovanillic acid- 13C6, 18O is the 13C-labeled Homovanillic acid. Homovanillic acid is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency.
|
-
- HY-N0437S3
-
-
- HY-N0545S
-
-
- HY-N0593S3
-
-
- HY-N0680S3
-
-
- HY-N0682S3
-
|
Pyridoxol-13C4 hydrochloride; Vitamin B6-13C4 hydrochloride
|
Isotope-Labeled Compounds
Endogenous Metabolite
Keap1-Nrf2
|
Neurological Disease
|
|
Pyridoxine- 13C4 (hydrochloride) is the 13C-labeled Pyridoxine (hydrochloride). Pyridoxine hydrochloride (Pyridoxol; Vitamin B6) is a pyridine derivative. Pyridoxine (Pyridoxol; Vitamin B6) exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway.
|
-
- HY-W008253S3
-
-
- HY-B0322S1
-
|
|
Antibiotic
Bacterial
|
Infection
|
|
Sulfamethoxazole- 13C6 is a 13C labeled Sulfamethoxazole. Sulfamethoxazole (Ro 4-2130) is a sulfonamide bacteriostatic antibiotic, used for bacterial infections. Sulfonamides is a competitive antagonist of para-aminobenzoic acid (PABA)[1].
|
-
- HY-B0273S1
-
-
- HY-A0181S
-
|
AMP-13C10,15N5
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Adenosine monophosphate- 13C10, 15N5 is the 13C-labeled and 15N-labeled Adenosine monophosphate. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction[1].
|
-
- HY-79096S
-
-
- HY-W000450S
-
-
- HY-N0832S
-
-
- HY-N0470S3
-
-
- HY-19528S1
-
|
SAH (S-Adenosylhomocysteine)-13C5
|
Endogenous Metabolite
|
Metabolic Disease
|
|
SAH- 13C5 is the 13C-labeled SAH. SAH (S-Adenosylhomocysteine) is an amino acid derivative and a modulartor in several metabolic pathways. It is an intermediate in the synthesis of cysteine and adenosine[1]. SAH is an inhibitor for METTL3-METTL14 heterodimer complex (METTL3-14) with an IC50 of 0.9 µM[2].
|
-
- HY-N0325S
-
|
|
Isotope-Labeled Compounds
Parasite
|
Infection
Inflammation/Immunology
|
|
DL-Methionine- 13C is the 13C-labeled DL-Methionine. DL-Methionine is an essential amino acid containing sulfur with oxidative stress defense effects. DL-Methionine can be used for animal natural feed. DL-Methionine also kills H. rostochiensis on potato plants[1][2][3].
|
-
- HY-N0394S3
-
|
|
Endogenous Metabolite
Ferroptosis
|
Others
|
|
L-Cystine- 34S2 is the 34S-labeled L-Cystine. L-Cystine is an amino acid and intracellular thiol, which plays a critical role in the regulation of cellular processes.
|
-
- HY-B0215S1
-
|
N-Acetylcysteine-15N; N-Acetyl-L-cysteine-15N; NAC-15N
|
Isotope-Labeled Compounds
Reactive Oxygen Species
Endogenous Metabolite
Apoptosis
Ferroptosis
Influenza Virus
Disulfidptosis
|
Infection
Neurological Disease
|
|
Acetylcysteine- 15N (N-Acetylcysteine- 15N) is the 15N-labeled Acetylcysteine. Acetylcysteine (N-Acetylcysteine) is a mucolytic agent which reduces the thickness of the mucus. Acetylcysteine is a ROS inhibitor. Acetylcysteine is a cysteine precursor, prevents hemin-induced ferroptosis by neutralizing toxic lipids generated by arachidonate-dependent activity of 5-lipoxygenases. Acetylcysteine induces cell apoptosis. Acetylcysteine also has anti-influenza virus activities. In addition, Acetylcysteine is the most stable form of cysteine during drug delivery and can be used in disulfidptosis studies .
|
-
- HY-13677S1
-
|
Mercaptopurine-13C2,15N; 6-MP-13C2,15N
|
Nucleoside Antimetabolite/Analog
Autophagy
Endogenous Metabolite
|
Cancer
|
|
6-Mercaptopurine- 13C2, 15N is the 13C- and 15N-labeled 6-Mercaptopurine. 6-Mercaptopurine is a purine analogue which acts as an antagonist of the endogenous purines and has been widely used as antileukemic agent and immunosuppressive agent.
|
-
- HY-15129S
-
|
L-Serine O-phosphate-13C3,15N; L-SOP-13C3,15N
|
mGluR
Endogenous Metabolite
|
Neurological Disease
|
|
O-Phospho-L-serine- 13C3, 15N is the 13C- and 15N-labeled O-Phospho-L-serine. O-Phospho-L-serine is the immediate precursor to L-serine in the serine synthesis pathway, and an agonist at the group III mGluR receptors (mGluR4, mGluR6, mGluR7, and mGluR8); O-Phospho-L-serine also acts as a weak antagonist for mGluR1 and a potent antagonist for mGluR2[1].
|
-
- HY-N0390S10
-
|
L-Glutamic acid 5-amide-1,2-13C2
|
Isotope-Labeled Compounds
mGluR
Endogenous Metabolite
Ferroptosis
|
Metabolic Disease
|
|
L-Glutamine-1,2- 13C2 is the 13C-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells[1][2].
|
-
- HY-N0390S11
-
-
- HY-D0187S
-
-
- HY-I0096S
-
-
- HY-W015466S
-
-
- HY-W134007S1
-
-
- HY-100532S
-
-
- HY-113365S1
-
|
4-Cholesten-3-one-13C
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Cholestenone- 13C is the 13C labeled Cholestenone. Cholestenone (4-Cholesten-3-one), the intermediate oxidation product of cholesterol, is metabolized primarily in the liver. Cholestenone is highly mobile in membranes and influences cholesterol flip-flop and efflux. Cholestenone may cause long-term functional defects in cells[1][2][3].
|
-
- HY-113365S2
-
|
4-Cholesten-3-one-13C2
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Metabolic Disease
|
|
Cholestenone- 13C2 is the 13C labeled Cholestenone. Cholestenone (4-Cholesten-3-one), the intermediate oxidation product of cholesterol, is metabolized primarily in the liver. Cholestenone is highly mobile in membranes and influences cholesterol flip-flop and efflux. Cholestenone may cause long-term functional defects in cells[1][2][3].
|
-
- HY-13458S1
-
|
L-DOPS-13C2,15N hydrochloride; DOPS-13C2,15N hydrochloride; SM5688-13C2,15N hydrochloride
|
Adrenergic Receptor
Isotope-Labeled Compounds
|
Neurological Disease
|
|
Droxidopa- 13C2, 15N (hydrochloride) is deuterium labeled Droxidopa. Droxidopa(L-DOPS), the mixture of Droxidopa (w/w80%) and Pharmaceutical starch (w/w20%), acts as a proagent to the neurotransmitters norepinephrine (noradrenaline) and epinephrine (adrenaline); Droxidopa(L-DOPS) is capable of crossing the protective blood–brain barrier[1][2].
|
-
- HY-137912S1
-
-
- HY-144153S
-
-
- HY-41121S4
-
-
- HY-B1732S3
-
-
- HY-N0322S8
-
|
|
Isotope-Labeled Compounds
Estrogen Receptor/ERR
Endogenous Metabolite
|
Metabolic Disease
|
|
Cholesterol- 18O is the deuterium labeled Cholesterol. Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins . Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist .
|
-
- HY-W004260S3
-
|
Icosanoic acid-13C
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Cancer
|
|
Arachidic acid- 13C is the 13C labeled Arachidic acid. Arachidic acid (Icosanoic acid), a long-chain fatty acid, is present in all mammalian cells, typically esterified to membrane phospholipids, and is one of the most abundant polyunsaturated fatty acids present in human tissue .
|
-
- HY-W007720S1
-
-
- HY-W013061S5
-
-
- HY-W014223S
-
|
Ultraviolet absorber UV-0-13C6
|
Isotope-Labeled Compounds
|
Others
|
|
2,4-Dihydroxybenzophenone- 13C6 (Ultraviolet absorber UV-0- 13C6) is the 13C- and deuterium labeled (2,4-Dihydroxyphenyl)(phenyl)methanone[1].
|
-
- HY-Y0366S4
-
-
- HY-N0229S15
-
|
L-2-Aminopropionic acid-13C2,15N
|
Endogenous Metabolite
|
Metabolic Disease
|
|
L-Alanine- 13C2, 15N is the 13C- and 15N-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.
|
-
- HY-100354S
-
-
- HY-101064S
-
|
|
PPAR
|
Others
|
|
Fmoc-leucine- 13C is a 13C-labeled Boc-Glycine[1].
|
-
- HY-101064S1
-
|
|
Isotope-Labeled Compounds
PPAR
|
Metabolic Disease
|
|
Fmoc-leucine- 13C6, 15N is a 15N-labeled and 13C-labled Fmoc-leucine. Fmoc-leucine is a selective PPARγ modulator. Fmoc-leucine activates PPARγ with a lower potency but a similar maximal efficacy than rosiglitazone. Fmoc-leucine improves insulin sensitivity
|
-
- HY-101064S4
-
-
- HY-128790S1
-
|
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Metabolic Disease
|
|
4-Methoxyestrone- 13C6 is a 13C-labeled 5'-Guanylic acid. 5'-Guanylic acid (5'-GMP) is involved in several metabolic disorders, including the AICA-ribosiduria pathway, adenosine deaminase deficiency, adenine phosphoribosyltransferase deficiency (aprt), and
|
-
- HY-141578S
-
-
- HY-141901S2
-
-
- HY-143857S
-
-
- HY-143876S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
L-Argininosuccinic acid- 13C6, 15N4 (barium, dihydrate) is a 15N-labeled and 13C-labled labeled L-Argininosuccinic acid (barium, dihydrate)[1].
|
-
- HY-144085S
-
-
- HY-144344S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
Benzyl(2R)-3-N,N-dibenzylamino-2-fluoropropanoate- 13C3 is a 13C-labeled and deuterium labeled Benzyl(2R)-3-N,N-dibenzylamino-2-fluoropropanoate[1].
|
-
- HY-144345S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
L-GAMMA-glutamyl-L-cysteinyl-L-lysine- 13C5, 15N is a 15N-labeled and 13C-labled labeled L-GAMMA-glutamyl-L-cysteinyl-L-lysine[1].
|
-
- HY-144348S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
N-[4-(2-Pyridinyl)benzoyl]glycine- 13C2, 15N is a 15N-labeled and 13C-labled labeled N-[4-(2-Pyridinyl)benzoyl]glycine[1].
|
-
![N-[4-(2-Pyridinyl)benzoyl]glycine-13C2,15N](//file.medchemexpress.eu/product_pic/hy-144348s.gif)
- HY-144418S
-
-
- HY-144432S
-
-
- HY-146708S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
((2R,3S,4R,5R)-5-(2-Amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate- 15N4 (sodium) is a 15N-labeled ((2R,3S,4R,5R)-5-(2-Amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate (so
|
-
- HY-41121S1
-
-
- HY-41121S2
-
-
- HY-76204S
-
-
- HY-76204S1
-
-
- HY-79128S
-
-
- HY-79131S
-
-
- HY-79131S1
-
-
- HY-79131S3
-
-
- HY-79576S2
-
|
Oestrone methyl ether-13C6; 3-O-Methylestrone-13C6
|
Isotope-Labeled Compounds
|
Others
|
|
Estrone 3-methyl ether- 13C6 is a 13C-labeled 3-(4-Chlorophenyl)-1-methoxy-1-methylurea[1].
|
-
- HY-I1111S1
-
-
- HY-I1111S2
-
-
- HY-I1111S3
-
-
- HY-I1111S4
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
Fmoc-L-Val-OH- 15N is a 15N-labeled Leucomalachite green. Leucomalachite green is a triphenylmethane dye used to detect blood. Leucomalachite green, a major metabolite of malachite green, is a potential carcinogen, teratogen and mutagen[1][2].
|
-
- HY-N0091S
-
-
- HY-N0091S1
-
|
Purin-6-o-13C,15N2; Sarcine-13C,15N2
|
Bacterial
|
Infection
|
|
Hypoxanthine- 13C, 15N2 is a 15N-labeled and 13C-labled Furaltadone. Furaltadone, a nitrofuran agent, has the potential for the study in infections of chickens with salmonella enteritidis. Furaltadone is inhibitory and bactericidal in vitro for staphylococci
|
-
- HY-N0091S2
-
-
- HY-N0091S3
-
-
- HY-N0091S4
-
-
- HY-W002327S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
Fmoc-Asn(Trt)-OH- 13C4, 15N2 is a 15N-labeled and 13C-labled 4-(4-(tert-Butyl)-2-ethoxyphenyl)-2-(2,6-difluorophenyl)-4,5-dihydrooxazole[1].
|
-
- HY-W002327S1
-
-
- HY-W007706S
-
-
- HY-W007798S
-
-
- HY-W007941S
-
-
- HY-W008016S
-
-
- HY-W008371S1
-
-
- HY-W008621S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
Oleic acid- 13C (potassium) is a 13C-labeled (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-oxo-4-(tritylamino)butanoic acid[1].
|
-
- HY-W009204S4
-
-
- HY-W009204S5
-
|
|
Isotope-Labeled Compounds
PPAR
|
Metabolic Disease
|
|
Fmoc-Ala-OH- 13C3 is a 13C-labeled Fmoc-leucine. Fmoc-leucine is a selective PPARγ modulator. Fmoc-leucine activates PPARγ with a lower potency but a similar maximal efficacy than rosiglitazone. Fmoc-leucine improves insulin sensitivity in normal, diet-ind
|
-
- HY-W009300S1
-
-
- HY-W009762S
-
-
- HY-W009762S1
-
-
- HY-W009762S6
-
-
- HY-W009762S7
-
-
- HY-W010209S
-
-
- HY-W010209S1
-
-
- HY-W011012S
-
-
- HY-W013780S
-
|
|
Isotope-Labeled Compounds
Autophagy
Bacterial
Antibiotic
|
Infection
|
|
Fmoc-Pro-OH-1- 13C is a 13C-labeled Sulfabenzamide. Sulfabenzamide (N-Sulfanilylbenzamide) is an antimicrobial agent and usually consumed in combination with Sulfathiazole and Sulfacetamide. Sulfabenzamide is effective against Gram-positive and negative ba
|
-
- HY-W013780S1
-
|
|
Isotope-Labeled Compounds
Fungal
|
Infection
|
|
Fmoc-Pro-OH- 13C5, 15N is a 15N-labeled and 13C-labled Pyrimethanil. Pyrimethanil is an anilinopyrimidine and broad-spectrum contact fungicide for the control of Botrytis spp. on a wide variety of crops[1]. Pyrimethanil inhibits the biosynthesis of methioni
|
-
- HY-W013780S2
-
-
- HY-W015339S
-
-
- HY-W017389S
-
|
|
Isotope-Labeled Compounds
|
Cancer
|
|
Xanthine- 13C, 15N2 is a 15N-labeled and 13C-labled Xanthine (HY-W017389). Xanthine is a plant alkaloid with mild stimulant activity of the central nervous system. Xanthine also acts as an intermediate product on the pathway of purine degradation .
|
-
- HY-W018386S
-
-
- HY-W101495S
-
-
- HY-W134007S
-
-
- HY-Y0134S
-
-
- HY-Y0978S2
-
|
N-tert-Butoxycarbonyl-2-aminoacetic acid-2-13C; NSC 127669-2-13C
|
Isotope-Labeled Compounds
Androgen Receptor
|
Endocrinology
|
|
Boc-Glycine-2- 13C is a 13C-labeled Linuron. Linuron is a phenylurea herbicide that is widely used to control the growth of grass and weeds in various agriculture crops and in orchards. Linuron is a photosystem II inhibitor. Linuron is also a competitive a
|
-
- HY-Y0978S3
-
-
- HY-Y1250S3
-
-
- HY-Y1250S4
-
|
|
Fungal
|
Infection
Cancer
|
|
Fmoc-Gly-OH-1- 13C is a 13C-labeled Carbendazim. Carbendazim is a potent and orally active broad-spectrum benzimidazole fungicide and can be acts as a pesticide for fungal diseases research, such as Seproria, Fusarium and Sclerotina[1][3]. Carbendazim is a
|
-
- HY-Y1250S5
-
-
- HY-Y1250S6
-
|
Fmoc glycine-13C2,15N; N-(9-Fluorenylmethoxycarbonyl)glycine-13C2,15N; N-Fluorenylmethoxycarbonylglycine-13C2,15N; NPC 14692-13C2-15N; NSC 334288-13C2,15N; [[[(9H-Fluoren-9-yl)methoxy]carbonyl]amino]acetic acid-13C2,15N
|
Isotope-Labeled Compounds
Influenza Virus
Bacterial
|
Infection
|
|
Fmoc-Gly-OH- 13C2, 15N is a 15N-labeled and 13C-labled Crystal Violet. Crystal violet (Basic Violet 3) is a triarylmethane dye. Crystal Violet (Gentian Violet) has antiviral effects against H1N1 and also has prominent bactericidal activities.
|
-
- HY-112019
-
|
|
Endogenous Metabolite
|
Others
|
|
L-Methionine- 34S is a 34S-labeled L-Methionine. L-Methionine is the L-isomer of Methionine, an essential amino acid for human development. Methionine acts as a hepatoprotectant.
|
-
- HY-B0035S2
-
-
- HY-Y0479AS
-
-
- HY-112586S1
-
|
|
Isotope-Labeled Compounds
Bacterial
Antibiotic
|
Infection
|
|
Sulfaethoxypyridazine- 13C6 is the 13C6 labeled Sulfaethoxypyridazine. Sulfaethoxypyridazine is a sulfonamide antibacterial agent. Sulfaethoxypyridazine is a sulfonamide that is used in veterinary medicine as feedstuffs.
|
-
- HY-114750S
-
|
|
Isotope-Labeled Compounds
Drug Metabolite
|
Others
|
|
Mebendazole-amine- 13C6 is the 13C6 labeled Mebendazole-amine. Mebendazole-amine is a metabolite of Mebendazole. Mebendazole is a broad-spectrum benzimidazole anti-helminthic agent.
|
-
- HY-116214S1
-
|
|
Isotope-Labeled Compounds
Fungal
Androgen Receptor
|
Infection
Endocrinology
|
|
Cyprodinil- 13C6 is the 13C6 labeled Cyprodinil. Cyprodinil is an anilinopyrimidine broad-spectrum fungicide that inhibits the biosynthesis of methionine in phytopathogenic fungi. Cyprodinil inhibits mycelial cell growth of B. cinerea, P. herpotrichoides, and H. oryzae on amino acid-free media (IC50s=0.44, 4.8, and 0.03 µM, respectively). Cyprodinil acts as an androgen receptor (AR) agonist (EC50=1.91 µM) in the absence of the AR agonist DHT and inhibits the androgenic effect of DHT (IC50=15.1 µM).
|
-
- HY-117275S1
-
|
Meclofenamate-13C6
|
Isotope-Labeled Compounds
Gap Junction Protein
Endogenous Metabolite
|
Inflammation/Immunology
|
|
Meclofenamic acid- 13C6 is the 13C6 labeled Meclofenamic acid. Meclofenamic Acid (Meclofenamate), a non-steroidal, anti-inflammatory agent, is a highly selective fat mass and obesity-associated (FTO) enzyme inhibitor. Meclofenamic Acid competes with FTO binding for the m(6)A-containing nucleic acid. Meclofenamic acid is a non-selective gap-junction blocker.
|
-
- HY-12542S
-
|
F 368-13C3
|
Isotope-Labeled Compounds
Glutathione Reductase
|
Neurological Disease
Inflammation/Immunology
|
|
Dantrolene- 13C3 is the 13C3 labeled Dantrolene. Dantrolene (F368), a muscle relaxant, non-competitively inhibits human erythrocyte glutathione reductase. Ki and IC50 values are 111.6 μM and 52.3 μM, respectively. Dantrolene is a ryanodine receptor antagonist and Ca2+ signaling stabilizer. Dantrolene can be used for the research of muscle spasticity, malignant hyperthermia, Huntington's disease and other neuroleptic malignant syndrome.
|
-
- HY-133694S
-
|
|
Isotope-Labeled Compounds
Drug Metabolite
|
Others
|
|
2-Aminoflubendazole- 13C6 is the 13C6 labeled 2-Aminoflubendazole. 2-Aminoflubendazole is the metabolite of Benzimidazoles. Benzimidazoles (BZ) are a class of agents with activities against fungi, protozoa, and helminthes.
|
-
- HY-138538S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
2-Nitrobenzaldehyde semicarbazone- 13C, 15N2-1 is the 13C, 15N labeled 2-Nitrobenzaldehyde semicarbazone. 2-Nitrobenzaldehyde Semicarbazone is a derivative of Semicarbazide. 2-Nitrobenzaldehyde Semicarbazone can be measured as a metabolite marker to detect the widely banned antibiotic Nitrofurazone.
|
-
- HY-14538S3
-
-
- HY-146785S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
1-Palmitoyl-2-hydroxy-sn-glycero-3-phosphate- 13C16 (sodium) is 13C16 labeled 1-Palmitoyl-2-hydroxy-sn-glycero-3-phosphate.
|
-
- HY-N0684S3
-
-
- HY-146944S
-
-
- HY-146966S
-
-
- HY-146967S
-
-
- HY-146968S
-
-
- HY-146969S
-
-
- HY-146972S
-
-
- HY-146975S
-
-
- HY-146976S
-
-
- HY-15036S1
-
|
|
Isotope-Labeled Compounds
COX
Apoptosis
|
Inflammation/Immunology
|
|
Diclofenac- 13C6 is the 13C6 labeled Diclofenac. Diclofenac is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells, and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively. Diclofenac induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade.
|
-
- HY-15037S2
-
|
GP 45840-13C6
|
Isotope-Labeled Compounds
COX
Apoptosis
|
Inflammation/Immunology
|
|
Diclofenac- 13C6 (Sodium) is the 13C6 labeled Diclofenac (Sodium). Diclofenac Sodium (GP 45840) is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells, and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively. Diclofenac Sodium induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade.
|
-
- HY-17453S1
-
|
GR 33343X-13C6 xinafoate
|
Isotope-Labeled Compounds
Adrenergic Receptor
|
Inflammation/Immunology
Endocrinology
|
|
Salmeterol- 13C6 (xinafoate) is the 13C6 labeled Salmeterol (xinafoate). Salmeterol (GR 33343X) xinafoate is a potent and selective human β2 adrenoceptor agonist. Salmeterol shows potent stimulation of cAMP accumulation in CHO cells expressing human β2, β1 and β3 adrenoceptors with pEC50s of 9.6, 6.1, and 5.9, respectively.
|
-
- HY-17596S
-
|
|
Isotope-Labeled Compounds
Parasite
|
Infection
|
|
Closantel- 13C6 is the 13C6 labeled Closantel. Closantel is a halogenated salicylanilide with a potent anti-parasitic activity. Closantel is a potent and highly specific Onchocerca volvulus chitinase (OvCHT1) inhibitor with an IC50 of 1.6 μM and a Ki of 468 nM. Closantel inhibits the O. volvulus L3 to L4 molt of developing.
|
-
- HY-A0253S
-
-
- HY-B0213S1
-
|
Sulfametoxydiazine-13C6; 5-Methoxysulfadiazine-13C6
|
Isotope-Labeled Compounds
Antibiotic
Bacterial
|
Infection
|
|
Sulfameter- 13C6 is the 13C6 labeled Sulfameter. Sulfameter (Sulfametoxydiazine; 5-Methoxysulfadiazine) is an effective long-acting sulfonamide antibiotic with antibacterial activities. Sulfameter can be used for the research of urinary tract infections and lepriasis.
|
-
- HY-B0230S2
-
|
|
COX
|
Inflammation/Immunology
|
|
Phenylbutazone- 13C12 is the 13C12 labeled Phenylbutazone. Phenylbutazone is an efficient reducing cofactor for the peroxidase activity of prostaglandin H synthase (PHS). Phenylbutazone, a hepatotoxin, is a nonsteroidal anti-inflammatory agent (NSAID). Phenylbutazone induces muscle blind-like protein 1 (MBNL1) expression and has the potential for ankylosing spondylitis research.
|
-
- HY-B0263S1
-
-
- HY-B0335S1
-
|
GEA 6414-13C6
|
Isotope-Labeled Compounds
COX
|
Inflammation/Immunology
Cancer
|
|
Tolfenamic acid- 13C6 is the 13C6 labeled Tolfenamic acid. Tolfenamic Acid (GEA 6414) is a non-steroidal anti-inflammatory and anti-cancer agent, selectively inhibits COX-2, with an IC50 of 13.49 μM (3.53 μg/mL) in LPS-treated (COX-2) canine DH82 monocyte/macrophage cells, but shows no effect on COX-1.
|
-
- HY-B0467AS
-
-
- HY-B0493S1
-
-
- HY-B0497S1
-
|
BAY2353-13C6
|
Isotope-Labeled Compounds
STAT
Parasite
Antibiotic
|
Infection
Cancer
|
|
Niclosamide- 13C6 is the 13C6 labeled Niclosamide. Niclosamide (BAY2353) is an orally bioavailable chlorinated salicylanilide, with anthelmintic and potential antineoplastic activity. Niclosamide (BAY2353) inhibits STAT3 with IC50 of 0.25 μM in HeLa cells and inhibits DNA replication in a cell-free assay.
|
-
- HY-B0503S
-
|
Thiouracil-13C,15N2
|
Isotope-Labeled Compounds
NO Synthase
|
Endocrinology
Cancer
|
|
2-Thiouracil- 13C, 15N2 is the 13C, 15N labeled 2-Thiouracil. 2-Thiouracil (Thiouracil) is an antithyroid compound. 2-Thiouracil can function as a highly specific melanoma seeker. 2-Thiouracil is a selective inhibitor of neuronal nitric oxide synthase (nNOS) with a Ki of 20 μM.
|
-
- HY-B0508S1
-
-
- HY-B0526S
-
-
- HY-B0688S2
-
|
4,4′-Diaminodiphenyl sulfone-13C12; DDS-13C12
|
Isotope-Labeled Compounds
Antibiotic
Parasite
Bacterial
Reactive Oxygen Species
|
Infection
Inflammation/Immunology
|
|
Dapsone- 13C12 is the 13C12 labeled Dapsone (HY-B0688). Dapsone (4,4′-Diaminodiphenyl sulfone) is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities. Dapsone exerts effective antileprosy activity and inhibits folate synthesis in cell extracts of M. leprae. Dapsone is used for dermatologic disorder research, including leprosy, dermatitis herpetiformis, acne vulgaris et al .
|
-
- HY-B0925S
-
-
- HY-B0946S2
-
|
|
Isotope-Labeled Compounds
Bacterial
Antibiotic
|
Infection
|
|
Sulfamonomethoxine- 13C6 is the 13C6 labeled Sulfamonomethoxine. Sulfamonomethoxine is a long acting sulfonamide antibacterial agent, used in blood kinetic studies,and blocks the synthesis of folic acid by inhibiting synthetase of dihydropteroate.
|
-
- HY-B0947S1
-
|
|
Isotope-Labeled Compounds
Bacterial
|
Infection
|
|
Sulfanitran- 13C6 is the 13C labeled Sulfanitran. Sulfanitran is an antibacterial and anticoccidial agent used in poultry feeds. Sulfanitran also is a multidrug resistance protein 2 (MRP2) stimulator that can increase the affinity of MRP2 for estradiol-17-β-D-glucuronide (E217βG).
|
-
- HY-B0975S
-
|
Phenoxymethylpenicillin-13C6 potassium salt
|
Isotope-Labeled Compounds
Bacterial
Antibiotic
|
Infection
|
|
Penicillin V- 13C6 (potassium) is the 13C6 labeled Penicillin V (potassium). Penicillin V Potassium (Phenoxymethylpenicillin potassium salt) is an orally active antibiotic. Penicillin V Potassium inhibits the growth of Streptococci, C. difficile and S. aureus. Penicillin V Potassium can be used for the research of otitis, sinusitis, pharyngitis and tonsillitis.
|
-
- HY-B1118S1
-
|
RP-14539-13C2, 15N2; PM-185184-13C2, 15N2
|
Isotope-Labeled Compounds
Parasite
Antibiotic
|
Infection
|
|
Secnidazole- 13C2, 15N2 is the 13C2, 15N2 labeled Secnidazole. Secnidazole (RP-14539;PM-185184) is an orally active azole antibiotic with a longer half-life than metronidazole (HY-B0318). Secnidazole is against the vaginosis-associated bacteria and has the potential for bacterial vaginosis research.
|
-
- HY-B1221S1
-
|
|
Isotope-Labeled Compounds
COX
AMPK
Potassium Channel
Chloride Channel
Calcium Channel
Parasite
|
Inflammation/Immunology
|
|
Flufenamic acid- 13C6 is the 13C6 labeled Flufenamic acid. Flufenamic acid is a non-steroidal anti-inflammatory agent, inhibits cyclooxygenase (COX), activates AMPK, and also modulates ion channels, blocking chloride channels and L-type Ca 2+ channels, modulating non-selective cation channels (NSC), activating K+ channels. Flufenamic acid binds to the central pocket of TEAD2 YBD and inhibits both TEAD function and TEAD-YAP-dependent processes, such as cell migration and proliferation.
|
-
- HY-B1267S1
-
|
|
Isotope-Labeled Compounds
Bacterial
Antibiotic
|
Infection
|
|
Sulfaguanidine- 13C6 is the 13C6 labeled Sulfaguanidine. Sulfaguanidine is an orally active antimicrobial agent/antibiotic of sulfonamide class. Sulfaguanidine can be used for the research of enteric infections such as bacillary dysentery.
|
-
- HY-B1331S1
-
|
Cyromazin-13C3; CGA-72662-13C3
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Neurological Disease
|
|
Cyromazine- 13C3 is the 13C3 labeled Cyromazine. Cyromazine is a triazine insect growth regulator used as an insecticide and an acaricide. It is a cyclopropyl derivative of melamine. Cyromazine works by affecting the nervous system of the immature larval stages of certain insects.
|
-
- HY-B1355AS1
-
-
- HY-B1436S1
-
-
- HY-B1703S
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Nifursol- 13C6 is the 13C6 labeled Nifursol. Nifursol is a potent and orally active veterinary antibiotic for the prevention of histomoniasis. Nifursol rapidly metabolizes to form the metabolic marker 3,5-dinitrosalicyclic acid hydrazide (DNSAH) which can persist for a long time. Nifursol is widely used for the research of Escherichia Gastroenteropathy in poultry, fowl and aquatic animal.
|
-
- HY-B1781S
-
|
Sulfachlorpyridazine-13C6
|
Isotope-Labeled Compounds
Bacterial
Antibiotic
|
Infection
|
|
Sulfachloropyridazine- 13C6 is the 13C6 labeled Sulfachloropyridazine. Sulfachloropyridazine is a broad spectrum sulfonamide used against both Gram-positive and Gram-negative aerobic bacteria.
|
-
- HY-N7123S1
-
-
- HY-N7398S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
2-Pentylfuran- 13C2 is the 13C2 labeled 2-Pentylfuran. 2-Pentylfuran is the compound isolated from steam volatile oils obtained from potatoes at atmospheric pressure.
|
-
- HY-W010421S
-
-
- HY-W012478S
-
-
- HY-W014225S
-
-
- HY-W017529S
-
-
- HY-W020772AS
-
-
- HY-W020772AS1
-
-
- HY-W020772S
-
-
- HY-W020772S1
-
-
- HY-W069721S1
-
-
- HY-W111879S
-
-
- HY-W156511S
-
-
- HY-W278861S
-
-
- HY-W280531S
-
-
- HY-Y0674S
-
-
- HY-N0771S9
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
L-Isoleucine- 13C6, 15N is 13C and 15N labeled L-isoleucine. L-isoleucine is a nonpolar hydrophobic amino acid[1]. L-Isoleucine is an essential amino acid.
|
-
- HY-B0167S1
-
-
- HY-W242887S2
-
-
- HY-B0400AS
-
-
- HY-B1659AS
-
-
- HY-B0400AS1
-
-
- HY-W145612S
-
-
- HY-W145652S
-
-
- HY-W145652S1
-
-
- HY-W012584S
-
-
- HY-W012584S1
-
-
- HY-146989S
-
-
- HY-116956S
-
-
- HY-116956S1
-
-
- HY-116956S2
-
-
- HY-116956S3
-
-
- HY-N7092AS
-
-
- HY-106950CS
-
-
- HY-106950CS1
-
-
- HY-106950CS3
-
-
- HY-W142434S
-
-
- HY-W039909S
-
-
- HY-W039909S1
-
-
- HY-N6614S1
-
-
- HY-141637S
-
-
- HY-146990S
-
-
- HY-146992S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
α-D-Glucopyranosyl 1-phosphate- 13C (dicyclohexylamine, monohydrate) is the 13C labeled α-D-Glucopyranosyl 1-phosphate[1].
|
-
- HY-146993S
-
-
- HY-34628S
-
-
- HY-34628S1
-
-
- HY-34628S2
-
-
- HY-W008507S
-
-
- HY-146995S
-
-
- HY-146995S1
-
-
- HY-W242887S3
-
-
- HY-146994S
-
-
- HY-146994S1
-
-
- HY-146994S2
-
-
- HY-N0059AS
-
-
- HY-N0059AS1
-
-
- HY-146996S
-
-
- HY-W016508S1
-
-
- HY-114364S
-
-
- HY-W338294S
-
|
Deoxycytidine-13C (monohydrate); Cytosine deoxyriboside-13C (monohydrate); Deoxyribose cytidine-13C (monohydrate)
|
Endogenous Metabolite
|
Others
|
|
2'-Deoxycytidine- 13C (monohydrate) is the 13C labeled 2'-Deoxycytidine[1].
|
-
- HY-W338294S1
-
|
Deoxycytidine-13C-2 (monohydrate); Cytosine deoxyriboside-13C-2 (monohydrate); Deoxyribose cytidine-13C-2 (monohydrate)
|
Endogenous Metabolite
|
Others
|
|
2'-Deoxycytidine- 13C-2 (monohydrate) Monohydrate is the 13C labeled 2'-Deoxycytidine[1].
|
-
- HY-W338294S2
-
|
Deoxyguanosine-13C (monohydrate); Guanine deoxyriboside-13C (monohydrate)
|
Endogenous Metabolite
|
Others
|
|
2'-Deoxyguanosine- 13C (monohydrate) Monohydrate is the 13C labeled 2'-Deoxyguanosine[1].
|
-
- HY-N0090S
-
-
- HY-W007928S
-
-
- HY-W007928S1
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
1-O-Acetyl 2,3,5-tri-O-benzoyl-beta-D-ribofuranoside- 13C-1 is the 13C labeled 1-O-Acetyl-2,3,5-Tri-O-benzoyl-beta-D-Ribofuranose[1].
|
-
- HY-W145492S2
-
-
- HY-W145492S3
-
-
- HY-146986S1
-
-
- HY-W012864S
-
-
- HY-W012864S1
-
-
- HY-W012864S2
-
-
- HY-146279S
-
-
- HY-W015198S
-
-
- HY-128748S
-
-
- HY-128748S1
-
-
- HY-128741S
-
-
- HY-128741S1
-
-
- HY-128741S2
-
-
- HY-N2353S
-
|
(±)-Arabinose-1-13C; DL-Arabinose-1-13C
|
Endogenous Metabolite
|
Others
|
|
Arabinose-1- 13C is the 13C labeled Arabinose. Arabinose is an endogenous metabolite[1].
|
-
- HY-N0059S3
-
-
- HY-N0059S
-
-
- HY-N0059S1
-
-
- HY-N0059S2
-
-
- HY-128417S1
-
-
- HY-N2325S
-
-
- HY-N7092S4
-
|
D(-)-Fructose-3-13C
|
Endogenous Metabolite
|
Others
|
|
D-Fructose-3- 13C is the 13C labeled D-Fructose. D-Fructose (D(-)-Fructose) is a naturally occurring monosaccharide found in many plants[1].
|
-
- HY-N7092S5
-
-
- HY-N7092S6
-
-
- HY-N7092S7
-
|
D(-)-Fructose-6-13C
|
Endogenous Metabolite
|
Others
|
|
D-Fructose-6- 13C is the 13C labeled D-Fructose. D-Fructose (D(-)-Fructose) is a naturally occurring monosaccharide found in many plants[1].
|
-
- HY-33212S
-
-
- HY-128753S3
-
-
- HY-128753S4
-
-
- HY-128753S5
-
-
- HY-W011683S
-
-
- HY-W011683S1
-
-
- HY-W011683S2
-
-
- HY-W011683S3
-
-
- HY-77956S
-
-
- HY-77956S1
-
|
Deoxyribose-13C-1
|
Endogenous Metabolite
|
Others
|
|
Thyminose- 13C-1 is the 13C labeled Thyminose. Thyminose is an endogenous metabolite[1].
|
-
- HY-77956S2
-
|
Deoxyribose-13C-2
|
Endogenous Metabolite
|
Others
|
|
Thyminose- 13C-2 is the 13C labeled Thyminose. Thyminose is an endogenous metabolite[1].
|
-
- HY-W040240S
-
|
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Others
|
|
(3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one- 13C is the 13C labeled (3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one. (3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one is an endogenous metabolite[1].
|
-
- HY-W040240S1
-
|
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Others
|
|
(3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one- 13C-1 is the 13C labeled (3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one. (3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one is an endogenous metabolite[1].
|
-
- HY-W040240S2
-
|
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Others
|
|
(3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one- 13C-2 is the 13C labeled (3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one. (3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one is an endogenous metabolite[1].
|
-
- HY-N7092S20
-
-
- HY-N7092S21
-
-
- HY-B1449S1
-
-
- HY-B1449S2
-
-
- HY-B1449S3
-
-
- HY-B1449S4
-
-
- HY-B0389S29
-
|
Glucose-18O; D-(+)-Glucose-18O; Dextrose-18O
|
Endogenous Metabolite
|
Metabolic Disease
Cancer
|
|
D-Glucose- 18O is the 18O labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules
|
-
- HY-B0389S30
-
|
Glucose-18O-1; D-(+)-Glucose-18O-1; Dextrose-18O-1
|
Endogenous Metabolite
|
Metabolic Disease
Cancer
|
|
D-Glucose- 18O-1 is the 18O labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecule
|
-
- HY-B0389S31
-
|
Glucose-18O-2; D-(+)-Glucose-18O-2; Dextrose-18O-2
|
Endogenous Metabolite
|
Metabolic Disease
Cancer
|
|
D-Glucose- 18O-2 is the 18O labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecule
|
-
- HY-B0389S32
-
|
Glucose-18O-3; D-(+)-Glucose-18O-3; Dextrose-18O-3
|
Endogenous Metabolite
|
Metabolic Disease
Cancer
|
|
D-Glucose- 18O-3 is the 18O labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecule
|
-
- HY-A0132S4
-
-
- HY-N0379S2
-
-
- HY-W018772S
-
-
- HY-113216S
-
-
- HY-N2840S
-
|
Allodulcitol-13C
|
Isotope-Labeled Compounds
|
Metabolic Disease
Cancer
|
|
Allitol- 13C is the 13C labeled Allitol. Allitol is a rare natural polyol that can be used as a sweetener. Allitol is an important intermediate for the preparation of the agents which against diabetes, cancer, and viral infections, including AIDS[1]
|
-
- HY-N3686S
-
-
- HY-N3686S1
-
-
- HY-N3686S2
-
-
- HY-Y0418S
-
-
- HY-Y0418S1
-
-
- HY-Y0418S2
-
-
- HY-Y0418S3
-
-
- HY-B0400S2
-
|
Sorbitol-13C-1; D-Glucitol-13C-1
|
Endogenous Metabolite
|
Others
|
|
D-Sorbitol- 13C-1 is the 13C labeled D-Sorbitol. D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and dietary
|
-
- HY-B0400S3
-
|
Sorbitol-13C-2; D-Glucitol-13C-2
|
Endogenous Metabolite
|
Others
|
|
D-Sorbitol- 13C-2 is the 13C labeled D-Sorbitol. D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and dietary
|
-
- HY-N0538S
-
-
- HY-N0538S1
-
-
- HY-N0538S2
-
-
- HY-N1480S
-
|
6-Desoxygalactose-13C; L-(-)-Fucose-13C; L-Galactomethylose-13C
|
Isotope-Labeled Compounds
Endogenous Metabolite
Parasite
|
Infection
Metabolic Disease
|
|
(-)-Fucose- 13C is the 13C labeled (-)-Fucose. (-)-Fucose is classified as a member of the hexoses, plays a role in A and B blood group antigen substructure determination, selectin-mediated leukocyte-endothelial adhesion, and host-microbe interacti[1]
|
-
- HY-N1480S1
-
|
6-Desoxygalactose-13C-1; L-(-)-Fucose-13C-1; L-Galactomethylose-13C-1
|
Isotope-Labeled Compounds
Endogenous Metabolite
Parasite
|
Infection
Metabolic Disease
|
|
(-)-Fucose- 13C-1 is the 13C labeled (-)-Fucose. (-)-Fucose is classified as a member of the hexoses, plays a role in A and B blood group antigen substructure determination, selectin-mediated leukocyte-endothelial adhesion, and host-microbe interacti[
|
-
- HY-N1480S2
-
|
6-Desoxygalactose-13C-2; L-(-)-Fucose-13C-2; L-Galactomethylose-13C-2
|
Isotope-Labeled Compounds
Endogenous Metabolite
Parasite
|
Infection
Metabolic Disease
|
|
(-)-Fucose- 13C-2 is the 13C labeled (-)-Fucose. (-)-Fucose is classified as a member of the hexoses, plays a role in A and B blood group antigen substructure determination, selectin-mediated leukocyte-endothelial adhesion, and host-microbe interacti[
|
-
- HY-N1480S3
-
|
6-Desoxygalactose-13C-3; L-(-)-Fucose-13C-3; L-Galactomethylose-13C-3
|
Isotope-Labeled Compounds
Endogenous Metabolite
Parasite
|
Infection
Metabolic Disease
|
|
(-)-Fucose- 13C-3 is the 13C labeled (-)-Fucose. (-)-Fucose is classified as a member of the hexoses, plays a role in A and B blood group antigen substructure determination, selectin-mediated leukocyte-endothelial adhesion, and host-microbe interacti[
|
-
- HY-139312S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
L-Mannitol-1- 13C is the 13C labeled L-Mannitol. L-mannitol is a compound can be used for the compound sweetener synthesis[1][2].
|
-
- HY-113075S
-
-
- HY-113143AS
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Galactose 1-phosphate- 13C (potassium) is the 13C labeled Galactose 1-phosphate Potassium salt. Galactose 1-phosphate Potassium salt is is an intermediate in the galactose metabolism and nucleotide sug[1][2].
|
-
- HY-113143AS1
-
-
- HY-15926S
-
|
2-Nitrophenyl β-D-galactopyranoside-13C
|
Isotope-Labeled Compounds
|
Others
|
|
ONPG- 13C is the 13C labeled ONPG. ONPG is a colorimetric and spectrophotometric substrate for detection of β-galactosidase activit[1][2].
|
-
- HY-A0132S1
-
|
N-Acetyl-2-amino-2-deoxy-D-glucose-13C
|
Endogenous Metabolite
|
Metabolic Disease
|
|
N-Acetyl-D-glucosamine- 13C is the 13C labeled N-Acetyl-D-glucosamine. N-Acetyl-D-Glucosamine (N-Acetyl-2-amino-2-deoxy-D-glucose) is a monosaccharide derivative of gluc[1][2].
|
-
- HY-A0132S2
-
|
N-Acetyl-2-amino-2-deoxy-D-glucose-13C-1
|
Endogenous Metabolite
|
Metabolic Disease
|
|
N-Acetyl-D-glucosamine- 13C-1 is the 13C labeled N-Acetyl-D-glucosamine. N-Acetyl-D-Glucosamine (N-Acetyl-2-amino-2-deoxy-D-glucose) is a monosaccharide derivative of gluc[1][2].
|
-
- HY-A0132S3
-
-
- HY-W010042S
-
-
- HY-W010042S1
-
-
- HY-A0132S5
-
|
N-Acetyl-2-amino-2-deoxy-D-glucose-13C-3
|
Endogenous Metabolite
|
Metabolic Disease
|
|
N-Acetyl-D-glucosamine- 13C-3 is the 13C labeled N-Acetyl-D-glucosamine. N-Acetyl-D-Glucosamine (N-Acetyl-2-amino-2-deoxy-D-glucose) is a monosaccharide derivative of gluc[1][2].
|
-
- HY-I0301S
-
-
- HY-W010042S2
-
-
- HY-N0379S5
-
-
- HY-N0379S6
-
-
- HY-N0379S7
-
-
- HY-N0379S8
-
|
|
Endogenous Metabolite
|
Others
|
|
D-Mannose- 13C-3 is the 13C labeled D-Mannose. D-Mannose is a carbohydrate, which plays an important role in human metabolism, especially in the glycosylationof specific prote[1][2].
|
-
- HY-N0379S9
-
-
- HY-N0379S10
-
-
- HY-B1092AS
-
|
D-Gluconic acid sodium salt-1-13C; Sodium D-gluconate-1-13C; D-Gluconate sodium salt-1-13C
|
Endogenous Metabolite
|
Others
|
|
Gluconate-1- 13C (sodium) is the 13C labeled Gluconate sodi[1][2].
|
-
- HY-112174S
-
|
UDP-α-D-N-Acetylglucosamine-13C disodium
|
Isotope-Labeled Compounds
|
Metabolic Disease
|
|
UDP-GlcNAc- 13C (disodium) is the 13C labeled UDP-GlcNAc Disodium Salt. UDP-GlcNAc Disodium Salt (UDP-α-D-N-Acetylglucosamine Disodium Salt) is a donor substrate of O-GlcNAc transferase (O[1][2].
|
-
- HY-D0186S
-
|
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Infection
|
|
2'-Deoxyuridine-1′- 13C is the 13C labeled 2'-Deoxyuridine. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxud[1]
|
-
- HY-D0186S1
-
|
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Infection
|
|
2'-Deoxyuridine-2′- 13C is the 13C labeled 2'-Deoxyuridine. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxud[1]
|
-
- HY-D0186S2
-
|
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Infection
|
|
2'-Deoxyuridine-3′- 13C is the 13C labeled 2'-Deoxyuridine. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxud[1]
|
-
- HY-D0186S3
-
|
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Infection
|
|
2'-Deoxyuridine-5′- 13C is the 13C labeled 2'-Deoxyuridine. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxud[1]
|
-
- HY-W009444S1
-
-
- HY-W009444S2
-
-
- HY-W009444S3
-
-
- HY-W009444S4
-
-
- HY-W018772S1
-
-
- HY-W018772S2
-
-
- HY-W018772S3
-
-
- HY-W018772S4
-
-
- HY-W018772S5
-
-
- HY-W008351S
-
|
|
Antibiotic
Isotope-Labeled Compounds
|
Cancer
|
|
L-Ribose- 13C is the 13C labeled L-Ribose. L-Ribose, a non-naturally occurring pentose, is an ideal starting material for use in synthesizing L-nucleosides analogues. Many anticancer and antiviral agents are synthesized based on a backbone of L-Ribose and i
|
-
- HY-42680S
-
|
D-(-)-Tagatose-13C
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Metabolic Disease
Cancer
|
|
D-Tagatose- 13C is the 13C labeled D-Tagatose. D-Tagatose (D-(-)-Tagatose) is a rare monosaccharide found in nature with prebiotic characteristics. D-Tagatose is as a substitute for sucrose and a low-calorie sweetener in foodstuffs such as gum, fruit juice
|
-
- HY-42680S1
-
|
D-(-)-Tagatose-13C-1
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Metabolic Disease
Cancer
|
|
D-Tagatose- 13C-1 is the 13C labeled D-Tagatose. D-Tagatose (D-(-)-Tagatose) is a rare monosaccharide found in nature with prebiotic characteristics. D-Tagatose is as a substitute for sucrose and a low-calorie sweetener in foodstuffs such as gum, fruit jui
|
-
- HY-W010256S
-
-
- HY-W010256S1
-
-
- HY-78139S
-
|
L-(-)-Xylose-1-13C
|
Isotope-Labeled Compounds
|
Others
|
|
L-Xylose-1- 13C is the 13C labeled L-Xylose. L-Xylose (L-(-)-Xylose) is the levo-isomer of Xylose. Xylose is classified as a monosaccharide of the aldopentose type[1][2].
|
-
- HY-78139S1
-
|
L-(-)-Xylose-2-13C
|
Isotope-Labeled Compounds
|
Others
|
|
L-Xylose-2- 13C is the 13C labeled L-Xylose. L-Xylose (L-(-)-Xylose) is the levo-isomer of Xylose. Xylose is classified as a monosaccharide of the aldopentose type[1][2].
|
-
- HY-78139S2
-
|
L-(-)-Xylose-5-13C
|
Isotope-Labeled Compounds
|
Others
|
|
L-Xylose-5- 13C is the 13C labeled L-Xylose. L-Xylose (L-(-)-Xylose) is the levo-isomer of Xylose. Xylose is classified as a monosaccharide of the aldopentose type[1][2].
|
-
- HY-A0132S7
-
|
N-Acetyl-2-amino-2-deoxy-D-glucose-15N
|
Endogenous Metabolite
|
Metabolic Disease
|
|
N-Acetyl-D-glucosamine- 15N is the 15N labeled N-Acetyl-D-glucosamine. N-Acetyl-D-Glucosamine (N-Acetyl-2-amino-2-deoxy-D-glucose) is a monosaccharide derivative of gluc[1][2].
|
-
- HY-A0132S8
-
|
N-Acetyl-2-amino-2-deoxy-D-glucose-13C,15N
|
Endogenous Metabolite
|
Metabolic Disease
|
|
N-Acetyl-D-glucosamine- 13C, 15N is the 13C and 15N labeled N-Acetyl-D-glucosamine. N-Acetyl-D-Glucosamine (N-Acetyl-2-amino-2-deoxy-D-glucose) is a monosaccharide derivative of gluc[1][2].
|
-
- HY-A0132S9
-
|
N-Acetyl-2-amino-2-deoxy-D-glucose-13C3,15N
|
Endogenous Metabolite
|
Metabolic Disease
|
|
N-Acetyl-D-glucosamine- 13C3, 15N is the 13C and 15N labeled N-Acetyl-D-glucosamine. N-Acetyl-D-Glucosamine (N-Acetyl-2-amino-2-deoxy-D-glucose) is a monosaccharide derivative of gluc[1][2].
|
-
- HY-A0132S10
-
|
N-Acetyl-2-amino-2-deoxy-D-glucose-13C2,15N
|
Endogenous Metabolite
|
Metabolic Disease
|
|
N-Acetyl-D-glucosamine- 13C2, 15N is the 13C and 15N labeled N-Acetyl-D-glucosamine. N-Acetyl-D-Glucosamine (N-Acetyl-2-amino-2-deoxy-D-glucose) is a monosaccharide derivative of gluc[1][2].
|
-
- HY-A0132S11
-
|
N-Acetyl-2-amino-2-deoxy-D-glucose-13C,15N-1
|
Endogenous Metabolite
|
Metabolic Disease
|
|
N-Acetyl-D-glucosamine- 13C, 15N-1 is the 13C and 15N labeled N-Acetyl-D-glucosamine. N-Acetyl-D-Glucosamine (N-Acetyl-2-amino-2-deoxy-D-glucose) is a monosaccharide derivative of gluc[1][2].
|
-
- HY-B0400S15
-
|
Sorbitol-18O-1; D-Glucitol-18O-1
|
Endogenous Metabolite
|
Others
|
|
D-Sorbitol- 18O-1 is the 18O labeled D-Sorbitol. D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and dietary
|
-
- HY-B1659S1
-
-
- HY-B1659S2
-
-
- HY-W145584S
-
-
- HY-N0378S1
-
-
- HY-100582S
-
|
Adonitol-1-13C; Adonite-1-13C
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Others
|
|
Ribitol-1- 13C is the 13C labeled Ribitol. Ribitol is a crystalline pentose alcohol formed by the reduction of ribose. Enhancing the flux of D-glucose to the pentose phosphate pathway in Saccharomyces cerevisiae for the production of D-ribose and ribitol .
|
-
- HY-100582S1
-
|
Adonitol-2-13C; Adonite-2-13C
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Others
|
Ribitol-2- 13C is the 13C labeled Ribitol. Ribitol is a crystalline pentose alcohol formed by the reduction of ribose. Enhancing the flux of D-glucose to the pentose phosphate pathway in Saccharomyces cerevisiae for the production of D-ribose and ribitol
|
-
- HY-100582S2
-
|
Adonitol-3-13C; Adonite-3-13C
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Others
|
Ribitol-3- 13C is the 13C labeled Ribitol. Ribitol is a crystalline pentose alcohol formed by the reduction of ribose. Enhancing the flux of D-glucose to the pentose phosphate pathway in Saccharomyces cerevisiae for the production of D-ribose and ribitol
|
-
- HY-100582S3
-
|
Adonitol-5-13C; Adonite-5-13C
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Others
|
Ribitol-5- 13C is the 13C labeled Ribitol. Ribitol is a crystalline pentose alcohol formed by the reduction of ribose. Enhancing the flux of D-glucose to the pentose phosphate pathway in Saccharomyces cerevisiae for the production of D-ribose and ribitol
|
-
- HY-N0378S3
-
-
- HY-B0166S2
-
-
- HY-B0166S3
-
-
- HY-B0166S4
-
-
- HY-B0166S5
-
-
- HY-42682S1
-
|
D-Galactosamine-13C (hydrochloride)
|
Isotope-Labeled Compounds
|
Inflammation/Immunology
|
|
D(+)-Galactosamine- 13C (hydrochloride) is the 13C labeled D(+)-Galactosamine hydrochloride. D(+)-Galactosamine (D-Galactosamine) hydrochloride, which is an established experimental toxin, primarily causes liver injury by the generation of free radicals and
|
-
- HY-N0210S
-
-
- HY-N0210S1
-
-
- HY-N0210S2
-
-
- HY-N0210S3
-
-
- HY-N0210S4
-
-
- HY-N0733S
-
-
- HY-13966S4
-
|
2-DG-13C-1; 2-Deoxy-D-arabino-hexose-13C-1; D-Arabino-2-deoxyhexose-13C-1
|
Isotope-Labeled Compounds
Apoptosis
Hexokinase
HSV
|
Cancer
|
|
2-Deoxy-D-glucose- 13C-1 is the 13C labeled 2-Deoxy-D-glucose. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase[1][2].
|
-
- HY-13966S2
-
|
2-DG-13C; 2-Deoxy-D-arabino-hexose-13C; D-Arabino-2-deoxyhexose-13C
|
Isotope-Labeled Compounds
Apoptosis
Hexokinase
HSV
|
Cancer
|
|
2-Deoxy-D-glucose- 13C is the 13C labeled 2-Deoxy-D-glucose. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase[1][2].
|
-
- HY-N0733S1
-
-
- HY-N0733S2
-
-
- HY-N0733S3
-
-
- HY-U00462S
-
|
|
Isotope-Labeled Compounds
|
Metabolic Disease
|
|
D-Mannoheptulose- 13C is the 13C labeled D-Mannoheptulose. D-Mannoheptulose is a major non-structural carbohydrate in avocado. D-mannoheptulose is a specific inhibitor of D-glucose phosphorylation. D-Mannoheptulose can block insulin release and utilization
|
-
- HY-128850S1
-
|
N-Acetylmannosamine-13C; ManNAc-13C
|
Bacterial
|
Neurological Disease
|
|
N-Acetyl-D-mannosamine- 13C is the 13C labeled N-Acetyl-D-mannosamine. N-Acetyl-D-mannosamine (ManNAc) is an essential precursor of N-acetylneuraminic acid (NeuAc), the specific monomer of bacterial capsular polysialic acid (PA)[1][2]
|
-
- HY-128850S2
-
|
N-Acetylmannosamine-13C-1; ManNAc-13C-1
|
Isotope-Labeled Compounds
Bacterial
|
Neurological Disease
|
|
N-Acetyl-D-mannosamine- 13C-1 is the 13C labeled N-Acetyl-D-mannosamine. N-Acetyl-D-mannosamine (ManNAc) is an essential precursor of N-acetylneuraminic acid (NeuAc), the specific monomer of bacterial capsular polysialic acid (PA)[1][2]
|
-
- HY-I0400S
-
-
- HY-I0400S1
-
-
- HY-I0400S2
-
-
- HY-I0400S3
-
-
- HY-N7032S
-
-
- HY-B0228S4
-
-
- HY-B0228S2
-
-
- HY-B0228S3
-
-
- HY-B0228S5
-
-
- HY-B0158S1
-
-
- HY-N1150S4
-
-
- HY-N1150S5
-
-
- HY-N1150S2
-
-
- HY-N1150S3
-
-
- HY-B0158S2
-
-
- HY-N0092S1
-
-
- HY-N1420AS
-
|
L-Rhamnose-13C monohydrate
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Cancer
|
|
Rhamnose- 13C (monohydrate) is the 13C labeled Rhamnose monohydrate. Rhamnose monohydrate (L-Rhamnose monohydrate) is a monosaccharide found in plants and bacteria. Rhamnose monohydrate-conjugated immunogens is used in immunotherapies. Rhamnose monohydrate c
|
-
- HY-N1420AS2
-
|
L-Rhamnose-13C-2 monohydrate
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Cancer
|
|
Rhamnose- 13C-2 (monohydrate) is the 13C labeled Rhamnose monohydrate. Rhamnose monohydrate (L-Rhamnose monohydrate) is a monosaccharide found in plants and bacteria. Rhamnose monohydrate-conjugated immunogens is used in immunotherapies. Rhamnose monohydrate
|
-
- HY-N0537S2
-
-
- HY-N0537S3
-
-
- HY-N0537S4
-
-
- HY-N0537S5
-
-
- HY-N0537S6
-
-
- HY-N0733S4
-
-
- HY-N0733S5
-
-
- HY-128850S5
-
|
N-Acetylmannosamine-15N; ManNAc-15N
|
Isotope-Labeled Compounds
Bacterial
|
Neurological Disease
|
|
N-Acetyl-D-mannosamine- 15N is the 15N labeled N-Acetyl-D-mannosamine. N-Acetyl-D-mannosamine (ManNAc) is an essential precursor of N-acetylneuraminic acid (NeuAc), the specific monomer of bacterial capsular polysialic acid (PA)[1][2]
|
-
- HY-N0537S
-
-
- HY-112251S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
D-Lin-MC3-DMA- 13C3 is the 13C labeled D-Lin-MC3-DMA. D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle[1][2].
|
-
- HY-108226S1
-
-
- HY-108872S
-
-
- HY-W010382S
-
|
2-Oxosuccinic acid-13C4
|
Endogenous Metabolite
Isotope-Labeled Compounds
|
Metabolic Disease
|
|
Oxaloacetic acid- 13C4 is the 13C-labeled Oxaloacetic acid. Oxaloacetic acid (2-Oxosuccinic acid) is a metabolic intermediate involved in several ways, such as citric acid cycle, gluconeogenesis, the urea cycle, the glyoxylate cycle, amino acid synthesis, and fatty acid synthesis[1][2][3].
|
-
- HY-Y1269S
-
-
- HY-B0228S10
-
|
(R)-(-)-3-Hydroxybutanoic acid-13C2 sodium; (R)-3-Hydroxybutyric acid-13C2 sodium
|
Endogenous Metabolite
|
Metabolic Disease
|
|
(R)-3-Hydroxybutanoic acid- 13C2 (sodium) is the 13C labeled (R)-3-Hydroxybutanoic acid (sodium) (HY-W015851). (R)-3-Hydroxybutanoic acid (sodium) is a metabolite converted from acetoacetic acid catalyzed by 3-hydroxybutyrate dehydrogenase. (R)-3-Hydroxybutanoic acid sodium can function as a nutrition source, and as a precursor for vitamins, antibiotics and pheromones[1][2][3].
|
-
- HY-W010452S1
-
-
- HY-W010452S2
-
-
- HY-B0495S4
-
|
LTG-13C3; BW430C-13C3
|
Sodium Channel
Autophagy
|
Neurological Disease
|
|
Lamotrigine- 13C3 is the 13C-labeled Lamotrigine. Lamotrigine (BW430C) is a potent and orally active anticonvulsant or antiepileptic agent. Lamotrigine selectively blocks voltage-gated Na+ channels, stabilizing presynaptic neuronal membranes and inhibiting glutamate release. Lamotrigine can be used for the research of epilepsy, focal seizure, et al[1][2].
|
-
- HY-15398S4
-
-
- HY-B0853S
-
|
|
Fungal
|
Others
|
|
(Rac)-Paclobutrazol- 15N3 is the 15N-labeled Rac-Paclobutrazol[1].
|
-
- HY-N6625S
-
|
|
Fungal
|
Inflammation/Immunology
|
|
Chlorothalonil- 13C2 is the 13C-labeled Chlorothalonil. Chlorothalonil is a broad spectrum fungicide and is effective in protecting plants against fungal diseases caused mainly by Phytophthora infestans and Alternaria solani. Chlorothalonil is used for controlling of fungal foliar diseases of vegetables and crops[1][2].
|
-
- HY-125296S
-
-
- HY-B0822S1
-
|
|
GABA Receptor
Cytochrome P450
|
Inflammation/Immunology
|
|
Fipronil- 13C6 is the 13C-labeled Fipronil. Fipronil is an insecticide that acts as a selective antagonist of insect GABA receptors (IC50s = 30 nM and 1,600 nM for cockroach and rat receptors, respectively). Fipronil also inhibits desensitizing and non-desensitizing glutamate-induced chloride currents in cockroach neurons (IC50s = 800 nM and 10 nM, respectively). Fipronil induces activity of the cytochrome P450 (CYP) isoforms CYP1A1/2, CYP2B1/2, and CYP3A1/2 in isolated rat liver microsomes.
|
-
- HY-B2225AS
-
-
- HY-W012835S2
-
|
4-Methoxytoluene-13C
|
Isotope-Labeled Compounds
|
Others
|
|
4-Methylanisole- 13C is the 13C-labeled 4-Methylanisole. 4-Methylanisole (4-Methoxytoluene) is food flavoring agent and can be naturally found in Ylang Ylang fragrance oil[1].
|
-
- HY-152039S1
-
-
- HY-N0172S
-
|
3,4-Dihydroxycinnamic acid-13C3
|
Bacterial
Fungal
|
Infection
|
|
Caffeic acid- 13C3 is an 13C labeled caffeic acid. Caffeic acid is a phytonutrient belonging to the flavonoids. Caffeic acid and its derivatives, are potential antimicrobial agents, chronic infection induced by microbes such as bacteria, fungi, and viruses[1].
|
-
- HY-N0210S16
-
-
- HY-101541S1
-
|
Methyl docosahexaenoate-13C22; all cis-DHA methyl ester-13C22
|
Isotope-Labeled Compounds
|
Others
|
|
Docosahexaenoic acid- 13C22 methyl ester is the 13C22 labeled Docosahexaenoic acid methyl ester (HY-101541)[1].
|
-
- HY-113295S
-
-
- HY-136648S
-
|
dATP-13C10,15N5 (tetraammonia)
|
Isotope-Labeled Compounds
|
Others
|
|
2'-Deoxyadenosine-5'-triphosphate- 13C10, 15N5 (tetraammonia) is the 13C10 ans 15N5 labeled 2'-Deoxyadenosine-5'-triphosphate (HY-136648)[1].
|
-
- HY-16637S4
-
-
- HY-18341S3
-
-
- HY-N0092S2
-
-
- HY-W013378S3
-
-
- HY-W013378S4
-
-
- HY-W013378S5
-
-
- HY-W357090S
-
-
- HY-Y1069S3
-
|
(S)-Hydroxybutanedioic acid-13C4; (S)-E 296-13C4; L-Malic acid-13C4
|
Isotope-Labeled Compounds
|
Others
|
|
(S)-Malic acid- 13C4 is the 13C labeled S-Malic acid (HY-Y1069)[1].
|
-
- HY-A0070AS2
-
|
Triiodothyronine-13C6-1; 3,3',5-Triiodo-L-thyronine-13C6-1; T3-13C6-1
|
Thyroid Hormone Receptor
|
Endocrinology
Cancer
|
|
Liothyronine-13C6-1 is a 13C-labeled Liothyronine. Liothyronine is a potent thyroid hormone receptors TRα and TRβ agonist with Kis of 2.33 nM for hTRα and hTRβ, respectively .
|
-
- HY-B0445S
-
|
β-DPN-13C5 ammonium; β-NAD-13C5 ammonium; β-Nicotinamide Adenine Dinucleotide-13C5 ammonium
|
Isotope-Labeled Compounds
|
Metabolic Disease
|
|
NAD+-13C5 (ammonium) is the 13C labled NAD+ (HY-B0445), with an ammonium .
|
-
- HY-A0130S
-
-
- HY-N0667S7
-
|
(-)-Asparagine-13C4,15N2; Asn-13C4,15N2; Asparamide-13C4,15N2
|
Isotope-Labeled Compounds
|
Others
|
|
L-Asparagine-13C4,15N2 ((-)-Asparagine-13C4,15N2) is the 13C and 15N-labeled L-Aspartic acid. L-Aspartic acid is an amino acid, shown to be a suitable pro-agent for colon-specific drug delivery .
|
-
- HY-N0610AS2
-
|
3-Phenylacrylic acid-13C3; β-Phenylacrylic acid-13C3
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Cancer
|
|
Cinnamic acid- 13C3 (3-Phenylacrylic acid- 13C3) is the 13C labeled Cinnamic acid (HY-N0610A). Cinnamic acid has potential use in cancer intervention, with IC50s of 1-4.5 mM in glioblastoma, melanoma, prostate and lung carcinoma cells .
|
-
- HY-10163S2
-
|
BIBR 953-13C6; BIBR 953ZW-13C6
|
Thrombin
|
Cardiovascular Disease
|
|
Dabigatran- 13C6 is the 13C labeled Dabigatran[1]. Dabigatran (BIBR 953), an oral anticoagulant, is a reversible, potent, competitive direct thrombin inhibitor (Ki=4.5 nM). Dabigatran (BIBR 953) also inhibits thrombin-induced platelet aggregation (IC50=10 nM)[2][3].
|
-
- HY-101981S
-
|
5'-?Uridylic acid-15N2
|
Endogenous Metabolite
|
Others
|
|
Uridine 5'-monophosphate-15N2 is the 15N labeled Uridine 5'-monophosphate[1]. Uridine 5'-monophosphate (5'- Uridylic acid), a monophosphate form of UTP, can be acquired either from a de novo pathway or degradation products of nucleotides and nucleic acids in vivo and is a major nucleotide analogue in mammalian milk[2].
|
-
- HY-103395S1
-
|
|
Endogenous Metabolite
|
Cancer
|
|
Methylmalonic acid- 13C4 is the 13C labeled Methylmalonic acid[1]. Methylmalonic acid (Methylmalonate) is an indicator of Vitamin B-12 deficiency in cancer[2].
|
-
- HY-108872S1
-
-
- HY-109591S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
Oleoyl coenzyme A- 13C18 (lithium) is the 13C labeled Oleoyl Coenzyme A lithium[1]. Oleoyl coenzyme A (Oleoyl-CoA) is a thioester of oleic acid and coenzyme A. Oleoyl coenzyme A has a role as an Escherichia coli metabolite and a mouse metabolite[2][3].
|
-
- HY-113008S1
-
|
|
Endogenous Metabolite
|
Cancer
|
|
Urocanic acid- 13C3 is the 13C labeled Urocanic acid[1]. Urocanic acid, produced in the upper layers of mammalian skin, is a major absorber of ultraviolet radiation (UVR)[2].
|
-
- HY-113038AS
-
|
2-Hydroxyglutarate-13C5 disodium; 2-Hydroxyglutaric acid-13C5 sodium; 2-Hydroxypentanedioic acid-13C5 disodium
|
Histone Demethylase
Endogenous Metabolite
|
Cancer
|
|
α-Hydroxyglutaric acid- 13C5 (sodium) is the 13C labeled α-Hydroxyglutaric acid sodium[1]. α-Hydroxyglutaric acid (2-Hydroxyglutarate) sodium is an α-hydroxy acid form of glutaric acid. α-Hydroxyglutaric acid sodium is a competitive inhibitor of multiple α-ketoglutarate-dependent dioxygenases, including histone demethylases and the TET family of 5-methlycytosine (5mC) hydroxylases[2].
|
-
- HY-113225S1
-
-
- HY-113248S1
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
3-Nitro-L-tyrosine- 13C6 is the 13C labeled 3-Nitro-L-tyrosine[1]. 3-Nitro-L-tyrosine is a biomarker of nitrogen free radical species modified proteins in systemic autoimmunogenic conditions[2].
|
-
- HY-12008S1
-
|
CP-358774-13C6 hydrochloride; NSC 718781-13C6 hydrochloride; OSI-774-13C6 hydrochloride
|
EGFR
Autophagy
|
Cancer
|
|
Erlotinib- 13C6 (hydrochloride) is the 13C labeled Erlotinib Hydrochloride[1]. Erlotinib Hydrochloride (CP-358774 Hydrochloride) inhibits purified EGFR kinase with an IC50 of 2 nM[2]. Erlotinib-13C6 (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-122062S
-
-
- HY-128738S
-
|
TMP-13C10,15N2
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Thymidine-5'-monophosphate- 13C10, 15N2 (disodium) is the 13C and 15N labeled Thymidine-5'-monophosphate disodium salt[1]. Thymidine-5'-monophosphate disodium salt is an endogenous metabolite.
|
-
- HY-128793S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
trans-Stilbene- 13C2 is the 13C labeled trans-Stilbene[1]. trans-Stilbene ((E)-Stilbene) is used in the manufacturing of dye lasers, optical brighteners, non-steroidal synthetic estrogens[2].
|
-
- HY-129974S
-
|
3,3'-T2-13C6
|
COX
Endogenous Metabolite
|
Metabolic Disease
|
|
3,3'-Diiodo-L-thyronine- 13C6 is the 13C labeled 3,3'-Diiodo-L-thyronine[1]. 3,3'-Diiodo-L-thyronine (3,3'-T2) is an endogenous metabolite of thyroid hormone. 3,3'-Diiodo-L-thyronine significantly enhances COX activity[2][3].
|
-
- HY-134423S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
Stearoyl coenzyme A- 13C18 (lithium) is the 13C labeled Stearoyl coenzyme A lithium[1]. Stearoyl coenzyme A (Stearoyl-CoA) lithium is an active compound that can be used as a substrate for the determination of stearoyl-Coenzyme desaturase in microsomes[2].
|
-
- HY-13613S
-
|
GG 745-13C6; GI 198745-13C6
|
Apoptosis
5 alpha Reductase
|
Cancer
|
|
Dutasteride- 13C6 is the 13C labeled Dutasteride[1]. Dutasteride (GG745) is a potent inhibitor of both 5α-reductase isozymes. Dutasteride may possess off-target effects on the androgen receptor (AR) due to its structural similarity to DHT[2].
|
-
- HY-13623CS
-
-
- HY-13690S1
-
|
2,4′-DDD-13C6; o,p'-DDD-13C6
|
Apoptosis
|
Cancer
|
|
Mitotane- 13C6 is the 13C labeled Mitotane[1]. Mitotane (2,4′-DDD), an isomer of DDD and derivative of dichlorodiphenyltrichloroethane (DDT), is an antineoplastic agent, can be used to research adrenocortical carcinoma. Mitotane exert its adrenocorticolytic effect at least in part through lipotoxicity induced by intracellular free cholesterol (FC) accumulation. Mitotane can have direct pituitary effects on corticotroph cells. Mitotane can induce CYP3A4 gene expression via steroid and xenobiotic receptor (SXR) activation, and has agent-agent interactions[2][3][4][5].
|
-
- HY-139427S
-
-
- HY-143843S
-
-
- HY-14608S10
-
|
|
Apoptosis
iGluR
Ferroptosis
Endogenous Metabolite
|
Neurological Disease
|
|
L-Glutamic acid- 13C2 is the 13C labeled L-Glutamic acid[1]. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals[2].
|
-
- HY-14781S2
-
-
- HY-15027S2
-
|
Mesalamine-13C6; 5-ASA-13C6; Mesalazine-13C6
|
PPAR
PAK
NF-κB
Endogenous Metabolite
|
Inflammation/Immunology
|
|
5-Aminosalicylic acid- 13C6 is the 13C labeled 5-Aminosalicylic Acid[1]. 5-Aminosalicylic acid (Mesalamine) acts as a specific PPARγ agonist and also inhibits p21-activated kinase 1 (PAK1) and NF-κB[2][3][4].
|
-
- HY-150525S
-
-
- HY-150532S
-
-
- HY-150631S
-
-
- HY-150635S
-
-
- HY-150642S
-
-
- HY-150656S
-
-
- HY-150658S
-
-
- HY-150660S
-
|
25-Hydroxy Vitamin D2-13C5
|
Isotope-Labeled Compounds
|
Others
|
|
25-Hydroxyvitamin D2-(20,21,22,26,27- 13C5) solution is the 13C labeled 25-Hydroxyvitamin D2[1].
|
-
- HY-150661S
-
-
- HY-150663S
-
|
1,25-Dihydroxyvitamin D3-13C5
|
Isotope-Labeled Compounds
|
Others
|
|
1α,25-Dihydroxyvitamin D3-(23,24,25,26,27- 13C5) solution is the 13C labeled 1α,25-Dihydroxyvitamin D3[1].
|
-
- HY-150678S
-
-
- HY-150679S
-
-
- HY-150703S
-
-
- HY-150706S
-
-
- HY-150707S
-
-
- HY-150708S
-
-
- HY-150709S
-
-
- HY-150710S
-
-
- HY-150711S
-
-
- HY-150712S
-
|
UTP-13C9,15N2 dilithium; Uridine 5'-triphosphate-13C9,15N2 dilithium
|
Isotope-Labeled Compounds
|
Others
|
|
Uridine triphosphate- 13C9, 15N5 dilithium is the 13C and 15N labeled Uridine triphosphate dilithium .
|
-
- HY-150792S
-
-
- HY-150796S
-
-
- HY-150798S
-
-
- HY-150843S
-
-
- HY-150915S
-
-
- HY-150918S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
3-(3-Methyl-1H-Prazol-5-yl)Propanoic Acid (MPP) Methyl,pyrazol yl- 13C5 is the 13C labeled 3-(3-Methyl-1H-Prazol-5-yl)Propanoic Acid (MPP) Methyl,pyrazol yl[1].
|
-
- HY-150930S
-
-
- HY-150962S
-
-
- HY-150980S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
1,2-O-Isopropylidene-β-L-idofuranuronic-6- 13C acid γ-lactone is the 13C labeled 1,2-O-Isopropylidene-β-L-idofuranuronic acid γ-lactone[1].
|
-
- HY-150981S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
1,2-O-Isopropylidene-a-D-glucofuranuronic-6- 13C acid, γ-lactone is the 13C labeled 1,2-O-Isopropylidene-β-L-idofuranuronic acid, γ-lactone[1].
|
-
- HY-151097S
-
-
- HY-15550S1
-
|
|
Drug Metabolite
|
Inflammation/Immunology
|
|
4'-Hydroxy diclofenac- 13C6 is the 13C labeled 4'-Hydroxy diclofenac[1]. 4'-Hydroxy diclofenac is an orally active metabolite of Diclofenac (HY-15036) by cytochrome P450 2C9 (CYP2C9). 4'-Hydroxy diclofenac has anti-inflammatory and analgesic properties[2][3].
|
-
- HY-16561S2
-
-
- HY-17416AS
-
|
|
Adrenergic Receptor
|
Neurological Disease
|
|
Guanfacine- 13C, 15N3 is the 13C and 15N labeled Guanfacine[1]. Guanfacine is an orally active noradrenergic α2A agonist and has high selective for the α2A receptor subtype. Guanfacine has effects in producing hypotension and sedation. Guanfacine can be used for the research of a variety of prefrontal cortex (PFC) cognitive disorders, including tourette's syndrome and attention deficit hyperactivity disorder (ADHD)[2][3][4].
|
-
- HY-18341S2
-
|
|
Thyroid Hormone Receptor
Endogenous Metabolite
|
Endocrinology
|
|
L-Thyroxine- 13C6 is the 13C labeled L-Thyroxine[1]. L-Thyroxine (Levothyroxine;T4) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4)[2].
|
-
- HY-18569S4
-
|
Indole-3-acetic acid-13C6; 3-IAA-13C6
|
Endogenous Metabolite
Molecular Glues
|
Others
|
|
3-Indoleacetic acid- 13C6 is the 13C labeled 3-Indoleacetic acid[1]. 3-Indoleacetic acid (Indole-3-acetic acid) is the most common natural plant growth hormone of the auxin class. It can be added to cell culture medium to induce plant cell elongation and division .
|
-
- HY-19528S2
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
SAH- 13C10 is the 13C labeled SAH[1]. SAH (S-Adenosylhomocysteine) is an amino acid derivative and a modulartor in several metabolic pathways. It is an intermediate in the synthesis of cysteine and adenosine[2]. SAH is an inhibitor for METTL3-METTL14 heterodimer complex (METTL3-14) with an IC50 of 0.9 μM[3].
|
-
- HY-19821S1
-
|
Fmoc-L-isoleucine-13C6,15N
|
Isotope-Labeled Compounds
|
Others
|
|
Fmoc-Ile-OH- 13C6, 15N is the 13C and 15N labeled Fmoc-Ile-OH[1]. Fmoc-Ile-OH is an isoleucine derivative[2].
|
-
- HY-21268S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
Methyl linolenate- 13C18 is the 13C labeled Methyl linolenate[1]. Methyl linolenate is a polyunsaturated fattly acid (PUFA). It is used in studies on the mechanisms and prevention of oxidation/peroxidation of unsaturated fatty acids[2][3]. The IC50 is 60 uM[4].
|
-
- HY-22306S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
β-D-Glucose pentaacetate- 13C6 is the 13C labeled β-D-Glucose pentaacetate[1]. β-D-Glucose Pentaacetate (Penta-O-acetyl-β-D-glucopyranose) is used in biochemical reaction.
|
-
- HY-41494S1
-
|
|
Endogenous Metabolite
|
Others
|
|
o-Toluic acid-13C is the 13C labeled o-Toluic acid[1]. o-Toluic acid (2-Methylbenzoic acid) is a benzoic acid substituted by a methyl group at position 2. O-Toluic acid plays a role as a xenobiotic metabolite.
|
-
- HY-59243S
-
-
- HY-66005S4
-
|
Paracetamol-13C2,15N; 4-Acetamidophenol-13C2,15N; 4'-Hydroxyacetanilide-13C2,15N
|
COX
Bacterial
Histone Acetyltransferase
Parasite
Endogenous Metabolite
|
Inflammation/Immunology
|
|
Acetaminophen- 13C2, 15N is the 13C and 15N labeled Acetaminophen[1]. Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM;is a widely used antipyretic and analgesic agent[2][3][4]. Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor[5].
|
-
- HY-79131S5
-
-
- HY-79369S1
-
|
|
ADC Linker
|
Cancer
|
|
Succinic anhydride- 13C2 is the 13C labeled Succinic anhydride[1]. Succinic anhydride is a cyclic anhydride and a nonclaevable ADC linker extracted from patent WO2009064913A1. Succinic anhydride can react with compound 4 of the patent to link the proagent to an amine or hydroxy 1 group of a targeting polypeptide[2].
|
-
- HY-90006S1
-
|
5-FU-13C,15N2
|
Apoptosis
Nucleoside Antimetabolite/Analog
HIV
Endogenous Metabolite
|
Cancer
|
|
5-Fluorouracil- 13C, 15N2 is the 13C and 15N labeled 5-Fluorouracil[1]. 5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer[2][3]. 5-Fluorouracil also inhibits HIV[4].
|
-
- HY-90006S3
-
|
5-FU-13C4,15N2
|
Apoptosis
Nucleoside Antimetabolite/Analog
HIV
Endogenous Metabolite
|
Cancer
|
|
5-Fluorouracil- 13C4, 15N2 is the 13C and 15N labeled 5-Fluorouracil[1]. 5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer[2][3]. 5-Fluorouracil also inhibits HIV[4].
|
-
- HY-A0061S
-
|
Trifluorothymidine-13C,15N2; 5-Trifluorothymidine-13C,15N2; TFT-13C,15N2
|
Thymidylate Synthase
Nucleoside Antimetabolite/Analog
HSV
Orthopoxvirus
|
Cancer
|
|
Trifluridine- 13C, 15N2 is the 13C and 15N labeled Trifluridine[1]. Trifluridine (Trifluorothymidine;5-Trifluorothymidine;TFT) is an irreversible thymidylate synthase inhibitor, and thereby suppresses DNA synthesis. Trifluridine is an antiviral agent for herpes simplex virus (HSV) infection. Trifluorothymidine also has anti-orthopoxvirus activity[2].
|
-
- HY-A0070AS1
-
|
Triiodothyronine-13C9,15N; 3,3',5-Triiodo-L-thyronine-13C9,15N; T3-13C9,15N
|
Thyroid Hormone Receptor
Endogenous Metabolite
|
Cancer
|
|
Liothyronine- 13C9, 15N is the 13C and 15N labeled Liothyronine[1]. Liothyronine is an active form of thyroid hormone. Liothyronine is a potent thyroid hormone receptors TRα and TRβ agonist with Kis of 2.33 nM for hTRα and hTRβ, respectively[2][3][4].
|
-
- HY-B0003AS
-
-
- HY-B0003S
-
|
LY 188011-13C,15N2 hydrochloride
|
Apoptosis
Nucleoside Antimetabolite/Analog
DNA/RNA Synthesis
Autophagy
|
Cancer
|
|
Gemcitabine- 13C, 15N2 (hydrochloride) is the 13C and 15N labeled Gemcitabine hydrochloride[1]. Gemcitabine Hydrochloride (LY 188011 Hydrochloride) is a pyrimidine nucleoside analog antimetabolite and an antineoplastic agent. Gemcitabine Hydrochloride inhibits DNA synthesis and repair, resulting in autophagyand apoptosis[2][3].
|
-
- HY-B0143S4
-
|
|
Autophagy
Endogenous Metabolite
|
Cancer
|
|
Niacin- 15N, 13C3 is the 13C and 15N labeled Niacin[1]. Niacin (Vitamin B3) is an orally active water-soluble B3 vitamin that is an essential nutrient for humans. Niacin (Vitamin B3) plays a key role in energy metabolism, cell signaling cascades regulating gene expression and apoptosis. Niacin (Vitamin B3) is also used in the study of cardiovascular diseases[2][3].
|
-
- HY-B0152S1
-
|
Adenine-8-C13; 9H-Purin-6-amine-8-13C
|
DNA/RNA Synthesis
Endogenous Metabolite
|
Cancer
|
|
Adenine- 13C is the 13C labeled Adenine[1]. Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis[2][3][4].
|
-
- HY-B0158S5
-
|
Cytosine β-D-riboside-13C9,15N3; Cytosine-1-β-D-ribofuranoside-13C9,15N3
|
Nucleoside Antimetabolite/Analog
Endogenous Metabolite
|
Neurological Disease
|
|
Cytidine- 13C9, 15N3 is the 13C and 15N labeled Cytidine[1]. Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catecholamine synthesis, and mitochondrial function[2][3][4].
|
-
- HY-B0158S6
-
|
Cytosine β-D-riboside-15N3; Cytosine-1-β-D-ribofuranoside-15N3
|
Nucleoside Antimetabolite/Analog
Endogenous Metabolite
|
Neurological Disease
|
|
Cytidine- 15N3 is the 15N labeled Cytidine[1]. Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catecholamine synthesis, and mitochondrial function[2][3][4].
|
-
- HY-B0211S
-
|
PK 26124-13C,15N2
|
GABA Receptor
Sodium Channel
|
Neurological Disease
|
|
Riluzole- 13C, 15N2 is the 13C and 15N labeled Riluzole[1]. Riluzole is an anticonvulsant agent and belongs to the family of use-dependent Na+ channel blocker which can also inhibit GABA uptake with an IC50 of 43 μM[2][3].
|
-
- HY-B0224S
-
-
- HY-B0228S1
-
|
Adenine riboside-13C5; D-Adenosine-13C5
|
Apoptosis
Nucleoside Antimetabolite/Analog
Autophagy
Endogenous Metabolite
|
Cancer
|
|
Adenosine- 13C5 is the 13C labeled Adenosine[1]. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation[2][3].
|
-
- HY-B0252S2
-
|
HCTZ-13C6
|
TGF-beta/Smad
Potassium Channel
|
Metabolic Disease
|
|
Hydrochlorothiazide- 13C6 is the 13C labeled Hydrochlorothiazide[1]. Hydrochlorothiazide (HCTZ), an orally active diuretic agent of the thiazide class, inhibits transforming TGF-β/Smad signaling pathway. Hydrochlorothiazide has direct vascular relaxant effects via opening of the calcium-activated potassium (KCA) channel. Hydrochlorothiazide improves cardiac function, reduces fibrosis and has antihypertensive effect[2][3][4].
|
-
- HY-B0285AS
-
|
MK-870-15N3 hydrochloride
|
Apoptosis
TRP Channel
Sodium Channel
|
Metabolic Disease
|
|
Amiloride- 15N3 (hydrochloride) is the 15N labeled Amiloride hydrochloride[1]. Amiloride hydrochloride (MK-870 hydrochloride) is an inhibitor of both epithelial sodium channel (ENaC[2]) and urokinase-type plasminogen activator receptor (uTPA[3]). Amiloride hydrochloride is a blocker of polycystin-2 (PC2;TRPP2[4]) channel.
|
-
- HY-B0345AS
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
ATP- 18O4 (disodium salt) is the 18O labeled ATP disodium salt[1]. ATP disodium salt (Adenosine 5'-triphosphate disodium salt) is a central component of energy storage and metabolism in vivo, provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP disodium salt is an important endogenous signaling molecule in immunity and inflammation[2][3].
|
-
- HY-B0347S1
-
|
|
Apoptosis
Caspase
Calcium Channel
Reactive Oxygen Species
|
Cardiovascular Disease
|
|
Lacidipine- 13C8 is the deuterium labeled Lacidipine[1]. Lacidipine is an orally active and highly selective L-type calcium channel blocker that acts on smooth muscle calcium channels, primarily dilates peripheral arteries, reduces peripheral resistance, and has long-lasting anti-hypertensive activity. Lacidipine protects HKCs from apoptosis induced by ATP depletion and recovery by modulating the caspase-3 pathway. Lacidipine can be used in studies of hypertension, atherosclerosis and acute kidney injury (AKI)[2][3].
|
-
- HY-B0400S16
-
|
Sorbitol-13C6; D-Glucitol-13C6
|
Bacterial
Endogenous Metabolite
|
Others
|
|
D-Sorbitol- 13C6 is the 13C labeled D-Sorbitol[1]. D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and dietary supplement[2].
|
-
- HY-B0445S1
-
|
β-DPN-13C5; β-NAD-13C5; β-Nicotinamide Adenine Dinucleotide-13C5
|
Endogenous Metabolite
|
Metabolic Disease
|
|
NAD+- 13C5-1 is the 13C labeled NAD+[1]. NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage.
|
-
- HY-B0448S1
-
|
|
Sodium Channel
Virus Protease
|
Neurological Disease
|
|
Phenytoin- 15N2, 13C is the 13C and 15N labeled Phenytoin[1]. Phenytoin (5,5-Diphenylhydantoin) is a potent Voltage-gated Na+ channels (VGSCs) blocker. Phenytoin has antiepileptic activity and reduces breast tumour growth and metastasis in mice[2][3].
|
-
- HY-B0476S1
-
|
|
COX
|
Inflammation/Immunology
|
|
Phenacetin- 13C is the 13C labeled Phenacetin[1]. Phenacetin (Acetophenetidin) is a non-opioid analgesic/antipyretic agent. Phenacetin is a selective COX-3 inhibitor. Phenacetin is used as probe of cytochrome P450 enzymes CYP1A2 in human liver microsomes and in rats[2][3][4].
|
-
- HY-B0495S3
-
|
|
Autophagy
Sodium Channel
|
Neurological Disease
|
|
Lamotrigine-13C2,15N is the 13C and 15N labeled Lamotrigine[1]. Lamotrigine (BW430C) is a potent and orally active anticonvulsant or antiepileptic agent. Lamotrigine selectively blocks voltage-gated Na+ channels, stabilizing presynaptic neuronal membranes and inhibiting glutamate release. Lamotrigine can be used for the research of epilepsy, focal seizure, et al[2][3].
|
-
- HY-B0497BS
-
|
BAY2353-13C6 monohydrate
|
STAT
Parasite
Antibiotic
|
Cancer
|
|
Niclosamide- 13C6 (monohydrate) is the 13C labeled Niclosamide monohydrate[1]. Niclosamide (BAY2353) monohydrate is an orally active antihelminthic agent used in parasitic infection research[2]. Niclosamide monohydrate is a STAT3 inhibitor with an IC50 of 0.25 μM in HeLa cells[5]. Niclosamide monohydrate has biological activities against cancer, and inhibits DNA replication in Vero E6 cells[3][4][6].
|
-
- HY-B0617S1
-
|
S-Adenosyl methionine-13C; Ademetionine-13C; AdoMet--13C
|
Endogenous Metabolite
|
Cancer
|
|
S-Adenosyl-L-methionine- 13C is the 13C labeled S-Adenosyl-L-methionine[1]. S-Adenosyl-L-methionine (S-Adenosyl methionine) is produced endogenously from methionine and ATP by action of the enzyme methionine adenosyltransferase and is an important orally active methyl group donor. S-Adenosyl-L-methionine is a dietary supplement with potent antidepressant effects, and has the potential for liver disease and osteoarthritis research[2][3][4].
|
-
- HY-B0892S3
-
-
- HY-B1075AS
-
|
MK-0955 (benzylamine)-13C3
|
Bacterial
Antibiotic
|
Infection
|
|
(Rac)-Fosfomycin (benzylamine)- 13C3 is the 13C labeled Fosfomycin[1]. Fosfomycin (MK-0955) is a broad-spectrum antibiotic. Fosfomycin can cross blood-brain barrier penetrating, and irreversibly inhibits an early stage in cell wall synthesis. Fosfomycin shows anti-bacteria activity for a range of bacteria, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria[2][3].
|
-
- HY-B1337S5
-
|
|
nAChR
Endogenous Metabolite
|
Cancer
|
|
Choline- 13C2 (chloride) is the 13C labeled Choline chloride[1]. Choline chloride is an essential nutrient that activates alpha7 nicotinic receptors and has analgesic and anti-inflammatory activity. Glycerophosphoinositol choline can affect diseases such as liver disease, atherosclerosis and neurological disorders[2][3].
|
-
- HY-B1409S
-
|
ISDN-13C6
|
NO Synthase
|
Cardiovascular Disease
|
|
Isosorbide dinitrate- 13C6 is the 13C labeled Isosorbide dinitrate[1]. Isosorbide dinitrate (ISDN) is an NO donor that prevents LV remodeling and degradation of cardiac function following myocardial infarction (MI)[2].
|
-
- HY-B1431S1
-
|
Butyl parahydroxybenzoate-13C6; Butyl paraben-13C6; Butyl 4-hydroxybenzoate-13C6
|
Bacterial
Endogenous Metabolite
|
Infection
|
|
Butylparaben- 13C6 is the 13C labeled Butylparaben[1]. Butylparaben is an organic compound, has proven to be a highly successful antimicrobial preservative in cosmetics, also used in medication suspensions, and as a flavoring additive in food.
|
-
- HY-B1449S
-
-
- HY-B1449S7
-
-
- HY-B1459AS
-
|
|
Bacterial
Antibiotic
|
Infection
|
|
Dicloxacillin- 13C4 is the 13C labeled Dicloxacillin[1]. Dicloxacillin is a β-lactam antibiotic of the penicillin family. Dicloxacillin against Gram-positive bacteria. Dicloxacillin is active against β-lactamase-producing organisms such as Staphylococcus aureus[2].
|
-
- HY-B1659S4
-
|
Glycerin-13C2
|
Endogenous Metabolite
|
Cancer
|
|
Glycerol- 13C2 is the 13C labeled Glycerol[1]. Glycerol is used in sample preparation and gel formation for polyacrylamide gel electrophoresis[2][3][4].
|
-
- HY-B1659S5
-
|
Glycerin-13C3
|
Endogenous Metabolite
|
Cancer
|
|
Glycerol- 13C3 is the 13C labeled Glycerol[1]. Glycerol is used in sample preparation and gel formation for polyacrylamide gel electrophoresis[2][3][4].
|
-
- HY-B1773AS
-
-
- HY-B1773AS3
-
-
- HY-B1779S5
-
|
D-(+)-Saccharose-13C6
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Sucrose-13C6 is the 13C labeled Sucrose[1]. Sucrose (D-(+)-Saccharose) is a disaccharide which is composed of two monosaccharides, glucose and fructose. Sucrose can be applied in some animal models, including metabolic disease, obesity, diet on preference, and diabetes, et al[2].
|
-
- HY-B2130S1
-
|
|
Endogenous Metabolite
Reactive Oxygen Species
|
Inflammation/Immunology
|
|
Uric acid- 15N2 is the 15N labeled Uric acid . Uric acid, scavenger of oxygen radical, is a very important antioxidant that help maintains the stability of blood pressure and antioxidant stress. Uric acid can remove reactive oxygen species (ROS) such as singlet oxygen and peroxynitrite, inhibiting lipid peroxidation .
|
-
- HY-B2176S
-
|
Adenosine 5'-triphosphate-13C10,15N5
|
Endogenous Metabolite
|
Metabolic Disease
|
|
ATP- 13C10, 15N5 is the 13C and 15N labeled ATP[1]. ATP (Adenosine 5'-triphosphate) is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation[2][3].
|
-
- HY-B2227BS2
-
|
Lactic acid-13C sodium
|
Isotope-Labeled Compounds
|
Metabolic Disease
|
|
Lactate- 13C (sodium) is the 13C labeled Lactate sodium[1]. Lactate (Lactic acid) sodium is the product of glycogenolysis and glycolysis. Lactate (Lactic acid) sodium functions in a variety of biochemical processes[2].
|
-
- HY-B2227BS3
-
|
Lactic acid-13C-1 sodium
|
Isotope-Labeled Compounds
|
Metabolic Disease
|
|
Lactate- 13C-1 (sodium) is the 13C labeled Lactate (sodium)[1]. Lactate (Lactic acid) sodium is the product of glycogenolysis and glycolysis. Lactate (Lactic acid) sodium functions in a variety of biochemical processes[2].
|
-
- HY-D0184S2
-
|
Deoxycytidine-15N3; Cytosine deoxyriboside-15N3; Deoxyribose cytidine-15N3
|
Endogenous Metabolite
|
Others
|
|
2'-Deoxycytidine- 15N3 is the 15N labeled 2'-Deoxycytidine[1]. 2'-Deoxycytidine, a deoxyribonucleoside, could inhibit biological effects of Bromodeoxyuridine (Brdu)[2].
|
-
- HY-D0185S4
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
2'-Deoxyguanosine- 13C10, 15N5 (monohydrate) is the 13C and 15N labeled 2'-Deoxyguanosine monohydrate[1]. 2'-Deoxyguanosine monohydrate is an endogenous metabolite.
|
-
- HY-D0186S7
-
|
|
Endogenous Metabolite
|
Infection
|
|
2'-Deoxyuridine- 13C, 15N2 is the 13C and 15N labeled 2'-Deoxyuridine[1]. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxudine[2].
|
-
- HY-D0199S
-
|
|
Endogenous Metabolite
|
Others
|
|
Adenosine- 15N5 5′-diphosphate (disodium salt) is the 15N labeled Adenosine 5'-diphosphate disodium salt[1].
|
-
- HY-I0626S1
-
|
|
Endogenous Metabolite
|
Others
|
|
Cytosine- 13C, 15N2 is the 13C and 15N labeled Cytosine[1]. Cytosine is one of the four main bases found in DNA and RNA. Cytosine modifications exhibit circadian oscillations that are involved in epigenetic diversity and aging[2][3].
|
-
- HY-I0960S1
-
|
|
Endogenous Metabolite
|
Cancer
|
|
Uracil- 13C4 is the 13C labeled Uracil[1]. Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA[2].
|
-
- HY-I0960S2
-
|
|
Endogenous Metabolite
|
Cancer
|
|
Uracil- 13C is the 13C labeled Uracil[1]. Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA[2].
|
-
- HY-I0960S3
-
|
|
Endogenous Metabolite
|
Cancer
|
|
Uracil- 13C4, 15N2 is the 13C and 15N labeled Uracil[1]. Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA[2].
|
-
- HY-I0960S5
-
|
|
Endogenous Metabolite
|
Cancer
|
|
Uracil- 15N2 is the 15N labeled Uracil[1]. Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA[2].
|
-
- HY-N0090S3
-
-
- HY-N0091S7
-
|
Purin-6-ol-15N4; Sarcine-15N4
|
Endogenous Metabolite
|
Others
|
|
Hypoxanthine- 15N4 is the 15N labeled Hypoxanthine[1]. Hypoxanthine, a purine derivative, is a potential free radical generator and could be used as an indicator of hypoxia[2].
|
-
- HY-N0097S3
-
|
DL-Guanosine-15N5; Vernine-15N5
|
HSV
Endogenous Metabolite
|
Infection
|
|
Guanosine- 15N5 is the 15N labeled Guanosine[1]. Guanosine (DL-Guanosine) is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. Guanosine possesses anti-HSV activity[2].
|
-
- HY-N0098S2
-
|
p-Vanillin-13C6; m-Methoxy-p-hydroxybenzaldehyde-13C6; p-Hydroxy-m-methoxybenzaldehyde-13C6
|
Endogenous Metabolite
|
Others
|
|
Vanillin- 13C6 is the 13C labeled Vanillin[1]. Vanillin (p-Vanillin) is a single molecule extracted from vanilla beans and also a popular odor used widely in perfume, food and medicine[2][3].
|
-
- HY-N0098S3
-
|
|
Endogenous Metabolite
|
Others
|
|
Vanillin- 13C is the 13C labeled Vanillin[1]. Vanillin (p-Vanillin) is a single molecule extracted from vanilla beans and also a popular odor used widely in perfume, food and medicine[2][3].
|
-
- HY-N0157S1
-
|
6-Carboxyuracil-13C,15N2 monohydrate; Vitamin B13-13C,15N2 monohydrate
|
Nucleoside Antimetabolite/Analog
Endogenous Metabolite
|
Metabolic Disease
|
|
Orotic acid- 13C, 15N2 (monohydrate) is the 13C and 15N labeled Orotic acid[1]. Orotic acid (6-Carboxyuracil), a precursor in biosynthesis of pyrimidine nucleotides and RNA, is released from the mitochondrial dihydroorotate dehydrogenase (DHODH) for conversion to UMP by the cytoplasmic UMP synthase enzyme. Orotic acid is a marker for measurement in routine newborn screening for urea cycle disorders. Orotic acid can induce hepatic steatosis and hepatomegaly in rats[2][3][4].
|
-
- HY-N0304S1
-
|
Levodopa-13C6; 3,4-Dihydroxyphenylalanine-13C6
|
Dopamine Receptor
Endogenous Metabolite
|
Neurological Disease
|
|
L-DOPA- 13C6 is the 13C-labled L-DOPA . L-DOPA (Levodopa) is an orally active metabolic precursor of neurotransmitters dopamine. L-DOPA can cross the blood-brain barrier and is converted into dopamine in the brain. L-DOPA has anti-allodynic effects and the potential for Parkinson's disease .
|
-
- HY-N0304S2
-
|
|
Dopamine Receptor
Endogenous Metabolite
|
Neurological Disease
|
|
L-DOPA- 13C is the 13C labeled L-DOPA[1]. L-DOPA (Levodopa) is an orally active metabolic precursor of neurotransmitters dopamine. L-DOPA can cross the blood-brain barrier and is converted into dopamine in the brain. L-DOPA has anti-allodynic effects and the potential for Parkinson's disease[2][3][4].
|
-
- HY-N0305S2
-
|
5-ALA-13C hydrochloride; δ-Aminolevulinic acid-13C hydrochloride; 5-Amino-4-oxopentanoic acid-13C hydrochloride
|
Apoptosis
Autophagy
Mitophagy
Endogenous Metabolite
|
Metabolic Disease
|
|
5-Aminolevulinic acid- 13C (hydrochloride) is the 13C labeled 5-Aminolevulinic acid hydrochloride[1]. 5-Aminolevulinic acid hydrochloride (5-ALA hydrochloride) is an intermediate in heme biosynthesis in the body and the universal precursor of tetrapyrroles[2][3].
|
-
- HY-N0305S3
-
|
5-ALA-13C-1 hydrochloride; δ-Aminolevulinic acid-13C-1 hydrochloride; 5-Amino-4-oxopentanoic acid-13C-1 hydrochloride
|
Apoptosis
Autophagy
Mitophagy
Endogenous Metabolite
|
Metabolic Disease
|
|
5-Aminolevulinic acid- 13C-1 (5-ALA- 13C-1) hydrochloride is the 13C labeled 5-Aminolevulinic acid hydrochloride . 5-Aminolevulinic acid hydrochloride (5-ALA hydrochloride) is an intermediate in heme biosynthesis in the body and the universal precursor of tetrapyrroles .
|
-
- HY-N0378S2
-
-
- HY-N0379S22
-
|
|
Endogenous Metabolite
|
Others
|
|
D-Mannose- 13C6 is a carbohydrate, which plays an important role in human metabolism, especially in the glycosylationof specific proteins[2].
|
-
- HY-N0394S4
-
|
|
Ferroptosis
Endogenous Metabolite
|
Others
|
|
L-Cystine-3,3'- 13C2 is the 13C labeled L-Cystine[1]. L-Cystine is an amino acid and intracellular thiol, which plays a critical role in the regulation of cellular processes[2].
|
-
- HY-N0420S2
-
|
|
Endogenous Metabolite
|
Neurological Disease
|
|
Succinic acid- 13C4 is the 13C labeled Succinic acid[1]. Succinic acid is a potent and orally active anxiolytic agent. Succinic acid is an intermediate product of the tricarboxylic acid cycle. Succinic acid can be used as a precursor of many industrially important chemicals in food, chemical and pharmaceutical industries[2][3].
|
-
- HY-N0420S3
-
|
|
Endogenous Metabolite
|
Neurological Disease
|
|
Butanedioic acid- 13C2 is the 13C labeled Succinic acid[1]. Succinic acid is a potent and orally active anxiolytic agent. Succinic acid is an intermediate product of the tricarboxylic acid cycle. Succinic acid can be used as a precursor of many industrially important chemicals in food, chemical and pharmaceutical industries[2][3].
|
-
- HY-N0420S4
-
|
|
Endogenous Metabolite
|
Neurological Disease
|
|
Succinic acid- 13C2 is the 13C labeled Succinic acid[1]. Succinic acid is a potent and orally active anxiolytic agent. Succinic acid is an intermediate product of the tricarboxylic acid cycle. Succinic acid can be used as a precursor of many industrially important chemicals in food, chemical and pharmaceutical industries[2][3].
|
-
- HY-N0470S8
-
|
|
Endogenous Metabolite
Virus Protease
|
Infection
|
|
L-Lysine- 13C6 hydrochloride is the 13C labeled L-Lysine hydrochloride[1]. L-lysine hydrochloride is an essential amino acid for humans with various benefits including treating herpes, increasing calcium absorption, reducing diabetes-related illnesses and improving gut health[2][3][4].
|
-
- HY-N0473S16
-
|
|
Endogenous Metabolite
|
Neurological Disease
|
|
L-Tyrosine- 13C, 15N is the 13C and 15N labeled L-Tyrosine[1]. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex[2].
|
-
- HY-N0543S
-
|
5-Ureidohydantoin-13C2,15N4
|
Imidazoline Receptor
Endogenous Metabolite
|
Cancer
|
|
Allantoin- 13C2, 15N4 is the 13C and 15N labeled Allantoin[1]. Allantoin is a skin conditioning agent that promotes healthy skin, stimulates new and healthy tissue growth[2].
|
-
- HY-N0623S10
-
|
|
Endogenous Metabolite
|
Metabolic Disease
Cancer
|
|
L-Phenylalanine,Indole- 15N is the 15N labeled L-Tryptophan[1]. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[2].
|
-
- HY-N0658S6
-
|
|
Endogenous Metabolite
|
Others
|
|
L-Threonine- 13C4 is the 13C labeled L-Threonine[1]. L-Threonine is a natural amino acid, can be produced by microbial fermentation, and is used in food, medicine, or feed[2].
|
-
- HY-N0666S10
-
|
[3-13C]Aspartic acid
|
Endogenous Metabolite
|
Cardiovascular Disease
|
|
L-Aspartic acid- 13C-1 is the deuterium labeled L-Aspartic acid[1]. L-Aspartic acid is is an amino acid, shown to be a suitable proagent for colon-specific agent deliverly[2][3].
|
-
- HY-N1150S8
-
|
DThyd-13C10,15N2; NSC-13C10,15N2
|
DNA/RNA Synthesis
Endogenous Metabolite
Orthopoxvirus
|
Cancer
|
|
Thymidine- 13C10, 15N2 is the 13C and 15N labeled Thymidine[1]. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication[2][3][4].
|
-
- HY-N1150S9
-
|
DThyd-15N2; NSC-15N2
|
DNA/RNA Synthesis
Endogenous Metabolite
Orthopoxvirus
|
Cancer
|
|
Thymidine- 15N2 is the 15N labeled Thymidine[1]. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication[2][3][4].
|
-
- HY-N1380S2
-
-
- HY-N1428S3
-
|
|
Apoptosis
Endogenous Metabolite
Antibiotic
|
Cancer
|
|
Citric acid- 13C3 is the 13C labeled Citric acid[1]. Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid causes renal toxicity in mice[2][3][4].
|
-
- HY-N2362S5
-
|
DL-2-Aminopropionic acid-15N
|
Endogenous Metabolite
|
Metabolic Disease
|
|
DL-Alanine- 15N is the 15N labeled DL-Alanine[1]. DL-alanine, an amino acid, is the racemic compound of L- and D-alanine. DL-alanine is employed both as a reducing and a capping agent, used with silver nitrate aqueous solutions for the production of nanoparticles. DL-alanine can be used for the research of transition metals chelation, such as Cu(II), Zn(II), Cd(11). DL-alanine, a sweetener, is classed together with glycine, and sodium saccharin. DL-alanine plays a key role in the glucose-alanine cycle between tissues and liver[2][3][4][5][6][7].
|
-
- HY-N7032S1
-
|
UDP-D-Glucose-13C6 disodium
|
P2Y Receptor
Endogenous Metabolite
|
Neurological Disease
|
|
Uridine 5′-diphosphoglucose- 13C6 (disodium) is the 13C labeled Uridine 5′-diphosphoglucose disodium salt[1]. Uridine 5′-diphosphoglucose disodium salt (UDP-D-Glucose disodium salt) is the precursor of glucose-containing oligosaccharides, polysaccharides, glycoproteins, and glycolipids in animal tissues and in some microorganisms. Uridine-5′-diphosphoglucose is an agonist of the P2Y14 receptor, a neuroimmune system GPCR[2].
|
-
- HY-W001132S1
-
-
- HY-W001132S2
-
-
- HY-W001132S3
-
-
- HY-W005355S2
-
-
- HY-W005355S9
-
-
- HY-W006057AS16
-
|
|
Endogenous Metabolite
|
Others
|
|
Sodium 3-methyl-2-oxobutanoate- 13C5 is the 13C labeled Sodium 3-methyl-2-oxobutanoate[1]. Sodium 3-methyl-2-oxobutanoate is a precursor of pantothenic acid in Escherichia coli[2][3][4].
|
-
- HY-W006057AS17
-
|
|
Endogenous Metabolite
|
Others
|
|
3-Methyl-2-oxobutanoic acid- 13C2 is the 13C labeled Sodium 3-methyl-2-oxobutanoate[1]. Sodium 3-methyl-2-oxobutanoate is a precursor of pantothenic acid in Escherichia coli[2][3][4].
|
-
- HY-W007941S1
-
-
- HY-W008807S
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Phosphoenolpyruvic acid (potassium)- 13C2 is the 13C labeled Phosphoenolpyruvic acid (potassium)[1]. Potassium 1-carboxyvinyl hydrogenphosphate is an endogenous metabolite.
|
-
- HY-W008848S
-
-
- HY-W008848S1
-
-
- HY-W008849S
-
-
- HY-W009162S
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Cytidine 5′-monophosphate- 15N3 (disodium) is the 15N labeled Cytidine 5'-monophosphate disodium[1]. Cytidine 5'-monophosphate (5'-Cytidylic acid) disodium is a nucleotide which is used as a monomer in RNA. Cytidine 5'-monophosphate disodium consists of the nucleobase cytosine, the pentose sugar ribose, and the phosphate group[2].
|
-
- HY-W009216S
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
2'-Deoxycytidine-5'-monophosphoric acid- 15N3 is the 15N labeled 2'-Deoxycytidine-5'-monophosphoric acid[1]. 2'-Deoxycytidine-5'-monophosphoric acid is an endogenous metabolite.
|
-
- HY-W009296S1
-
-
- HY-W009597S
-
-
- HY-W010184S
-
-
- HY-W010388S
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Creatine- 13C is the 13C labeled Creatine[1]. Creatine, an endogenous amino acid derivative, plays an important role in cellular energy, especially in muscle and brain[2].
|
-
- HY-W010407S2
-
-
- HY-W010450S2
-
|
|
Endogenous Metabolite
|
Cancer
|
|
Thymine- 15N2 is the 15N labeled Thymine[1]. Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a Km of 2.3 μM[2].
|
-
- HY-W010450S3
-
|
|
Endogenous Metabolite
|
Cancer
|
|
Thymine- 13C is the 13C labeled Thymine[1]. Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a Km of 2.3 μM[2].
|
-
- HY-W010712S1
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
Fmoc-His(Trt)-OH- 15N3 is the 15N labeled Fmoc-His(Trt)-OH[1]. Fmoc-His(Trt)-OH has trityl (Trt) group to protect the side-chain of His. Fmoc-His(Trt)-OH has Fmoc group to protect -αNH2. Fmoc-His(Trt)-OH can be used for solid phase synthesis of peptides, providing protection against racemization and by-product formation[2].
|
-
- HY-W011012S2
-
-
- HY-W011090S
-
|
CMP-13C9,15N3
|
Isotope-Labeled Compounds
|
Others
|
|
((2R,3S,4R,5R)-5-(4-Amino-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate- 13C9, 15N3 (sodium) is the 13C and 15N labeled Sodium ((2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate[1].
|
-
- HY-W011540S
-
|
|
Endogenous Metabolite
|
Cancer
|
|
8-Hydroxy-2'-deoxyguanosine- 15N5 is the 15N labeled 8-Hydroxy-2'-deoxyguanosine[1]. 8-Hydroxy-2'-deoxyguanosine is a critical biomarker of oxidative stress and carcinogenesis[2].
|
-
- HY-W011683S6
-
|
|
Endogenous Metabolite
|
Others
|
|
2'-Deoxyadenosine monohydrate- 13C10, 15N5 (hydrate) is the 13C and 15N labeled 2'-Deoxyadenosine monohydrate[1]. 2'-Deoxyadenosine monohydrate is a deoxyribonucleoside. A building block in the chemical synthesis.
|
-
- HY-W011683S7
-
|
|
Endogenous Metabolite
|
Others
|
|
2'-Deoxyadenosine monohydrate- 15N5 is the 15N labeled 2'-Deoxyadenosine monohydrate[1]. 2'-Deoxyadenosine monohydrate is a deoxyribonucleoside. A building block in the chemical synthesis.
|
-
- HY-W012684S
-
-
- HY-W012926S
-
|
5,6-Dihydrouracil-13C4,15N2
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Dihydrouracil- 13C4, 15N2 is the 13C and 15N labeled Dihydrouracil[1]. Dihydrouracil (5,6-Dihydrouracil), a metabolite of Uracil, can be used as a marker for identification of dihydropyrimidine dehydrogenase (DPD)-deficient[2][3].
|
-
- HY-W013059S
-
|
DA-CE phosphoramidite-13C10,15N5
|
DNA/RNA Synthesis
|
Others
|
|
DMT-dA(bz) Phosphoramidite- 13C10, 15N5 is the 13C and 15N labeled DMT-dA(bz) Phosphoramidite[1]. DMT-dA(bz) Phosphoramidite is typically used in the synthesis of DNA[2].
|
-
- HY-W013059S1
-
|
DA-CE phosphoramidite-15N5
|
DNA/RNA Synthesis
|
Others
|
|
DMT-dA(bz) Phosphoramidite- 15N5 is the 15N labeled DMT-dA(bz) Phosphoramidite[1]. DMT-dA(bz) Phosphoramidite is typically used in the synthesis of DNA[2].
|
-
- HY-W013061S10
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Propane-1,2,3-triyl tripalmitate- 13C is the 13C labeled Propane-1,2,3-triyl tripalmitate[1]. Propane-1,2,3-triyl tripalmitate is an endogenous metabolite.
|
-
- HY-W013068S
-
|
|
DNA/RNA Synthesis
|
Others
|
|
DMT-dT Phosphoramidite- 13C10, 15N2 is the 13C and 15N labeled DMT-dT Phosphoramidite[1]. DMT-dT Phosphoramidite is typically used in the synthesis of DNA[2].
|
-
- HY-W013068S1
-
|
|
DNA/RNA Synthesis
|
Others
|
|
DMT-dT Phosphoramidite- 15N2 is the 15N labeled DMT-dT Phosphoramidite[1]. DMT-dT Phosphoramidite is typically used in the synthesis of DNA[2].
|
-
- HY-W013159S
-
|
dGMP-13C10,15N5
|
Endogenous Metabolite
|
Metabolic Disease
|
|
2'-Deoxyguanosine 5'-monophosphate- 13C10, 15N5 (disodium) is the 13C and 15N labeled 2'-Deoxyguanosine 5'-monophosphate disodium[1]. 2'-Deoxyguanosine 5'-monophosphate disodium (5′-dGMP disodium) is a mononucleotide having guanine as the nucleobase. 2'-Deoxyguanosine 5'-monophosphate disodium is a nucleic acid guanosine triphosphate (GTP) derivative[2].
|
-
- HY-W013175S2
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
Uridine 5'-monophosphate- 13C9, 15N2 (disodium) is the 13C and 15N labeled Uridine 5'-monophosphate disodium salt[1]. Uridine 5'-monophosphate disodium salt is component used for RNA synthesis[2].
|
-
- HY-W013636S
-
|
|
Tyrosinase
Endogenous Metabolite
|
Others
|
|
2-Ketoglutaric acid- 13C5 is the 13C labeled 2-Ketoglutaric acid[1]. 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC50=15 mM)[2].
|
-
- HY-W014633S1
-
-
- HY-W015213S
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Adenine monohydrochloride hemihydrate- 15N5 is the 15N labeled Adenine monohydrochloride hemihydrate[1]. Adenine monohydrochloride hemihydrate is an endogenous metabolite.
|
-
- HY-W015410S
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Disodium succinate-13C2 is the 13C labeled Disodium succinate[1]. Disodium succinate is the disodium salt of Succinic acid. Succinic acid is an intermediate product of the tricarboxylic acid cycle, as well as one of fermentation products of anaerobic metabolism[2].
|
-
- HY-W015851S
-
|
3-Hydroxybutyric acid-13C sodium
|
Endogenous Metabolite
|
Metabolic Disease
|
|
3-Hydroxybutanoic acid-13C- 13C (sodium) is the 13C labeled 3-Hydroxybutanoic acid sodium (HY-W010452). 3-Hydroxybutyric acid sodium (β-Hydroxybutyric acid sodium) is a metabolite that is elevated in type I diabetes. 3-Hydroxybutyric acid sodium can modulate the properties of membrane lipids .
|
-
- HY-W015913S3
-
|
|
Endogenous Metabolite
Reactive Oxygen Species
|
Metabolic Disease
|
|
Sodium 2-oxopropanoate- 13C is the 13C labeled Sodium 2-oxopropanoate[1]. Sodium 2-oxopropanoate (Sodium pyruvate), a three-carbon metabolite of Glucose, is a compound produced in the glycolytic pathway. Sodium 2-oxopropanoate is a free radical scavenger that can scavenge ROS[2][3].
|
-
- HY-W015913S4
-
|
|
Endogenous Metabolite
Reactive Oxygen Species
|
Metabolic Disease
|
|
2-Oxopropanoate- 13C5 (sodium) is the 13C labeled Sodium 2-oxopropanoate[1]. Sodium 2-oxopropanoate (Sodium pyruvate), a three-carbon metabolite of Glucose, is a compound produced in the glycolytic pathway. Sodium 2-oxopropanoate is a free radical scavenger that can scavenge ROS[2][3].
|
-
- HY-W016145S
-
-
- HY-W016433S
-
|
|
DNA/RNA Synthesis
|
Others
|
|
2-Aminofluorene- 13C is the 13C labeled 2-Aminofluorene[1]. 2-Aminofluorene is a synthetic chemical insecticide. 2-Aminofluorene is a genotoxin. 2-Aminofluorene can be used in the research of DNA adduct structure, DNA repair, carcinogenesis, and mutagenesis[2][3][4].
|
-
- HY-W016812S
-
-
- HY-W017163S
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
7-Methylxanthine-2,4,5,6- 13C4, 1,3- 15N2 (with variable 15N labeling at N9) is the 13C and 15N labeled 7-Methylxanthine[1]. 7-Methylxanthine, a methyl derivative of xanthine, is one of the purine components in urinary calculi[2].
|
-
- HY-W017387S1
-
|
Sodium 4-methyl-2-oxopentanoate-13C2; 2-Ketoisocaproic acid-13C2 sodium salt
|
Isotope-Labeled Compounds
|
Others
|
|
Sodium α-ketoisocaproic acid- 13C2 is the 13C labeled Sodium α-ketoisocaproic acid[1].
|
-
- HY-W017387S2
-
|
Sodium 4-methyl-2-oxopentanoate-13C5; 2-Ketoisocaproic acid-13C5 sodium salt
|
Isotope-Labeled Compounds
|
Others
|
|
Sodium α-ketoisocaproic acid- 13C5 is the 13C labeled Sodium α-ketoisocaproic acid[1].
|
-
- HY-W017443S4
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
L-Asparagine-1,2,3,4- 13C4 (monohydrate) is the 13C labeled L-Asparagine (monohydrate)[1]. L-Asparagine monohydrate ((-)-Asparagine monohydrate) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue.
|
-
- HY-W017455S1
-
-
- HY-W017522S1
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Adipic acid- 13C6 is the 13C labeled Adipic acid[1]. Adipic acid is found to be associated with HMG-CoA lyase deficiency, carnitine-acylcarnitine translocase deficiency, malonyl-Coa decarboxylase deficiency, and medium Chain acyl-CoA dehydrogenase deficiency, which are inborn errors of metabolism[2].
|
-
- HY-W017522S3
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Adipic acid- 13C is the 13C labeled Adipic acid[1]. Adipic acid is found to be associated with HMG-CoA lyase deficiency, carnitine-acylcarnitine translocase deficiency, malonyl-Coa decarboxylase deficiency, and medium Chain acyl-CoA dehydrogenase deficiency, which are inborn errors of metabolism[2].
|
-
- HY-W018603S
-
-
- HY-W018772S15
-
|
|
Endogenous Metabolite
|
Inflammation/Immunology
|
|
D-Ribose(mixture of isomers)- 13C5 isomers)- 13C5 is the 13C labeled D-Ribose(mixture of isomers)[1]. D-Ribose(mixture of isomers) is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose(mixture of isomers) is active in protein glycation, induces NF-κB inflammation in a RAGE-dependent manner[1].
|
-
- HY-W021400S
-
-
- HY-W021448S1
-
|
|
Endogenous Metabolite
|
Others
|
|
Glycocyamine- 15N, 13C2 is the 13C and 15N labeled Glycocyamine[1]. Glycocyamine (Guanidinoacetic acid), a precursor of creatine, is a replacement of dietary arginine and could support overall energy homeostasis of the bird[2].
|
-
- HY-W028026S
-
-
- HY-W035903S
-
-
- HY-W041171S
-
|
|
Endogenous Metabolite
|
Others
|
|
3-Chloro-L-tyrosine- 13C6 is the 13C labeled 3-Chloro-L-tyrosine[1]. 3-Chloro-L-tyrosine is a specific marker of myeloperoxidase-catalyzed oxidation, and is markedly elevated in low density lipoprotein isolated from human atherosclerotic intima[2].
|
-
- HY-W050145S2
-
|
1,6-Anhydro-β-D-glucopyranose-13C6; 1,6-Anhydro-β-D-glucose-13C6
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Levoglucosan- 13C6 is the 13C labeled Levoglucosan[1]. Levoglucosan (1,6-Anhydro-β-D-glucopyranose) is an anhydrosugar produced through glucan pyrolysis and is widely found in nature[2].
|
-
- HY-W088065S
-
-
- HY-W096993S1
-
|
Tetrapropylammonium bromide-15N
|
Isotope-Labeled Compounds
|
Others
|
|
TPABr (Tetrapropylammonium bromide)- 15N is the 15N labeled TPABr (Tetrapropylammonium bromide) .
|
-
- HY-W105272S
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
2′-Deoxyadenosine 5′-monophosphate- 13C10, 15N5 (disodium) is the 13C and 15N labeled 2′-Deoxyadenosine 5′-monophosphate disodium[1]. 2′-Deoxyadenosine 5′-monophosphate disodium, a nucleic acid AMP derivative, is a deoxyribonucleotide found in DNA. 2′-Deoxyadenosine 5′-monophosphate disodium can be used to study adenosine-based interactions during DNA synthesis and DNA damage[2].
|
-
- HY-W105860S
-
-
- HY-W110705S
-
-
- HY-W243018S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
1,2:5,6-Di-O-isopropylidene-a-D-glucofuranose-1,2,3,4,5,6- 13C6 is the 13C labeled (3aS,5R,6R,6aS)-5-((S)-2,2-Dimethyl-1,3-dioxolan-4-yl)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-6-ol[1].
|
-
- HY-W251598S
-
-
- HY-W344468S
-
-
- HY-W392933S
-
-
- HY-Y0261AS1
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
Ammonium sulphate,≥99.0%,AR- 15N2 is the deuterium labeled Ammonium sulphate,≥99.0%,AR[1]. Ammonium sulphate,≥99.0%,AR is an inorganic sulfate salt used for molecular biology[2].
|
-
- HY-Y0262BS
-
-
- HY-Y0264S2
-
|
|
Bacterial
Endogenous Metabolite
|
Infection
|
|
4-Hydroxybenzoic acid- 13C is the 13C labeled 4-Hydroxybenzoic acid[1]. 4-Hydroxybenzoic acid, a phenolic derivative of benzoic acid, could inhibit most gram-positive and some gram-negative bacteria, with an IC50 of 160 μg/mL[2].
|
-
- HY-Y0271S2
-
|
|
Endogenous Metabolite
|
Cardiovascular Disease
|
|
Urea- 13C, 15N2 is the 13C and 15N labeled Urea[1]. Urea is a powerful protein denaturant via both direct and indirect mechanisms[1]. A potent emollient and keratolytic agent[2]. Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function[3]. Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry.
|
-
- HY-Y0287AS
-
-
- HY-Y0338S1
-
-
- HY-Y0442S
-
-
- HY-Y0504S2
-
|
Hegzadesil-15N; Trimethylamine hydrochloric acid-15N; Trimethylamine monohydrochloride-15N
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Trimethylammonium chloride- 15N is the 15N labeled Trimethylammonium chloride[1]. Trimethylammonium chloride is an endogenous metabolite.
|
-
- HY-Y0546S2
-
-
- HY-Y0781S1
-
|
Acetylformic acid-13C
|
Endogenous Metabolite
|
Others
|
|
Pyruvic acid- 13C is the 13C labeled Pyruvic acid[1]. Pyruvic acid is an intermediate metabolite in the metabolism of carbohydrates, proteins, and fats[2].
|
-
- HY-Y0781S3
-
|
Acetylformic acid-13C-2 sodium
|
Endogenous Metabolite
|
Others
|
|
Pyruvic acid- 13C-2 (sodium) is the 13C labeled Pyruvic acid[1]. Pyruvic acid is an intermediate metabolite in the metabolism of carbohydrates, proteins, and fats[2].
|
-
- HY-Y0827S
-
-
- HY-Y0836S
-
|
1,4-Diethyl butanedioate-1,2,3,4-13C4
|
Isotope-Labeled Compounds
|
Metabolic Disease
|
|
Diethyl succinate- 13C4 is the 13C labeled Diethyl succinate[1]. Diethyl succinate (Diethyl Butanedioate) is used at physiological pH and crosses biological membranes, incorporates into cells in tissue culture and is metabolized by the TCA cycle. Diethyl succinate is known to be non-toxic and used in fragrances and flavoring[2].
|
-
- HY-Y0842S2
-
|
|
Endogenous Metabolite
|
Others
|
|
Glycine- 13C, 15N is the 13C and 15N labeled Formamide[1]. Formamide is an amide derived from formic acid and has been used as solvent for many ionic compounds.
|
-
- HY-Y0842S3
-
|
|
Endogenous Metabolite
|
Others
|
|
Formamide- 15N is the 15N labeled Formamide[1]. Formamide is an amide derived from formic acid and has been used as solvent for many ionic compounds.
|
-
- HY-Y0847S
-
-
- HY-Y0989S3
-
-
- HY-Y1055S
-
|
|
DNA/RNA Synthesis
Endogenous Metabolite
|
Cancer
|
|
Guanine- 13C is the 13C labeled Guanine[1]. Guanine (2-Aminohypoxanthine) is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds.
|
-
- HY-Y1055S1
-
|
|
DNA/RNA Synthesis
Endogenous Metabolite
|
Cancer
|
|
Guanine- 13C, 15N2 is the 13C and 15N labeled Guanine[1]. Guanine (2-Aminohypoxanthine) is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds.
|
-
- HY-Y1093S1
-
|
|
Bacterial
|
Others
|
|
Ethyl acetoacetate- 13C4 is the 13C labeled Ethyl acetoacetate[1]. Ethyl acetoacetate (Ethyl acetylacetate) is an ester widely used as an intermediate in the synthesis of many varieties of compounds[2][3][4]. Ethyl acetoacetate is an inhibitor of bacterial biofilm[5].
|
-
- HY-Y1093S3
-
|
|
Bacterial
|
Others
|
|
Ethyl acetoacetate- 13C is the 13C labeled Ethyl acetoacetate[1]. Ethyl acetoacetate (Ethyl acetylacetate) is an ester widely used as an intermediate in the synthesis of many varieties of compounds[2][3][4]. Ethyl acetoacetate is an inhibitor of bacterial biofilm[5].
|
-
- HY-Y1117S1
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
Melamine-13C3 is the 13C labeled Melamine[1]. Melamine is a metabolite of cyromazine. Melamine is a intermediate for the synthesis of melamine resin and plastic materials[2].
|
-
- HY-Y1169S1
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
Fmoc-Asp(OtBu)-OH- 13C4, 15N is the 13C and 15N labeled Fmoc-Asp(OtBu)-OH[1]. Fmoc-Asp(OtBu)-OH (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate) is a aspartate derivative containing amine protecting group Fmoc. Fmoc-Asp(OtBu)-OH can be used for peptide synthesis[2].
|
-
- HY-Y1213S
-
-
- HY-Y1220S
-
-
- HY-Y1352S
-
-
- HY-Y1352S1
-
-
- HY-Y1636S1
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
Fmoc-Arg(Pbf)-OH- 13C6 is the 13C labeled Fmoc-Arg(Pbf)-OH[1]. Fmoc-Arg(Pbf)-OH is an arginine derivative containing amine protecting group Fmoc. Fmoc-Arg(Pbf)-OH is a building block for the introduction of Arg into SPPS (Solid-Phase Peptide Synthesis)[2].
|
-
- HY-103447S1
-
|
Mycotoxin F2-13C18; Toxin F2-13C18
|
Isotope-Labeled Compounds
|
Others
|
|
Zearalenone- 13C18 (Mycotoxin F2- 13C18; Toxin F2- 13C18) is the 13C labeled Zearalenone (HY-103447) . Zearalenone is a mycotoxin produced mainly by fungi belonging to the genus Fusarium in foods and feeds. Possess oestrogenic activity in pigs, cattle and sheep, with low acute toxicity. Causes precocious development of mammae and other estrogenic effects in young gilts .
|
-
- HY-N6779S
-
|
Terinin-13C7
|
Isotope-Labeled Compounds
|
Infection
|
|
Patulin- 13C7 (Terinin- 13C7) is the 13C labeled Patulin (HY-N6779) . Patulin (Terinin) is a mycotoxin produced by fungi including the Aspergillus, Penicillium, and Byssochlamys species, is suspected to be clastogenic, mutagenic, teratogenic and cytotoxic. Patulin induces autophagy-dependent apoptosis through lysosomal-mitochondrial axis, and causes DNA damage .
|
-
- HY-152072S
-
-
- HY-N6685S1
-
|
|
Isotope-Labeled Compounds
|
Cardiovascular Disease
|
|
3-Acetyldeoxynivalenol- 13C17 is the 13C labeled 3-Acetyldeoxynivalenol (HY-N6685) . 3-Acetyldeoxynivalenol, a trichothecene mycotoxin deoxynivalenol (DON) acetylated derivative , is a blood-brain barrier (BBB) permeable mycotoxin .
|
-
- HY-N6683S1
-
|
|
Isotope-Labeled Compounds
|
Cancer
|
|
15-Acetyl-deoxynivalenol- 13C17 is the 13C labeled 15-Acetyl-deoxynivalenol (HY-N6683) . 15-Acetyl-deoxynivalenol is a highly toxic trichothecene found in cereals, and a metabolite of deoxynivalenol, exhibits toxicity to HepG2 cells .
|
-
- HY-B0421S2
-
|
Mycophenolate-13C17
|
Isotope-Labeled Compounds
Flavivirus
|
Cancer
|
|
Mycophenolic acid-13C17 (Mycophenolate-13C17) is the 13C labeled Mycophenolic acid (HY-B0421). Mycophenolic acid is a potent uncompetitive inosine monophosphate dehydrogenase (IMPDH) inhibitor with an EC50 of 0.24 μM. Mycophenolic acid demonstrates antiviral effects against a wide range of RNA viruses including influenza. Mycophenolic acid is an immunosuppressive agent. Antiangiogenic and antitumor effects.
|
-
- HY-N6801S
-
|
|
Isotope-Labeled Compounds
|
Infection
|
|
Nivalenol- 13C15 is the 13C labeled Nivalenol (HY-N6801) . Nivalenol, classified as type B trichotecenes toxins produced by Fusarium graminearum, is a fungal metabolite present in agricultural product . Nivalenol induces cell death through caspase-dependent mechanisms and via the intrinsic apoptotic pathway. Nivalenol affects the immune system, causes emesis, growth retardation, reproductive disorders and has a haematotoxic/myelotoxic effect .
|
-
- HY-N6746S1
-
|
NSC 186-13C13
|
Isotope-Labeled Compounds
Apoptosis
Bacterial
Autophagy
|
Infection
Neurological Disease
Cancer
|
|
Citrinin- 13C13 (NSC 186- 13C13) is the 13C labeled Citrinin (HY-N6746). Citrinin (NSC 186) is a mycotoxin that causes food contamination and has different toxic effects. Citrinin is an effective oral anticancer agent. Citrinin has various regulatory effects on mouse immune system, including regulating the number of immune cells, inducing apoptosis and autophagy of immune cells, altering toll-like receptor expression and cytokine production. Citrinin can induce oxidative stress and lead to early apoptosis of oocytes. Low doses of Citrinin have neuroprotective effects against glutamate-induced excitotoxicity in rat cortical neurons. In addition, Citrinin also has antibacterial activity .
|
-
- HY-N6719S
-
|
|
Isotope-Labeled Compounds
|
Infection
|
|
Fumonisin B1- 13C34 is the 13C labeled Fumonisin B1 (HY-N6719) . Fumonisin B1 is a mycotoxin produced from Fusarium moniliforme. Fumonisin B1 is a potent inhibitor of sphingosine N-acyltransferase (ceramide synthase) and disrupts de novo sphingolipid biosynthesis. Fumonisin B1 is the most abundant and toxic fumonisin .
|
-
- HY-N6723S
-
|
|
Isotope-Labeled Compounds
|
Infection
|
|
Fumonisin B2- 13C34 is the 13C labeled Fumonisin B2 (HY-N6723) . Fumonisin B2, a mycotoxin produced by Fusarium moniliforme in various grains, is a potent inhibitor of sphingosine N-acyltransferase (ceramide synthase) and disrupts de novo sphingolipid biosynthesis .
|
-
- HY-N6726S
-
|
|
Isotope-Labeled Compounds
|
Cancer
|
|
Fumonisin B3- 13C34 is the 13C labeled Fumonisin B3 (HY-N6726) . Fumonisin B3 is a mycotoxin derived from fusarium fungi, a member of fumonisins .
|
-
- HY-A0181S1
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
Adenosine monophosphate- 15N5 (dilithium) is the 15N labeled Adenosine monophosphate (HY-A0181) . Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction .
|
-
- HY-N6786S
-
|
|
Isotope-Labeled Compounds
|
Cancer
|
|
Ochratoxin B- 13C20 is 13C-labeled Ochratoxin B (HY-N6786). Ochratoxin B, a secondary metabolite of Aspergillus ochraceus, is the nonchlorinated analogue of the mycotoxin Ochratoxin A. Ochratoxin B has been shown to reduce the toxic effects of Ochratoxin A, and it is one of the most potent renal carcinogens in rodents .
|
-
- HY-108213S
-
|
5'-IMP-13C10,15N4 dilithium; IMP-13C10,15N4 dilithium; Inosine 5'-dihydrogen phosphate-13C10,15N4 dilithium
|
Isotope-Labeled Compounds
|
Metabolic Disease
|
|
Inosinic acid- 13C10, 15N4 dilithium (5'-IMP-13C10,15N4 (dilithium); IMP-13C10,15N4 (dilithium); Inosine 5'-(dihydrogen phosphate)-13C10,15N4 (dilithium)) is 13C- and 15N-labeled Inosinic acid (HY-108213). Inosinic acid is an endogenous metabolite .
|
-
- HY-108213S1
-
|
5'-IMP15N4 dilithium; IMP-15N4 dilithium; Inosine 5'-dihydrogen phosphate-15N4 dilithium
|
Isotope-Labeled Compounds
|
Metabolic Disease
|
|
Inosinic acid- 15N4 dilithium (5'-IMP-15N4 (dilithium); IMP-15N4 (dilithium); Inosine 5'-(dihydrogen phosphate)-15N4 (dilithium)) is 15N-labeled Inosinic acid (HY-108213). Inosinic acid is an endogenous metabolite .
|
-
- HY-13948BS
-
|
Angiotensin II-13C6,15N TFA; Ang II-13C6,15N TFA; DRVY(I-13C6,15N)HPF TFA
|
Isotope-Labeled Compounds
|
Cancer
|
|
Angiotensin II human- 13C6, 15N TFA (Ang II- 13C6, 15N TFA) is 13C- and 15N-labeled Angiotensin II human (TFA) (HY-13948B). Angiotensin II human (Angiotensin II) TFA is a vasoconstrictor and a major bioactive peptide of the renin/angiotensin system. Angiotensin II human TFA plays a central role in regulating human blood pressure, which is mainly mediated by interactions between Angiotensin II and the G-protein-coupled receptors (GPCRs) Angiotensin II type 1 receptor (AT1R) and Angiotensin II type 2 receptor (AT2R). Angiotensin II human TFA stimulates sympathetic nervous stimulation, increases aldosterone biosynthesis and renal actions .
|
-
- HY-N0055S
-
|
3-O-Caffeoylquinic acid-13C3; Heriguard-13C3; NSC-407296-13C3
|
Isotope-Labeled Compounds
|
Cancer
|
|
Chlorogenic acid- 13C3 (Heriguard- 13C3; NSC-407296- 13C3) is 13C- and 15N-labeled Chlorogenic acid (HY-N0055). Chlorogenic acid is a major phenolic compound in Lonicera japonica Thunb.. It plays several important and therapeutic roles such as antioxidant activity, antibacterial, hepatoprotective, cardioprotective, anti-inflammatory, antipyretic, neuroprotective, anti-obesity, antiviral, anti-microbial, anti-hypertension .
|
-
- HY-P5168S
-
|
|
Isotope-Labeled Compounds
|
Infection
|
|
GPSVFPLAPSSK- 13C6 is the 13C labeled GPSVFPLAPSSK. GPSVFPLAPSSK is an IgG1 signature peptide of anti-SARS-CoV-2 antibodies. GPSVFPLAPSSK can be used for the quantification of the specific isolation of anti-SARS-CoV-2 antibodies .
|
-
- HY-126373S1
-
|
SN-38G-13C6
|
Isotope-Labeled Compounds
|
Others
|
|
SN-38 glucuronide- 13C6 is the 13C labeled SN-38 glucuronide (HY-126373) . SN-38 glucuronide is an inactive metabolite of the cancer agent Irinotecan. Irinotecan is a topoisomerase I inhibitor which can be used for researching colon and rectal cancer .
|
-
- HY-P5190S
-
-
- HY-P5190S1
-
-
- HY-P5201S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
VTSEGAGLQLQK- 13C6, 15N2 is the 13C and 15N labeled VTSEGAGLQLQK. VTSEGAGLQLQK is an amino acid sequence in the C-terminal region of recombinant human alpha-acid glucosidase (rhGAA). VTSEGAGLQLQK can be used to bind anti-drug antibodies (ADA) in plasma and quantitatively analyze the therapeutic effect .
|
-
- HY-136457S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
2-NP-AHD- 13C3 is the 13C labled 2-NP-AHD (HY-136457) . 2-NP-AHD is a 2-nitrophenyl derivative of AHD (a metabolite of nitrofurans type of antibiotics), can be used as indicator of the illegal usage of nitrofuran agents .
|
-
- HY-B0226S
-
|
Nitrofural-13C,15N2
|
Isotope-Labeled Compounds
|
Infection
|
|
Nitrofurazone- 13C, 15N2 (Nitrofural- 13C, 15N2) is the 13C and 15N labled Nitrofurazone (HY-B0226) . Nitrofurazone is a potential antibiotic that can be used topically to treat wounds, burns, ulcers and skin infections to combat various microorganisms and to prepare surfactants . Nitrofurazone may affect the ecosystem function in Marine environment and affect the functional processes of epiphytic fauna .
|
-
- HY-104026S3
-
|
|
Isotope-Labeled Compounds
|
Cancer
|
|
L-Kynurenine- 13C4, 15N-1 is the 13C and 15N labled L-Kynurenine (HY-104026) . L-Kynurenine is a metabolite of the amino acid L-tryptophan. L-Kynurenine is an aryl hydrocarbon receptor agonist.
|
-
- HY-W018772S16
-
|
|
Isotope-Labeled Compounds
|
Inflammation/Immunology
|
|
D-Ribose-1,2- 13C2 is the 13C labled D-Ribose(mixture of isomers) (HY-W018772) . D-Ribose(mixture of isomers) is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose(mixture of isomers) is active in protein glycation, induces NF-κB inflammation in a RAGE-dependent manner .
|
-
- HY-128748S4
-
-
- HY-A0132S12
-
|
N-Acetyl-2-amino-2-deoxy-D-glucose-13C6
|
Isotope-Labeled Compounds
|
Metabolic Disease
|
|
N-Acetyl-D-glucosamine- 13C6 (N-Acetyl-2-amino-2-deoxy-D-glucose- 13C6) is the 13C labled N-Acetyl-D-glucosamine (HY-A0132) . N-Acetyl-D-Glucosamine (N-Acetyl-2-amino-2-deoxy-D-glucose) is a monosaccharide derivative of glucose.
|
-
- HY-B1842S
-
-
- HY-W015824S5
-
-
- HY-Y0262S1
-
|
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Others
|
|
Oxalic acid- 13C2 is the deuterium labeled Oxalic acid, 99% (HY-Y0262) . Oxalic Acid is a strong dicarboxylic acid occurring in many plants and vegetables and can be used as an analytical reagent and general reducing agent .
|
-
- HY-W110148S
-
-
- HY-W051624S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
(Rac)-2-Aminothiazoline-4-carboxylic acid- 13C, 15N2 is the deuterium labeled 2-Amino-4,5-dihydrothiazole-4-carboxylic acid (HY-W051624) .
|
-
- HY-W040055S
-
|
D-(+)-Neopterin-13C5; D-erythro-Neopterin-13C5
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Others
|
|
Neopterin- 13C5 (D-(+)-Neopterin- 13C5; D-erythro-Neopterin- 13C5) is the deuterium labeled Neopterin (HY-W040055) . Neopterin (D-(+)-Neopterin), a catabolic product of guanosine triphosphate (GTM), serves as a marker of cellular immune system activation .
|
-
- HY-P4596S1
-
-
- HY-P4596S
-
-
- HY-14605S
-
|
(R)-AGN1135-13C3 mesylate; TVP1012-13C3 mesylate
|
Isotope-Labeled Compounds
Autophagy
Monoamine Oxidase
Apoptosis
|
Others
|
|
Rasagiline- 13C3 ((R)-AGN1135- 13C3; TVP1012- 13C3) mesylate is the deuterium labeled Rasagiline (mesylate) (HY-14605) . Rasagiline (R-AGN1135) mesylate is a highly potent selective irreversible mitochondrial monoamine oxidase (MAO) inhibitor with IC50s of 4.43 nM and 412 nM for rat brain MAO B and A activity, respectively .
|
-
- HY-13417S
-
|
Acadesine-13C2,15N; AICA Riboside-13C2,15N
|
Isotope-Labeled Compounds
Endogenous Metabolite
YAP
AMPK
Mitophagy
Autophagy
|
Others
|
|
AICAR- 13C2, 15N (Acadesine- 13C2, 15N; AICA Riboside- 13C2, 15N) is the 13C and 15N labeled AICAR (HY-13417) . AICAR (Acadesine) is an adenosine analog and a AMPK activator. AICAR regulates the glucose and lipid metabolism, and inhibits proinflammatory cytokines and iNOS production. AICAR is also an autophagy, YAP and mitophagy inhibitor .
|
-
- HY-133968S1
-
|
Ostreasterol-13C
|
Isotope-Labeled Compounds
Acyltransferase
|
Others
|
|
24-Methylenecholesterol- 13C (Ostreasterol- 13C) is the 13C labeled 24-Methylenecholesterol (HY-133968) . 24-Methylenecholesterol (Ostreasterol), a natural marine sterol, stimulates cholesterol acyltransferase in human macrophages. 24-Methylenecholesterol possess anti-aging effects in yeast. 24-methylenecholesterol enhances honey bee longevity and improves nurse bee physiology .
|
-
- HY-112537S1
-
-
- HY-100807S1
-
|
|
Isotope-Labeled Compounds
iGluR
Endogenous Metabolite
|
Others
|
|
Quinolinic acid- 13C7 is the 13C labeled Quinolinic acid (HY-100807) . Quinolinic acid is an endogenous N-methyl-D-aspartate (NMDA) receptor agonist synthesized from L-tryptophan via the kynurenine pathway and thereby has the potential of mediating N-methyl-D-aspartate neuronal damage and dysfunction .
|
-
- HY-B0510S3
-
|
|
Isotope-Labeled Compounds
Antibiotic
Bacterial
Antifolate
Influenza Virus
|
Others
|
|
Trimethoprim- 13C3 is the deuterium labeled Trimethoprim (HY-B0510) . Trimethoprim is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim has the potential for the research of urinary tract infections, Shigellosis and Pneumocystis pneumonia. Trimethoprim can inhibit infection of Influenza A virus in chick embryo when combinated with zinc .
|
-
- HY-A0090S
-
|
|
Isotope-Labeled Compounds
Antibiotic
Bacterial
|
Others
|
|
Nitrofurantoin- 13C3 is the 13C labeled Nitrofurantoin (HY-A0090) . Nitrofurantoin is a potent and orally active broad-spectrum beta-lactamase antimicrobial agent. Nitrofurantoin acts as an antibiotic and can be used for the study of urinary tract infections (UTIs), including cystitis and kidney infections .
|
-
- HY-Y1117S2
-
|
|
Isotope-Labeled Compounds
Drug Metabolite
|
Others
|
|
Melamine- 15N3, 13C3 is a 13C- and 15N-labeled Melamine (HY-Y1117). Melamine is a metabolite of cyromazine. Melamine is a intermediate for the synthesis of melamine resin and plastic materials .
|
-
- HY-Y0051S
-
|
2-Hydroxymethyl-5-furfural-13C6; 2-Formyl-5-hydroxymethylfuran-13C6
|
Isotope-Labeled Compounds
Fungal
|
Others
|
|
5-Hydroxymethylfurfural- 13C6 (2-Hydroxymethyl-5-furfural- 13C6; 2-Formyl-5-hydroxymethylfuran- 13C6) is a 13C labeled 5-Hydroxymethylfurfural (HY-Y0051). 5-Hydroxymethylfurfural (2-Hydroxymethyl-5-furfural), derived from Cornus officinalis, inhibits yeast growth and fermentation as stressors.
|
-
- HY-13623S1
-
|
BMS200475-13C2,15N; SQ34676-13C2,15N
|
Isotope-Labeled Compounds
HBV
|
Infection
|
|
Entecavir- 13C2, 15N (BMS200475- 13C2, 15N; SQ34676- 13C2, 15N) is a 13C- and 15N-labeled Entecavir (HY-13623). Entecavir (SQ 34676; BMS 200475) is a potent and selective inhibitor of HBV, with an EC50 of 3.75 nM in HepG2 cell.
|
-
- HY-138253S
-
|
dFdU-13C,15N2; 2',2'-Difluoro-2'-deoxyuridine-13C,15N2
|
Isotope-Labeled Compounds
|
Others
|
|
2′,2′-Difluorodeoxyuridine- 13C, 15N2 (dFdU- 13C, 15N2; 2',2'-Difluoro-2'-deoxyuridine- 13C, 15N2) is a 13C- and 15N-labeled compound.
|
-
- HY-14291S2
-
|
LAF237-13C5,15N; NVP-LAF 237-13C5,15N
|
Isotope-Labeled Compounds
Dipeptidyl Peptidase
Apoptosis
Ferroptosis
|
Metabolic Disease
|
|
Vildagliptin- 13C5, 15N (LAF237- 13C5, 15N; NVP-LAF 237- 13C5, 15N) is a 13C- and 15N-labeled Vildagliptin (HY-14291). Vildagliptin (LAF237) is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC50 of 3.5 nM in human Caco-2 cells. Vildagliptin possesses excellent oral bioavailability and potent antihyperglycemic activity .
|
-
- HY-17427S2
-
-
- HY-17563S1
-
|
Deoxyguanosine-13C10,15N5; Guanine deoxyriboside-13C10,15N5
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Cancer
|
|
2'-Deoxyguanosine- 13C10, 15N5 (Deoxyguanosine- 13C10, 15N5; Guanine deoxyriboside- 13C10, 15N5) is a 13C- and 15N-labeled 2'-Deoxyguanosine (HY-17563).
|
-
- HY-18341S4
-
-
- HY-78131S3
-
|
(±)-Ibuprofen-13C6
|
Isotope-Labeled Compounds
Apoptosis
Parasite
COX
|
Cancer
|
|
Ibuprofen- 13C6 ((±)-Ibuprofen- 13C6) is a 13C labeled Ibuprofen (HY-78131). Ibuprofen ((±)-Ibuprofen) is a potent, orally active, selective COX-1 inhibitor with an IC50 value of 13 μM. Ibuprofen inhibits cell proliferation, angiogenesis, and induces cell apoptosis. Ibuprofen is a nonsteroidal anti-inflammatory agent and a nitric oxide (NO) donor. Ibuprofen ((±)-Ibuprofen) can be used in the research of pain, swelling, inflammation, infection, immunology, cancers .
|
-
- HY-B0139S
-
-
- HY-B0166S8
-
|
L-Ascorbate-1; Vitamin C-13C6-1
|
Isotope-Labeled Compounds
Endogenous Metabolite
Reactive Oxygen Species
Calcium Channel
Apoptosis
|
Cancer
|
|
L-Ascorbic acid- 13C6-1 (L-Ascorbate-1; Vitamin C- 13C6-1) is a 13C labeled L-Ascorbic acid (HY-B0166) . L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor . L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells .
|
-
- HY-B1449S10
-
|
β-Uridine-13C5
|
Isotope-Labeled Compounds
|
Cancer
|
|
Uridine- 13C5 (β-Uridine- 13C5) is a 13C labeled Uridine (HY-B1449). Uridine (β-Uridine) is a nucleoside compound consisting of uracil and a ribose ring, which are linked by a β-N1- glycosyl bond.
|
-
- HY-B1449S9
-
-
- HY-P5537S
-
-
- HY-P5538S
-
-
- HY-W007376S
-
|
3-Formylindole-13C3
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Others
|
|
Indole-3-carboxaldehyde- 13C (3-Formylindole- 13C) is a 13C labeled Indole-3-carboxaldehyde (HY-W007376). Indole-3-carboxaldehyde (3-Formylindole), a banlangen extract, is the product of the oxidative degradation of indole-3-acetic acid (IAA) by crude enzyme preparations from etiolated pea seedlings. Indole-3-carboxaldehyde (3-Formylindole) is a biochemical used to prepare analogs of the indole phytoalexin cyclobrassinin .
|
-
- HY-W009362AS
-
-
- HY-W009362S
-
|
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Others
|
|
DL-Isocitric acid- 13C4 (trisodium salt) is a 13C labeled DL-Isocitric acid (trisodium salt) (HY-W009362). DL-Isocitric acid trisodium salt is an endogenous metabolite. DL-Isocitric acid trisodium salt is a substrate in the citric acid cycle. DL-Isocitric acid trisodium salt can be used as a marker for determining the composition of isocitrates in fruit products, including fruit juices.
|
-
- HY-13078S
-
|
GDC-0973-13C66 racemate; XL518-13C6 racemate
|
Isotope-Labeled Compounds
MEK
|
Others
|
|
Cobimetinib- 13C6 (GDC-0973- 13C6; XL518- 13C6) racemate is the deuterium labeled Cobimetinib (racemate) (HY-13078) . Cobimetinib racemate (GDC-0973 racemate; XL518 racemate) is the racemate of Cobimetinib. Cobimetinib is a potent and selective MEK inhibitor .
|
-
- HY-B0221S
-
|
|
Isotope-Labeled Compounds
Antibiotic
Fungal
Parasite
Bacterial
|
Cancer
|
|
Amphotericin B- 13C6 is 13C labeled Amphotericin B (HY-B0221). Amphotericin B is a polyene antifungal agent against a wide variety of fungal pathogens. It binds irreversibly to ergosterol, resulting in disruption of membrane integrity and ultimately cell death.
|
-
- HY-W777535S
-
-
- HY-B1654S
-
|
FAD-13C5 ammonium
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Cardiovascular Disease
|
|
Flavin adenine dinucleotide- 13C5 (FAD- 13C5) ammonium is 13C labeled Flavin adenine dinucleotide (HY-B1654). Flavin adenine dinucleotide (FAD) is a redox cofactor, more specifically a prosthetic group of a protein, involved in several important enzymatic reactions in metabolism.
|
-
- HY-W777456
-
-
- HY-W777457
-
-
- HY-W777535
-
-
- HY-N0349S1
-
|
Methyl 4-hydroxybenzoate-13C6
|
Isotope-Labeled Compounds
Bacterial
Endogenous Metabolite
|
Infection
|
|
Methyl Paraben- 13C6 (Methyl 4-hydroxybenzoate- 13C6) is a 13C labeled Methyl Paraben (HY-N0349) . Methyl Paraben, isolated from the barks of Tsuga dumosa the methyl ester of p-hydroxybenzoic acid, is a standardized chemical allergen. Methyl Paraben is a stable, non-volatile compound used as an antimicrobial preservative in foods, agents and cosmetics. The physiologic effect of Methyl Paraben is by means of increased histamine release, and cell-mediated immunity .
|
-
- HY-W013636S3
-
|
Alpha-Ketoglutaric acid-13C
|
Isotope-Labeled Compounds
Endogenous Metabolite
Tyrosinase
|
Others
|
|
2-Ketoglutaric acid- 13C (Alpha-Ketoglutaric acid- 13C) is a 13C labeled 2-Ketoglutaric acid (HY-W013636) . 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC50=15 mM) .
|
-
- HY-A0181BS
-
|
AMP-13C10,15N5 disodium
|
Endogenous Metabolite
|
Infection
|
|
Adenosine monophosphate-13C10,15N5 (disodium) is the sodium salt form of Adenosine monophosphate-13C10,15N5. Adenosine monophosphate is a key cellular metabolite that regulates energy homeostasis and signal transduction .
|
-
- HY-B0863S3
-
|
|
Isotope-Labeled Compounds
Apoptosis
Autophagy
Necroptosis
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Neurological Disease
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Glyphosate- 13C2, 15N is the 13C and 15N labled Glyphosate (HY-B0863). Glyphosate is an herbicidal derivative of the amino acid glycine. Glyphosate targets and blocks a plant metabolic pathway not found in animals, the shikimate pathway, required for the synthesis of aromatic amino acids in plants .
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-
- HY-N0832S1A
-
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Isotope-Labeled Compounds
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Metabolic Disease
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L-Histidine- 13C6, 15N3 hydrochloride is the 13C and 15N labled L-Histidine (HY-N0832). L-Histidine is an essential amino acid for infants. L-Histidine is an inhibitor of mitochondrial glutamine transport.
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- HY-B0228S11
-
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Adenine riboside-15N5; D-Adenosine-15N5
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Isotope-Labeled Compounds
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Cancer
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Adenosine- 15N5 (Adenine riboside- 15N5; D-Adenosine- 15N5) is the 15N labled Adenosine (HY-B0228). Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation .
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-
- HY-12726S1
-
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Isotope-Labeled Compounds
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Cancer
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Liproxstatin-1- 15N is the 15N labled Liproxstatin-1 (HY-12726). Liproxstatin-1 is a potent ferroptosis inhibitor and inhibits ferroptotic cell death (IC50=22 nM) .
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-
- HY-12726S
-
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Isotope-Labeled Compounds
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Cancer
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Liproxstatin-1- 13C6 is the 13C labled Liproxstatin-1 (HY-12726). Liproxstatin-1 is a potent ferroptosis inhibitor and inhibits ferroptotic cell death (IC50=22 nM) .
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-
- HY-B0141S7
-
-
- HY-W016814S
-
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cis-Aconitic acid-13C6
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Isotope-Labeled Compounds
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Others
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(Z)-Aconitic acid- 13C6 is the 13C-labeled (Z)-Aconitic acid (HY-W016814). (Z)-Aconitic acid- 13C6 (cis-Aconitic acid) is the cis-isomer of Aconitic acid. (Z)-Aconitic acid- 13C6 (cis-Aconitic acid) is an intermediate in the tricarboxylic acid cycle produced by the dehydration of citric acid.
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-
- HY-W778203
-
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Hydroxyethanoic acid-13C2
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Isotope-Labeled Compounds
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Others
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Glycolic acid- 13C2 is the 13C-labeled Glycolic acid (HY-W015967). Glycolic acid- 13C2 is an inhibitor of tyrosinase, suppressing melanin formation and lead to a lightening of skin colour.
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-
- HY-N7745S2
-
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Glucopsychosine-13C6; Lyso-Gb1-13C6
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Isotope-Labeled Compounds
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Others
|
|
Glucosylsphingosine- 13C6 is an active compound. Glucosylsphingosine- 13C6 can be used for various studies .
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-
- HY-A0132S13
-
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N-Acetyl-2-amino-2-deoxy-D-glucose-13C8,15N
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Isotope-Labeled Compounds
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Others
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N-Acetyl-D-glucosamine- 13C8, 15N is 13C and 15N labeled N-Acetyl-D-glucosamine (HY-A0132). N-Acetyl-D-glucosamine is a monosaccharide derivative of glucose.
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-
- HY-B1342S3
-
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Vitamin A1-13C3; all-trans-Retinol-13C3
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Isotope-Labeled Compounds
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Others
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|
Vitamin A- 13C3 (Vitamin A1- 13C3; all-trans-Retinol- 13C3) is a 13C-labeled Vitamin A/Vitamin A (HY-B1342). Vitamin A is an endogenous metabolite.
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- HY-D0187S4
-
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GSH-13C; γ-L-Glutamyl-L-cysteinyl-glycine-13C
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Isotope-Labeled Compounds
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Others
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L-Glutathione reduced- 13C (GSH- 13C; γ-L-Glutamyl-L-cysteinyl-glycine- 13C) is 13C-labeled L-Glutathione reduced (HY-D0187). L-Glutathione reduced is an endogenous antioxidant and oxygen free radical scavenger.
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-
- HY-D0187S6
-
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GSH-15N; γ-L-Glutamyl-L-cysteinyl-glycine-15N
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Isotope-Labeled Compounds
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Others
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L-Glutathione reduced- 15N (GSH- 15N; γ-L-Glutamyl-L-cysteinyl-glycine- 15N) is 15N-labeled L-Glutathione reduced (HY-D0187). L-Glutathione reduced (GSH; γ-L-Glutamyl-L-cysteinyl-glycine) is an endogenous antioxidant that scavenges oxygen free radicals.
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-
- HY-N7092S22
-
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D(-)-Fructose-13C3
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Isotope-Labeled Compounds
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Others
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|
D-Fructose- 13C3 is 13C-labeled D-Fructose (HY-N7092). D-Fructose (D(-)-Fructose) is a natural monosaccharide found in many plants.
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-
- HY-N7092S23
-
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D(-)-Fructose-13C3-1
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Isotope-Labeled Compounds
|
Others
|
|
D-Fructose- 13C3-1 is 13C-labeled D-Fructose (HY-N7092). D-Fructose (D(-)-Fructose) is a natural monosaccharide found in many plants.
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-
- HY-N7092S24
-
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D(-)-Fructose-13C4
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Isotope-Labeled Compounds
|
Others
|
|
D-Fructose- 13C4 is 13C-labeled D-Fructose (HY-N7092). D-Fructose (D(-)-Fructose) is a natural monosaccharide found in many plants.
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-
- HY-W751098
-
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Isotope-Labeled Compounds
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Others
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|
Aldosterone- 13C3 is a 13C-labeled Aldosterone (HY-113313). Aldosterone is a primary mineralocorticoid and steroid hormone.
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-
- HY-W751099
-
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Isotope-Labeled Compounds
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Others
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|
Corticosterone- 13C3 is a 13C-labeled corticosterone (HY-B1618). Corticosterone (17-Deoxycortisol) is an orally available glucocorticoid that can regulate limbic system neurons and has good immunosuppressive activity.
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-
- HY-W770183
-
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Isotope-Labeled Compounds
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Others
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Uric acid- 13C3 is 13C-labeled Uric acid (HY-B2130). Uric acid is the end product of purine metabolism in the human body. Uric acid can scavenge reactive oxygen species (ROS), such as singlet oxygen and peroxynitrite, and inhibit lipid peroxidation.
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-
- HY-112675S
-
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Isotope-Labeled Compounds
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Others
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4-Octyl itaconate- 13C5-1 is 13C-labeled 4-Octyl itaconate (HY-112675). Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.
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-
- HY-W015851S2
-
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(R)-(-)-3-Hydroxybutanoic acid-13C4 sodium; (R)-3-Hydroxybutyric acid-13C4 sodium
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Isotope-Labeled Compounds
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Others
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|
(R)-3-Hydroxybutanoic acid-13C4 (sodium) is an active compound. (R)-3-Hydroxybutanoic acid-13C4 (sodium) can be used for kinds of research.
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-
- HY-13407S
-
|
BL 193-13C2
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Bcl-2 Family
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Others
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|
Gossypol-13C2 (BL 193-13C2) is an active compound. Gossypol-13C2 can be used for kinds of research.
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-
- HY-150651S
-
-
- HY-B0190S1
-
|
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Ser/Thr Protease
Apoptosis
SARS-CoV
|
Cardiovascular Disease
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Nafamostat formate salt- 13C6 is the 13C labeled Nafamostat. Nafamostat, a synthetic serine protease inhibitor, is an anticoagulant. Nafamostat supresses T cell auto-reactivity by decreasing granzyme activity and CTL cytolysis. Nafamostat blocks activation of SARS-CoV-2 .
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-
- HY-B1462S1
-
|
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Cytochrome P450
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Inflammation/Immunology
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Chlorzoxazone- 13C is the 13C labeled Chlorzoxazone[1]. Chlorzoxazone is a centrally acting muscle relaxant used to treat muscle spasm and the resulting pain or discomfort[2].
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-
- HY-W334800S2
-
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L-threo-2,6-Diaminopimelic acid-13C7
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Isotope-Labeled Compounds
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Others
|
|
(2S,6S)-2,6-Diaminoheptanedioic acid- 13C7 (L-threo-2,6-Diaminopimelic acid- 13C7) is 13C-labeled (2S,6S)-2,6-diaminoheptanedioic acid (HY-W334800).
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-
- HY-W334800S
-
|
L-threo-2,6-Diaminopimelic acid-13C7,15N2
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Isotope-Labeled Compounds
|
Others
|
|
(2S,6S)-2,6-Diaminoheptanedioic acid- 13C7, 15N2 (L-threo-2,6-Diaminopimelic acid- 13C7, 15N2) is 13C and 15N-labeled (2S,6S)-2,6-diaminoheptanedioic acid (HY-W334800).
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-
- HY-W334800S1
-
|
L-threo-2,6-Diaminopimelic acid-15N2
|
Isotope-Labeled Compounds
|
Others
|
|
(2S,6S)-2,6-Diaminoheptanedioic acid- 15N2 (L-threo-2,6-Diaminopimelic acid- 15N2) is 15N labeled (2S,6S)-2,6-diaminoheptanedioic acid (HY-W334800).
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-
- HY-128746S
-
-
- HY-128746S1
-
-
- HY-W393970S2
-
|
5'-Deoxyguanylic acid-13C10 dilithium
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Isotope-Labeled Compounds
|
Others
|
|
2′-Deoxyguanosine 5′-monophosphate- 13C10 (5'-Deoxyguanylic acid- 13C10) dilithium is 13C-labeled 2′-Deoxyguanosine 5′-monophosphate (HY-W393970).
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-
- HY-W393970S3
-
|
5'-Deoxyguanylic acid-13C10,15N5 dilithium
|
Isotope-Labeled Compounds
|
Others
|
|
2′-Deoxyguanosine 5′-monophosphate- 13C10, 15N5 (5'-Deoxyguanylic acid- 13C10, 15N5) dilithium is 13C and 15N-labeled 2′-Deoxyguanosine 5′-monophosphate (HY-W393970).
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-
- HY-W393970S4
-
|
5'-Deoxyguanylic acid-15N5 dilithium
|
Isotope-Labeled Compounds
|
Others
|
|
2′-Deoxyguanosine 5′-monophosphate- 15N5 (5'-Deoxyguanylic acid- 15N5) dilithium is 15N labeled 2′-Deoxyguanosine 5′-monophosphate (HY-W393970).
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-
- HY-W040329S1
-
-
- HY-W040329S
-
-
- HY-W016009S3
-
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Isotope-Labeled Compounds
Endogenous Metabolite
|
Metabolic Disease
|
|
2'-Deoxyadenosine-5'-monophosphate- 13C10 dilithium is 13C-labeled 2'-Deoxyadenosine-5'-monophosphate (HY-W016009). 2′-Deoxyadenosine 5′-monophosphate, a nucleic acid AMP derivative, is a deoxyribonucleotide found in DNA. 2′-Deoxyadenosine 5′-monophosphate can be used to study adenosine-based interactions during DNA synthesis and DNA damage.
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-
- HY-W016009S4
-
|
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Isotope-Labeled Compounds
Endogenous Metabolite
|
Metabolic Disease
|
|
2'-Deoxyadenosine-5'-monophosphate- 13C10, 15N5 dilithium is 13C and 15N-labeled 2'-Deoxyadenosine-5'-monophosphate (HY-W016009). 2′-Deoxyadenosine 5′-monophosphate, a nucleic acid AMP derivative, is a deoxyribonucleotide found in DNA. 2′-Deoxyadenosine 5′-monophosphate can be used to study adenosine-based interactions during DNA synthesis and DNA damage.
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-
- HY-W016009S2
-
|
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Metabolic Disease
|
|
2'-Deoxyadenosine-5'-monophosphate- 15N5 dilithium is 15N labeled 2'-Deoxyadenosine-5'-monophosphate (HY-W016009). 2′-Deoxyadenosine 5′-monophosphate, a nucleic acid AMP derivative, is a deoxyribonucleotide found in DNA. 2′-Deoxyadenosine 5′-monophosphate can be used to study adenosine-based interactions during DNA synthesis and DNA damage.
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-
- HY-136648S5
-
|
dATP-13C10 dilithium
|
Isotope-Labeled Compounds
Endogenous Metabolite
DNA/RNA Synthesis
|
Others
|
|
2'-Deoxyadenosine-5'-triphosphate- 13C10 (dATP- 13C10) dilithium is 13C-labeled 2'-Deoxyadenosine-5'-triphosphate (HY-136648). 2'-Deoxyadenosine-5'-triphosphate (dATP) is a nucleotide used in cells for DNA synthesis (or replication), as a substrate of DNA polymerase.
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-
- HY-136648S1
-
|
dATP-13C10,15N5 dilithium
|
Isotope-Labeled Compounds
Endogenous Metabolite
DNA/RNA Synthesis
|
Others
|
|
2'-Deoxyadenosine-5'-triphosphate- 13C10, 15N5 (dATP- 13C10, 15N5) dilithium is 13C and 15N-labeled 2'-Deoxyadenosine-5'-triphosphate (HY-136648). 2'-Deoxyadenosine-5'-triphosphate (dATP) is a nucleotide used in cells for DNA synthesis (or replication), as a substrate of DNA polymerase.
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-
- HY-136648S4
-
|
dATP-15N5 dilithium
|
Isotope-Labeled Compounds
Endogenous Metabolite
DNA/RNA Synthesis
|
Others
|
|
2'-Deoxyadenosine-5'-triphosphate- 15N5 (dATP- 15N5) dilithium is 15N labeled 2'-Deoxyadenosine-5'-triphosphate (HY-136648). 2'-Deoxyadenosine-5'-triphosphate (dATP) is a nucleotide used in cells for DNA synthesis (or replication), as a substrate of DNA polymerase.
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-
- HY-D0184S5
-
|
Deoxycytidine-13C9; Cytosine deoxyriboside-13C9; Deoxyribose cytidine-13C9
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Others
|
|
2'-Deoxycytidine- 13C9 (Deoxycytidine- 13C9; Cytosine deoxyriboside- 13C9; Deoxyribose cytidine- 13C9) is 13C-labeled 2'-Deoxycytidine (HY-D0184). 2'-Deoxycytidine, a deoxyribonucleoside, could inhibit biological effects of Bromodeoxyuridine (Brdu).
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-
- HY-D0184S3
-
|
Deoxycytidine-13C9,15N3; Cytosine deoxyriboside-13C9,15N3; Deoxyribose cytidine-13C9,15N3
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Others
|
|
2'-Deoxycytidine- 13C9, 15N3 (Deoxycytidine- 13C9, 15N3; Cytosine deoxyriboside- 13C9, 15N3; Deoxyribose cytidine- 13C9, 15N3) is 13C and 15N-labeled 2'-Deoxycytidine (HY-D0184). 2'-Deoxycytidine, a deoxyribonucleoside, could inhibit biological effects of Bromodeoxyuridine (Brdu).
|
-
- HY-W009216S1
-
-
- HY-17563S2
-
|
Deoxyguanosine-13C10; Guanine deoxyriboside-13C10
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Cancer
|
|
2'-Deoxyguanosine- 13C10 (Deoxyguanosine- 13C10; Guanine deoxyriboside- 13C10) is 13C-labeled 2'-Deoxyguanosine (HY-17563). 2'-Deoxyguanosine (Deoxyguanosine) is deoxyguanosine.
|
-
- HY-17563S4
-
|
Deoxyguanosine-15N5; Guanine deoxyriboside-15N5
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Cancer
|
|
2'-Deoxyguanosine- 15N5 (Deoxyguanosine- 15N5; Guanine deoxyriboside- 15N5) is 15N labeled 2'-Deoxyguanosine (HY-17563). 2'-Deoxyguanosine (Deoxyguanosine) is deoxyguanosine.
|
-
- HY-134178S
-
-
- HY-N5134S1
-
|
5'-GMP-13C10 dilithium; 5'-guanosine monophosphate-13C10 dilithium
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Metabolic Disease
|
|
5'-Guanylic acid- 13C10 (5'-GMP- 13C10 dilithium; 5'-guanosine monophosphate- 13C10) dilithium is 13C-labeled 5'-Guanylic acid (HY-N5134). 5'-Guanylic acid (5'-GMP) is involved in several metabolic disorders, including the AICA-ribosiduria pathway, adenosine deaminase deficiency, adenine phosphoribosyltransferase deficiency (aprt), and the 2-hydroxyglutric aciduria pathway.
|
-
- HY-N5134S5
-
|
5'-GMP-13C10,15N5 dilithium; 5'-guanosine monophosphate-13C10,15N5 dilithium
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Metabolic Disease
|
|
5'-Guanylic acid- 13C10, 15N5 (5'-GMP- 13C10, 15N5 dilithium; 5'-guanosine monophosphate- 13C10, 15N5) dilithium is 13C and 15N-labeled 5'-Guanylic acid (HY-N5134). 5'-Guanylic acid (5'-GMP) is involved in several metabolic disorders, including the AICA-ribosiduria pathway, adenosine deaminase deficiency, adenine phosphoribosyltransferase deficiency (aprt), and the 2-hydroxyglutric aciduria pathway.
|
-
- HY-N5134S2
-
|
5'-GMP-15N5 dilithium; 5'-guanosine monophosphate-15N5 dilithium
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Metabolic Disease
|
|
5'-Guanylic acid- 15N5 (5'-GMP- 15N5 dilithium; 5'-guanosine monophosphate- 15N5) dilithium is 15N labeled 5'-Guanylic acid (HY-N5134). 5'-Guanylic acid (5'-GMP) is involved in several metabolic disorders, including the AICA-ribosiduria pathway, adenosine deaminase deficiency, adenine phosphoribosyltransferase deficiency (aprt), and the 2-hydroxyglutric aciduria pathway.
|
-
- HY-154741S
-
-
- HY-W042357S4
-
-
- HY-W042357S6
-
|
|
Isotope-Labeled Compounds
DNA/RNA Synthesis
|
Others
|
|
Ac-rC Phosphoramidite- 13C9, 15N3 is 13C and 15N-labeled Ac-rC Phosphoramidite (HY-W042357). Ac-rC Phosphoramidite is used for the oligoribonucleotide phosphorodithioate modification (PS2-RNA).
|
-
- HY-W042357S
-
-
- HY-W042357S1
-
-
- HY-W042357S2
-
-
- HY-B0152S3
-
|
6-Aminopurine-13C5; Vitamin B4-13C5
|
Isotope-Labeled Compounds
DNA/RNA Synthesis
Endogenous Metabolite
|
Cancer
|
|
Adenine- 13C5 (6-Aminopurine- 13C5; Vitamin B4- 13C5) is 13C-labeled Adenine (HY-B0152). Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA.
Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis.
|
-
- HY-B0152S2
-
|
6-Aminopurine-13C5,15N5; Vitamin B4-13C5,15N5
|
Isotope-Labeled Compounds
DNA/RNA Synthesis
Endogenous Metabolite
|
Cancer
|
|
Adenine- 13C5,15C5 (6-Aminopurine- 13C5,15C5; Vitamin B4- 13C5,15C5) is 13C-labeled Adenine (HY-B0152). Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis.
|
-
- HY-B0152S4
-
|
6-Aminopurine-15N5; Vitamin B4-15N5
|
Isotope-Labeled Compounds
DNA/RNA Synthesis
Endogenous Metabolite
|
Cancer
|
|
Adenine- 15N5 (6-Aminopurine- 15N5; Vitamin B4- 15N5) is 15N labeled Adenine (HY-B0152). Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA.
Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis.
|
-
- HY-A0181S3
-
|
AMP-13C10 dilithium
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Others
|
|
Adenosine monophosphate- 13C10 (AMP- 13C10) dilithium is 13C-labeled Adenosine monophosphate (HY-A0181). Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction.
|
-
- HY-B0228S13
-
-
- HY-128417S4
-
-
- HY-W014375S2
-
-
- HY-W014375S4
-
-
- HY-B2176S2
-
|
Adenosine 5'-triphosphate-13C dilithium
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Metabolic Disease
Inflammation/Immunology
|
|
ATP- 13C (Adenosine 5'-triphosphate- 13C) dilithium is 13C-labeled ATP (HY-B2176). ATP (Adenosine 5'-triphosphate) is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation.
|
-
- HY-B2176S6
-
|
Adenosine 5'-triphosphate-13C10 dilithium
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Metabolic Disease
Inflammation/Immunology
|
|
ATP- 13C10 (Adenosine 5'-triphosphate- 13C10) dilithium is 13C-labeled ATP (HY-B2176). ATP (Adenosine 5'-triphosphate) is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation.
|
-
- HY-B2176S5
-
|
Adenosine 5'-triphosphate-15N5 dilithium
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Metabolic Disease
Inflammation/Immunology
|
|
ATP- 15N5 (Adenosine 5'-triphosphate- 15N5) dilithium is 15N labeled ATP (HY-B2176). ATP (Adenosine 5'-triphosphate) is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation.
|
-
- HY-W009162S1
-
|
5'-Cytidylic acid-13C9 dilithium; 5'-CMP-13C9 dilithium
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Metabolic Disease
|
|
Cytidine 5′-monophosphate- 13C9 (5'-Cytidylic acid- 13C9 dilithium; 5'-CMP- 13C9) dilithium is 13C-labeled Cytidine 5'-monophosphate (HY-W009162). Cytidine 5'-monophosphate (5'-Cytidylic acid) is a nucleotide which is used as a monomer in RNA. Cytidine 5'-monophosphate consists of the nucleobase cytosine, the pentose sugar ribose, and the phosphate group.
|
-
- HY-W009162S5
-
|
5'-Cytidylic acid-13C9,15N3 dilithium; 5'-CMP-13C9,15N3 dilithium
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Metabolic Disease
|
|
Cytidine 5′-monophosphate- 13C9, 15N3 (5'-Cytidylic acid- 13C9, 15N3 dilithium; 5'-CMP- 13C9, 15N3) dilithium is 13C and 15N-labeled Cytidine 5'-monophosphate (HY-W009162). Cytidine 5'-monophosphate (5'-Cytidylic acid) is a nucleotide which is used as a monomer in RNA. Cytidine 5'-monophosphate consists of the nucleobase cytosine, the pentose sugar ribose, and the phosphate group.
|
-
- HY-W009162S4
-
|
5'-Cytidylic acid-15N3 dilithium; 5'-CMP-15N3 dilithium
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Metabolic Disease
|
|
Cytidine 5′-monophosphate- 15N3 (5'-Cytidylic acid- 15N3 dilithium; 5'-CMP- 15N3) dilithium is 15N labeled Cytidine 5'-monophosphate (HY-W009162). Cytidine 5'-monophosphate (5'-Cytidylic acid) is a nucleotide which is used as a monomer in RNA. Cytidine 5'-monophosphate consists of the nucleobase cytosine, the pentose sugar ribose, and the phosphate group.
|
-
- HY-113400S1
-
|
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Others
|
|
Cytidine diphosphate- 13C9 dilithium is 13C-labeled Cytidine diphosphate (HY-113400). Cytidine diphosphate is a nucleoside diphosphate that acts as a carrier for phosphorylcholine, diacylglycerol, and other molecules during phospholipid synthesis.
|
-
- HY-113400S2
-
|
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Others
|
|
Cytidine diphosphate- 13C9, 15N3 dilithium is 13C and 15N-labeled Cytidine diphosphate (HY-113400). Cytidine diphosphate is a nucleoside diphosphate that acts as a carrier for phosphorylcholine, diacylglycerol, and other molecules during phospholipid synthesis.
|
-
- HY-113400S
-
|
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Others
|
|
Cytidine diphosphate- 15N3 dilithium is 15N labeled Cytidine diphosphate (HY-113400). Cytidine diphosphate is a nucleoside diphosphate that acts as a carrier for phosphorylcholine, diacylglycerol, and other molecules during phospholipid synthesis.
|
-
- HY-125818S3
-
|
Cytidine triphosphate-13C9 dilithium; 5'-CTP-13C9 dilithium
|
Isotope-Labeled Compounds
DNA/RNA Synthesis
Nucleoside Antimetabolite/Analog
Endogenous Metabolite
|
Infection
Cancer
|
|
Cytidine-5'-triphosphate- 13C9 (Cytidine triphosphate- 13C9 dilithium; 5'-CTP- 13C9) dilithium is 13C-labeled Cytidine-5'-triphosphate (HY-125818). Cytidine 5′-triphosphate (Cytidine triphosphate; 5'-CTP) is a nucleoside triphosphate and serves as a building block for nucleotides and nucleic acids, lipid biosynthesis. Cytidine triphosphate synthase can catalyze the formation of cytidine 5′-triphosphate from uridine 5′-triphosphate (UTP). Cytidine 5′-triphosphate is an essential biomolecule?in the de novo?pyrimidine biosynthetic pathway in?T. gondii.
|
-
- HY-125818S6
-
|
Cytidine triphosphate-15N3 dilithium; 5'-CTP-15N3 dilithium
|
Isotope-Labeled Compounds
DNA/RNA Synthesis
Nucleoside Antimetabolite/Analog
Endogenous Metabolite
|
Infection
Cancer
|
|
Cytidine-5'-triphosphate- 15N3 (Cytidine triphosphate- 15N3 dilithium; 5'-CTP- 15N3) dilithium is 15N labeled Cytidine-5'-triphosphate (HY-125818). Cytidine 5′-triphosphate (Cytidine triphosphate; 5'-CTP) is a nucleoside triphosphate and serves as a building block for nucleotides and nucleic acids, lipid biosynthesis. Cytidine triphosphate synthase can catalyze the formation of cytidine 5′-triphosphate from uridine 5′-triphosphate (UTP). Cytidine 5′-triphosphate is an essential biomolecule?in the de novo?pyrimidine biosynthetic pathway in?T. gondii.
|
-
- HY-101400S4
-
-
- HY-101400S2
-
|
dCTP-13C9,15N3 dilithium; 2′-Deoxycytidine-5′-triphosphate-13C9,15N3 dilithium
|
Isotope-Labeled Compounds
Nucleoside Antimetabolite/Analog
DNA/RNA Synthesis
Endogenous Metabolite
|
Metabolic Disease
|
|
Deoxycytidine triphosphate- 13C9, 15N3 (dCTP- 13C9, 15N3 dilithium; 2′-Deoxycytidine-5′-triphosphate- 13C9, 15N3) dilithium is 13C and 15N-labeled Deoxycytidine triphosphate (HY-101400). Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.
|
-
- HY-101400S3
-
-
- HY-138615S2
-
-
- HY-138615S4
-
-
- HY-138615S1
-
-
- HY-138616S3
-
|
2'-Deoxyguanosine-5'-triphosphate-13C10 dilithium
|
Isotope-Labeled Compounds
DNA/RNA Synthesis
Nucleoside Antimetabolite/Analog
|
Infection
Cancer
|
|
dGTP- 13C10 (2'-Deoxyguanosine-5'-triphosphate- 13C10) dilithium is 13C-labeled dGTP (HY-138616). dGTP (2'-Deoxyguanosine-5'-triphosphate), a guanosine nucleotide, can be used in deoxyribonucleic acid synthesis. Guanosine nucleotides (GDP, GTP, dGDP, and dGTP) are highly susceptible to oxidative damage to 8-oxo-GDP (8-O-GDP), 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.
|
-
- HY-138616S4
-
|
2'-Deoxyguanosine-5'-triphosphate-13C10,15N5 dilithium
|
Isotope-Labeled Compounds
DNA/RNA Synthesis
Nucleoside Antimetabolite/Analog
|
Infection
Cancer
|
|
dGTP- 13C10, 15N5 (2'-Deoxyguanosine-5'-triphosphate- 13C10, 15N5) dilithium is 13C and 15N-labeled dGTP (HY-138616). dGTP (2'-Deoxyguanosine-5'-triphosphate), a guanosine nucleotide, can be used in deoxyribonucleic acid synthesis. Guanosine nucleotides (GDP, GTP, dGDP, and dGTP) are highly susceptible to oxidative damage to 8-oxo-GDP (8-O-GDP), 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.
|
-
- HY-138616S
-
|
2'-Deoxyguanosine-5'-triphosphate-155
|
Isotope-Labeled Compounds
DNA/RNA Synthesis
Nucleoside Antimetabolite/Analog
|
Infection
Cancer
|
|
dGTP- 15N5 (2'-Deoxyguanosine-5'-triphosphate- 15N5) dilithium is 15N labeled dGTP (HY-138616). dGTP (2'-Deoxyguanosine-5'-triphosphate), a guanosine nucleotide, can be used in deoxyribonucleic acid synthesis. Guanosine nucleotides (GDP, GTP, dGDP, and dGTP) are highly susceptible to oxidative damage to 8-oxo-GDP (8-O-GDP), 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.
|
-
- HY-B2236S1
-
|
(±)-2,6-Diaminocaproic acid-13C6 hydrochloride
|
Isotope-Labeled Compounds
|
Metabolic Disease
|
|
DL-Lysine- 13C6 hydrochloride ((±)-2,6-Diaminocaproic acid- 13C6 hydrochloride) is 13C-labeled DL-Lysine (HY-B2236). DL-Lysine is a racemic mixture of the D-Lysine and L-Lysine. Lysine is an α-amino acid that is used in the biosynthesis of proteins.
|
-
- HY-B2236S2
-
|
(±)-2,6-Diaminocaproic acid-13C6,15N2 hydrochloride
|
Isotope-Labeled Compounds
|
Metabolic Disease
|
|
DL-Lysine- 13C6, 15N2 hydrochloride ((±)-2,6-Diaminocaproic acid- 13C6, 15N2 hydrochloride) is 13C and 15N-labeled DL-Lysine (HY-B2236). DL-Lysine is a racemic mixture of the D-Lysine and L-Lysine. Lysine is an α-amino acid that is used in the biosynthesis of proteins.
|
-
- HY-B2236S3
-
|
(±)-2,6-Diaminocaproic acid-15N2 hydrochloride
|
Isotope-Labeled Compounds
|
Metabolic Disease
|
|
DL-Lysine- 15N2 hydrochloride ((±)-2,6-Diaminocaproic acid- 15N2 hydrochloride) is 15N labeled DL-Lysine (HY-B2236). DL-Lysine is a racemic mixture of the D-Lysine and L-Lysine. Lysine is an α-amino acid that is used in the biosynthesis of proteins.
|
-
- HY-W013068S2
-
-
- HY-Y1055S4
-
-
- HY-Y1055S2
-
|
|
Isotope-Labeled Compounds
DNA/RNA Synthesis
Endogenous Metabolite
|
Cancer
|
|
Guanine- 13C5, 15N5 is 13C and 15N-labeled Guanine (HY-Y1055). Guanine (2-Aminohypoxanthine) is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds.
|
-
- HY-Y1055S3
-
-
- HY-113066S1
-
|
GDP-13C10 dilithium
|
Isotope-Labeled Compounds
Endogenous Metabolite
Potassium Channel
|
Inflammation/Immunology
|
|
Guanosine 5'-diphosphate- 13C10 (GDP- 13C10) dilithium is 13C-labeled Guanosine 5'-diphosphate (HY-113066). Guanosine 5'-diphosphate (GDP) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K + channel. Guanosine 5'-diphosphate is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate can be used in the research of inflammation, such as anemia of inflammation (AI).
|
-
- HY-113066S3
-
|
GDP-13C10,15N5 dilithium
|
Isotope-Labeled Compounds
Endogenous Metabolite
Potassium Channel
|
Inflammation/Immunology
|
|
Guanosine 5'-diphosphate- 13C10, 15N5 (GDP- 13C10, 15N5) dilithium is 13C and 15N-labeled Guanosine 5'-diphosphate (HY-113066). Guanosine 5'-diphosphate (GDP) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K + channel. Guanosine 5'-diphosphate is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate can be used in the research of inflammation, such as anemia of inflammation (AI).
|
-
- HY-113225S2
-
-
- HY-113225S5
-
-
- HY-113225S3
-
-
- HY-W013724S
-
-
- HY-N0832S1
-
-
- HY-N0086S2
-
|
6-Methyladenosine-13C4; N-Methyladenosine-13C4
|
Isotope-Labeled Compounds
Influenza Virus
Endogenous Metabolite
|
Infection
|
|
N6-Methyladenosine- 13C4 (6-Methyladenosine- 13C4; N-Methyladenosine- 13C4) is 13C-labeled N6-Methyladenosine (HY-N0086). N6-Methyladenosine is the most prevalent internal (non-cap) modification present in the messenger RNA (mRNA) of all higher eukaryotes. N6-Methyladenosine can modifies viral RNAs and has antiviral activities.
|
-
- HY-113061S
-
-
- HY-W048482S2
-
|
DMT-2'O-TBDMS-rU phosphoramidite-13C9
|
Isotope-Labeled Compounds
DNA/RNA Synthesis
|
Others
|
|
rU Phosphoramidite- 13C9 (DMT-2'O-TBDMS-rU phosphoramidite- 13C9) is 13C-labeled rU Phosphoramidite (HY-W048482). rU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
|
-
- HY-W048482S1
-
|
DMT-2'O-TBDMS-rU phosphoramidite-13C9,15N2
|
Isotope-Labeled Compounds
DNA/RNA Synthesis
|
Others
|
|
rU Phosphoramidite- 13C9, 15N2 (DMT-2'O-TBDMS-rU phosphoramidite- 13C9, 15N2) is 13C and 15N-labeled rU Phosphoramidite (HY-W048482). rU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
|
-
- HY-W048482S4
-
|
DMT-2'O-TBDMS-rU phosphoramidite-15N
|
Isotope-Labeled Compounds
DNA/RNA Synthesis
|
Others
|
|
rU Phosphoramidite- 15N (DMT-2'O-TBDMS-rU phosphoramidite- 15N) is 15N labeled rU Phosphoramidite (HY-W048482). rU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
|
-
- HY-W048482S3
-
|
DMT-2'O-TBDMS-rU phosphoramidite-15N2
|
Isotope-Labeled Compounds
DNA/RNA Synthesis
|
Others
|
|
rU Phosphoramidite- 15N2 (DMT-2'O-TBDMS-rU phosphoramidite- 15N2) is 15N labeled rU Phosphoramidite (HY-W048482). rU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
|
-
- HY-W392933S3
-
|
Thymidine-5'-phosphate-13C10 dilithium
|
Isotope-Labeled Compounds
|
Others
|
|
Thymidine 5'-monophosphate- 13C10 (Thymidine-5'-phosphate- 13C10) dilithium is 13C-labeled Thymidine 5'-monophosphate (HY-W392933).
|
-
- HY-W392933S4
-
|
Thymidine-5'-phosphate-13C10,15N2 dilithium
|
Isotope-Labeled Compounds
|
Others
|
|
Thymidine 5'-monophosphate- 13C10, 15N2 (Thymidine-5'-phosphate- 13C10, 15N2) dilithium is 13C and 15N-labeled Thymidine 5'-monophosphate (HY-W392933).
|
-
- HY-W392933S2
-
|
Thymidine-5'-phosphate-15N2 dilithium
|
Isotope-Labeled Compounds
|
Others
|
|
Thymidine 5'-monophosphate- 15N2 (Thymidine-5'-phosphate- 15N2) dilithium is 15N labeled Thymidine 5'-monophosphate (HY-W392933).
|
-
- HY-N1150S11
-
-
- HY-113359AS1
-
-
- HY-113359AS2
-
-
- HY-113359AS3
-
-
- HY-101981S4
-
|
5'-Uridylic acid-13C9 dilithium
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Others
|
|
Uridine 5'-monophosphate- 13C9 (5'- Uridylic acid- 13C9) dilithium is 13C-labeled Uridine 5'-monophosphate (HY-101981). Uridine 5'-monophosphate (5'- Uridylic acid), a monophosphate form of UTP, can be acquired either from a de novo pathway or degradation products of nucleotides and nucleic acids in vivo and is a major nucleotide analogue in mammalian milk.
|
-
- HY-101981S3
-
|
5'-Uridylic acid-13C9,15N2 dilithium
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Others
|
|
Uridine 5'-monophosphate- 13C9, 15N2 (5'- Uridylic acid- 13C9, 15N2) dilithium is 13C and 15N-labeled Uridine 5'-monophosphate (HY-101981). Uridine 5'-monophosphate (5'- Uridylic acid), a monophosphate form of UTP, can be acquired either from a de novo pathway or degradation products of nucleotides and nucleic acids in vivo and is a major nucleotide analogue in mammalian milk.
|
-
- HY-101981S5
-
|
5'-Uridylic acid-15N2 dilithium
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Others
|
|
Uridine 5'-monophosphate- 15N2 (5'-?Uridylic acid- 15N2) dilithium is 15N labeled Uridine 5'-monophosphate (HY-101981). Uridine 5'-monophosphate (5'-?Uridylic acid), a monophosphate form of UTP, can be acquired either from a de novo pathway or degradation products of nucleotides and nucleic acids in vivo and is a major nucleotide analogue in mammalian milk.
|
-
- HY-107372S2
-
-
- HY-107372S4
-
-
- HY-W768291
-
-
![[1-13Cgal]Lactose monohydrate](//file.medchemexpress.eu/product_pic/hy-w768291.gif)
- HY-N0092S4
-
-
- HY-W753983
-
|
Acetylformic acid-13C3
|
Isotope-Labeled Compounds
|
Metabolic Disease
|
|
Pyruvic acid-13C is isotype-labeled compound of Pyruvic acid. Pyruvic acid is an intermediate metabolite in the metabolism of carbohydrates, proteins, and fats .
|
-
- HY-W101298S
-
|
L-Leucyl-13C6,15N-L-isoleucine TFA
|
Isotope-Labeled Compounds
|
Neurological Disease
|
|
(Leu-13C6,15N)-Ile-OH (L-Leucyl-13C6,15N-L-isoleucine) TFA is the deuterium labeled Leu-Ile-OH. Leu-Ile-OH protects against neuronal death by inducing brain-derived neurotrophic factor (BDNF) and glial cell line-derived neurotrophic factor (GDNF) synthesis .
|
-
- HY-111095S1
-
|
(R)-2-Hydroxypropionic acid-13C; D-Lactic acid-13C
|
Isotope-Labeled Compounds
|
Others
|
|
D-(-)-Lactic acid-13C ((R)-2-Hydroxypropionic acid-13C) is a 13C-labeled D-Lactic acid. D-(-)-Lactic acid-13C can be used as an internal standard and can also be used in studies such as metabolic tracing.
|
-
- HY-104026S5
-
-
- HY-111095S2
-
|
(R)-2-Hydroxypropionic acid-13C-1; D-Lactic acid-13C-1
|
Endogenous Metabolite
|
Others
|
|
D-(-)-Lactic acid- 13C-1 is the 13C labeled D-(-)-Lactic acid. D-(-)-Lactic acid is a normal intermediate in the fermentation (oxidation, metabolism) of sugar. D-(-)-Lactic acid is identified to be a competitive inhibitor of ProDH (proline dehydrogenase) in plants .
|
-
- HY-111095S3A
-
|
(R)-2-Hydroxypropionic acid-13C-2 sodium; D-Lactic acid-13C-2 sodium
|
Isotope-Labeled Compounds
|
Others
|
|
D-(-)-Lactic acid-13C-2 (sodium) is a sodium. D-(-)-Lactic acid-13C-2 (sodium) can be used for a variety of biochemical studies.
|
-
- HY-P3003S
-
-
- HY-W008642S
-
|
L-Leucyl-13C6,15N-L-leucine
|
Isotope-Labeled Compounds
|
Others
|
|
(Leu-13C6,15N)-Leu-OH TFA is a C13 and N15 labeled Leu-Leu-OH TFA. Leu-Leu-OH, a Leu derivative, is a dipeptide .
|
-
- HY-B0174AS
-
-
- HY-W585866S
-
-
- HY-157386S
-
-
- HY-N6714S2
-
-
- HY-136406S
-
|
|
Isotope-Labeled Compounds
|
Cancer
|
|
Bongkrekic acid-13C28 is the C13 labeled Bongkrekic acid. Bongkrekic acid is a mitochondrial toxin secreted by the bacteria Pseudomonas cocovenenans. Bongkrekic acid specific ligand for mitochondrial adenine nucleotide translocase (ANT) rather than the electron transport chain. Bongkrekic acid has to cross the mitochondrial inner membrane to produce its inhibitory effect on ADP/ATP transport .
|
-
- HY-B0220S3
-
|
|
Bacterial
|
Infection
|
|
Erythromycin- 13C2 is a macrolide antibiotic that can be used to treat respiratory infections, skin infections, and chlamydia infections .
|
-
- HY-B1422S
-
|
Aminacrine-13C6
|
Bacterial
HIV
Isotope-Labeled Compounds
|
Infection
|
|
9-Aminoacridine-13C6 is the 13C-labeled 9-Aminoacridine(HY-B1422). 9-Aminoacridine, a fluorescent probe, acts as an indicator of pH for quantitative determination of transmembrane pH gradients (inside acidic). 9-Aminoacridine is an antimicrobial. 9-Aminoacridine exerts its antimicrobial activity by interacting with specific bacterial DNA and disrupting the proton motive force in K. pneumoniae. 9-Aminoacridine is a HIV-1 inhibitor and inhibits HIV LTR transcription highly dependent on the presence and location of the amino moiety. 9-Aminoacridine inhibits virus replication in HIV-1 infected cell lines. 9-Aminoacridine is used as a Rifampin (RIF; HY-B0272) adjuvant for the multidrug-resistant K. pneumoniae infections .
|
-
- HY-143704S
-
|
Mesalamine-13C6 hydrochloride; 5-ASA-13C6 hydrochloride; Mesalazine-13C6 hydrochloride
|
PPAR
NF-κB
PAK
|
Metabolic Disease
|
|
5-Aminosalicylic acid-13C6 hydrochloride?(Mesalamine-13C6 hydrochloride; 5-ASA-13C6 hydrochloride; Mesalazine-13C6 hydrochloride) is the 13C labeled 5-Aminosalicylic Acidhydrochloride. 5-Aminosalicylic acid-13C6 hydrochloride?acts as a PPARγ agonist, and also inhibits p21-activated kinase 1 (PAK1) and NF-κB .
|
-
- HY-W010042S3
-
-
- HY-N0136S1
-
|
(±)-Dihydroquercetin-13C3
|
Autophagy
Tyrosinase
|
Inflammation/Immunology
|
|
(±)-Taxifolin-13C3 ((±)-Dihydroquercetin-13C3) is a derivative of (±)-Taxifolin, labeled with 13C3. (±)-Taxifolin is the racemate of Taxifolin. Taxifolin exhibits important anti-tyrosinase activity. Taxifolin exhibits significant inhibitory activity against collagenase with an IC50 value of 193.3 μM . Taxifolin is an important natural compound with antifibrotic activity. Taxifolin is a free radical scavenger with antioxidant capacity .
|
-
- HY-W777681
-
-
- HY-B0149S3
-
|
Cyclocapron-13C2,15N
|
Isotope-Labeled Compounds
|
Inflammation/Immunology
|
|
Tranexamic acid- 13C2, 15N (Cyclocapron- 13C2, 15N) is the 13C2 and 15N labeled Tranexamic acid. Tranexamic acid is an antifibrinolytic agent that alleviates liver damage and fibrosis in mouse models of chronic bile duct injury .
|
-
- HY-126050S
-
|
Pantetheine-15N
|
Isotope-Labeled Compounds
|
Others
|
|
(R)-Pantetheine- 15N (Pantetheine- 15N) is the 15N labeled (R)-Pantetheine (HY-126050). (R)-Pantetheine is the biosynthetic precursor to CoA .
|
-
- HY-B1028S
-
|
D-Pantethine-15N2; LBF disulfide-15N2
|
Isotope-Labeled Compounds
|
Neurological Disease
Metabolic Disease
Inflammation/Immunology
Endocrinology
Cancer
|
|
Pantethine- 15N2 is the 15N2 labeled Pantethine. Pantethine is an orally active lipid-lowering agent. Pantethine has anti-tumor, anti-inflammatory and anti-SARS-COV virus activities. Pantethine is also a neuroprotective agent. Pantethine can be used in the study of Alzheimer's disease, Parkinson's disease, major depression, systemic sclerosis and pantothenate kinase-related neurodegeneration .
|
-
- HY-N0086S3
-
|
6-Methyladenosine-13C3; N-Methyladenosine-13C3
|
Isotope-Labeled Compounds
Influenza Virus
Endogenous Metabolite
|
Infection
|
|
N6-Methyladenosine- 13C3 (6-Methyladenosine- 13C3) is 13C-labeled N6-Methyladenosine (HY-N0086). N6-Methyladenosine is the most prevalent internal (non-cap) modification present in the messenger RNA (mRNA) of all higher eukaryotes. N6-Methyladenosine can modifies viral RNAs and has antiviral activities .
|
-
- HY-W762012S
-
|
OCDD-13C12
|
Isotope-Labeled Compounds
|
Others
|
|
Octachlorodibenzo-p-dioxin- 13C12 is Octachlorodibenzo-p-dioxin- 13 C-labeled octachlorodibenzo-p-dioxin- 13C. Octachlorodibenzo-p-dioxin is a widespread environmental pollutant .
|
-
- HY-N0097S4
-
|
DL-Guanosine-13C10; Vernine-13C10
|
Isotope-Labeled Compounds
Endogenous Metabolite
HSV
|
Infection
|
|
Guanosine- 13C10 is the 13C labeled Guanosine (HY-N0097). Guanosine is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. Guanosine possesses anti-HSV activity .
|
-
- HY-W751165
-
-
- HY-N0092S3
-
-
- HY-B0158S7
-
|
Cytosine β-D-riboside-13C9; Cytosine-1-β-D-ribofuranoside-13C9
|
Nucleoside Antimetabolite/Analog
Endogenous Metabolite
Isotope-Labeled Compounds
|
Neurological Disease
|
|
Cytidine- 13C9 (Cytosine β-D-riboside- 13C9; Cytosine-1-β-D-ribofuranoside- 13C9) is 13C labeled Cytidine (HY-B0158). Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catecholamine synthesis, and mitochondrial function .
|
-
- HY-B0183S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
Ellagic acid- 13C12 is 13 C-labeled Ellagic acid (HY-B0183). Ellagic acid is a natural antioxidant and acts as a potent and ATP-competitive inhibitor of CK2 and SHP2, with an IC50 of 40 nM and a Ki of 20 nM .
|
-
- HY-N0097S6
-
|
DL-Guanosine-13C10,15N5; Vernine-13C10,15N5
|
HSV
Isotope-Labeled Compounds
|
Infection
|
|
Guanosine- 13C10, 15N5 is the 13C and 15N labeled Guanosine (HY-N0097). Guanosine (DL-Guanosine) is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. Guanosine possesses anti-HSV activity .
|
-
- HY-15407S3
-
|
AHU-377-13C4
|
Isotope-Labeled Compounds
Neprilysin
|
Infection
|
|
Sacubitril-13C4 (AHU-377-13C4) is a 13C-labeled version of Sacubitril (HY-15407). Sacubitril is an orally active inhibitor of neprilysin NEP (IC50=5 nM). Sacubitril is used in research on heart failure, hypertension and COVID-19 .
|
-
- HY-B2221S4
-
-
- HY-B2221S5
-
|
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Others
|
|
U- 13C Cellulose from broccoli is the 13C labeled Cellulose (HY-B2221). Cellulose is a natural high molecular weight polysaccharide found in many plants and organisms. It is widely used in manufacturing industries, such as in paper making, textiles, food and medicine, etc. As a renewable resource, Cellulose is biodegradable and sustainable, and can also be used to manufacture chemicals such as Cellulose Esters, Cellulose Acetate and Cellulose Nitrate. In addition, Cellulose is often used as a food additive to increase the stability and quality of food .
|
-
- HY-158034S
-
-
- HY-B2221S1
-
|
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Others
|
|
U- 13C Cellulose from chicory is the 13C labeled Cellulose (HY-B2221). Cellulose (Pectin glycosidase) is a natural high molecular weight polysaccharide found in many plants and organisms. It is widely used in manufacturing industries, such as in paper making, textiles, food and medicine, etc. As a renewable resource, Cellulose is biodegradable and sustainable, and can also be used to manufacture chemicals such as Cellulose Esters, Cellulose Acetate and Cellulose Nitrate. In addition, Cellulose is often used as a food additive to increase the stability and quality of food .
|
-
- HY-B2221S
-
|
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Others
|
|
U- 13C Cellulose high DP from potato is the 13C labeled Cellulose (HY-B2221). Cellulose (Pectin glycosidase) is a natural high molecular weight polysaccharide found in many plants and organisms. It is widely used in manufacturing industries, such as in paper making, textiles, food and medicine, etc. As a renewable resource, Cellulose is biodegradable and sustainable, and can also be used to manufacture chemicals such as Cellulose Esters, Cellulose Acetate and Cellulose Nitrate. In addition, Cellulose is often used as a food additive to increase the stability and quality of food .
|
-
- HY-B2221S3
-
|
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Others
|
|
U- 13C Cellulose high DP from maize is the 13C labeled Cellulose (HY-B2221). Cellulose (Pectin glycosidase) is a natural high molecular weight polysaccharide found in many plants and organisms. It is widely used in manufacturing industries, such as in paper making, textiles, food and medicine, etc. As a renewable resource, Cellulose is biodegradable and sustainable, and can also be used to manufacture chemicals such as Cellulose Esters, Cellulose Acetate and Cellulose Nitrate. In addition, Cellulose is often used as a food additive to increase the stability and quality of food .
|
-
- HY-W653925
-
-
- HY-W718796
-
|
|
Isotope-Labeled Compounds
TMV
|
Cancer
|
|
DL-Serine- 15N is 15N-labeled DL-Serine (HY-Y0507) DL-Serine, a fundamental metabolite, is a mixture of D-Serine and L-Serine. DL-Serine has antiviral activity against the multiplication of tobacco mosaic virus (TMV).
|
-
- HY-23506S
-
-
- HY-N0294S1
-
-
- HY-A0084S1
-
|
Procaine amide-13C2 hydrochloride; SP 100-13C2 hydrochloride
|
Isotope-Labeled Compounds
|
Cancer
|
|
Procainamide- 13C2 hydrochloride is 13C labeled Procainamide. Procainamide hydrochloride is an antiarrhythmic agent used in the study of cardiac arrhythmias.
|
-
- HY-19717S
-
|
S-[(1E)-1,2-Dichloroethenyl]-L-cysteine-13C3,15N
|
Isotope-Labeled Compounds
|
Inflammation/Immunology
|
|
DCVC- 13C3, 15N is 15N and 13C labeled DCVC. DCVC (S-[(1E)-1,2-Dichloroethenyl]-L-cysteine) is a bioactive metabolite of trichloroethylene (TCE). DCVC inhibits pathogen-stimulated pro-inflammatory cytokines IL-1β, IL-8, and TNF-α release from tissue cultures .
|
-
- HY-Y0383S2
-
-
- HY-W017522S6
-
|
|
Isotope-Labeled Compounds
|
Metabolic Disease
|
|
Adipic acid- 13C2 is 13C labeled Adipic acid. Adipic acid is found to be associated with HMG-CoA lyase deficiency, carnitine-acylcarnitine translocase deficiency, malonyl-Coa decarboxylase deficiency, and medium Chain acyl-CoA dehydrogenase deficiency, which are inborn errors of metabolism.
|
-
- HY-W747621
-
-
- HY-W280531S1
-
-
- HY-W768338
-
|
D-(+)-Saccharose-13C
|
Isotope-Labeled Compounds
|
Metabolic Disease
Cancer
|
|
Sucrose- 13C is 13C labeled Sucrose. Sucrose (D-(+)-Saccharose) is a disaccharide which is composed of two monosaccharides, glucose and fructose. Sucrose?can be applied in some animal models, including metabolic disease, obesity,?diet on preference,?and diabetes, et al .
|
-
- HY-W768340
-
|
D-(+)-Saccharose-13C6-1
|
Isotope-Labeled Compounds
|
Metabolic Disease
Cancer
|
|
Sucrose- 13C6-1 is 13C labeled Sucrose. Sucrose (D-(+)-Saccharose) is a disaccharide which is composed of two monosaccharides, glucose and fructose. Sucrose?can be applied in some animal models, including metabolic disease, obesity,?diet on preference,?and diabetes, et al .
|
-
- HY-W067028S
-
|
Aminourea-13C,15N2 hydrochloride; Hydrazinecarboxamide-13C,15N2 hydrochloride
|
Isotope-Labeled Compounds
|
Others
|
|
Semicarbazide- 13C, 15N2 hydrochloride is 15N and 13C labeled Semicarbazide.
|
-
- HY-B0124S1
-
-
- HY-B1511S
-
|
Cyclic adenosine monophosphate-13C5; Adenosine cyclic 3', 5'-monophosphate-13C5; cAMP-13C5
|
Isotope-Labeled Compounds
|
Others
|
|
Cyclic AMP- 13C5 is a deuterated cyclic AMP.
|
-
- HY-N6692S
-
|
|
Endogenous Metabolite
Isotope-Labeled Compounds
|
Inflammation/Immunology
|
|
Diacetoxyscirpenol- 13C19 is 13C labeled 2-Acetylfuran (HY-W015912). 2-Acetylfuran (2-Furyl methyl ketone), an important flavour compound or intermediate in foods, is isolated from essential oils, sweet corn products, fruits and flowers. 2-Acetylfuran also can be formed from glucose and glycine by Maillard reaction. 2-Acetylfuran can be used to synthesis Cefuroxime .
|
-
- HY-N6715S
-
-
- HY-N6725S
-
-
- HY-N6739S
-
-
- HY-N6745S
-
|
|
Na+/K+ ATPase
Apoptosis
Isotope-Labeled Compounds
|
Infection
|
|
Citreoviridin- 13C23 is 13C labeled 2,3-Pentanedione (HY-W012998). 2,3-Pentanedione is a common constituent of synthetic flavorings and is used to impart a butter, strawberry, caramel, fruit, rum, or cheese flavor in beverages, ice cream, candy, baked goods, gelatins, and puddings. 2,3-Pentanedione also occurs naturally as a fermentation product in beer, wine, and yogurt and is releasedduring roasting of coffee beans .
|
-
- HY-W050154S
-
|
|
Parasite
Isotope-Labeled Compounds
|
Infection
|
|
Kojic acid- 13C6 is 13C labeled 2,3-Pentanedione (HY-W012998). 2,3-Pentanedione is a common constituent of synthetic flavorings and is used to impart a butter, strawberry, caramel, fruit, rum, or cheese flavor in beverages, ice cream, candy, baked goods, gelatins, and puddings. 2,3-Pentanedione also occurs naturally as a fermentation product in beer, wine, and yogurt and is releasedduring roasting of coffee beans .
|
-
- HY-A0003S2
-
|
CC-5013-13C5,15N
|
Ligands for E3 Ligase
Apoptosis
Molecular Glues
Isotope-Labeled Compounds
|
Inflammation/Immunology
Cancer
|
|
Lenalidomide- 13C5, 15N is 15N and 13C labeled Lenalidomide (HY-A0003). Lenalidomide (CC-5013), a derivative of Thalidomide, acts as molecular glue. Lenalidomide is an orally active immunomodulator. Lenalidomide (CC-5013) is a ligand of ubiquitin E3 ligase cereblon (CRBN), and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide (CC-5013) specifically inhibits growth of mature B-cell lymphomas, including multiple myeloma, and induces IL-2 release from T cells .
|
-
- HY-Y0921S3
-
|
1,2-(RS)-Propanediol-13C3; 1,2-Propylene glycol-13C3; Propylene glycol-13C3
|
Endogenous Metabolite
Isotope-Labeled Compounds
|
Neurological Disease
|
|
(±)-1,2-Propanediol- 13C3 is 13C labeled (±)-1,2-Propanediol (HY-Y0921). (±)-1, 2-propanediol (1,2-(RS)-Propanediol) is an aliphatic alcohol that is often used as an excipient in many active molecular preparations to increase the solubility and stability of the active molecule. (±)-1, 2-propanediol can affect the neurobehavior of zebrafish .
|
-
- HY-14164S1
-
-
- HY-B0375S1
-
|
MD-805-13C6 hydrochloride; MCI-9038-13C6 hydrochloride; Argipidine-13C6 hydrochloride
|
Thrombin
Isotope-Labeled Compounds
|
Cardiovascular Disease
|
|
Argatroban- 13C6 hydrochloride is 13C labeled Argatroban (HY-B0375). Argatroban (MD-805) is a direct, selective thrombin inhibitor.
|
-
- HY-19657S
-
-
- HY-109120S1
-
-
- HY-113420S2
-
|
|
Endogenous Metabolite
Isotope-Labeled Compounds
|
Metabolic Disease
|
|
11-Dehydro-thromboxane B2- 13C5 is 13C labeled 11-Dehydro-thromboxane B2 (HY-113420). 11-Dehydro-thromboxane B2 is a platelet hemagglutinin. Thromboxane inhibition was assessed by urinary excretion levels of 11-Dehydro-thromboxane B2. 11-Dehydro-thromboxane B2 can be used in the study of atherosclerotic thrombosis .
|
-
- HY-10984S3
-
-
- HY-17416AS1
-
|
|
Adrenergic Receptor
Isotope-Labeled Compounds
|
Neurological Disease
Endocrinology
|
|
Guanfacine- 15N3, 13C2 is 15N and 13C labeled Guanfacine (HY-17416A). Guanfacine is an orally active noradrenergic α2A agonist and has high selective for the α2A receptor subtype. Guanfacine has effects in producing hypotension and sedation. Guanfacine can be used for the research of a variety of prefrontal cortex (PFC) cognitive disorders, including tourette's syndrome and attention deficit hyperactivity disorder (ADHD) .
|
-
- HY-154773S
-
-
- HY-B0271S1
-
|
Pyrazinecarboxamide-13C,15N; Pyrazinoic acid amide-13C,15N
|
Autophagy
Antibiotic
Bacterial
Isotope-Labeled Compounds
|
Infection
|
|
Pyrazinamide- 13C, 15N is 15N and 13C labeled Pyrazinamide (HY-B0271). Pyrazinamide (Pyrazinecarboxamide; Pyrazinoic acid amide) is a potent and orally active antitubercular antibiotic. Pyrazinamide is a proagent that is converted to the active form pyrazinoic acid (POA) by PZase/nicotinamidase encoded by the pncA gene in M. tuberculosis.
|
-
- HY-154814S
-
-
- HY-12956S2
-
-
- HY-B0347S3
-
|
|
Calcium Channel
Caspase
Reactive Oxygen Species
Apoptosis
Isotope-Labeled Compounds
|
Cardiovascular Disease
|
|
Lacidipine- 13C4 is 13C labeled Lacidipine (HY-B0347). Lacidipine is an orally active and highly selective L-type calcium channel blocker that acts on smooth muscle calcium channels, primarily dilates peripheral arteries, reduces peripheral resistance, and has long-lasting anti-hypertensive activity. Lacidipine protects HKCs from apoptosis induced by ATP depletion and recovery by modulating the caspase-3 pathway. Lacidipine can be used in studies of hypertension, atherosclerosis and acute kidney injury (AKI) .
|
-
- HY-B0111RS
-
|
Dihydrospirorenone-13C3
|
Isotope-Labeled Compounds
|
Endocrinology
|
|
Drospirenone- 13C3 is 13C labeled Drospirenone. Drospirenone (Dihydrospirorenone) is a synthetic progesterone that is an analog of Spironolactone .
|
-
- HY-B0139AS
-
|
5-Fluorocytosine-15N3 hydrochloride; NSC 103805-15N3 hydrochloride; Ro 2-9915-15N3 hydrochloride
|
Isotope-Labeled Compounds
|
Others
|
|
Flucytosine- 15N3 hydrochloride is 15N labeled Flucytosine.
|
-
- HY-154746S
-
-
- HY-113209S2
-
|
|
Endogenous Metabolite
Isotope-Labeled Compounds
|
Others
|
|
8-Isoprostaglandin F2α- 13C5 is 13C labeled 8-Isoprostaglandin F2α (HY-113209). 8-Isoprostaglandin F2α is an isoprostane produced by the non-enzymatic peroxidation of arachidonic acid in membrane phospholipids. 8-Isoprostaglandin F2α is present in human plasma in two distinct forms - esterified in phospholipids and as the free acid. 8-Isoprostaglandin F2α is a weak TP receptor agonist in vascular smooth muscle.
|
-
- HY-W585890S
-
-
![Benzo[pqr]tetraphen-3-ol-13C6](//file.medchemexpress.eu/product_pic/hy-w585890s.gif)
- HY-100043S
-
-
- HY-118560S
-
|
NSC 6598-13C2; Herbaflorat-13C2; Greenyl acetate-13C2; Verdyl acetate-13C2
|
Isotope-Labeled Compounds
|
Others
|
|
Tricyclodecenyl acetate- 13C2 is 13C labeled 2-Acetylthiazole.
|
-
- HY-150194S
-
-
- HY-156326S
-
-
- HY-156326S1
-
-
- HY-50719S1
-
-
- HY-B1290S3
-
-
- HY-N0368S1
-
|
|
Apoptosis
Endogenous Metabolite
iGluR
Bacterial
Isotope-Labeled Compounds
|
Cancer
|
|
Linalool- 13C3 is 13C labeled α-Hexylcinnamaldehyde (HY-W014118). α-Hexylcinnamaldehyde, a compound derived from Cinnamaldehyde. α-Hexylcinnamaldehyde has the potential antimutagenic and chemosensitizing properties. α-Hexylcinnamaldehyde is widely used as an ingredient in many personal care, and as an additive in food and the pharmaceutical industry .
|
-
- HY-N0803S1
-
|
β-Myrcene-13C3
|
NF-κB
Isotope-Labeled Compounds
|
Others
|
|
Myrcene- 13C3 is 13C labeled trans-2-Decenal (HY-W015551). trans-2-Decenal is an important raw material and intermediate used in organic synthesis, medicine, pesticides and dyes.
|
-
- HY-N10004S
-
-
- HY-N7125S
-
|
|
Bacterial
Isotope-Labeled Compounds
|
Others
|
|
Cinnamyl acetate- 13C2 is 13C labeled Nerolidol (HY-N1944). Nerolidol has multiple natural membrane activities, possesses anti-cancer, anti-inflammatory, antibacterial and anti-insect activity. Nerolidol Suppresses parasitic activity, suppresses bloodsucking diseases, bloodworm diseases, and other diseases. Nerolidol can protect the cells from lipid and protein properties, damage to DNA, and protect the cells from damage .
|
-
- HY-N9484S
-
|
|
Drug Metabolite
Isotope-Labeled Compounds
|
Others
|
|
Menthofuran- 13C2 is 13C labeled Menthol (HY-N1369). Menthol is an analgesic and TRPM8 modulator. TRPM8 is a cold temperature sensing ion channel, and Menthol can regulate TRPM8 to exert analgesic and anti-irritation mechanisms. Menthol stimulates cold receptors and produces a cooling sensation by inhibiting Ca ++ currents in neuronal cell membranes. Menthol also improves oral nicotine rejection in mice .
|
-
- HY-W001942S2
-
-
- HY-W010392S1
-
-
- HY-W010489S1
-
-
- HY-W012578S1
-
-
- HY-W012932S
-
-
- HY-W012980S4
-
|
|
Endogenous Metabolite
Isotope-Labeled Compounds
|
Metabolic Disease
|
|
Isovaleric acid- 13C2 is 13C labeled Gamma-decalactone (HY-N7105). Gamma-decalactone, γ-decalactone is used as an essential food additive with a ruity peach flavor . Ricinoleic acid (12-hydroxy-octadec-9-enoic acid) is used as the substrate in most production processes of γ-decalactone .
|
-
- HY-W012998S1
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
2,3-Pentanedione- 13C2 is 13C labeled Furaneol (HY-N7093). Furaneol is mainly isolated from American grape (Vitis labrusca) and its hybrid grape. Furaneol is an important aroma compound in fruits and contribute to the strawberry-like note in some wines .
|
-
- HY-W015307S
-
|
|
Biochemical Assay Reagents
Isotope-Labeled Compounds
|
Others
|
|
4-Ethyloctanoic acid- 13C2 is 13C labeled Cuminaldehyde (HY-Y0790). Cuminaldehyde is the major component of Cuminum cyminum, a natural aldehyde with inhibitory effect on alpha-synuclein fibrillation and cytotoxicity. Cuminaldehyde shows anticancer activity .
|
-
- HY-W015604S
-
-
- HY-W020678S
-
-
- HY-W102356S1
-
-
- HY-W127515S
-
-
- HY-W156840S
-
|
ethanone, 1-(1,2,3,4,5,6,7,8-octahydro-2,3,8,8-tetramethyl-2-naphthalenyl)-13C3
|
Isotope-Labeled Compounds
|
Others
|
|
OTNE- 13C3 is 13C labeled 2-methoxy-4-propylphenol.
|
-
- HY-W343292S
-
-
- HY-W585933S
-
-
- HY-W585934S
-
-
- HY-W721295S
-
-
- HY-W738582S
-
-
- HY-W768581
-
-
- HY-W772341
-
-
- HY-W779534
-
-
- HY-W779542
-
-
- HY-W793608S
-
-
- HY-Y0045S
-
|
1-(1,3-Thiazol-2-yl)ethanone-13C2; 1-(Thiazol-2-yl)ethanone-13C2; Methyl 2-thiazolyl ketone-13C2
|
Isotope-Labeled Compounds
|
Others
|
|
2-Acetylthiazole- 13C2 is 13C labeled Fructose-phenylalanine.
|
-
- HY-W749251
-
|
5-ALA-13C2,15N hydrochloride; δ-Aminolevulinic acid-13C2,15N hydrochloride; 5-Amino-4-oxopentanoic acid-13C2,15N hydrochloride
|
Endogenous Metabolite
Isotope-Labeled Compounds
|
Others
|
|
5-Aminolevulinic acid- 13C2, 15N (5-ALA- 13C2, 15N; δ-Aminolevulinic acid- 13C2, 15N) is 13C- and 15N-labeled 5-Aminolevulinic acid (HY-W000450) .
|
-
- HY-W145482S1
-
-
- HY-W778064
-
-
- HY-B0356AS1
-
-
- HY-W779017
-
-
- HY-B0283S1
-
-
- HY-B0084S3
-
-
- HY-W777418
-
-
- HY-B0122SS1
-
-
- HY-W018386S1
-
-
- HY-116021S
-
|
|
Isotope-Labeled Compounds
Parasite
|
Infection
|
|
Buquinolate-13C3 is the 13C3 labeled Buquinolate. Buquinolate is a quinoline derivative, which is developed as a coccidiostat for the prevention of coccidiosis in poultry .
|
-
- HY-114360AS1
-
|
|
Isotope-Labeled Compounds
TNF Receptor
Interleukin Related
|
Inflammation/Immunology
|
|
Taurohyodeoxycholic acid-d4 (sodium) is a deuterated labeled Taurohyodeoxycholic acid (sodium) . Taurohyodeoxycholic acid (THDCA) sodium is the taurine-conjugated form of the secondary bile acid hyodeoxycholic acid. Taurohyodeoxycholic acid can also reduce the activity and expression of myeloperoxidase TNF-α and IL-6, as well as colonic damage in TNBS-induced ulcerative colitis mouse model.
|
-
- HY-141629S1
-
-
- HY-109506S9
-
|
129Y83-13C2
|
Isotope-Labeled Compounds
Endogenous Metabolite
Liposome
|
Others
|
|
DPPC-13C2 is a deuterated labeled DPPC . DPPC (129Y83) is a phosphoglyceride that can be used to prepare lipid monolayers, bilayers, and liposomes. DPPC is the main lipid component of pulmonary surfactant. Dppc-liposome can be effectively used as a delivery vector to induce an immune response against GSL antigen in mice .
|
-
- HY-16637S5
-
|
Vitamin B9-13C6; Vitamin M-13C6
|
Isotope-Labeled Compounds
DNA/RNA Synthesis
Endogenous Metabolite
|
Cancer
|
|
Folic acid-13C6 is a deuterated labeled Folic acid . Folic acid (Vitamin B9) is a orally active essential nutrient from the B complex group of vitamins. Folic acid shows antidepressant-like effect. Folic acid sodium reduces the risk of neonatal neural tube defects. Folic acid can be used to the research of megaloblastic and macrocytic anemias due to folic deficiency .
|
-
- HY-131622S
-
-
- HY-B1804S
-
-
- HY-151997S
-
|
1,2-Olein-3-laurin-13C3; TG(18:1/18:1/12:0)-13C3
|
Isotope-Labeled Compounds
|
Others
|
|
1,2-Dioleoyl-3-lauroyl-rac-glycerol- 13C3 is the 13C-labeled 1,2-Dioleoyl-3-lauroyl-rac-glycerol (HY-165089), 1,2-Dioleoyl-3-lauroyl-rac-glycerol (1,2-Olein-3-laurin) is a triglyceride identified by specific analytical methods in human milk, infant formula, other mammalian milk, and vegetable oils, with specific structural and distribution characteristics.
|
-
- HY-W814363
-
-
- HY-W585905
-
-
- HY-W009326S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
Laurocapram-15N is a deuterated labeled Laurocapram . Laurocapram is a absorption enhancer and has been one of the most effective for substances of both lipophilic and hydrophilic nature .
|
-
- HY-76082S1
-
|
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Others
|
|
L-Pyroglutamic acid-13C5 is a deuterated labeled L-Pyroglutamic acid . L-Pyroglutamic acid is the levo-isomer of Pyroglutamic acid. L-Pyroglutamic acid is the biologically active enantiomer in humans. Pyroglutamic acid is an intermediate in glutathione metabolism.
|
-
- HY-W654190
-
-
- HY-W654241
-
-
- HY-66008S2
-
|
N-Acetyl-5-aminosalicylic acid-13C6; N-Acetyl-ASA-13C6
|
Isotope-Labeled Compounds
Drug Metabolite
|
Inflammation/Immunology
|
|
N-Acetyl mesalazine-13C6 is a deuterated labeled N-Acetyl mesalazine . N-Acetyl mesalazine (N-Acetyl-5-aminosalicylic acid) is the metabolite of 5-Aminosalicylic Acid (HY-15027) with endoscopic activity. N-Acetyl mesalazine can be used for the research of ulcerative colitis .
|
-
- HY-W782153
-
-
- HY-10260S2
-
|
ZD6474-13C6
|
Isotope-Labeled Compounds
VEGFR
Autophagy
Apoptosis
|
Cancer
|
|
Vandetanib-13C6 is a deuterated labeled Vandetanib . Vandetanib (D6474) is a potent, orally active inhibitor of VEGFR2/KDR tyrosine kinase activity (IC50=40 nM). Vandetanib also has activity versus the tyrosine kinase activity of VEGFR3/FLT4 (IC50=110 nM) and EGFR/HER1 (IC50=500 nM) .
|
-
- HY-137222S
-
|
|
COX
|
Inflammation/Immunology
|
|
4',5-Dihydroxy Diclofenac-13C6 is a deuterated derivative of Diclofenac (HY-15036). Diclofenac is a potent COX inhibitor with anti-inflammatory activity .
|
-
- HY-W777526
-
-
- HY-W780150
-
-
- HY-W013186S1
-
-
- HY-B0284S2
-
-
- HY-W777286
-
-
- HY-15284S3
-
|
PCR 4099-13C6
|
Isotope-Labeled Compounds
P2Y Receptor
|
Cardiovascular Disease
|
|
Prasugrel-13C6 is a deuterated labeled Prasugrel . Prasugrel (PCR 4099), a thienopyridine and proagent, inhibits platelet function. Prasugrel is an orally active and potent P2Y12 receptor antagonist, and inhibits ADP-induced platelet aggregation .
|
-
- HY-W013636S4
-
|
Alpha-Ketoglutaric acid-13C2
|
Isotope-Labeled Compounds
Tyrosinase
Endogenous Metabolite
|
Others
|
|
2-Ketoglutaric acid-13C2 is a deuterated labeled 2-Ketoglutaric acid . 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC50=15 mM) .
|
-
- HY-17356S2
-
-
- HY-113128S
-
|
|
Isotope-Labeled Compounds
|
Metabolic Disease
|
|
sn-Glycerol 3-phosphate- 13C3 disodium is the 13C-labeled sn-Glycerol 3-phosphate disodium. sn-Glycerol 3-phosphate disodium is produced by cytosolic glycerol 3-phosphate dehydrogenase pathway through the reduction of dihydroxyacetone phosphate using NADH formed during glycolysis .
|
-
- HY-115705
-
|
Glycerol tri-10(Z)-heptadecenoate; TG(17:1/17:1/17:1); Tri-10(Z)-heptadecenoin
|
Biochemical Assay Reagents
|
Others
|
|
1,2,3-Tri-10(Z)-heptadecenoyl glycerol (TG(17:1/17:1/17:1)) is a biochemical assay reagent, which can be used as an internal standard for the quantification of biological triglyceride .
|
-
- HY-W705777
-
-
- HY-B1252AS
-
|
|
Isotope-Labeled Compounds
|
Infection
|
|
Cefalonium-d4 (hydrate) is the deuterium labeled Cefalonium (hydrate)(HY-B1252A).Cefalonium hydrate is the first-generation β-lactam cephalosporin antibiotic that is widely used to research bovine mastitis caused by Gram-positive bacteria including staphylococci .
|
-
- HY-B0152S7
-
|
6-Aminopurine-15N5 hydrochloride hydrate; Vitamin B4-15N5 hydrochloride hydrate
|
DNA/RNA Synthesis
Isotope-Labeled Compounds
|
Cancer
|
|
Adenine-15N5 hydrochloride hydrate (6-Aminopurine-15N5 hydrochloride hydrate) is the deuterium labeled Adenine (HY-B0152). Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis .
|
-
- HY-15121S1
-
|
L-Glutamic Acid γ-ethyl amide-13C2,15N2; Nγ-Ethyl-L-glutamine-13C2,15N2
|
DNA/RNA Synthesis
|
Others
|
|
L-Theanine-13C2,15N2yes 13C2, 15N2Tagged L-Theanine (HY-15121).
|
-
- HY-152903S
-
-
- HY-118645S1
-
-
- HY-13771S1
-
|
Ursodeoxycholate-13C; Ursodiol-13C; UDCA-13C
|
Isotope-Labeled Compounds
G protein-coupled Bile Acid Receptor 1
FXR
Endogenous Metabolite
|
Cancer
|
|
Ursodeoxycholic acid- 13C is the 13C labeled Ursodeoxycholic acid. Ursodeoxycholic acid (Ursodeoxycholate) is a secondary bile acid issued from the transformation of (cheno)deoxycholic acid by intestinal bacteria, acting as a key regulator of the intestinal barrier integrity and essential for lipid metabolism. Ursodeoxycholic acid acts as signaling molecule, exerting its effects by interacting with bile acid activated receptors, including G-protein coupled bile acid receptor 5 (TGR5, GPCR19) and the farnesoid X receptor (FXR). Ursodeoxycholic acid can be used for the research of a variety of hepatic and gastrointestinal diseases. Orally active[1][2].
|
-
- HY-W779002
-
|
|
Isotope-Labeled Compounds
|
|
|
alpha-D-glucose-13C2-1 is a 13C labeled alpha-D-glucose. alpha-D-glucose is an endogenous metabolite[1].
|
-
- HY-112537S2
-
-
- HY-W750551
-
-
- HY-79128S1
-
-
- HY-W777649
-
-
- HY-W715351S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
1,2,4,5,7,8-Hexachloro naphthalene- 13C10 is 13C labeled 1,2,4,5,7,8-Hexachloronaphthalene .
|
-
- HY-W549233S
-
-
- HY-W748196S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
1,2,3,4,6,7-Hexachloro dibenzo-p-dioxin- 13C12 is 13C labeled 1, 2, 3, 4, 6, 7- Hexachlorodibenzo- p- dioxin .
|
-
- HY-W715365S
-
-
- HY-127035S1
-
-
- HY-W748346
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
2,2′,3,3′,5,5′,6-Heptachloro biphenyl- 13C12 is 13C labeled 2,2',3,3',5,5',6-Heptachloro-1,1'-biphenyl .
|
-
- HY-23805S
-
-
- HY-W327895S
-
-
- HY-130462S2
-
|
POPC-13C16; 2-oleoyl-1-palmitoyl-sn-glycero-3-phosphocholine-13C16
|
Isotope-Labeled Compounds
Liposome
|
Others
|
|
1-Palmitoyl-2-oleoyl-sn-glycero-3-PC- 13C16 (POPC- 13C16) is 13C labeled 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (POPC), a phospholipid, is a major component of biological membranes. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC is used for the preparation of liposomes and studying the properties of lipid bilayers .
|
-
- HY-W718525S
-
-
- HY-W751145
-
-
- HY-W750297
-
|
4,4'-DDD-13C12; p,p'-Dichlorodiphenyl dichloroethane-13C12
|
Isotope-Labeled Compounds
Drug Metabolite
|
Others
|
|
p,p'-DDD- 13C12 is 13C labeled p,p'-DDD. p,p'-DDD is a major metabolite of p,p'-DDT. p,p'-DDD occurs in the feces and livers of rats, that are given p,p'-DDT by stomach tube, but not of rats injected intraperitoneally with p,p'-DDT .
|
-
- HY-W749374
-
-
- HY-W716411S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
1,2,3,4,5-Pentabromo-6-(2,3-dibromophenoxy)benzene- 13C12 is 13C labeled 1,2,3,4,5-Pentabromo-6-(2,3-dibromophenoxy)benzene .
|
-
- HY-W748312
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
1, 2, 3, 4, 7, 8, 9-Heptachloro-dibenzofuran- 13C12 is 13C labeled 1,2,3,4,7,8,9-Heptachlorodibenzo[b,d]furan .
|
-
- HY-W748319
-
-
- HY-W748320
-
|
2,2',3,3',4,4',5,5'-Octachlorobiphenyl-13C12
|
Isotope-Labeled Compounds
|
Others
|
|
2,2',3,3',4,5,5',6,6'-Nonachloro-1,1'-biphenyl- 13C12 is 13C labeled 2,2',3,3',4,5,5',6,6'-Nonachloro-1,1'-biphenyl .
|
-
- HY-W748321
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
2,2',3,4',5,6,6'-heptachloro-1,1'-biphenyl- 13C12 is 13C labeled 2,2',3,4',5,6,6'-Heptachloro-1,1'-biphenyl .
|
-
- HY-W748322
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
1, 2, 3, 4, 7, 8- Hexachloro-dibenzofuran- 13C12 is 13C labeled 1,2,3,4,7,8-Hexachlorodibenzofuran .
|
-
- HY-165124S
-
|
|
Isotope-Labeled Compounds
Biochemical Assay Reagents
|
Others
|
|
1,2,3,4,6,7,8-Heptachlorodibenz- 13C12 is 13C labeled 1,2,3,4,6,7,8-Heptachlorodibenz. 1,2,3,4,6,7,8-Heptachlorodibenz 是一种生化试剂。 .
|
-
- HY-W748327
-
-
- HY-W748343
-
|
2,2',5,5'-Tétrachlorobiphényl-13C12
|
Isotope-Labeled Compounds
|
Others
|
|
2,2',5,5'-Tetrachloro-1,1'-biphenyl- 13C12 is 13C labeled 2,2',5,5'-Tetrachloro-1,1'-biphenyl .
|
-
- HY-W748345
-
|
2,3',4,4',5,5'-Hexachlorobiphenyl-13C12
|
Isotope-Labeled Compounds
|
Others
|
|
2,3',4,4',5,5'-Hexachloro-1,1'-biphenyl- 13C12 is 13C labeled 2,3',4,4',5,5'-Hexachloro-1,1'-biphenyl .
|
-
- HY-W748350
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
2,2',3,3',4,4',5,5',6-Nonachloro-1,1'-biphenyl- 13C12 is 13C labeled 2,2',3,3',4,4',5,5',6-Nonachloro-1,1'-biphenyl .
|
-
- HY-W715357S
-
-
- HY-166906S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
cis-Nonachlor- 13C10 is 13C labeled (1R,2S,3S,3aR,4R,7R,7aS)-1,2,3,4,5,6,7,8,8-Nonachloro-2,3,3a,4,7,7a-hexahydro-1H-4,7-methanoindene .
|
-
- HY-W748290
-
|
3,4,4',5-Tetrachlorobiphenyl-13C12
|
Isotope-Labeled Compounds
|
Others
|
|
3,4,4',5-Tetrachloro-1,1'-biphenyl- 13C12 is 13C labeled 3,4,4',5-Tetrachloro-1,1'-biphenyl .
|
-
- HY-W748204
-
|
|
Isotope-Labeled Compounds
Biochemical Assay Reagents
|
Others
|
|
1,2,3,7,8-Pentachloro dibenzo-p-dioxin- 13C12 is 13C labeled 1,2,3,7,8-Pentachlorodibenzo-p-dioxin. 1,2,3,7,8-Pentachlorodibenzo-p-dioxin is a biochemical reagent .
|
-
- HY-W747639
-
|
|
Isotope-Labeled Compounds
Biochemical Assay Reagents
|
Others
|
|
Glycidyl Stearate- 13C3 is 13C labeled Glycidyl stearate. Oxiran-2-ylmethyl stearate is a compound belonging to the class of esters. It contains reactive oxirane or epoxy groups that give the molecule its unique properties. Oxiran-2-ylmethyl stearate is derived from stearic acid and epichlorohydrin, which are naturally occurring substances. Glycidyl stearate is commonly used in various industrial applications such as the production of coatings, adhesives and surfactants. It can also be used as a crosslinking agent in the manufacture of polymers and resins .
|
-
- HY-W747491
-
|
|
Isotope-Labeled Compounds
Antibiotic
Apoptosis
Bacterial
Fungal
|
Cancer
|
|
Triclosan- 13C12 is 13C labeled Triclosan. Triclosan is a broad-spectrum antibacterial agent that inhibits bacterial fatty acid synthesis at the enoyl-acyl carrier protein reductase (FabI) step. Triclosan inhibits E. coli enoyl-acyl carrier protein reductase (FabI) and FabI containing a glycine-to-valine substitution at position 93 (FabIG93V) with IC50s of 2 μM and 10 μM, respectively. Triclosan causes apoptotic effect in cultured rat neural stem cells (NSC). Triclosan exacerbates colitis and colitis-associated colorectal tumorigenesis in animal models .
|
-
- HY-W762019S
-
|
1,2,3,4,7,8-HxCDD-13C12
|
Isotope-Labeled Compounds
|
Others
|
|
1,2,3,4,7,8-Hexachloro dibenzo-p-dioxin- 13C12 (1,2,3,4,7,8-HxCDD- 13C12) is 13C labeled 1,2,3,4,7,8-Hexachlorodibenzo-p-dioxin .
|
-
- HY-13690S3
-
|
2,4′-DDD-13C12; o,p'-DDD-13C12
|
Isotope-Labeled Compounds
Apoptosis
|
Cancer
|
|
Mitotane- 13C12 (2,4′-DDD- 13C12) is 13C labeled Mitotane. Mitotane (2,4′-DDD), an isomer of DDD and derivative of dichlorodiphenyltrichloroethane (DDT), is an antineoplastic agent, can be used to research adrenocortical carcinoma. Mitotane exert its adrenocorticolytic effect at least in part through lipotoxicity induced by intracellular free cholesterol (FC) accumulation. Mitotane can have direct pituitary effects on corticotroph cells. Mitotane can induce CYP3A4 gene expression via steroid and xenobiotic receptor (SXR) activation, and has agent-agent interactions .
|
-
- HY-W140740S
-
-
- HY-W715180S
-
-
- HY-W715187S
-
-
- HY-109590S3
-
|
Immunocytophyt-13C4
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Cardiovascular Disease
Inflammation/Immunology
|
|
Arachidonic acid- 13C4 (Immunocytophyt- 13C4) is 13C labeled Arachidonic acid. Arachidonic acid (Immunocytophyt) is a polyunsaturated omega-6 fatty acid and a major constituent of biomembranes. Arachidonic acid also acts as the substrate for various lipid mediators, such as prostaglandins (PGs). Arachidonic acid improves cognitive response and cardiovascular function .
|
-
- HY-W011297S2
-
|
Arachidonic acid methyl ester-13C4
|
Isotope-Labeled Compounds
Others
|
Metabolic Disease
|
|
Methyl arachidonate- 13C4 (Arachidonic acid methyl ester- 13C4) is 13C labeled Methyl arachidonate. Methyl arachidonate (Arachidonic acid methyl ester) is a fatty acid methyl ester resulting from the formal condensation of the carboxy group of arachidonic acid with methanol. Methyl arachidonate has activity of human blood serum metabolite .
|
-
- HY-W653853
-
-
- HY-W653916
-
|
8-Oxo-2-Deoxyguanosine-13C,15N2
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Cancer
|
|
8-Hydroxy-2'-deoxyguanosine- 13C, 15N2 is 13C and 15N labeled 8-Hydroxy-2'-deoxyguanosine. 8-Hydroxy-2'-deoxyguanosine is a critical biomarker of oxidative stress and carcinogenesis .
|
-
- HY-W653970
-
-
- HY-W654000
-
|
Guanosine 3',5'-cyclic-13C,15N2 monophosphate
|
Isotope-Labeled Compounds
STING
Endogenous Metabolite
|
Inflammation/Immunology
|
|
Cyclic GMP- 13C, 15N2 is 13C and 15N labeled Cyclic GMP. Cyclic GMP (cGAMP) is an endogenous second messenger that triggers interferon production in response to cytoplasmic DNA. Cyclic GMP activates the stimulator of interferon genes (STING), activating a signaling cascade that leads to the production of type I interferons and other immune mediators .
|
-
- HY-W654002
-
|
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Others
|
|
(3R)-3-Hydroxybutyric acid-1- 13C is 13C labeled (R)-3-Hydroxybutanoic acid. (R)-3-Hydroxybutanoic acid is a metabolite, and converted from acetoacetic acid catalyzed by 3-hydroxybutyrate dehydrogenase. (R)-3-Hydroxybutanoic acid has applications as a nutrition source and as a precursor for vitamins, antibiotics and pheromones .
|
-
- HY-W654004
-
-
- HY-W654080
-
|
α,α'-Bis(4-hydroxyphenyl)-1,4-diisopropylbenzene-13C4
|
Isotope-Labeled Compounds
|
Others
|
|
Bisphenol P- 13C4 is 13C labeled α,α'-Bis(4-hydroxyphenyl)-1,4-diisopropylbenzene .
|
-
- HY-W654082
-
-
- HY-W654098
-
|
|
Isotope-Labeled Compounds
Antibiotic
Bacterial
|
Inflammation/Immunology
|
|
Cefazolin- 13C2, 15N (sodium) is 13C and 15N labeled Cefazolin (sodium). Cefazolin sodium is a first-generation cephalosporin antibiotic and can be used in varieties of bacterial infections research . Cefazolin sodium has anti-inflammatory effect and can attenuate post-operative cognitive dysfunction (POCD).
|
-
- HY-W654127
-
-
- HY-W654136
-
|
Deoxycytidine-13C; Cytosine deoxyriboside-13C; Deoxyribose cytidine-13C
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Cancer
|
|
2'-Deoxycytidine-2'- 13C is 13C labeled 2'-Deoxycytidine. 2'-Deoxycytidine, a deoxyribonucleoside, can inhibit biological effects of Bromodeoxyuridine (Brdu). 2'-Deoxycytidine is essential for the synthesis of nucleic acids, that can be used for the research of cancer .
|
-
- HY-W654156
-
|
|
Isotope-Labeled Compounds
Parasite
Antibiotic
|
Infection
|
|
Diclazuril- 13C3, 15N 2 is 13C and 15N labeled Diclazuril. Diclazuril (R-64433), a benzeneacetonitrile derivative, is a potent and orally active anticoccidial agent. Diclazuril can be used for the research of certain infectious and parasitic diseases, including coccidiosis, acute toxoplasmosis, equine protozoal pyoencephalitis (EPM) et.al .
|
-
- HY-W654191
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
Fipronil detrifluoromethylsulfinyl- 13C2, 15N2 is 13C and 15N labeled 5-Amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-1H-pyrazole-3-carbonitrile .
|
-
- HY-W617979S
-
-
- HY-W777702
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
2,2',3,4',5,5',6-Heptachloro-4-biphenylol- 13C12 is 13C labeled 2,2',3,4',5,5',6-Heptachloro-[1,1'-biphenyl]-4-ol .
|
-
- HY-W552229S
-
-
- HY-W517076S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
1,2,3,6,7,8-Hexachloro dibenzo-p-dioxin- 13C12 is 13C labeled 1,2,3,6,7,8-Hexachlorodibenzo[b,e][1,4]dioxine .
|
-
- HY-W017086S2
-
-
![Dibenzo[b,d]furan-13C12](//file.medchemexpress.eu/product_pic/hy-w017086s2.gif)
- HY-166917S
-
-
- HY-W710384S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
1,2,3,4,5,6,7-Heptachloro naphthalene- 13C10 is 13C labeled 1,2,3,4,5,6,7-Heptachloronaphthalene .
|
-
- HY-166896S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
2,3,3',4',5,5'-Hexachloro-1,1'-biphenyl- 13C12 is 13C labeled 2,3,3',4',5,5'-Hexachloro-1,1'-biphenyl .
|
-
- HY-W714574S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
2,2′,3,3′,4,4′,5-Heptachloro biphenyl- 13C12 is 13C labeled 2,2',3,3',4,4',5-Heptachloro-1,1'-biphenyl .
|
-
- HY-W774917S
-
-
- HY-166898S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
trans Nonachlor- 13C10 is 13C labeled (1R,2R,3S,3aR,4R,7R,7aS)-1,2,3,4,5,6,7,8,8-Nonachloro-2,3,3a,4,7,7a-hexahydro-1H-4,7-methanoindene .
|
-
- HY-W718588S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
2,2',3,3',5,5'-Hexachlorobiphenyl- 13C12 is 13C labeled 2,2',3,3',5,5'-Hexachloro-1,1'-biphenyl .
|
-
- HY-W152813S
-
-
- HY-166908S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
2,2',3,3',4,4',5,6,6'-Nonabromo diphenyl ether- 13C12 is 13C labeled 1,2,3,4,5-Pentabromo-6-(2,3,4,6-tetrabromophenoxy)benzene .
|
-
- HY-W092778S
-
-
- HY-W013061S11
-
-
- HY-W715121S
-
-
- HY-W718518S
-
-
- HY-W718532S
-
-
- HY-166928S
-
-
- HY-W715184S
-
-
- HY-W708160S
-
-
- HY-76595S1
-
-
- HY-W715361S
-
-
- HY-W354105S
-
-
- HY-W718472S
-
-
- HY-W673588S
-
-
- HY-W715198S
-
-
- HY-B1805S1
-
|
3,4,4'-Trichlorocarbanilide-13C13
|
Isotope-Labeled Compounds
Bacterial
|
Infection
|
|
Triclocarban- 13C13 (3,4,4'-Trichlorocarbanilide- 13C13) is 13C labeled Triclocarban. Triclocarban (3,4,4′-Trichlorocarbanilide), a broad spectrum antibacterial compound, is widely used in a broad range of applications such as the production of soaps, skin creams, toothpastes and deodorants. Triclocarban is a potential endocrine-disrupting chemical with the capacity to modulate androgen and estrogen activities as well as other hormone-mediated biological processes .
|
-
- HY-W718614S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
2,3,3′,4,5,5′-Hexachloro biphenyl- 13C12 is 13C labeled 2,3,3',4,5,5'-Hexachloro-1,1'-biphenyl .
|
-
- HY-W715199S
-
-
- HY-W703429S
-
-
- HY-W715311S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
2,2',3,3',4',5,5'-Heptachloro-4-biphenylol- 13C12 is 13C labeled 2,2',3,3',4',5,5'-Heptachloro-[1,1'-biphenyl]-4-ol .
|
-
- HY-166956S
-
-
- HY-W587423S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
2,2′,3,3′,4,4′,5,5′,6-Nonabromo diphenyl ether- 13C12 is 13C labeled 2,2′,3,3′,4,4′,5,5′,6-Nonabromodiphenyl ether .
|
-
- HY-W094748S1
-
-
- HY-W013058S
-
-
- HY-150012S1
-
-
- HY-W779015
-
-
- HY-119649S
-
|
IKI220-15N18O
|
Isotope-Labeled Compounds
Parasite
|
Infection
|
|
Flonicamid- 15N,18O (IKI220- 15N,18O) is 15N labeled Flonicamid. Flonicamid (IKI220) is a novel systemic insecticide with selective activity against hemipterous pests. The main insecticidal mechanism of flonicamid is starvation based on the inhibition of stylet penetration to plant tissues .
|
-
- HY-165696S1
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
2,4-Dicarbamoyl-3,5,6-trichlorobenzenesulfonate (sodium)- 15N2 is 15N labeled 2,4-Dicarbamoyl-3,5,6-trichlorobenzenesulfonate (sodium) .
|
-
- HY-166963S
-
-
- HY-152040S
-
|
3-(Acetyl-13C2)-5-((S)-sec-butyl)-4-hydroxy-1,5-dihydro-2H-pyrrol-2-one
|
Isotope-Labeled Compounds
|
Others
|
|
Tenuazonic acid-(acetyl- 13C2) (mixture of diastereomers) in methanol (3-(Acetyl- 13C2)-5-((S)-sec-butyl)-4-hydroxy-1,5-dihydro-2H-pyrrol-2-one) is 13C labeled Tenuazonic acid-(acetyl) (mixture of diastereomers) in methanol .
|
-
- HY-W018386AS
-
-
- HY-166957S
-
-
- HY-W654373S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
4-((Hydrazinyl)methyl)benzene-1,2,3-triol- 15N2 (oxalate) is 15N labeled 2,3,4-Trihydroxybenzylhydrazine Oxalic Acid Salt .
|
-
- HY-165686
-
|
N-(Carboxyacetyl)-N-(2,6-dimethylphenyl)-DL-alanine-13C3
|
Isotope-Labeled Compounds
|
Others
|
|
Benalaxyl metabolite M2- 13C3 (N-(Carboxyacetyl)-N-(2,6-dimethylphenyl)-DL-alanine- 13C3) is 13C labeled Benalaxyl metabolite M2 .
|
-
- HY-166934S
-
-
- HY-W779193
-
|
|
Isotope-Labeled Compounds
|
Cancer
|
|
2-Amino-3-methyl-3H-imidazo[4,5-f]quinoline-2- 13C is 13C labeled 2-Ammo-3-memyl-imidazo-[4,5-f]-quinoIine. 2-Ammo-3-memyl-imidazo-[4,5-f]-quinoIine is a mutagenic compound .
|
-
![2-Amino-3-methyl-3H-imidazo[4,5-f]quinoline-2-13C](//file.medchemexpress.eu/product_pic/hy-w779193.gif)
- HY-165694S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
2-Carbamoyl-3,5,6-trichloro-4-cyanobenzenesulfonate (sodium)- 13C2, 15N2 is 13C and 15N labeled 2-Carbamoyl-3,5,6-trichloro-4-cyanobenzenesulfonate (sodium) .
|
-
- HY-W728206S
-
-
- HY-165696S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
2,4-Dicarbamoyl-3,5,6-trichlorobenzenesulfonate (sodium)- 13C2, 15N2 is 13C and 15N labeled 2,4-Dicarbamoyl-3,5,6-trichlorobenzenesulfonate (sodium) .
|
-
- HY-13966S3
-
|
2-DG-13C6; 2-Deoxy-D-arabino-hexose-13C6; D-Arabino-2-deoxyhexose-13C6
|
Isotope-Labeled Compounds
Apoptosis
Hexokinase
HSV
|
Cancer
|
|
2-Deoxy-D-glucose- 13C6 (2-DG- 13C6) is 13C labeled 2-Deoxy-D-glucose. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase .
|
-
- HY-110382S
-
|
13C20,15N10-c-di-GMP, 13C20,15N10-Cyclic diguaylate, 13C20,15N10-3’,5’-Cyclic diguaylic Acid
|
Isotope-Labeled Compounds
Endogenous Metabolite
STING
|
Cancer
|
|
13C20, 15N10-Cyclic di-GMP ( 13C20, 15N10-c-di-GMP) is 13C and 15N labeled Cyclic-di-GMP (disodium). Cyclic-di-GMP disodium is a STING agonist and a bacterial second messenger that coordinates different aspects of bacterial growth and behavior, including motility, virulence, biofilm formation, and cell cycle progression. Cyclic-di-GMP disodium has anti-cancer cell proliferation activity and also induces elevated CD4 receptor expression and cell cycle arrest. Cyclic-di-GMP disodium can be used in cancer research .
|
-
- HY-W748354
-
|
2,2',4,4',6,6'-Hexachlorobiphenyl-13C12
|
Isotope-Labeled Compounds
|
Others
|
|
2,2',4,4',6,6'-Hexachloro-1,1'-biphenyl- 13C12 (2,2',4,4',6,6'-Hexachlorobiphenyl- 13C12) is 13C labeled 2,2',4,4',6,6'-Hexachloro-1,1'-biphenyl .
|
-
- HY-W748355
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
2,2',3,3',5,5',6,6'-Octachloro-1,1'-biphenyl- 13C12 is 13C labeled 2,2',3,3',5,5',6,6'-Octachloro-1,1'-biphenyl .
|
-
- HY-W778058
-
-
- HY-W777335
-
-
- HY-W777964
-
-
- HY-166894S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
3,3′,4,4′,5,5′-Hexabromo diphenyl ether- 13C12 is 13C labeled 3,3′,4,4′,5,5′-Hexabromo diphenyl ether .
|
-
- HY-W778391
-
|
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Cardiovascular Disease
Endocrinology
|
|
Bisphenol A- 13C2 is 13C labeled Bisphenol A. Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders .
|
-
- HY-W778393
-
-
- HY-14879S2
-
|
NXL-104-13C5
|
Isotope-Labeled Compounds
Antibiotic
Beta-lactamase
Bacterial
|
Infection
|
|
Avibactam sodium salt- 13C5 (NXL-104- 13C5) is 13C labeled Avibactam (sodium). Avibactam sodium (NXL-104) is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactamase TEM-1 and CTX-M-15 with IC50s of 8 nM and 5 nM, respectively .
|
-
- HY-166959S
-
-
- HY-166931S
-
-
- HY-166909S
-
-
- HY-B0136S
-
|
FK-482-13C,15N2; CI-983-13C,15N2
|
Isotope-Labeled Compounds
Antibiotic
Bacterial
|
Infection
|
|
Cefdinir- 13C, 15N2 (FK-482- 13C, 15N2) is 13C and 15N labeled Cefdinir. Cefdinir (FK-482) is a semi-synthetic, broad-spectrum antibiotic in the third generation of the cephalosporin class, which is proved to be effective for infections caused by several Gram-negative and Gram-positive bacteria. Cefdinir can be used for the research of common bacterial infections of the ear, sinus, throat, and skin .
|
-
- HY-W719722
-
-
- HY-W700491
-
|
2-Amino-α-carboline-15N3; AαC-15N3
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Cancer
|
|
AalphaC- 15N3 (2-Amino-α-carboline- 15N3) is 15N labeled AalphaC. AalphaC (AαC) is a potential carcinogen with carcinogenic activity. AalphaC is an important biomarker in tobacco smoke and is associated with tobacco smoke exposure. Urinary concentrations of AalphaC are significantly higher in dedicated smokers than in non-smokers, indicating its importance in monitoring tobacco exposure. AalphaC levels increase significantly with increasing serum nicotine levels, indicating its close relationship with tobacco use. In addition, consuming high-temperature cooked beef significantly increases the amount of AalphaC in urine, while consuming vegetables is associated with a decrease in AalphaC concentrations. Smoking half a pack of cigarettes is associated with a significant increase in the amount of AalphaC, which further confirms the biological activity of AalphaC and its association with dietary habits .
|
-
- HY-W699983
-
|
Glyoxaline-15N2; 1,3-Diaza-2,4-cyclopentadiene-15N2
|
Isotope-Labeled Compounds
Thrombopoietin Receptor
Ser/Thr Protease
|
Neurological Disease
Inflammation/Immunology
|
|
Imidazole- 15N2 (Glyoxaline- 15N2) is 15N labeled Imidazole. Imidazole (Glyoxaline; 1,3-Diaza-2,4-cyclopentadiene) is a heterocyclic aromatic compound. Imidazole bearing molecules have been used as corrosion, acetylcholinesterase (AChEI) and xanthine oxidase (XO) inhibitors, performing biological activities such as antifungal, antituberculosis, anti-inflammatory, antioxidant, and analgesic, amongst many others. Imidazole inhibits the enzymatic conversion of the endoperoxides (PGG2 and PGH2) to thromboxane A2 by platelet microsomes. Imidazole derivatives exhibits inhibition on SARS-CoV-2 3CL Pro enzyme, which is promising for research in the field of Alzheimer’s disease, gout, COVID-19 and thrombo-embolic disease .
|
-
- HY-166904S
-
-
- HY-166926S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
2,2′,3,4,5,5′-Hexachloro diphenyl ether- 13C12 is 13C labeled 2,2′,3,4,5,5′-Hexachloro diphenyl ether .
|
-
- HY-W748705
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
Aminomethanephosphonic acid- 13C, 15N is 13C and 15N labeled (((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)methyl)phosphonic acid .
|
-
- HY-W748299
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
1, 2, 3, 6, 7, 8-Hexachloro-dibenzofuran- 13C12 is 13C labeled 1, 2, 3, 6, 7, 8-Hexachloro-dibenzofuran .
|
-
- HY-W748291
-
|
2,3,4,4',5-Pentachlorobiphenyl-13C12
|
Isotope-Labeled Compounds
|
Others
|
|
2,3,4,4',5-Pentachloro-1,1'-biphenyl- 13C12 (2,3,4,4',5-Pentachlorobiphenyl- 13C12) is 13C labeled 2,3,4,4',5-Pentachloro-1,1'-biphenyl .
|
-
- HY-W748303
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
1, 2, 3, 7, 8, 9-Hexachloro-dibenzofuran- 13C12 is 13C labeled 1, 2, 3, 7, 8, 9-Hexachloro-dibenzofuran .
|
-
- HY-W748314
-
-
- HY-W748328
-
|
|
Isotope-Labeled Compounds
Autophagy
Proteasome
|
Cancer
|
|
Ixazomib- 13C2, 15N is 13C and 15N labeled Ixazomib. Ixazomib (MLN2238) is a selective, potent, and reversible proteasome inhibitor, which inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome with an IC50 of 3.4 nM (Ki of 0.93 nM) .
|
-
- HY-W748332
-
|
CDE-99-13C12; PCB No 118-13C12; 2,3',4,4',5-Pentachlorobiphenyl-13C12
|
Isotope-Labeled Compounds
|
Others
|
|
PCB118- 13C12 (CDE-99- 13C12; PCB No 118- 13C12; 2,3',4,4',5-Pentachlorobiphenyl- 13C12) is 13C labeled PCB118 .
|
-
- HY-W748349
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
2,2',3,3',4,4',5,5'-Octachloro-1,1'-biphenyl- 13C12 is 13C labeled 2,2',3,3',4,4',5,5'-Octachloro-1,1'-biphenyl .
|
-
- HY-166897S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
1,2,3,4,8,9-Hexachlorodibenzofuran- 13C12 is 13C labeled 1,2,3,4,8,9-Hexachlorodibenzofuran .
|
-
- HY-W748282
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
2,3,3',4,4',5,5',6-Octachloro-1,1'-biphenyl- 13C12 is 13C labeled 2,3,3',4,4',5,5',6-Octachloro-1,1'-biphenyl .
|
-
- HY-W748284
-
|
2,4,4'-Trichlorobiphenyl-13C12
|
Isotope-Labeled Compounds
|
Others
|
|
2,4,4'-Trichloro-1,1'-biphenyl- 13C12 (2,4,4'-Trichlorobiphenyl- 13C12) is 13C labeled 2,4,4'-Trichloro-1,1'-biphenyl .
|
-
- HY-W746828
-
-
- HY-W749756
-
-
- HY-166899S
-
-
- HY-166922S
-
-
- HY-166929S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
2,2′,3,4′,5,5′,6-Heptachloro-4-methoxy biphenyl- 13C12 is 13C labeled 2,2′,3,4′,5,5′,6-Heptachloro-4-methoxy biphenyl .
|
-
- HY-166923S
-
-
- HY-166925S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
2′,3,3′,4′,5,5′-Hexachloro-4-biphenylol- 13C12 is 13C labeled 2′,3,3′,4′,5,5′-Hexachloro-4-biphenylol .
|
-
- HY-166936S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
1,2,3,4,5,6,8-Heptachloronaphthalene- 13C10 is 13C labeled 1,2,3,4,5,6,8-Heptachloronaphthalene .
|
-
- HY-166945S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
2,3,3′,4,5,5′-Hexachloro-4′-methoxy biphenyl- 13C12 is 13C labeled 2,3,3′,4,5,5′-Hexachloro-4′-methoxy biphenyl .
|
-
- HY-166939S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
3,4,5,6-Tetrabromo[1,1′-biphenyl]-2,2′-diol- 13C12 is 13C labeled 3,4,5,6-Tetrabromo[1,1′-biphenyl]-2,2′-diol .
|
-
![3,4,5,6-Tetrabromo[1,1′-biphenyl]-2,2′-diol-13C12](//file.medchemexpress.eu/product_pic/hy-166939s.gif)
- HY-166940S
-
-
- HY-166950S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
2,2′,3,4,4′,6-Hexabromo diphenyl ether- 13C12 is 13C labeled 2,2′,3,4,4′,6-Hexabromo diphenyl ether .
|
-
- HY-166958S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
1,2,3,4,6,7,9-Heptachloro dibenzo-p-dioxin- 13C12 is 13C labeled 1,2,3,4,6,7,9-Heptachloro dibenzo-p-dioxin .
|
-
- HY-W653930
-
|
Bisphenol S-13C12; Bis(4-hydroxyphenyl) sulfone-13C12
|
Isotope-Labeled Compounds
Biochemical Assay Reagents
|
Others
|
|
4,4'-Sulfonyldiphenol- 13C12 (Bisphenol S- 13C12) is 13C labeled 4,4'-Sulfonyldiphenol. 4,4'-Sulfonyldiphenol (Bisphenol S; Bis(4-hydroxyphenyl) sulfone) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
|
-
- HY-W653962
-
|
|
Isotope-Labeled Compounds
Apoptosis
Antibiotic
Fungal
Bacterial
|
Infection
Cancer
|
|
Triclosan- 13C6 is 13C labeled Triclosan. Triclosan is a broad-spectrum antibacterial agent that inhibits bacterial fatty acid synthesis at the enoyl-acyl carrier protein reductase (FabI) step. Triclosan inhibits E. coli enoyl-acyl carrier protein reductase (FabI) and FabI containing a glycine-to-valine substitution at position 93 (FabIG93V) with IC50s of 2 μM and 10 μM, respectively. Triclosan causes apoptotic effect in cultured rat neural stem cells (NSC). Triclosan exacerbates colitis and colitis-associated colorectal tumorigenesis in animal models .
|
-
- HY-W653994
-
|
Ethyl parahydroxybenzoate-13C6; Ethyl 4-hydroxybenzoate-13C6
|
Isotope-Labeled Compounds
|
Others
|
|
Ethyl Paraben- 13C6 (Ethyl parahydroxybenzoate- 13C6) is 13C labeled Ethylparaben. Ethylparaben is the ethyl ester of paraben and is used as an antifungal preservative and food additive .
|
-
- HY-W654020
-
|
Propyl parahydroxybenzoate-13C6; Propyl 4-hydroxybenzoate-13C6
|
Isotope-Labeled Compounds
Apoptosis
Endogenous Metabolite
Bacterial
|
Infection
|
|
Propyl paraben- 13C6 (Propyl parahydroxybenzoate- 13C6) is 13C labeled Propylparaben. Propylparaben (Propyl parahydroxybenzoate) is an antibacterial preservative that can be produced by plants and bacteria. Propylparaben is commonly used in cosmetics, pharmaceuticals and foods. Propylparaben disrupts follicular growth and steroidogenic function by altering cell cycle, apoptosis and steroidogenic pathways. Propylparaben also reduced sperm count and motility in rats .
|
-
- HY-W654041
-
-
- HY-W654118
-
-
- HY-W654126
-
|
Cytosine β-D-arabinofuranoside--13C3; Cytosine Arabinoside--13C3; Ara-C-13C3
|
Isotope-Labeled Compounds
|
Others
|
|
Cytarabine- 13C3 (Cytosine β-D-arabinofuranoside- 13C3) is 13C labeled Cytarabine .
|
-
- HY-W654258
-
-
- HY-W654304
-
-
- HY-W779296
-
|
Potassium rhodanide-13C,15N
|
Isotope-Labeled Compounds
|
Others
|
|
Potassium thiocyanate- 13C, 15N (Potassium rhodanide- 13C, 15N) is 13C and 15N labeled Potassium thiocyanate .
|
-
- HY-W770410
-
-
- HY-W770434
-
-
- HY-W770295
-
-
- HY-W769017
-
-
- HY-W768398
-
-
- HY-W767866
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
N-Acetyl-S-(2-carboxyethyl)cysteine- 13C3 (dicyclohexylamine) is 13C labeled N-Acetyl-S-(2-carboxyethyl)cysteine (dicyclohexylamine) .
|
-
- HY-W767228
-
-
- HY-W778144
-
-
- HY-W778183
-
-
- HY-W778142
-
-
- HY-W753532
-
-
- HY-W777533
-
-
- HY-W777360
-
|
|
Isotope-Labeled Compounds
Adrenergic Receptor
Monoamine Oxidase
nAChR
Opioid Receptor
Imidazoline Receptor
GABA Receptor
|
Neurological Disease
Inflammation/Immunology
|
|
Harman- 13C2, 15N is 13C and 15N labeled Harmane. Harmane is a benzodiazepine receptor inhibitor (IC50=7 μM), with IC50 values for mACh, Opioid Receptor, MAO-A/B, and α2-adrenergic receptor of 24 μM, 2.8 μM, 0.5 μM, 5 μM, and 18 μM, respectively. Harmane also inhibits haloperidol and serotonin, with IC50 values of 163 μM and 101 μM, respectively. Harmane inhibits the I1 imidazoline receptor (IC50=30 nM) to reduce blood pressure and has antidepressant, anti-anxiety, anticonvulsant, and analgesic effects. Harmane inhibits dopamine biosynthesis by decreasing tyrosine hydroxylase (TH) activity and enhancing L-DOPA-induced cytotoxicity in PC12 cells. Additionally, Harmane can increase the mutagenic effect induced by 2-acetylaminofluorene (AAF) .
|
-
- HY-W777148
-
-
- HY-W777161
-
-
- HY-W780180
-
-
- HY-166919S
-
-
- HY-166924S
-
-
- HY-166895S
-
-
- HY-165695S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
2-Carbamoyl-3,5,6-trichloro-4-cyanobenzenesulfonate (sodium)- 15N2 is 15N labeled 2-Carbamoyl-3,5,6-trichloro-4-cyanobenzenesulfonate (sodium) .
|
-
- HY-166893S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
1,2,3,6,7,8-Hexachloronaphthalene- 13C10 is 13C labeled 1,2,3,6,7,8-Hexachloronaphthalene .
|
-
- HY-166901S
-
-
- HY-166915S
-
-
- HY-166953S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
1,2,3,4,6,8-Hexachloro-dibenzo-p-dioxin- 13C12 is 13C labeled 1,2,3,4,6,8-Hexachloro-dibenzo-p-dioxin .
|
-
- HY-59354S1
-
|
1,2-Dihydro-3,6-pyridazine-13C4-dione; 3,6-Dihydroxypyridazine-13C4; 3,6-Pyridazine-13C4-diol; Maleic hydrazide-13C4
|
Isotope-Labeled Compounds
DNA/RNA Synthesis
|
Cancer
|
|
1,2-Dihydropyridazine-3,6-dione-3,4,5,6- 13C4 (1,2-Dihydro-3,6-pyridazine- 13C4-dione) is 13C labeled Maleic hydrazide. Maleic hydrazide is extensively used as a systemic plant growth regulator and as a herbicide. Maleic hydrazide acts as an inhibitor of the synthesis of nucleic acids and proteins .
|
-
- HY-B1892S1
-
-
- HY-W012507S1
-
-
- HY-165691S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
Chlorothalonil Metabolite R611553- 13C2, 15N2 (sodium salt) is 13C and 15N labeled Chlorothalonil Metabolite R611553 (sodium salt) .
|
-
- HY-W011297S3
-
|
Arachidonic acid methyl ester-13C5
|
Isotope-Labeled Compounds
Others
|
Metabolic Disease
|
|
Methyl arachidonate- 13C5 (Arachidonic acid methyl ester- 13C5) is 13C labeled Methyl arachidonate. Methyl arachidonate (Arachidonic acid methyl ester) is a fatty acid methyl ester resulting from the formal condensation of the carboxy group of arachidonic acid with methanol. Methyl arachidonate has activity of human blood serum metabolite .
|
-
- HY-W128657S
-
|
2-Hydroxy-3-chloropropionic Acid-13C3
|
Isotope-Labeled Compounds
|
Others
|
|
3-Chloro-2-hydroxypropanoic acid- 13C3 (2-Hydroxy-3-chloropropionic Acid- 13C3) is 13C labeled 3-Chloro-2-hydroxypropanoic acid .
|
-
- HY-B2167S2
-
-
- HY-14894S2
-
|
ASP1941-13C6
|
Isotope-Labeled Compounds
SGLT
|
Metabolic Disease
|
|
Pragliflozin- 13C6 (ASP1941- 13C6) is 13C labeled Ipragliflozin. Ipragliflozin (ASP1941) is an orally active and selective SGLT2 inhibitor with IC50s of 7.38 and 1876 nM, 6.73 and 1166 nM, 5.64 and 1380 nM for human SGLT2 and SGLT1, rat SGLT2 and SGLT1, mouse SGLT2 and SGLT1, respectively. Antidiabetic agent .
|
-
- HY-113455S1
-
|
(+)-α-Dimophecolic acid-13C18
|
Isotope-Labeled Compounds
Endogenous Metabolite
Apoptosis
|
Cancer
|
|
9(S)-HODE- 13C18 ((+)-α-Dimophecolic acid- 13C18) is 13C labeled 9S-HODE. 9S-HODE (Alpha-dimorphecolic acid) is an octadecadienoic acid and the main active derivative of linoleic acid, which can reduce the viability of HL-60 cells and induce apoptosis. 9S-HODE is rich in lipid peroxidation (LPO) products and is almost an ideal marker for LPO .
|
-
- HY-B0660S1
-
|
EPA 1,2,3,4,5-13C, FA 20:5-13C5
|
Isotope-Labeled Compounds
Endogenous Metabolite
Histone Demethylase
|
Neurological Disease
Cancer
|
|
Eicosapentaenoic acid 1,2,3,4,5- 13C5 (EPA 1,2,3,4,5- 13C, FA 20:5- 13C5) is 13C labeled Eicosapentaenoic Acid. Eicosapentaenoic Acid (EPA) is an orally active Omega-3 long-chain polyunsaturated fatty acid (ω-3 LC-PUFA). Eicosapentaenoic Acid exhibits a DNA demethylating action that promotes the re-expression of the tumor suppressor gene CCAAT/enhancer-binding protein δ (C/EBPδ). Eicosapentaenoic Acid activates RAS/ERK/C/EBPβ pathway through H-Ras intron 1 CpG island demethylation in U937 leukemia cells. Eicosapentaenoic Acid can promote relaxation of vascular smooth muscle cells and vasodilation .
|
-
- HY-166960S
-
-
- HY-166961S
-
-
- HY-166900S
-
-
- HY-166889S
-
-
- HY-N7082S
-
|
|
Isotope-Labeled Compounds
Others
|
Infection
|
|
D- Arabinose- 13C5 is 13C labeled D- Arabinose. D-Arabinose, a monosaccharide, shows strong growth inhibition against the Caenorhabditis elegans with an IC50 of 7.5 mM .
|
-
- HY-166933S
-
-
- HY-166927S
-
-
- HY-166912S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
1,2,3,5,6,7-Hexachloro-naphthalene- 13C10 is 13C labeled 1,2,3,5,6,7-Hexachloro-naphthalene .
|
-
- HY-166914S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
2,2',3,3',4,5,5'-Heptachloro-4'-methoxybiphenyl- 13C12 is 13C labeled 2,2',3,3',4,5,5'-Heptachloro-4'-methoxybiphenyl .
|
-
- HY-166903S
-
-
- HY-166918S
-
-
- HY-166962S
-
-
- HY-10450S5
-
|
|
Isotope-Labeled Compounds
SGLT
|
Metabolic Disease
Cancer
|
|
Dapagliflozin- 13C6-1 is 13C labeled Dapagliflozin. Dapagliflozin (BMS-512148), a new type of agent used to treat diabetes mellitus (DM), is a competitive sodium/glucose cotransporter 2 (SGLT2) inhibitor, which results in excretion of glucose into the urine . Dapagliflozin induces HIF1 expression and attenuates renal IR injury .
|
-
- HY-166920S
-
-
- HY-166935S
-
-
- HY-166942S
-
-
- HY-166948S
-
-
- HY-166949S
-
-
- HY-166952S
-
-
- HY-166951S
-
-
- HY-W010450S5
-
|
5-Methyluacil-13C5,15N,15N2
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Metabolic Disease
Cancer
|
|
Thymine- 13C5, 15N2 (5-Methyluacil- 13C5, 15N2) is 13C and 15N labeled Thymine. Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a Km of 2.3 μM .
|
-
- HY-W010256S3
-
-
- HY-W753141
-
|
4,4'-DDE-13C12; p,p'-Dichlorodiphenyldichloroethylene-13C12
|
Isotope-Labeled Compounds
Androgen Receptor
Drug Metabolite
|
Endocrinology
|
|
p,p'-DDE- 13C12 is 13C labeled p,p'-DDE. p,p'-DDE (4,4'-DDE), a major metabolite of persistent dichlorodiphenyltrichloroethane (DDT), is a potent androgen receptor antagonist, with an IC50 of 5 μM and a Ki of 3.5 μM .
|
-
- HY-W779345
-
-
- HY-W015466S1
-
-
- HY-P0265AS
-
|
Amyloid Beta-Peptide-15N (1-40) (human) TFA; Amyloid β-Peptide-15N (1-40) (human) TFA
|
Amyloid-β
|
Neurological Disease
|
|
β-Amyloid- 15N (1-40) (TFA) is the 15N-labledβ-Amyloid (1-40) (TFA). β-Amyloid (1-40) is a primary protein in plaques found in the brains of patients with Alzheimer's disease[1].
|
-
- HY-P1363S
-
|
Amyloid β-peptide-15N (1-42) (human) TFA
|
Amyloid-β
|
Neurological Disease
|
|
β-Amyloid- 15N (1-42), human (TFA) is the 15N-labledβ-Amyloid (1-42) (TFA). β-Amyloid (1-42), human TFA (Amyloid β-Peptide (1-42) (human) TFA) is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease[1].
|
-
- HY-P3146S
-
|
|
Isotope-Labeled Compounds
|
Cancer
|
|
FTISADTSK- 13C6, 15N2 TFA is 13C- and 15N-labeled FTISADTSK (HY-P3146). FTISADTSK is an endogenous stable signature peptide from Trastuzumab monitored by selected reaction monitoring (SRM) .
|
-
- HY-P0014S1
-
|
|
Isotope-Labeled Compounds
GLP Receptor
GCGR
|
Others
|
|
Liraglutide- 13C5, 15N (tetraTFA) is the 13C and 15N labeled Liraglutide (HY-P0014) . Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used clinically to treat type 2 diabetes mellitus .
|
-
- HY-P2625S1
-
|
|
Isotope-Labeled Compounds
GCGR
|
Metabolic Disease
|
|
GLP-2(3-33) (Leu- 13C6, 15N) TFA is 13C and 15N labeled GLP-2(3-33) (HY-P2625). GLP-2(3-33), generated naturally by dipeptidylpeptidase IV (DPPIV), acts as a partial agonist on GLP-2 receptor (EC50=5.8 nM).
|
-
- HY-P1142S1
-
|
|
Isotope-Labeled Compounds
Apoptosis
|
Others
|
|
GLP-2(rat) (Ala- 13C3, 15N) TFA is 13C and 15N labeled GLP-2(rat) (HY-P1142). GLP-2(rat) is an intestinal growth factor. GLP-2(rat) stimulates cell proliferation and inhibits apoptosis. GLP-2(rat) enhances mucosal mass and function in residual small intestine after massive small bowel resection (MSBR).
|
-
- HY-P1142S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
GLP-2(rat) (Ala- 13C3, 15N) is 13C and 15N labeled GLP-2(rat) (HY-P1142). GLP-2(rat) is an intestinal growth factor. GLP-2(rat) stimulates cell proliferation and inhibits apoptosis. GLP-2(rat) enhances mucosal mass and function in residual small intestine after massive small bowel resection (MSBR).
|
-
- HY-P2625S
-
|
|
Isotope-Labeled Compounds
|
Metabolic Disease
|
|
GLP-2(3-33) (Leu- 13C6, 15N) is 13C and 15N labeled GLP-2(3-33) (HY-P2625). GLP-2(3-33), generated naturally by dipeptidylpeptidase IV (DPPIV), acts as a partial agonist on GLP-2 receptor (EC50=5.8 nM).
|
-
- HY-156341S1
-
-
- HY-156343S1
-
-
- HY-156344S1
-
-
- HY-156345S1
-
-
- HY-P5201S1
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
VTSEGAGLQLQK- 13C6, 15N2 (TFA) is the 13C- and 15N-labeled VTSEGAGLQLQK. VTSEGAGLQLQK is an amino acid sequence in the C-terminal region of recombinant human alpha-acid glucosidase (rhGAA), which can be used to bind anti-drug antibodies in plasma and quantitatively analyze the therapeutic effect .
|
-
- HY-P0014S2
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
Liraglutide- 13C6, 15N (TFA)is the 13C and 15N labeledLiraglutide(HY-P0014). Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used clinically to treat type 2 diabetes mellitus .
|
-
- HY-163426S
-
-
- HY-163427S
-
-
- HY-163423S
-
-
- HY-163422S
-
-
- HY-163424S
-
-
- HY-163425S
-
-
- HY-P1032S
-
|
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Others
|
|
Angiotensin I- 13C19, 15N3 (human, mouse, rat) is the 13C and 15N labeled Angiotensin I (human, mouse, rat) (HY-P1032). Cellulose (Pectin glycosidase) is a natural high molecular weight polysaccharide found in many plants and organisms. It is widely used in manufacturing industries, such as in paper making, textiles, food and medicine, etc. As a renewable resource, Cellulose is biodegradable and sustainable, and can also be used to manufacture chemicals such as Cellulose Esters, Cellulose Acetate and Cellulose Nitrate. In addition, Cellulose is often used as a food additive to increase the stability and quality of food .
|
-
- HY-158994S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
MEGDSRGG-(Ala- 13C3, 15N)-GGEA-(Leu- 13C6, 15N)-DPESAASSLSGAS TFA is a 13C- and 15N-labeled peptide containing 13C3, 15N-labeled alanine (Ala) and 13C6, 15N-labeled leucine (Leu).
|
-
- HY-158992S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
SP-(Val- 13C5, 15)-EKNQ-(Leu- 13C6, 15)-TIDFINIVKDPVPHNEYKT TFA is a 13C- and 15N-labeled peptide containing 13C5, 15N-labeled valine (Val) and 13C6, 15N-labeled leucine (Leu).
|
-
- HY-P3207S
-
-
- HY-P1033S
-
-
![[Pyr1]-Apelin-13, Gly(15N) TFA](//file.medchemexpress.eu/product_pic/hy-p1033s.gif)
- HY-P6421S
-
-
- HY-P6422S
-
-
- HY-P6424S
-
-
- HY-P6425S
-
-
- HY-P6423S
-
-
- HY-P1032S2
-
|
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Others
|
|
Angiotensin I-13C6,15N (human, mouse, rat) TFA is 13C and 15N labeled Angiotensin I (human, mouse, rat) TFA. Angiotensin I-13C6,15N (human, mouse, rat) TFA is a precursor of angiotensin II and is cleaved into angiotensin II by angiotensin converting enzyme (ACE) .
|
-
- HY-P0090S
-
|
Salmon calcitonin-13C6,15N4 TFA
|
CGRP Receptor
|
Metabolic Disease
|
|
Calcitonin- 13C6, 15N4 (salmon) (Salmon calcitonin- 13C6, 15N4) TFA is 13C and 15N-labeled Calcitonin (salmon) (HY-P0090). Calcitonin (salmon) , a calcium regulating hormone, is a dual-action amylin and calcitonin receptor agonist, could stimulate bone formation and inhibit bone resorption .
|
-
- HY-W127841
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Citric acid-2,4-13C2 (Sodium Lauryl Sulfate) is a labeled citric acid. Citric acid is found in many fruits and vegetables, especially citrus fruits. It participates in biological processes in the body, such as the citric acid cycle.
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-W127841
-
|
|
Biochemical Assay Reagents
|
|
Citric acid-2,4-13C2 (Sodium Lauryl Sulfate) is a labeled citric acid. Citric acid is found in many fruits and vegetables, especially citrus fruits. It participates in biological processes in the body, such as the citric acid cycle.
|
-
- HY-W088413A
-
|
|
Chelators
|
|
DOTA-amide (dihydrate) is a Bifunctional Chelators (BFCs). DOTA-amide (dihydrate) binds to the Affibody molecule ZHER2:S1. Its complex binds specifically to HER2 and can be used to detect bone metastases, which are common in prostate cancer .
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-159191S
-
-
- HY-159192S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
SADDNIKTPAE(Arg- 13C6, 15N4)LLGPLPPSADDNLKT (TFA) is the 13C and 15N labeled isotope of SADDNIKTPAE-LLGPLPPSADDNLKT (TFA) .
|
-
- HY-159193S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
DHATS(Leu- 13C6, 15N)PVTIPSAVST(Gly- 13C2, 15N)HTTPLPVTDT (TFA) is the 13C and 15N labeled isotope of DHATS-PVTIPSAVST-HTTPLPVTDT (TFA) .
|
-
- HY-P1033S1
-
-
- HY-159046S
-
-
- HY-163992S
-
-
- HY-163993S
-
-
- HY-159064S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
DSPSAPVNVT(Val- 13C5, 15)R TFA is the 13C and 15N-labeled DSPSAPVNVT(Val)R. Radioactive isotopes labeled compounds can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified .
|
-
- HY-159065S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
FIQE(Val- 13C5, 15N)NTTTR TFA is the 13C and 15N-labeled FIQE(Val)NTTTR. Radioactive isotopes labeled compounds can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified .
|
-
- HY-P5053
-
-
- HY-P5290
-
|
|
Radionuclide-Drug Conjugates (RDCs)
PSMA
|
Cancer
|
|
HYNIC-PSMA is a ligand for molecular imaging of tumors. Hynic-psma consists of two components: HYNIC (6-hydrazinonicotinamide) and PSMA (Prostate-Specific Membrane Antigen). HYNIC is a compound used to attach radioactive isotopes to targeted molecules, such as 188Re-HYNIC-PSMA. PSMA is a membrane antigen that is specifically expressed on the surface of prostate cancer cells. HYNIC-PSMA can be used in prostate cancer research .
|
-
- HY-P5292
-
|
|
Radionuclide-Drug Conjugates (RDCs)
PSMA
|
Cancer
|
|
HYNIC-iPSMA is a ligand for molecular imaging of tumors. Hynic-ipsma consists of two components: HYNIC (6-hydrazinonicotinamide) and iPSMA (Inhibitor of Prostate-Specific Membrane Antigen). HYNIC is a compound used to attach radioactive isotopes to targeted molecules. iPSMA is a specific inhibitor used to inhibit prostate-specific membrane antigen (PSMA). 68GA-labeled iPSMA has been used to detect prostate cancer by PET imaging. The further 99mTc-EDDA/HYNIC-iPSMA has excellent specificity and sensitivity .
|
-
- HY-P5292A
-
|
|
Radionuclide-Drug Conjugates (RDCs)
PSMA
|
Cancer
|
|
HYNIC-iPSMA TFA is a ligand for molecular imaging of tumors. Hynic-ipsma consists of two components: HYNIC (6-hydrazinonicotinamide) and iPSMA (Inhibitor of Prostate-Specific Membrane Antigen). HYNIC is a compound used to attach radioactive isotopes to targeted molecules. iPSMA is a specific inhibitor used to inhibit prostate-specific membrane antigen (PSMA). 68GA-labeled iPSMA has been used to detect prostate cancer by PET imaging. The further 99mTc-EDDA/HYNIC-iPSMA TFA has excellent specificity and sensitivity .
|
-
- HY-P5126
-
|
|
Radionuclide-Drug Conjugates (RDCs)
Somatostatin Receptor
|
Cancer
|
|
DOTA-LM3 is a somatostatin receptor (SSTR) antagonist. LM3 refers to p-Cl-Phe- cyclo(D-Cys-Tyr-D-4-amino-Phe(carbamoyl)-Lys-Thr-Cys)D-Tyr- NH2, as well as a somatostatin antagonist. DOTA-LM3 is often isotopically labeled for tracing tumors in vivo, such as 177Lu-DOTA-LM3 and 68 Ga-DOTA-LM3. 68 Ga-DOTA-LM3 shows favorable biodistribution, high tumor uptake, good tumor retention, and few safety concerns. 177Lu-DOTA-LM3 can be used for research in DOTATOC-negative liver metastases, such as pancreatic NET and extensive tumor thrombosis .
|
-
- HY-P5126A
-
|
|
Radionuclide-Drug Conjugates (RDCs)
Somatostatin Receptor
|
Cancer
|
|
DOTA-LM3 TFA is a somatostatin receptor (SSTR) antagonist. LM3 refers to p-Cl-Phe- cyclo(D-Cys-Tyr-D-4-amino-Phe(carbamoyl)-Lys-Thr-Cys)D-Tyr- NH2, as well as a somatostatin antagonist. DOTA-LM3 TFA is often isotopically labeled for tracing tumors in vivo, such as 177Lu-DOTA-LM3 TFA and 68 Ga-DOTA-LM3 TFA. 68 Ga-DOTA-LM3 TFA shows favorable biodistribution, high tumor uptake, good tumor retention, and few safety concerns. 177Lu-DOTA-LM3 TFA can be used for research in DOTATOC-negative liver metastases, such as pancreatic NET and extensive tumor thrombosis .
|
-
- HY-P0265AS
-
|
Amyloid Beta-Peptide-15N (1-40) (human) TFA; Amyloid β-Peptide-15N (1-40) (human) TFA
|
Amyloid-β
|
Neurological Disease
|
|
β-Amyloid- 15N (1-40) (TFA) is the 15N-labledβ-Amyloid (1-40) (TFA). β-Amyloid (1-40) is a primary protein in plaques found in the brains of patients with Alzheimer's disease[1].
|
-
- HY-P1363S
-
|
Amyloid β-peptide-15N (1-42) (human) TFA
|
Amyloid-β
|
Neurological Disease
|
|
β-Amyloid- 15N (1-42), human (TFA) is the 15N-labledβ-Amyloid (1-42) (TFA). β-Amyloid (1-42), human TFA (Amyloid β-Peptide (1-42) (human) TFA) is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease[1].
|
-
- HY-P3146S
-
|
|
Isotope-Labeled Compounds
|
Cancer
|
|
FTISADTSK- 13C6, 15N2 TFA is 13C- and 15N-labeled FTISADTSK (HY-P3146). FTISADTSK is an endogenous stable signature peptide from Trastuzumab monitored by selected reaction monitoring (SRM) .
|
-
- HY-P0014S1
-
|
|
Isotope-Labeled Compounds
GLP Receptor
GCGR
|
Others
|
|
Liraglutide- 13C5, 15N (tetraTFA) is the 13C and 15N labeled Liraglutide (HY-P0014) . Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used clinically to treat type 2 diabetes mellitus .
|
-
- HY-P2625S1
-
|
|
Isotope-Labeled Compounds
GCGR
|
Metabolic Disease
|
|
GLP-2(3-33) (Leu- 13C6, 15N) TFA is 13C and 15N labeled GLP-2(3-33) (HY-P2625). GLP-2(3-33), generated naturally by dipeptidylpeptidase IV (DPPIV), acts as a partial agonist on GLP-2 receptor (EC50=5.8 nM).
|
-
- HY-P1142S1
-
|
|
Isotope-Labeled Compounds
Apoptosis
|
Others
|
|
GLP-2(rat) (Ala- 13C3, 15N) TFA is 13C and 15N labeled GLP-2(rat) (HY-P1142). GLP-2(rat) is an intestinal growth factor. GLP-2(rat) stimulates cell proliferation and inhibits apoptosis. GLP-2(rat) enhances mucosal mass and function in residual small intestine after massive small bowel resection (MSBR).
|
-
- HY-P1142S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
GLP-2(rat) (Ala- 13C3, 15N) is 13C and 15N labeled GLP-2(rat) (HY-P1142). GLP-2(rat) is an intestinal growth factor. GLP-2(rat) stimulates cell proliferation and inhibits apoptosis. GLP-2(rat) enhances mucosal mass and function in residual small intestine after massive small bowel resection (MSBR).
|
-
- HY-P2625S
-
|
|
Isotope-Labeled Compounds
|
Metabolic Disease
|
|
GLP-2(3-33) (Leu- 13C6, 15N) is 13C and 15N labeled GLP-2(3-33) (HY-P2625). GLP-2(3-33), generated naturally by dipeptidylpeptidase IV (DPPIV), acts as a partial agonist on GLP-2 receptor (EC50=5.8 nM).
|
-
- HY-156341S1
-
-
- HY-156343S1
-
-
- HY-156344S1
-
-
- HY-156345S1
-
-
- HY-P5201S1
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
VTSEGAGLQLQK- 13C6, 15N2 (TFA) is the 13C- and 15N-labeled VTSEGAGLQLQK. VTSEGAGLQLQK is an amino acid sequence in the C-terminal region of recombinant human alpha-acid glucosidase (rhGAA), which can be used to bind anti-drug antibodies in plasma and quantitatively analyze the therapeutic effect .
|
-
- HY-P0014S2
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
Liraglutide- 13C6, 15N (TFA)is the 13C and 15N labeledLiraglutide(HY-P0014). Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used clinically to treat type 2 diabetes mellitus .
|
-
- HY-163426S
-
-
- HY-163427S
-
-
- HY-163423S
-
-
- HY-163422S
-
-
- HY-163424S
-
-
- HY-163425S
-
-
- HY-P1032S
-
|
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Others
|
|
Angiotensin I- 13C19, 15N3 (human, mouse, rat) is the 13C and 15N labeled Angiotensin I (human, mouse, rat) (HY-P1032). Cellulose (Pectin glycosidase) is a natural high molecular weight polysaccharide found in many plants and organisms. It is widely used in manufacturing industries, such as in paper making, textiles, food and medicine, etc. As a renewable resource, Cellulose is biodegradable and sustainable, and can also be used to manufacture chemicals such as Cellulose Esters, Cellulose Acetate and Cellulose Nitrate. In addition, Cellulose is often used as a food additive to increase the stability and quality of food .
|
-
- HY-P10324
-
|
p16INK4a peptide
|
Peptides
|
Cancer
|
|
TAT-p16 (p16INK4a peptide) is a peptide mimic of p16INK4a that can induce an early G phase cell cycle arrest in the absence of active cyclin E:Cdk2 complex .
|
-
- HY-158994S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
MEGDSRGG-(Ala- 13C3, 15N)-GGEA-(Leu- 13C6, 15N)-DPESAASSLSGAS TFA is a 13C- and 15N-labeled peptide containing 13C3, 15N-labeled alanine (Ala) and 13C6, 15N-labeled leucine (Leu).
|
-
- HY-158992S
-
|
|
Isotope-Labeled Compounds
|
Others
|
|
SP-(Val- 13C5, 15)-EKNQ-(Leu- 13C6, 15)-TIDFINIVKDPVPHNEYKT TFA is a 13C- and 15N-labeled peptide containing 13C5, 15N-labeled valine (Val) and 13C6, 15N-labeled leucine (Leu).
|
-
- HY-P3207S
-
-
- HY-P1033S
-
-
- HY-P6421S
-
-
- HY-P6422S
-
-
- HY-P6424S
-
-
- HY-P6425S
-
-
- HY-P6423S
-
-
- HY-P1032S2
-
|
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Others
|
|
Angiotensin I-13C6,15N (human, mouse, rat) TFA is 13C and 15N labeled Angiotensin I (human, mouse, rat) TFA. Angiotensin I-13C6,15N (human, mouse, rat) TFA is a precursor of angiotensin II and is cleaved into angiotensin II by angiotensin converting enzyme (ACE) .
|
-
- HY-P0090S
-
|
Salmon calcitonin-13C6,15N4 TFA
|
CGRP Receptor
|
Metabolic Disease
|
|
Calcitonin- 13C6, 15N4 (salmon) (Salmon calcitonin- 13C6, 15N4) TFA is 13C and 15N-labeled Calcitonin (salmon) (HY-P0090). Calcitonin (salmon) , a calcium regulating hormone, is a dual-action amylin and calcitonin receptor agonist, could stimulate bone formation and inhibit bone resorption .
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| Cat. No. |
Product Name |
Chemical Structure |
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- HY-159046S
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ASGITFSNSGMHW(Val-13C5,15N)R TFA is an isotope of ASGITFSNSGMHWVR TFA labeled with 13C and 15N .
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- HY-B2221S2
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U-13C Cellulose high DP from wheat is the cellulose (HY-B2221) isolated from wheat, that is consist of abundant glucose and all the carbon atoms are labeled with isotope 13C .
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- HY-163080S
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Selenium-77 (77Se) is a stable (non-radioactive) isotope of Selenium. Selenium-77 is both naturally occurring and produced by fission.
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- HY-Y1298S
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Methyl acetylacetate- 13C4 is an isotopically labeled compound. Methyl acetylacetate- 13C4 can be used for various biochemical studies[1].
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- HY-100807S2
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Quinolinic acid-13C4, 15N is an isotopic labeled Quinolinic acid (HY-100807). Quinolinic acid is an endogenous N-methyl-D-aspartate (NMDA) receptor agonist and has the potential of mediating NMDA neuronal damage and dysfunction .
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-
- HY-B1449S11
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Uridine-13C9 (β-Uridine-13C9) is a 13C9-labeled form of Uridine (HY-B1449). Uridine (β-Uridine) is a glycosylated pyrimidine-analog containing uracil attached to a ribose ring (or more specifically, aribofuranose) via a β-N1-glycosidic bond .
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-
-
- HY-W751961
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2'-Deoxyadenosine-15N5 is the 15N5-labeled version of 2'-Deoxyadenosine (HY-W040329). 2'-Deoxyadenosine is a nucleoside adenosine derivative that can pair with deoxythymidine in double-stranded DNA.
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-
-
- HY-W104379S
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Arprinocid-15N3 is 15N3-labeled Arprinocid (HY-W104379). Arprinocid is a purine analog with activity against murine Toxoplasma gondii .
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-
-
- HY-W269700S
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Ile-(Leu-13C6,15N)-OH (TFA) is 13C- and 15N-labeled L-Isoleucyl-L-leucine (HY-W269700). L-Isoleucyl-L-leucine has a role as a metabolite and can be used to inhibit movement-induced muscle damage and muscle defective condition.
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-
- HY-W753671
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2,6-Diaminoheptanedioic Acid-13C7 is a 13C7 labeled version of 2,6-Diaminoheptanedioic acid (HY-128746). 2,6-Diaminoheptanedioic acid is an endogenous metabolite.
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-
-
- HY-W779009
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[1-13Cglc]Lactose monohydrate is an isotopic labeling drug .
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-
- HY-N2024AS2
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Maltose monohydrate- 13C is the 13C labeled isotope of Maltose monohydrate .
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-
-
- HY-W750599
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Boron-10 is the 10B labeled isotope of Boron .
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-
- HY-N2024AS1
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Maltose monohydrate- 13C12 is the 13C labeled isotope of Maltose monohydrate .
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-
-
- HY-B1941S1
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4-tert-Octylphenol- 13C6 is the 13C labeled isotope of Octylphenol .
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-
-
- HY-B0256S1
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Azathioprine-13C4 (BW 57-322-13C4) is the 13C labeled Azathioprine (HY-B0256). Azathioprine (BW 57-322) is an orally active immunosuppressive agent. Azathioprine can be converted in vivo to the active metabolite 6-mercaptopurine (6-MP). Azathioprine has myelosuppressive effects and induces apoptosis .
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-
- HY-N0086S1
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N6-Methyladenosine- 13C is the 13C labeled isotope of N6-Methyladenosine .
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-
-
- HY-W585982S
-
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Bisphenol A β-D-Glucuronide- 13C12 is the 13C labeled isotope of Bisphenol A β-D-Glucuronide .
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-
- HY-W654023
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Tazobactam-15N3 sodium is the 15N labeled isotope of Tazobactam-15N3 sodium .
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-
-
- HY-W017401S
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Benzisothiazolinone-13C5 (1,2-Benzothiazol-3-one-13C5) is a 13C-labeled Benzisothiazolinone. Benzisothiazolinone is widely used as an antiseptic and antibacterial agent .
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-
- HY-B0892S5
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Benzyl alcohol- 13C is the 13C labeled Benzyl alcohol (HY-B0892). Benzyl alcohol is an aromatic alcohol, a colorless liquid with a mild aromatic odor .
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-
- HY-147338S1
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5-Methylcytidine 5′-triphosphate- 15N2, 13C (5-Methyl-CTP- 15N2, 13C) trisodium is the 15N and 13C labled 5-Methylcytidine 5′-triphosphate (HY-147338). 5-Methylcytidine 5′-triphosphate is a modified nucleoside triphosphate .
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-
-
- HY-W778154
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O,O-Dimethyl dithiophosphate- 13C2 (ammonium) is the 13C labeled isotope of O,O-Dimethyl dithiophosphate- 13C2 (ammonium) .
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-
- HY-W778148
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O,O-Diethyl dithiophosphate- 13C4 (ammonium) is the 13C labeled isotope of O,O-Diethyl dithiophosphate- 13C4 (ammonium) .
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-
- HY-W017049S
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Trifluoroacetic acid-13C2 sodium is the 13C labeled isotope of Sodium 2,2,2-trifluoroacetate (HY-W017049) .
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-
- HY-W754811
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Trifluoroacetic acid-13C sodium is the 13C labeled isotope of Trifluoroacetic acid-13C (sodium) (HY-W754811) .
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-
- HY-163992S
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VTMTRDTSISTAYMELSR-(Ile-13C6,15N) is the 13C and 15N labeled isotope of VTMTRDTSISTAYMELSR .
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-
-
- HY-163993S
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GMDRWGQGTLVTVSS-(Leu-13C6,15N) is the 13C and 15N labeled isotope of GMDRWGQGTLVTVSS .
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-
-
- HY-159191S
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VQPGQN(Phe- 13C9, 15N)HMFTKEKLEEVIKDI (TFA) is the 13C and 15N labeled isotope of VQPGQN-HMFTKEKLEEVIKDI (TFA) .
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-
-
- HY-W653989
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Desonide-13C3 is the 13C labeled isotope of Desonide-13C3 (HY-W653989) .
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-
-
- HY-W654120
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Creatine-13C3 is the 13C labeled isotope of Creatine-13C3 (HY-W654120) .
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-
- HY-W093399S
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Ammonium bicarbonate-15N is the 15N labeled isotope of Ammonium bicarbonate,AR,99% (HY-W093399). Ammonium bicarbonate is a bioactive chemical .
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-
-
- HY-W243408S
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Calcium carbonate-13C (Limestone-13C) is the 13C labeled isotope of Calcium carbonate,50nm (HY-W243408) .
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-
-
- HY-W770278
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Bisphenol Z-13C12 is the 13C labeled isotope of Bisphenol Z-13C12 (HY-W770278) .
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-
-
- HY-159192S
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SADDNIKTPAE(Arg- 13C6, 15N4)LLGPLPPSADDNLKT (TFA) is the 13C and 15N labeled isotope of SADDNIKTPAE-LLGPLPPSADDNLKT (TFA) .
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-
-
- HY-W654078
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Bisphenol AF- 13C12 is an isotopic label of Bisphenol AF. Bisphenol AF is used in polycarbonate plastic and epoxy resin manufacturing. Bisphenol AF can significantly increase intracellular ROS levels .
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-
-
- HY-W778140
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Diethyl phosphate- 13C4 (sodium) is the 13C labeled isotope of Diethyl phosphate- 13C4 (sodium)(HY-101417).Diethylphosphate (DEP) is product of metabolism and of environmental degradation of a commonly used insecticide Chlorpyrifos .
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-
-
- HY-129960S
-
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Selenocystine-77Se2 is a stable isotope labelled amino acid. L-Selenocystine is a diselenide-bridged amino acid. L-Selenocystine is a redox-active selenium compound that has both anti- and pro-oxidant actions.
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-
-
- HY-128393S1
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Trilinolein- 13C54 is the 13C-labeled Trilinolein (HY-128393). Radioactive isotopes labeled compounds can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified .
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-
-
- HY-18260S2
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Bisphenol A- 13C12 is the 13C-labeled Bisphenol A (HY-18260). Radioactive isotopes labeled compounds can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified .
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-
-
- HY-B2130S2
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Uric acid- 13C5 is the 13C-labeled Uric acid (HY-B2130). Radioactive isotopes labeled compounds can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified .
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-
-
- HY-W654157
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Dicloxacillin- 13C4 sodium hydrate is the 13C-labeled Dicloxacillin Sodium hydrate (HY-B0977). Radioactive isotopes labeled compounds can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified .
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-
-
- HY-W100312S
-
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o-Toluidine-13C6 hydrochloride (Toluene, 2-amino-13C6 hydrochloride) is the 13C labeled isotope of o-Toluidine hydrochloride (HY-W100312) .
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-
-
- HY-W585956
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Triclocarban-13C6 is the 13C labeled isotope of Triclocarban-13C6 (3,4,4′-Trichlorocarbanilide-13C6) .
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-
-
- HY-W768345
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D-(+)-Trehalose-13C12 is a 13C isotope labeled version of D-(+)-Trehalose (HY-N1132). D-(+)-Trehalose,which is widespread, can be used as a food ingredient and pharmaceutical excipient .
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-
-
- HY-N6726S1
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Fumonisin B3-13C34-1 is the isotopic internal standard of Fumonisin B3 (HY-N6726). Fumonisin B3 is a mycotoxin derived from fusarium fungi, a member of fumonisins .
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-
-
- HY-114293S
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Acetyl coenzyme A- 13C2 lithium is the 13C-labeled Acetyl coenzyme A (HY-114293). Radioactive isotopes labeled compounds can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified .
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-
-
- HY-W777581
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4-tert-Octylphenol-diethoxylate-13C6 is the 13C labeled isotope of 4-tert-Octylphenol-diethoxylate-13C6 (HY-W777581) .
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-
-
- HY-W777582
-
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4-tert-Octylphenol monoethoxylate-13C6 is the 13C labeled isotope of 4-tert-Octylphenol monoethoxylate-13C6 (HY-W777582) .
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-
-
- HY-W010575S
-
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(2R)-3-Amino-2-fluoropropanoic acid- 13C3 is a 13C-labeled (2R)-3-Amino-2-fluoropropanoic acid. (2R)-3-Amino-2-fluoropropanoic acid is the catabolism of anticancer agent 5-Fluorouracil[1].
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-
- HY-159193S
-
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DHATS(Leu- 13C6, 15N)PVTIPSAVST(Gly- 13C2, 15N)HTTPLPVTDT (TFA) is the 13C and 15N labeled isotope of DHATS-PVTIPSAVST-HTTPLPVTDT (TFA) .
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- HY-W779800
-
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D-α-Hydroxyglutaric acid- 13C5 disodium is the 13C-labeled D-α-Hydroxyglutaric acid (HY-113038). Radioactive isotopes labeled compounds can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified .
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- HY-143679S
-
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4-(3',6'-Dimethyl-3'-heptyl)phenol diethoxylate-13C6 is the 13C labeled isotope of 4-(3',6'-Dimethyl-3'-heptyl)phenol diethoxylate .
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- HY-W778207
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2'-Deoxyadenosine- 13C5 (monohydrate) is the 13C labeled isotope of 2'-Deoxyadenosine- 13C5 (monohydrate).2'-Deoxyadenosine monohydrate is a deoxyribonucleoside, a building block in chemical synthesis.2'-Deoxyadenosine monohydrate is a deoxyribonucleoside. A building block in the chemical synthesis.
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-
- HY-W749012
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(2,4,6-Trichlorophenoxy)acetic acid-13C6 is the 13C labeled isotope of (2,4,6-Trichlorophenoxy)acetic acid-13C6 (HY-W749012) .
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-
- HY-101399S
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γ-Glu-(Phe- 13C9, 15N) is the 13C and 15N labeled isotope of γ-Glu-Phe(HY-101399).γ-Glu-Phe or the postenzymatic reaction mixture enhanced the umami intensity of commercial soy sauce and model chicken soup.
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- HY-W778225
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Vanillic acid- 13C6 is the 13C labeled isotope of Vanillic acid- 13C6(HY-N0708 ).Vanillic acid is a flavoring agent found in edible plants and fruits, and in the root of angelica. Vanillic acid inhibits NF-κB activation. It has anti-inflammatory and antimicrobial activities.
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- HY-104026BS
-
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L-Kynurenine-13C10 (sulfate) is the 13C labeled L-Kynurenine sulfate. L-Kynurenine sulfate, an aryl hydrocarbon receptor (AHR) agonist that activates AHR-directed, naive T cell polarization to the anti-inflammatory Treg phenotype .
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- HY-104026CS
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L-Kynurenine- 13C10 (sulfate hemihydrate) is the 13C labeled L-Kynurenine sulfate. L-Kynurenine sulfate hemihydrate, an aryl hydrocarbon receptor (AHR) agonist that activates AHR-directed, naive T cell polarization to the anti-inflammatory Treg phenotype .
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- HY-159064S
-
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DSPSAPVNVT(Val- 13C5, 15)R TFA is the 13C and 15N-labeled DSPSAPVNVT(Val)R. Radioactive isotopes labeled compounds can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified .
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- HY-159065S
-
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FIQE(Val- 13C5, 15N)NTTTR TFA is the 13C and 15N-labeled FIQE(Val)NTTTR. Radioactive isotopes labeled compounds can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified .
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- HY-B0389A
-
Maximum Cited Publications
6 Publications Verification
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D-Glucose- 13C6 is a stable isotope-labeled counterpart of D-glucose (HY-B0389). D-Glucose- 13C6 can be used as a metabolic tracer to trace glucose-related synthetic catabolism or as synthesis ingredient, minimal media reagent, and internal standard .
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-
- HY-100196S1
-
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Pyrroloquinoline quinone-13C3 (sodium) is an isotope of Pyrroloquinoline quinone. Pyrroloquinoline quinone (PQQ), a redox co-factor, is an anionic, redox-cycling orthoquinone. Pyrroloquinoline quinone is isolated from cultures of methylotropic bacteria and tissues of mammals. Pyrroloquinoline quinone is an essential nutrient for mammals and is important for immune function .
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- HY-Y0264S
-
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4-Hydroxybenzoic acid- 13C6 is the 13C labeled isotope of 4-Hydroxybenzoic acid- 13C6.4-Hydroxybenzoic acid is a phenolic derivative of benzoic acid, which can inhibit most Gram-positive bacteria and some Gram-negative bacteria with an IC50 value of 160 μg/mL.
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- HY-W654362
-
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(R)-2-Thioxothiazolidine-4-carboxylic acid- 13C3 is the 13C-labeled (R)-2-Thioxothiazolidine-4-carboxylic acid. Radioactive isotopes labeled compounds can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified .
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-
- HY-B1204S2
-
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Histamine- 13C5, 15N3 (Ergamine- 13C5, 15N3) is the 13C and 15N labeled isotope of Histamine (HY-B1204). Histamine is an organic nitrogen compound that participates in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter .
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-
- HY-W106014S
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[1,1'-Biphenyl]-3-amine-13C6 hydrochloride (Biphenyl-3-amine-13C6 hydrochloride) is the 13C labeled isotope of [1,1'-Biphenyl]-3-amine hydrochloride (HY-W106014) .
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- HY-W777583
-
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2-[4-(1-Ethyl-1,4-dimethylpentyl)phenoxy]ethanol-13C6 is the 13C labeled isotope of 2-[4-(1-Ethyl-1,4-dimethylpentyl)phenoxy]ethanol-13C6 (HY-W777583) .
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-
- HY-W712567
-
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Adenine-15N5 hydrochloride (6-Aminopurine-15N5 hydrochloride) is the 15N labeled isotope of Adenine-15N5 hydrochloride (6-Aminopurine-15N5 hydrochloride; Vitamin B4-15N5 hydrochloride) .
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- HY-W769714
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Favipiravir- 13C3 is the 13C labeled isotope of Favipiravir- 13C3(HY-14768 ).Favipiravir (T-705) is a potent viral RNA polymerase inhibitor, it is phosphoribosylated by cellular enzymes to its active form, Favipiravir-ribofuranosyl-5′-triphosphate (RTP). Favipiravir-RTP inhibits the influenza viral RNA-dependent RNA polymerase (RdRP) activity with an IC50 of 341 nM.
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- HY-P1033S1
-
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[Pyr1]-Apelin-13, Pro( 13C5, 15N) (TFA) is the 13C and 15N labeled isotope of [Pyr1]-Apelin-13(HY-P1033).[Pyr1]-Apelin-13 is a potent and selective endogenous apelin receptor agonist .
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- HY-W749209
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Sodium Acetate-1,2-13C2 is a stable isotope labeled compound with biomarker and metabolic tracking activity. Sodium Acetate-1,2-13C2 is often used in biochemical research for the analysis of metabolic pathways. Sodium Acetate-1,2-13C2 is also used in medical imaging and compound development to improve the understanding of biological processes.
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-
- HY-W750600
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Acetonitrile-15N (Methyl cyanide-15N) is a stable isotope labeled organic compound with important applications in metabolic research and molecular labeling. Acetonitrile-15N is used in biolabeling experiments to track metabolic pathways and help understand the chemical reaction mechanisms in organisms. Acetonitrile-15N is also widely used in environmental science to study the migration and transformation processes of pollutants.
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- HY-106950S1
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Fosfructose- 13C6 (tetrasodium hydrate) is the 13C labeled Fosfructose (HY-106950). Fosfructose is a cytoprotective natural sugar phosphate for the potential treatment of cardiovascular ischemia, sickle cell anemia and asthma[1].
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- HY-W009538S1
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5-Fluoro-5'-deoxycytidine-13C5 is the 13C labeled isotope of 5-Fluoro-5'-deoxycytidine (HY-W009538). 5-Fluoro-5'-deoxycytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
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- HY-B0122S
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Topiramate-13C6 (McN 4853-13C6) is the 13C labeled isotope of Topiramate (HY-B0122). Topiramate (McN 4853) is a broad-spectrum antiepileptic agent. Topiramate is a GluR5 receptor antagonist. Topiramate produces its antiepileptic effects through enhancement of GABAergic activity, inhibition of kainate/AMPA receptors, inhibition of voltage-sensitive sodium and calcium channels, increases in potassium conductance, and inhibition of carbonic anhydrase .
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- HY-B0101S1
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Fluconazole-13C2,15N (UK-49858-13C2,15N) is the 13C and 15N labeled isotope of Fluconazole (HY-B0101). Fluconazole (UK-49858) is a triazole antifungal agent with excellent activities against a broad range of fungi, especially against Candida albicans. Fluconazole inhibits C. albicans and Candida kefyr with IC99s range from 0.20 μg/mL to 0.39 μg/mL .
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- HY-W750796
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Butyric acid-13C4 sodium (Butanoic acid-13C4 sodium) is a stable isotope labeled compound with the activity of promoting cell proliferation and regulating gene expression. Butyric acid-13C4 sodium can be used in metabolic research and compound development to help scientists gain a deeper understanding of the role of short-chain fatty acids in organisms. Butyric acid-13C4 sodium also plays an important role in nutrition and intestinal health research, especially in the regulation of probiotic function and intestinal microbiota.
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- HY-10020S
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Varenicline-15N3 Hydrochloride (CP 526555-15N3 Hydrochloride) is the 15N labeled isotope of Varenicline hydrochloride (HY-10020). Varenicline (CP 526555) is an orally active partial agonist of α4β2 nicotinic acetylcholine receptor (α4β2 nAChR, IC50 = 250 nM), which is the principal mediator of nicotine dependence. Varenicline is also a partial agonist of α6β2 nAChR and a full agonist of α6β2 nAChR. Varenicline blocks the direct agonist effects of nicotine on nAChR while stimulates nAChR in a more moderate way, being widely used as an aid of smoking cessation .
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- HY-14605BS
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Rasagiline- 13C3 (mesylate racemic) is a 13C-labeled Rasagiline mesylate racemic. Rasagiline mesylate racemic is a highly potent selective irreversible mitochondrial monoamine oxidase (MAO) inhibitor[1]. Rasagiline-13C3 (mesylate racemic) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-141905S
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Isophorone Diamine- 13C, 15N2 is the 13C and 15N labeled Isophorone Diamine[1].
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- HY-N0216S1
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Benzoic acid- 13C6 is the 13C-labeled Benzoic acid. Benzoic acid is an aromatic alcohol existing naturally in many plants and is a common additive to food, drinks, cosmetics and other products. It acts as preservatives through inhibiting both bacteria and fungi.
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- HY-B2219S2
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Stearic acid- 13C18is the 13C-labeled Stearic acid. Stearic acid is a long chain dietary saturated fatty acid which exists in many animal and vegetable fats and oils.
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- HY-N0683S
-
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α-Vitamin E- 13C6 is the 13C-labeled α-Vitamin E. α-Vitamin E ((+)-α-Tocopherol), a naturally occurring vitamin E form, is a potent antioxidant[1][2].
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- HY-W020044S
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DL-alpha-Tocopherol- 13C3 is the 13C-labeled DL-alpha-Tocopherol. DL-alpha-Tocopherol is a synthetic vitamin E, with antioxidation effect. DL-alpha-Tocopherol protects human skin fibroblasts against the cytotoxic effect of UVB[1].
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- HY-141919S
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1-Bromo-4-iodobenzene- 13C6 is the 13C labeled 1-Bromo-4-iodobenzene[1].
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- HY-B2130S
-
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Uric acid- 13C, 15N3 is the 13C-labeled and 15N-labeled Uric acid. Uric acid, scavenger of oxygen radical, is a very important antioxidant that help maintains the stability of blood pressure and antioxidant stress. Uric acid can remove reactive oxygen species (ROS) such as singlet oxygen and peroxynitrite, inhibiting lipid peroxidation[1][2].
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- HY-W141978S
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DL-Lysine2- 15N (dihydrochloride) is the 15N labeled DL-Lysine2 dihydrochloride[1].
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- HY-N0390S1
-
1 Publications Verification
|
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L-Glutamine- 13C5 is the 13C-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells[1][2].
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- HY-W009204S3
-
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Fmoc-Ala-OH-3- 13C is the 13C labeled Fmoc-Ala-OH[1].
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- HY-W017443S
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L-Asparagine- 13C4, 15N2 (monohydrate)is the 13C-labeled and 15N-labeled L-Asparagine monohydrate. L-Asparagine monohydrate ((-)-Asparagine monohydrate) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue.
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-
- HY-Y1250S1
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Fmoc-Gly-OH-2- 13C, 15N is the 13C, 15N labeled Fmoc-Gly-OH-2[1].
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-
- HY-B0456S1
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Riboflavin-5-Phosphate- 13C4, 15N2-1 is the 13C-labeled and 15N-labeled Riboflavin. Riboflavin is an easily absorbed micronutrient with a key role in maintaining health in humans and other animals.
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-
- HY-90006S2
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5-Fluorouracil- 15N2 is the 15N-labeled 5-Fluorouracil. 5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer[1][2]. 5-Fluorouracil also inhibits HIV[3].
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- HY-N0390S
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L-Glutamine- 15N is the 15N-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells[1][2].
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- HY-A0161S
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Chlophedianol- 13C6 is the 13C labeled Chlophedianol (HY-A0161). Chlophedianol is an orally active and potent antitussive agent. Chlophedianol can be used for the research of acute cough due to upper respiratory tract infections (URIs)[1][2][3].
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-
- HY-Y0978S
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Boc-Glycine- 15N is the 15N labeled Boc-Glycine[1].
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-
- HY-Y0677S
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Carbethoxymethyldiethyl phosphonate- 13C2 is the C13 labeled Carbethoxymethyldiethyl phosphonate[1].
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-
- HY-32351AS1
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Calcifediol- 13C5 monohydrate is the 13C-labeled Calcifediol monohydrate. Calcifediol monohydrate (25-hydroxy Vitamin D3 monohydrate), is an effective VDR ligand and VD supplement. Calcifediol is a prohormone of the vitamin D endocrine system (VDES) and is hydroxylated in the liver to produce the active form, calcitriol. Calcifediol can rapidly increase serum VD levels .
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-
- HY-W009204S
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Fmoc-Ala-OH- 15N is the 15N labeled Fmoc-Ala-OH[1].
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-
- HY-Y0252S
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L-Proline- 13C5 is the 13C-labeled L-Proline. L-Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins.
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-
- HY-N0382S
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Galangin- 13C3 is the 13C-labeled Galangin. Galangin (Norizalpinin) is an agonist/antagonist of the arylhydrocarbon receptor. Galangin (Norizalpinin) also shows inhibition of CYP1A1 activity.
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-
- HY-W104010S
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2-Chloroaniline hydrochloride- 13C6 is the 13C labeled 2-Chloroaniline hydrochloride[1].
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-
- HY-W001138S
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4-Bromobenzaldehyde- 13C6 is the 13C labeled 4-Bromobenzaldehyde[1].
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-
- HY-W104549S
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3,6-Dichloro-2-hydroxybenzoic acid- 13C6 is the 13C labeled 3,6-Dichloro-2-hydroxybenzoic acid[1].
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- HY-W040047S
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Pregnanediol 3-glucuronide- 13C5 is 13C-labeled Pregnanediol (HY-107850) Pregnanediol is the major metabolite of progesterone and can be excreted via urine. Pregnanediol offers an indirect way to measure progesterone levels in vivo.
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- HY-N0001S
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(±)-Epicatechin- 13C3 is the 13C labeled (±)-Epicatechin. (-)-Epicatechin (HY-N0001) inhibits cyclooxygenase-1 (COX-1) with an IC50 of 3.2 μM. (-)-Epicatechin inhibits the IL-1β-induced expression of iNOS by blocking the nuclear localization of the p65 subunit of NF-κB[1].
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-
- HY-34428S
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4-Fluorobenzonitrile- 13C6 is the 13C labeled 4-Fluorobenzonitrile[1].
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-
- HY-B0234S
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Estrone- 13C3 is the 13C-labeled Estrone. Estrone (E1) is a natural estrogenic hormone. Estrone is the main representative of the endogenous estrogens and is produced by several tissues, especially adipose tissue. Estrone is the result of the process of aromatization of androstenedione that occurs in fat cells[1][2].
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-
- HY-B0451AS5
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Dopamine- 13C (hydrochloride) is the 13C labeled Dopamine hydrochloride (ASL279)[1].
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-
- HY-130585S
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Estradiol undecylate- 13C3 is the 13C labeled Estradiol undecylate[1].
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-
- HY-N0437S2
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Progesterone- 13C3 is the 13C-labeled Progesterone. Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy.
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-
- HY-B0318S
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Metronidazole- 13C2, 15N2 is the 13C-labeled and 15N-labeled Metronidazole. Metronidazole is a nitroimidazole antibiotic medication used particularly for anaerobic bacteria and protozoa.
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-
- HY-Y0479S3
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L-Lactic acid-2- 13C1 is the 13C-labeled L-Lactic acid (HY-Y0479). L-Lactic acid is a buildiing block which can be used as a precursor for the production of the bioplastic polymer poly-lactic acid .
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- HY-Z0283S
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Benzamide- 15N is a 15N-labeled Benzamide. Benzamide inhibits poly(ADP-ribose) polymerase (PARP)[1][2].
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-
- HY-18085S2
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Quercetin- 13C3 is the 13C-labeled Quercetin. Quercetin, a natural flavonoid, is a stimulator of recombinant SIRT1 and also a PI3K inhibitor with IC50 of 2.4 μM, 3.0 μM and 5.4 μM for PI3K γ, PI3K δ and PI3K β, respectively[1].
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-
- HY-W015824S3
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DL-Aspartic acid- 13C1 is the 13C labeled DL-Aspartic acid[1].
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-
- HY-13653S
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(+/-)-Epigallocatechin Gallate- 13C3 is the 13C-labeled (-)-Epigallocatechin Gallate. (-)-Epigallocatechin Gallate is a tea flavonoid with potent antioxidant, antiinflammatory, and anticarcinogenic properties. (-)-Epigallocatechin Gallate is reported to inhibit EGFR signaling and thereby exert anticancer effects[1]. (-)-Epigallocatechin Gallate (EGCG) is a glutamate dehydrogenase 1/2 (GDH1/2, GLUD1/2) inhibitor. Epigallocatechin-3-gallate induces oxidative phosphorylation (OXPHOS) by activating cytochrome c oxidase.
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-
- HY-15037S
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Diclofenac- 13C6 (sodium heminonahydrate) is the 13C-labeled Diclofenac Sodium. Diclofenac Sodium (GP 45840) is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells[1], and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively[2]. Diclofenac Sodium induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade[3].
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-
- HY-B0843S
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Metalaxyl- 13C6 is the 13C-labeled Metalaxyl. Metalaxyl is a fungicide that inhibits protein synthesis in fungi. Metalaxyl inhibits the growth of potato blight (P. infestans) fungal isolates from Serbian potato fields (EC50s=0.3-3.9 μg/mL).
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-
- HY-Y0289S
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1-Dodecanol- 13C is the 13C-labeled 1-Dodecanol. 1-Dodecanol is an endogenous metabolite.
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-
- HY-W016498S1
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Paraxanthine- 13C4, 15N3 is the 13C-labeled and 15N-labeled Paraxanthine. Paraxanthine, a caffeine metabolite, provides protection against Dopaminergic cell death via stimulation of Ryanodine Receptor Channels.
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-
- HY-N8847S
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α-Ionone- 13C3 is the 13C labeled α-Ionone[1].
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-
- HY-Y0842S
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Formamide- 13C is the 13C-labeled Formamide. Formamide is an amide derived from formic acid and has been used as solvent for many ionic compounds.
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-
- HY-Y0946S
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Acetamide- 15N is the 15N-labeled Acetamide. Acetamide is used as an intermediate in the synthesis of methylamine, thioacetamide, and insecticides, and as a plasticizer in leather, cloth and coatings. Acetamide has carcinogenicity[1][2].
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-
- HY-B0289S
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Erdosteine- 13C4 is a 13C-labeled Erdosteine. Erdosteine inhibits lipopolysaccharide (LPS)-induced NF-κB activation[1][2]. Erdosteine has muco-modulatory, anti-bacterial, anti-inflammatory and anti-oxidant effects[3].
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-
- HY-N0215S2
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L-Phenylalanine- 13C is the 13C-labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4].
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-
- HY-W014632S
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4-Trifluoromethylsalicylic acid- 13C6 is the 13C labeled 4-Trifluoromethylsalicylic acid[1]. 4-Trifluoromethylsalicylic acid is a platelet aggregation inhibitor[2].
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-
- HY-W015913S
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Sodium 2-oxopropanoate- 13C3 is the 13C-labeled Sodium 2-oxopropanoate. Sodium 2-oxopropanoate (Sodium pyruvate), a three-carbon metabolite of Glucose, is a compound produced in the glycolytic pathway. Sodium 2-oxopropanoate is a free radical scavenger that can scavenge ROS[1][2].
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- HY-B0401S1
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Tolbutamide- 13C is the 13C-labeled Tolbutamide. Tolbutamide is a first generation potassium channel blocker, sulfonylurea oral hypoglycemic agent.
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- HY-B2033S
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Pyrimethanil- 13C, 15N2 is the 13C-labeled and 15N-labeled Pyrimethanil. Pyrimethanil is an anilinopyrimidine and broad-spectrum contact fungicide for the control of Botrytis spp. on a wide variety of crops[1]. Pyrimethanil inhibits the biosynthesis of methionine and other amino acids in Botrytis cinerea. Pyrimethanil can be used for the research of fungal diseases prevention on fruit, vegetable and ornamental plants with mold infection[3].
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- HY-B0178AS
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Guanidine- 13C, 15N3 (hydrochloride)is the 13C-labeled and 15N-labeled Guanidine hydrochloride. Guanidine hydrochloride (Guanidinium chloride) a strong chaotrope, is also a strong denaturant of proteins[1][2].
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- HY-N0486S2
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Leucine- 13C6 is the 13C-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway[1].
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- HY-N0830S6
-
3 Publications Verification
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Palmitic acid- 13C16 is the 13C-labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. PA can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells[1][2].
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- HY-115584S
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Lufenuron- 13C6 is a 13C-labeled Lufenuron. Lufenuron is a lipophilic benzoylurea insecticide and a chitin synthesis inhibitor that can used for flea and fish lice control. Lufenuron inhibits moulting of arthropods[1][2].
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- HY-N0216S2
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Benzoic acid- 13C is the 13C-labeled Benzoic acid. Benzoic acid is an aromatic alcohol existing naturally in many plants and is a common additive to food, drinks, cosmetics and other products. It acts as preservatives through inhibiting both bacteria and fungi.
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-
- HY-16561S1
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Resveratrol- 13C6 is the 13C-labeled Resveratrol. Resveratrol (trans-Resveratrol; SRT501), a natural polyphenolic phytoalexin that possesses anti-oxidant, anti-inflammatory, cardioprotective, and anti-cancer properties. Resveratrol (SRT 501) has a wide spectrum of targets including mTOR, JAK, β-amyloid, Adenylyl cyclase, IKKβ, DNA polymerase. Resveratrol also is a specific SIRT1 activator[1][2][3][4]. Resveratrol is a potent pregnane X receptor (PXR) inhibitor[5]. Resveratrol is an Nrf2 activator, ameliorates aging-related progressive renal injury in mice model[6]. Resveratrol increases production of NO in endothelial cells[7].
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- HY-N0667S4
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L-Asparagine-4- 13C (monohydrate) is the 13C-labeled L-Asparagine. L-Asparagine ((-)-Asparagine) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue.
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-
- HY-B0451AS6
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Dopamine- 13C, 15N (hydrochloride) is the 13C and 15N labeled Dopamine hydrochloride[1].
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-
- HY-N1981S
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Triolein- 13C3 is the 13C-labeled Triolein. Triolein is a symmetrical triacylglycerol, reduces MMP-1 upregulation, with strong antioxidant and anti-inflammatory properties[1].
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- HY-N0322S4
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Cholesterol- 13C3 is the 13C-labeled Cholesterol. Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins . Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist .
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- HY-N0666S
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L-Aspartic acid- 13C is a 13C labeled L-Aspartic acid. L-Aspartic acid is is an amino acid, shown to be a suitable proagent for colon-specific agent deliverly[1][2].
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- HY-B0859S
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MCPA- 13C8 is the 13C-labeled MCPA. MCPA is a phenoxy herbicide, and widely used to control annual and perennial broad leaved weeds, including poppy, thistles and docks, in crops such as cereals, rice, linseed, flax, grassland and turf[1][2].
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- HY-141913S
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3-Chlorotyrosine- 13C9, 15N (hydrochloride) is the 13C and 15N labeled 3-Chlorotyrosine[1].
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-
- HY-141925S
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3-Octanone- 13C is the 13C labeled 3-Octanone[1].
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-
- HY-B0434S
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Ribavirin- 13C5 is the 13C-labeled Ribavirin. Ribavirin (ICN-1229) is an antiviral agent against a broad spectrum of viruses including HCV, HIVl, and RSV.
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- HY-B1776AS1
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1 Publications Verification
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Spermidine- 13C4 (hydrochloride) is the 13C-labeled Spermidine trihydrochloride. Spermidine hydrochloride maintains cell membrane stability, increases antioxidant enzymes activities, improving photosystem II (PSII), and relevant gene expression. Spermidine hydrochloride significantly decreases the H2O2 and O2.- contents[1].
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- HY-W013677S
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4-Fluorobenzoic acid- 13C6 is the 13C labeled 4-Fluorobenzoic acid[1].
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- HY-15097S
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Myricetin- 13C3 is the 13C-labeled Myricetin. Myricetin is a common plant-derived flavonoid with a wide range of activities including strong anti-oxidant, anticancer, antidiabetic and anti-inflammatory activities.
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- HY-14608S
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L-Glutamic acid- 13C is the 13C-labeled L-Glutamic acid. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals.
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-
- HY-141909S
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4-Fluoroiodobenzene- 13C6 is the 13C labeled 4-Fluoroiodobenzene[1].
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-
- HY-17383S
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Levomefolate- 13C5 (calcium) is the 13C-labeled Levomefolate (calcium). Levomefolate calcium is an artificial form of folate.
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- HY-B1732S
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DL-3-Phenylalanine- 15N is the 15N labeled DL-3-Phenylalanine[1].
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- HY-B2156S1
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Menaquinone-4- 13C6 is the 13C-labeled Menaquinone-4. Menaquinone-4 is a vitamin K, used as a hemostatic agent, and also a adjunctive therapy for the pain of osteoporosis.
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- HY-W008371S
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Fmoc-Met-OH- 15N is the 15N labeled Fmoc-Met-OH[1].
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- HY-141929S
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β-aminomethyl-L-alanine- 13C, 15N2 (dihydrochloride) is the 13C and 15N labeled β-aminomethyl-L-alanine[1].
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- HY-Y1117S
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Melamine- 15N3 is a 15N-labeled Melamine. Melamine is a metabolite of cyromazine. Melamine is a intermediate for the synthesis of melamine resin and plastic materials[1].
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- HY-139145S
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Etbicyphat- 13C3 is the 13C labeled Etbicyphat (HY-139145). Etbicyphat is a potent GABA(A) receptors competitive antagonist. Etbicyphat induces epileptiform activities in hippocampal CA1 neurons, and binds to the GABA(A)-benzodiazepine receptors[1][2].
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- HY-W012530S
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Phenylpyruvic acid- 13C6 sodium is the 13C-labeled Phenylpyruvic acid. Phenylpyruvic acid is used in the synthesis of 3-phenyllactic acid (PLA) by lactate dehydrogenase .
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- HY-113118S
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Acetylamino-6-amino-3-methyluracil- 13C4, 15N3 is the 13C and 15N labeled Acetylamino-6-amino-3-methyluracil[1].
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- HY-116084S1
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Trimethylamine-N-oxide- 13C3 is the 13C-labeled Trimethylamine N-oxide. Trimethylamine N-oxide is a gut microbe-dependent metabolite of dietary choline and other trimethylamine-containing nutrients. Trimethylamine N-oxide induces inflammation by activating the ROS/NLRP3 inflammasome. Trimethylamine N-oxide also accelerates fibroblast-myofibroblast differentiation and induces cardiac fibrosis by activating the TGF-β/smad2 signaling pathway[1][2][3].
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- HY-19821S
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Fmoc-Ile-OH- 15N is the 15N labeled Fmoc-Ile-OH[1].
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- HY-113294S
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3-Hydroxykynurenine- 13C3, 15N (3-Hydroxy-DL-kynurenine- 13C3, 15N) is the 13C and 15N labeled 3-Hydroxykynurenine (HY-113294) . 3-Hydroxykynurenine, a metabolite of tryptophan, is a potential endogenous neurotoxin whose increased levels have been described in several neurodegenerative disorders. 3-Hydroxykynurenine induces neuronal apoptosis .
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- HY-41877S
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Succinimide- 15N is the 15N labeled Succinimide [1].
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- HY-13632S1
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Exemestane- 13C3 is the 13C-labeled Exemestane. Exemestane (FCE 24304) is a selective, irreversible and orally active steroidal aromatase inhibitor with IC50s of 30 nM and 40 nM for human placental and rat ovarian aromatase, respectively. Exemestane can be used for hormone-dependent breast cancer research[1][2].
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- HY-N0470S
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L-Lysine- 15N2 (hydrochloride) is the 15N-labeled L-Lysine hydrochloride. L-lysine hydrochloride is an essential amino acid for humans with various benefits including treating herpes, increasing calcium absorption, reducing diabetes-related illnesses and improving gut health.
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- HY-N1428S1
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Citric acid- 13C6 is the 13C-labeled Citric acid. Citric acid is a weak organic tricarboxylic acid found in citrus fruits. Citric acid is a natural preservative and food tartness enhancer.
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- HY-B1395S1
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Mecamylamine (hydrochloride)- 13C4, 15N is the 13C-labeled and 15N-labeled Mecamylamine hydrochloride. Mecamylamine hydrochloride is an orally active, nonselective, noncompetitive nAChR antagonist that can treat various neuropsychiatric disorders. Mecamylamine hydrochloride is originally used as a ganglionic blocker in treating hypertension. Mecamylamine hydrochloride can easily crosses the blood-brain barrier[1][2].
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- HY-N0521AS
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(+)-Gallocatechin- 13C3 is the 13C-labeled (+)-Gallocatechin. (+)-Gallocatechin is a polyphenol compound from green tea, possesses anticancer activity[1].
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-
- HY-W010696AS
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Reverse T3- 13C6 (hydrochloride) is the 13C labeled Reverse T3[1].
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-
- HY-141917S
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3-Methyluric Acid- 13C4, 15N3 is the 13C and 15N labeled 3-Methyluric Acid[1].
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-
- HY-W007318S
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2-Iodoaniline- 13C6 is the 13C labeled 2-Iodoaniline[1].
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-
- HY-W015084S
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β-Ionone- 13C3 is the 13C-labeled β-Ionone. β-Ionone is effective in the induction of apoptosis in gastric adenocarcinoma SGC7901 cells. Anti-cancer activity[1].
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- HY-N0455AS
-
1 Publications Verification
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L-Arginine- 15N2 (hydrochloride) is the 15N-labeled L-Arginine (hydrochloride). L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.
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-
- HY-W099580S
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Hexadecane-1,2- 13C2 is the 13C labeled Hexadecane[1].
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-
- HY-W010407S
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Cyanuric acid- 13C3 is the 13C labeled Cyanuric acid[1].
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- HY-N1394S
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p-Anisic acid- 13C6 is the 13C-labeled p-Anisic acid. p-Anisic acid (4-Methoxybenzoic acid) is one of the isomers of anisic acid, with anti-bacterial and antiseptic properties[1].
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- HY-W015883S
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Fumaric acid- 13C4 is the 13C-labeled Fumaric acid. Fumaric acid, associated with fumarase deficiency, is identified as an oncometabolite or an endogenous, cancer causing metabolite.
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- HY-N0229S1
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L-Alanine-1- 13C is the 13C-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.
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-
- HY-14608S1
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L-Glutamic acid-1- 13C is the 13C-labeled L-Glutamic acid. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals.
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-
- HY-16271S
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Kevetrin (hydrochloride)- 13C2, 15N3 is the 13C-labeled and 15N-labeled Kevetrin (hydrochloride). Kevetrin hydrochloride is a small molecule and activator of the tumor suppressor protein p53, with potential antineoplastic activity.
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-
- HY-W013495S
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Porphobilinogen- 13C2 is the 13C-labeled Porphobilinogen. Porphobilinogen could act as a phototoxin, a neurotoxin, and a metabotoxin.
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- HY-W006057AS1
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Sodium 3-methyl-2-oxobutanoate-d hydrate is the deuterium labeled Sodium 3-methyl-2-oxobutanoate. Sodium 3-methyl-2-oxobutanoate is a precursor of pantothenic acid in Escherichia coli[1][2][3].
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-
- HY-141928S
-
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4-Bromoanisole- 13C6 is the 13C labeled 4-Bromoanisole[1].
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- HY-B0337S2
-
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|
|
Sulfadimethoxine- 13C6 is the 13C-labeled Sulfadimethoxine. Sulfadimethoxine (Sulphadimethoxine) is a sulfonamide antibiotic used to treat many infections[1][2].
|
-
- HY-B0388S
-
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|
|
Probucol- 13C3 is the 13C-labeled Probucol. Probucol (DH-581) is an anti-hyperlipidemic agent by lowering the level of cholesterol in the bloodstream by increasing the rate of LDL catabolism.
|
-
- HY-N0356S
-
|
|
|
(+/-)-Catechin Gallate- 13C3 is the 13C-labeled (-)-Catechin gallate. (-)-Catechin gallate is a minor constituent in green tea catechins. (-)-Catechin gallate inhibits the activity of COX-1 and COX-2 enzymes.
|
-
- HY-B0504S1
-
|
|
|
Creatinine- 13C is the 13C-labeled Creatinine. Creatinine (NSC13123) is a break-down product of creatine phosphate in muscle, and is usually produced at a fairly constant rate by the body.
|
-
- HY-W012566S
-
|
|
|
Naphthalene-1,5-diamine- 15N2 is the 15N labeled Naphthalene-1,5-diamine[1].
|
-
- HY-B0412S3
-
|
|
|
Estriol- 13C3 is the 13C-labeled Estriol. Estriol is an antagonist of the G-protein coupled estrogen receptor in estrogen receptor-negative breast cancer cells.
|
-
- HY-18572S
-
|
|
|
2,4-D- 13C6 is the 13C-labeled 2,4-D. 2,4-D (2,4-Dichlorophenoxyacetic acid) is a selective systemic herbicide for the control of broad-leaved weeds. 2,4-D acts as a plant hormone, causing uncontrolled growth in the meristematic tissues. 2,4-D inhibits DNA and protein synthesis and thereby prevents normal plant growth and development[1].
|
-
- HY-16938S
-
|
|
|
5'-Methylthioadenosine- 13C6 is the 13C-labeled 5'-Methylthioadenosine. 5'-Methylthioadenosine (5'-(Methylthio)-5'-deoxyadenosine) is a nucleoside generated from S-adenosylmethionine (SAM) during polyamine synthesis[1]. 5'-Methylthioadenosine suppresses tumors by inhibiting tumor cell proliferation, invasion, and the induction of apoptosis while controlling the inflammatory micro-environments of tumor tissue. 5'-Methylthioadenosine and its associated materials have striking regulatory effects on tumorigenesis[2].
|
-
- HY-B0150S1
-
|
|
|
Nicotinamide- 15N, 13C3 is the 13C-labeled and 15N-labeled Nicotinamide. Nicotinamide is a form of vitamin B3 that plays essential roles in cell physiology through facilitating NAD+ redox homeostasis and providing NAD+ as a substrate to a class of enzymes that catalyze non-redox reactions. Nicotinamide is an inhibitor of SIRT1.
|
-
- HY-Y0989S2
-
|
|
|
Acetophenone-1,2- 13C2 is the 13C-labeled Acetophenone. Acetophenone is an organic compound with simple structure[1].
|
-
- HY-W014993S
-
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|
|
1,3-Dimethyluric acid- 13C4, 15N3 is the 13C-labeled and 15N-labeled 1,3-Dimethyluric acid. 1,3-Dimethyluric acid is a product of theophylline metabolism in man. 1,3-Dimethyluric acid is one of the purine components in urinary calculi.
|
-
- HY-N7091S
-
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|
|
Atrazine- 15N is the 15N-labeled Atrazine. Atrazine is principally used for control of certain annual broadleaf and grass weeds. Atrazine inhibits photophosphorylation but typically does not result in lethality or permanent cell damage in the short term[1].
|
-
- HY-B1337S4
-
|
|
|
Choline Chloride- 13C3 is the 13C-labeled Choline (chloride). Choline chloride is an organic compound and a quaternary ammonium salt, an acyl group acceptor and choline acetyltransferase substrate, also is an important additive in feed especially for chickens where it accelerates growth.
|
-
- HY-Y1088S
-
|
|
|
Hydrocinnamic acid-2,3- 13C2 is the 13C-labeled Hydrocinnamic acid. Hydrocinnamic acid is the major rhizospheric compound with known growth regulatory activities.
|
-
- HY-B1456AS
-
|
|
|
Fenoprofen- 13C6 (sodium hydrate) is the 13C labeled Fenoprofen (HY-B1456A). Fenoprofen is a nonsteroidal anti-inflammatory agent (NSAID). Fenoprofen can be used to to relieve symptoms of arthritis (osteoarthritis and rheumatoid arthritis), such as inflammation, swelling, stiffness, and joint pain. Fenoprofen is an allosteric enhancer for melanocortin receptors. Fenoprofen also increases ERK1/2 activation[1][2][3].
|
-
- HY-N0305S
-
|
|
|
5-Aminolevulinic acid- 15N (hydrochloride) is the 15N-labeled 5-Aminolevulinic acid (hydrochloride). 5-Aminolevulinic acid hydrochloride (5-ALA hydrochloride) is an intermediate in heme biosynthesis in the body and the universal precursor of tetrapyrroles.
|
-
- HY-W091039S
-
|
|
|
N-Acetyl-α-neuraminic acid- 13C3 is the 13C labeled N-Acetyl-α-neuraminic acid[1].
|
-
- HY-B0891S1
-
|
|
|
17α-Hydroxyprogesterone- 13C3 is the 13C-labeled 17α-Hydroxyprogesterone. 17α-Hydroxyprogesterone (17-Hydroxyprogesterone) is an endogenous progestogen as well as chemical intermediate in the biosynthesis of other steroid hormones, including the corticosteroids and the androgens and the estrogens.
|
-
- HY-N0351S
-
|
|
|
p-Coumaric acid- 13C3 is the 13C-labeled p-Coumaric acid. p-Coumaric acid is the abundant isomer of cinnamic acid which has antitumor and anti-mutagenic activities.
|
-
- HY-141939S
-
|
|
|
Triiodothyronine- 13C6 (hydrochloride) is the 13C labeled Triiodothyronine[1].
|
-
- HY-N0473S1
-
|
|
|
L-Tyrosine- 15N is the 15N-labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.
|
-
- HY-Y1250S
-
|
|
|
Fmoc-Gly-OH- 15N is the 15N labeled Fmoc-Gly-OH[1].
|
-
- HY-N6618S
-
|
|
|
DL-Mannitol- 13C is the 13C-labeled DL-Mannitol. DL-Mannitol is obtained by combining D-mannitol with a sample of Lmannitol obtained by reduction of L-mannono-1, Clactone[1].
|
-
- HY-Y0931S
-
|
|
|
3-Iodobenzoic Acid- 13C6 is the 13C labeled 3-Iodobenzoic Acid[1].
|
-
- HY-66005S3
-
|
|
|
Acetaminophen-13C6 (Paracetamol-13C6) is the 13C-labeled Acetaminophen. Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM; is a widely used antipyretic and analgesic agent . Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor .
|
-
- HY-W008449S1
-
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|
|
1-Methylxanthine- 13C4, 15N3 is the 13C-labeled and 15N-labeled 1-Methylxanthine. 1-Methylxanthine, a caffeine derivative, is an essential human urinary metabolite of caffeine and theophylline (1,3-dimethylxanthine, TP)[1]. 1-Methylxanthine enhances the radiosensitivity of tumor cells[2].
|
-
- HY-W015824S2
-
|
|
|
DL-Aspartic acid-3- 13C is the 13C labeled DL-Aspartic acid[1].
|
-
- HY-16637S3
-
|
|
|
Folic acid- 13C5 is the 13C-labeled Folic acid. Folic acid (Vitamin M; Vitamin B9) is a B vitamin; is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis.
|
-
- HY-Y1027S1
-
|
|
|
2-Chlorobenzoic acid- 13C6 is the 13C labeled 2-Chlorobenzoic acid[1].
|
-
- HY-N0486S1
-
|
|
|
L-Leucine- 13C is the 13C-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway[1].
|
-
- HY-N1393S
-
|
|
|
2-Methoxybenzoic acid- 13C6 is the 13C-labeled 2-Methoxybenzoic acid. 2-Methoxybenzoic acid (NSC 3778) is used as an internal standard of salicylic acid and its putative biosynthetic precursors in cucumber leaves. Another known use is in the synthesis of Benextramine.
|
-
- HY-B0456S
-
|
|
|
Riboflavin- 13C4, 15N2is the 13C-labeled and 15N-labeled Riboflavin. Riboflavin is an easily absorbed micronutrient with a key role in maintaining health in humans and other animals.
|
-
- HY-I0626S
-
|
|
|
Cytosine- 13C2, 15N2 is the 13C-labeled and 15N-labeled Cytosine. Cytosine is one of the four main bases found in DNA and RNA. Cytosine modifications exhibit circadian oscillations that are involved in epigenetic diversity and aging[1][2].
|
-
- HY-N0667S2
-
|
|
|
L-Asparagine- 15N2 (monohydrate) is the 15N-labeled L-Asparagine. L-Asparagine ((-)-Asparagine) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue.
|
-
- HY-W010098S1
-
|
|
|
Terephthalic acid- 13C2 is the 13C-labeled Terephthalic acid. Terephthalic acid is one isomer of the three phthalic, a precursor to the polyester PET, used to make clothing and plastic bottles.
|
-
- HY-N0229S
-
|
|
|
L-Alanine-2- 13C, 15Nis the 13C-labeled and 15N-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.
|
-
- HY-B0315S
-
|
|
|
Vitamin B12- 13C7 is the 13C-labeled Vitamin B12. Vitamin B12 is a vitamin. Vitamin B12 plays a key role in the normal functioning of the brain and nervous system, and for the formation of blood[1][2].
|
-
- HY-B0430S
-
|
|
|
Pantothenic acid- 13C3, 15N (hemicalcium) is the 13C-labeled and 15N-labeled D-Pantothenic acid. D-Pantothenic acid is an essential trace nutrient that functions as the obligate precursor of coenzyme A (CoA). D-Pantothenic acid plays key roles in myriad biological processes, including many that regulate carbohydrate, lipid, protein, and nucleic acid metabolism[1].
|
-
- HY-B0574S2
-
|
|
|
Mefenamic acid- 13C6 is the 13C-labeled Mefenamic acid. Mefenamic acid is a non-steroidal anti-inflammatory agent, acting as a competitive inhibitor of hCOX-1 and hCOX-2, with IC50s of 40 nM and 3 μM for hCOX-1 and hCOX-2, respectively.
|
-
- HY-N0464S
-
|
|
|
Quinic acid- 13C3 is the 13C-labeled D-(-)-Quinic acid. D-(-)-Quinic acid is a cyclohexanecarboxylic acid and is implicated in the perceived acidity of coffee.
|
-
- HY-50723S
-
|
|
|
3-Methylxanthine- 13C4, 15N3 is the 13C-labeled and 15N-labeled 3-Methylxanthine. 3-Methylxanthine, a xanthine derivative, is a cyclic guanosine monophosphate (GMP) inhibitor, with an IC50 of 920 μM on guinea-pig isolated trachealis muscle.
|
-
- HY-Y0589S
-
|
|
|
m-Cyanobenzoic acid- 13C6 is the 13C labeled m-Cyanobenzoic acid[1].
|
-
- HY-Y0781S
-
|
|
|
Pyruvic acid- 13C (sodium) is the 13C-labeled Pyruvic acid. Pyruvic acid is an intermediate metabolite in the metabolism of carbohydrates, proteins, and fats.
|
-
- HY-141932S
-
|
|
|
4,4′-Methylenedianiline- 15N2, 13C is the 13C and 15N labeled 4,4′-Methylenedianiline[1].
|
-
- HY-W013396S
-
|
|
|
4-Iodobenzoic Acid- 13C6 is the 13C labeled 4-Iodobenzoic Acid[1].
|
-
- HY-N0666S1
-
|
|
|
L-Aspartic acid- 13C4, 15N is the 13C-labeled and 15N-labeled L-Aspartic acid. L-Aspartic acid is is an amino acid, shown to be a suitable proagent for colon-specific agent deliverly.
|
-
- HY-141941S
-
|
|
|
Triazole Lactic Acid- 13C2, 15N3 is the 13C and 15N labeled Triazole Lactic Acid[1].
|
-
- HY-I0210S
-
|
|
|
4-Iodoaniline- 13C6 is the 13C labeled 4-Iodoaniline[1].
|
-
- HY-N0683S1
-
|
|
|
α-Vitamin E- 13C3 is the 13C-labeled α-Vitamin E. α-Vitamin E ((+)-α-Tocopherol), a naturally occurring vitamin E form, is a potent antioxidant[1][2].
|
-
- HY-W009204S2
-
|
|
|
Fmoc-Ala-OH-1- 13C is the 13C labeled Fmoc-Ala-OH[1].
|
-
- HY-17461S
-
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|
|
Cortisone- 13C3 is the 13C-labeled Cortisone. Cortisone (17-Hydroxy-11-dehydrocorticosterone), an oxidized metabolite of Cortisol (a Glucocorticoid). Cortisone acts as an immunosuppressant and anti-inflammatory agent. Cortisone can partially intervene in binding of Glucocorticoid to Glucocorticoid-receptor at high concentrations[1][3][4].
|
-
- HY-W017072S
-
|
|
|
1-Dodecene-1,2- 13C2 is the 13C labeled 1-Dodecene[1].
|
-
- HY-131501S1
-
|
|
|
Menaquinone-9- 13C6 is the 13C labeled Menaquinone-9[1].
|
-
- HY-N0322S3
-
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|
|
Cholesterol- 13C5 is the 13C-labeled Cholesterol. Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins . Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist .
|
-
- HY-41121S
-
|
|
|
Boc-Ala-OH-1- 13C is the 13C labeled Boc-Ala-OH[1].
|
-
- HY-W015824S
-
|
|
|
DL-Aspartic acid- 13C is the 13C labeled DL-Aspartic acid[1].
|
-
- HY-15398S1
-
|
|
|
Vitamin D3- 13C3 is the 13C-labeled Vitamin D3. Vitamin D3 (Cholecalciferol; Colecalciferol) is a naturally occuring form of vitamin D. Vitamin D3 induces cell differentiation and prevents proliferation of cancer cells.
|
-
- HY-Y0219S
-
|
|
|
NSC 83128- 13C2, 15N3 is the 13C and 15N labeled NSC 83128[1].
|
-
- HY-Y0337S1
-
|
|
|
L-Cysteine- 15N is the 15N-labeled L-Cysteine. L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans[1].
|
-
- HY-W017443S1
-
|
|
|
L-Asparagine-amide- 15N (monohydrate) is the 15N-labeled L-Asparagine (monohydrate). L-Asparagine monohydrate ((-)-Asparagine monohydrate) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue.
|
-
- HY-10002S
-
|
|
|
Calcitriol- 13C3 is the 13C-labeled Calcitriol. Calcitriol is the most active metabolite of vitamin D and also a vitamin D receptor (VDR) agonist.
|
-
- HY-15407AS
-
|
|
|
Sacubitril- 13C4 (hemicalcium salt) is a 13C-labeled and deuterium labeled Sacubitril hemicalcium salt. Sacubitril (AHU-377) hemicalcium salt is a potent NEP inhibitor with an IC50 of 5 nM. Sacubitril hemicalcium salt is a component of the heart failure medicine LCZ696[1].
|
-
- HY-76929S
-
|
|
|
tert-Butyl 4-aminobenzoate- 13C6 is the 13C labeled tert-Butyl 4-aminobenzoate[1].
|
-
- HY-N0326S
-
|
|
|
L-Methionine- 15N is the 15N-labeled L-Methionine. L-Methionine is the L-isomer of Methionine, an essential amino acid for human development. Methionine acts as a hepatoprotectant.
|
-
- HY-N0437S1
-
|
|
|
Progesterone- 13C5 is the 13C-labeled Progesterone. Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy.
|
-
- HY-Y0271S
-
|
|
|
Urea- 15N2 is the 15N-labeled Urea. Urea is a powerful protein denaturant via both direct and indirect mechanisms[1]. A potent emollient and keratolytic agent[2]. Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function[3]. Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry.
|
-
- HY-B2039S
-
|
|
|
Bentazone- 13C10, 15N is the 13C-labeled and 15N-labeled Bentazone. Bentazone is a post-emergence herbicide used for selective control of broadleaf weeds and sedges in beans, rice, corn, peanuts, mint and others. It acts by interfering with photosynthesis[1].
|
-
- HY-18341S1
-
|
|
|
Thyroxine hydrochloride- 13C6 is the 13C-labeled L-Thyroxine. L-Thyroxine (Levothyroxine; T4) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4)[1].
|
-
- HY-16637S2
-
|
|
|
(Rac)-Folic acid- 13C5, 15N is the 13C-labeled and 15N-labeled Folic acid. Folic acid (Vitamin M; Vitamin B9) is a B vitamin; is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis.
|
-
- HY-Y1027S
-
|
|
|
2-Chlorobenzoic Acid- 13C7 is the 13C labeled 2-Chlorobenzoic Acid[1].
|
-
- HY-B1732S1
-
|
|
|
DL-3-Phenylalanine- 13C is the 13C labeled DL-3-Phenylalanine[1].
|
-
- HY-N0667S3
-
|
|
|
L-Asparagine- 13C4 (monohydrate) is the 13C-labeled L-Asparagine. L-Asparagine ((-)-Asparagine) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue.
|
-
- HY-W012722BS1
-
|
|
|
4-Methyl-2-oxopentanoic acid- 13C (sodium) is the 13C labeled 4-Methyl-2-oxopentanoic acid sodium[1].
|
-
- HY-Y0313S1
-
|
|
|
p-Hydroxybenzaldehyde- 13C is the 13C-labeled p-Hydroxybenzaldehyde. p-Hydroxybenzaldehyde is a one of the major components in Dendrocalamus asper bamboo shoots, with antagonistic effect on GABAA receptor of the α1β2γ2S subtype at high concentrations.
|
-
- HY-N0898S
-
|
|
|
Catechin- 13C3 is the 13C-labeled Catechin. Catechin ((+)-Catechin) inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM.
|
-
- HY-B0451AS1
-
|
|
|
Dopamine- 13C6 (hydrochloride) is the 13C labeled Dopamine hydrochloride (ASL279)[1].
|
-
- HY-W015883AS
-
|
|
|
Fumaric acid2,3- 13C2 (disodium) is the deuterium labeled Fumaric acid disodium[1].
|
-
- HY-B0456S2
-
|
|
|
Riboflavin- 13C5 is the 13C-labeled Riboflavin. Riboflavin is an easily absorbed micronutrient with a key role in maintaining health in humans and other animals.
|
-
- HY-50896S1
-
|
|
|
Erlotinib- 13C6 is a 13C-labeled Erlotinib. Erlotinib is a directly acting EGFR tyrosine kinase inhibitor, with an IC50 of 2 nM for human EGFR[1].
|
-
- HY-I0960S
-
|
|
|
Uracil- 13C2, 15N2 is the 13C-labeled and 15N-labeled Uracil. Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA.
|
-
- HY-N0771S
-
|
|
|
L-Isoleucine- 13C6 is the 13C-labeled L-Isoleucine. L-isoleucine is a nonpolar hydrophobic amino acid[1]. L-Isoleucine is an essential amino acid.
|
-
- HY-N0060S1
-
|
|
|
Ferulic acid- 13C3 is the 13C-labeled Ferulic acid. Ferulic acid is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC50s of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively.
|
-
- HY-141907S
-
|
|
|
17β-Estradiol- 13C3 is the 13C labeled 17β-Estradiol[1].
|
-
- HY-W015824S1
-
|
|
|
DL-Aspartic acid- 13C, 15N is the 13C, and 15N-labeled DL-Aspartic acid.
|
-
- HY-12857S
-
|
|
|
Brigatinib- 13C6 is the 13C-labeled Brigatinib. Brigatinib (AP-26113) is a highly potent and selective ALK inhibitor, with an IC50 of 0.6 nM[1].
|
-
- HY-10999S1
-
|
|
|
Trametinib- 13C6 is the 13C-labeled Trametinib. Trametinib (GSK1120212; JTP-74057) is an orally active MEK inhibitor that inhibits MEK1 and MEK2 with IC50s of about 2 nM. Trametinib activates autophagy and induces apoptosis[1][2].
|
-
- HY-40354S
-
|
|
|
Tofacitinib- 13C3 is the 13C-labeled Tofacitinib. Tofacitinib is an orally available JAK3/2/1 inhibitor with IC50s of 1, 20, and 112 nM, respectively.
|
-
- HY-135330
-
|
|
|
Lamivudine- 13C, 15N2 is a labelled impurity of Lamivudine (BCH-189). Lamivudine is a nucleoside reverse transcriptase inhibitors (NRTIs), and can inhibit HIV reverse transcriptase 1/2 and the reverse transcriptase of hepatitis B virus .
|
-
- HY-133706S
-
|
|
|
2-Nitrobenzaldehyde semicarbazone- 13C, 15N2 is used for analysis of semicarbazide in the LC-MS/MS method .
|
-
- HY-17598S
-
|
|
|
Rafoxanide 13C6 is a labeled Rafoxanide (HY-17598). Rafoxanide is a salicylanilide used as an antiparasitic agent[1].
|
-
- HY-15306S
-
1 Publications Verification
|
|
Eltrombopag- 13C4 (SB-497115- 13C4) is 13 sup>C-labeled Z-Eltrombopag. Z-Eltrombopag is an orally active thrombopoietin-receptor non-peptide agonist with platelet-stimulating activity for the study of chronic immune thrombocytopenia. Eltrombopag also has strong inhibitory effects on multidrug-resistant Staphylococcus aureus (Staphylococcus aureus) and can induce apoptosis (apoptosis) in liver cancer cells .
|
-
- HY-Y0479S
-
|
|
|
L-Lactic acid- 13C3 is a 13C-labeled L-Lactic acid (HY-Y0479). L-Lactic acid- 13C3 can be used for lactate metabolism research .
|
-
- HY-107372S
-
|
|
|
Uridine triphosphate- 13C9, 15N2 (sodium) is a labeled Uridine triphosphate sodium. Uridine triphosphate sodium can be used in nucleic acid synthesis.
|
-
- HY-N0229S2
-
|
|
|
L-Alanine- 15N is the 15N-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system[1].
|
-
- HY-N0455AS1
-
|
|
|
L-Arginine- 15N4 (hydrochloride) is the 15N-labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis[1].
|
-
- HY-N0666S3
-
|
|
|
L-Aspartic acid- 15N is the 15N-labeled L-Aspartic acid. L-Aspartic acid is is an amino acid, shown to be a suitable proagent for colon-specific agent deliverly[1].
|
-
- HY-Y0966S
-
|
|
|
Glycine- 15N is the 15N-labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors[1].
|
-
- HY-14608S2
-
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|
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L-Glutamic acid- 15N is the 15N-labeled L-Glutamic acid. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals[1].
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- HY-N0486S3
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L-Leucine- 15N is the 15N-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway[1][2].
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- HY-N0771S2
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L-Isoleucine-15N is the 15N-labeled L-Isoleucine. L-isoleucine is a nonpolar hydrophobic amino acid. L-Isoleucine is an essential amino acid .
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- HY-N0215S5
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L-Phenylalanine- 15N is the 15N-labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4].
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- HY-Y0252S2
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L-Proline- 15N is the 15N-labeled L-Proline. L-Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins[1].
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- HY-N0658S
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L-Threonine- 15N is the 15N-labeled L-Threonine. L-Threonine is a natural amino acid, can be produced by microbial fermentation, and is used in food, medicine, or feed[1][2].
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- HY-N0717S
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L-Valine- 15N is the 15N-labeled L-Valine. L-Valine is one of 20 proteinogenic amino acids. L-Valine is an essential amino acid[1][2].
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- HY-N0650S
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L-Serine- 13C3 is the 13C-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.
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- HY-N7091S1
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Atrazine- 13C3, 15N3 is the 13C-labeled and 15N-labeled Atrazine. Atrazine is principally used for control of certain annual broadleaf and grass weeds. Atrazine inhibits photophosphorylation but typically does not result in lethality or permanent cell damage in the short term[1].
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- HY-113008AS
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cis-Urocanic acid- 13C3 is the 13C-labeled cis-Urocanic acid. cis-Urocanic acid is a 5-HT2A receptor agonist. cis-Urocanic acid binds to 5-HT receptor with relatively high affinity (Kd=4.6 nM). cis-Urocanic acid is an immune modulator that induces immunosuppression by binding to the 5-HT2A receptor[1].
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- HY-100760S
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Toxoflavin- 13C4 is the 13C-labeled Toxoflavin. Toxoflavin (Xanthothricin) is an antagonist of transcription factor 4 (TCF4)/β-catenin complex, also acts as an inhibitor of KDM4A, with antitumor activity[1][2]. Antibiotic properties.
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- HY-113357S
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m-Coumaric acid- 13C3 is the 13C-labeled m-Coumaric acid. m-Coumaric acid is a polyphenol metabolite from caffeic acid, formed by the gut microflora and the amount in human biofluids is diet-dependant.
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- HY-113046S
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5-Methyltetrahydrofolic acid- 13C5 is the 13C-labeled 5-Methyltetrahydrofolic acid. 5-Methyltetrahydrofolic acid (5-Methyl THF) is a biologically active form of folic acid. 5-Methyltetrahydrofolic acid is a methylated derivate of tetrahydrofolate. 5-Methyltetrahydrofolic acid is the predominant natural dietary folate and the principal form of folate in plasma and cerebrospinal fluid[1].
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- HY-112499S1
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Menaquinone-7- 13C6 is the 13C-labeled Menaquinone-7. Menaquinone-7 (Vitamin K2-7), belongs to a class of K2-vitamin homologs, is originally discovered as the anti-hemorrhagic factors[1]. Menaquinone-7 (Vitamin K2-7) is identified as the most bioactive cofactor for the carboxylation reaction of Gla-proteins [2]. Supplementation with Menaquinone-7 (Vitamin K2-7) is a pharmacological option for activating matrix Gla protein and intervening in the progression of calcific aortic valve stenosis (CAVS)[3].
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- HY-136380S
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Clodinafop-propargyl- 13C6 is the 13C-labeled Clodinafop-propargyl. Clodinafop-propargyl, a main member of aryloxyphenoxy-propionate herbicides, is used for postemergence control of annual grasses in cereals, including Avena, Lolium, Setaria, Phalaris and Alopecurus spp[1]. Clodinafop-propargyl-13C6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-N0680S
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Thiamine monochloride- 13C4 (hydrochloride) is the deuterium labeled Thiamine hydrochloride. Thiamine hydrochloride (Thiamine chloride hydrochloride) is an essential micronutrient needed as a cofactor for many central metabolic enzymes.
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- HY-141902S
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FMOC-L-Glutamic Acid- 13C5, 15N-5-t-butyl ester is the 13C and 15N labeled FMOC-L-Glutamic Acid-5-t-butyl ester[1].
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- HY-113296S
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Indoxyl Sulfate Potassium Salt- 13C6 is the 13C labeled Indoxyl Sulfate Potassium Salt[1].
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-
- HY-133689AS
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3-Nitrophenylhydrazine- 13C6 (hydrochloride) is the 13C labeled 3-Nitrophenylhydrazine hydrochloride[1].
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- HY-121267S
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Dicamba- 13C6 is the 13C labeled Dicamba[1].
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- HY-113062S
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20a-Dihydroprogesterone- 13C5 is the 13C labeled 20a-Dihydroprogesterone[1].
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- HY-139921S1
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Nordiazepam- 13C6 is the 13C labeled Nordiazepam[1].
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- HY-Y0721S
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3-Bromofluorobenzene- 13C6 is the 13C labeled 3-Bromofluorobenzene[1].
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- HY-N0830BS
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Palmitic acid- 13C (sodium) is the 13C-labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. Palmitic acid can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells[1][2].
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- HY-N0830BS1
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3 Publications Verification
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Palmitic acid- 13C16 (sodium) is the 13C-labeled Palmitic acid sodium. Palmitic acid sodium is a long-chain saturated fatty acid commonly found in both animals and plants. Palmitic acid sodium can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells[1][2].
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- HY-N0830S
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Palmitic acid-1,2,3,4- 13C4 is the 13C-labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. Palmitic acid can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells[1][2].
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-
- HY-N0830S10
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Palmitic acid- 13C2 is the 13C-labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. Palmitic acid can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells[1][2].
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- HY-N0830S3
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Palmitic acid-1- 13C is the 13C-labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. Palmitic acid can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells[1][2].
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- HY-N0830S9
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Palmitic acid- 13C is the 13C-labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. Palmitic acid can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells[1][2].
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- HY-138622S
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24:0 Lyso PC- 13C6 is the 13C labeled 24:0 Lyso PC. 24:0 Lyso PC is a lysophospholipid (LyP). 24:0 Lyso PC could be used for mRNA drug delivery[1].
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- HY-N1446S
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Oleic acid- 13C is the 13C labeled Oleic acid (HY-N1446). Oleic acid (9-cis-Octadecenoic acid) is an abundant monounsaturated fatty acid . Oleic acid is a Na+/K+ ATPase activator .
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- HY-Y0366S
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Lauric acid- 13C is the 13C labeled Lauric acid. Lauric acid is a middle chain-free fatty acid with strong bactericidal properties. The EC50s for P. acnes, S.aureus, S. epidermidis, are 2, 6, 4 μg/mL, respectively.
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-
- HY-W013061S1
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Propane-1,2,3-triyl tripalmitate- 13C3 is the 13C labeled Propane-1,2,3-triyl tripalmitate. Propane-1,2,3-triyl tripalmitate is an endogenous metabolite.
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- HY-N2041S2
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Myristic acid- 13C the 13C is labeled Myristic acid. Myristic acid is a saturated 14-carbon fatty acid occurring in most animal and vegetable fats, particularly butterfat and coconut, palm, and nutmeg oils.
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- HY-W012980S1
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Isovaleric acid- 13C is the 13C labeled Isovaleric acid. Isovaleric acid is a natural fatty acid and known to effect on neonatal death and possible Jamaican vomiting sickness in human.
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- HY-W011873S2
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Palmitoleic acid- 13C16 is the 13C labeled Palmitoleic acid. Palmitoleic acid, a composition of fatty acid, is implicated in the prevention of death from cerebrovascular disorders in SHRSP rats.
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- HY-N1446S4
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Oleic acid- 13C-1 is the 13C labeled Oleic acid (HY-N1446). Oleic acid (9-cis-Octadecenoic acid) is an abundant monounsaturated fatty acid . Oleic acid is a Na+/K+ ATPase activator .
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- HY-41417S4
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Octanoic acid- 13C4 is the 13C labeled Octanoic acid. Octanoic acid (Caprylic acid) is an oily liquid with a slightly unpleasant rancid taste and used commercially in the production of esters used in perfumery and also in the manufacture of dyes.
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- HY-41417S3
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Octanoic acid- 13C is the 13C labeled Octanoic acid. Octanoic acid (Caprylic acid) is an oily liquid with a slightly unpleasant rancid taste and used commercially in the production of esters used in perfumery and also in the manufacture of dyes.
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-
- HY-W013061S4
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Propane-1,2,3-triyl tripalmitate- 13C3-1 is the 13C labeled Propane-1,2,3-triyl tripalmitate. Propane-1,2,3-triyl tripalmitate is an endogenous metabolite.
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- HY-N2041S4
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Myristic acid- 13C3 is the 13C labeled Myristic acid. Myristic acid is a saturated 14-carbon fatty acid occurring in most animal and vegetable fats, particularly butterfat and coconut, palm, and nutmeg oils.
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- HY-W013812S
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Ethyl linoleate- 13C18 is the 13C labeled Ethyl linoleate. Ethyl linoleate inhibit the development of atherosclerotic lesions and the expression of inflammatory mediators[1].
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- HY-N1446S2
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Oleic acid- 13C18 is the 13C labeled Oleic acid (HY-N1446). Oleic acid (9-cis-Octadecenoic acid) is an abundant monounsaturated fatty acid . Oleic acid is a Na+/K+ ATPase activator .
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- HY-B2219S
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Stearic acid-1- 13C is the 13C labeled Stearic acid. Stearic acid is a long chain dietary saturated fatty acid which exists in many animal and vegetable fats and oils.
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- HY-N0729S2
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Linoleic acid- 13C18 is the 13C labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism [1][2].
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- HY-N0322S5
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Cholesterol- 13C2 is the 13C labeled Cholesterol. Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins . Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist .
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- HY-N0728S3
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α-Linolenic acid- 13C18 is the 13C labeled α-Linolenic acid. α-Linolenic acid, isolated from seed oils, is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer[1].
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- HY-N1482S
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Methyl palmitate- 13C16 is the 13C labeled Methyl palmitate. Methyl palmitate, an acaricidal compound occurring in green walnut husks, inhibits phagocytic activity and immune response. Methyl palmitate also posseses anti-inflammatory and antifibrotic effects[1][2][3].
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- HY-N0729S3
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Linoleic acid- 13C1 is the 13C labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism [1][2].
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- HY-Y0520S
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Itaconic acid- 13C5 is the 13C labeled Itaconic acid. Itaconic acid, a precursor of polymers, chemicals, and fuels, can be synthesized by many fungi. Itaconic acid also is a macrophage-specific metabolite. Itaconic acid mediates crosstalk between macrophage metabolism and peritoneal tumors[1][2].
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- HY-N7092S1
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D-Fructose- 13C is the 13C labeled D-Fructose. D-Fructose (D(-)-Fructose) is a naturally occurring monosaccharide found in many plants.
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- HY-B0389S10
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D-Glucose- 13C is the 13C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].
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- HY-B0389S11
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D-Glucose- 13C-1 is the 13C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].
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- HY-B0389S12
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D-Glucose- 13C-2 is the 13C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].
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- HY-N7092S2
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D-Fructose- 13C-1 is the 13C labeled D-Fructose. D-Fructose (D(-)-Fructose) is a naturally occurring monosaccharide found in many plants.
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- HY-N7092S
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D-Fructose- 13C6 is the 13C labeled D-Fructose. D-Fructose (D(-)-Fructose) is a naturally occurring monosaccharide found in many plants.
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- HY-B0389S14
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D-Glucose- 13C2 is the 13C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].
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- HY-B0389S16
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D-Glucose- 13C-4 is the 13C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].
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- HY-B0389S18
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D-Glucose- 13C3-1 is the 13C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].
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- HY-B0389S17
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D-Glucose- 13C-5 is the 13C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].
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- HY-B0389S15
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D-Glucose- 13C2-4 is the 13C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].
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- HY-N7092S3
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D-Fructose- 13C2 is the 13C labeled D-Fructose. D-Fructose (D(-)-Fructose) is a naturally occurring monosaccharide found in many plants.
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- HY-B0389S13
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D-Glucose- 13C-3 is the 13C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].
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- HY-B0389S9
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D-Glucose- 13C3-2 is the 13C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].
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- HY-101037S
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Sarcosine- 15N is the 15N-labeled Sarcosine. Sarcosine (N-Methylglycine), an endogenous amino acid, is a competitive glycine transporter type I (GlyT1) inhibitor and N-methyl-D-aspartate (NMDA) receptor co-agonist. Sarcosine increases the glycine concentration, resulting in an indirect potentiation of the NMDA receptor. Sarcosine is commonly used for the research of schizophrenia[1][2].
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- HY-140346AS
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L-Azidohomoalanine-1,2,3,4- 13C4 (hydrochloride) is the 13C- and 15N-labeled L-Azidohomoalanine hydrochloride. L-Azidohomoalanine hydrochloride is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. L-Azidohomoalanine-1,2,3,4-13C4 (hydrochloride) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-14608S3
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L-Glutamic acid- 13C5, 15N is the 13C- and 15N-labeled L-Glutamic acid. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals.
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- HY-14608S5
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L-Glutamic acid- 13C5 is the 13C-labeled L-Glutamic acid. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals.
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- HY-14608S6
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L-Glutamic acid-5- 13C is the 13C-labeled L-Glutamic acid. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals.
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- HY-N0067S3
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γ-Aminobutyric acid- 13C4 is the 13C-labeled γ-Aminobutyric acid. γ-Aminobutyric acid (4-Aminobutyric acid) is a major inhibitory neurotransmitter in the adult mammalian brain[1][2], binding to the ionotropic GABA receptors (GABAA receptors) and metabotropic receptors (GABAB receptors)[2].
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- HY-N0215S10
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L-Phenylalanine- 13C9 is the 13C-labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4].
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- HY-N0215S11
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L-Phenylalanine- 13C9, 15N is the 13C- and 15N-labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4].
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- HY-N0215S7
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L-Phenylalanine-3- 13C is the 13C-labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4].
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- HY-N0215S8
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L-Phenylalanine- 13C6 is the 13C-labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4].
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- HY-N0229S10
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L-Alanine- 13C3, 15N is the 13C- and 15N-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.
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- HY-N0229S11
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L-Alanine-1- 13C, 15N is the 13C- and 15N-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.
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- HY-N0229S6
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L-Alanine-3- 13C is the 13C-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.
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- HY-N0229S7
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L-Alanine-2- 13C is the 13C-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.
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-
- HY-N0229S8
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L-Alanine- 13C3 is the 13C-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.
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-
- HY-N0229S9
-
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L-Alanine- 13C2 is the 13C-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.
|
-
- HY-N0230S
-
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|
|
β-Alanine- 13C3, 15N is the 13C- and 15N-labeled β-Alanine. β-Alanine is a non-essential amino acid that is shown to be metabolized into carnosine, which functions as an intracellular buffer.
|
-
- HY-N0230S1
-
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|
|
β-Alanine- 15N is the 15N-labeled β-Alanine. β-Alanine is a non-essential amino acid that is shown to be metabolized into carnosine, which functions as an intracellular buffer.
|
-
- HY-N0326S3
-
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|
|
L-Methionine- 13C is the 13C-labeled L-Methionine. L-Methionine is the L-isomer of Methionine, an essential amino acid for human development. Methionine acts as a hepatoprotectant.
|
-
- HY-N0326S4
-
|
|
|
L-Methionine-1- 13C is the 13C-labeled L-Methionine. L-Methionine is the L-isomer of Methionine, an essential amino acid for human development. Methionine acts as a hepatoprotectant.
|
-
- HY-N0326S5
-
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|
|
L-Methionine- 13C5 is the 13C-labeled L-Methionine. L-Methionine is the L-isomer of Methionine, an essential amino acid for human development. Methionine acts as a hepatoprotectant.
|
-
- HY-N0326S6
-
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|
|
L-Methionine- 13C5, 15N is the 13C- and 15N-labeled L-Methionine. L-Methionine is the L-isomer of Methionine, an essential amino acid for human development. Methionine acts as a hepatoprotectant.
|
-
- HY-N0390S4
-
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|
L-Glutamine-5- 13C is the 13C-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells[1][2].
|
-
- HY-N0390S5
-
1 Publications Verification
|
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L-Glutamine-1- 13C is the 13C-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells[1][2].
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-
- HY-N0390S6
-
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|
|
L-Glutamine- 13C5, 15N2 is the 13C- and 15N-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells[1][2].
|
-
- HY-N0390S8
-
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|
|
L-Glutamine- 15N2 is the 15N-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells[1][2].
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-
- HY-N0390S9
-
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|
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L-Glutamine- 15N-1 is the 15N-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells[1][2].
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-
- HY-N0391S3
-
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|
L-Citrulline- 13C is the 13C-labeled L-Citrulline. L-Citrulline is an amino acid derived from ornithine in the catabolism of proline or glutamine and glutamate, or from l-arginine via arginine-citrulline pathway.
|
-
- HY-N0394S2
-
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(S)-L-Cystine- 15N2 is the 15N-labeled L-Cystine. L-Cystine is an amino acid and intracellular thiol, which plays a critical role in the regulation of cellular processes.
|
-
- HY-N0455AS3
-
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|
|
L-Arginine-1- 13C (hydrochloride) is the 13C-labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.
|
-
- HY-N0455AS5
-
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|
|
L-Arginine-1,2- 13C2 (hydrochloride) is the 13C-labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.
|
-
- HY-N0455AS6
-
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|
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L-Arginine- 13C6 (hydrochloride) is the 13C-labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.
|
-
- HY-N0455AS7
-
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|
|
L-Arginine- 13C (hydrochloride) is the 13C-labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.
|
-
- HY-N0455AS8
-
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|
|
L-Arginine- 13C6, 15N4 (hydrochloride) is the 13C- and 15N-labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.
|
-
- HY-N0469S1
-
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|
|
L-Lysine- 13C6 (dihydrochloride) is the 13C-labeled L-Lysine dihydrochloride. L-lysine dihydrochloride is an essential amino acid[1][2] with important roles in connective tissues and carnitine synthesis, energy production, growth in children, and maintenance of immune functions[2].
|
-
- HY-N0469S2
-
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|
|
L-Lysine- 15N-1 (dihydrochloride) is the 15N-labeled L-Lysine. L-lysine is an essential amino acid[1][2] with important roles in connective tissues and carnitine synthesis, energy production, growth in children, and maintenance of immune functions[2].
|
-
- HY-N0470S2
-
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|
|
L-Lysine- 13C (dihydrochloride) is the 13C-labeled L-Lysine dihydrochloride. L-lysine dihydrochloride is an essential amino acid for humans with various benefits including treating herpes, increasing calcium absorption, reducing diabetes-related illnesses and improving gut health.
|
-
- HY-N0473S12
-
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L-Tyrosine- 17O is the 17O-labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.
|
-
- HY-N0473S2
-
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|
|
L-Tyrosine- 13C6 is the 13C-labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.
|
-
- HY-N0473S3
-
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|
|
L-Tyrosine- 13C9 is the 13C-labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.
|
-
- HY-N0473S4
-
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|
|
L-Tyrosine- 13C is the 13C-labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.
|
-
- HY-N0473S5
-
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|
|
L-Tyrosine-4- 13C is the 13C-labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.
|
-
- HY-N0473S6
-
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|
|
L-Tyrosine-3,5- 13C2 is the 13C-labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.
|
-
- HY-N0473S7
-
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|
|
L-Tyrosine-1- 13C is the 13C-labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.
|
-
- HY-N0486S10
-
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|
|
L-Leucine- 18O2 is the 18O-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway[1].
|
-
- HY-N0486S5
-
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|
|
L-Leucine-2- 13C is the 13C-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway[1].
|
-
- HY-N0486S6
-
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|
|
L-Leucine-2- 13C, 15N is the 13C- and 15N-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway[1].
|
-
- HY-N0486S7
-
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|
|
L-Leucine-1- 13C, 15N is the 13C- and 15N-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway[1].
|
-
- HY-N0486S8
-
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|
L-Leucine- 13C6, 15N is the 13C- and 15N-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway[1].
|
-
- HY-N0623S1
-
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|
L-Tryptophan- 13C is the 13C-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1].
|
-
- HY-N0623S2
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|
L-Tryptophan- 13C11 is the 13C-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1].
|
-
- HY-N0623S3
-
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|
|
L-Tryptophan-1- 13C is the 13C-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1].
|
-
- HY-N0623S4
-
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|
|
L-Tryptophan- 13C11, 15N2 is the 13C- and 15N-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1].
|
-
- HY-N0623S7
-
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|
|
L-Tryptophan- 15N is the 15N-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1].
|
-
- HY-N0623S8
-
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|
|
L-Tryptophan- 15N2 is the 15N-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1].
|
-
- HY-N0650S1
-
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|
|
L-Serine- 13C is the 13C-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.
|
-
- HY-N0650S10
-
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|
|
L-Serine- 15N is the 15N-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.
|
-
- HY-N0650S2
-
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|
|
L-Serine-1- 13C is the 13C-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.
|
-
- HY-N0650S4
-
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|
|
L-Serine-2- 13C is the 13C-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.
|
-
- HY-N0650S5
-
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|
|
L-Serine- 13C3, 15N is the 13C- and 15N-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.
|
-
- HY-N0650S6
-
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|
|
L-Serine1- 13C, 15N is the 13C- and 15N-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.
|
-
- HY-N0658S3
-
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|
|
L-Threonine- 13C4, 15N is the 13C- and 15N-labeled L-Threonine. L-Threonine is a natural amino acid, can be produced by microbial fermentation, and is used in food, medicine, or feed[1].
|
-
- HY-N0666S4
-
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|
|
L-Aspartic acid- 13C4 is the 13C-labeled L-Aspartic acid. L-Aspartic acid is is an amino acid, shown to be a suitable proagent for colon-specific agent deliverly.
|
-
- HY-N0666S6
-
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|
|
L-Aspartic acid-1,4- 13C2 is the 13C-labeled L-Aspartic acid. L-Aspartic acid is is an amino acid, shown to be a suitable proagent for colon-specific agent deliverly.
|
-
- HY-N0666S7
-
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|
|
L-Aspartic acid-1,4- 13C2, 15N is the 13C- and 15N-labeled L-Aspartic acid. L-Aspartic acid is is an amino acid, shown to be a suitable proagent for colon-specific agent deliverly.
|
-
- HY-N0717S1
-
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|
|
L-Valine- 13C5, 15N is the 13C- and 15N-labeled L-Valine. L-Valine is one of 20 proteinogenic amino acids. L-Valine is an essential amino acid[1].
|
-
- HY-N0717S4
-
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|
|
L-Valine-1- 13C is the 13C-labeled L-Valine. L-Valine is one of 20 proteinogenic amino acids. L-Valine is an essential amino acid[1].
|
-
- HY-N0717S5
-
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|
|
L-Valine-2- 13C is the 13C-labeled L-Valine. L-Valine is one of 20 proteinogenic amino acids. L-Valine is an essential amino acid[1].
|
-
- HY-N0717S6
-
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|
|
L-Valine- 13C5 is the 13C-labeled L-Valine. L-Valine is one of 20 proteinogenic amino acids. L-Valine is an essential amino acid[1].
|
-
- HY-N0717S7
-
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|
|
L-Valine-1- 13C, 15N is the 13C- and 15N-labeled L-Valine. L-Valine is one of 20 proteinogenic amino acids. L-Valine is an essential amino acid[1].
|
-
- HY-N0771S4
-
1 Publications Verification
|
|
L-Isoleucine-1- 13C is the 13C-labeled L-Isoleucine. L-isoleucine is a nonpolar hydrophobic amino acid[1]. L-Isoleucine is an essential amino acid.
|
-
- HY-N2362S
-
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|
|
DL-Alanine- 13C-1 is the 13C-labeled DL-Alanine. DL-alanine, an amino acid, is the racemic compound of L- and D-alanine. DL-alanine is employed both as a reducing and a capping agent, used with silver nitrate aqueous solutions for the production of nanoparticles. DL-alanine can be used for the research of transition metals chelation, such as Cu(II), Zn(II), Cd(11). DL-alanine, a sweetener, is classed together with glycine, and sodium saccharin. DL-alanine plays a key role in the glucose-alanine cycle between tissues and liver[1][2][3][4][5][6].
|
-
- HY-N2362S1
-
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|
|
DL-Alanine- 13C-3 is the 13C-labeled DL-Alanine. DL-alanine, an amino acid, is the racemic compound of L- and D-alanine. DL-alanine is employed both as a reducing and a capping agent, used with silver nitrate aqueous solutions for the production of nanoparticles. DL-alanine can be used for the research of transition metals chelation, such as Cu(II), Zn(II), Cd(11). DL-alanine, a sweetener, is classed together with glycine, and sodium saccharin. DL-alanine plays a key role in the glucose-alanine cycle between tissues and liver[1][2][3][4][5][6].
|
-
- HY-W008452S
-
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|
|
H-Tyr(3-I)-OH- 13C6 is the 13C-labeled H-Tyr(3-I)-OH. H-Tyr(3-I)-OH is a potent and effective tyrosine hydroxylase inhibitor. H-Tyr(3-I)-OH is an intermediate in the production of thyroid hormones and has a role as a human or mouse metabolite[1][2].
|
-
- HY-W012340S
-
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|
|
L-Homoarginine- 13C7, 15N4 (hydrochloride) is the 13C- and 15N-labeled H-HomoArg-OH.HCl. H-HomoArg-OH.HCl is an endogenous metabolite.
|
-
- HY-W014423S
-
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|
|
L-Histidine- 13C (hydrochloride hydrate) is the 13C-labeled L-Histidine hydrochloride hydrate. L-Histidine hydrochloride hydrate (H-His-OH.HCl.H2O) is an endogenous metabolite.
|
-
- HY-W014423S2
-
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|
|
L-Histidine- 13C6 (hydrochloride hydrate) is the 13C-labeled L-Histidine hydrochloride hydrate. L-Histidine hydrochloride hydrate (H-His-OH.HCl.H2O) is an endogenous metabolite.
|
-
- HY-W014423S3
-
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|
|
L-Histidine- 13C6, 15N3 (hydrochloride hydrate) is the 13C- and 15N-labeled L-Histidine hydrochloride hydrate. L-Histidine hydrochloride hydrate (H-His-OH.HCl.H2O) is an endogenous metabolite.
|
-
- HY-W014423S5
-
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|
|
L-Histidine- 15N3 (hydrochloride hydrate) is the 15N-labeled L-Histidine hydrochloride hydrate. L-Histidine hydrochloride hydrate (H-His-OH.HCl.H2O) is an endogenous metabolite.
|
-
- HY-W014423S6
-
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|
|
L-Histidine- 15N (hydrochloride hydrate) is the 15N-labeled L-Histidine hydrochloride hydrate. L-Histidine hydrochloride hydrate (H-His-OH.HCl.H2O) is an endogenous metabolite.
|
-
- HY-W016562S3
-
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|
Hippuric acid- 15N is the 15N-labeled Hippuric acid. Hippuric Acid (2-Benzamidoacetic acid), an acyl glycine produced by the conjugation of benzoic acid and glycine, is a normal component in urine as a metabolite of aromatic compounds from food.
|
-
- HY-W017018S1
-
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L-Ornithine-1,2- 13C2 (hydrochloride) is the 13C-labeled L-Ornithine hydrochloride. L-Ornithine hydrochloride is a free amino acid that plays a central role in the urea cycle and is also important for the disposal of excess nitrogen.
|
-
- HY-W017018S2
-
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L-Ornithine-1,2,3,4,5- 13C5 (hydrochloride) is the 13C-labeled L-Ornithine hydrochloride. L-Ornithine hydrochloride is a free amino acid that plays a central role in the urea cycle and is also important for the disposal of excess nitrogen.
|
-
- HY-W017018S5
-
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|
|
L-Ornithine- 15N2 (hydrochloride) is the 15N-labeled L-Ornithine hydrochloride. L-Ornithine hydrochloride is a free amino acid that plays a central role in the urea cycle and is also important for the disposal of excess nitrogen.
|
-
- HY-Y0123S
-
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DL-Tyrosine- 13C9, 15N is the 13C- and 15N-labeled DL-Tyrosine. DL-Tyrosine is an aromatic nonessential amino acid synthesized from the essential amino acid phenylalanine. DL-Tyrosine is a precursor for several important neurotransmitters (epinephrine, norepinephrine, dopamine)[1].
|
-
- HY-Y0252S3
-
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|
L-Proline- 13C is the 13C-labeled L-Proline. L-Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins.
|
-
- HY-Y0252S4
-
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L-Proline- 13C5,1- 15N is the 13C- and 15N-labeled L-Proline. L-Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins.
|
-
- HY-Y0337S
-
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|
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L-Cysteine- 13C3, 15N is the 13C- and 15N-labeled L-Cysteine. L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans[1].
|
-
- HY-Y0337S2
-
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|
|
L-Cysteine-3- 13C is the 13C-labeled L-Cysteine. L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans[1].
|
-
- HY-Y0337S3
-
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|
|
L-Cysteine-1- 13C is the 13C-labeled L-Cysteine. L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans[1].
|
-
- HY-Y0337S4
-
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|
|
L-Cysteine- 13C3 is the 13C-labeled L-Cysteine. L-Cysteine is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans[1].
|
-
- HY-Y0966S2
-
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|
|
Glycine-2- 13C is the 13C-labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors.
|
-
- HY-Y0966S3
-
|
|
|
Glycine- 13C2 is the 13C-labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors.
|
-
- HY-Y0966S4
-
|
|
|
Glycine-1- 13C is the 13C-labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors.
|
-
- HY-Y0966S5
-
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|
|
Glycine-1- 13C, 15N is the 13C- and 15N-labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors.
|
-
- HY-Y0966S6
-
|
|
|
Glycine- 13C2, 15N is the 13C- and 15N-labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors.
|
-
- HY-Y0966S7
-
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|
|
Glycine-2- 13C, 15N is the 13C- and 15N-labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors.
|
-
- HY-118877
-
1 Publications Verification
|
|
Urea- 13C is the 13C labelled urea. The Urea- 13C breath test ( 13C-UBT) is one of the best methods for the diagnosis of Helicobacter pylori infection[1].
|
-
- HY-113251S1
-
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|
|
2-Hydroxyestrone- 13C6 is the 13C-labeled 2-Hydroxyestrone. 2-Hydroxyestrone (Catecholestrone) is a specific receptor-mediated antiestrogenic agent. 2-Hydroxyestrone is anticarcinogenic[1][2].
|
-
- HY-113252S1
-
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|
|
2-Methoxyestrone- 13C6 is the 13C-labeled 2-Methoxyestrone. 2-Methoxyestrone is a methoxylated catechol estrogen and metabolite of estrone, with a pKa of 10.81.
|
-
- HY-12033S1
-
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|
|
2-Methoxyestradiol- 13C6 is the 13C-labeled 2-Methoxyestradiol. 2-Methoxyestradiol (2-ME2), an orally active endogenous metabolite of 17β-estradiol (E2), is an apoptosis inducer and an angiogenesis inhibitor with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules. 2-Methoxyestradio, also a potent superoxide dismutase (SOD) inhibitor and a ROS-generating agent, induces autophagy in the transformed cell line HEK293 and the cancer cell lines U87 and HeLa[1][2][3][4][5][6].
|
-
- HY-124489S
-
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|
|
2-Hydroxyestradiol- 13C6 is the 13C-labeled 2-Hydroxyestradiol. 2-Hydroxyestradiol, a metabolite of 17β-estradiol with minimal estrogenic activity, possesses antioxidant effects and reacts with DNA to form stable adducts and exerts genotoxicity[1][3].
|
-
- HY-76847S2
-
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|
|
Chenodeoxycholic acid- 13C is the 13C-labeled Chenodeoxycholic Acid. Chenodeoxycholic Acid is a hydrophobic primary bile acid that activates nuclear receptors (FXR) involved in cholesterol metabolism.
|
-
- HY-B0141S4
-
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Estradiol- 13C6 is the 13C-labeled Estradiol. Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway[1][2][3].
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- HY-B0141S5
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Estradiol- 13C2 is the 13C-labeled Estradiol. Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway[1][2][3].
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-
- HY-B0143S3
-
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Niacin- 13C6 is the 13C-labeled Niacin. Niacin (Nicotinic acid) is a vitamin and is part of the vitamin B group.
|
-
- HY-B0150S2
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Nicotinamide- 13C6 is the 13C-labeled Nicotinamide. Nicotinamide is a form of vitamin B3 that plays essential roles in cell physiology through facilitating NAD+ redox homeostasis and providing NAD+ as a substrate to a class of enzymes that catalyze non-redox reactions. Nicotinamide is an inhibitor of SIRT1.
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-
- HY-B0166S
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L-Ascorbic acid- 13C6 is the 13C-labeled L-Ascorbic acid. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor[1][2][3]. L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells[4].
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-
- HY-B0166S1
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L-Ascorbic acid- 13C is the 13C-labeled L-Ascorbic acid. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor[1][2][3]. L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells[4].
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-
- HY-B0216S2
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Ethynyl Estradiol- 13C2 is the 13C-labeled Ethynyl Estradiol. Ethynyl Estradiol-13C2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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-
- HY-B0234S3
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Estrone- 13C2 is the 13C-labeled Estrone. Estrone (E1) is a natural estrogenic hormone. Estrone is the main representative of the endogenous estrogens and is produced by several tissues, especially adipose tissue. Estrone is the result of the process of aromatization of androstenedione that occurs in fat cells[1][2].
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- HY-B0351S1
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Taurine- 13C2 is the 13C-labeled Taurine. Taurine, a sulphur-containing amino acid and an organic osmolyte involved in cell volume regulation, provides a substrate for the formation of bile salts, and plays a role in the modulation of intracellular free calcium concentration. Taurine has the ability to activate autophagy in adipocytes[1][2][3].
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-
- HY-B0351S2
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Taurine- 13C2, 15N is the 13C- and 15N- labeled Taurine. Taurine, a sulphur-containing amino acid and an organic osmolyte involved in cell volume regulation, provides a substrate for the formation of bile salts, and plays a role in the modulation of intracellular free calcium concentration. Taurine has the ability to activate autophagy in adipocytes[1][2][3].
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-
- HY-N0324S2
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Cholic acid- 13C is the 13C-labeled Cholic acid. Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion.
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-
- HY-N0384S3
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Homovanillic acid- 13C6, 18O is the 13C-labeled Homovanillic acid. Homovanillic acid is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency.
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-
- HY-N0437S3
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Progesterone- 13C2 is the 13C-labeled Progesterone. Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy.
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-
- HY-N0545S
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Taurocholic acid- 13C2, 15N (sodium) is the 13C- and 15N- labeled Taurocholic acid (sodium).
|
-
- HY-N0593S3
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Deoxycholic acid- 13C is the 13C-labeled Deoxycholic acid. Deoxycholic acid is specifically responsible for activating the G protein-coupled bile acid receptor TGR5 that stimulates brown adipose tissue (BAT) thermogenic activity.
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-
- HY-N0680S3
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Thiamine- 13C3 (hydrochloride) is the 13C-labeled Thiamine (hydrochloride). Thiamine hydrochloride (Thiamine chloride hydrochloride) is an essential micronutrient needed as a cofactor for many central metabolic enzymes.
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-
- HY-N0682S3
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Pyridoxine- 13C4 (hydrochloride) is the 13C-labeled Pyridoxine (hydrochloride). Pyridoxine hydrochloride (Pyridoxol; Vitamin B6) is a pyridine derivative. Pyridoxine (Pyridoxol; Vitamin B6) exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway.
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-
- HY-W008253S3
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5-Hydroxyindole-3-acetic acid- 13C6 is the 13C-labeled 5-Hydroxyindole-3-acetic acid. 5-Hydroxyindole-3-acetic acid is the main metabolite of serotonin or metanephrines, which can be used as a biomarker of neuroendocrine tumors.
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-
- HY-B0322S1
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Sulfamethoxazole- 13C6 is a 13C labeled Sulfamethoxazole. Sulfamethoxazole (Ro 4-2130) is a sulfonamide bacteriostatic antibiotic, used for bacterial infections. Sulfonamides is a competitive antagonist of para-aminobenzoic acid (PABA)[1].
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-
- HY-B0273S1
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Sulfadiazine- 13C6 is a labeled Sulfadiazine (HY-B0273). Sulfadiazine is a sulfonamide?antibiotic with antimalarial activity[1].
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-
- HY-A0181S
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1 Publications Verification
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Adenosine monophosphate- 13C10, 15N5 is the 13C-labeled and 15N-labeled Adenosine monophosphate. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction[1].
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-
- HY-79096S
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BOC-L-Phenylalanine- 13C is a 13C-labeled BOC-L-Phenylalanine. BOC-L-Phenylalanine is a derivative of Phenylalanine[1].
|
-
- HY-W000450S
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5-Aminolevulinic acid- 13C is the 13C-labeled 5-Aminolevulinic acid. 5-Aminolevulinic acid (5-ALA) is a non-protein amino acid that plays a rate-limiting role in heme biosynthesis.
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-
- HY-N0832S
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L-Histidine- 15N3 is the 15N-labeled L-Histidine. L-Histidine is an essential amino acid for infants. L-Histidine is an inhibitor of mitochondrial glutamine transport.
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-
- HY-N0470S3
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L-Lysine- 13C6, 15N2 (hydrochloride) is the 13C- and 15N-labeled L-Lysine hydrochloride. L-lysine hydrochloride is an essential amino acid for humans with various benefits including treating herpes, increasing calcium absorption, reducing diabetes-related illnesses and improving gut health.
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-
- HY-19528S1
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SAH- 13C5 is the 13C-labeled SAH. SAH (S-Adenosylhomocysteine) is an amino acid derivative and a modulartor in several metabolic pathways. It is an intermediate in the synthesis of cysteine and adenosine[1]. SAH is an inhibitor for METTL3-METTL14 heterodimer complex (METTL3-14) with an IC50 of 0.9 µM[2].
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-
- HY-N0325S
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DL-Methionine- 13C is the 13C-labeled DL-Methionine. DL-Methionine is an essential amino acid containing sulfur with oxidative stress defense effects. DL-Methionine can be used for animal natural feed. DL-Methionine also kills H. rostochiensis on potato plants[1][2][3].
|
-
- HY-N0394S3
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L-Cystine- 34S2 is the 34S-labeled L-Cystine. L-Cystine is an amino acid and intracellular thiol, which plays a critical role in the regulation of cellular processes.
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-
- HY-B0215S1
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Acetylcysteine- 15N (N-Acetylcysteine- 15N) is the 15N-labeled Acetylcysteine. Acetylcysteine (N-Acetylcysteine) is a mucolytic agent which reduces the thickness of the mucus. Acetylcysteine is a ROS inhibitor. Acetylcysteine is a cysteine precursor, prevents hemin-induced ferroptosis by neutralizing toxic lipids generated by arachidonate-dependent activity of 5-lipoxygenases. Acetylcysteine induces cell apoptosis. Acetylcysteine also has anti-influenza virus activities. In addition, Acetylcysteine is the most stable form of cysteine during drug delivery and can be used in disulfidptosis studies .
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-
- HY-13677S1
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6-Mercaptopurine- 13C2, 15N is the 13C- and 15N-labeled 6-Mercaptopurine. 6-Mercaptopurine is a purine analogue which acts as an antagonist of the endogenous purines and has been widely used as antileukemic agent and immunosuppressive agent.
|
-
- HY-15129S
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O-Phospho-L-serine- 13C3, 15N is the 13C- and 15N-labeled O-Phospho-L-serine. O-Phospho-L-serine is the immediate precursor to L-serine in the serine synthesis pathway, and an agonist at the group III mGluR receptors (mGluR4, mGluR6, mGluR7, and mGluR8); O-Phospho-L-serine also acts as a weak antagonist for mGluR1 and a potent antagonist for mGluR2[1].
|
-
- HY-N0390S10
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L-Glutamine-1,2- 13C2 is the 13C-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells[1][2].
|
-
- HY-N0390S11
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L-Glutamine-2- 13C is the 13C-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells[1][2].
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-
- HY-D0187S
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L-Glutathione reduced- 13C2, 15N is the 13C- and 15N-labeled L-Glutathione reduced. L-Glutathione reduced (GSH) is an endogenous antioxidant and is capable of scavenging oxygen-derived free radicals.
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-
- HY-I0096S
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Indole-2-carboxylic acid- 13C is the 13C-labeled Indole-2-carboxylic acid. Indole-2-carboxylic acid is a strong inhibitor of lipid peroxidation. Indole-2-carboxylic acid (I2CA) specifically and competitively inhibits the potentiation by glycine of NMDA-gated current[1][2].
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-
- HY-W015466S
-
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Acetylvaline- 15N is the 15N-labeled Acetylvaline. Acetylvaline is an endogenous metabolite[1].
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-
- HY-W134007S1
-
3 Publications Verification
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Hexadecanoate- 13C16 (potassium) is the 13C-labeled Hexadecanoate sodium. Hexadecanoate potassium can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells[1][2].
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-
- HY-100532S
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CD437- 13C6 is the 13C- and deuterium labeled CD437. CD437 is a selective Retinoic Acid Receptor γ (RARγ) agonist.
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-
- HY-113365S1
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Cholestenone- 13C is the 13C labeled Cholestenone. Cholestenone (4-Cholesten-3-one), the intermediate oxidation product of cholesterol, is metabolized primarily in the liver. Cholestenone is highly mobile in membranes and influences cholesterol flip-flop and efflux. Cholestenone may cause long-term functional defects in cells[1][2][3].
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-
- HY-113365S2
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Cholestenone- 13C2 is the 13C labeled Cholestenone. Cholestenone (4-Cholesten-3-one), the intermediate oxidation product of cholesterol, is metabolized primarily in the liver. Cholestenone is highly mobile in membranes and influences cholesterol flip-flop and efflux. Cholestenone may cause long-term functional defects in cells[1][2][3].
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-
- HY-13458S1
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Droxidopa- 13C2, 15N (hydrochloride) is deuterium labeled Droxidopa. Droxidopa(L-DOPS), the mixture of Droxidopa (w/w80%) and Pharmaceutical starch (w/w20%), acts as a proagent to the neurotransmitters norepinephrine (noradrenaline) and epinephrine (adrenaline); Droxidopa(L-DOPS) is capable of crossing the protective blood–brain barrier[1][2].
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-
- HY-137912S1
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Resveratrol-3-O-beta-D-glucuronide- 13C6 is deuterium labeled trans-Resveratrol-3-O-β-D-Glucuronide.
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-
- HY-144153S
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|
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S-(1,2-Dichlorovinyl)glutathione- 13C2, 15N is the 13C- and 15N-labeled S-(1,2-Dichlorovinyl)glutathione[1].
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-
- HY-41121S4
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Boc-L-Ala-OH- 15N is the 15N labeled Boc-L-Ala-OH.
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-
- HY-B1732S3
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DL-3-Phenylalanine- 13C-1 is the 13C labeled DL-3-Phenylalanine[1].
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-
- HY-N0322S8
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Cholesterol- 18O is the deuterium labeled Cholesterol. Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins . Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist .
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- HY-W004260S3
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Arachidic acid- 13C is the 13C labeled Arachidic acid. Arachidic acid (Icosanoic acid), a long-chain fatty acid, is present in all mammalian cells, typically esterified to membrane phospholipids, and is one of the most abundant polyunsaturated fatty acids present in human tissue .
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-
- HY-W007720S1
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Fmoc-Ser-OH- 15N is the 15N labeled Fmoc-Ser-OH.
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-
- HY-W013061S5
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Propane-1,2,3-triyl tripalmitate- 13C2 is the 13C labeled Propane-1,2,3-triyl tripalmitate. Propane-1,2,3-triyl tripalmitate is an endogenous metabolite.
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-
- HY-W014223S
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2,4-Dihydroxybenzophenone- 13C6 (Ultraviolet absorber UV-0- 13C6) is the 13C- and deuterium labeled (2,4-Dihydroxyphenyl)(phenyl)methanone[1].
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-
- HY-Y0366S4
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Lauric acid- 13C-1 is the deuterium labeled Lauric acid. Lauric acid is a middle chain-free fatty acid with strong bactericidal properties. The EC50s for P. acnes, S.aureus, S. epidermidis, are 2, 6, 4 μg/mL, respectively[1].
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-
- HY-N0229S15
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L-Alanine- 13C2, 15N is the 13C- and 15N-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.
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-
- HY-100354S
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C16-Ceramide- 13C16 is a 13C-labeled Glycine ethyl ester monohydrochloride[1].
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-
- HY-101064S
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Fmoc-leucine- 13C is a 13C-labeled Boc-Glycine[1].
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- HY-101064S1
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Fmoc-leucine- 13C6, 15N is a 15N-labeled and 13C-labled Fmoc-leucine. Fmoc-leucine is a selective PPARγ modulator. Fmoc-leucine activates PPARγ with a lower potency but a similar maximal efficacy than rosiglitazone. Fmoc-leucine improves insulin sensitivity
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- HY-101064S4
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Fmoc-leucine- 15N is a 15N-labeled and 13C-labled EIDD-1931. EIDD-1931 (Beta-d-N4-hydroxycytidine; NHC) is a novel nucleoside analog and behaves as a potent anti-virus agent. EIDD-1931 effectively inhibits the replication activity of venezuelan equine ence
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- HY-128790S1
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4-Methoxyestrone- 13C6 is a 13C-labeled 5'-Guanylic acid. 5'-Guanylic acid (5'-GMP) is involved in several metabolic disorders, including the AICA-ribosiduria pathway, adenosine deaminase deficiency, adenine phosphoribosyltransferase deficiency (aprt), and
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-
- HY-141578S
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C18:1-Ceramide- 13C18 is a 13C-labeled C16-Ceramide[1].
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-
- HY-141901S2
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Dehydroepiandrosterone- 13C3 is a 13C-labeled and deuterium labeled Dehydroepiandrosterone[1].
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-
- HY-143857S
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22:0 Lyso PC- 13C6 is a 13C-labeled and deuterium labeled 22:0 Lyso PC[1].
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-
- HY-143876S
-
1 Publications Verification
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L-Argininosuccinic acid- 13C6, 15N4 (barium, dihydrate) is a 15N-labeled and 13C-labled labeled L-Argininosuccinic acid (barium, dihydrate)[1].
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- HY-144085S
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D-Fructose-6-phosphate- 13C6 disodium x.hydrate is a 13C-labeled D-Fructose-6-phosphate disodium x.hydrate .
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-
- HY-144344S
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Benzyl(2R)-3-N,N-dibenzylamino-2-fluoropropanoate- 13C3 is a 13C-labeled and deuterium labeled Benzyl(2R)-3-N,N-dibenzylamino-2-fluoropropanoate[1].
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-
- HY-144345S
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L-GAMMA-glutamyl-L-cysteinyl-L-lysine- 13C5, 15N is a 15N-labeled and 13C-labled labeled L-GAMMA-glutamyl-L-cysteinyl-L-lysine[1].
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-
- HY-144348S
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N-[4-(2-Pyridinyl)benzoyl]glycine- 13C2, 15N is a 15N-labeled and 13C-labled labeled N-[4-(2-Pyridinyl)benzoyl]glycine[1].
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-
- HY-144418S
-
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DL-2-Amino-3-(hydroxy-amino)propionic acid- 15N is a 15N-labeled DL-2-Amino-3-(hydroxy-amino)propionic acid[1].
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-
- HY-144432S
-
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Vitamin B5- 13C3, 15N hemicalcium hemihydrate is the 13C and 15N labeled Vitamin B5 hemicalcium hemihydrate .
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- HY-146708S
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((2R,3S,4R,5R)-5-(2-Amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate- 15N4 (sodium) is a 15N-labeled ((2R,3S,4R,5R)-5-(2-Amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate (so
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- HY-41121S1
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Boc-L-Ala-OH-3- 13C is a 13C-labeled Hypoxanthine. Hypoxanthine, a purine derivative, is a potential free radical generator and could be used as an indicator of hypoxia.
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-
- HY-41121S2
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Boc-L-Ala-OH-2- 13C is a 13C-labeled H-Lys-OH.2HCl[1].
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-
- HY-76204S
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Glycine ethyl ester- 13C (hydrochloride) is a 13C-labeled Mebendazole.
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-
- HY-76204S1
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Glycine ethyl ester- 13C2 (hydrochloride) is a 13C-labeled Propham[1].
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-
- HY-79128S
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Fmoc-L-Lys (Boc)-OH- 15N2 is a 15N-labeled Fmoc-L-Lys (Boc)-OH (HY-79128). Fmoc-L-Lys (Boc)-OH is a lysine derivative .
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-
- HY-79131S
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Fmoc-Phe-OH- 13C6 is a 13C-labeled Fmoc-Ala-OH[1].
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-
- HY-79131S1
-
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Fmoc-Phe-OH- 13C9, 15N is a 15N-labeled and 13C-labled Fmoc-Ala-OH[1].
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-
- HY-79131S3
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Fmoc-Phe-OH- 15N is a 15N-labeled Propoxur.
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-
- HY-79576S2
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Estrone 3-methyl ether- 13C6 is a 13C-labeled 3-(4-Chlorophenyl)-1-methoxy-1-methylurea[1].
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-
- HY-I1111S1
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Fmoc-L-Val-OH-1- 13C is a 13C-labeled Carbaryl. Carbaryl is used chiefly as an insecticide[1].
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-
- HY-I1111S2
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Fmoc-L-Val-OH- 13C5, 15N is a 15N-labeled and 13C-labled Pirimicarb. Pirimicarb is a fast-acting selective carbamate insecticide on a wide range of crops including cereals, sugar beet, potatoes, fruits and vegetables. Pirimicarb is an AChE inhibitor and an
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-
- HY-I1111S3
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Fmoc-L-Val-OH- 13C5 is a 13C-labeled Fmoc-Gly-OH[1].
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-
- HY-I1111S4
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Fmoc-L-Val-OH- 15N is a 15N-labeled Leucomalachite green. Leucomalachite green is a triphenylmethane dye used to detect blood. Leucomalachite green, a major metabolite of malachite green, is a potential carcinogen, teratogen and mutagen[1][2].
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-
- HY-N0091S
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Hypoxanthine- 13C5, 15N4 is a 15N-labeled and 13C-labled Dansyl chloride.
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-
- HY-N0091S1
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Hypoxanthine- 13C, 15N2 is a 15N-labeled and 13C-labled Furaltadone. Furaltadone, a nitrofuran agent, has the potential for the study in infections of chickens with salmonella enteritidis. Furaltadone is inhibitory and bactericidal in vitro for staphylococci
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-
- HY-N0091S2
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Hypoxanthine- 13C5 is a 13C-labeled H-Lys-OH.2HCl[1].
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-
- HY-N0091S3
-
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Hypoxanthine- 13C2, 15N is a 15N-labeled and 13C-labled DL-Cystine[1].
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-
- HY-N0091S4
-
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Hypoxanthine- 13C2, 15N-1 is a 15N-labeled and 13C-labled 4-Hydroxyestrone[1].
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-
- HY-W002327S
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Fmoc-Asn(Trt)-OH- 13C4, 15N2 is a 15N-labeled and 13C-labled 4-(4-(tert-Butyl)-2-ethoxyphenyl)-2-(2,6-difluorophenyl)-4,5-dihydrooxazole[1].
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-
- HY-W002327S1
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L-Asparagine-N-Fmoc,N-beta-trityl- 15N2 is a 15N-labeled L-Asparagine-N-Fmoc,N-beta-trityl .
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-
- HY-W007706S
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Fmoc-Thr(tBu)-OH- 13C4, 15N is a 15N-labeled and 13C-labled 2-Acetamidobenzamide[1].
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-
- HY-W007798S
-
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Fmoc-Cys(Trt)-OH-1,2,3- 13C3, 15N is a 15N-labeled and 13C-labled Fmoc-Phe-OH[1].
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-
- HY-W007941S
-
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Fmoc-Ser(tBu)-OH- 13C3, 15N is a 15N-labeled and 13C-labled Fmoc-L-Lys (Boc)-OH[1].
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-
- HY-W008016S
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Fmoc-Tyr(tBu)-OH- 13C9, 15N is a 15N-labeled and 13C-labled Hypoxanthine. Hypoxanthine, a purine derivative, is a potential free radical generator and could be used as an indicator of hypoxia.
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-
- HY-W008371S1
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Fmoc-Met-OH- 13C5, 15N is a 15N-labeled and 13C-labled Fmoc-L-Val-OH[1].
|
-
- HY-W008621S
-
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|
|
Oleic acid- 13C (potassium) is a 13C-labeled (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-oxo-4-(tritylamino)butanoic acid[1].
|
-
- HY-W009204S4
-
|
|
|
Fmoc-Ala-OH- 13C3, 15N is a 15N-labeled and 13C-labled Fmoc-Aib-OH[1].
|
-
- HY-W009204S5
-
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|
Fmoc-Ala-OH- 13C3 is a 13C-labeled Fmoc-leucine. Fmoc-leucine is a selective PPARγ modulator. Fmoc-leucine activates PPARγ with a lower potency but a similar maximal efficacy than rosiglitazone. Fmoc-leucine improves insulin sensitivity in normal, diet-ind
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-
- HY-W009300S1
-
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|
4-Hydroxyestrone- 13C6 is a 13C-labeled Hypoxanthine. Hypoxanthine, a purine derivative, is a potential free radical generator and could be used as an indicator of hypoxia.
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-
- HY-W009762S
-
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|
L-Lysine- 13C6, 15N2 (dihydrochloride) is a 15N-labeled and 13C-labled L-Lysine dihydrochloride[1].
|
-
- HY-W009762S1
-
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|
|
L-Lysine6- 13C (dihydrochloride) is a 13C-labeled L-Lysine dihydrochloride.
|
-
- HY-W009762S6
-
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|
|
L-Lysine- 15N2 (dihydrochloride) is a 15N-labeled L-Lysine dihydrochloride[1].
|
-
- HY-W009762S7
-
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|
|
L-Lysine- 15N dihydrochloride is a 15N-labeled L-Lysine dihydrochloride[1].
|
-
- HY-W010209S
-
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|
DL-Histidine- 13C6, 15N3 N-Acetyl-S-allyl-L-cysteine
|
-
- HY-W010209S1
-
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|
DL-Histidine- 15N is a 15N-labeled Pefloxacin.
|
-
- HY-W011012S
-
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|
|
Adenosine 5'-monophosphate- 13C (disodium) is a 13C-labeled H-Lys-OH.2HCl[1].
|
-
- HY-W013780S
-
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Fmoc-Pro-OH-1- 13C is a 13C-labeled Sulfabenzamide. Sulfabenzamide (N-Sulfanilylbenzamide) is an antimicrobial agent and usually consumed in combination with Sulfathiazole and Sulfacetamide. Sulfabenzamide is effective against Gram-positive and negative ba
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-
- HY-W013780S1
-
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Fmoc-Pro-OH- 13C5, 15N is a 15N-labeled and 13C-labled Pyrimethanil. Pyrimethanil is an anilinopyrimidine and broad-spectrum contact fungicide for the control of Botrytis spp. on a wide variety of crops[1]. Pyrimethanil inhibits the biosynthesis of methioni
|
-
- HY-W013780S2
-
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|
|
Fmoc-Pro-OH- 15N is a 15N-labeled Glycine ethyl ester monohydrochloride[1].
|
-
- HY-W015339S
-
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|
|
Octanoate- 13C (sodium) is a 13C-labeled Fmoc-Gly-OH[1].
|
-
- HY-W017389S
-
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|
Xanthine- 13C, 15N2 is a 15N-labeled and 13C-labled Xanthine (HY-W017389). Xanthine is a plant alkaloid with mild stimulant activity of the central nervous system. Xanthine also acts as an intermediate product on the pathway of purine degradation .
|
-
- HY-W018386S
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|
|
3-Bromo-L-tyrosine- 13C6 (3-Bromo-Tyr- 13C6) is a 13C-labeled H-Lys-OH.2HCl[1].
|
-
- HY-W101495S
-
|
|
|
Boc-Leu-OH·H2O- 13C is a 13C-labeled γ-Tocotrienol. γ-Tocotrienol is an active form of vitamin E[1].
|
-
- HY-W134007S
-
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|
|
Hexadecanoate- 13C (potassium) is a 13C-labeled Fmoc-L-Val-OH[1].
|
-
- HY-Y0134S
-
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|
|
Fmoc-Glu(OtBu)-OH- 15N is a 15N-labeled Fmoc-L-Val-OH[1].
|
-
- HY-Y0978S2
-
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|
Boc-Glycine-2- 13C is a 13C-labeled Linuron. Linuron is a phenylurea herbicide that is widely used to control the growth of grass and weeds in various agriculture crops and in orchards. Linuron is a photosystem II inhibitor. Linuron is also a competitive a
|
-
- HY-Y0978S3
-
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|
Boc-Glycine- 13C is a 13C-labeled H-Lys-OH.2HCl[1].
|
-
- HY-Y1250S3
-
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|
Fmoc-Gly-OH- 13C is a 13C-labeled Fmoc-Phe-OH[1].
|
-
- HY-Y1250S4
-
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|
Fmoc-Gly-OH-1- 13C is a 13C-labeled Carbendazim. Carbendazim is a potent and orally active broad-spectrum benzimidazole fungicide and can be acts as a pesticide for fungal diseases research, such as Seproria, Fusarium and Sclerotina[1][3]. Carbendazim is a
|
-
- HY-Y1250S5
-
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|
Fmoc-Gly-OH- 13C2 is a 13C-labeled Fmoc-Gly-OH (HY-Y1250). Fmoc-Gly-OH (Fmoc glycine) is a Fmoc-protected glycine derivative, can be used for the synthesis of compounds .
|
-
- HY-Y1250S6
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Fmoc-Gly-OH- 13C2, 15N is a 15N-labeled and 13C-labled Crystal Violet. Crystal violet (Basic Violet 3) is a triarylmethane dye. Crystal Violet (Gentian Violet) has antiviral effects against H1N1 and also has prominent bactericidal activities.
|
-
- HY-112019
-
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|
L-Methionine- 34S is a 34S-labeled L-Methionine. L-Methionine is the L-isomer of Methionine, an essential amino acid for human development. Methionine acts as a hepatoprotectant.
|
-
- HY-B0035S2
-
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|
|
Sulfamethazine- 13C6 is a 13C-labeled n-Acetyl-s-methyl-l-cysteine[1].
|
-
- HY-Y0479AS
-
|
|
|
L-Lactic acid- 13C3 (sodium) is the 13C labeled L-Lactic acid. L-Lactic acid- 13C3 sodium can be used for lactate metabolism research[1].
|
-
- HY-112586S1
-
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|
Sulfaethoxypyridazine- 13C6 is the 13C6 labeled Sulfaethoxypyridazine. Sulfaethoxypyridazine is a sulfonamide antibacterial agent. Sulfaethoxypyridazine is a sulfonamide that is used in veterinary medicine as feedstuffs.
|
-
- HY-114750S
-
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|
Mebendazole-amine- 13C6 is the 13C6 labeled Mebendazole-amine. Mebendazole-amine is a metabolite of Mebendazole. Mebendazole is a broad-spectrum benzimidazole anti-helminthic agent.
|
-
- HY-116214S1
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Cyprodinil- 13C6 is the 13C6 labeled Cyprodinil. Cyprodinil is an anilinopyrimidine broad-spectrum fungicide that inhibits the biosynthesis of methionine in phytopathogenic fungi. Cyprodinil inhibits mycelial cell growth of B. cinerea, P. herpotrichoides, and H. oryzae on amino acid-free media (IC50s=0.44, 4.8, and 0.03 µM, respectively). Cyprodinil acts as an androgen receptor (AR) agonist (EC50=1.91 µM) in the absence of the AR agonist DHT and inhibits the androgenic effect of DHT (IC50=15.1 µM).
|
-
- HY-117275S1
-
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|
Meclofenamic acid- 13C6 is the 13C6 labeled Meclofenamic acid. Meclofenamic Acid (Meclofenamate), a non-steroidal, anti-inflammatory agent, is a highly selective fat mass and obesity-associated (FTO) enzyme inhibitor. Meclofenamic Acid competes with FTO binding for the m(6)A-containing nucleic acid. Meclofenamic acid is a non-selective gap-junction blocker.
|
-
- HY-12542S
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|
Dantrolene- 13C3 is the 13C3 labeled Dantrolene. Dantrolene (F368), a muscle relaxant, non-competitively inhibits human erythrocyte glutathione reductase. Ki and IC50 values are 111.6 μM and 52.3 μM, respectively. Dantrolene is a ryanodine receptor antagonist and Ca2+ signaling stabilizer. Dantrolene can be used for the research of muscle spasticity, malignant hyperthermia, Huntington's disease and other neuroleptic malignant syndrome.
|
-
- HY-133694S
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|
2-Aminoflubendazole- 13C6 is the 13C6 labeled 2-Aminoflubendazole. 2-Aminoflubendazole is the metabolite of Benzimidazoles. Benzimidazoles (BZ) are a class of agents with activities against fungi, protozoa, and helminthes.
|
-
- HY-138538S
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|
2-Nitrobenzaldehyde semicarbazone- 13C, 15N2-1 is the 13C, 15N labeled 2-Nitrobenzaldehyde semicarbazone. 2-Nitrobenzaldehyde Semicarbazone is a derivative of Semicarbazide. 2-Nitrobenzaldehyde Semicarbazone can be measured as a metabolite marker to detect the widely banned antibiotic Nitrofurazone.
|
-
- HY-14538S3
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|
Haloperidol- 13C6 is the 13C6 labeled Haloperidol. Haloperidol is a potent dopamine D2 receptor antagonist, widely used as an antipsychotic.
|
-
- HY-146785S
-
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|
|
1-Palmitoyl-2-hydroxy-sn-glycero-3-phosphate- 13C16 (sodium) is 13C16 labeled 1-Palmitoyl-2-hydroxy-sn-glycero-3-phosphate.
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-
- HY-N0684S3
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|
Vitamin K1- 13C6 is the 13C-labeled Vitamin K1. Vitamin K1 a naturally occurring vitamin required for blood coagulation and bone and vascular metabolism.
|
-
- HY-146944S
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|
12-PAHSA- 13C16 is 13C16 labeled 12-PAHSA.
|
-
- HY-146966S
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|
2-NP-DNSAH- 13C6 is the 13C6 labeled 2-NP-DNSAH.
|
-
- HY-146967S
-
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|
4-(3,6-Dimethylhept-3-yl)phenol- 13C6 is the 13C6 labeled 4-(3,6-Dimethylhept-3-yl)phenol.
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-
- HY-146968S
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Alloerythro-Isoxsuprine- 13C6 (hydrochloride) is the 13C6 labeled Alloerythro-Isoxsuprine (hydrochloride).
|
-
- HY-146969S
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|
Bisdesoxyquinoceton- 13C6 is the 13C6 labeled Bisdesoxyquinoceton.
|
-
- HY-146972S
-
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Zearalenone-14-O-β-glucoside- 13C6 is the 13C6 labeled Zearalenone-14-O-β-glucoside.
|
-
- HY-146975S
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|
Descyclopropyl-dicyclanil- 15N3 is the 15N3 labeled Descyclopropyl-dicyclanil.
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-
- HY-146976S
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Nifuraldezone- 15N3 is the 15N3 labeled Nifuraldezone.
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-
- HY-15036S1
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Diclofenac- 13C6 is the 13C6 labeled Diclofenac. Diclofenac is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells, and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively. Diclofenac induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade.
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-
- HY-15037S2
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Diclofenac- 13C6 (Sodium) is the 13C6 labeled Diclofenac (Sodium). Diclofenac Sodium (GP 45840) is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells, and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively. Diclofenac Sodium induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade.
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-
- HY-17453S1
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|
Salmeterol- 13C6 (xinafoate) is the 13C6 labeled Salmeterol (xinafoate). Salmeterol (GR 33343X) xinafoate is a potent and selective human β2 adrenoceptor agonist. Salmeterol shows potent stimulation of cAMP accumulation in CHO cells expressing human β2, β1 and β3 adrenoceptors with pEC50s of 9.6, 6.1, and 5.9, respectively.
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-
- HY-17596S
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Closantel- 13C6 is the 13C6 labeled Closantel. Closantel is a halogenated salicylanilide with a potent anti-parasitic activity. Closantel is a potent and highly specific Onchocerca volvulus chitinase (OvCHT1) inhibitor with an IC50 of 1.6 μM and a Ki of 468 nM. Closantel inhibits the O. volvulus L3 to L4 molt of developing.
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-
- HY-A0253S
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Cefacetrile- 13C3 is the 13C3 labeled Cefacetrile.
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-
- HY-B0213S1
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Sulfameter- 13C6 is the 13C6 labeled Sulfameter. Sulfameter (Sulfametoxydiazine; 5-Methoxysulfadiazine) is an effective long-acting sulfonamide antibiotic with antibacterial activities. Sulfameter can be used for the research of urinary tract infections and lepriasis.
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-
- HY-B0230S2
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Phenylbutazone- 13C12 is the 13C12 labeled Phenylbutazone. Phenylbutazone is an efficient reducing cofactor for the peroxidase activity of prostaglandin H synthase (PHS). Phenylbutazone, a hepatotoxin, is a nonsteroidal anti-inflammatory agent (NSAID). Phenylbutazone induces muscle blind-like protein 1 (MBNL1) expression and has the potential for ankylosing spondylitis research.
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-
- HY-B0263S1
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Thiabendazole- 13C6 is the 13C6 labeled Thiabendazole. Thiabendazole inhibites the mitochondrial helminth-specific enzyme, fumarate reductase, with anthelminthic property.
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- HY-B0335S1
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Tolfenamic acid- 13C6 is the 13C6 labeled Tolfenamic acid. Tolfenamic Acid (GEA 6414) is a non-steroidal anti-inflammatory and anti-cancer agent, selectively inhibits COX-2, with an IC50 of 13.49 μM (3.53 μg/mL) in LPS-treated (COX-2) canine DH82 monocyte/macrophage cells, but shows no effect on COX-1.
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-
- HY-B0467AS
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Amoxicillin- 13C6 is the 13C6 labeled Amoxicillin. Amoxicillin is an antibiotic with good oral absorption and broad spectrum antimicrobial activity.
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- HY-B0493S1
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Niflumic acid- 13C6 is the 13C6 labeled Niflumic acid. Niflumic acid, a Ca2+-activated Cl- channel blocker, is an analgesic and anti-inflammatory agent used in the treatment of rheumatoid arthritis.
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- HY-B0497S1
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Niclosamide- 13C6 is the 13C6 labeled Niclosamide. Niclosamide (BAY2353) is an orally bioavailable chlorinated salicylanilide, with anthelmintic and potential antineoplastic activity. Niclosamide (BAY2353) inhibits STAT3 with IC50 of 0.25 μM in HeLa cells and inhibits DNA replication in a cell-free assay.
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-
- HY-B0503S
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2-Thiouracil- 13C, 15N2 is the 13C, 15N labeled 2-Thiouracil. 2-Thiouracil (Thiouracil) is an antithyroid compound. 2-Thiouracil can function as a highly specific melanoma seeker. 2-Thiouracil is a selective inhibitor of neuronal nitric oxide synthase (nNOS) with a Ki of 20 μM.
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-
- HY-B0508S1
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Ornidazole- 13C2, 15N2 is the 13C, 15N labeled Ornidazole. Ornidazole(Ro 7-0207) is a 5-nitroimidazole derivative with antiprotozoal and antibacterial properties against anaerobic bacteria.
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-
- HY-B0526S
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Flumequine- 13C3 is the 13C3 labeled Flumequine. Flumequine (R-802) is a quinolone antibiotic, and acts as a topoisomerase II inhibitor, with an IC50 of 15 μM (3.92 μg/mL).
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-
- HY-B0688S2
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Dapsone- 13C12 is the 13C12 labeled Dapsone (HY-B0688). Dapsone (4,4′-Diaminodiphenyl sulfone) is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities. Dapsone exerts effective antileprosy activity and inhibits folate synthesis in cell extracts of M. leprae. Dapsone is used for dermatologic disorder research, including leprosy, dermatitis herpetiformis, acne vulgaris et al .
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-
- HY-B0925S
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Oxacillin- 13C6 (sodium) is the 13C6 labeled Oxacillin (sodium). Oxacillin sodium salt is a narrow-spectrum β-lactam antibiotic of the penicillin class.
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-
- HY-B0946S2
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Sulfamonomethoxine- 13C6 is the 13C6 labeled Sulfamonomethoxine. Sulfamonomethoxine is a long acting sulfonamide antibacterial agent, used in blood kinetic studies,and blocks the synthesis of folic acid by inhibiting synthetase of dihydropteroate.
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-
- HY-B0947S1
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Sulfanitran- 13C6 is the 13C labeled Sulfanitran. Sulfanitran is an antibacterial and anticoccidial agent used in poultry feeds. Sulfanitran also is a multidrug resistance protein 2 (MRP2) stimulator that can increase the affinity of MRP2 for estradiol-17-β-D-glucuronide (E217βG).
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-
- HY-B0975S
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Penicillin V- 13C6 (potassium) is the 13C6 labeled Penicillin V (potassium). Penicillin V Potassium (Phenoxymethylpenicillin potassium salt) is an orally active antibiotic. Penicillin V Potassium inhibits the growth of Streptococci, C. difficile and S. aureus. Penicillin V Potassium can be used for the research of otitis, sinusitis, pharyngitis and tonsillitis.
|
-
- HY-B1118S1
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Secnidazole- 13C2, 15N2 is the 13C2, 15N2 labeled Secnidazole. Secnidazole (RP-14539;PM-185184) is an orally active azole antibiotic with a longer half-life than metronidazole (HY-B0318). Secnidazole is against the vaginosis-associated bacteria and has the potential for bacterial vaginosis research.
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-
- HY-B1221S1
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Flufenamic acid- 13C6 is the 13C6 labeled Flufenamic acid. Flufenamic acid is a non-steroidal anti-inflammatory agent, inhibits cyclooxygenase (COX), activates AMPK, and also modulates ion channels, blocking chloride channels and L-type Ca 2+ channels, modulating non-selective cation channels (NSC), activating K+ channels. Flufenamic acid binds to the central pocket of TEAD2 YBD and inhibits both TEAD function and TEAD-YAP-dependent processes, such as cell migration and proliferation.
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-
- HY-B1267S1
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Sulfaguanidine- 13C6 is the 13C6 labeled Sulfaguanidine. Sulfaguanidine is an orally active antimicrobial agent/antibiotic of sulfonamide class. Sulfaguanidine can be used for the research of enteric infections such as bacillary dysentery.
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-
- HY-B1331S1
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Cyromazine- 13C3 is the 13C3 labeled Cyromazine. Cyromazine is a triazine insect growth regulator used as an insecticide and an acaricide. It is a cyclopropyl derivative of melamine. Cyromazine works by affecting the nervous system of the immature larval stages of certain insects.
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-
- HY-B1355AS1
-
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Oxyphenbutazone- 13C6 is the 13C6 labeled Oxyphenbutazone (HY-B1355A). Oxyphenbutazone is a phenylbutazone derivative, with anti-inflammatory effect. Oxyphenbutazone is a non-selective COX inhibitor. Oxyphenbutazone is the metabolite of Phenylbutazone (HY-B0230). Oxyphenbutazone selectively kills non-replicating Mycobaterium tuberculosis[1][2].
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-
- HY-B1436S1
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Nifuroxazide- 13C6 is the 13C6 labeled Nifuroxazide. Nifuroxazide is an effective inhibitor of STAT3, also exerts potent anti-tumor and anti-metastasis activity.
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-
- HY-B1703S
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Nifursol- 13C6 is the 13C6 labeled Nifursol. Nifursol is a potent and orally active veterinary antibiotic for the prevention of histomoniasis. Nifursol rapidly metabolizes to form the metabolic marker 3,5-dinitrosalicyclic acid hydrazide (DNSAH) which can persist for a long time. Nifursol is widely used for the research of Escherichia Gastroenteropathy in poultry, fowl and aquatic animal.
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-
- HY-B1781S
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Sulfachloropyridazine- 13C6 is the 13C6 labeled Sulfachloropyridazine. Sulfachloropyridazine is a broad spectrum sulfonamide used against both Gram-positive and Gram-negative aerobic bacteria.
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-
- HY-N7123S1
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Sulfacetamide- 13C6 is the 13C6 labeled Sulfacetamide. Sulfacetamide (Sulphacetamide), a bacteriostatic sulphonamide, is a popular antibiotic prescribed for treating ocular infections.
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-
- HY-N7398S
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2-Pentylfuran- 13C2 is the 13C2 labeled 2-Pentylfuran. 2-Pentylfuran is the compound isolated from steam volatile oils obtained from potatoes at atmospheric pressure.
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-
- HY-W010421S
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Ammelide- 13C3 is the 13C3 labeled Ammelide.
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-
- HY-W012478S
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6-Phenyl-2-thiouracil- 13C, 15N2 is the 13C, 15N labeled 6-Phenyl-2-thiouracil.
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-
- HY-W014225S
-
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3-Phenoxybenzoic acid- 13C6 is the 13C6 labeled 3-Phenoxybenzoic acid. 3-Phenoxybenzoic acid is an endogenous metabolite.
|
-
- HY-W017529S
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6-Chloro-1,3,5-triazine-2,4-diamine- 13C3 is the 13C3 labeled 6-Chloro-1,3,5-triazine-2,4-diamine.
|
-
- HY-W020772AS
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Aminoguanidine- 13C, 15N2 sulfate (1:2) is the 13C, 15N labeled Aminoguanidine sulfate (1:2).
|
-
- HY-W020772AS1
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Aminoguanidine- 13C, 15N4 sulfate (1:2) is the 13C, 15N labeled Aminoguanidine sulfate (1:2).
|
-
- HY-W020772S
-
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|
Aminoguanidine sulfate- 13C, 15N2 is the 13C, 15N labeled Aminoguanidine sulfate.
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-
- HY-W020772S1
-
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Aminoguanidine sulfate- 13C, 15N4 is the 13C, 15N labeled Aminoguanidine sulfate.
|
-
- HY-W069721S1
-
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N-Acetylsulfanilamide- 13C6 is the 13C6 labeled N-Acetylsulfanilamide.
|
-
- HY-W111879S
-
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Oxamic acid hydrazide- 15N3 is the 15N3 labeled Oxamic acid hydrazide.
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-
- HY-W156511S
-
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Diacetylsulfanilamide- 13C6 is the 13C6 labeled Diacetylsulfanilamide.
|
-
- HY-W278861S
-
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Desoxy-Mequindox- 13C6 is the 13C6 labeled Desoxy-Mequindox.
|
-
- HY-W280531S
-
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DNSAH- 13C6 is the 13C6 labeled DNSAH.
|
-
- HY-Y0674S
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Dicyandiamide- 13C2, 15N2 is the 15N2 labeled Dicyandiamide.
|
-
- HY-N0771S9
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L-Isoleucine- 13C6, 15N is 13C and 15N labeled L-isoleucine. L-isoleucine is a nonpolar hydrophobic amino acid[1]. L-Isoleucine is an essential amino acid.
|
-
- HY-B0167S1
-
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Salicylic acid- 13C6 is the 13C-labeled Salicylic acid (HY-B0167). Salicylic acid is a precursor to and a metabolite of Aspirin (HY-14654), can inhibit cyclo-oxygenase-2 (COX-2) activity[1][2].
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-
- HY-W242887S2
-
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D-Gulose- 13C is the 13C labeled (2R,3R,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal[1].
|
-
- HY-B0400AS
-
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L-Sorbitol- 13C is the 13C labeled L-Sorbitol[1].
|
-
- HY-B1659AS
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|
|
D-Glycerol-3- 13C is the 13C labeled D-Glycerol[1].
|
-
- HY-B0400AS1
-
|
|
|
L-Sorbitol- 13C-1 is the 13C labeled L-Sorbitol[1].
|
-
- HY-W145612S
-
|
|
|
D-Talitol-1- 13C is the 13C labeled D-Talitol[1].
|
-
- HY-W145652S
-
|
|
|
D-Altrose-1- 13C is the 13C labeled D(+)-Altrose[1].
|
-
- HY-W145652S1
-
|
|
|
D-Altrose-2- 13C is the 13C labeled D(+)-Altrose[1].
|
-
- HY-W012584S
-
|
|
|
L-Arabinopyranose- 13C is the 13C labeled L-Arabinopyranose[1].
|
-
- HY-W012584S1
-
|
|
|
L-Arabinopyranose- 13C-1 is the 13C labeled L-Arabinopyranose[1].
|
-
- HY-146989S
-
|
|
|
4-O-β-D-Galactopyranosyl-D-mannose- 13C is the 13C labeled 4-O-β-D-Galactopyranosyl-D-mannose[1].
|
-
- HY-116956S
-
|
|
|
D-Erythrose-1- 13C is the 13C labeled D-Erythrose[1].
|
-
- HY-116956S1
-
|
|
|
D-Erythrose-2- 13C is the 13C labeled D-Erythrose[1].
|
-
- HY-116956S2
-
|
|
|
D-Erythrose-3- 13C is the 13C labeled D-Erythrose[1].
|
-
- HY-116956S3
-
|
|
|
D-Erythrose-4- 13C is the 13C labeled D-Erythrose[1].
|
-
- HY-N7092AS
-
|
|
|
L-Fructose-1- 13C is the 13C labeled L-Fructose[1].
|
-
- HY-106950CS
-
|
|
|
Fosfructose-1- 13C (sodium) is the 13C labeled Fosfructose[1].
|
-
- HY-106950CS1
-
|
|
|
Fosfructose-2- 13C (sodium) is the 13C labeled Fosfructose[1].
|
-
- HY-106950CS3
-
|
|
|
Fosfructose-6- 13C (sodium) is the 13C labeled Fosfructose[1].
|
-
- HY-W142434S
-
|
|
|
D-Galactose- 13C-1 is the 13C labeled D-galactopyranose[1].
|
-
- HY-W039909S
-
|
|
|
Tri-O-acetyl-D-galactal- 13C is the 13C labeled Tri-O-Acetyl-D-galactose[1].
|
-
- HY-W039909S1
-
|
|
|
Tri-O-acetyl-D-galactal- 13C-1 is the 13C labeled Tri-O-Acetyl-D-galactose[1].
|
-
- HY-N6614S1
-
|
|
|
L-Galactose- 13C-1 is the 13C labeled L-Galactose[1].
|
-
- HY-141637S
-
|
|
|
2-Deoxy-2-fluoro-D-glucose- 13C is the 13C labeled 2-Deoxy-2-fluoro-D-glucose[1].
|
-
- HY-146990S
-
|
|
|
3-Deoxy-3-fluoro-D-glucose- 13C is the 13C labeled 3-Deoxy-3-fluoro-D-glucose[1].
|
-
- HY-146992S
-
|
|
|
α-D-Glucopyranosyl 1-phosphate- 13C (dicyclohexylamine, monohydrate) is the 13C labeled α-D-Glucopyranosyl 1-phosphate[1].
|
-
- HY-146993S
-
|
|
|
3-O-Methyl-D-glucose- 13C is the 13C labeled 3-O-Methyl-D-glucose[1].
|
-
- HY-34628S
-
|
|
|
3,4,6-Tri-O-acetyl-D-glucal- 13C is the 13C labeled 3,4,6-Tri-O-acetyl-D-glucal[1].
|
-
- HY-34628S1
-
|
|
|
3,4,6-Tri-O-acetyl-D-glucal- 13C-1 is the 13C labeled 3,4,6-Tri-O-acetyl-D-glucal[1].
|
-
- HY-34628S2
-
|
|
|
3,4,6-Tri-O-acetyl-D-glucal- 13C-2 is the 13C labeled 3,4,6-Tri-O-acetyl-D-glucal[1].
|
-
- HY-W008507S
-
|
|
|
(R)-2,3-Dihydroxypropanal-3- 13C is the 13C labeled (R)-2,3-Dihydroxypropanal[1].
|
-
- HY-146995S
-
|
|
|
Glycolaldehyde-1- 13C is the 13C labeled Glycolaldehyde[1].
|
-
- HY-146995S1
-
|
|
|
Glycolaldehyde-2- 13C is the 13C labeled Glycolaldehyde[1].
|
-
- HY-W242887S3
-
|
|
|
D-Gulose-1- 13C is the 13C labeled (2R,3R,4S,5R)-2,3,4,5,6-Pentahydroxyhexanal[1].
|
-
- HY-146994S
-
|
|
|
L-Idose- 13C is the 13C labeled L-Idose[1].
|
-
- HY-146994S1
-
|
|
|
L-Idose- 13C-1 is the 13C labeled L-Idose[1].
|
-
- HY-146994S2
-
|
|
|
L-Idose- 13C-2 is the 13C labeled L-Idose[1].
|
-
- HY-N0059AS
-
|
|
|
L-(+)-Lyxose- 13C is the 13C labeled L-Lyxose[1].
|
-
- HY-N0059AS1
-
|
|
|
L-(+)-Lyxose- 13C-1 is the 13C labeled L-Lyxose[1].
|
-
- HY-146996S
-
|
|
|
β-lactosyl- 13C is the 13C labeled β-lactosy[1].
|
-
- HY-W016508S1
-
|
|
|
L-(-)-Mannose- 13C-1 is the 13C labeled L-(-)-Mannose[1].
|
-
- HY-114364S
-
|
|
|
UDP-α-D-Galactose- 13C (disodium) is the 13C labeled UDP-α-D-Galactose disodium salt[1].
|
-
- HY-W338294S
-
|
|
|
2'-Deoxycytidine- 13C (monohydrate) is the 13C labeled 2'-Deoxycytidine[1].
|
-
- HY-W338294S1
-
|
|
|
2'-Deoxycytidine- 13C-2 (monohydrate) Monohydrate is the 13C labeled 2'-Deoxycytidine[1].
|
-
- HY-W338294S2
-
|
|
|
2'-Deoxyguanosine- 13C (monohydrate) Monohydrate is the 13C labeled 2'-Deoxyguanosine[1].
|
-
- HY-N0090S
-
|
|
|
Guanosine-1'- 13C Monohydrate is the deuterium labeled 2'-Deoxycytidine[1].
|
-
- HY-W007928S
-
|
|
|
1-O-Acetyl 2,3,5-tri-O-benzoyl-beta-D-ribofuranoside- 13C is the 13C labeled D-Ribulose[1].
|
-
- HY-W007928S1
-
|
|
|
1-O-Acetyl 2,3,5-tri-O-benzoyl-beta-D-ribofuranoside- 13C-1 is the 13C labeled 1-O-Acetyl-2,3,5-Tri-O-benzoyl-beta-D-Ribofuranose[1].
|
-
- HY-W145492S2
-
|
|
|
D-(+)-Talose- 13C is the 13C labeled 1-O-Acetyl-2,3,5-Tri-O-benzoyl-beta-D-Ribofuranose[1].
|
-
- HY-W145492S3
-
|
|
|
D-(+)-Talose- 13C-1 is the 13C labeled D-(+)-Talose[1].
|
-
- HY-146986S1
-
|
|
|
N-acetyl-D-talosamine- 13C is the 13C labeled L-Talose[1].
|
-
- HY-W012864S
-
|
|
|
(2S,3R)-2,3,4-Trihydroxybutanal- 13C is the 13C labeled N-acetyl-D-talosamine[1].
|
-
- HY-W012864S1
-
|
|
|
(2S,3R)-2,3,4-Trihydroxybutanal- 13C-1 is the 13C labeled (2S,3R)-2,3,4-Trihydroxybutanal[1].
|
-
- HY-W012864S2
-
|
|
|
(2S,3R)-2,3,4-Trihydroxybutanal- 13C-2 is the 13C labeled (2S,3R)-2,3,4-Trihydroxybutanal[1].
|
-
- HY-146279S
-
|
|
|
Amino-2-deoxy-D-galactose- 15N (hydrochloride) is the 15N labeled Amino-2-deoxy-D-galactose hydrochloride[1].
|
-
- HY-W015198S
-
|
|
|
4-(Trifluoromethyl)benzoic acid- 13C6 is the 13C labeled 4-(Trifluoromethyl)benzoic acid[1].
|
-
- HY-128748S
-
|
|
|
DL-Glyceraldehyde-1- 13C is the 13C labeled DL-Glyceraldehyde[1].
|
-
- HY-128748S1
-
|
|
|
DL-Glyceraldehyde-2- 13C is the 13C labeled DL-Glyceraldehyde[1].
|
-
- HY-128741S
-
|
|
|
D-Allose- 13C is the 13C labeled D-Allose. D-Allose is an endogenous metabolite[1].
|
-
- HY-128741S1
-
|
|
|
D-Allose- 13C-1 is the 13C labeled D-Allose. D-Allose is an endogenous metabolite[1].
|
-
- HY-128741S2
-
|
|
|
D-Allose- 13C-2 is the 13C labeled D-Allose. D-Allose is an endogenous metabolite[1].
|
-
- HY-N2353S
-
|
|
|
Arabinose-1- 13C is the 13C labeled Arabinose. Arabinose is an endogenous metabolite[1].
|
-
- HY-N0059S3
-
|
|
|
D-Arabinose- 13C-3 is the 13C labeled D-arabinose. D-arabinose is an endogenous metabolite[1].
|
-
- HY-N0059S
-
|
|
|
D-Arabinose- 13C is the 13C labeled D-arabinose. D-arabinose is an endogenous metabolite[1].
|
-
- HY-N0059S1
-
|
|
|
D-Arabinose- 13C-1 is the 13C labeled D-arabinose. D-arabinose is an endogenous metabolite[1].
|
-
- HY-N0059S2
-
|
|
|
D-arabinose- 13C-2 is the 13C labeled D-arabinose. D-arabinose is an endogenous metabolite[1].
|
-
- HY-128417S1
-
|
|
|
Alpha-D-glucose- 13C is the 13C labeled alpha-D-glucose. alpha-D-glucose is an endogenous metabolite[1].
|
-
- HY-N2325S
-
|
|
|
D-(+)-Cellobiose- 13C is the 13C labeled D-(+)-Cellobiose. D-(+)-Cellobiose is an endogenous metabolite[1].
|
-
- HY-N7092S4
-
|
|
|
D-Fructose-3- 13C is the 13C labeled D-Fructose. D-Fructose (D(-)-Fructose) is a naturally occurring monosaccharide found in many plants[1].
|
-
- HY-N7092S5
-
|
|
|
D-Fructose-4- 13C is the 13C labeled D-Fructose. D-Fructose (D(-)-Fructose) is a naturally occurring monosaccharide found in many plants[1].
|
-
- HY-N7092S6
-
|
|
|
D-Fructose-5- 13C is the 13C labeled D-Fructose. D-Fructose (D(-)-Fructose) is a naturally occurring monosaccharide found in many plants[1].
|
-
- HY-N7092S7
-
|
|
|
D-Fructose-6- 13C is the 13C labeled D-Fructose. D-Fructose (D(-)-Fructose) is a naturally occurring monosaccharide found in many plants[1].
|
-
- HY-33212S
-
|
|
|
D-N-Acetylgalactosamine- 13C is the 13C labeled D-N-Acetylgalactosamine. D-N-Acetylgalactosamine is an endogenous metabolite[1].
|
-
- HY-128753S3
-
|
|
|
D-Lyxose- 13C-2 is the 13C labeled D-Lyxose. D-Lyxose is an endogenous metabolite[1].
|
-
- HY-128753S4
-
|
|
|
D-Lyxose- 13C-3 is the 13C labeled D-Lyxose. D-Lyxose is an endogenous metabolite[1].
|
-
- HY-128753S5
-
|
|
|
D-Lyxose- 13C-4 is the 13C labeled D-Lyxose. D-Lyxose is an endogenous metabolite[1].
|
-
- HY-W011683S
-
|
|
|
2'-Deoxyadenosine monohydrate-1′- 13C is the 13C labeled 2'-Deoxyadenosine monohydrate. 2'-Deoxyadenosine monohydrate is a deoxyribonucleoside. A building block in the chemical synthesis[1].
|
-
- HY-W011683S1
-
|
|
|
2'-Deoxyadenosine monohydrate-2′- 13C is the 13C labeled 2'-Deoxyadenosine monohydrate. 2'-Deoxyadenosine monohydrate is a deoxyribonucleoside. A building block in the chemical synthesis[1].
|
-
- HY-W011683S2
-
|
|
|
2'-Deoxyadenosine monohydrate-3′- 13C is the 13C labeled 2'-Deoxyadenosine monohydrate. 2'-Deoxyadenosine monohydrate is a deoxyribonucleoside. A building block in the chemical synthesis[1].
|
-
- HY-W011683S3
-
|
|
|
2'-Deoxyadenosine monohydrate-5′- 13C is the 13C labeled 2'-Deoxyadenosine monohydrate. 2'-Deoxyadenosine monohydrate is a deoxyribonucleoside. A building block in the chemical synthesis[1].
|
-
- HY-77956S
-
|
|
|
Thyminose- 13C is the 13C labeled Thyminose. Thyminose is an endogenous metabolite[1].
|
-
- HY-77956S1
-
|
|
|
Thyminose- 13C-1 is the 13C labeled Thyminose. Thyminose is an endogenous metabolite[1].
|
-
- HY-77956S2
-
|
|
|
Thyminose- 13C-2 is the 13C labeled Thyminose. Thyminose is an endogenous metabolite[1].
|
-
- HY-W040240S
-
|
|
|
(3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one- 13C is the 13C labeled (3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one. (3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one is an endogenous metabolite[1].
|
-
- HY-W040240S1
-
|
|
|
(3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one- 13C-1 is the 13C labeled (3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one. (3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one is an endogenous metabolite[1].
|
-
- HY-W040240S2
-
|
|
|
(3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one- 13C-2 is the 13C labeled (3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one. (3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one is an endogenous metabolite[1].
|
-
- HY-N7092S20
-
|
|
|
D(-)-Fructose- 18O-1 is the 18O labeled D-Fructose. D-Fructose (D(-)-Fructose) is a naturally occurring monosaccharide found in many plants[1].
|
-
- HY-N7092S21
-
|
|
|
D-Fructose- 18O-2 is the 18O labeled D-Fructose. D-Fructose (D(-)-Fructose) is a naturally occurring monosaccharide found in many plants[1].
|
-
- HY-B1449S1
-
|
|
|
Uridine- 13C is the 13C labeled Uridine[1].
|
-
- HY-B1449S2
-
|
|
|
Uridine- 13C-1 is the 13C labeled Uridine[1].
|
-
- HY-B1449S3
-
|
|
|
Uridine- 13C-2 is the 13C labeled Uridine[1].
|
-
- HY-B1449S4
-
|
|
|
Uridine- 13C-3 is the 13C labeled Uridine[1].
|
-
- HY-B0389S29
-
|
|
|
D-Glucose- 18O is the 18O labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules
|
-
- HY-B0389S30
-
|
|
|
D-Glucose- 18O-1 is the 18O labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecule
|
-
- HY-B0389S31
-
|
|
|
D-Glucose- 18O-2 is the 18O labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecule
|
-
- HY-B0389S32
-
|
|
|
D-Glucose- 18O-3 is the 18O labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecule
|
-
- HY-A0132S4
-
|
|
|
N-Acetyl-D-glucosamine- 18O is the 18O labeled N-Acetyl-D-glucosamine. N-Acetyl-D-Glucosamine (N-Acetyl-2-amino-2-deoxy-D-glucose) is a monosaccharide derivative of gluc[1][2].
|
-
- HY-N0379S2
-
|
|
|
D-Mannose- 18O is the 18O labeled D-Mannose. D-Mannose is a carbohydrate, which plays an important role in human metabolism, especially in the glycosylationof specific prote[1][2].
|
-
- HY-W018772S
-
|
|
|
D-Ribose- 18O is the 18O labeled D-Ribose. D-Ribose is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose is active in protein glycati
|
-
- HY-113216S
-
|
|
|
Asymmetric dimethylarginine-d7 (hydrochloride hydrate) is the deuterium labeled Asymmetric dimethylarginine. Asymmetric dimethylarginine is an endogenous inhibitor of nitric oxide synthase (NOS), and functions as a marker of endothelial dysfunction in a num
|
-
- HY-N2840S
-
|
|
|
Allitol- 13C is the 13C labeled Allitol. Allitol is a rare natural polyol that can be used as a sweetener. Allitol is an important intermediate for the preparation of the agents which against diabetes, cancer, and viral infections, including AIDS[1]
|
-
- HY-N3686S
-
|
|
|
D-Arabitol- 13C is the 13C labeled D-Arabitol. D-Arabitol is a polyol and its accumulation may cause a neurotoxic effect in hu[1][2].
|
-
- HY-N3686S1
-
|
|
|
D-Arabitol- 13C-1 is the 13C labeled D-Arabitol. D-Arabitol is a polyol and its accumulation may cause a neurotoxic effect in hu[1][2].
|
-
- HY-N3686S2
-
|
|
|
D-Arabitol- 13C-2 is the 13C labeled D-Arabitol. D-Arabitol is a polyol and its accumulation may cause a neurotoxic effect in hu[1][2].
|
-
- HY-Y0418S
-
|
|
|
Dulcite- 13C is the 13C labeled Dulcite. Dulcite is a sugar alcohol with a slightly sweet taste which is a metabolic breakdown product of galact[1][2].
|
-
- HY-Y0418S1
-
|
|
|
Dulcite- 13C-1 is the 13C labeled Dulcite. Dulcite is a sugar alcohol with a slightly sweet taste which is a metabolic breakdown product of galact[1][2].
|
-
- HY-Y0418S2
-
|
|
|
Dulcite- 13C-2 is the 13C labeled Dulcite. Dulcite is a sugar alcohol with a slightly sweet taste which is a metabolic breakdown product of galact[1][2].
|
-
- HY-Y0418S3
-
|
|
|
Dulcite- 13C-3 is the 13C labeled Dulcite. Dulcite is a sugar alcohol with a slightly sweet taste which is a metabolic breakdown product of galact[1][2].
|
-
- HY-B0400S2
-
|
|
|
D-Sorbitol- 13C-1 is the 13C labeled D-Sorbitol. D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and dietary
|
-
- HY-B0400S3
-
|
|
|
D-Sorbitol- 13C-2 is the 13C labeled D-Sorbitol. D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and dietary
|
-
- HY-N0538S
-
|
|
|
Xylitol-1- 13C is the 13C labeled Xylit[1][2].
|
-
- HY-N0538S1
-
|
|
|
Xylitol-2- 13C is the 13C labeled Xylit[1][2].
|
-
- HY-N0538S2
-
|
|
|
Xylitol-5- 13C is the 13C labeled Xylit[1][2].
|
-
- HY-N1480S
-
|
|
|
(-)-Fucose- 13C is the 13C labeled (-)-Fucose. (-)-Fucose is classified as a member of the hexoses, plays a role in A and B blood group antigen substructure determination, selectin-mediated leukocyte-endothelial adhesion, and host-microbe interacti[1]
|
-
- HY-N1480S1
-
|
|
|
(-)-Fucose- 13C-1 is the 13C labeled (-)-Fucose. (-)-Fucose is classified as a member of the hexoses, plays a role in A and B blood group antigen substructure determination, selectin-mediated leukocyte-endothelial adhesion, and host-microbe interacti[
|
-
- HY-N1480S2
-
|
|
|
(-)-Fucose- 13C-2 is the 13C labeled (-)-Fucose. (-)-Fucose is classified as a member of the hexoses, plays a role in A and B blood group antigen substructure determination, selectin-mediated leukocyte-endothelial adhesion, and host-microbe interacti[
|
-
- HY-N1480S3
-
|
|
|
(-)-Fucose- 13C-3 is the 13C labeled (-)-Fucose. (-)-Fucose is classified as a member of the hexoses, plays a role in A and B blood group antigen substructure determination, selectin-mediated leukocyte-endothelial adhesion, and host-microbe interacti[
|
-
- HY-139312S
-
|
|
|
L-Mannitol-1- 13C is the 13C labeled L-Mannitol. L-mannitol is a compound can be used for the compound sweetener synthesis[1][2].
|
-
- HY-113075S
-
|
|
|
1,5-Anhydrosorbitol- 13C is the 13C labeled 1,5-Anhydrosorbitol. 1,5-Anhydrosorbitol is a short-term marker for glycemic cont[1][2].
|
-
- HY-113143AS
-
|
|
|
Galactose 1-phosphate- 13C (potassium) is the 13C labeled Galactose 1-phosphate Potassium salt. Galactose 1-phosphate Potassium salt is is an intermediate in the galactose metabolism and nucleotide sug[1][2].
|
-
- HY-113143AS1
-
|
|
|
Galactose 1-phosphate- 13C-1 (potassium) is the 13C labeled Galactose 1-phosphate Potassium salt. Galactose 1-phosphate Potassium salt is is an intermediate in the galactose metabolism and nucleotide sug[1][2].
|
-
- HY-15926S
-
|
|
|
ONPG- 13C is the 13C labeled ONPG. ONPG is a colorimetric and spectrophotometric substrate for detection of β-galactosidase activit[1][2].
|
-
- HY-A0132S1
-
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N-Acetyl-D-glucosamine- 13C is the 13C labeled N-Acetyl-D-glucosamine. N-Acetyl-D-Glucosamine (N-Acetyl-2-amino-2-deoxy-D-glucose) is a monosaccharide derivative of gluc[1][2].
|
-
- HY-A0132S2
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N-Acetyl-D-glucosamine- 13C-1 is the 13C labeled N-Acetyl-D-glucosamine. N-Acetyl-D-Glucosamine (N-Acetyl-2-amino-2-deoxy-D-glucose) is a monosaccharide derivative of gluc[1][2].
|
-
- HY-A0132S3
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N-Acetyl-D-glucosamine-2- 13C is the 13C labeled N-Acetyl-D-glucosamine. N-Acetyl-D-Glucosamine (N-Acetyl-2-amino-2-deoxy-D-glucose) is a monosaccharide derivative of gluc[1][2].
|
-
- HY-W010042S
-
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L-Glucose- 13C is the 13C labeled L-Glucose. L-Glucose (L-(-)-Glucose) is an enantiomer of D-glucose. L-Glucose can promote food intake[1][2].
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-
- HY-W010042S1
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L-Glucose- 13C-1 is the 13C labeled L-Glucose. L-Glucose (L-(-)-Glucose) is an enantiomer of D-glucose. L-Glucose can promote food intake[1][2].
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-
- HY-A0132S5
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N-Acetyl-D-glucosamine- 13C-3 is the 13C labeled N-Acetyl-D-glucosamine. N-Acetyl-D-Glucosamine (N-Acetyl-2-amino-2-deoxy-D-glucose) is a monosaccharide derivative of gluc[1][2].
|
-
- HY-I0301S
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D-(+)-Glucono-1,5-lactone-1- 13C is the 13C labeled D-(+)-Glucono-1,5-lactone. D-(+)-Glucono-1,5-lactone is a polyhydroxy (PHA) that is capable of metal chelating, moisturizing and antioxidant activ[1][2].
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-
- HY-W010042S2
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L-Glucose- 13C-2 is the 13C labeled L-Glucose. L-Glucose (L-(-)-Glucose) is an enantiomer of D-glucose. L-Glucose can promote food intake[1][2].
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-
- HY-N0379S5
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D-Mannose- 13C is the 13C labeled D-Mannose. D-Mannose is a carbohydrate, which plays an important role in human metabolism, especially in the glycosylationof specific prote[1][2].
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-
- HY-N0379S6
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D-Mannose- 13C-1 is the 13C labeled D-Mannose. D-Mannose is a carbohydrate, which plays an important role in human metabolism, especially in the glycosylationof specific prote[1][2].
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-
- HY-N0379S7
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D-Mannose- 13C-2 is the 13C labeled D-Mannose. D-Mannose is a carbohydrate, which plays an important role in human metabolism, especially in the glycosylationof specific prote[1][2].
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-
- HY-N0379S8
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D-Mannose- 13C-3 is the 13C labeled D-Mannose. D-Mannose is a carbohydrate, which plays an important role in human metabolism, especially in the glycosylationof specific prote[1][2].
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-
- HY-N0379S9
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D-Mannose- 13C-4 is the 13C labeled D-Mannose. D-Mannose is a carbohydrate, which plays an important role in human metabolism, especially in the glycosylationof specific prote[1][2].
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-
- HY-N0379S10
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D-Mannose- 13C-5 is the 13C labeled D-Mannose. D-Mannose is a carbohydrate, which plays an important role in human metabolism, especially in the glycosylationof specific prote[1][2].
|
-
- HY-B1092AS
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|
Gluconate-1- 13C (sodium) is the 13C labeled Gluconate sodi[1][2].
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-
- HY-112174S
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UDP-GlcNAc- 13C (disodium) is the 13C labeled UDP-GlcNAc Disodium Salt. UDP-GlcNAc Disodium Salt (UDP-α-D-N-Acetylglucosamine Disodium Salt) is a donor substrate of O-GlcNAc transferase (O[1][2].
|
-
- HY-D0186S
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2'-Deoxyuridine-1′- 13C is the 13C labeled 2'-Deoxyuridine. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxud[1]
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-
- HY-D0186S1
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2'-Deoxyuridine-2′- 13C is the 13C labeled 2'-Deoxyuridine. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxud[1]
|
-
- HY-D0186S2
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2'-Deoxyuridine-3′- 13C is the 13C labeled 2'-Deoxyuridine. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxud[1]
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-
- HY-D0186S3
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2'-Deoxyuridine-5′- 13C is the 13C labeled 2'-Deoxyuridine. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxud[1]
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-
- HY-W009444S1
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5-Methyluridine-1′- 13C is the 13C labeled 5-Methyluridine. 5-Methyluridine is a is an endogenous methylated nucleoside found in human flu[1][2].
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-
- HY-W009444S2
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5-Methyluridine-2′- 13C is the 13C labeled 5-Methyluridine. 5-Methyluridine is a is an endogenous methylated nucleoside found in human flu[1][2].
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-
- HY-W009444S3
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5-Methyluridine-3′- 13C is the 13C labeled 5-Methyluridine. 5-Methyluridine is a is an endogenous methylated nucleoside found in human flu[1][2].
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-
- HY-W009444S4
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5-Methyluridine-5′- 13C is the 13C labeled 5-Methyluridine. 5-Methyluridine is a is an endogenous methylated nucleoside found in human flu[1][2].
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-
- HY-W018772S1
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D-Ribose- 13C is the 13C labeled D-Ribose. D-Ribose is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose is active in protein glycati
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-
- HY-W018772S2
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D-Ribose- 13C-1 is the 13C labeled D-Ribose. D-Ribose is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose is active in protein glyca
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-
- HY-W018772S3
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D-Ribose- 13C-2 is the 13C labeled D-Ribose. D-Ribose is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose is active in protein glyca
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-
- HY-W018772S4
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D-Ribose- 13C-3 is the 13C labeled D-Ribose. D-Ribose is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose is active in protein glyca
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-
- HY-W018772S5
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D-Ribose- 13C-4 is the 13C labeled D-Ribose. D-Ribose is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose is active in protein glyca
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-
- HY-W008351S
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L-Ribose- 13C is the 13C labeled L-Ribose. L-Ribose, a non-naturally occurring pentose, is an ideal starting material for use in synthesizing L-nucleosides analogues. Many anticancer and antiviral agents are synthesized based on a backbone of L-Ribose and i
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-
- HY-42680S
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D-Tagatose- 13C is the 13C labeled D-Tagatose. D-Tagatose (D-(-)-Tagatose) is a rare monosaccharide found in nature with prebiotic characteristics. D-Tagatose is as a substitute for sucrose and a low-calorie sweetener in foodstuffs such as gum, fruit juice
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-
- HY-42680S1
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D-Tagatose- 13C-1 is the 13C labeled D-Tagatose. D-Tagatose (D-(-)-Tagatose) is a rare monosaccharide found in nature with prebiotic characteristics. D-Tagatose is as a substitute for sucrose and a low-calorie sweetener in foodstuffs such as gum, fruit jui
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-
- HY-W010256S
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D-Xylulose-1- 13C is the 13C labeled D-Xylulose. D-xylulose is a precursor of the pentiol D-arabi[1][2].
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-
- HY-W010256S1
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D-Xylulose-2- 13C is the 13C labeled D-Xylulose. D-xylulose is a precursor of the pentiol D-arabi[1][2].
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-
- HY-78139S
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L-Xylose-1- 13C is the 13C labeled L-Xylose. L-Xylose (L-(-)-Xylose) is the levo-isomer of Xylose. Xylose is classified as a monosaccharide of the aldopentose type[1][2].
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-
- HY-78139S1
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L-Xylose-2- 13C is the 13C labeled L-Xylose. L-Xylose (L-(-)-Xylose) is the levo-isomer of Xylose. Xylose is classified as a monosaccharide of the aldopentose type[1][2].
|
-
- HY-78139S2
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L-Xylose-5- 13C is the 13C labeled L-Xylose. L-Xylose (L-(-)-Xylose) is the levo-isomer of Xylose. Xylose is classified as a monosaccharide of the aldopentose type[1][2].
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-
- HY-A0132S7
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N-Acetyl-D-glucosamine- 15N is the 15N labeled N-Acetyl-D-glucosamine. N-Acetyl-D-Glucosamine (N-Acetyl-2-amino-2-deoxy-D-glucose) is a monosaccharide derivative of gluc[1][2].
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-
- HY-A0132S8
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N-Acetyl-D-glucosamine- 13C, 15N is the 13C and 15N labeled N-Acetyl-D-glucosamine. N-Acetyl-D-Glucosamine (N-Acetyl-2-amino-2-deoxy-D-glucose) is a monosaccharide derivative of gluc[1][2].
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-
- HY-A0132S9
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N-Acetyl-D-glucosamine- 13C3, 15N is the 13C and 15N labeled N-Acetyl-D-glucosamine. N-Acetyl-D-Glucosamine (N-Acetyl-2-amino-2-deoxy-D-glucose) is a monosaccharide derivative of gluc[1][2].
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-
- HY-A0132S10
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N-Acetyl-D-glucosamine- 13C2, 15N is the 13C and 15N labeled N-Acetyl-D-glucosamine. N-Acetyl-D-Glucosamine (N-Acetyl-2-amino-2-deoxy-D-glucose) is a monosaccharide derivative of gluc[1][2].
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-
- HY-A0132S11
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N-Acetyl-D-glucosamine- 13C, 15N-1 is the 13C and 15N labeled N-Acetyl-D-glucosamine. N-Acetyl-D-Glucosamine (N-Acetyl-2-amino-2-deoxy-D-glucose) is a monosaccharide derivative of gluc[1][2].
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-
- HY-B0400S15
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D-Sorbitol- 18O-1 is the 18O labeled D-Sorbitol. D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and dietary
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-
- HY-B1659S1
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Glycerol- 13C is the 13C labeled Glycerol. Glycerol is used in sample preparation and gel formation for polyacrylamide gel electrophoresis[1][2][3][4].
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- HY-B1659S2
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Glycerol- 13C-1 is the 13C labeled Glycerol. Glycerol is used in sample preparation and gel formation for polyacrylamide gel electrophoresis[1][2][3][4].
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- HY-W145584S
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D-Iditol- 13C is the 13C labeled D-Iditol. D-Iditol is a fungal metabolite, a sugar alcohol that accumulates in galactokinase deficiency. D-Iditol may have potential antitumour activity[1][2][3].
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-
- HY-N0378S1
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D-Mannitol- 13C is the 13C labeled D-Mannitol[1][2][3][4].
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-
- HY-100582S
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Ribitol-1- 13C is the 13C labeled Ribitol. Ribitol is a crystalline pentose alcohol formed by the reduction of ribose. Enhancing the flux of D-glucose to the pentose phosphate pathway in Saccharomyces cerevisiae for the production of D-ribose and ribitol .
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-
- HY-100582S1
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Ribitol-2- 13C is the 13C labeled Ribitol. Ribitol is a crystalline pentose alcohol formed by the reduction of ribose. Enhancing the flux of D-glucose to the pentose phosphate pathway in Saccharomyces cerevisiae for the production of D-ribose and ribitol
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-
- HY-100582S2
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Ribitol-3- 13C is the 13C labeled Ribitol. Ribitol is a crystalline pentose alcohol formed by the reduction of ribose. Enhancing the flux of D-glucose to the pentose phosphate pathway in Saccharomyces cerevisiae for the production of D-ribose and ribitol
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-
- HY-100582S3
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Ribitol-5- 13C is the 13C labeled Ribitol. Ribitol is a crystalline pentose alcohol formed by the reduction of ribose. Enhancing the flux of D-glucose to the pentose phosphate pathway in Saccharomyces cerevisiae for the production of D-ribose and ribitol
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-
- HY-N0378S3
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D-Mannitol-2- 13C is the 13C labeled D-Mannitol.
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-
- HY-B0166S2
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L-Ascorbic acid- 13C-1 is the 13C labeled L-Ascorbic acid. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen
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- HY-B0166S3
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L-Ascorbic acid- 13C-2 is the 13C labeled L-Ascorbic acid. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen
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- HY-B0166S4
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L-Ascorbic acid- 13C-3 is the 13C labeled L-Ascorbic acid. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen
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- HY-B0166S5
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L-Ascorbic acid- 13C-4 is the 13C labeled L-Ascorbic acid. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collag
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- HY-42682S1
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D(+)-Galactosamine- 13C (hydrochloride) is the 13C labeled D(+)-Galactosamine hydrochloride. D(+)-Galactosamine (D-Galactosamine) hydrochloride, which is an established experimental toxin, primarily causes liver injury by the generation of free radicals and
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- HY-N0210S
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D-Galactose- 13C is the 13C labeled D-Galactose. D-Galactose is a natural aldohexose and C-4 epimer of glucose[1][2][3][4].
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- HY-N0210S1
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D-Galactose- 13C-2 is the 13C labeled D-Galactose. D-Galactose is a natural aldohexose and C-4 epimer of glucose[1][2][3][4].
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-
- HY-N0210S2
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D-Galactose- 13C-3 is the 13C labeled D-Galactose. D-Galactose is a natural aldohexose and C-4 epimer of glucose[1][2][3][4].
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-
- HY-N0210S3
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D-Galactose- 13C-4 is the 13C labeled D-Galactose. D-Galactose is a natural aldohexose and C-4 epimer of glucose[1][2][3][4].
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-
- HY-N0210S4
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D-Galactose- 13C-5 is the 13C labeled D-Galactose. D-Galactose is a natural aldohexose and C-4 epimer of glucose[1][2][3][4].
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- HY-N0733S
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Glucosamine- 13C (hydrochloride) is the 13C labeled Glucosamine hydrochloride. Glucosamine hydrochloride (D-Glucosamine hydrochloride) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a
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-
- HY-13966S4
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2-Deoxy-D-glucose- 13C-1 is the 13C labeled 2-Deoxy-D-glucose. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase[1][2].
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-
- HY-13966S2
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2-Deoxy-D-glucose- 13C is the 13C labeled 2-Deoxy-D-glucose. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase[1][2].
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- HY-N0733S1
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Glucosamine-2- 13C (hydrochloride) is the 13C labeled Glucosamine hydrochloride. Glucosamine hydrochloride (D-Glucosamine hydrochloride) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as
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- HY-N0733S2
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Glucosamine- 13C, 15N (hydrochloride) is the 13C and 15N labeled Glucosamine hydrochloride. Glucosamine hydrochloride (D-Glucosamine hydrochloride) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, i
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- HY-N0733S3
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Glucosamine-6- 13C (hydrochloride) is the 13C labeled Glucosamine hydrochloride. Glucosamine hydrochloride (D-Glucosamine hydrochloride) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as
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- HY-U00462S
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D-Mannoheptulose- 13C is the 13C labeled D-Mannoheptulose. D-Mannoheptulose is a major non-structural carbohydrate in avocado. D-mannoheptulose is a specific inhibitor of D-glucose phosphorylation. D-Mannoheptulose can block insulin release and utilization
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- HY-128850S1
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N-Acetyl-D-mannosamine- 13C is the 13C labeled N-Acetyl-D-mannosamine. N-Acetyl-D-mannosamine (ManNAc) is an essential precursor of N-acetylneuraminic acid (NeuAc), the specific monomer of bacterial capsular polysialic acid (PA)[1][2]
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- HY-128850S2
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N-Acetyl-D-mannosamine- 13C-1 is the 13C labeled N-Acetyl-D-mannosamine. N-Acetyl-D-mannosamine (ManNAc) is an essential precursor of N-acetylneuraminic acid (NeuAc), the specific monomer of bacterial capsular polysialic acid (PA)[1][2]
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-
- HY-I0400S
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N-Acetylneuraminic acid- 13C is the 13C labeled N-Acetylneuraminic acid.
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-
- HY-I0400S1
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N-Acetylneuraminic acid- 13C-1 is the 13C labeled N-Acetylneuraminic acid.
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-
- HY-I0400S2
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N-Acetylneuraminic acid- 13C-2 is the 13C labeled N-Acetylneuraminic acid.
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-
- HY-I0400S3
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N-Acetylneuraminic acid- 13C-3 is the 13C labeled N-Acetylneuraminic acid.
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- HY-N7032S
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Uridine 5′-diphosphoglucose- 13C (disodium) is the 13C labeled Uridine 5′-diphosphoglucose disodium salt. Uridine 5′-diphosphoglucose disodium salt (UDP-D-Glucose disodium salt) is the precursor of glucose-containing oligosaccharides, polysaccharides, glycop
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- HY-B0228S4
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Adenosine-1′- 13C is the 13C labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiolo
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- HY-B0228S2
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Adenosine-2′- 13C is the 13C labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiolo
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- HY-B0228S3
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Adenosine-3′- 13C is the 13C labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiolo
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- HY-B0228S5
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Adenosine- 13C is the 13C labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology,
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- HY-B0158S1
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Cytidine- 13C is the 13C labeled Cytidine. Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catecholamine
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- HY-N1150S4
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Thymidine- 13C-2 is the 13C labeled Thymidine. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication[1]
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- HY-N1150S5
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Thymidine-2′- 13C is the 13C labeled Thymidine. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication[1]<
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-
- HY-N1150S2
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Thymidine- 13C is the 13C labeled Thymidine. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication[1]
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- HY-N1150S3
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Thymidine- 13C-1 is the 13C labeled Thymidine. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication[1]
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-
- HY-B0158S2
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Cytidine- 13C-1 is the 13C labeled Cytidine. Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catecholami
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-
- HY-N0092S1
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Inosine- 13C is the 13C labeled Inosine. Inosine is an endogenous purine nucleoside produced by catabolism of adenosine. Inosine has anti-inflammatory, antinociceptive, immunomodulatory and neuroprotective effects. Inosine is an agonist for adenosine A1 (A1R) and A2A (A2AR) receptors .
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- HY-N1420AS
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Rhamnose- 13C (monohydrate) is the 13C labeled Rhamnose monohydrate. Rhamnose monohydrate (L-Rhamnose monohydrate) is a monosaccharide found in plants and bacteria. Rhamnose monohydrate-conjugated immunogens is used in immunotherapies. Rhamnose monohydrate c
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- HY-N1420AS2
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Rhamnose- 13C-2 (monohydrate) is the 13C labeled Rhamnose monohydrate. Rhamnose monohydrate (L-Rhamnose monohydrate) is a monosaccharide found in plants and bacteria. Rhamnose monohydrate-conjugated immunogens is used in immunotherapies. Rhamnose monohydrate
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- HY-N0537S2
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Xylose-1- 13C is the 13C labeled Xylose.
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-
- HY-N0537S3
-
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Xylose-2- 13C is the 13C labeled Xylose.
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-
- HY-N0537S4
-
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Xylose-5- 13C is the 13C labeled Xylose.
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-
- HY-N0537S5
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Xylose-3- 13C is the 13C labeled Xylose.
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-
- HY-N0537S6
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Xylose-4- 13C is the 13C labeled Xylose.
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-
- HY-N0733S4
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Glucosamine- 15N (hydrochloride) is the 15N labeled Glucosamine hydrochloride. Glucosamine hydrochloride (D-Glucosamine hydrochloride) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a
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- HY-N0733S5
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Glucosamine- 13C6, 15N (hydrochloride) is the 13C and 15N labeled Glucosamine hydrochloride. Glucosamine hydrochloride (D-Glucosamine hydrochloride) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids,
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- HY-128850S5
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N-Acetyl-D-mannosamine- 15N is the 15N labeled N-Acetyl-D-mannosamine. N-Acetyl-D-mannosamine (ManNAc) is an essential precursor of N-acetylneuraminic acid (NeuAc), the specific monomer of bacterial capsular polysialic acid (PA)[1][2]
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-
- HY-N0537S
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Xylose- 18O is the 18O labeled Xylose.
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-
- HY-112251S
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D-Lin-MC3-DMA- 13C3 is the 13C labeled D-Lin-MC3-DMA. D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle[1][2].
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- HY-108226S1
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Regorafenib N-oxide and N-desmethyl (M5)- 13C6 is the 13C-labeled Regorafenib N-oxide and N-desmethyl (M5)[1].
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-
- HY-108872S
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Water- 18O is the 18O-labeled Water .
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- HY-W010382S
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Oxaloacetic acid- 13C4 is the 13C-labeled Oxaloacetic acid. Oxaloacetic acid (2-Oxosuccinic acid) is a metabolic intermediate involved in several ways, such as citric acid cycle, gluconeogenesis, the urea cycle, the glyoxylate cycle, amino acid synthesis, and fatty acid synthesis[1][2][3].
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-
- HY-Y1269S
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-
- HY-B0228S10
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(R)-3-Hydroxybutanoic acid- 13C2 (sodium) is the 13C labeled (R)-3-Hydroxybutanoic acid (sodium) (HY-W015851). (R)-3-Hydroxybutanoic acid (sodium) is a metabolite converted from acetoacetic acid catalyzed by 3-hydroxybutyrate dehydrogenase. (R)-3-Hydroxybutanoic acid sodium can function as a nutrition source, and as a precursor for vitamins, antibiotics and pheromones[1][2][3].
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- HY-W010452S1
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3-Hydroxybutyric acid- 13C4 (sodium) is the 13C labeled 3-Hydroxybutyric acid sodium (HY-W010452). 3-Hydroxybutyric acid sodium is a metabolite that is elevated in type I diabetes, and can modulate the properties of membrane lipids[1].
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- HY-W010452S2
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3-Hydroxybutyric acid- 13C2 (sodium) is the 13C labeled 3-Hydroxybutyric acid sodium (HY-W010452). 3-Hydroxybutyric acid sodium is a metabolite that is elevated in type I diabetes, and can modulate the properties of membrane lipids[1].
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- HY-B0495S4
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Lamotrigine- 13C3 is the 13C-labeled Lamotrigine. Lamotrigine (BW430C) is a potent and orally active anticonvulsant or antiepileptic agent. Lamotrigine selectively blocks voltage-gated Na+ channels, stabilizing presynaptic neuronal membranes and inhibiting glutamate release. Lamotrigine can be used for the research of epilepsy, focal seizure, et al[1][2].
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- HY-15398S4
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Vitamin D3- 13C5 is the deuterium labeled Vitamin D3 (HY-15398). Vitamin D3 (Cholecalciferol) is a naturally occuring form of vitamin D. Vitamin D3 induces cell differentiation and prevents proliferation of cancer cells[1][2].
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-
- HY-B0853S
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(Rac)-Paclobutrazol- 15N3 is the 15N-labeled Rac-Paclobutrazol[1].
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-
- HY-N6625S
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Chlorothalonil- 13C2 is the 13C-labeled Chlorothalonil. Chlorothalonil is a broad spectrum fungicide and is effective in protecting plants against fungal diseases caused mainly by Phytophthora infestans and Alternaria solani. Chlorothalonil is used for controlling of fungal foliar diseases of vegetables and crops[1][2].
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-
- HY-125296S
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Fipronil sulfone- 13C6 is the 13C-labeled Fipronil sulfone[1].
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-
- HY-B0822S1
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Fipronil- 13C6 is the 13C-labeled Fipronil. Fipronil is an insecticide that acts as a selective antagonist of insect GABA receptors (IC50s = 30 nM and 1,600 nM for cockroach and rat receptors, respectively). Fipronil also inhibits desensitizing and non-desensitizing glutamate-induced chloride currents in cockroach neurons (IC50s = 800 nM and 10 nM, respectively). Fipronil induces activity of the cytochrome P450 (CYP) isoforms CYP1A1/2, CYP2B1/2, and CYP3A1/2 in isolated rat liver microsomes.
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-
- HY-B2225AS
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Starch from potato- 13C12 is the 13C-labeled Starch from potato[1].
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- HY-W012835S2
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4-Methylanisole- 13C is the 13C-labeled 4-Methylanisole. 4-Methylanisole (4-Methoxytoluene) is food flavoring agent and can be naturally found in Ylang Ylang fragrance oil[1].
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-
- HY-152039S1
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6PPD-quinone- 13C6 is the 13C labeled 6PPD-quinone[1].
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-
- HY-N0172S
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Caffeic acid- 13C3 is an 13C labeled caffeic acid. Caffeic acid is a phytonutrient belonging to the flavonoids. Caffeic acid and its derivatives, are potential antimicrobial agents, chronic infection induced by microbes such as bacteria, fungi, and viruses[1].
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- HY-N0210S16
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D-Galactose- 13C6 is the deuterium labeled D-Galactose (HY-N0210). D-Galactose is a natural aldohexose and C-4 epimer of glucose[1][2].
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- HY-101541S1
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Docosahexaenoic acid- 13C22 methyl ester is the 13C22 labeled Docosahexaenoic acid methyl ester (HY-101541)[1].
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-
- HY-113295S
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Salicyluric acid- 13C2, 15N is the 13C2 ans 15N labeled Salicyluric acid (HY-113295)[1].
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-
- HY-136648S
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2'-Deoxyadenosine-5'-triphosphate- 13C10, 15N5 (tetraammonia) is the 13C10 ans 15N5 labeled 2'-Deoxyadenosine-5'-triphosphate (HY-136648)[1].
|
-
- HY-16637S4
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Folic acid- 15N, 13C5 is the 13C5 and 15N labeled Folic acid (HY-16637) .
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-
- HY-18341S3
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L-Thyroxine- 13C6, 15N is the 13C6 ans 15N labeled L-Thyroxine (HY-18341)[1].
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- HY-N0092S2
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Inosine- 13C5 is the 13C5 labeled Inosine (HY-N0092). Inosine is an endogenous purine nucleoside produced by catabolism of adenosine. Inosine has anti-inflammatory, antinociceptive, immunomodulatory and neuroprotective effects. Inosine is an agonist for adenosine A1 (A1R) and A2A (A2AR) receptors .
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- HY-W013378S3
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Carbamazepine 10,11-epoxide- 13C, 15N is the 13C and 15N labeled Carbamazepine 10,11-epoxide (HY-W013378)[1].
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-
- HY-W013378S4
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Carbamazepine 10,11-epoxide- 13C is the 13C labeled Carbamazepine 10,11-epoxide (HY-W013378)[1].
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- HY-W013378S5
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Carbamazepine 10,11-epoxide- 13C-1 is the 13C labeled Carbamazepine 10,11-epoxide (HY-W013378)[1].
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- HY-W357090S
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L-Idose- 13C-3 is the 13C labeled L-Idose (HY-W357090)[1].
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-
- HY-Y1069S3
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(S)-Malic acid- 13C4 is the 13C labeled S-Malic acid (HY-Y1069)[1].
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- HY-A0070AS2
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Liothyronine-13C6-1 is a 13C-labeled Liothyronine. Liothyronine is a potent thyroid hormone receptors TRα and TRβ agonist with Kis of 2.33 nM for hTRα and hTRβ, respectively .
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- HY-B0445S
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NAD+-13C5 (ammonium) is the 13C labled NAD+ (HY-B0445), with an ammonium .
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-
- HY-A0130S
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Sulfalene- 13C6 is the 13C6 labeled Sulfalene. Sulfalene (Sulfametopyrazine) is an antimalarial agent. Sulfalene is also a long-acting sulfonamide antibacterial .
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-
- HY-N0667S7
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L-Asparagine-13C4,15N2 ((-)-Asparagine-13C4,15N2) is the 13C and 15N-labeled L-Aspartic acid. L-Aspartic acid is an amino acid, shown to be a suitable pro-agent for colon-specific drug delivery .
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- HY-N0610AS2
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Cinnamic acid- 13C3 (3-Phenylacrylic acid- 13C3) is the 13C labeled Cinnamic acid (HY-N0610A). Cinnamic acid has potential use in cancer intervention, with IC50s of 1-4.5 mM in glioblastoma, melanoma, prostate and lung carcinoma cells .
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- HY-10163S2
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Dabigatran- 13C6 is the 13C labeled Dabigatran[1]. Dabigatran (BIBR 953), an oral anticoagulant, is a reversible, potent, competitive direct thrombin inhibitor (Ki=4.5 nM). Dabigatran (BIBR 953) also inhibits thrombin-induced platelet aggregation (IC50=10 nM)[2][3].
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- HY-101981S
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Uridine 5'-monophosphate-15N2 is the 15N labeled Uridine 5'-monophosphate[1]. Uridine 5'-monophosphate (5'- Uridylic acid), a monophosphate form of UTP, can be acquired either from a de novo pathway or degradation products of nucleotides and nucleic acids in vivo and is a major nucleotide analogue in mammalian milk[2].
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- HY-103395S1
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Methylmalonic acid- 13C4 is the 13C labeled Methylmalonic acid[1]. Methylmalonic acid (Methylmalonate) is an indicator of Vitamin B-12 deficiency in cancer[2].
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- HY-108872S1
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Water- 17O is the 17O labeled Water .
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- HY-109591S
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Oleoyl coenzyme A- 13C18 (lithium) is the 13C labeled Oleoyl Coenzyme A lithium[1]. Oleoyl coenzyme A (Oleoyl-CoA) is a thioester of oleic acid and coenzyme A. Oleoyl coenzyme A has a role as an Escherichia coli metabolite and a mouse metabolite[2][3].
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- HY-113008S1
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Urocanic acid- 13C3 is the 13C labeled Urocanic acid[1]. Urocanic acid, produced in the upper layers of mammalian skin, is a major absorber of ultraviolet radiation (UVR)[2].
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- HY-113038AS
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α-Hydroxyglutaric acid- 13C5 (sodium) is the 13C labeled α-Hydroxyglutaric acid sodium[1]. α-Hydroxyglutaric acid (2-Hydroxyglutarate) sodium is an α-hydroxy acid form of glutaric acid. α-Hydroxyglutaric acid sodium is a competitive inhibitor of multiple α-ketoglutarate-dependent dioxygenases, including histone demethylases and the TET family of 5-methlycytosine (5mC) hydroxylases[2].
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- HY-113225S1
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Guanosine triphosphate- 13C10, 15N5 (tetraammonium) is the 13C and 15N labeled Guanosine triphosphate tetraammonium[1]. Guanosine triphosphate is a native nucleotide. The derivatives of GTP may be used as specific inhibitors against COVID-19[2].
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- HY-113248S1
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3-Nitro-L-tyrosine- 13C6 is the 13C labeled 3-Nitro-L-tyrosine[1]. 3-Nitro-L-tyrosine is a biomarker of nitrogen free radical species modified proteins in systemic autoimmunogenic conditions[2].
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- HY-12008S1
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Erlotinib- 13C6 (hydrochloride) is the 13C labeled Erlotinib Hydrochloride[1]. Erlotinib Hydrochloride (CP-358774 Hydrochloride) inhibits purified EGFR kinase with an IC50 of 2 nM[2]. Erlotinib-13C6 (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-122062S
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Fenoxycarb- 13C6 is the 13C labeled Fenoxycarb[1].
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- HY-128738S
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Thymidine-5'-monophosphate- 13C10, 15N2 (disodium) is the 13C and 15N labeled Thymidine-5'-monophosphate disodium salt[1]. Thymidine-5'-monophosphate disodium salt is an endogenous metabolite.
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- HY-128793S
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trans-Stilbene- 13C2 is the 13C labeled trans-Stilbene[1]. trans-Stilbene ((E)-Stilbene) is used in the manufacturing of dye lasers, optical brighteners, non-steroidal synthetic estrogens[2].
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- HY-129974S
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3,3'-Diiodo-L-thyronine- 13C6 is the 13C labeled 3,3'-Diiodo-L-thyronine[1]. 3,3'-Diiodo-L-thyronine (3,3'-T2) is an endogenous metabolite of thyroid hormone. 3,3'-Diiodo-L-thyronine significantly enhances COX activity[2][3].
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- HY-134423S
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Stearoyl coenzyme A- 13C18 (lithium) is the 13C labeled Stearoyl coenzyme A lithium[1]. Stearoyl coenzyme A (Stearoyl-CoA) lithium is an active compound that can be used as a substrate for the determination of stearoyl-Coenzyme desaturase in microsomes[2].
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- HY-13613S
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Dutasteride- 13C6 is the 13C labeled Dutasteride[1]. Dutasteride (GG745) is a potent inhibitor of both 5α-reductase isozymes. Dutasteride may possess off-target effects on the androgen receptor (AR) due to its structural similarity to DHT[2].
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- HY-13623CS
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(1R,3S,4R)-ent-Entecavir- 13C2, 15N is the 13C and 15N labeled (1R,3S,4R)-ent-Entecavir[1].
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- HY-13690S1
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Mitotane- 13C6 is the 13C labeled Mitotane[1]. Mitotane (2,4′-DDD), an isomer of DDD and derivative of dichlorodiphenyltrichloroethane (DDT), is an antineoplastic agent, can be used to research adrenocortical carcinoma. Mitotane exert its adrenocorticolytic effect at least in part through lipotoxicity induced by intracellular free cholesterol (FC) accumulation. Mitotane can have direct pituitary effects on corticotroph cells. Mitotane can induce CYP3A4 gene expression via steroid and xenobiotic receptor (SXR) activation, and has agent-agent interactions[2][3][4][5].
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-
- HY-139427S
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3-Methylglutaconic acid- 13C3 is the 13C labeled 3-Methylglutaconic acid[1].
|
-
- HY-143843S
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Isosorbide-2-mononitrate- 13C6 is the 13C labeled Isosorbide-2-mononitrate[1].
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-
- HY-14608S10
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L-Glutamic acid- 13C2 is the 13C labeled L-Glutamic acid[1]. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals[2].
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- HY-14781S2
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Levomefolic acid- 13C5 is the 13C labeled Levomefolic acid[1]. Levomefolic acid (L-5-MTHF) is an orally active, brain-penetrant natural active form of folic acid and is one of the most widely used folic acid food supplements[2][3].
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- HY-15027S2
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5-Aminosalicylic acid- 13C6 is the 13C labeled 5-Aminosalicylic Acid[1]. 5-Aminosalicylic acid (Mesalamine) acts as a specific PPARγ agonist and also inhibits p21-activated kinase 1 (PAK1) and NF-κB[2][3][4].
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- HY-150525S
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Acetyl-1,2 Coenzyme A- 13C2(Lithium) is the 13C labeled Acetyl-1,2 Coenzyme A Lithium[1].
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- HY-150532S
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(Rac)-Vitamin B5,Calcium Salt Hydrate- 13C3, 15N is the 13C and 15N labeled (Rac)-Vitamin B5,Calcium Salt Hydrate .
|
-
- HY-150631S
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Glutathione-glycine- 13C2, 15N (trifluoroacetate) is the 13C and 15N labeled Glutathione-glycine trifluoroacetate[1].
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-
- HY-150635S
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Uridine-5'-monophosphate- 15N2 (sodium) is the deuterium and 15N labeled Uridine-5'-monophosphate sodium[1].
|
-
- HY-150642S
-
1 Publications Verification
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Guanosine-5 '- monophosphate- 15N5 (sodium) is the 15N labeled Guanosine-5 '- monophosphate sodium[1].
|
-
- HY-150656S
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Adenosine-5′-monophosphate- 15N5 (sodium) is the 15N labeled Adenosine-5′-monophosphate sodium[1].
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-
- HY-150658S
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DMT-2′O-TBDMS-rA(ac)-1- 15N phosphoramidite is the 15N labeled DMT-2′O-TBDMS-rA(ac) phosphoramidite[1].
|
-
- HY-150660S
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25-Hydroxyvitamin D2-(20,21,22,26,27- 13C5) solution is the 13C labeled 25-Hydroxyvitamin D2[1].
|
-
- HY-150661S
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3-Epi-25-hydroxyvitamin D3- 13C5 is the 13C labeled 3-Epi-25-hydroxyvitamin D3[1].
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-
- HY-150663S
-
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1α,25-Dihydroxyvitamin D3-(23,24,25,26,27- 13C5) solution is the 13C labeled 1α,25-Dihydroxyvitamin D3[1].
|
-
- HY-150678S
-
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Adenosine:H20- 13C is the 13C labeled Adenosine:H20[1].
|
-
- HY-150679S
-
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Remdesivir- 13C6 is the 13C labeled Remdesivir[1].
|
-
- HY-150703S
-
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DL-4-Methoxyestradiol- 13C6 is the 13C labeled DL-4-Methoxyestradiol[1].
|
-
- HY-150706S
-
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D-fructose-6-phosphate- 13C6 is the 13C labeled D-fructose-6-phosphate[1].
|
-
- HY-150707S
-
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DL-A-phosphatidylcholine, dipalmitoyl- 13C40 is the 13C labeled DL-A-phosphatidylcholine, dipalmitoyl[1].
|
-
- HY-150708S
-
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Ethyl 2-hydroxy-2-methyl-3-oxobutanoate- 13C is the 13C labeled Ethyl 2-hydroxy-2-methyl-3-oxobutanoate[1].
|
-
- HY-150709S
-
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Adenosine 5'-triphosphate- 13C10, 15N5 (ammonium) is the 13C and 15N labeled Adenosine 5'-triphosphate ammonium[1].
|
-
- HY-150710S
-
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Cytidine 5'-triphosphate- 13C9, 15N3 (ammonium) is the 13C and 15N labeled Cytidine 5'-triphosphate ammonium[1].
|
-
- HY-150711S
-
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|
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Guanosine- 13C10, 15N5 (ammonium) is the 13C and 15N labeled Guanosine ammonium[1].
|
-
- HY-150712S
-
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Uridine triphosphate- 13C9, 15N5 dilithium is the 13C and 15N labeled Uridine triphosphate dilithium .
|
-
- HY-150792S
-
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|
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Inosine- 15N4 is the 15N labeled Inosine[1].
|
-
- HY-150796S
-
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Guanosine 5'-triphosphate, ammonium salt- 15N5 is the 15N labeled Guanosine 5'-triphosphate, ammonium salt[1].
|
-
- HY-150798S
-
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|
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Uridine 5'-triphosphate (ammonium salt)- 15N2 is the 15N labeled Uridine 5'-triphosphate ammonium salt[1].
|
-
- HY-150843S
-
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Adenosine 5'-triphosphate- 15N5 (ammonium) is the 15N labeled Adenosine 5'-triphosphate ammonium[1].
|
-
- HY-150915S
-
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|
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Uracil 4,5- 13C2 is the 13C labeled Uracil[1].
|
-
- HY-150918S
-
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3-(3-Methyl-1H-Prazol-5-yl)Propanoic Acid (MPP) Methyl,pyrazol yl- 13C5 is the 13C labeled 3-(3-Methyl-1H-Prazol-5-yl)Propanoic Acid (MPP) Methyl,pyrazol yl[1].
|
-
- HY-150930S
-
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|
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Cytidine 5'-triphosphate- 15N3 (ammonium) is the 15N labeled Cytidine 5'-triphosphate ammonium[1].
|
-
- HY-150962S
-
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|
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5-Hydroxycytosine- 13C, 15N2 is the 13C and 15N labeled 5-Hydroxycytosine[1].
|
-
- HY-150980S
-
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|
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1,2-O-Isopropylidene-β-L-idofuranuronic-6- 13C acid γ-lactone is the 13C labeled 1,2-O-Isopropylidene-β-L-idofuranuronic acid γ-lactone[1].
|
-
- HY-150981S
-
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|
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1,2-O-Isopropylidene-a-D-glucofuranuronic-6- 13C acid, γ-lactone is the 13C labeled 1,2-O-Isopropylidene-β-L-idofuranuronic acid, γ-lactone[1].
|
-
- HY-151097S
-
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(±)-Benzfendizone- 13C is the 13C labeled (±)-Benzfendizone[1].
|
-
- HY-15550S1
-
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4'-Hydroxy diclofenac- 13C6 is the 13C labeled 4'-Hydroxy diclofenac[1]. 4'-Hydroxy diclofenac is an orally active metabolite of Diclofenac (HY-15036) by cytochrome P450 2C9 (CYP2C9). 4'-Hydroxy diclofenac has anti-inflammatory and analgesic properties[2][3].
|
-
- HY-16561S2
-
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|
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Resveratrol-(4-Hydroxyphenyl)- 13CN6 is the 13C labeled Resveratrol-(4-Hydroxyphenyl)[1].
|
-
- HY-17416AS
-
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Guanfacine- 13C, 15N3 is the 13C and 15N labeled Guanfacine[1]. Guanfacine is an orally active noradrenergic α2A agonist and has high selective for the α2A receptor subtype. Guanfacine has effects in producing hypotension and sedation. Guanfacine can be used for the research of a variety of prefrontal cortex (PFC) cognitive disorders, including tourette's syndrome and attention deficit hyperactivity disorder (ADHD)[2][3][4].
|
-
- HY-18341S2
-
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L-Thyroxine- 13C6 is the 13C labeled L-Thyroxine[1]. L-Thyroxine (Levothyroxine;T4) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4)[2].
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- HY-18569S4
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3-Indoleacetic acid- 13C6 is the 13C labeled 3-Indoleacetic acid[1]. 3-Indoleacetic acid (Indole-3-acetic acid) is the most common natural plant growth hormone of the auxin class. It can be added to cell culture medium to induce plant cell elongation and division .
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- HY-19528S2
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SAH- 13C10 is the 13C labeled SAH[1]. SAH (S-Adenosylhomocysteine) is an amino acid derivative and a modulartor in several metabolic pathways. It is an intermediate in the synthesis of cysteine and adenosine[2]. SAH is an inhibitor for METTL3-METTL14 heterodimer complex (METTL3-14) with an IC50 of 0.9 μM[3].
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- HY-19821S1
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Fmoc-Ile-OH- 13C6, 15N is the 13C and 15N labeled Fmoc-Ile-OH[1]. Fmoc-Ile-OH is an isoleucine derivative[2].
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- HY-21268S
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Methyl linolenate- 13C18 is the 13C labeled Methyl linolenate[1]. Methyl linolenate is a polyunsaturated fattly acid (PUFA). It is used in studies on the mechanisms and prevention of oxidation/peroxidation of unsaturated fatty acids[2][3]. The IC50 is 60 uM[4].
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- HY-22306S
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β-D-Glucose pentaacetate- 13C6 is the 13C labeled β-D-Glucose pentaacetate[1]. β-D-Glucose Pentaacetate (Penta-O-acetyl-β-D-glucopyranose) is used in biochemical reaction.
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- HY-41494S1
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o-Toluic acid-13C is the 13C labeled o-Toluic acid[1]. o-Toluic acid (2-Methylbenzoic acid) is a benzoic acid substituted by a methyl group at position 2. O-Toluic acid plays a role as a xenobiotic metabolite.
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- HY-59243S
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4,7-Dichloroquinoline- 15N is the 15N labeled 4,7-Dichloroquinoline[1].
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- HY-66005S4
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Acetaminophen- 13C2, 15N is the 13C and 15N labeled Acetaminophen[1]. Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM;is a widely used antipyretic and analgesic agent[2][3][4]. Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor[5].
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- HY-79131S5
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Fmoc-Phe-OH- 13C is the 13C labeled Fmoc-Phe-OH[1]. Fmoc-Phe-OH is a phenylalanine derivative[2].
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- HY-79369S1
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Succinic anhydride- 13C2 is the 13C labeled Succinic anhydride[1]. Succinic anhydride is a cyclic anhydride and a nonclaevable ADC linker extracted from patent WO2009064913A1. Succinic anhydride can react with compound 4 of the patent to link the proagent to an amine or hydroxy 1 group of a targeting polypeptide[2].
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- HY-90006S1
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5-Fluorouracil- 13C, 15N2 is the 13C and 15N labeled 5-Fluorouracil[1]. 5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer[2][3]. 5-Fluorouracil also inhibits HIV[4].
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- HY-90006S3
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5-Fluorouracil- 13C4, 15N2 is the 13C and 15N labeled 5-Fluorouracil[1]. 5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer[2][3]. 5-Fluorouracil also inhibits HIV[4].
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- HY-A0061S
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Trifluridine- 13C, 15N2 is the 13C and 15N labeled Trifluridine[1]. Trifluridine (Trifluorothymidine;5-Trifluorothymidine;TFT) is an irreversible thymidylate synthase inhibitor, and thereby suppresses DNA synthesis. Trifluridine is an antiviral agent for herpes simplex virus (HSV) infection. Trifluorothymidine also has anti-orthopoxvirus activity[2].
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- HY-A0070AS1
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Liothyronine- 13C9, 15N is the 13C and 15N labeled Liothyronine[1]. Liothyronine is an active form of thyroid hormone. Liothyronine is a potent thyroid hormone receptors TRα and TRβ agonist with Kis of 2.33 nM for hTRα and hTRβ, respectively[2][3][4].
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- HY-B0003AS
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(2S)-Gemcitabine- 13C, 15N2 (hydrochloride) is the 13C and 15N labeled (2S)-Gemcitabine hydrochloride[1].
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- HY-B0003S
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Gemcitabine- 13C, 15N2 (hydrochloride) is the 13C and 15N labeled Gemcitabine hydrochloride[1]. Gemcitabine Hydrochloride (LY 188011 Hydrochloride) is a pyrimidine nucleoside analog antimetabolite and an antineoplastic agent. Gemcitabine Hydrochloride inhibits DNA synthesis and repair, resulting in autophagyand apoptosis[2][3].
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- HY-B0143S4
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Niacin- 15N, 13C3 is the 13C and 15N labeled Niacin[1]. Niacin (Vitamin B3) is an orally active water-soluble B3 vitamin that is an essential nutrient for humans. Niacin (Vitamin B3) plays a key role in energy metabolism, cell signaling cascades regulating gene expression and apoptosis. Niacin (Vitamin B3) is also used in the study of cardiovascular diseases[2][3].
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- HY-B0152S1
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Adenine- 13C is the 13C labeled Adenine[1]. Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis[2][3][4].
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- HY-B0158S5
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Cytidine- 13C9, 15N3 is the 13C and 15N labeled Cytidine[1]. Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catecholamine synthesis, and mitochondrial function[2][3][4].
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- HY-B0158S6
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Cytidine- 15N3 is the 15N labeled Cytidine[1]. Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catecholamine synthesis, and mitochondrial function[2][3][4].
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- HY-B0211S
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Riluzole- 13C, 15N2 is the 13C and 15N labeled Riluzole[1]. Riluzole is an anticonvulsant agent and belongs to the family of use-dependent Na+ channel blocker which can also inhibit GABA uptake with an IC50 of 43 μM[2][3].
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- HY-B0224S
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Chlorothiazide- 13C, 15N2 is the 13C and 15N labeled Chlorothiazide[1]. Chlorothiazide is an orally active diuretic and anti-hypertensive agent[2].
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- HY-B0228S1
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Adenosine- 13C5 is the 13C labeled Adenosine[1]. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation[2][3].
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- HY-B0252S2
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Hydrochlorothiazide- 13C6 is the 13C labeled Hydrochlorothiazide[1]. Hydrochlorothiazide (HCTZ), an orally active diuretic agent of the thiazide class, inhibits transforming TGF-β/Smad signaling pathway. Hydrochlorothiazide has direct vascular relaxant effects via opening of the calcium-activated potassium (KCA) channel. Hydrochlorothiazide improves cardiac function, reduces fibrosis and has antihypertensive effect[2][3][4].
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- HY-B0285AS
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Amiloride- 15N3 (hydrochloride) is the 15N labeled Amiloride hydrochloride[1]. Amiloride hydrochloride (MK-870 hydrochloride) is an inhibitor of both epithelial sodium channel (ENaC[2]) and urokinase-type plasminogen activator receptor (uTPA[3]). Amiloride hydrochloride is a blocker of polycystin-2 (PC2;TRPP2[4]) channel.
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- HY-B0345AS
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ATP- 18O4 (disodium salt) is the 18O labeled ATP disodium salt[1]. ATP disodium salt (Adenosine 5'-triphosphate disodium salt) is a central component of energy storage and metabolism in vivo, provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP disodium salt is an important endogenous signaling molecule in immunity and inflammation[2][3].
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- HY-B0347S1
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Lacidipine- 13C8 is the deuterium labeled Lacidipine[1]. Lacidipine is an orally active and highly selective L-type calcium channel blocker that acts on smooth muscle calcium channels, primarily dilates peripheral arteries, reduces peripheral resistance, and has long-lasting anti-hypertensive activity. Lacidipine protects HKCs from apoptosis induced by ATP depletion and recovery by modulating the caspase-3 pathway. Lacidipine can be used in studies of hypertension, atherosclerosis and acute kidney injury (AKI)[2][3].
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- HY-B0400S16
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D-Sorbitol- 13C6 is the 13C labeled D-Sorbitol[1]. D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and dietary supplement[2].
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- HY-B0445S1
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NAD+- 13C5-1 is the 13C labeled NAD+[1]. NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage.
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- HY-B0448S1
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Phenytoin- 15N2, 13C is the 13C and 15N labeled Phenytoin[1]. Phenytoin (5,5-Diphenylhydantoin) is a potent Voltage-gated Na+ channels (VGSCs) blocker. Phenytoin has antiepileptic activity and reduces breast tumour growth and metastasis in mice[2][3].
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- HY-B0476S1
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Phenacetin- 13C is the 13C labeled Phenacetin[1]. Phenacetin (Acetophenetidin) is a non-opioid analgesic/antipyretic agent. Phenacetin is a selective COX-3 inhibitor. Phenacetin is used as probe of cytochrome P450 enzymes CYP1A2 in human liver microsomes and in rats[2][3][4].
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- HY-B0495S3
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Lamotrigine-13C2,15N is the 13C and 15N labeled Lamotrigine[1]. Lamotrigine (BW430C) is a potent and orally active anticonvulsant or antiepileptic agent. Lamotrigine selectively blocks voltage-gated Na+ channels, stabilizing presynaptic neuronal membranes and inhibiting glutamate release. Lamotrigine can be used for the research of epilepsy, focal seizure, et al[2][3].
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- HY-B0497BS
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Niclosamide- 13C6 (monohydrate) is the 13C labeled Niclosamide monohydrate[1]. Niclosamide (BAY2353) monohydrate is an orally active antihelminthic agent used in parasitic infection research[2]. Niclosamide monohydrate is a STAT3 inhibitor with an IC50 of 0.25 μM in HeLa cells[5]. Niclosamide monohydrate has biological activities against cancer, and inhibits DNA replication in Vero E6 cells[3][4][6].
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- HY-B0617S1
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S-Adenosyl-L-methionine- 13C is the 13C labeled S-Adenosyl-L-methionine[1]. S-Adenosyl-L-methionine (S-Adenosyl methionine) is produced endogenously from methionine and ATP by action of the enzyme methionine adenosyltransferase and is an important orally active methyl group donor. S-Adenosyl-L-methionine is a dietary supplement with potent antidepressant effects, and has the potential for liver disease and osteoarthritis research[2][3][4].
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- HY-B0892S3
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Benzyl alcohol- 13C6 is the 13C labeled Benzyl alcohol[1].
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- HY-B1075AS
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(Rac)-Fosfomycin (benzylamine)- 13C3 is the 13C labeled Fosfomycin[1]. Fosfomycin (MK-0955) is a broad-spectrum antibiotic. Fosfomycin can cross blood-brain barrier penetrating, and irreversibly inhibits an early stage in cell wall synthesis. Fosfomycin shows anti-bacteria activity for a range of bacteria, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria[2][3].
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- HY-B1337S5
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Choline- 13C2 (chloride) is the 13C labeled Choline chloride[1]. Choline chloride is an essential nutrient that activates alpha7 nicotinic receptors and has analgesic and anti-inflammatory activity. Glycerophosphoinositol choline can affect diseases such as liver disease, atherosclerosis and neurological disorders[2][3].
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- HY-B1409S
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Isosorbide dinitrate- 13C6 is the 13C labeled Isosorbide dinitrate[1]. Isosorbide dinitrate (ISDN) is an NO donor that prevents LV remodeling and degradation of cardiac function following myocardial infarction (MI)[2].
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- HY-B1431S1
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Butylparaben- 13C6 is the 13C labeled Butylparaben[1]. Butylparaben is an organic compound, has proven to be a highly successful antimicrobial preservative in cosmetics, also used in medication suspensions, and as a flavoring additive in food.
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- HY-B1449S
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Uridine- 15N2 is the 15N labeled Uridine[1].
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- HY-B1449S7
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Uridine 13C-4 is the 13C labeled Uridine[1].
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- HY-B1459AS
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Dicloxacillin- 13C4 is the 13C labeled Dicloxacillin[1]. Dicloxacillin is a β-lactam antibiotic of the penicillin family. Dicloxacillin against Gram-positive bacteria. Dicloxacillin is active against β-lactamase-producing organisms such as Staphylococcus aureus[2].
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- HY-B1659S4
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Glycerol- 13C2 is the 13C labeled Glycerol[1]. Glycerol is used in sample preparation and gel formation for polyacrylamide gel electrophoresis[2][3][4].
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- HY-B1659S5
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Glycerol- 13C3 is the 13C labeled Glycerol[1]. Glycerol is used in sample preparation and gel formation for polyacrylamide gel electrophoresis[2][3][4].
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- HY-B1773AS
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Propanoic- 13C (sodium) is the 13C labeled Sodium Propionate[1].
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- HY-B1773AS3
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Propanoic- 13C3 (sodium) is the 13C labeled Sodium Propionate[1].
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- HY-B1779S5
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Sucrose-13C6 is the 13C labeled Sucrose[1]. Sucrose (D-(+)-Saccharose) is a disaccharide which is composed of two monosaccharides, glucose and fructose. Sucrose can be applied in some animal models, including metabolic disease, obesity, diet on preference, and diabetes, et al[2].
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- HY-B2130S1
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Uric acid- 15N2 is the 15N labeled Uric acid . Uric acid, scavenger of oxygen radical, is a very important antioxidant that help maintains the stability of blood pressure and antioxidant stress. Uric acid can remove reactive oxygen species (ROS) such as singlet oxygen and peroxynitrite, inhibiting lipid peroxidation .
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- HY-B2176S
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ATP- 13C10, 15N5 is the 13C and 15N labeled ATP[1]. ATP (Adenosine 5'-triphosphate) is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation[2][3].
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- HY-B2227BS2
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Lactate- 13C (sodium) is the 13C labeled Lactate sodium[1]. Lactate (Lactic acid) sodium is the product of glycogenolysis and glycolysis. Lactate (Lactic acid) sodium functions in a variety of biochemical processes[2].
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- HY-B2227BS3
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Lactate- 13C-1 (sodium) is the 13C labeled Lactate (sodium)[1]. Lactate (Lactic acid) sodium is the product of glycogenolysis and glycolysis. Lactate (Lactic acid) sodium functions in a variety of biochemical processes[2].
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- HY-D0184S2
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2'-Deoxycytidine- 15N3 is the 15N labeled 2'-Deoxycytidine[1]. 2'-Deoxycytidine, a deoxyribonucleoside, could inhibit biological effects of Bromodeoxyuridine (Brdu)[2].
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- HY-D0185S4
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2'-Deoxyguanosine- 13C10, 15N5 (monohydrate) is the 13C and 15N labeled 2'-Deoxyguanosine monohydrate[1]. 2'-Deoxyguanosine monohydrate is an endogenous metabolite.
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- HY-D0186S7
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2'-Deoxyuridine- 13C, 15N2 is the 13C and 15N labeled 2'-Deoxyuridine[1]. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxudine[2].
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- HY-D0199S
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Adenosine- 15N5 5′-diphosphate (disodium salt) is the 15N labeled Adenosine 5'-diphosphate disodium salt[1].
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- HY-I0626S1
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Cytosine- 13C, 15N2 is the 13C and 15N labeled Cytosine[1]. Cytosine is one of the four main bases found in DNA and RNA. Cytosine modifications exhibit circadian oscillations that are involved in epigenetic diversity and aging[2][3].
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- HY-I0960S1
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Uracil- 13C4 is the 13C labeled Uracil[1]. Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA[2].
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- HY-I0960S2
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Uracil- 13C is the 13C labeled Uracil[1]. Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA[2].
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- HY-I0960S3
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Uracil- 13C4, 15N2 is the 13C and 15N labeled Uracil[1]. Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA[2].
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- HY-I0960S5
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Uracil- 15N2 is the 15N labeled Uracil[1]. Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA[2].
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- HY-N0090S3
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Guanosine- 13C10, 15N5 (hydrate) is the 13C and 15N labeled Guanosine Hydrate[1].
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- HY-N0091S7
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1 Publications Verification
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Hypoxanthine- 15N4 is the 15N labeled Hypoxanthine[1]. Hypoxanthine, a purine derivative, is a potential free radical generator and could be used as an indicator of hypoxia[2].
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- HY-N0097S3
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Guanosine- 15N5 is the 15N labeled Guanosine[1]. Guanosine (DL-Guanosine) is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. Guanosine possesses anti-HSV activity[2].
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- HY-N0098S2
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Vanillin- 13C6 is the 13C labeled Vanillin[1]. Vanillin (p-Vanillin) is a single molecule extracted from vanilla beans and also a popular odor used widely in perfume, food and medicine[2][3].
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- HY-N0098S3
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Vanillin- 13C is the 13C labeled Vanillin[1]. Vanillin (p-Vanillin) is a single molecule extracted from vanilla beans and also a popular odor used widely in perfume, food and medicine[2][3].
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- HY-N0157S1
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Orotic acid- 13C, 15N2 (monohydrate) is the 13C and 15N labeled Orotic acid[1]. Orotic acid (6-Carboxyuracil), a precursor in biosynthesis of pyrimidine nucleotides and RNA, is released from the mitochondrial dihydroorotate dehydrogenase (DHODH) for conversion to UMP by the cytoplasmic UMP synthase enzyme. Orotic acid is a marker for measurement in routine newborn screening for urea cycle disorders. Orotic acid can induce hepatic steatosis and hepatomegaly in rats[2][3][4].
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- HY-N0304S1
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L-DOPA- 13C6 is the 13C-labled L-DOPA . L-DOPA (Levodopa) is an orally active metabolic precursor of neurotransmitters dopamine. L-DOPA can cross the blood-brain barrier and is converted into dopamine in the brain. L-DOPA has anti-allodynic effects and the potential for Parkinson's disease .
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- HY-N0304S2
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1 Publications Verification
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L-DOPA- 13C is the 13C labeled L-DOPA[1]. L-DOPA (Levodopa) is an orally active metabolic precursor of neurotransmitters dopamine. L-DOPA can cross the blood-brain barrier and is converted into dopamine in the brain. L-DOPA has anti-allodynic effects and the potential for Parkinson's disease[2][3][4].
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- HY-N0305S2
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5-Aminolevulinic acid- 13C (hydrochloride) is the 13C labeled 5-Aminolevulinic acid hydrochloride[1]. 5-Aminolevulinic acid hydrochloride (5-ALA hydrochloride) is an intermediate in heme biosynthesis in the body and the universal precursor of tetrapyrroles[2][3].
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- HY-N0305S3
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5-Aminolevulinic acid- 13C-1 (5-ALA- 13C-1) hydrochloride is the 13C labeled 5-Aminolevulinic acid hydrochloride . 5-Aminolevulinic acid hydrochloride (5-ALA hydrochloride) is an intermediate in heme biosynthesis in the body and the universal precursor of tetrapyrroles .
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- HY-N0378S2
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D-Mannitol- 13C6 is the 13C labeled D-Mannitol[1]. D-Mannitol is an osmotic diuretic agent and a weak renal vasodilator[2][3][4].
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- HY-N0379S22
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D-Mannose- 13C6 is a carbohydrate, which plays an important role in human metabolism, especially in the glycosylationof specific proteins[2].
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- HY-N0394S4
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L-Cystine-3,3'- 13C2 is the 13C labeled L-Cystine[1]. L-Cystine is an amino acid and intracellular thiol, which plays a critical role in the regulation of cellular processes[2].
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- HY-N0420S2
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Succinic acid- 13C4 is the 13C labeled Succinic acid[1]. Succinic acid is a potent and orally active anxiolytic agent. Succinic acid is an intermediate product of the tricarboxylic acid cycle. Succinic acid can be used as a precursor of many industrially important chemicals in food, chemical and pharmaceutical industries[2][3].
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- HY-N0420S3
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Butanedioic acid- 13C2 is the 13C labeled Succinic acid[1]. Succinic acid is a potent and orally active anxiolytic agent. Succinic acid is an intermediate product of the tricarboxylic acid cycle. Succinic acid can be used as a precursor of many industrially important chemicals in food, chemical and pharmaceutical industries[2][3].
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- HY-N0420S4
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Succinic acid- 13C2 is the 13C labeled Succinic acid[1]. Succinic acid is a potent and orally active anxiolytic agent. Succinic acid is an intermediate product of the tricarboxylic acid cycle. Succinic acid can be used as a precursor of many industrially important chemicals in food, chemical and pharmaceutical industries[2][3].
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- HY-N0470S8
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L-Lysine- 13C6 hydrochloride is the 13C labeled L-Lysine hydrochloride[1]. L-lysine hydrochloride is an essential amino acid for humans with various benefits including treating herpes, increasing calcium absorption, reducing diabetes-related illnesses and improving gut health[2][3][4].
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- HY-N0473S16
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L-Tyrosine- 13C, 15N is the 13C and 15N labeled L-Tyrosine[1]. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex[2].
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- HY-N0543S
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Allantoin- 13C2, 15N4 is the 13C and 15N labeled Allantoin[1]. Allantoin is a skin conditioning agent that promotes healthy skin, stimulates new and healthy tissue growth[2].
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- HY-N0623S10
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L-Phenylalanine,Indole- 15N is the 15N labeled L-Tryptophan[1]. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[2].
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- HY-N0658S6
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L-Threonine- 13C4 is the 13C labeled L-Threonine[1]. L-Threonine is a natural amino acid, can be produced by microbial fermentation, and is used in food, medicine, or feed[2].
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- HY-N0666S10
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L-Aspartic acid- 13C-1 is the deuterium labeled L-Aspartic acid[1]. L-Aspartic acid is is an amino acid, shown to be a suitable proagent for colon-specific agent deliverly[2][3].
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- HY-N1150S8
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Thymidine- 13C10, 15N2 is the 13C and 15N labeled Thymidine[1]. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication[2][3][4].
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-
- HY-N1150S9
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Thymidine- 15N2 is the 15N labeled Thymidine[1]. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication[2][3][4].
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- HY-N1380S2
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Guaiacol- 13C6 is the 13C labeled Guaiacol[1]. Guaiacol, a phenolic compound, inhibits LPS-stimulated COX-2 expression and NF-κB activation[1]. Anti-inflammatory activity[2].
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- HY-N1428S3
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Citric acid- 13C3 is the 13C labeled Citric acid[1]. Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid causes renal toxicity in mice[2][3][4].
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- HY-N2362S5
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DL-Alanine- 15N is the 15N labeled DL-Alanine[1]. DL-alanine, an amino acid, is the racemic compound of L- and D-alanine. DL-alanine is employed both as a reducing and a capping agent, used with silver nitrate aqueous solutions for the production of nanoparticles. DL-alanine can be used for the research of transition metals chelation, such as Cu(II), Zn(II), Cd(11). DL-alanine, a sweetener, is classed together with glycine, and sodium saccharin. DL-alanine plays a key role in the glucose-alanine cycle between tissues and liver[2][3][4][5][6][7].
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- HY-N7032S1
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Uridine 5′-diphosphoglucose- 13C6 (disodium) is the 13C labeled Uridine 5′-diphosphoglucose disodium salt[1]. Uridine 5′-diphosphoglucose disodium salt (UDP-D-Glucose disodium salt) is the precursor of glucose-containing oligosaccharides, polysaccharides, glycoproteins, and glycolipids in animal tissues and in some microorganisms. Uridine-5′-diphosphoglucose is an agonist of the P2Y14 receptor, a neuroimmune system GPCR[2].
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-
- HY-W001132S1
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Indole- 13C is the 13C labeled Indole[1]. Indole is an endogenous metabolite.
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-
- HY-W001132S2
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Indole- 13C8, 15N is the 13C and 15N labeled Indole[1]. Indole is an endogenous metabolite.
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-
- HY-W001132S3
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Indole- 15N is the 15N labeled Indole[1]. Indole is an endogenous metabolite.
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-
- HY-W005355S2
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Sodium 2-oxobutanoate- 13C (hydrate) is the 13C labeled Sodium 2-oxobutanoate[1].
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-
- HY-W005355S9
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Sodium 2-oxobutanoate- 13C4 is the 13C labeled Sodium 2-oxobutanoate[1].
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- HY-W006057AS16
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Sodium 3-methyl-2-oxobutanoate- 13C5 is the 13C labeled Sodium 3-methyl-2-oxobutanoate[1]. Sodium 3-methyl-2-oxobutanoate is a precursor of pantothenic acid in Escherichia coli[2][3][4].
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-
- HY-W006057AS17
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3-Methyl-2-oxobutanoic acid- 13C2 is the 13C labeled Sodium 3-methyl-2-oxobutanoate[1]. Sodium 3-methyl-2-oxobutanoate is a precursor of pantothenic acid in Escherichia coli[2][3][4].
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- HY-W007941S1
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Fmoc-Ser(tBu)-OH- 15N is the 15N labeled Fmoc-Ser(tBu)-OH[1]. Fmoc-Ser(tBu)-OH is a serine derivative[2].
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- HY-W008807S
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Phosphoenolpyruvic acid (potassium)- 13C2 is the 13C labeled Phosphoenolpyruvic acid (potassium)[1]. Potassium 1-carboxyvinyl hydrogenphosphate is an endogenous metabolite.
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- HY-W008848S
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DMT-dG(ib) Phosphoramidite- 13C10, 15N5 is the 13C and 15N labeled DMT-dG(ib) Phosphoramidite[1]. DMT-dG(ib) Phosphoramidite is typically used in the synthesis of DNA[2].
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- HY-W008848S1
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DMT-dG(ib) Phosphoramidite- 15N5 is the 15N labeled DMT-dG(ib) Phosphoramidite[1]. DMT-dG(ib) Phosphoramidite is typically used in the synthesis of DNA[2].
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-
- HY-W008849S
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DMT-dC(bz) Phosphoramidite- 13C9, 15N3 is the 13C and 15N labeled DMT-dC(bz) Phosphoramidite[1]. DMT-dC(bz) Phosphoramidite is typically used in the synthesis of DNA[2].
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-
- HY-W009162S
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Cytidine 5′-monophosphate- 15N3 (disodium) is the 15N labeled Cytidine 5'-monophosphate disodium[1]. Cytidine 5'-monophosphate (5'-Cytidylic acid) disodium is a nucleotide which is used as a monomer in RNA. Cytidine 5'-monophosphate disodium consists of the nucleobase cytosine, the pentose sugar ribose, and the phosphate group[2].
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-
- HY-W009216S
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2'-Deoxycytidine-5'-monophosphoric acid- 15N3 is the 15N labeled 2'-Deoxycytidine-5'-monophosphoric acid[1]. 2'-Deoxycytidine-5'-monophosphoric acid is an endogenous metabolite.
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-
- HY-W009296S1
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Tri-p-tolylamine- 15N is the deuterium labeled Tri-p-tolylamine[1].
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-
- HY-W009597S
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1,5-Dichloro-2,4-dinitrobenzene- 13C6 is the 13C labeled 1,5-Dichloro-2,4-dinitrobenzene[1].
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-
- HY-W010184S
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4,6-Dioxoheptanoic acid- 13C5 is the 13C labeled 4,6-Dioxoheptanoic acid[1]. 4,6-Dioxoheptanoic acid is a potent inhibitor of heme biosynthesis[2].
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-
- HY-W010388S
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Creatine- 13C is the 13C labeled Creatine[1]. Creatine, an endogenous amino acid derivative, plays an important role in cellular energy, especially in muscle and brain[2].
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-
- HY-W010407S2
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Cyanuric acid- 13C3, 15N3 is the 13C and 15N labeled Cyanuric acid[1].
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-
- HY-W010450S2
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Thymine- 15N2 is the 15N labeled Thymine[1]. Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a Km of 2.3 μM[2].
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-
- HY-W010450S3
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Thymine- 13C is the 13C labeled Thymine[1]. Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a Km of 2.3 μM[2].
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-
- HY-W010712S1
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Fmoc-His(Trt)-OH- 15N3 is the 15N labeled Fmoc-His(Trt)-OH[1]. Fmoc-His(Trt)-OH has trityl (Trt) group to protect the side-chain of His. Fmoc-His(Trt)-OH has Fmoc group to protect -αNH2. Fmoc-His(Trt)-OH can be used for solid phase synthesis of peptides, providing protection against racemization and by-product formation[2].
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-
- HY-W011012S2
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Adenosine-5'-monophosphate- 15N5 (disodium) is the deuterium labeled Adenosine 5'-monophosphate disodium salt[1].
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-
- HY-W011090S
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((2R,3S,4R,5R)-5-(4-Amino-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate- 13C9, 15N3 (sodium) is the 13C and 15N labeled Sodium ((2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate[1].
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-
- HY-W011540S
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8-Hydroxy-2'-deoxyguanosine- 15N5 is the 15N labeled 8-Hydroxy-2'-deoxyguanosine[1]. 8-Hydroxy-2'-deoxyguanosine is a critical biomarker of oxidative stress and carcinogenesis[2].
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-
- HY-W011683S6
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2'-Deoxyadenosine monohydrate- 13C10, 15N5 (hydrate) is the 13C and 15N labeled 2'-Deoxyadenosine monohydrate[1]. 2'-Deoxyadenosine monohydrate is a deoxyribonucleoside. A building block in the chemical synthesis.
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-
- HY-W011683S7
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2'-Deoxyadenosine monohydrate- 15N5 is the 15N labeled 2'-Deoxyadenosine monohydrate[1]. 2'-Deoxyadenosine monohydrate is a deoxyribonucleoside. A building block in the chemical synthesis.
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-
- HY-W012684S
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Ethane-1,2-diamine dihydrochloride- 13C2 is the 13C labeled Ethane-1,2-diamine dihydrochloride[1].
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-
- HY-W012926S
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Dihydrouracil- 13C4, 15N2 is the 13C and 15N labeled Dihydrouracil[1]. Dihydrouracil (5,6-Dihydrouracil), a metabolite of Uracil, can be used as a marker for identification of dihydropyrimidine dehydrogenase (DPD)-deficient[2][3].
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-
- HY-W013059S
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DMT-dA(bz) Phosphoramidite- 13C10, 15N5 is the 13C and 15N labeled DMT-dA(bz) Phosphoramidite[1]. DMT-dA(bz) Phosphoramidite is typically used in the synthesis of DNA[2].
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-
- HY-W013059S1
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DMT-dA(bz) Phosphoramidite- 15N5 is the 15N labeled DMT-dA(bz) Phosphoramidite[1]. DMT-dA(bz) Phosphoramidite is typically used in the synthesis of DNA[2].
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-
- HY-W013061S10
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Propane-1,2,3-triyl tripalmitate- 13C is the 13C labeled Propane-1,2,3-triyl tripalmitate[1]. Propane-1,2,3-triyl tripalmitate is an endogenous metabolite.
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-
- HY-W013068S
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DMT-dT Phosphoramidite- 13C10, 15N2 is the 13C and 15N labeled DMT-dT Phosphoramidite[1]. DMT-dT Phosphoramidite is typically used in the synthesis of DNA[2].
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- HY-W013068S1
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DMT-dT Phosphoramidite- 15N2 is the 15N labeled DMT-dT Phosphoramidite[1]. DMT-dT Phosphoramidite is typically used in the synthesis of DNA[2].
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- HY-W013159S
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2'-Deoxyguanosine 5'-monophosphate- 13C10, 15N5 (disodium) is the 13C and 15N labeled 2'-Deoxyguanosine 5'-monophosphate disodium[1]. 2'-Deoxyguanosine 5'-monophosphate disodium (5′-dGMP disodium) is a mononucleotide having guanine as the nucleobase. 2'-Deoxyguanosine 5'-monophosphate disodium is a nucleic acid guanosine triphosphate (GTP) derivative[2].
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- HY-W013175S2
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Uridine 5'-monophosphate- 13C9, 15N2 (disodium) is the 13C and 15N labeled Uridine 5'-monophosphate disodium salt[1]. Uridine 5'-monophosphate disodium salt is component used for RNA synthesis[2].
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- HY-W013636S
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2-Ketoglutaric acid- 13C5 is the 13C labeled 2-Ketoglutaric acid[1]. 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC50=15 mM)[2].
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- HY-W014633S1
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4-(Trifluoromethoxy)benzoic acid- 13C is the 13C labeled 4-(Trifluoromethoxy)benzoic acid[1].
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- HY-W015213S
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Adenine monohydrochloride hemihydrate- 15N5 is the 15N labeled Adenine monohydrochloride hemihydrate[1]. Adenine monohydrochloride hemihydrate is an endogenous metabolite.
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- HY-W015410S
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Disodium succinate-13C2 is the 13C labeled Disodium succinate[1]. Disodium succinate is the disodium salt of Succinic acid. Succinic acid is an intermediate product of the tricarboxylic acid cycle, as well as one of fermentation products of anaerobic metabolism[2].
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- HY-W015851S
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3-Hydroxybutanoic acid-13C- 13C (sodium) is the 13C labeled 3-Hydroxybutanoic acid sodium (HY-W010452). 3-Hydroxybutyric acid sodium (β-Hydroxybutyric acid sodium) is a metabolite that is elevated in type I diabetes. 3-Hydroxybutyric acid sodium can modulate the properties of membrane lipids .
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- HY-W015913S3
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Sodium 2-oxopropanoate- 13C is the 13C labeled Sodium 2-oxopropanoate[1]. Sodium 2-oxopropanoate (Sodium pyruvate), a three-carbon metabolite of Glucose, is a compound produced in the glycolytic pathway. Sodium 2-oxopropanoate is a free radical scavenger that can scavenge ROS[2][3].
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- HY-W015913S4
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2-Oxopropanoate- 13C5 (sodium) is the 13C labeled Sodium 2-oxopropanoate[1]. Sodium 2-oxopropanoate (Sodium pyruvate), a three-carbon metabolite of Glucose, is a compound produced in the glycolytic pathway. Sodium 2-oxopropanoate is a free radical scavenger that can scavenge ROS[2][3].
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- HY-W016145S
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L-Glutamic acid- 13C5 (hydrate salt) is the 13C labeled L-Glutamic acid hydrate salt[1].
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- HY-W016433S
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2-Aminofluorene- 13C is the 13C labeled 2-Aminofluorene[1]. 2-Aminofluorene is a synthetic chemical insecticide. 2-Aminofluorene is a genotoxin. 2-Aminofluorene can be used in the research of DNA adduct structure, DNA repair, carcinogenesis, and mutagenesis[2][3][4].
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-
- HY-W016812S
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Orotic acid- 15N2 is the 15N hydrate labeled Orotic acid hydrate . Orotic acid hydrate is an endogenous metabolite.
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-
- HY-W017163S
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7-Methylxanthine-2,4,5,6- 13C4, 1,3- 15N2 (with variable 15N labeling at N9) is the 13C and 15N labeled 7-Methylxanthine[1]. 7-Methylxanthine, a methyl derivative of xanthine, is one of the purine components in urinary calculi[2].
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-
- HY-W017387S1
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Sodium α-ketoisocaproic acid- 13C2 is the 13C labeled Sodium α-ketoisocaproic acid[1].
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-
- HY-W017387S2
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Sodium α-ketoisocaproic acid- 13C5 is the 13C labeled Sodium α-ketoisocaproic acid[1].
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- HY-W017443S4
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L-Asparagine-1,2,3,4- 13C4 (monohydrate) is the 13C labeled L-Asparagine (monohydrate)[1]. L-Asparagine monohydrate ((-)-Asparagine monohydrate) is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue.
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- HY-W017455S1
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2,6-Diethylaniline- 15N is the deuterium labeled 2,6-Diethylaniline[1].
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- HY-W017522S1
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Adipic acid- 13C6 is the 13C labeled Adipic acid[1]. Adipic acid is found to be associated with HMG-CoA lyase deficiency, carnitine-acylcarnitine translocase deficiency, malonyl-Coa decarboxylase deficiency, and medium Chain acyl-CoA dehydrogenase deficiency, which are inborn errors of metabolism[2].
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- HY-W017522S3
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Adipic acid- 13C is the 13C labeled Adipic acid[1]. Adipic acid is found to be associated with HMG-CoA lyase deficiency, carnitine-acylcarnitine translocase deficiency, malonyl-Coa decarboxylase deficiency, and medium Chain acyl-CoA dehydrogenase deficiency, which are inborn errors of metabolism[2].
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-
- HY-W018603S
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Trifluorothymine- 13C, 15N2 is the 13C and 15N labeled Trifluorothymine[1].
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-
- HY-W018772S15
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D-Ribose(mixture of isomers)- 13C5 isomers)- 13C5 is the 13C labeled D-Ribose(mixture of isomers)[1]. D-Ribose(mixture of isomers) is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose(mixture of isomers) is active in protein glycation, induces NF-κB inflammation in a RAGE-dependent manner[1].
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- HY-W021400S
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Sodium 2-Methylpropionate-1- 13C is the 13C labeled Sodium 2-Methylpropionate[1].
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- HY-W021448S1
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Glycocyamine- 15N, 13C2 is the 13C and 15N labeled Glycocyamine[1]. Glycocyamine (Guanidinoacetic acid), a precursor of creatine, is a replacement of dietary arginine and could support overall energy homeostasis of the bird[2].
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- HY-W028026S
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Methacetin-methoxy- 13C is the 13C labeled Methacetin-methoxy[1].
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-
- HY-W035903S
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Ethanolamine- 13C2 hydrochloride is the 13C labeled Ethanolamine hydrochloride[1].
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- HY-W041171S
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3-Chloro-L-tyrosine- 13C6 is the 13C labeled 3-Chloro-L-tyrosine[1]. 3-Chloro-L-tyrosine is a specific marker of myeloperoxidase-catalyzed oxidation, and is markedly elevated in low density lipoprotein isolated from human atherosclerotic intima[2].
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- HY-W050145S2
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Levoglucosan- 13C6 is the 13C labeled Levoglucosan[1]. Levoglucosan (1,6-Anhydro-β-D-glucopyranose) is an anhydrosugar produced through glucan pyrolysis and is widely found in nature[2].
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- HY-W088065S
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Formate- 13C (sodium) is the 13C labeled Sodium formate[1].
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-
- HY-W096993S1
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TPABr (Tetrapropylammonium bromide)- 15N is the 15N labeled TPABr (Tetrapropylammonium bromide) .
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-
- HY-W105272S
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2′-Deoxyadenosine 5′-monophosphate- 13C10, 15N5 (disodium) is the 13C and 15N labeled 2′-Deoxyadenosine 5′-monophosphate disodium[1]. 2′-Deoxyadenosine 5′-monophosphate disodium, a nucleic acid AMP derivative, is a deoxyribonucleotide found in DNA. 2′-Deoxyadenosine 5′-monophosphate disodium can be used to study adenosine-based interactions during DNA synthesis and DNA damage[2].
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-
- HY-W105860S
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Guanidine Hydrobromide- 15N3 is the 15N labeled Guanidine Hydrobromide[1].
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-
- HY-W110705S
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1-Bromopentadecane-1- 13C is the 13C labeled 1-Bromopentadecane[1].
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-
- HY-W243018S
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1,2:5,6-Di-O-isopropylidene-a-D-glucofuranose-1,2,3,4,5,6- 13C6 is the 13C labeled (3aS,5R,6R,6aS)-5-((S)-2,2-Dimethyl-1,3-dioxolan-4-yl)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-6-ol[1].
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-
- HY-W251598S
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Bicarbonate- 13C (sodium) is the 13C labeled Bicarbonate sodium[1].
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-
- HY-W344468S
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Adipate- 13C6 (sodium) is the 13C labeled Sodium adipate[1].
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-
- HY-W392933S
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Thymidine 5'-monophosphate- 15N2 is the 15N labeled Thymidine 5'-monophosphate[1].
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-
- HY-Y0261AS1
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Ammonium sulphate,≥99.0%,AR- 15N2 is the deuterium labeled Ammonium sulphate,≥99.0%,AR[1]. Ammonium sulphate,≥99.0%,AR is an inorganic sulfate salt used for molecular biology[2].
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- HY-Y0262BS
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Oxalic Acid- 13C2 (disodium) is the 13C labeled Oxalic Acid disodium[1].
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- HY-Y0264S2
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4-Hydroxybenzoic acid- 13C is the 13C labeled 4-Hydroxybenzoic acid[1]. 4-Hydroxybenzoic acid, a phenolic derivative of benzoic acid, could inhibit most gram-positive and some gram-negative bacteria, with an IC50 of 160 μg/mL[2].
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- HY-Y0271S2
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Urea- 13C, 15N2 is the 13C and 15N labeled Urea[1]. Urea is a powerful protein denaturant via both direct and indirect mechanisms[1]. A potent emollient and keratolytic agent[2]. Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function[3]. Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry.
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-
- HY-Y0287AS
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Calcium carbonate,99.8%,PT- 13C is the 13C labeled Calcium carbonate,99.95-100.05%,PT[1].
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-
- HY-Y0338S1
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Ethylene glycol- 13C2 is the 13C labeled Ethylene glycol[1].
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-
- HY-Y0442S
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2-Methylbenzaldehyde- 13C is the 13C labeled 2-Methylbenzaldehyde[1]. 2-Methylbenzaldehyde is an endogenous metabolite.
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-
- HY-Y0504S2
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Trimethylammonium chloride- 15N is the 15N labeled Trimethylammonium chloride[1]. Trimethylammonium chloride is an endogenous metabolite.
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-
- HY-Y0546S2
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Benzophenone- 13C is the 13C labeled Benzophenone[1]. Benzophenone is an endogenous metabolite.
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-
- HY-Y0781S1
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Pyruvic acid- 13C is the 13C labeled Pyruvic acid[1]. Pyruvic acid is an intermediate metabolite in the metabolism of carbohydrates, proteins, and fats[2].
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-
- HY-Y0781S3
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Pyruvic acid- 13C-2 (sodium) is the 13C labeled Pyruvic acid[1]. Pyruvic acid is an intermediate metabolite in the metabolism of carbohydrates, proteins, and fats[2].
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-
- HY-Y0827S
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Carbonate- 13C (barium) is the 13C labeled Barium carbonate[1].
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-
- HY-Y0836S
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Diethyl succinate- 13C4 is the 13C labeled Diethyl succinate[1]. Diethyl succinate (Diethyl Butanedioate) is used at physiological pH and crosses biological membranes, incorporates into cells in tissue culture and is metabolized by the TCA cycle. Diethyl succinate is known to be non-toxic and used in fragrances and flavoring[2].
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- HY-Y0842S2
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Glycine- 13C, 15N is the 13C and 15N labeled Formamide[1]. Formamide is an amide derived from formic acid and has been used as solvent for many ionic compounds.
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- HY-Y0842S3
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Formamide- 15N is the 15N labeled Formamide[1]. Formamide is an amide derived from formic acid and has been used as solvent for many ionic compounds.
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-
- HY-Y0847S
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Potassium thiocyanate- 13C is the 13C labeled Potassium thiocyanate[1].
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-
- HY-Y0989S3
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Acetophenone- 13C is the 13C labeled Acetophenone[1]. Acetophenone is an organic compound with simple structure[2].
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- HY-Y1055S
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Guanine- 13C is the 13C labeled Guanine[1]. Guanine (2-Aminohypoxanthine) is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds.
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- HY-Y1055S1
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Guanine- 13C, 15N2 is the 13C and 15N labeled Guanine[1]. Guanine (2-Aminohypoxanthine) is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds.
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- HY-Y1093S1
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Ethyl acetoacetate- 13C4 is the 13C labeled Ethyl acetoacetate[1]. Ethyl acetoacetate (Ethyl acetylacetate) is an ester widely used as an intermediate in the synthesis of many varieties of compounds[2][3][4]. Ethyl acetoacetate is an inhibitor of bacterial biofilm[5].
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- HY-Y1093S3
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Ethyl acetoacetate- 13C is the 13C labeled Ethyl acetoacetate[1]. Ethyl acetoacetate (Ethyl acetylacetate) is an ester widely used as an intermediate in the synthesis of many varieties of compounds[2][3][4]. Ethyl acetoacetate is an inhibitor of bacterial biofilm[5].
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- HY-Y1117S1
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Melamine-13C3 is the 13C labeled Melamine[1]. Melamine is a metabolite of cyromazine. Melamine is a intermediate for the synthesis of melamine resin and plastic materials[2].
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- HY-Y1169S1
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Fmoc-Asp(OtBu)-OH- 13C4, 15N is the 13C and 15N labeled Fmoc-Asp(OtBu)-OH[1]. Fmoc-Asp(OtBu)-OH (4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-L-aspartate) is a aspartate derivative containing amine protecting group Fmoc. Fmoc-Asp(OtBu)-OH can be used for peptide synthesis[2].
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- HY-Y1213S
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1 Publications Verification
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Carbon- 13C is the 13C labeled Carbon[1].
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- HY-Y1220S
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Potassium carbonate- 13C is the 13C labeled Potassium carbonate[1].
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- HY-Y1352S
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Potassium cyanate- 13C is the 13C labeled Potassium cyanate[1].
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- HY-Y1352S1
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Potassium cyanate- 13C, 15N is the 13C and 15N labeled Potassium cyanate[1].
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- HY-Y1636S1
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Fmoc-Arg(Pbf)-OH- 13C6 is the 13C labeled Fmoc-Arg(Pbf)-OH[1]. Fmoc-Arg(Pbf)-OH is an arginine derivative containing amine protecting group Fmoc. Fmoc-Arg(Pbf)-OH is a building block for the introduction of Arg into SPPS (Solid-Phase Peptide Synthesis)[2].
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- HY-103447S1
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Zearalenone- 13C18 (Mycotoxin F2- 13C18; Toxin F2- 13C18) is the 13C labeled Zearalenone (HY-103447) . Zearalenone is a mycotoxin produced mainly by fungi belonging to the genus Fusarium in foods and feeds. Possess oestrogenic activity in pigs, cattle and sheep, with low acute toxicity. Causes precocious development of mammae and other estrogenic effects in young gilts .
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- HY-N6779S
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Patulin- 13C7 (Terinin- 13C7) is the 13C labeled Patulin (HY-N6779) . Patulin (Terinin) is a mycotoxin produced by fungi including the Aspergillus, Penicillium, and Byssochlamys species, is suspected to be clastogenic, mutagenic, teratogenic and cytotoxic. Patulin induces autophagy-dependent apoptosis through lysosomal-mitochondrial axis, and causes DNA damage .
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- HY-152072S
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Deoxynivalenol- 13C15 is the 13C labeled Deoxynivalenol .
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- HY-N6685S1
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3-Acetyldeoxynivalenol- 13C17 is the 13C labeled 3-Acetyldeoxynivalenol (HY-N6685) . 3-Acetyldeoxynivalenol, a trichothecene mycotoxin deoxynivalenol (DON) acetylated derivative , is a blood-brain barrier (BBB) permeable mycotoxin .
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- HY-N6683S1
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15-Acetyl-deoxynivalenol- 13C17 is the 13C labeled 15-Acetyl-deoxynivalenol (HY-N6683) . 15-Acetyl-deoxynivalenol is a highly toxic trichothecene found in cereals, and a metabolite of deoxynivalenol, exhibits toxicity to HepG2 cells .
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- HY-B0421S2
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Mycophenolic acid-13C17 (Mycophenolate-13C17) is the 13C labeled Mycophenolic acid (HY-B0421). Mycophenolic acid is a potent uncompetitive inosine monophosphate dehydrogenase (IMPDH) inhibitor with an EC50 of 0.24 μM. Mycophenolic acid demonstrates antiviral effects against a wide range of RNA viruses including influenza. Mycophenolic acid is an immunosuppressive agent. Antiangiogenic and antitumor effects.
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- HY-N6801S
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Nivalenol- 13C15 is the 13C labeled Nivalenol (HY-N6801) . Nivalenol, classified as type B trichotecenes toxins produced by Fusarium graminearum, is a fungal metabolite present in agricultural product . Nivalenol induces cell death through caspase-dependent mechanisms and via the intrinsic apoptotic pathway. Nivalenol affects the immune system, causes emesis, growth retardation, reproductive disorders and has a haematotoxic/myelotoxic effect .
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- HY-N6746S1
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Citrinin- 13C13 (NSC 186- 13C13) is the 13C labeled Citrinin (HY-N6746). Citrinin (NSC 186) is a mycotoxin that causes food contamination and has different toxic effects. Citrinin is an effective oral anticancer agent. Citrinin has various regulatory effects on mouse immune system, including regulating the number of immune cells, inducing apoptosis and autophagy of immune cells, altering toll-like receptor expression and cytokine production. Citrinin can induce oxidative stress and lead to early apoptosis of oocytes. Low doses of Citrinin have neuroprotective effects against glutamate-induced excitotoxicity in rat cortical neurons. In addition, Citrinin also has antibacterial activity .
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- HY-N6719S
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Fumonisin B1- 13C34 is the 13C labeled Fumonisin B1 (HY-N6719) . Fumonisin B1 is a mycotoxin produced from Fusarium moniliforme. Fumonisin B1 is a potent inhibitor of sphingosine N-acyltransferase (ceramide synthase) and disrupts de novo sphingolipid biosynthesis. Fumonisin B1 is the most abundant and toxic fumonisin .
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- HY-N6723S
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Fumonisin B2- 13C34 is the 13C labeled Fumonisin B2 (HY-N6723) . Fumonisin B2, a mycotoxin produced by Fusarium moniliforme in various grains, is a potent inhibitor of sphingosine N-acyltransferase (ceramide synthase) and disrupts de novo sphingolipid biosynthesis .
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- HY-N6726S
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Fumonisin B3- 13C34 is the 13C labeled Fumonisin B3 (HY-N6726) . Fumonisin B3 is a mycotoxin derived from fusarium fungi, a member of fumonisins .
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- HY-A0181S1
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Adenosine monophosphate- 15N5 (dilithium) is the 15N labeled Adenosine monophosphate (HY-A0181) . Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction .
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- HY-N6786S
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Ochratoxin B- 13C20 is 13C-labeled Ochratoxin B (HY-N6786). Ochratoxin B, a secondary metabolite of Aspergillus ochraceus, is the nonchlorinated analogue of the mycotoxin Ochratoxin A. Ochratoxin B has been shown to reduce the toxic effects of Ochratoxin A, and it is one of the most potent renal carcinogens in rodents .
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- HY-108213S
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Inosinic acid- 13C10, 15N4 dilithium (5'-IMP-13C10,15N4 (dilithium); IMP-13C10,15N4 (dilithium); Inosine 5'-(dihydrogen phosphate)-13C10,15N4 (dilithium)) is 13C- and 15N-labeled Inosinic acid (HY-108213). Inosinic acid is an endogenous metabolite .
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- HY-108213S1
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Inosinic acid- 15N4 dilithium (5'-IMP-15N4 (dilithium); IMP-15N4 (dilithium); Inosine 5'-(dihydrogen phosphate)-15N4 (dilithium)) is 15N-labeled Inosinic acid (HY-108213). Inosinic acid is an endogenous metabolite .
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- HY-13948BS
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Angiotensin II human- 13C6, 15N TFA (Ang II- 13C6, 15N TFA) is 13C- and 15N-labeled Angiotensin II human (TFA) (HY-13948B). Angiotensin II human (Angiotensin II) TFA is a vasoconstrictor and a major bioactive peptide of the renin/angiotensin system. Angiotensin II human TFA plays a central role in regulating human blood pressure, which is mainly mediated by interactions between Angiotensin II and the G-protein-coupled receptors (GPCRs) Angiotensin II type 1 receptor (AT1R) and Angiotensin II type 2 receptor (AT2R). Angiotensin II human TFA stimulates sympathetic nervous stimulation, increases aldosterone biosynthesis and renal actions .
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- HY-N0055S
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Chlorogenic acid- 13C3 (Heriguard- 13C3; NSC-407296- 13C3) is 13C- and 15N-labeled Chlorogenic acid (HY-N0055). Chlorogenic acid is a major phenolic compound in Lonicera japonica Thunb.. It plays several important and therapeutic roles such as antioxidant activity, antibacterial, hepatoprotective, cardioprotective, anti-inflammatory, antipyretic, neuroprotective, anti-obesity, antiviral, anti-microbial, anti-hypertension .
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- HY-P5168S
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GPSVFPLAPSSK- 13C6 is the 13C labeled GPSVFPLAPSSK. GPSVFPLAPSSK is an IgG1 signature peptide of anti-SARS-CoV-2 antibodies. GPSVFPLAPSSK can be used for the quantification of the specific isolation of anti-SARS-CoV-2 antibodies .
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- HY-126373S1
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SN-38 glucuronide- 13C6 is the 13C labeled SN-38 glucuronide (HY-126373) . SN-38 glucuronide is an inactive metabolite of the cancer agent Irinotecan. Irinotecan is a topoisomerase I inhibitor which can be used for researching colon and rectal cancer .
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- HY-P5190S
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RQIK-(Lys-fructosyl)-QTA-(Leu- 13C6, 15N)-VE is the 13C and 15N labeled compound .
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- HY-P5190S1
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RQIK-(Lys-fructosyl)-QTA-(Leu- 13C6, 15N)-VE TFA is the 13C and 15N labeled compound .
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- HY-P5201S
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VTSEGAGLQLQK- 13C6, 15N2 is the 13C and 15N labeled VTSEGAGLQLQK. VTSEGAGLQLQK is an amino acid sequence in the C-terminal region of recombinant human alpha-acid glucosidase (rhGAA). VTSEGAGLQLQK can be used to bind anti-drug antibodies (ADA) in plasma and quantitatively analyze the therapeutic effect .
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- HY-136457S
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2-NP-AHD- 13C3 is the 13C labled 2-NP-AHD (HY-136457) . 2-NP-AHD is a 2-nitrophenyl derivative of AHD (a metabolite of nitrofurans type of antibiotics), can be used as indicator of the illegal usage of nitrofuran agents .
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- HY-B0226S
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Nitrofurazone- 13C, 15N2 (Nitrofural- 13C, 15N2) is the 13C and 15N labled Nitrofurazone (HY-B0226) . Nitrofurazone is a potential antibiotic that can be used topically to treat wounds, burns, ulcers and skin infections to combat various microorganisms and to prepare surfactants . Nitrofurazone may affect the ecosystem function in Marine environment and affect the functional processes of epiphytic fauna .
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- HY-104026S3
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L-Kynurenine- 13C4, 15N-1 is the 13C and 15N labled L-Kynurenine (HY-104026) . L-Kynurenine is a metabolite of the amino acid L-tryptophan. L-Kynurenine is an aryl hydrocarbon receptor agonist.
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- HY-W018772S16
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D-Ribose-1,2- 13C2 is the 13C labled D-Ribose(mixture of isomers) (HY-W018772) . D-Ribose(mixture of isomers) is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose(mixture of isomers) is active in protein glycation, induces NF-κB inflammation in a RAGE-dependent manner .
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- HY-128748S4
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DL-Glyceraldehyde- 13C3 is the 13C labled DL-Glyceraldehyde (HY-128748) . DL-Glyceraldehyde is an organic compound.
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- HY-A0132S12
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N-Acetyl-D-glucosamine- 13C6 (N-Acetyl-2-amino-2-deoxy-D-glucose- 13C6) is the 13C labled N-Acetyl-D-glucosamine (HY-A0132) . N-Acetyl-D-Glucosamine (N-Acetyl-2-amino-2-deoxy-D-glucose) is a monosaccharide derivative of glucose.
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- HY-B1842S
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Fluroxypyr- 13C2 is the 13C labled Fluroxypyr (HY-B1842) . Fluroxypyr is a herbicide .
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- HY-W015824S5
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DL-Aspartic acid- 13C, 15N-1 hydrochloride is the 13C and 15N labeled DL-Aspartic acid.
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- HY-Y0262S1
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Oxalic acid- 13C2 is the deuterium labeled Oxalic acid, 99% (HY-Y0262) . Oxalic Acid is a strong dicarboxylic acid occurring in many plants and vegetables and can be used as an analytical reagent and general reducing agent .
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- HY-W110148S
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Amitrole- 13C, 15N2 is the deuterium labeled Amitrole .
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- HY-W051624S
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(Rac)-2-Aminothiazoline-4-carboxylic acid- 13C, 15N2 is the deuterium labeled 2-Amino-4,5-dihydrothiazole-4-carboxylic acid (HY-W051624) .
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- HY-W040055S
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Neopterin- 13C5 (D-(+)-Neopterin- 13C5; D-erythro-Neopterin- 13C5) is the deuterium labeled Neopterin (HY-W040055) . Neopterin (D-(+)-Neopterin), a catabolic product of guanosine triphosphate (GTM), serves as a marker of cellular immune system activation .
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- HY-P4596S1
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H-Gly-Arg-OH (Arg- 13C6, 15N4) TFA is the deuterium labeled H-Gly-Arg-OH (HY-P4596) .
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- HY-P4596S
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H-Gly-Arg-OH (Arg- 13C6, 15N4) is the deuterium labeled H-Gly-Arg-OH (HY-P4596) .
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- HY-14605S
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Rasagiline- 13C3 ((R)-AGN1135- 13C3; TVP1012- 13C3) mesylate is the deuterium labeled Rasagiline (mesylate) (HY-14605) . Rasagiline (R-AGN1135) mesylate is a highly potent selective irreversible mitochondrial monoamine oxidase (MAO) inhibitor with IC50s of 4.43 nM and 412 nM for rat brain MAO B and A activity, respectively .
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- HY-13417S
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AICAR- 13C2, 15N (Acadesine- 13C2, 15N; AICA Riboside- 13C2, 15N) is the 13C and 15N labeled AICAR (HY-13417) . AICAR (Acadesine) is an adenosine analog and a AMPK activator. AICAR regulates the glucose and lipid metabolism, and inhibits proinflammatory cytokines and iNOS production. AICAR is also an autophagy, YAP and mitophagy inhibitor .
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- HY-133968S1
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24-Methylenecholesterol- 13C (Ostreasterol- 13C) is the 13C labeled 24-Methylenecholesterol (HY-133968) . 24-Methylenecholesterol (Ostreasterol), a natural marine sterol, stimulates cholesterol acyltransferase in human macrophages. 24-Methylenecholesterol possess anti-aging effects in yeast. 24-methylenecholesterol enhances honey bee longevity and improves nurse bee physiology .
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- HY-112537S1
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D-Glucose 6-Phosphate- 13C6 disodium xhydrate is the 13C labeled D-Glucose 6-phosphate (HY-112537) . D-Glucose 6-phosphate is a glucose sugar phosphorylated at the hydroxy group on carbon 6 .
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- HY-100807S1
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Quinolinic acid- 13C7 is the 13C labeled Quinolinic acid (HY-100807) . Quinolinic acid is an endogenous N-methyl-D-aspartate (NMDA) receptor agonist synthesized from L-tryptophan via the kynurenine pathway and thereby has the potential of mediating N-methyl-D-aspartate neuronal damage and dysfunction .
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- HY-B0510S3
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Trimethoprim- 13C3 is the deuterium labeled Trimethoprim (HY-B0510) . Trimethoprim is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim has the potential for the research of urinary tract infections, Shigellosis and Pneumocystis pneumonia. Trimethoprim can inhibit infection of Influenza A virus in chick embryo when combinated with zinc .
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- HY-A0090S
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Nitrofurantoin- 13C3 is the 13C labeled Nitrofurantoin (HY-A0090) . Nitrofurantoin is a potent and orally active broad-spectrum beta-lactamase antimicrobial agent. Nitrofurantoin acts as an antibiotic and can be used for the study of urinary tract infections (UTIs), including cystitis and kidney infections .
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- HY-Y1117S2
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Melamine- 15N3, 13C3 is a 13C- and 15N-labeled Melamine (HY-Y1117). Melamine is a metabolite of cyromazine. Melamine is a intermediate for the synthesis of melamine resin and plastic materials .
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- HY-Y0051S
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5-Hydroxymethylfurfural- 13C6 (2-Hydroxymethyl-5-furfural- 13C6; 2-Formyl-5-hydroxymethylfuran- 13C6) is a 13C labeled 5-Hydroxymethylfurfural (HY-Y0051). 5-Hydroxymethylfurfural (2-Hydroxymethyl-5-furfural), derived from Cornus officinalis, inhibits yeast growth and fermentation as stressors.
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- HY-13623S1
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Entecavir- 13C2, 15N (BMS200475- 13C2, 15N; SQ34676- 13C2, 15N) is a 13C- and 15N-labeled Entecavir (HY-13623). Entecavir (SQ 34676; BMS 200475) is a potent and selective inhibitor of HBV, with an EC50 of 3.75 nM in HepG2 cell.
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- HY-138253S
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2′,2′-Difluorodeoxyuridine- 13C, 15N2 (dFdU- 13C, 15N2; 2',2'-Difluoro-2'-deoxyuridine- 13C, 15N2) is a 13C- and 15N-labeled compound.
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- HY-14291S2
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Vildagliptin- 13C5, 15N (LAF237- 13C5, 15N; NVP-LAF 237- 13C5, 15N) is a 13C- and 15N-labeled Vildagliptin (HY-14291). Vildagliptin (LAF237) is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC50 of 3.5 nM in human Caco-2 cells. Vildagliptin possesses excellent oral bioavailability and potent antihyperglycemic activity .
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- HY-17427S2
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Emtricitabine- 13C, 15N2 (BW1592- 13C, 15N2) is a 13C- and 15N-labeled Emtricitabine (HY-17427). Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) with an EC50 of 0.01 μM in PBMC cell. It is an antiviral agent for the treatment of HIV infection.
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- HY-17563S1
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2'-Deoxyguanosine- 13C10, 15N5 (Deoxyguanosine- 13C10, 15N5; Guanine deoxyriboside- 13C10, 15N5) is a 13C- and 15N-labeled 2'-Deoxyguanosine (HY-17563).
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- HY-18341S4
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L-Thyroxine- 13C6-1 (Levothyroxine- 13C6-1; T4- 13C6-1) is a 13C labeled L-Thyroxine (HY-18341). L-Thyroxine (Levothyroxine; T4) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4) .
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- HY-78131S3
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Ibuprofen- 13C6 ((±)-Ibuprofen- 13C6) is a 13C labeled Ibuprofen (HY-78131). Ibuprofen ((±)-Ibuprofen) is a potent, orally active, selective COX-1 inhibitor with an IC50 value of 13 μM. Ibuprofen inhibits cell proliferation, angiogenesis, and induces cell apoptosis. Ibuprofen is a nonsteroidal anti-inflammatory agent and a nitric oxide (NO) donor. Ibuprofen ((±)-Ibuprofen) can be used in the research of pain, swelling, inflammation, infection, immunology, cancers .
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- HY-B0139S
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Flucytosine- 13C, 15N2 (NSC 103805- 13C, 15N2; Ro 2-9915- 13C, 15N2) is a 13C- and 15N-labeled Flucytosine (HY-B0139).
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- HY-B0166S8
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L-Ascorbic acid- 13C6-1 (L-Ascorbate-1; Vitamin C- 13C6-1) is a 13C labeled L-Ascorbic acid (HY-B0166) . L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor . L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells .
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- HY-B1449S10
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Uridine- 13C5 (β-Uridine- 13C5) is a 13C labeled Uridine (HY-B1449). Uridine (β-Uridine) is a nucleoside compound consisting of uracil and a ribose ring, which are linked by a β-N1- glycosyl bond.
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- HY-B1449S9
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Uridine- 13C, 15N2 (β-Uridine- 13C, 15N2) is a 13C- and 15N-labeled Uridine (HY-B1449).
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- HY-P5537S
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ETTVFENLPEK- 13C11, 15N2 (TFA) (ETTVFENLPEK- 13C11, 15N2 (TFA)) is a 13C- and 15N-labeled compound.
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- HY-P5538S
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EPYFGYSGAFK- 13C9, 15N3 (TFA) (EPYFGYSGAFK- 13C9, 15N3 (TFA)) is a 13C- and 15N-labeled compound.
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- HY-W007376S
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Indole-3-carboxaldehyde- 13C (3-Formylindole- 13C) is a 13C labeled Indole-3-carboxaldehyde (HY-W007376). Indole-3-carboxaldehyde (3-Formylindole), a banlangen extract, is the product of the oxidative degradation of indole-3-acetic acid (IAA) by crude enzyme preparations from etiolated pea seedlings. Indole-3-carboxaldehyde (3-Formylindole) is a biochemical used to prepare analogs of the indole phytoalexin cyclobrassinin .
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- HY-W009362AS
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DL-Isocitric acid-13C4 (trisodium hydrate) is a 13C labeled DL-Isocitric acid.
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- HY-W009362S
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DL-Isocitric acid- 13C4 (trisodium salt) is a 13C labeled DL-Isocitric acid (trisodium salt) (HY-W009362). DL-Isocitric acid trisodium salt is an endogenous metabolite. DL-Isocitric acid trisodium salt is a substrate in the citric acid cycle. DL-Isocitric acid trisodium salt can be used as a marker for determining the composition of isocitrates in fruit products, including fruit juices.
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- HY-13078S
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Cobimetinib- 13C6 (GDC-0973- 13C6; XL518- 13C6) racemate is the deuterium labeled Cobimetinib (racemate) (HY-13078) . Cobimetinib racemate (GDC-0973 racemate; XL518 racemate) is the racemate of Cobimetinib. Cobimetinib is a potent and selective MEK inhibitor .
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- HY-B0221S
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Amphotericin B- 13C6 is 13C labeled Amphotericin B (HY-B0221). Amphotericin B is a polyene antifungal agent against a wide variety of fungal pathogens. It binds irreversibly to ergosterol, resulting in disruption of membrane integrity and ultimately cell death.
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- HY-W777535S
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Naphthalene- 13C6 is 13C labeled Naphthalene-13C10 (HY-W777535).
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- HY-B1654S
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Flavin adenine dinucleotide- 13C5 (FAD- 13C5) ammonium is 13C labeled Flavin adenine dinucleotide (HY-B1654). Flavin adenine dinucleotide (FAD) is a redox cofactor, more specifically a prosthetic group of a protein, involved in several important enzymatic reactions in metabolism.
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- HY-W777456
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Phenanthrene- 13C6 is 13C labeled Phenanthrene-13C6 (HY-W777456).
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- HY-W777457
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Anthracene- 13C6 (Anthracin- 13C6) is 13C labeled Anthracene-13C6 (HY-W777457).
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- HY-W777535
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Naphthalene- 13C10 is 13C labeled Naphthalene-13C10 (HY-W777535).
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- HY-N0349S1
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Methyl Paraben- 13C6 (Methyl 4-hydroxybenzoate- 13C6) is a 13C labeled Methyl Paraben (HY-N0349) . Methyl Paraben, isolated from the barks of Tsuga dumosa the methyl ester of p-hydroxybenzoic acid, is a standardized chemical allergen. Methyl Paraben is a stable, non-volatile compound used as an antimicrobial preservative in foods, agents and cosmetics. The physiologic effect of Methyl Paraben is by means of increased histamine release, and cell-mediated immunity .
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- HY-W013636S3
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2-Ketoglutaric acid- 13C (Alpha-Ketoglutaric acid- 13C) is a 13C labeled 2-Ketoglutaric acid (HY-W013636) . 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC50=15 mM) .
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- HY-A0181BS
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1 Publications Verification
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Adenosine monophosphate-13C10,15N5 (disodium) is the sodium salt form of Adenosine monophosphate-13C10,15N5. Adenosine monophosphate is a key cellular metabolite that regulates energy homeostasis and signal transduction .
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- HY-B0863S3
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Glyphosate- 13C2, 15N is the 13C and 15N labled Glyphosate (HY-B0863). Glyphosate is an herbicidal derivative of the amino acid glycine. Glyphosate targets and blocks a plant metabolic pathway not found in animals, the shikimate pathway, required for the synthesis of aromatic amino acids in plants .
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- HY-N0832S1A
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L-Histidine- 13C6, 15N3 hydrochloride is the 13C and 15N labled L-Histidine (HY-N0832). L-Histidine is an essential amino acid for infants. L-Histidine is an inhibitor of mitochondrial glutamine transport.
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- HY-B0228S11
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Adenosine- 15N5 (Adenine riboside- 15N5; D-Adenosine- 15N5) is the 15N labled Adenosine (HY-B0228). Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation .
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- HY-12726S1
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Liproxstatin-1- 15N is the 15N labled Liproxstatin-1 (HY-12726). Liproxstatin-1 is a potent ferroptosis inhibitor and inhibits ferroptotic cell death (IC50=22 nM) .
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- HY-12726S
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Liproxstatin-1- 13C6 is the 13C labled Liproxstatin-1 (HY-12726). Liproxstatin-1 is a potent ferroptosis inhibitor and inhibits ferroptotic cell death (IC50=22 nM) .
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- HY-B0141S7
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rel-Estradiol-13C6 is a isomeride of Estradiol (HY-B0141) .
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- HY-W016814S
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(Z)-Aconitic acid- 13C6 is the 13C-labeled (Z)-Aconitic acid (HY-W016814). (Z)-Aconitic acid- 13C6 (cis-Aconitic acid) is the cis-isomer of Aconitic acid. (Z)-Aconitic acid- 13C6 (cis-Aconitic acid) is an intermediate in the tricarboxylic acid cycle produced by the dehydration of citric acid.
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- HY-W778203
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Glycolic acid- 13C2 is the 13C-labeled Glycolic acid (HY-W015967). Glycolic acid- 13C2 is an inhibitor of tyrosinase, suppressing melanin formation and lead to a lightening of skin colour.
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- HY-N7745S2
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Glucosylsphingosine- 13C6 is an active compound. Glucosylsphingosine- 13C6 can be used for various studies .
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- HY-A0132S13
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N-Acetyl-D-glucosamine- 13C8, 15N is 13C and 15N labeled N-Acetyl-D-glucosamine (HY-A0132). N-Acetyl-D-glucosamine is a monosaccharide derivative of glucose.
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- HY-B1342S3
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Vitamin A- 13C3 (Vitamin A1- 13C3; all-trans-Retinol- 13C3) is a 13C-labeled Vitamin A/Vitamin A (HY-B1342). Vitamin A is an endogenous metabolite.
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- HY-D0187S4
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L-Glutathione reduced- 13C (GSH- 13C; γ-L-Glutamyl-L-cysteinyl-glycine- 13C) is 13C-labeled L-Glutathione reduced (HY-D0187). L-Glutathione reduced is an endogenous antioxidant and oxygen free radical scavenger.
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- HY-D0187S6
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L-Glutathione reduced- 15N (GSH- 15N; γ-L-Glutamyl-L-cysteinyl-glycine- 15N) is 15N-labeled L-Glutathione reduced (HY-D0187). L-Glutathione reduced (GSH; γ-L-Glutamyl-L-cysteinyl-glycine) is an endogenous antioxidant that scavenges oxygen free radicals.
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- HY-N7092S22
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D-Fructose- 13C3 is 13C-labeled D-Fructose (HY-N7092). D-Fructose (D(-)-Fructose) is a natural monosaccharide found in many plants.
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- HY-N7092S23
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D-Fructose- 13C3-1 is 13C-labeled D-Fructose (HY-N7092). D-Fructose (D(-)-Fructose) is a natural monosaccharide found in many plants.
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- HY-N7092S24
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D-Fructose- 13C4 is 13C-labeled D-Fructose (HY-N7092). D-Fructose (D(-)-Fructose) is a natural monosaccharide found in many plants.
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- HY-W751098
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Aldosterone- 13C3 is a 13C-labeled Aldosterone (HY-113313). Aldosterone is a primary mineralocorticoid and steroid hormone.
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- HY-W751099
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Corticosterone- 13C3 is a 13C-labeled corticosterone (HY-B1618). Corticosterone (17-Deoxycortisol) is an orally available glucocorticoid that can regulate limbic system neurons and has good immunosuppressive activity.
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- HY-W770183
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Uric acid- 13C3 is 13C-labeled Uric acid (HY-B2130). Uric acid is the end product of purine metabolism in the human body. Uric acid can scavenge reactive oxygen species (ROS), such as singlet oxygen and peroxynitrite, and inhibit lipid peroxidation.
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- HY-112675S
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4-Octyl itaconate- 13C5-1 is 13C-labeled 4-Octyl itaconate (HY-112675). Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.
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- HY-W015851S2
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(R)-3-Hydroxybutanoic acid-13C4 (sodium) is an active compound. (R)-3-Hydroxybutanoic acid-13C4 (sodium) can be used for kinds of research.
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- HY-13407S
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Gossypol-13C2 (BL 193-13C2) is an active compound. Gossypol-13C2 can be used for kinds of research.
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- HY-150651S
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Uridine 5′-monophosphate- 15N2 (sodium) is the 15N labeled Uridine 5′-monophosphate sodium[1].
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- HY-B0190S1
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Nafamostat formate salt- 13C6 is the 13C labeled Nafamostat. Nafamostat, a synthetic serine protease inhibitor, is an anticoagulant. Nafamostat supresses T cell auto-reactivity by decreasing granzyme activity and CTL cytolysis. Nafamostat blocks activation of SARS-CoV-2 .
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- HY-B1462S1
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Chlorzoxazone- 13C is the 13C labeled Chlorzoxazone[1]. Chlorzoxazone is a centrally acting muscle relaxant used to treat muscle spasm and the resulting pain or discomfort[2].
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- HY-W334800S2
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(2S,6S)-2,6-Diaminoheptanedioic acid- 13C7 (L-threo-2,6-Diaminopimelic acid- 13C7) is 13C-labeled (2S,6S)-2,6-diaminoheptanedioic acid (HY-W334800).
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- HY-W334800S
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(2S,6S)-2,6-Diaminoheptanedioic acid- 13C7, 15N2 (L-threo-2,6-Diaminopimelic acid- 13C7, 15N2) is 13C and 15N-labeled (2S,6S)-2,6-diaminoheptanedioic acid (HY-W334800).
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- HY-W334800S1
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(2S,6S)-2,6-Diaminoheptanedioic acid- 15N2 (L-threo-2,6-Diaminopimelic acid- 15N2) is 15N labeled (2S,6S)-2,6-diaminoheptanedioic acid (HY-W334800).
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- HY-128746S
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2,6-Diaminoheptanedioic acid- 13C7, 15N2 is 13C and 15N-labeled 2,6-Diaminoheptanedioic acid (HY-128746). 2,6-Diaminoheptanedioic acid is an endogenous metabolite.
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- HY-128746S1
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2,6-Diaminoheptanedioic acid- 15N2 is 15N labeled 2,6-Diaminoheptanedioic acid (HY-128746). 2,6-Diaminoheptanedioic acid is an endogenous metabolite.
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- HY-W393970S2
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2′-Deoxyguanosine 5′-monophosphate- 13C10 (5'-Deoxyguanylic acid- 13C10) dilithium is 13C-labeled 2′-Deoxyguanosine 5′-monophosphate (HY-W393970).
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- HY-W393970S3
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2′-Deoxyguanosine 5′-monophosphate- 13C10, 15N5 (5'-Deoxyguanylic acid- 13C10, 15N5) dilithium is 13C and 15N-labeled 2′-Deoxyguanosine 5′-monophosphate (HY-W393970).
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- HY-W393970S4
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2′-Deoxyguanosine 5′-monophosphate- 15N5 (5'-Deoxyguanylic acid- 15N5) dilithium is 15N labeled 2′-Deoxyguanosine 5′-monophosphate (HY-W393970).
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- HY-W040329S1
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2'-Deoxyadenosine- 13C10 is 13C-labeled 2'-Deoxyadenosine (HY-W040329). 2'-Deoxyadenosine is a nucleoside adenosine derivative, pairing with deoxythymidine (T) in double-stranded DNA.
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- HY-W040329S
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2'-Deoxyadenosine- 13C10, 15N5 is 13C and 15N-labeled 2'-Deoxyadenosine (HY-W040329). 2'-Deoxyadenosine is a nucleoside adenosine derivative, pairing with deoxythymidine (T) in double-stranded DNA.
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- HY-W016009S3
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2'-Deoxyadenosine-5'-monophosphate- 13C10 dilithium is 13C-labeled 2'-Deoxyadenosine-5'-monophosphate (HY-W016009). 2′-Deoxyadenosine 5′-monophosphate, a nucleic acid AMP derivative, is a deoxyribonucleotide found in DNA. 2′-Deoxyadenosine 5′-monophosphate can be used to study adenosine-based interactions during DNA synthesis and DNA damage.
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- HY-W016009S4
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2'-Deoxyadenosine-5'-monophosphate- 13C10, 15N5 dilithium is 13C and 15N-labeled 2'-Deoxyadenosine-5'-monophosphate (HY-W016009). 2′-Deoxyadenosine 5′-monophosphate, a nucleic acid AMP derivative, is a deoxyribonucleotide found in DNA. 2′-Deoxyadenosine 5′-monophosphate can be used to study adenosine-based interactions during DNA synthesis and DNA damage.
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- HY-W016009S2
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2'-Deoxyadenosine-5'-monophosphate- 15N5 dilithium is 15N labeled 2'-Deoxyadenosine-5'-monophosphate (HY-W016009). 2′-Deoxyadenosine 5′-monophosphate, a nucleic acid AMP derivative, is a deoxyribonucleotide found in DNA. 2′-Deoxyadenosine 5′-monophosphate can be used to study adenosine-based interactions during DNA synthesis and DNA damage.
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- HY-136648S5
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2'-Deoxyadenosine-5'-triphosphate- 13C10 (dATP- 13C10) dilithium is 13C-labeled 2'-Deoxyadenosine-5'-triphosphate (HY-136648). 2'-Deoxyadenosine-5'-triphosphate (dATP) is a nucleotide used in cells for DNA synthesis (or replication), as a substrate of DNA polymerase.
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- HY-136648S1
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2'-Deoxyadenosine-5'-triphosphate- 13C10, 15N5 (dATP- 13C10, 15N5) dilithium is 13C and 15N-labeled 2'-Deoxyadenosine-5'-triphosphate (HY-136648). 2'-Deoxyadenosine-5'-triphosphate (dATP) is a nucleotide used in cells for DNA synthesis (or replication), as a substrate of DNA polymerase.
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- HY-136648S4
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2'-Deoxyadenosine-5'-triphosphate- 15N5 (dATP- 15N5) dilithium is 15N labeled 2'-Deoxyadenosine-5'-triphosphate (HY-136648). 2'-Deoxyadenosine-5'-triphosphate (dATP) is a nucleotide used in cells for DNA synthesis (or replication), as a substrate of DNA polymerase.
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- HY-D0184S5
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2'-Deoxycytidine- 13C9 (Deoxycytidine- 13C9; Cytosine deoxyriboside- 13C9; Deoxyribose cytidine- 13C9) is 13C-labeled 2'-Deoxycytidine (HY-D0184). 2'-Deoxycytidine, a deoxyribonucleoside, could inhibit biological effects of Bromodeoxyuridine (Brdu).
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- HY-D0184S3
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2'-Deoxycytidine- 13C9, 15N3 (Deoxycytidine- 13C9, 15N3; Cytosine deoxyriboside- 13C9, 15N3; Deoxyribose cytidine- 13C9, 15N3) is 13C and 15N-labeled 2'-Deoxycytidine (HY-D0184). 2'-Deoxycytidine, a deoxyribonucleoside, could inhibit biological effects of Bromodeoxyuridine (Brdu).
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- HY-W009216S1
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2'-Deoxycytidine-5'-monophosphoric acid- 13C9, 15N3 dilithium is 13C and 15N-labeled 2'-Deoxycytidine-5'-monophosphoric acid (HY-W009216). 2'-Deoxycytidine-5'-monophosphoric acid is an endogenous metabolite.
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- HY-17563S2
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2'-Deoxyguanosine- 13C10 (Deoxyguanosine- 13C10; Guanine deoxyriboside- 13C10) is 13C-labeled 2'-Deoxyguanosine (HY-17563). 2'-Deoxyguanosine (Deoxyguanosine) is deoxyguanosine.
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- HY-17563S4
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2'-Deoxyguanosine- 15N5 (Deoxyguanosine- 15N5; Guanine deoxyriboside- 15N5) is 15N labeled 2'-Deoxyguanosine (HY-17563). 2'-Deoxyguanosine (Deoxyguanosine) is deoxyguanosine.
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- HY-134178S
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5-Fluorouridine 5'-triphosphate- 19F is a 19F labeled 5-Fluorouridine 5'-triphosphate.
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- HY-N5134S1
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5'-Guanylic acid- 13C10 (5'-GMP- 13C10 dilithium; 5'-guanosine monophosphate- 13C10) dilithium is 13C-labeled 5'-Guanylic acid (HY-N5134). 5'-Guanylic acid (5'-GMP) is involved in several metabolic disorders, including the AICA-ribosiduria pathway, adenosine deaminase deficiency, adenine phosphoribosyltransferase deficiency (aprt), and the 2-hydroxyglutric aciduria pathway.
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- HY-N5134S5
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5'-Guanylic acid- 13C10, 15N5 (5'-GMP- 13C10, 15N5 dilithium; 5'-guanosine monophosphate- 13C10, 15N5) dilithium is 13C and 15N-labeled 5'-Guanylic acid (HY-N5134). 5'-Guanylic acid (5'-GMP) is involved in several metabolic disorders, including the AICA-ribosiduria pathway, adenosine deaminase deficiency, adenine phosphoribosyltransferase deficiency (aprt), and the 2-hydroxyglutric aciduria pathway.
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- HY-N5134S2
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5'-Guanylic acid- 15N5 (5'-GMP- 15N5 dilithium; 5'-guanosine monophosphate- 15N5) dilithium is 15N labeled 5'-Guanylic acid (HY-N5134). 5'-Guanylic acid (5'-GMP) is involved in several metabolic disorders, including the AICA-ribosiduria pathway, adenosine deaminase deficiency, adenine phosphoribosyltransferase deficiency (aprt), and the 2-hydroxyglutric aciduria pathway.
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- HY-154741S
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6-β-D-Ribofuranosyl-2,4(1H,3H)-pyrimidinedione- 15N2 is 15N labeled (HY-154741).
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- HY-W042357S4
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Ac-rC Phosphoramidite- 13C9 is 13C-labeled Ac-rC Phosphoramidite (HY-W042357). Ac-rC Phosphoramidite is used for the oligoribonucleotide phosphorodithioate modification (PS2-RNA).
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- HY-W042357S6
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Ac-rC Phosphoramidite- 13C9, 15N3 is 13C and 15N-labeled Ac-rC Phosphoramidite (HY-W042357). Ac-rC Phosphoramidite is used for the oligoribonucleotide phosphorodithioate modification (PS2-RNA).
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- HY-W042357S
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Ac-rC Phosphoramidite- 15N is 15N labeled Ac-rC Phosphoramidite (HY-W042357). Ac-rC Phosphoramidite is used for the oligoribonucleotide phosphorodithioate modification (PS2-RNA).
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- HY-W042357S1
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Ac-rC Phosphoramidite- 15N2 is 15N labeled Ac-rC Phosphoramidite (HY-W042357). Ac-rC Phosphoramidite is used for the oligoribonucleotide phosphorodithioate modification (PS2-RNA).
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- HY-W042357S2
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Ac-rC Phosphoramidite- 15N3 is 15N labeled Ac-rC Phosphoramidite (HY-W042357). Ac-rC Phosphoramidite is used for the oligoribonucleotide phosphorodithioate modification (PS2-RNA).
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- HY-B0152S3
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Adenine- 13C5 (6-Aminopurine- 13C5; Vitamin B4- 13C5) is 13C-labeled Adenine (HY-B0152). Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA.
Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis.
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- HY-B0152S2
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Adenine- 13C5,15C5 (6-Aminopurine- 13C5,15C5; Vitamin B4- 13C5,15C5) is 13C-labeled Adenine (HY-B0152). Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis.
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- HY-B0152S4
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Adenine- 15N5 (6-Aminopurine- 15N5; Vitamin B4- 15N5) is 15N labeled Adenine (HY-B0152). Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA.
Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis.
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- HY-A0181S3
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Adenosine monophosphate- 13C10 (AMP- 13C10) dilithium is 13C-labeled Adenosine monophosphate (HY-A0181). Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction.
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- HY-B0228S13
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Adenosine- 13C10 (Adenine riboside- 13C10; D-Adenosine- 13C10) is 13C-labeled Adenosine (HY-B0228). Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation.
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- HY-128417S4
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alpha-D-glucose- 13C6 is 13C-labeled alpha-D-glucose (HY-128417). alpha-D-glucose is an endogenous metabolite.
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- HY-W014375S2
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Arginine- 13C6 hydrochloride is 13C-labeled Arginine (hydrochloride) (HY-W014375). Arginine hydrochloride is an arginine derivative.
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- HY-W014375S4
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Arginine- 13C6, 15N4 hydrochloride is 13C and 15N-labeled Arginine (hydrochloride) (HY-W014375). Arginine hydrochloride is an arginine derivative.
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- HY-B2176S2
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ATP- 13C (Adenosine 5'-triphosphate- 13C) dilithium is 13C-labeled ATP (HY-B2176). ATP (Adenosine 5'-triphosphate) is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation.
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- HY-B2176S6
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ATP- 13C10 (Adenosine 5'-triphosphate- 13C10) dilithium is 13C-labeled ATP (HY-B2176). ATP (Adenosine 5'-triphosphate) is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation.
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- HY-B2176S5
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ATP- 15N5 (Adenosine 5'-triphosphate- 15N5) dilithium is 15N labeled ATP (HY-B2176). ATP (Adenosine 5'-triphosphate) is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation.
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- HY-W009162S1
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Cytidine 5′-monophosphate- 13C9 (5'-Cytidylic acid- 13C9 dilithium; 5'-CMP- 13C9) dilithium is 13C-labeled Cytidine 5'-monophosphate (HY-W009162). Cytidine 5'-monophosphate (5'-Cytidylic acid) is a nucleotide which is used as a monomer in RNA. Cytidine 5'-monophosphate consists of the nucleobase cytosine, the pentose sugar ribose, and the phosphate group.
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- HY-W009162S5
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Cytidine 5′-monophosphate- 13C9, 15N3 (5'-Cytidylic acid- 13C9, 15N3 dilithium; 5'-CMP- 13C9, 15N3) dilithium is 13C and 15N-labeled Cytidine 5'-monophosphate (HY-W009162). Cytidine 5'-monophosphate (5'-Cytidylic acid) is a nucleotide which is used as a monomer in RNA. Cytidine 5'-monophosphate consists of the nucleobase cytosine, the pentose sugar ribose, and the phosphate group.
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- HY-W009162S4
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Cytidine 5′-monophosphate- 15N3 (5'-Cytidylic acid- 15N3 dilithium; 5'-CMP- 15N3) dilithium is 15N labeled Cytidine 5'-monophosphate (HY-W009162). Cytidine 5'-monophosphate (5'-Cytidylic acid) is a nucleotide which is used as a monomer in RNA. Cytidine 5'-monophosphate consists of the nucleobase cytosine, the pentose sugar ribose, and the phosphate group.
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- HY-113400S1
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Cytidine diphosphate- 13C9 dilithium is 13C-labeled Cytidine diphosphate (HY-113400). Cytidine diphosphate is a nucleoside diphosphate that acts as a carrier for phosphorylcholine, diacylglycerol, and other molecules during phospholipid synthesis.
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- HY-113400S2
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Cytidine diphosphate- 13C9, 15N3 dilithium is 13C and 15N-labeled Cytidine diphosphate (HY-113400). Cytidine diphosphate is a nucleoside diphosphate that acts as a carrier for phosphorylcholine, diacylglycerol, and other molecules during phospholipid synthesis.
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- HY-113400S
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Cytidine diphosphate- 15N3 dilithium is 15N labeled Cytidine diphosphate (HY-113400). Cytidine diphosphate is a nucleoside diphosphate that acts as a carrier for phosphorylcholine, diacylglycerol, and other molecules during phospholipid synthesis.
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- HY-125818S3
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Cytidine-5'-triphosphate- 13C9 (Cytidine triphosphate- 13C9 dilithium; 5'-CTP- 13C9) dilithium is 13C-labeled Cytidine-5'-triphosphate (HY-125818). Cytidine 5′-triphosphate (Cytidine triphosphate; 5'-CTP) is a nucleoside triphosphate and serves as a building block for nucleotides and nucleic acids, lipid biosynthesis. Cytidine triphosphate synthase can catalyze the formation of cytidine 5′-triphosphate from uridine 5′-triphosphate (UTP). Cytidine 5′-triphosphate is an essential biomolecule?in the de novo?pyrimidine biosynthetic pathway in?T. gondii.
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- HY-125818S6
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Cytidine-5'-triphosphate- 15N3 (Cytidine triphosphate- 15N3 dilithium; 5'-CTP- 15N3) dilithium is 15N labeled Cytidine-5'-triphosphate (HY-125818). Cytidine 5′-triphosphate (Cytidine triphosphate; 5'-CTP) is a nucleoside triphosphate and serves as a building block for nucleotides and nucleic acids, lipid biosynthesis. Cytidine triphosphate synthase can catalyze the formation of cytidine 5′-triphosphate from uridine 5′-triphosphate (UTP). Cytidine 5′-triphosphate is an essential biomolecule?in the de novo?pyrimidine biosynthetic pathway in?T. gondii.
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- HY-101400S4
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Deoxycytidine triphosphate- 13C9 (dCTP- 13C9 dilithium; 2′-Deoxycytidine-5′-triphosphate- 13C9) dilithium is 13C-labeled Deoxycytidine triphosphate (HY-101400). Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.
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- HY-101400S2
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Deoxycytidine triphosphate- 13C9, 15N3 (dCTP- 13C9, 15N3 dilithium; 2′-Deoxycytidine-5′-triphosphate- 13C9, 15N3) dilithium is 13C and 15N-labeled Deoxycytidine triphosphate (HY-101400). Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.
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- HY-101400S3
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Deoxycytidine triphosphate- 15N3 (dCTP- 15N3 dilithium; 2′-Deoxycytidine-5′-triphosphate- 15N3) dilithium is 15N labeled Deoxycytidine triphosphate (HY-101400). Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.
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- HY-138615S2
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Deoxythymidine-5'-triphosphate- 13C10 (dTTP- 13C10) dilithium is 13C-labeled Deoxythymidine-5'-triphosphate (HY-138615). Deoxythymidine-5'-triphosphate (dTTP) is one of the four nucleoside triphosphates. Deoxythymidine-5'-triphosphate (dTTP) is used in the synthesis of DNA.
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- HY-138615S4
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Deoxythymidine-5'-triphosphate- 13C10, 15N2 (dTTP- 13C10, 15N2) dilithium is 13C and 15N-labeled Deoxythymidine-5'-triphosphate (HY-138615). Deoxythymidine-5'-triphosphate (dTTP) is one of the four nucleoside triphosphates. Deoxythymidine-5'-triphosphate (dTTP) is used in the synthesis of DNA.
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- HY-138615S1
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Deoxythymidine-5'-triphosphate- 15N2 (dTTP- 15N2) dilithium is 15N labeled Deoxythymidine-5'-triphosphate (HY-138615). Deoxythymidine-5'-triphosphate (dTTP) is one of the four nucleoside triphosphates. Deoxythymidine-5'-triphosphate (dTTP) is used in the synthesis of DNA.
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- HY-138616S3
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dGTP- 13C10 (2'-Deoxyguanosine-5'-triphosphate- 13C10) dilithium is 13C-labeled dGTP (HY-138616). dGTP (2'-Deoxyguanosine-5'-triphosphate), a guanosine nucleotide, can be used in deoxyribonucleic acid synthesis. Guanosine nucleotides (GDP, GTP, dGDP, and dGTP) are highly susceptible to oxidative damage to 8-oxo-GDP (8-O-GDP), 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.
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- HY-138616S4
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dGTP- 13C10, 15N5 (2'-Deoxyguanosine-5'-triphosphate- 13C10, 15N5) dilithium is 13C and 15N-labeled dGTP (HY-138616). dGTP (2'-Deoxyguanosine-5'-triphosphate), a guanosine nucleotide, can be used in deoxyribonucleic acid synthesis. Guanosine nucleotides (GDP, GTP, dGDP, and dGTP) are highly susceptible to oxidative damage to 8-oxo-GDP (8-O-GDP), 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.
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- HY-138616S
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dGTP- 15N5 (2'-Deoxyguanosine-5'-triphosphate- 15N5) dilithium is 15N labeled dGTP (HY-138616). dGTP (2'-Deoxyguanosine-5'-triphosphate), a guanosine nucleotide, can be used in deoxyribonucleic acid synthesis. Guanosine nucleotides (GDP, GTP, dGDP, and dGTP) are highly susceptible to oxidative damage to 8-oxo-GDP (8-O-GDP), 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.
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- HY-B2236S1
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DL-Lysine- 13C6 hydrochloride ((±)-2,6-Diaminocaproic acid- 13C6 hydrochloride) is 13C-labeled DL-Lysine (HY-B2236). DL-Lysine is a racemic mixture of the D-Lysine and L-Lysine. Lysine is an α-amino acid that is used in the biosynthesis of proteins.
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- HY-B2236S2
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DL-Lysine- 13C6, 15N2 hydrochloride ((±)-2,6-Diaminocaproic acid- 13C6, 15N2 hydrochloride) is 13C and 15N-labeled DL-Lysine (HY-B2236). DL-Lysine is a racemic mixture of the D-Lysine and L-Lysine. Lysine is an α-amino acid that is used in the biosynthesis of proteins.
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- HY-B2236S3
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DL-Lysine- 15N2 hydrochloride ((±)-2,6-Diaminocaproic acid- 15N2 hydrochloride) is 15N labeled DL-Lysine (HY-B2236). DL-Lysine is a racemic mixture of the D-Lysine and L-Lysine. Lysine is an α-amino acid that is used in the biosynthesis of proteins.
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- HY-W013068S2
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DMT-dT Phosphoramidite- 13C is 13C-labeled DMT-dT Phosphoramidite (HY-W013068). DMT-dT Phosphoramidite is typically used in the synthesis of DNA.
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- HY-Y1055S4
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Guanine- 13C5 is 13C-labeled Guanine (HY-Y1055). Guanine (2-Aminohypoxanthine) is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds.
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- HY-Y1055S2
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Guanine- 13C5, 15N5 is 13C and 15N-labeled Guanine (HY-Y1055). Guanine (2-Aminohypoxanthine) is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds.
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- HY-Y1055S3
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Guanine- 15N5 is 15N labeled Guanine (HY-Y1055). Guanine (2-Aminohypoxanthine) is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds.
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- HY-113066S1
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Guanosine 5'-diphosphate- 13C10 (GDP- 13C10) dilithium is 13C-labeled Guanosine 5'-diphosphate (HY-113066). Guanosine 5'-diphosphate (GDP) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K + channel. Guanosine 5'-diphosphate is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate can be used in the research of inflammation, such as anemia of inflammation (AI).
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- HY-113066S3
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Guanosine 5'-diphosphate- 13C10, 15N5 (GDP- 13C10, 15N5) dilithium is 13C and 15N-labeled Guanosine 5'-diphosphate (HY-113066). Guanosine 5'-diphosphate (GDP) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K + channel. Guanosine 5'-diphosphate is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate can be used in the research of inflammation, such as anemia of inflammation (AI).
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- HY-113225S2
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Guanosine triphosphate- 13C (GTP- 13C) dilithium is 13C-labeled Guanosine triphosphate (HY-113225). Guanosine triphosphate is a native nucleotide. The derivatives of GTP may be used as specific inhibitors against COVID-19.
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- HY-113225S5
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Guanosine triphosphate- 13C10 (GTP- 13C10) dilithium is 13C-labeled Guanosine triphosphate (HY-113225). Guanosine triphosphate is a native nucleotide. The derivatives of GTP may be used as specific inhibitors against COVID-19.
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- HY-113225S3
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Guanosine triphosphate- 15N5 (GTP- 15N5) dilithium is 15N labeled Guanosine triphosphate (HY-113225). Guanosine triphosphate is a native nucleotide. The derivatives of GTP may be used as specific inhibitors against COVID-19.
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- HY-W013724S
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Inosine-5'-diphosphoric acid- 15N4 dilithium is 15N labeled Inosine-5'-diphosphoric acid (disodium) (HY-W013724).
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- HY-N0832S1
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L-Histidine- 13C6, 15N3 is 13C and 15N-labeled L-Histidine (HY-N0832). L-Histidine is an essential amino acid for infants. L-Histidine is an inhibitor of mitochondrial glutamine transport.
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- HY-N0086S2
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N6-Methyladenosine- 13C4 (6-Methyladenosine- 13C4; N-Methyladenosine- 13C4) is 13C-labeled N6-Methyladenosine (HY-N0086). N6-Methyladenosine is the most prevalent internal (non-cap) modification present in the messenger RNA (mRNA) of all higher eukaryotes. N6-Methyladenosine can modifies viral RNAs and has antiviral activities.
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- HY-113061S
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Pseudouridine- 18O is the 18O labeled Pseudouridine (HY-113061). Pseudouridine is an isomer of the nucleoside uridine, and the most abundant modified nucleoside in non-coding RNAs. Pseudouridine in rRNA and tRNA can fine-tune and stabilize the regional structure and help maintain their functions in mRNA decoding, ribosome assembly, processing and translation.
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- HY-W048482S2
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rU Phosphoramidite- 13C9 (DMT-2'O-TBDMS-rU phosphoramidite- 13C9) is 13C-labeled rU Phosphoramidite (HY-W048482). rU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
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- HY-W048482S1
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rU Phosphoramidite- 13C9, 15N2 (DMT-2'O-TBDMS-rU phosphoramidite- 13C9, 15N2) is 13C and 15N-labeled rU Phosphoramidite (HY-W048482). rU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
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- HY-W048482S4
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rU Phosphoramidite- 15N (DMT-2'O-TBDMS-rU phosphoramidite- 15N) is 15N labeled rU Phosphoramidite (HY-W048482). rU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
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- HY-W048482S3
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rU Phosphoramidite- 15N2 (DMT-2'O-TBDMS-rU phosphoramidite- 15N2) is 15N labeled rU Phosphoramidite (HY-W048482). rU Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
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- HY-W392933S3
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Thymidine 5'-monophosphate- 13C10 (Thymidine-5'-phosphate- 13C10) dilithium is 13C-labeled Thymidine 5'-monophosphate (HY-W392933).
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- HY-W392933S4
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Thymidine 5'-monophosphate- 13C10, 15N2 (Thymidine-5'-phosphate- 13C10, 15N2) dilithium is 13C and 15N-labeled Thymidine 5'-monophosphate (HY-W392933).
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- HY-W392933S2
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Thymidine 5'-monophosphate- 15N2 (Thymidine-5'-phosphate- 15N2) dilithium is 15N labeled Thymidine 5'-monophosphate (HY-W392933).
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- HY-N1150S11
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Thymidine- 13C10 (DThyd- 13C10; NSC 21548- 13C10) is 13C-labeled Thymidine (HY-N1150). Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication.
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- HY-113359AS1
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Uridine 5'-diphosphate- 13C9 dilithium is 13C-labeled Uridine 5'-diphosphate (HY-113359). Uridine 5'-diphosphate is a P2Y6 receptor agonist with an EC50 of 0.013 μM for human P2Y6 receptor.
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- HY-113359AS2
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Uridine 5'-diphosphate- 13C9, 15N2 dilithium is 13C and 15N-labeled Uridine 5'-diphosphate (HY-113359). Uridine 5'-diphosphate is a P2Y6 receptor agonist with an EC50 of 0.013 μM for human P2Y6 receptor.
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- HY-113359AS3
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Uridine 5'-diphosphate- 15N2 dilithium is 15N labeled Uridine 5'-diphosphate (HY-113359). Uridine 5'-diphosphate is a P2Y6 receptor agonist with an EC50 of 0.013 μM for human P2Y6 receptor.
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- HY-101981S4
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Uridine 5'-monophosphate- 13C9 (5'- Uridylic acid- 13C9) dilithium is 13C-labeled Uridine 5'-monophosphate (HY-101981). Uridine 5'-monophosphate (5'- Uridylic acid), a monophosphate form of UTP, can be acquired either from a de novo pathway or degradation products of nucleotides and nucleic acids in vivo and is a major nucleotide analogue in mammalian milk.
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- HY-101981S3
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Uridine 5'-monophosphate- 13C9, 15N2 (5'- Uridylic acid- 13C9, 15N2) dilithium is 13C and 15N-labeled Uridine 5'-monophosphate (HY-101981). Uridine 5'-monophosphate (5'- Uridylic acid), a monophosphate form of UTP, can be acquired either from a de novo pathway or degradation products of nucleotides and nucleic acids in vivo and is a major nucleotide analogue in mammalian milk.
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- HY-101981S5
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Uridine 5'-monophosphate- 15N2 (5'-?Uridylic acid- 15N2) dilithium is 15N labeled Uridine 5'-monophosphate (HY-101981). Uridine 5'-monophosphate (5'-?Uridylic acid), a monophosphate form of UTP, can be acquired either from a de novo pathway or degradation products of nucleotides and nucleic acids in vivo and is a major nucleotide analogue in mammalian milk.
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- HY-107372S2
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Uridine triphosphate- 13C9 (UTP- 13C9 dilithium; Uridine 5'-triphosphate- 13C9) dilithium is 13C-labeled Uridine triphosphate (HY-107372). Uridine triphosphate (UTP;Uridine 5'-triphosphate) is a nucleotide that regulates the functions of the pancreas in endocrine and exocrine secretion, proliferation, channels, transporters, and intracellular signaling under normal and disease states.
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- HY-107372S4
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Uridine triphosphate- 15N2 (UTP- 15N2 dilithium; Uridine 5'-triphosphate- 15N2) dilithium is 15N labeled Uridine triphosphate (HY-107372). Uridine triphosphate (UTP;Uridine 5'-triphosphate) is a nucleotide that regulates the functions of the pancreas in endocrine and exocrine secretion, proliferation, channels, transporters, and intracellular signaling under normal and disease states.
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- HY-W768291
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[1-13Cgal]Lactose (monohydrate) is a labelled Lactose Monohydrate.
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- HY-W710540
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Guanidine-15N3 hydrochloride is the 15N-labeled Guanidine Hydrobromide .
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- HY-N0092S4
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Inosine-13C3 is a 13C-labeled Inosine that can be used in pharmacokinetic studies of Inosine. Inosine is an agonist of adenosine receptors A1R and A2AR with anti-inflammatory immunomodulatory, antinociceptive and neuroprotective effects .
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- HY-W753983
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Pyruvic acid-13C is isotype-labeled compound of Pyruvic acid. Pyruvic acid is an intermediate metabolite in the metabolism of carbohydrates, proteins, and fats .
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- HY-W101298S
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(Leu-13C6,15N)-Ile-OH (L-Leucyl-13C6,15N-L-isoleucine) TFA is the deuterium labeled Leu-Ile-OH. Leu-Ile-OH protects against neuronal death by inducing brain-derived neurotrophic factor (BDNF) and glial cell line-derived neurotrophic factor (GDNF) synthesis .
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- HY-111095S1
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D-(-)-Lactic acid-13C ((R)-2-Hydroxypropionic acid-13C) is a 13C-labeled D-Lactic acid. D-(-)-Lactic acid-13C can be used as an internal standard and can also be used in studies such as metabolic tracing.
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- HY-104026S5
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L-Kynurenine-13C10 sulfate hydrate is the C13 labeled L-Kynurenine sulfate hydrate. L-Kynurenine is an aryl hydrocarbon receptor agonist .
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- HY-111095S2
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D-(-)-Lactic acid- 13C-1 is the 13C labeled D-(-)-Lactic acid. D-(-)-Lactic acid is a normal intermediate in the fermentation (oxidation, metabolism) of sugar. D-(-)-Lactic acid is identified to be a competitive inhibitor of ProDH (proline dehydrogenase) in plants .
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- HY-111095S3A
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D-(-)-Lactic acid-13C-2 (sodium) is a sodium. D-(-)-Lactic acid-13C-2 (sodium) can be used for a variety of biochemical studies.
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- HY-P3003S
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Cereulide-13C6 is the 13C6 labeled Cereulide.
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- HY-W008642S
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(Leu-13C6,15N)-Leu-OH TFA is a C13 and N15 labeled Leu-Leu-OH TFA. Leu-Leu-OH, a Leu derivative, is a dipeptide .
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- HY-B0174AS
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Olsalazine- 13C6 is the 13C labeled Olsalazine.
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- HY-W585866S
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Alternariol, methyl ether- 13C15 is a 13C labeled Alternariol, methyl ether.
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- HY-157386S
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8-(o-Fluoro-benzyl)theophylline methylsulfonyl- 13C2 is a 13C labeled 8-(o-Fluoro-benzyl)theophylline methylsulfonyl.
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- HY-N6714S2
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Alternariol- 13C14 is a 13C labeled Alternariol (HY-N6714) .
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- HY-136406S
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Bongkrekic acid-13C28 is the C13 labeled Bongkrekic acid. Bongkrekic acid is a mitochondrial toxin secreted by the bacteria Pseudomonas cocovenenans. Bongkrekic acid specific ligand for mitochondrial adenine nucleotide translocase (ANT) rather than the electron transport chain. Bongkrekic acid has to cross the mitochondrial inner membrane to produce its inhibitory effect on ADP/ATP transport .
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- HY-B0220S3
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Erythromycin- 13C2 is a macrolide antibiotic that can be used to treat respiratory infections, skin infections, and chlamydia infections .
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- HY-B1422S
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9-Aminoacridine-13C6 is the 13C-labeled 9-Aminoacridine(HY-B1422). 9-Aminoacridine, a fluorescent probe, acts as an indicator of pH for quantitative determination of transmembrane pH gradients (inside acidic). 9-Aminoacridine is an antimicrobial. 9-Aminoacridine exerts its antimicrobial activity by interacting with specific bacterial DNA and disrupting the proton motive force in K. pneumoniae. 9-Aminoacridine is a HIV-1 inhibitor and inhibits HIV LTR transcription highly dependent on the presence and location of the amino moiety. 9-Aminoacridine inhibits virus replication in HIV-1 infected cell lines. 9-Aminoacridine is used as a Rifampin (RIF; HY-B0272) adjuvant for the multidrug-resistant K. pneumoniae infections .
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- HY-143704S
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5-Aminosalicylic acid-13C6 hydrochloride?(Mesalamine-13C6 hydrochloride; 5-ASA-13C6 hydrochloride; Mesalazine-13C6 hydrochloride) is the 13C labeled 5-Aminosalicylic Acidhydrochloride. 5-Aminosalicylic acid-13C6 hydrochloride?acts as a PPARγ agonist, and also inhibits p21-activated kinase 1 (PAK1) and NF-κB .
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- HY-W010042S3
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L-Glucose- 13C6 (L-(-)-Glucose- 13C6) is C13-labeled L-Glucose. L-Glucose is an enantiomer of D-glucose. L-Glucose enhances food intake .
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- HY-N0136S1
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(±)-Taxifolin-13C3 ((±)-Dihydroquercetin-13C3) is a derivative of (±)-Taxifolin, labeled with 13C3. (±)-Taxifolin is the racemate of Taxifolin. Taxifolin exhibits important anti-tyrosinase activity. Taxifolin exhibits significant inhibitory activity against collagenase with an IC50 value of 193.3 μM . Taxifolin is an important natural compound with antifibrotic activity. Taxifolin is a free radical scavenger with antioxidant capacity .
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- HY-W777681
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Triflusal-13C6 is a C13-labeled Triflusal. Triflusal is a platelet aggregation inhibitor .
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- HY-B0149S3
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Tranexamic acid- 13C2, 15N (Cyclocapron- 13C2, 15N) is the 13C2 and 15N labeled Tranexamic acid. Tranexamic acid is an antifibrinolytic agent that alleviates liver damage and fibrosis in mouse models of chronic bile duct injury .
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- HY-126050S
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(R)-Pantetheine- 15N (Pantetheine- 15N) is the 15N labeled (R)-Pantetheine (HY-126050). (R)-Pantetheine is the biosynthetic precursor to CoA .
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- HY-B1028S
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Pantethine- 15N2 is the 15N2 labeled Pantethine. Pantethine is an orally active lipid-lowering agent. Pantethine has anti-tumor, anti-inflammatory and anti-SARS-COV virus activities. Pantethine is also a neuroprotective agent. Pantethine can be used in the study of Alzheimer's disease, Parkinson's disease, major depression, systemic sclerosis and pantothenate kinase-related neurodegeneration .
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- HY-N0086S3
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N6-Methyladenosine- 13C3 (6-Methyladenosine- 13C3) is 13C-labeled N6-Methyladenosine (HY-N0086). N6-Methyladenosine is the most prevalent internal (non-cap) modification present in the messenger RNA (mRNA) of all higher eukaryotes. N6-Methyladenosine can modifies viral RNAs and has antiviral activities .
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- HY-W762012S
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Octachlorodibenzo-p-dioxin- 13C12 is Octachlorodibenzo-p-dioxin- 13 C-labeled octachlorodibenzo-p-dioxin- 13C. Octachlorodibenzo-p-dioxin is a widespread environmental pollutant .
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- HY-N0097S4
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Guanosine- 13C10 is the 13C labeled Guanosine (HY-N0097). Guanosine is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. Guanosine possesses anti-HSV activity .
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- HY-W751165
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Uridine-13C9,15N2 (β-Uridine-13C9,15N2) is 13C and 15N labeled Uridine (HY-B1449). Uridine is a glycosylated pyrimidine-analog containing uracil attached to a ribose ring (or more specifically, aribofuranose) via a β-N1-glycosidic bond .
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- HY-N0092S3
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Inosine-13C10,15N4 is 13C and 15N labeled Inosine (HY-N0092). Inosine is an endogenous purine nucleoside produced by catabolism of adenosine. Inosine has anti-inflammatory, antinociceptive, immunomodulatory and neuroprotective effects. Inosine is an agonist for adenosine A1 (A1R) and A2A (A2AR) receptors .
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- HY-B0158S7
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Cytidine- 13C9 (Cytosine β-D-riboside- 13C9; Cytosine-1-β-D-ribofuranoside- 13C9) is 13C labeled Cytidine (HY-B0158). Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catecholamine synthesis, and mitochondrial function .
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- HY-B0183S
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Ellagic acid- 13C12 is 13 C-labeled Ellagic acid (HY-B0183). Ellagic acid is a natural antioxidant and acts as a potent and ATP-competitive inhibitor of CK2 and SHP2, with an IC50 of 40 nM and a Ki of 20 nM .
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- HY-N0097S6
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Guanosine- 13C10, 15N5 is the 13C and 15N labeled Guanosine (HY-N0097). Guanosine (DL-Guanosine) is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. Guanosine possesses anti-HSV activity .
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- HY-15407S3
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Sacubitril-13C4 (AHU-377-13C4) is a 13C-labeled version of Sacubitril (HY-15407). Sacubitril is an orally active inhibitor of neprilysin NEP (IC50=5 nM). Sacubitril is used in research on heart failure, hypertension and COVID-19 .
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- HY-B2221S4
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U-13C Cellulose high DP from maize (high purity) is the 13C labeled Cellulose .
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- HY-B2221S5
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U- 13C Cellulose from broccoli is the 13C labeled Cellulose (HY-B2221). Cellulose is a natural high molecular weight polysaccharide found in many plants and organisms. It is widely used in manufacturing industries, such as in paper making, textiles, food and medicine, etc. As a renewable resource, Cellulose is biodegradable and sustainable, and can also be used to manufacture chemicals such as Cellulose Esters, Cellulose Acetate and Cellulose Nitrate. In addition, Cellulose is often used as a food additive to increase the stability and quality of food .
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- HY-158034S
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U-13C Hemicellulose from potato is the 13C labeled Hemicellulose .
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- HY-B2221S1
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U- 13C Cellulose from chicory is the 13C labeled Cellulose (HY-B2221). Cellulose (Pectin glycosidase) is a natural high molecular weight polysaccharide found in many plants and organisms. It is widely used in manufacturing industries, such as in paper making, textiles, food and medicine, etc. As a renewable resource, Cellulose is biodegradable and sustainable, and can also be used to manufacture chemicals such as Cellulose Esters, Cellulose Acetate and Cellulose Nitrate. In addition, Cellulose is often used as a food additive to increase the stability and quality of food .
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- HY-B2221S
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U- 13C Cellulose high DP from potato is the 13C labeled Cellulose (HY-B2221). Cellulose (Pectin glycosidase) is a natural high molecular weight polysaccharide found in many plants and organisms. It is widely used in manufacturing industries, such as in paper making, textiles, food and medicine, etc. As a renewable resource, Cellulose is biodegradable and sustainable, and can also be used to manufacture chemicals such as Cellulose Esters, Cellulose Acetate and Cellulose Nitrate. In addition, Cellulose is often used as a food additive to increase the stability and quality of food .
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- HY-B2221S3
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U- 13C Cellulose high DP from maize is the 13C labeled Cellulose (HY-B2221). Cellulose (Pectin glycosidase) is a natural high molecular weight polysaccharide found in many plants and organisms. It is widely used in manufacturing industries, such as in paper making, textiles, food and medicine, etc. As a renewable resource, Cellulose is biodegradable and sustainable, and can also be used to manufacture chemicals such as Cellulose Esters, Cellulose Acetate and Cellulose Nitrate. In addition, Cellulose is often used as a food additive to increase the stability and quality of food .
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- HY-W653925
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(Aminomethyl)phosphonic acid- 13C, 15N is 13C and 15N-labeled Hexachlorobenzene[1].
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- HY-W718796
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DL-Serine- 15N is 15N-labeled DL-Serine (HY-Y0507) DL-Serine, a fundamental metabolite, is a mixture of D-Serine and L-Serine. DL-Serine has antiviral activity against the multiplication of tobacco mosaic virus (TMV).
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- HY-23506S
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1-Aminoimidazolidine-2,4-dione- 13C3 is 13C labeled 1-Aminoimidazolidine-2,4-dione.
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- HY-N0294S1
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Protocatechuic acid- 13C7 is 13C labeled Protocatechuic acid. Protocatechuic acid is a phenolic compound which exhibits neuroprotective effect.
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- HY-A0084S1
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Procainamide- 13C2 hydrochloride is 13C labeled Procainamide. Procainamide hydrochloride is an antiarrhythmic agent used in the study of cardiac arrhythmias.
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- HY-19717S
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DCVC- 13C3, 15N is 15N and 13C labeled DCVC. DCVC (S-[(1E)-1,2-Dichloroethenyl]-L-cysteine) is a bioactive metabolite of trichloroethylene (TCE). DCVC inhibits pathogen-stimulated pro-inflammatory cytokines IL-1β, IL-8, and TNF-α release from tissue cultures .
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- HY-Y0383S2
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Dimethyl terephthalate- 13C2-1 is 13C labeled Dimethyl terephthalate.
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- HY-W017522S6
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Adipic acid- 13C2 is 13C labeled Adipic acid. Adipic acid is found to be associated with HMG-CoA lyase deficiency, carnitine-acylcarnitine translocase deficiency, malonyl-Coa decarboxylase deficiency, and medium Chain acyl-CoA dehydrogenase deficiency, which are inborn errors of metabolism.
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- HY-W747621
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Ethyl formate- 13C is 13C labeled Ethyl formate.
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- HY-W280531S1
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DNSAH- 15N2 is 15N labeled DNSAH.
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- HY-W768338
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Sucrose- 13C is 13C labeled Sucrose. Sucrose (D-(+)-Saccharose) is a disaccharide which is composed of two monosaccharides, glucose and fructose. Sucrose?can be applied in some animal models, including metabolic disease, obesity,?diet on preference,?and diabetes, et al .
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- HY-W768340
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Sucrose- 13C6-1 is 13C labeled Sucrose. Sucrose (D-(+)-Saccharose) is a disaccharide which is composed of two monosaccharides, glucose and fructose. Sucrose?can be applied in some animal models, including metabolic disease, obesity,?diet on preference,?and diabetes, et al .
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- HY-W067028S
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Semicarbazide- 13C, 15N2 hydrochloride is 15N and 13C labeled Semicarbazide.
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- HY-B0124S1
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Zonisamide- 13C2, 15N is deuterated labeled Zonisamide.
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- HY-B1511S
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Cyclic AMP- 13C5 is a deuterated cyclic AMP.
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- HY-N6692S
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Diacetoxyscirpenol- 13C19 is 13C labeled 2-Acetylfuran (HY-W015912). 2-Acetylfuran (2-Furyl methyl ketone), an important flavour compound or intermediate in foods, is isolated from essential oils, sweet corn products, fruits and flowers. 2-Acetylfuran also can be formed from glucose and glycine by Maillard reaction. 2-Acetylfuran can be used to synthesis Cefuroxime .
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- HY-N6715S
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Tenuazonic acid- 13C10 is 13C labeled 2,6-Dimethylpyrazine (HY-W040790). 2,6-Dimethylpyrazine is a key aroma compound in Boletus edulis .
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- HY-N6725S
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Sterigmatocystine- 13C18 is 13C labeled 2,6-Dimethoxyphenol (HY-W003972). 2,6-Dimethoxyphenol is a phenolic compound that is extensively used for the measurement of laccase activity .
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- HY-N6739S
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Beauvericin- 13C45 is 13C labeled 2,5-Dimethylpyrazine (HY-34439). 2,5-Dimethylpyrazine is an endogenous metabolite.
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- HY-N6745S
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Citreoviridin- 13C23 is 13C labeled 2,3-Pentanedione (HY-W012998). 2,3-Pentanedione is a common constituent of synthetic flavorings and is used to impart a butter, strawberry, caramel, fruit, rum, or cheese flavor in beverages, ice cream, candy, baked goods, gelatins, and puddings. 2,3-Pentanedione also occurs naturally as a fermentation product in beer, wine, and yogurt and is releasedduring roasting of coffee beans .
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- HY-W050154S
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Kojic acid- 13C6 is 13C labeled 2,3-Pentanedione (HY-W012998). 2,3-Pentanedione is a common constituent of synthetic flavorings and is used to impart a butter, strawberry, caramel, fruit, rum, or cheese flavor in beverages, ice cream, candy, baked goods, gelatins, and puddings. 2,3-Pentanedione also occurs naturally as a fermentation product in beer, wine, and yogurt and is releasedduring roasting of coffee beans .
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- HY-A0003S2
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Lenalidomide- 13C5, 15N is 15N and 13C labeled Lenalidomide (HY-A0003). Lenalidomide (CC-5013), a derivative of Thalidomide, acts as molecular glue. Lenalidomide is an orally active immunomodulator. Lenalidomide (CC-5013) is a ligand of ubiquitin E3 ligase cereblon (CRBN), and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide (CC-5013) specifically inhibits growth of mature B-cell lymphomas, including multiple myeloma, and induces IL-2 release from T cells .
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- HY-Y0921S3
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(±)-1,2-Propanediol- 13C3 is 13C labeled (±)-1,2-Propanediol (HY-Y0921). (±)-1, 2-propanediol (1,2-(RS)-Propanediol) is an aliphatic alcohol that is often used as an excipient in many active molecular preparations to increase the solubility and stability of the active molecule. (±)-1, 2-propanediol can affect the neurobehavior of zebrafish .
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- HY-14164S1
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Zileuton- 13C2, 15N is 15N and 13C labeled Zileuton (HY-14164). Zileuton is a potent and selective inhibitor of 5-lipoxygenase with antiasthmatic properties.
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- HY-B0375S1
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Argatroban- 13C6 hydrochloride is 13C labeled Argatroban (HY-B0375). Argatroban (MD-805) is a direct, selective thrombin inhibitor.
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- HY-19657S
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Oxypurinol- 13C, 15N2 is 15N and 13C labeled Oxypurinol (HY-19657). Oxipurinol (Oxipurinol), the major active metabolite of Allopurinol, is an inhibitor of xanthine oxidase. Oxipurinol can be used to regulate blood urate levels and treat gout .
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- HY-109120S1
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Odevixibat- 13C6 is 13C labeled Odevixibat (HY-109120). Odevixibat (A4250) is a selective and orally active ileal apical sodium-dependent bile acid transporter (ASBT) inhibitor. Odevixibat decreases cholestatic liver and bile duct injury in mice model. Odevixibat has the potential for the treatment of primary biliary cirrhosis .
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- HY-113420S2
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11-Dehydro-thromboxane B2- 13C5 is 13C labeled 11-Dehydro-thromboxane B2 (HY-113420). 11-Dehydro-thromboxane B2 is a platelet hemagglutinin. Thromboxane inhibition was assessed by urinary excretion levels of 11-Dehydro-thromboxane B2. 11-Dehydro-thromboxane B2 can be used in the study of atherosclerotic thrombosis .
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- HY-10984S3
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Pomalidomide- 15N, 13C5 is 15N and 13C labeled Pomalidomide (HY-10984). Pomalidomide, the third-generation immunomodulatory agent, acts as molecular glue. Pomalidomide interacts with the E3 ligase cereblon and induces degradation of essential Ikaros transcription factors.
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- HY-17416AS1
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Guanfacine- 15N3, 13C2 is 15N and 13C labeled Guanfacine (HY-17416A). Guanfacine is an orally active noradrenergic α2A agonist and has high selective for the α2A receptor subtype. Guanfacine has effects in producing hypotension and sedation. Guanfacine can be used for the research of a variety of prefrontal cortex (PFC) cognitive disorders, including tourette's syndrome and attention deficit hyperactivity disorder (ADHD) .
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- HY-154773S
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Artesunate- 13C4 is 13C labeled Artesunate.
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- HY-B0271S1
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Pyrazinamide- 13C, 15N is 15N and 13C labeled Pyrazinamide (HY-B0271). Pyrazinamide (Pyrazinecarboxamide; Pyrazinoic acid amide) is a potent and orally active antitubercular antibiotic. Pyrazinamide is a proagent that is converted to the active form pyrazinoic acid (POA) by PZase/nicotinamidase encoded by the pncA gene in M. tuberculosis.
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- HY-154814S
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Monohydroxy-3-butenyl-mercapturic acid- 13C3, 15N sodium is 15N and 13C labeled Monohydroxy-3-butenyl-mercapturic acid.
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- HY-12956S2
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Dinoprost- 13C5 is 13C labeled Dinoprost (HY-12956). Dinoprost (Prostaglandin F2α) is an orally active, potent prostaglandin F (PGF) receptor (FP receptor) agonist. Dinoprost is a luteolytic hormone produced locally in the endometrial luminal epithelium and corpus luteum (CL). Dinoprost plays a key role in the onset and progression of labour .
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- HY-B0347S3
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Lacidipine- 13C4 is 13C labeled Lacidipine (HY-B0347). Lacidipine is an orally active and highly selective L-type calcium channel blocker that acts on smooth muscle calcium channels, primarily dilates peripheral arteries, reduces peripheral resistance, and has long-lasting anti-hypertensive activity. Lacidipine protects HKCs from apoptosis induced by ATP depletion and recovery by modulating the caspase-3 pathway. Lacidipine can be used in studies of hypertension, atherosclerosis and acute kidney injury (AKI) .
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- HY-B0111RS
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Drospirenone- 13C3 is 13C labeled Drospirenone. Drospirenone (Dihydrospirorenone) is a synthetic progesterone that is an analog of Spironolactone .
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- HY-B0139AS
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Flucytosine- 15N3 hydrochloride is 15N labeled Flucytosine.
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- HY-154746S
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3-HPMA Potassium Salt-3- 13C3, 15N is 15N and 13C labeled 3-HPMA Potassium Salt-3.
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- HY-113209S2
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8-Isoprostaglandin F2α- 13C5 is 13C labeled 8-Isoprostaglandin F2α (HY-113209). 8-Isoprostaglandin F2α is an isoprostane produced by the non-enzymatic peroxidation of arachidonic acid in membrane phospholipids. 8-Isoprostaglandin F2α is present in human plasma in two distinct forms - esterified in phospholipids and as the free acid. 8-Isoprostaglandin F2α is a weak TP receptor agonist in vascular smooth muscle.
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- HY-W585890S
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Benzo[pqr]tetraphen-3-ol- 13C6 is 13C labeled Benzo[pqr]tetraphen-3-ol.
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- HY-100043S
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2-Ethyl-3,5-dimethylpyrazine- 13C2 is 13C labeled Nordiphenhydramine (HY-W585858).
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- HY-118560S
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Tricyclodecenyl acetate- 13C2 is 13C labeled 2-Acetylthiazole.
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- HY-150194S
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Fructose-glutamic acid- 13C6 is 13C labeled 2-Ethyl-3,5-dimethylpyrazine,mixtureofisomers.
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- HY-156326S
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(3E,5E)-Octadien-2-one- 13C2 is 13C labeled (3E,5E)-Octadien-2-one.
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- HY-156326S1
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(3E,5Z)-Octadien-2-one- 13C2 is 13C labeled (3E,5Z)-Octadien-2-one.
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- HY-50719S1
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2-Acetyl-1-pyrroline- 13C5 is 13C labeled Fenchone.
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- HY-B1290S3
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2-Phenylethanol- 13C2 is 13C labeled β-Caryophyllene (HY-B1290). β-Caryophyllene is a CB2 receptor agonist.
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- HY-N0368S1
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Linalool- 13C3 is 13C labeled α-Hexylcinnamaldehyde (HY-W014118). α-Hexylcinnamaldehyde, a compound derived from Cinnamaldehyde. α-Hexylcinnamaldehyde has the potential antimutagenic and chemosensitizing properties. α-Hexylcinnamaldehyde is widely used as an ingredient in many personal care, and as an additive in food and the pharmaceutical industry .
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- HY-N0803S1
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Myrcene- 13C3 is 13C labeled trans-2-Decenal (HY-W015551). trans-2-Decenal is an important raw material and intermediate used in organic synthesis, medicine, pesticides and dyes.
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- HY-N10004S
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1-Deoxy-1-L-proline-D-fructose- 13C6 is 13C labeled Jasmine lactone.
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- HY-N7125S
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Cinnamyl acetate- 13C2 is 13C labeled Nerolidol (HY-N1944). Nerolidol has multiple natural membrane activities, possesses anti-cancer, anti-inflammatory, antibacterial and anti-insect activity. Nerolidol Suppresses parasitic activity, suppresses bloodsucking diseases, bloodworm diseases, and other diseases. Nerolidol can protect the cells from lipid and protein properties, damage to DNA, and protect the cells from damage .
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- HY-N9484S
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Menthofuran- 13C2 is 13C labeled Menthol (HY-N1369). Menthol is an analgesic and TRPM8 modulator. TRPM8 is a cold temperature sensing ion channel, and Menthol can regulate TRPM8 to exert analgesic and anti-irritation mechanisms. Menthol stimulates cold receptors and produces a cooling sensation by inhibiting Ca ++ currents in neuronal cell membranes. Menthol also improves oral nicotine rejection in mice .
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- HY-W001942S2
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DL-2-Methylbutyric acid- 13C2 is 13C labeled 1-(Pyridin-2-yl)ethan-1-one.
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- HY-W010392S1
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Ethyl 2-methylbutanoate- 13C2 is 13C labeled Tricyclodecenyl acetate.
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- HY-W010489S1
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2-Phenylacetaldehyde- 13C2 is 13C labeled DL-2-Methylbutyric acid.
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- HY-W012578S1
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2-Isopropyl-3-methoxypyrazine- 13C3 is 13C labeled Octan-2-one.
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- HY-W012932S
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2,4-Dimethylthiazole- 13C3 is 13C labeled 2-Isopropyl-3-methoxypyrazine.
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- HY-W012980S4
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Isovaleric acid- 13C2 is 13C labeled Gamma-decalactone (HY-N7105). Gamma-decalactone, γ-decalactone is used as an essential food additive with a ruity peach flavor . Ricinoleic acid (12-hydroxy-octadec-9-enoic acid) is used as the substrate in most production processes of γ-decalactone .
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- HY-W012998S1
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2,3-Pentanedione- 13C2 is 13C labeled Furaneol (HY-N7093). Furaneol is mainly isolated from American grape (Vitis labrusca) and its hybrid grape. Furaneol is an important aroma compound in fruits and contribute to the strawberry-like note in some wines .
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- HY-W015307S
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4-Ethyloctanoic acid- 13C2 is 13C labeled Cuminaldehyde (HY-Y0790). Cuminaldehyde is the major component of Cuminum cyminum, a natural aldehyde with inhibitory effect on alpha-synuclein fibrillation and cytotoxicity. Cuminaldehyde shows anticancer activity .
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- HY-W015604S
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2,3-Diethyl-5-methylpyrazine- 13C2 is 13C labeled 4-Hydroxy-5-methylfuran-3(2H)-one.
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- HY-W020678S
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2-Methylbutanal- 13C2 is 13C labeled Ethyl 2-methylbutanoate.
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- HY-W102356S1
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Phenethyl acetate- 13C2 is 13C labeled 2-Methylbutanal.
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- HY-W127515S
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trans-2,cis-6-Nonadienal- 13C2 is 13C labeled 4-Ethylphenol (HY-W012836). 4-Ethylphenol is a volatile phenolic compound associated with off-odour in wine.
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- HY-W156840S
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OTNE- 13C3 is 13C labeled 2-methoxy-4-propylphenol.
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- HY-W343292S
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2-Methylbutyl acetate- 13C2 is 13C labeled 3-Mercaptopentan-2-one.
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- HY-W585933S
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Fructose-alanine- 13C6 is 13C labeled Undeca-1,3,5-triene.
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- HY-W585934S
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Fructose-phenylalanine- 13C6 is 13C labeled Undeca-1,3,5-triene.
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- HY-W721295S
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N-(1-Deoxy-D-fructos-1-yl)-L-methionine- 13C6 is 13C labeled 3-Ethyl-5-methyl-2-vinylpyrazine.
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- HY-W738582S
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N-(1-Deoxy-D-fructos-1-yl) -L-threonine- 13C6 is 13C labeled N-(1-Deoxy-D-fructos-1-yl)-L-methionine.
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- HY-W768581
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Acetoin- 13C4 is 13C labeled Acetoin.
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- HY-W772341
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Acetic acid-1- 13C is 13C labeled Acetic acid-1.
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- HY-W779534
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4,5-Dimethyl-3-hydroxy-2(5H)-furanone- 13C2 is 13C labeled 4,5-Dimethyl-3-hydroxy-2(5H)-furanone- 13C2.
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- HY-W779542
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(2E,4E,6E)-2,4,6-Nonatrienal- 13C2 is 13C labeled (2E,4E,6E)-2,4,6-Nonatrienal.
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- HY-W793608S
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N-(1-Deoxy-D-fructos-1-yl)-L-asparagine- 13C6 is 13C labeled Fructose-alanine.
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- HY-Y0045S
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2-Acetylthiazole- 13C2 is 13C labeled Fructose-phenylalanine.
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- HY-W749251
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5-Aminolevulinic acid- 13C2, 15N (5-ALA- 13C2, 15N; δ-Aminolevulinic acid- 13C2, 15N) is 13C- and 15N-labeled 5-Aminolevulinic acid (HY-W000450) .
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- HY-W145482S1
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3-O-Methyl-D-glucopyranose- 13C6 is 13C-labeled 3-O-Methyl-D-glucopyranose (HY-W145482) .
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- HY-W778064
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L-threo-Droxidopa- 13C2, 15N is 13C- and 15N-labeled L-threo-Droxidopa .
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- HY-B0356AS1
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Ciprofloxacin- 13C3, 15N (Bay-09867- 13C3, 15N) monohydrochloride is 13C- and 15N-labeled Ciprofloxacin (monohydrochloride) (HY-B0356A) .
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- HY-W779017
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Thymidine- 13C5 (DThyd- 13C5; NSC 21548- 13C5) is 13C-labeled Thymidine (HY-N1150) .
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- HY-B0283S1
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Acipimox- 13C2, 15N2 (K-9321- 13C2, 15N2) is 13C- and 15N-labeled Acipimox (HY-B0283) .
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- HY-B0084S3
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Dienogest- 13C2, 15N (STS 557- 13C2, 15N) is 13C- and 15N-labeled Dienogest (HY-B0084) .
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- HY-W777418
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Isosorbide mononitrate- 13C6 (Isosorbide-5-mononitrate- 13C6) is 13C-labeled Isosorbide mononitrate (HY-B0642) .
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- HY-B0122SS1
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Topiramate- 13C6-1 (McN 4853- 13C6-1; RWJ 17021- 13C6-1) is 13C-labeled Topiramate (HY-B0122) .
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- HY-W018386S1
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3-Bromo-L-tyrosine- 13C9 (3-Bromo-Tyr- 13C9) is 13C-labeled 3-?Bromo-?L-?tyrosine (HY-W018386) .
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- HY-116021S
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Buquinolate-13C3 is the 13C3 labeled Buquinolate. Buquinolate is a quinoline derivative, which is developed as a coccidiostat for the prevention of coccidiosis in poultry .
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- HY-114360AS1
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Taurohyodeoxycholic acid-d4 (sodium) is a deuterated labeled Taurohyodeoxycholic acid (sodium) . Taurohyodeoxycholic acid (THDCA) sodium is the taurine-conjugated form of the secondary bile acid hyodeoxycholic acid. Taurohyodeoxycholic acid can also reduce the activity and expression of myeloperoxidase TNF-α and IL-6, as well as colonic damage in TNBS-induced ulcerative colitis mouse model.
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- HY-141629S1
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N-Palmitoyl-D-sphingomyelin-13C is a deuterated labeled N-Palmitoyl-D-sphingomyelin . N-Palmitoyl-D-sphingomyelin (Sphingomyelin 16:0) (Compound SM-03) can be used for the synthesis of lipid nanoparticles .
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- HY-109506S9
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DPPC-13C2 is a deuterated labeled DPPC . DPPC (129Y83) is a phosphoglyceride that can be used to prepare lipid monolayers, bilayers, and liposomes. DPPC is the main lipid component of pulmonary surfactant. Dppc-liposome can be effectively used as a delivery vector to induce an immune response against GSL antigen in mice .
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- HY-16637S5
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Folic acid-13C6 is a deuterated labeled Folic acid . Folic acid (Vitamin B9) is a orally active essential nutrient from the B complex group of vitamins. Folic acid shows antidepressant-like effect. Folic acid sodium reduces the risk of neonatal neural tube defects. Folic acid can be used to the research of megaloblastic and macrocytic anemias due to folic deficiency .
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- HY-131622S
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7-Aminoclonazepam-13C6 is a deuterated labeled 7-Aminoclonazepam .
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- HY-B1804S
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Tricaprilin-13C3 is a deuterated labeled Tricaprilin . Tricaprilin (Trioctanoin) is used in study for patients with mild to moderate Alzheimer's disease and has a role as an anticonvulsant and a plant metabolite .
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- HY-151997S
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1,2-Dioleoyl-3-lauroyl-rac-glycerol- 13C3 is the 13C-labeled 1,2-Dioleoyl-3-lauroyl-rac-glycerol (HY-165089), 1,2-Dioleoyl-3-lauroyl-rac-glycerol (1,2-Olein-3-laurin) is a triglyceride identified by specific analytical methods in human milk, infant formula, other mammalian milk, and vegetable oils, with specific structural and distribution characteristics.
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- HY-W814363
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Octadec-9-enoic acid-13C5 is a deuterated labeled Octadec-9-enoic acid-13C5 .
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- HY-W585905
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Trimethylammonium chloride-13C3 is a deuterated labeled Trimethylammonium chloride-13C3 .
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- HY-W009326S
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Laurocapram-15N is a deuterated labeled Laurocapram . Laurocapram is a absorption enhancer and has been one of the most effective for substances of both lipophilic and hydrophilic nature .
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- HY-76082S1
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L-Pyroglutamic acid-13C5 is a deuterated labeled L-Pyroglutamic acid . L-Pyroglutamic acid is the levo-isomer of Pyroglutamic acid. L-Pyroglutamic acid is the biologically active enantiomer in humans. Pyroglutamic acid is an intermediate in glutathione metabolism.
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- HY-W654190
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Fipronil sulfone-13C2,15N2 is a deuterated labeled Fipronil sulfone-13C2,15N2 .
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- HY-W654241
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Isopentenyl pyrophosphate-13C2 is a deuterated labeled Isopentenyl pyrophosphate-13C2 .
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- HY-66008S2
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N-Acetyl mesalazine-13C6 is a deuterated labeled N-Acetyl mesalazine . N-Acetyl mesalazine (N-Acetyl-5-aminosalicylic acid) is the metabolite of 5-Aminosalicylic Acid (HY-15027) with endoscopic activity. N-Acetyl mesalazine can be used for the research of ulcerative colitis .
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- HY-W782153
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Acetophenone-13C6 is a deuterated labeled Acetophenone-13C6 .
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- HY-10260S2
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Vandetanib-13C6 is a deuterated labeled Vandetanib . Vandetanib (D6474) is a potent, orally active inhibitor of VEGFR2/KDR tyrosine kinase activity (IC50=40 nM). Vandetanib also has activity versus the tyrosine kinase activity of VEGFR3/FLT4 (IC50=110 nM) and EGFR/HER1 (IC50=500 nM) .
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- HY-137222S
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4',5-Dihydroxy Diclofenac-13C6 is a deuterated derivative of Diclofenac (HY-15036). Diclofenac is a potent COX inhibitor with anti-inflammatory activity .
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- HY-W777526
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Nitisinone-13C6 is a deuterated labeled Nitisinone-13C6 .
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- HY-W780150
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1-Bromobenzene-13C6 is a deuterated labeled 1-Bromobenzene-13C6 .
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- HY-W013186S1
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Lansoprazole sulfide- 13C6 is a deuterated labeled Lansoprazole sulfide .
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- HY-B0284S2
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Nifedipine-13C8 is a deuterated labeled Nifedipine . Nifedipine (BAY-a-1040) is a potent calcium channel blocker and agent of choice for cardiac insufficiencies.
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- HY-W777286
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rac Lenalidomide-13C5 is a deuterated labeled rac Lenalidomide-13C5 .
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- HY-15284S3
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Prasugrel-13C6 is a deuterated labeled Prasugrel . Prasugrel (PCR 4099), a thienopyridine and proagent, inhibits platelet function. Prasugrel is an orally active and potent P2Y12 receptor antagonist, and inhibits ADP-induced platelet aggregation .
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- HY-W013636S4
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2-Ketoglutaric acid-13C2 is a deuterated labeled 2-Ketoglutaric acid . 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC50=15 mM) .
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- HY-17356S2
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Fenofibrate-13C6 is a deuterated labeled Fenofibrate . Fenofibrate is a selective PPARα agonist with an EC50 of 30 μM. Fenofibrate also inhibits human cytochrome P450 isoforms, with IC50s of 0.2, 0.7, 9.7, 4.8 and 142.1 μM for CYP2C19, CYP2B6, CYP2C9, CYP2C8, and CYP3A4, respectively.
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- HY-113128S
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sn-Glycerol 3-phosphate- 13C3 disodium is the 13C-labeled sn-Glycerol 3-phosphate disodium. sn-Glycerol 3-phosphate disodium is produced by cytosolic glycerol 3-phosphate dehydrogenase pathway through the reduction of dihydroxyacetone phosphate using NADH formed during glycolysis .
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- HY-115705
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1,2,3-Tri-10(Z)-heptadecenoyl glycerol (TG(17:1/17:1/17:1)) is a biochemical assay reagent, which can be used as an internal standard for the quantification of biological triglyceride .
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- HY-W705777
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2-Chloropropane-1,3-diyl dioleate (1,1′-(2-Chloro-1,3-propanediyl) di-(9Z)-9-octadecenoate) is an ester product.
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- HY-B1252AS
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Cefalonium-d4 (hydrate) is the deuterium labeled Cefalonium (hydrate)(HY-B1252A).Cefalonium hydrate is the first-generation β-lactam cephalosporin antibiotic that is widely used to research bovine mastitis caused by Gram-positive bacteria including staphylococci .
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- HY-B0152S7
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Adenine-15N5 hydrochloride hydrate (6-Aminopurine-15N5 hydrochloride hydrate) is the deuterium labeled Adenine (HY-B0152). Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis .
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- HY-15121S1
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L-Theanine-13C2,15N2yes 13C2, 15N2Tagged L-Theanine (HY-15121).
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- HY-152903S
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Sulfuric-34S acid disodium is an active compound.
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- HY-118645S1
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1'-Hydroxymidazolam- 13C3 is the 13C labeled 1'-Hydroxymidazolam[1].
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- HY-13771S1
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Ursodeoxycholic acid- 13C is the 13C labeled Ursodeoxycholic acid. Ursodeoxycholic acid (Ursodeoxycholate) is a secondary bile acid issued from the transformation of (cheno)deoxycholic acid by intestinal bacteria, acting as a key regulator of the intestinal barrier integrity and essential for lipid metabolism. Ursodeoxycholic acid acts as signaling molecule, exerting its effects by interacting with bile acid activated receptors, including G-protein coupled bile acid receptor 5 (TGR5, GPCR19) and the farnesoid X receptor (FXR). Ursodeoxycholic acid can be used for the research of a variety of hepatic and gastrointestinal diseases. Orally active[1][2].
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- HY-W779002
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alpha-D-glucose-13C2-1 is a 13C labeled alpha-D-glucose. alpha-D-glucose is an endogenous metabolite[1].
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- HY-112537S2
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D-Glucose 6-phosphate-13C is 13C labeled D-Glucose 6-phosphate (HY-112537). D-Glucose 6-phosphate is glucose phosphorylated with a hydroxyl group on carbon 6 .
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- HY-W750551
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Glyphosate-13C,15N is 13C and 15N labeled Glyphosate (HY-B0863).
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- HY-79128S1
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Fmoc-L-Lys (Boc)-OH- 13C6, 15N2 is a 15N-labeled and 13C-labled Triclabendazole.
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- HY-W777649
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Oxypurinol- 13C, 15N2-1 (Oxipurinol- 13C, 15N2-1) is 15N and 13C labeled Oxypurinol (HY-19657). Oxipurinol, the major active metabolite of Allopurinoll (HY-B0219), is an inhibitor of xanthine oxidase. Oxipurinol can be used to regulate blood urate levels and treat gout .
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- HY-W715351S
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1,2,4,5,7,8-Hexachloro naphthalene- 13C10 is 13C labeled 1,2,4,5,7,8-Hexachloronaphthalene .
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- HY-W549233S
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Tris(4-chlorophenyl)methane- 13C19 is 13C labeled Tris(4-chlorophenyl)methane .
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- HY-W748196S
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1,2,3,4,6,7-Hexachloro dibenzo-p-dioxin- 13C12 is 13C labeled 1, 2, 3, 4, 6, 7- Hexachlorodibenzo- p- dioxin .
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- HY-W715365S
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1,2,3-Tribromo-5-(3,4-dibromophenoxy)benzene- 13C12 is 13C labeled 1,2,3-Tribromo-5-(3,4-dibromophenoxy)benzene .
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- HY-127035S1
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Tristearin- 13C3 (Glycerol tristearate- 13C3) is 13C labeled Tristearin. Tristearin is a triglyceride derived from three units of stearic acid .
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- HY-W748346
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2,2′,3,3′,5,5′,6-Heptachloro biphenyl- 13C12 is 13C labeled 2,2',3,3',5,5',6-Heptachloro-1,1'-biphenyl .
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- HY-23805S
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3,6-Dichloro-9H-carbazole- 13C12 is 13C labeled 3,6-Dichloro-9H-carbazole .
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- HY-W327895S
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Tris(4-chlorophenyl)methanol- 13C19 is 13C labeled Tris(4-chlorophenyl)methanol .
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- HY-130462S2
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1-Palmitoyl-2-oleoyl-sn-glycero-3-PC- 13C16 (POPC- 13C16) is 13C labeled 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (POPC), a phospholipid, is a major component of biological membranes. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC is used for the preparation of liposomes and studying the properties of lipid bilayers .
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- HY-W718525S
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2,3′,4′,5-Tetrachloro biphenyl- 13C12 is 13C labeled 2,3',4',5-Tetrachloro-1,1'-biphenyl .
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- HY-W751145
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Diphenyl ether- 13C12 is 13C labeled Diphenyl ether. Oxydibenzene is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
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- HY-W750297
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p,p'-DDD- 13C12 is 13C labeled p,p'-DDD. p,p'-DDD is a major metabolite of p,p'-DDT. p,p'-DDD occurs in the feces and livers of rats, that are given p,p'-DDT by stomach tube, but not of rats injected intraperitoneally with p,p'-DDT .
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- HY-W749374
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1,2-Bis(2,4,6-tribromophenoxy)ethane- 13C12 is 13C labeled 1,1-(1,2-Ethanediylbis(oxy))bis(2,4,6-tribromobenzene) .
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- HY-W716411S
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1,2,3,4,5-Pentabromo-6-(2,3-dibromophenoxy)benzene- 13C12 is 13C labeled 1,2,3,4,5-Pentabromo-6-(2,3-dibromophenoxy)benzene .
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- HY-W748312
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1, 2, 3, 4, 7, 8, 9-Heptachloro-dibenzofuran- 13C12 is 13C labeled 1,2,3,4,7,8,9-Heptachlorodibenzo[b,d]furan .
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- HY-W748319
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K 101- 13C12 is 13C labeled K 101 .
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- HY-W748320
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2,2',3,3',4,5,5',6,6'-Nonachloro-1,1'-biphenyl- 13C12 is 13C labeled 2,2',3,3',4,5,5',6,6'-Nonachloro-1,1'-biphenyl .
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- HY-W748321
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2,2',3,4',5,6,6'-heptachloro-1,1'-biphenyl- 13C12 is 13C labeled 2,2',3,4',5,6,6'-Heptachloro-1,1'-biphenyl .
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- HY-W748322
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1, 2, 3, 4, 7, 8- Hexachloro-dibenzofuran- 13C12 is 13C labeled 1,2,3,4,7,8-Hexachlorodibenzofuran .
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- HY-165124S
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1,2,3,4,6,7,8-Heptachlorodibenz- 13C12 is 13C labeled 1,2,3,4,6,7,8-Heptachlorodibenz. 1,2,3,4,6,7,8-Heptachlorodibenz 是一种生化试剂。 .
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- HY-W748327
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2,5-Dichloro-1,1'-biphenyl- 13C12 is 13C labeled 2,5-Dichloro-1,1'-biphenyl .
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- HY-W748343
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2,2',5,5'-Tetrachloro-1,1'-biphenyl- 13C12 is 13C labeled 2,2',5,5'-Tetrachloro-1,1'-biphenyl .
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- HY-W748345
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2,3',4,4',5,5'-Hexachloro-1,1'-biphenyl- 13C12 is 13C labeled 2,3',4,4',5,5'-Hexachloro-1,1'-biphenyl .
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- HY-W748350
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2,2',3,3',4,4',5,5',6-Nonachloro-1,1'-biphenyl- 13C12 is 13C labeled 2,2',3,3',4,4',5,5',6-Nonachloro-1,1'-biphenyl .
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- HY-W715357S
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3,3′,4,4′-Tetrabromo diphenyl ether- 13C12 is 13C labeled 4,4'-Oxybis(1,2-dibromobenzene) .
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- HY-166906S
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cis-Nonachlor- 13C10 is 13C labeled (1R,2S,3S,3aR,4R,7R,7aS)-1,2,3,4,5,6,7,8,8-Nonachloro-2,3,3a,4,7,7a-hexahydro-1H-4,7-methanoindene .
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- HY-W748290
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3,4,4',5-Tetrachloro-1,1'-biphenyl- 13C12 is 13C labeled 3,4,4',5-Tetrachloro-1,1'-biphenyl .
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- HY-W748204
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1,2,3,7,8-Pentachloro dibenzo-p-dioxin- 13C12 is 13C labeled 1,2,3,7,8-Pentachlorodibenzo-p-dioxin. 1,2,3,7,8-Pentachlorodibenzo-p-dioxin is a biochemical reagent .
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- HY-W747639
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Glycidyl Stearate- 13C3 is 13C labeled Glycidyl stearate. Oxiran-2-ylmethyl stearate is a compound belonging to the class of esters. It contains reactive oxirane or epoxy groups that give the molecule its unique properties. Oxiran-2-ylmethyl stearate is derived from stearic acid and epichlorohydrin, which are naturally occurring substances. Glycidyl stearate is commonly used in various industrial applications such as the production of coatings, adhesives and surfactants. It can also be used as a crosslinking agent in the manufacture of polymers and resins .
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- HY-W747491
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Triclosan- 13C12 is 13C labeled Triclosan. Triclosan is a broad-spectrum antibacterial agent that inhibits bacterial fatty acid synthesis at the enoyl-acyl carrier protein reductase (FabI) step. Triclosan inhibits E. coli enoyl-acyl carrier protein reductase (FabI) and FabI containing a glycine-to-valine substitution at position 93 (FabIG93V) with IC50s of 2 μM and 10 μM, respectively. Triclosan causes apoptotic effect in cultured rat neural stem cells (NSC). Triclosan exacerbates colitis and colitis-associated colorectal tumorigenesis in animal models .
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- HY-W762019S
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1,2,3,4,7,8-Hexachloro dibenzo-p-dioxin- 13C12 (1,2,3,4,7,8-HxCDD- 13C12) is 13C labeled 1,2,3,4,7,8-Hexachlorodibenzo-p-dioxin .
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- HY-13690S3
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Mitotane- 13C12 (2,4′-DDD- 13C12) is 13C labeled Mitotane. Mitotane (2,4′-DDD), an isomer of DDD and derivative of dichlorodiphenyltrichloroethane (DDT), is an antineoplastic agent, can be used to research adrenocortical carcinoma. Mitotane exert its adrenocorticolytic effect at least in part through lipotoxicity induced by intracellular free cholesterol (FC) accumulation. Mitotane can have direct pituitary effects on corticotroph cells. Mitotane can induce CYP3A4 gene expression via steroid and xenobiotic receptor (SXR) activation, and has agent-agent interactions .
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- HY-W140740S
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Hexabromobenzene- 13C6 (Perbromobenzene- 13C6) is 13C labeled Hexabromobenzene .
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- HY-W715180S
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2,3-Dibromo-7,8-dichloro dibenzo-p-dioxin- 13C12 is 13C labeled 2,3-Dibromo-7,8-dichlorodibenzo[b,E][1,4]dioxine .
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- HY-W715187S
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3-Bromo-2,7,8-trichloro dibenzofuran- 13C12 is 13C labeled 3-Bromo-2,7,8-trichlorodibenzo[b,d]furan .
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- HY-109590S3
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Arachidonic acid- 13C4 (Immunocytophyt- 13C4) is 13C labeled Arachidonic acid. Arachidonic acid (Immunocytophyt) is a polyunsaturated omega-6 fatty acid and a major constituent of biomembranes. Arachidonic acid also acts as the substrate for various lipid mediators, such as prostaglandins (PGs). Arachidonic acid improves cognitive response and cardiovascular function .
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- HY-W011297S2
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Methyl arachidonate- 13C4 (Arachidonic acid methyl ester- 13C4) is 13C labeled Methyl arachidonate. Methyl arachidonate (Arachidonic acid methyl ester) is a fatty acid methyl ester resulting from the formal condensation of the carboxy group of arachidonic acid with methanol. Methyl arachidonate has activity of human blood serum metabolite .
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- HY-W653853
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Ritonavir- 13C3 is 13C labeled Ritonavir. Ritonavir (ABT 538) is an inhibitor of HIV protease used to treat HIV infection and AIDS. Ritonavir is also a SARS-CoV 3CL pro inhibitor with an IC50 of 1.61 μM .
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- HY-W653916
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8-Hydroxy-2'-deoxyguanosine- 13C, 15N2 is 13C and 15N labeled 8-Hydroxy-2'-deoxyguanosine. 8-Hydroxy-2'-deoxyguanosine is a critical biomarker of oxidative stress and carcinogenesis .
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- HY-W653970
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5-Azacytidine- 15N4 is 13C and 15N labeled 5-Azacytidine. 5-Azacytidine (Azacitidine; 5-AzaC; Ladakamycin) is a nucleoside analogue of cytidine that specifically inhibits DNA methylation. 5-Azacytidine is incorporated into DNA to covalently trap DNA methyltransferases and contributes to reverse epigenetic changes. 5-Azacytidine induces cell autophagy .
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- HY-W654000
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Cyclic GMP- 13C, 15N2 is 13C and 15N labeled Cyclic GMP. Cyclic GMP (cGAMP) is an endogenous second messenger that triggers interferon production in response to cytoplasmic DNA. Cyclic GMP activates the stimulator of interferon genes (STING), activating a signaling cascade that leads to the production of type I interferons and other immune mediators .
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- HY-W654002
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(3R)-3-Hydroxybutyric acid-1- 13C is 13C labeled (R)-3-Hydroxybutanoic acid. (R)-3-Hydroxybutanoic acid is a metabolite, and converted from acetoacetic acid catalyzed by 3-hydroxybutyrate dehydrogenase. (R)-3-Hydroxybutanoic acid has applications as a nutrition source and as a precursor for vitamins, antibiotics and pheromones .
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- HY-W654004
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8-Hydroxy guanosine- 13C, 15N2 is 13C and 15N labeled 8-Hydroxyguanosine. 8-Hydroxyguanosine, an oxidized nucleoside, is a marker of RNA oxidative damage and oxidative stress. 8-Hydroxyguanosine stimulates proliferation and differentiation of B cells .
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- HY-W654080
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Bisphenol P- 13C4 is 13C labeled α,α'-Bis(4-hydroxyphenyl)-1,4-diisopropylbenzene .
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- HY-W654082
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Bisphenol e- 13C6 is 13C labeled Bisphenol E. Bisphenol E (4,4'-Ethylidenediphenol) is a biochemical reagent .
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- HY-W654098
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Cefazolin- 13C2, 15N (sodium) is 13C and 15N labeled Cefazolin (sodium). Cefazolin sodium is a first-generation cephalosporin antibiotic and can be used in varieties of bacterial infections research . Cefazolin sodium has anti-inflammatory effect and can attenuate post-operative cognitive dysfunction (POCD).
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- HY-W654127
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Cytarabine- 13C3 5'-monophosphate is 13C labeled Cytarabine 5’-monophosphate .
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- HY-W654136
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2'-Deoxycytidine-2'- 13C is 13C labeled 2'-Deoxycytidine. 2'-Deoxycytidine, a deoxyribonucleoside, can inhibit biological effects of Bromodeoxyuridine (Brdu). 2'-Deoxycytidine is essential for the synthesis of nucleic acids, that can be used for the research of cancer .
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- HY-W654156
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Diclazuril- 13C3, 15N 2 is 13C and 15N labeled Diclazuril. Diclazuril (R-64433), a benzeneacetonitrile derivative, is a potent and orally active anticoccidial agent. Diclazuril can be used for the research of certain infectious and parasitic diseases, including coccidiosis, acute toxoplasmosis, equine protozoal pyoencephalitis (EPM) et.al .
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- HY-W654191
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Fipronil detrifluoromethylsulfinyl- 13C2, 15N2 is 13C and 15N labeled 5-Amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-1H-pyrazole-3-carbonitrile .
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- HY-W617979S
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3,4-Dichlorodiphenyl ether- 13C12 is 13C labeled 1,2-Dichloro-4-phenoxybenzene .
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- HY-W777702
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2,2',3,4',5,5',6-Heptachloro-4-biphenylol- 13C12 is 13C labeled 2,2',3,4',5,5',6-Heptachloro-[1,1'-biphenyl]-4-ol .
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- HY-W552229S
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2,8-Dichloro dibenzo-p-dioxin- 13C12 is 13C labeled 2,8-Dichlorodibenzo[b,e][1,4]dioxine .
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- HY-W517076S
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1,2,3,6,7,8-Hexachloro dibenzo-p-dioxin- 13C12 is 13C labeled 1,2,3,6,7,8-Hexachlorodibenzo[b,e][1,4]dioxine .
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- HY-W017086S2
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Dibenzo[b,d]furan- 13C12 is 13C labeled Dibenzo[b,d]furan. Dibenzo[b,d]furan is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
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- HY-166917S
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1,3,6,8-Tetrachloro-dibenzofuran- 13C12 is 13C labeled 1,3,6,8-Tetrachlorodibenzofuran .
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- HY-W710384S
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1,2,3,4,5,6,7-Heptachloro naphthalene- 13C10 is 13C labeled 1,2,3,4,5,6,7-Heptachloronaphthalene .
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- HY-166896S
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2,3,3',4',5,5'-Hexachloro-1,1'-biphenyl- 13C12 is 13C labeled 2,3,3',4',5,5'-Hexachloro-1,1'-biphenyl .
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- HY-W714574S
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2,2′,3,3′,4,4′,5-Heptachloro biphenyl- 13C12 is 13C labeled 2,2',3,3',4,4',5-Heptachloro-1,1'-biphenyl .
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- HY-W774917S
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trans Chlordane- 13C10 is 13C labeled trans-Chlordane .
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- HY-166898S
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trans Nonachlor- 13C10 is 13C labeled (1R,2R,3S,3aR,4R,7R,7aS)-1,2,3,4,5,6,7,8,8-Nonachloro-2,3,3a,4,7,7a-hexahydro-1H-4,7-methanoindene .
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- HY-W718588S
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2,2',3,3',5,5'-Hexachlorobiphenyl- 13C12 is 13C labeled 2,2',3,3',5,5'-Hexachloro-1,1'-biphenyl .
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- HY-W152813S
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3',4'-Dichloro-4-biphenylol- 13C12 is 13C labeled 4-(3,4-Dichlorophenyl)phenol .
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- HY-166908S
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2,2',3,3',4,4',5,6,6'-Nonabromo diphenyl ether- 13C12 is 13C labeled 1,2,3,4,5-Pentabromo-6-(2,3,4,6-tetrabromophenoxy)benzene .
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- HY-W092778S
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4,4′-Dibromo diphenyl ether- 13C12 is 13C labeled 4,4'-Oxybis(bromobenzene) .
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- HY-W013061S11
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Tripalmitin (Glycerol 13C3, 13C 99%) is 13C labeled Propane-1,2,3-triyl tripalmitate. Propane-1,2,3-triyl tripalmitate is an endogenous metabolite .
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- HY-W715121S
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2,3,7,8-Tetrabromo dibenzo-p-dioxin- 13C12 is 13C labeled 2,3,7,8-Tetrabromodibenzo[b,E][1,4]dioxine .
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- HY-W718518S
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2,3,4,4′-Tetrachloro biphenyl- 13C12 is 13C labeled 2,3,4,4'-Tetrachloro-1,1'-biphenyl .
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- HY-W718532S
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3,3′,4,5′-Tetrachloro biphenyl- 13C12 is 13C labeled 3,3',4,5'-Tetrachloro-1,1'-biphenyl .
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- HY-166928S
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1,3,6,8-Tetrachloro-9H-carbazole- 13C12 is 13C labeled 1,3,6,8-Tetrachloro-9H-carbazole .
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- HY-W715184S
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8-Bromo-2,3-dichlorodibenzofuran- 13C12 is 13C labeled 8-Bromo-2,3-dichlorodibenzo[b,d]furan .
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- HY-W708160S
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1,2,3-Tribromo-4-(2,4,5-tribromophenoxy)benzene- 13C12 is 13C labeled 1,2,3-Tribromo-4-(2,4,5-tribromophenoxy)benzene .
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- HY-76595S1
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4-Bromo diphenyl ether- 13C12 is 13C labeled 1-Bromo-4-phenoxybenzene .
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- HY-W715361S
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2,4,6,8-Tetrachloro dibenzothiophene- 13C12 is 13C labeled 2,4,6,8-Tetrachlorodibenzo[b,d]thiophene .
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- HY-W354105S
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3,3',4,5,5'-Pentachloro biphenyl- 13C12 is 13C labeled 3,3',4,5,5'-Pentachloro-1,1'-biphenyl .
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- HY-W718472S
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3,3′-Dichloro biphenyl- 13C12 is 13C labeled 3,3'-Dichloro-1,1'-biphenyl .
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- HY-W673588S
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2,3-Dichlorobiphenyl- 13C12 is 13C labeled 1,1'-Biphenyl, 2,3-Dichloro- .
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- HY-W715198S
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4-Bromo-2,3,7,8-tetrachlorodibenzofuran- 13C12 is 13C labeled 4-Bromo-2,3,7,8-tetrachlorodibenzo[b,d]furan .
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- HY-B1805S1
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Triclocarban- 13C13 (3,4,4'-Trichlorocarbanilide- 13C13) is 13C labeled Triclocarban. Triclocarban (3,4,4′-Trichlorocarbanilide), a broad spectrum antibacterial compound, is widely used in a broad range of applications such as the production of soaps, skin creams, toothpastes and deodorants. Triclocarban is a potential endocrine-disrupting chemical with the capacity to modulate androgen and estrogen activities as well as other hormone-mediated biological processes .
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- HY-W718614S
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2,3,3′,4,5,5′-Hexachloro biphenyl- 13C12 is 13C labeled 2,3,3',4,5,5'-Hexachloro-1,1'-biphenyl .
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- HY-W715199S
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Pentabromo benzene- 13C6 is 13C labeled 1,2,3,4,5-Pentabromobenzene .
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- HY-W703429S
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2,3,6,7-Tetrachloro-naphthalene- 13C10 is 13C labeled 2,3,6,7-Tetrachloronaphthalene .
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- HY-W715311S
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2,2',3,3',4',5,5'-Heptachloro-4-biphenylol- 13C12 is 13C labeled 2,2',3,3',4',5,5'-Heptachloro-[1,1'-biphenyl]-4-ol .
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- HY-166956S
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Chlordene- 13C10 is 13C labeled 1,7,8,9,10,10-Hexachlorotricyclo[5.2.1.0,2,6]deca-3,8-diene .
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- HY-W587423S
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2,2′,3,3′,4,4′,5,5′,6-Nonabromo diphenyl ether- 13C12 is 13C labeled 2,2′,3,3′,4,4′,5,5′,6-Nonabromodiphenyl ether .
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- HY-W094748S1
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Dibenzo-p-dioxin- 13C12 is 13C labeled Dibenzo[b,e][1,4]dioxin .
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- HY-W013058S
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1,2-Bis(pentabromophenyl)ethane- 13C14 is 13C labeled 1,2-Bis(perbromophenyl)ethane .
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- HY-150012S1
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N-Lactoyl-Phenylalanine- 13C6 (Lac-Phe- 13C6) is 13C labeled N-Lactoyl-Phenylalanine. N-Lactoyl-Phenylalanine is a blood-derived signaling metabolite that can be induced by exercise. N-Lactoyl-Phenylalanine can reduce obesity and improve glucose tolerance .
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- HY-W779015
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5-Methyluridine- 13C5 is 13C labeled 5-Methyluridine .
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- HY-119649S
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Flonicamid- 15N,18O (IKI220- 15N,18O) is 15N labeled Flonicamid. Flonicamid (IKI220) is a novel systemic insecticide with selective activity against hemipterous pests. The main insecticidal mechanism of flonicamid is starvation based on the inhibition of stylet penetration to plant tissues .
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- HY-165696S1
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2,4-Dicarbamoyl-3,5,6-trichlorobenzenesulfonate (sodium)- 15N2 is 15N labeled 2,4-Dicarbamoyl-3,5,6-trichlorobenzenesulfonate (sodium) .
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- HY-166963S
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3,4,4′-Trichloro diphenyl ether- 13C12 is 13C labeled 3,4,4′-Trichloro diphenyl ether .
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- HY-152040S
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Tenuazonic acid-(acetyl- 13C2) (mixture of diastereomers) in methanol (3-(Acetyl- 13C2)-5-((S)-sec-butyl)-4-hydroxy-1,5-dihydro-2H-pyrrol-2-one) is 13C labeled Tenuazonic acid-(acetyl) (mixture of diastereomers) in methanol .
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- HY-W018386AS
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3- Bromo- L- tyrosine- 13C9, 15N (3-Bromo-Tyr- 13C9, 15N) TFAis 13C and 15N labeled 3- Bromo- L- tyrosine (TFA). 3-Bromo-L-tyrosine (3-Bromo-Tyr) TFA is a tyrosine derivative .
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- HY-166957S
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1,2,3,7,8-Pentachloro naphthalene- 13C10 is 13C labeled 1,2,3,7,8-Pentachloro naphthalene .
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- HY-W654373S
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4-((Hydrazinyl)methyl)benzene-1,2,3-triol- 15N2 (oxalate) is 15N labeled 2,3,4-Trihydroxybenzylhydrazine Oxalic Acid Salt .
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- HY-165686
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Benalaxyl metabolite M2- 13C3 (N-(Carboxyacetyl)-N-(2,6-dimethylphenyl)-DL-alanine- 13C3) is 13C labeled Benalaxyl metabolite M2 .
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- HY-166934S
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Endosulfan- 13C9 (sulfate) is 13C labeled Endosulfan (sulfate) .
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- HY-W779193
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2-Amino-3-methyl-3H-imidazo[4,5-f]quinoline-2- 13C is 13C labeled 2-Ammo-3-memyl-imidazo-[4,5-f]-quinoIine. 2-Ammo-3-memyl-imidazo-[4,5-f]-quinoIine is a mutagenic compound .
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- HY-165694S
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2-Carbamoyl-3,5,6-trichloro-4-cyanobenzenesulfonate (sodium)- 13C2, 15N2 is 13C and 15N labeled 2-Carbamoyl-3,5,6-trichloro-4-cyanobenzenesulfonate (sodium) .
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- HY-W728206S
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Chlorothalonil Metabolite SYN507900- 15N2 is 15N labeled 2,3,6-Trichloro-5-cyano-4-hydroxybenzamide .
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- HY-165696S
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2,4-Dicarbamoyl-3,5,6-trichlorobenzenesulfonate (sodium)- 13C2, 15N2 is 13C and 15N labeled 2,4-Dicarbamoyl-3,5,6-trichlorobenzenesulfonate (sodium) .
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- HY-13966S3
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2-Deoxy-D-glucose- 13C6 (2-DG- 13C6) is 13C labeled 2-Deoxy-D-glucose. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase .
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- HY-110382S
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13C20, 15N10-Cyclic di-GMP ( 13C20, 15N10-c-di-GMP) is 13C and 15N labeled Cyclic-di-GMP (disodium). Cyclic-di-GMP disodium is a STING agonist and a bacterial second messenger that coordinates different aspects of bacterial growth and behavior, including motility, virulence, biofilm formation, and cell cycle progression. Cyclic-di-GMP disodium has anti-cancer cell proliferation activity and also induces elevated CD4 receptor expression and cell cycle arrest. Cyclic-di-GMP disodium can be used in cancer research .
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- HY-W748354
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2,2',4,4',6,6'-Hexachloro-1,1'-biphenyl- 13C12 (2,2',4,4',6,6'-Hexachlorobiphenyl- 13C12) is 13C labeled 2,2',4,4',6,6'-Hexachloro-1,1'-biphenyl .
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- HY-W748355
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2,2',3,3',5,5',6,6'-Octachloro-1,1'-biphenyl- 13C12 is 13C labeled 2,2',3,3',5,5',6,6'-Octachloro-1,1'-biphenyl .
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- HY-W778058
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Guanosine- 13C, 15N2 (DL-Guanosine- 13C, 15N2) is 13C and 15N labeled Guanosine .
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-
- HY-W777335
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Zanamivir- 13C, 15N2 is 13C and 15N labeled Zanamivir .
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-
- HY-W777964
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Phloroglucinol- 13C6 is 13C labeled Phloroglucinol .
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- HY-166894S
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3,3′,4,4′,5,5′-Hexabromo diphenyl ether- 13C12 is 13C labeled 3,3′,4,4′,5,5′-Hexabromo diphenyl ether .
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- HY-W778391
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Bisphenol A- 13C2 is 13C labeled Bisphenol A. Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders .
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- HY-W778393
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cis-Tranexamic acid- 13C2, 15N is 13C and 15N labeled cis-Tranexamic acid .
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- HY-14879S2
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Avibactam sodium salt- 13C5 (NXL-104- 13C5) is 13C labeled Avibactam (sodium). Avibactam sodium (NXL-104) is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactamase TEM-1 and CTX-M-15 with IC50s of 8 nM and 5 nM, respectively .
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- HY-166959S
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2,3,8-Trichloro dibenzofuran- 13C12 is 13C labeled 2,3,8-Trichloro dibenzofuran .
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- HY-166931S
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2,2',4,4'-Tetrabromo-6-methoxy-diphenyl ether- 13C12 is 13C labeled 2,2',4,4'-Tetrabromo-6-methoxy-diphenyl ether .
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-
- HY-166909S
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1,4,5-Trichloronaphthalene- 13C10 is 13C labeled 1,4,5-Trichloronaphthalene .
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- HY-B0136S
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Cefdinir- 13C, 15N2 (FK-482- 13C, 15N2) is 13C and 15N labeled Cefdinir. Cefdinir (FK-482) is a semi-synthetic, broad-spectrum antibiotic in the third generation of the cephalosporin class, which is proved to be effective for infections caused by several Gram-negative and Gram-positive bacteria. Cefdinir can be used for the research of common bacterial infections of the ear, sinus, throat, and skin .
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- HY-W719722
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Chloraminophenamide- 15N2 is 15N labeled Chloraminophenamide .
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-
- HY-W700491
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AalphaC- 15N3 (2-Amino-α-carboline- 15N3) is 15N labeled AalphaC. AalphaC (AαC) is a potential carcinogen with carcinogenic activity. AalphaC is an important biomarker in tobacco smoke and is associated with tobacco smoke exposure. Urinary concentrations of AalphaC are significantly higher in dedicated smokers than in non-smokers, indicating its importance in monitoring tobacco exposure. AalphaC levels increase significantly with increasing serum nicotine levels, indicating its close relationship with tobacco use. In addition, consuming high-temperature cooked beef significantly increases the amount of AalphaC in urine, while consuming vegetables is associated with a decrease in AalphaC concentrations. Smoking half a pack of cigarettes is associated with a significant increase in the amount of AalphaC, which further confirms the biological activity of AalphaC and its association with dietary habits .
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- HY-W699983
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Imidazole- 15N2 (Glyoxaline- 15N2) is 15N labeled Imidazole. Imidazole (Glyoxaline; 1,3-Diaza-2,4-cyclopentadiene) is a heterocyclic aromatic compound. Imidazole bearing molecules have been used as corrosion, acetylcholinesterase (AChEI) and xanthine oxidase (XO) inhibitors, performing biological activities such as antifungal, antituberculosis, anti-inflammatory, antioxidant, and analgesic, amongst many others. Imidazole inhibits the enzymatic conversion of the endoperoxides (PGG2 and PGH2) to thromboxane A2 by platelet microsomes. Imidazole derivatives exhibits inhibition on SARS-CoV-2 3CL Pro enzyme, which is promising for research in the field of Alzheimer’s disease, gout, COVID-19 and thrombo-embolic disease .
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- HY-166904S
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2,2′,4,4′,6-Pentabromo diphenyl ether- 13C12 is 13C labeled 2,2′,4,4′,6-Pentabromo diphenyl ether .
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- HY-166926S
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2,2′,3,4,5,5′-Hexachloro diphenyl ether- 13C12 is 13C labeled 2,2′,3,4,5,5′-Hexachloro diphenyl ether .
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- HY-W748705
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Aminomethanephosphonic acid- 13C, 15N is 13C and 15N labeled (((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)methyl)phosphonic acid .
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- HY-W748299
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1, 2, 3, 6, 7, 8-Hexachloro-dibenzofuran- 13C12 is 13C labeled 1, 2, 3, 6, 7, 8-Hexachloro-dibenzofuran .
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- HY-W748291
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2,3,4,4',5-Pentachloro-1,1'-biphenyl- 13C12 (2,3,4,4',5-Pentachlorobiphenyl- 13C12) is 13C labeled 2,3,4,4',5-Pentachloro-1,1'-biphenyl .
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- HY-W748303
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1, 2, 3, 7, 8, 9-Hexachloro-dibenzofuran- 13C12 is 13C labeled 1, 2, 3, 7, 8, 9-Hexachloro-dibenzofuran .
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- HY-W748314
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2,2',6-Trichloro-1,1'-biphenyl- 13C12 is 13C labeled 2,2',6-Trichloro-1,1'-biphenyl .
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- HY-W748328
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Ixazomib- 13C2, 15N is 13C and 15N labeled Ixazomib. Ixazomib (MLN2238) is a selective, potent, and reversible proteasome inhibitor, which inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome with an IC50 of 3.4 nM (Ki of 0.93 nM) .
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-
- HY-W748332
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PCB118- 13C12 (CDE-99- 13C12; PCB No 118- 13C12; 2,3',4,4',5-Pentachlorobiphenyl- 13C12) is 13C labeled PCB118 .
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- HY-W748349
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2,2',3,3',4,4',5,5'-Octachloro-1,1'-biphenyl- 13C12 is 13C labeled 2,2',3,3',4,4',5,5'-Octachloro-1,1'-biphenyl .
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- HY-166897S
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1,2,3,4,8,9-Hexachlorodibenzofuran- 13C12 is 13C labeled 1,2,3,4,8,9-Hexachlorodibenzofuran .
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-
- HY-W748282
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2,3,3',4,4',5,5',6-Octachloro-1,1'-biphenyl- 13C12 is 13C labeled 2,3,3',4,4',5,5',6-Octachloro-1,1'-biphenyl .
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-
- HY-W748284
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2,4,4'-Trichloro-1,1'-biphenyl- 13C12 (2,4,4'-Trichlorobiphenyl- 13C12) is 13C labeled 2,4,4'-Trichloro-1,1'-biphenyl .
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-
- HY-W746828
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Oxindole-3-acetic acid- 13C6 is 13C labeled Oxindole-3-acetic acid .
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- HY-W749756
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rac-1,2-Distearoyl-3-chloropropanediol- 13C3 is 13C labeled rac-1,2-Distearoyl-3-chloropropanediol .
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- HY-166899S
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1,3-Dibromo-2,7,8-trichlorodibenzofuran- 13C12 is 13C labeled 1,3-Dibromo-2,7,8-trichlorodibenzofuran .
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-
- HY-166922S
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2,3,4,5-Tetrachloro-4′-methoxy biphenyl- 13C12 is 13C labeled 2,3,4,5-Tetrachloro-4′-methoxy biphenyl .
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- HY-166929S
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2,2′,3,4′,5,5′,6-Heptachloro-4-methoxy biphenyl- 13C12 is 13C labeled 2,2′,3,4′,5,5′,6-Heptachloro-4-methoxy biphenyl .
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-
- HY-166923S
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2-Chloro dibenzofuran- 13C12 is 13C labeled 2-Chloro dibenzofuran .
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-
- HY-166925S
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2′,3,3′,4′,5,5′-Hexachloro-4-biphenylol- 13C12 is 13C labeled 2′,3,3′,4′,5,5′-Hexachloro-4-biphenylol .
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- HY-166936S
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1,2,3,4,5,6,8-Heptachloronaphthalene- 13C10 is 13C labeled 1,2,3,4,5,6,8-Heptachloronaphthalene .
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-
- HY-166945S
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2,3,3′,4,5,5′-Hexachloro-4′-methoxy biphenyl- 13C12 is 13C labeled 2,3,3′,4,5,5′-Hexachloro-4′-methoxy biphenyl .
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-
- HY-166939S
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3,4,5,6-Tetrabromo[1,1′-biphenyl]-2,2′-diol- 13C12 is 13C labeled 3,4,5,6-Tetrabromo[1,1′-biphenyl]-2,2′-diol .
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- HY-166940S
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2′,3′,4′,5′-Tetrachloro-4-biphenylol- 13C12 is 13C labeled 2′,3′,4′,5′-Tetrachloro-4-biphenylol .
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- HY-166950S
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2,2′,3,4,4′,6-Hexabromo diphenyl ether- 13C12 is 13C labeled 2,2′,3,4,4′,6-Hexabromo diphenyl ether .
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- HY-166958S
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1,2,3,4,6,7,9-Heptachloro dibenzo-p-dioxin- 13C12 is 13C labeled 1,2,3,4,6,7,9-Heptachloro dibenzo-p-dioxin .
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- HY-W653930
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4,4'-Sulfonyldiphenol- 13C12 (Bisphenol S- 13C12) is 13C labeled 4,4'-Sulfonyldiphenol. 4,4'-Sulfonyldiphenol (Bisphenol S; Bis(4-hydroxyphenyl) sulfone) is a biochemical reagent that can be used as a biological material or organic compound for life science related research .
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- HY-W653962
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Triclosan- 13C6 is 13C labeled Triclosan. Triclosan is a broad-spectrum antibacterial agent that inhibits bacterial fatty acid synthesis at the enoyl-acyl carrier protein reductase (FabI) step. Triclosan inhibits E. coli enoyl-acyl carrier protein reductase (FabI) and FabI containing a glycine-to-valine substitution at position 93 (FabIG93V) with IC50s of 2 μM and 10 μM, respectively. Triclosan causes apoptotic effect in cultured rat neural stem cells (NSC). Triclosan exacerbates colitis and colitis-associated colorectal tumorigenesis in animal models .
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- HY-W653994
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Ethyl Paraben- 13C6 (Ethyl parahydroxybenzoate- 13C6) is 13C labeled Ethylparaben. Ethylparaben is the ethyl ester of paraben and is used as an antifungal preservative and food additive .
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- HY-W654020
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Propyl paraben- 13C6 (Propyl parahydroxybenzoate- 13C6) is 13C labeled Propylparaben. Propylparaben (Propyl parahydroxybenzoate) is an antibacterial preservative that can be produced by plants and bacteria. Propylparaben is commonly used in cosmetics, pharmaceuticals and foods. Propylparaben disrupts follicular growth and steroidogenic function by altering cell cycle, apoptosis and steroidogenic pathways. Propylparaben also reduced sperm count and motility in rats .
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- HY-W654041
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Adenosine monophosphate- 13C5 (AMP- 13C5) is 13C labeled Adenosine monophosphate. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction .
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- HY-W654118
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Cloxacillin- 13C4 (sodium) is 13C labeled Cloxacillin (sodium) .
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- HY-W654126
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Cytarabine- 13C3 (Cytosine β-D-arabinofuranoside- 13C3) is 13C labeled Cytarabine .
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- HY-W654258
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6-Mercaptopurine- 13C, 15N2 (hydrochloride) is 13C and 15N labeled 3,7-Dihydro-6h-purine-6-thione hydrochloride .
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- HY-W654304
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Oxonic Acid - 13C2, 15N3 (potassium salt hydrate) is 13C and 15N labeled Oxonic Acid (potassium salt hydrate) .
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- HY-W779296
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Potassium thiocyanate- 13C, 15N (Potassium rhodanide- 13C, 15N) is 13C and 15N labeled Potassium thiocyanate .
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- HY-W770410
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9-PAHSA- 13C4 is 13C labeled 9-PAHSA .
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- HY-W770434
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Octrizole- 13C6 is 13C labeled Octrizole .
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- HY-W770295
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2,3,4,5-Tetrabromobenzoic acid- 13C6 is 13C labeled 2,3,4,5-Tetrabromobenzoic acid .
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- HY-W769017
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Thiothiamine- 13C3 is 13C labeled Thiothiamine .
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- HY-W768398
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Ethephon- 13C2 is 13C labeled Ethephon. Ethephon is a plant growth regulator .
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- HY-W767866
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N-Acetyl-S-(2-carboxyethyl)cysteine- 13C3 (dicyclohexylamine) is 13C labeled N-Acetyl-S-(2-carboxyethyl)cysteine (dicyclohexylamine) .
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- HY-W767228
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Decitabine- 15N4 (5-Aza-2'-deoxy cytidine- 15N4) is 15N labeled Decitabine .
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- HY-W778144
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O,O-Diethyl Thiophosphate- 13C4 (ammonium) is 13C labeled O,O-Diethyl Thiophosphate (ammonium) .
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- HY-W778183
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3,5,6-Trichloro-2-pyridinol- 13C5 (TCPy- 13C5) is 13C labeled 3,5,6-Trichloro-2-pyridinol .
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- HY-W778142
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Dimethyl Phosphate- 13C2 (sodium) is 13C labeled Dimethyl Phosphate (sodium) .
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- HY-W753532
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Bisphenol B- 13C12 is 13C labeled Bisphenol B .
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- HY-W777533
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N-Acetyl sulfadiazine- 13C6 is 13C labeled N-Acetyl sulfadiazine .
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- HY-W777360
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Harman- 13C2, 15N is 13C and 15N labeled Harmane. Harmane is a benzodiazepine receptor inhibitor (IC50=7 μM), with IC50 values for mACh, Opioid Receptor, MAO-A/B, and α2-adrenergic receptor of 24 μM, 2.8 μM, 0.5 μM, 5 μM, and 18 μM, respectively. Harmane also inhibits haloperidol and serotonin, with IC50 values of 163 μM and 101 μM, respectively. Harmane inhibits the I1 imidazoline receptor (IC50=30 nM) to reduce blood pressure and has antidepressant, anti-anxiety, anticonvulsant, and analgesic effects. Harmane inhibits dopamine biosynthesis by decreasing tyrosine hydroxylase (TH) activity and enhancing L-DOPA-induced cytotoxicity in PC12 cells. Additionally, Harmane can increase the mutagenic effect induced by 2-acetylaminofluorene (AAF) .
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- HY-W777148
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Anagrelide- 13C3 (BL 4162A- 13C3) is 13C labeled Anagrelide .
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- HY-W777161
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Lamivudine- 15N2, 13C (BCH-189- 15N2, 13C) is 13C and 15N labeled Lamivudine .
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- HY-W780180
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Tetrabromobisphenol A- 13C12 is 13C labeled Tetrabromobisphenol A .
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- HY-166919S
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cis-Chlordane- 13C8 is 13C labeled cis-Chlordane .
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- HY-166924S
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1,2,3,4,6-Pentachloro-dibenzofuran- 13C12 is 13C labeled 1,2,3,4,6-Pentachloro-dibenzofuran .
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- HY-166895S
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1,3,4,6,8-Pentachloro dibenzofuran- 13C12 is 13C labeled 1,3,4,6,8-Pentachloro dibenzofuran .
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- HY-165695S
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2-Carbamoyl-3,5,6-trichloro-4-cyanobenzenesulfonate (sodium)- 15N2 is 15N labeled 2-Carbamoyl-3,5,6-trichloro-4-cyanobenzenesulfonate (sodium) .
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- HY-166893S
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1,2,3,6,7,8-Hexachloronaphthalene- 13C10 is 13C labeled 1,2,3,6,7,8-Hexachloronaphthalene .
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- HY-166901S
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2,3′,4,5,5′-Pentachloro-4′-methoxy biphenyl- 13C12 is 13C labeled 2,3′,4,5,5′-Pentachloro-4′-methoxy biphenyl .
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- HY-166915S
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1,4,6-Trichloro naphthalene- 13C10 is 13C labeled 1,4,6-Trichloro naphthalene .
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- HY-166953S
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1,2,3,4,6,8-Hexachloro-dibenzo-p-dioxin- 13C12 is 13C labeled 1,2,3,4,6,8-Hexachloro-dibenzo-p-dioxin .
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- HY-59354S1
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1,2-Dihydropyridazine-3,6-dione-3,4,5,6- 13C4 (1,2-Dihydro-3,6-pyridazine- 13C4-dione) is 13C labeled Maleic hydrazide. Maleic hydrazide is extensively used as a systemic plant growth regulator and as a herbicide. Maleic hydrazide acts as an inhibitor of the synthesis of nucleic acids and proteins .
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- HY-B1892S1
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Cefazolin- 13C2, 15N (Cephazolin- 13C2, 15N) is 13C and 15N labeled Cefazolin. Cefazolin (Cephazolin) is a first-generation cephalosporin antibiotic and can be used in varieties of bacterial infections research . Cefazolin has anti-inflammatory effect and can attenuate post-operative cognitive dysfunction (POCD) .
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- HY-W012507S1
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2,6-Dichlorobenzoic acid- 13C6 is 13C labeled 2,6-Dichlorobenzoic acid .
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- HY-165691S
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Chlorothalonil Metabolite R611553- 13C2, 15N2 (sodium salt) is 13C and 15N labeled Chlorothalonil Metabolite R611553 (sodium salt) .
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- HY-W011297S3
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Methyl arachidonate- 13C5 (Arachidonic acid methyl ester- 13C5) is 13C labeled Methyl arachidonate. Methyl arachidonate (Arachidonic acid methyl ester) is a fatty acid methyl ester resulting from the formal condensation of the carboxy group of arachidonic acid with methanol. Methyl arachidonate has activity of human blood serum metabolite .
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- HY-W128657S
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3-Chloro-2-hydroxypropanoic acid- 13C3 (2-Hydroxy-3-chloropropionic Acid- 13C3) is 13C labeled 3-Chloro-2-hydroxypropanoic acid .
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- HY-B2167S2
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Docosahexaenoic acid- 13C4 is 13C labeled Docosahexaenoic acid. Docosahexaenoic Acid (DHA) is an omega-3 fatty acid abundantly present brain and retina. It can be obtained directly from fish oil and maternal milk .
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- HY-14894S2
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Pragliflozin- 13C6 (ASP1941- 13C6) is 13C labeled Ipragliflozin. Ipragliflozin (ASP1941) is an orally active and selective SGLT2 inhibitor with IC50s of 7.38 and 1876 nM, 6.73 and 1166 nM, 5.64 and 1380 nM for human SGLT2 and SGLT1, rat SGLT2 and SGLT1, mouse SGLT2 and SGLT1, respectively. Antidiabetic agent .
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- HY-113455S1
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9(S)-HODE- 13C18 ((+)-α-Dimophecolic acid- 13C18) is 13C labeled 9S-HODE. 9S-HODE (Alpha-dimorphecolic acid) is an octadecadienoic acid and the main active derivative of linoleic acid, which can reduce the viability of HL-60 cells and induce apoptosis. 9S-HODE is rich in lipid peroxidation (LPO) products and is almost an ideal marker for LPO .
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- HY-B0660S1
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Eicosapentaenoic acid 1,2,3,4,5- 13C5 (EPA 1,2,3,4,5- 13C, FA 20:5- 13C5) is 13C labeled Eicosapentaenoic Acid. Eicosapentaenoic Acid (EPA) is an orally active Omega-3 long-chain polyunsaturated fatty acid (ω-3 LC-PUFA). Eicosapentaenoic Acid exhibits a DNA demethylating action that promotes the re-expression of the tumor suppressor gene CCAAT/enhancer-binding protein δ (C/EBPδ). Eicosapentaenoic Acid activates RAS/ERK/C/EBPβ pathway through H-Ras intron 1 CpG island demethylation in U937 leukemia cells. Eicosapentaenoic Acid can promote relaxation of vascular smooth muscle cells and vasodilation .
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- HY-166960S
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2,2′,4,4′-Tetrabromo-6-hydroxydiphenyl ether- 13C12 is 13C labeled 2,2′,4,4′-Tetrabromo-6-hydroxydiphenyl ether .
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- HY-166961S
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2′,4′,5′-Trichloro-4-biphenylol- 13C12 is 13C labeled 2′,4′,5′-Trichloro-4-biphenylol .
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- HY-166900S
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3,3′,4,5′-Tetrabromodiphenyl ether- 13C12 is 13C labeled 3,3′,4,5′-Tetrabromodiphenyl ether .
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- HY-166889S
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2,4,5-Trichloro-4'-methoxy-biphenyl- 13C12 is 13C labeled 2,4,5-Trichloro-4'-methoxy-biphenyl .
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- HY-N7082S
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D- Arabinose- 13C5 is 13C labeled D- Arabinose. D-Arabinose, a monosaccharide, shows strong growth inhibition against the Caenorhabditis elegans with an IC50 of 7.5 mM .
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- HY-166933S
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1,2,3,6,7-Pentachloro-naphthalene- 13C10 is 13C labeled 1,2,3,6,7-Pentachloro-naphthalene .
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- HY-166927S
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2,2′,4,4′,5-Pentabromo diphenyl ether- 13C12 is 13C labeled 2,2′,4,4′,5-Pentabromo diphenyl ether .
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- HY-166912S
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1,2,3,5,6,7-Hexachloro-naphthalene- 13C10 is 13C labeled 1,2,3,5,6,7-Hexachloro-naphthalene .
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- HY-166914S
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2,2',3,3',4,5,5'-Heptachloro-4'-methoxybiphenyl- 13C12 is 13C labeled 2,2',3,3',4,5,5'-Heptachloro-4'-methoxybiphenyl .
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- HY-166903S
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2,3,4,5-Tetrachlorodiphenyl ether- 13C12 is 13C labeled 2,3,4,5-Tetrachlorodiphenyl ether .
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- HY-166918S
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2,3,6,7-Tetrachloro biphenylene- 13C12 is 13C labeled 2,3,6,7-Tetrachloro biphenylene .
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- HY-166962S
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2,3-Dichloro dibenzofuran- 13C12 is 13C labeled 2,3-Dichloro dibenzofuran .
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- HY-10450S5
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Dapagliflozin- 13C6-1 is 13C labeled Dapagliflozin. Dapagliflozin (BMS-512148), a new type of agent used to treat diabetes mellitus (DM), is a competitive sodium/glucose cotransporter 2 (SGLT2) inhibitor, which results in excretion of glucose into the urine . Dapagliflozin induces HIF1 expression and attenuates renal IR injury .
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- HY-166920S
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2,2′,3,4,5-Pentachlorodiphenyl ether- 13C12 is 13C labeled 2,2′,3,4,5-Pentachlorodiphenyl ether .
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- HY-166935S
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2,3-Dibromo-7,8-dichloro-dibenzofuran- 13C12 is 13C labeled 2,3-Dibromo-7,8-dichloro-dibenzofuran .
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- HY-166942S
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1,2,3,8,9-Pentachloro-dibenzo-p-dioxin- 13C12 is 13C labeled 1,2,3,8,9-Pentachloro-dibenzo-p-dioxin .
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- HY-166948S
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1,2,3,8,9-Pentachloro dibenzofuran- 13C12 is 13C labeled 1,2,3,8,9-Pentachloro dibenzofuran .
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- HY-166949S
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1,2,8,9-Tetrachloro-dibenzo-p-dioxin- 13C12 is 13C labeled 1,2,8,9-Tetrachloro-dibenzo-p-dioxin .
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- HY-166952S
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2′,3,4′,5,5′-Pentachloro-4-biphenylol- 13C12 is 13C labeled 2′,3,4′,5,5′-Pentachloro-4-biphenylol .
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- HY-166951S
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1,2,4,7,8-Pentachloro dibenzo-p-dioxin- 13C12 is 13C labeled 1,2,4,7,8-Pentachloro dibenzo-p-dioxin .
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- HY-W010450S5
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Thymine- 13C5, 15N2 (5-Methyluacil- 13C5, 15N2) is 13C and 15N labeled Thymine. Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a Km of 2.3 μM .
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- HY-W010256S3
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D-Xylulose-13C5 is 13C labeled D-Xylulose. D-xylulose is the precursor of arabinitol .
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- HY-W753141
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p,p'-DDE- 13C12 is 13C labeled p,p'-DDE. p,p'-DDE (4,4'-DDE), a major metabolite of persistent dichlorodiphenyltrichloroethane (DDT), is a potent androgen receptor antagonist, with an IC50 of 5 μM and a Ki of 3.5 μM .
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- HY-W779345
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3,3',5'-Triiodo-L-thyronine- 13C6 is 13C labeled 3,3',5'-Triiodo-L-thyronine .
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- HY-W015466S1
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Acetylvaline-13C2 is the 13C-labeled Acetylvaline. Acetylvaline is an endogenous metabolite .
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- HY-P0265AS
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β-Amyloid- 15N (1-40) (TFA) is the 15N-labledβ-Amyloid (1-40) (TFA). β-Amyloid (1-40) is a primary protein in plaques found in the brains of patients with Alzheimer's disease[1].
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- HY-P1363S
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β-Amyloid- 15N (1-42), human (TFA) is the 15N-labledβ-Amyloid (1-42) (TFA). β-Amyloid (1-42), human TFA (Amyloid β-Peptide (1-42) (human) TFA) is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease[1].
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- HY-P3146S
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FTISADTSK- 13C6, 15N2 TFA is 13C- and 15N-labeled FTISADTSK (HY-P3146). FTISADTSK is an endogenous stable signature peptide from Trastuzumab monitored by selected reaction monitoring (SRM) .
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- HY-P0014S1
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Liraglutide- 13C5, 15N (tetraTFA) is the 13C and 15N labeled Liraglutide (HY-P0014) . Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used clinically to treat type 2 diabetes mellitus .
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- HY-P2625S1
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GLP-2(3-33) (Leu- 13C6, 15N) TFA is 13C and 15N labeled GLP-2(3-33) (HY-P2625). GLP-2(3-33), generated naturally by dipeptidylpeptidase IV (DPPIV), acts as a partial agonist on GLP-2 receptor (EC50=5.8 nM).
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- HY-P1142S1
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GLP-2(rat) (Ala- 13C3, 15N) TFA is 13C and 15N labeled GLP-2(rat) (HY-P1142). GLP-2(rat) is an intestinal growth factor. GLP-2(rat) stimulates cell proliferation and inhibits apoptosis. GLP-2(rat) enhances mucosal mass and function in residual small intestine after massive small bowel resection (MSBR).
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- HY-P1142S
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GLP-2(rat) (Ala- 13C3, 15N) is 13C and 15N labeled GLP-2(rat) (HY-P1142). GLP-2(rat) is an intestinal growth factor. GLP-2(rat) stimulates cell proliferation and inhibits apoptosis. GLP-2(rat) enhances mucosal mass and function in residual small intestine after massive small bowel resection (MSBR).
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- HY-P2625S
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GLP-2(3-33) (Leu- 13C6, 15N) is 13C and 15N labeled GLP-2(3-33) (HY-P2625). GLP-2(3-33), generated naturally by dipeptidylpeptidase IV (DPPIV), acts as a partial agonist on GLP-2 receptor (EC50=5.8 nM).
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- HY-156341S1
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LLIYYTSSLHSGVPSR-(Arg- 13C6, 15N4) (TFA) is the peptide containing 13C- and 15N-labeled Arg.
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- HY-156343S1
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SNNYATHYAESVK-(Lys- 13C6, 15N2) (TFA) is the peptide containing 13C- and 15N-labeled Lys.
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- HY-156344S1
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GLEWVAEIR-(Arg- 13C6, 15N4) (TFA) is the peptide containing 13C- and 15N-labeled Arg.
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- HY-156345S1
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LPFTFGQGTK-(Lys- 13C6, 15N2) TFA is the peptide containing 13C- and 15N-labeled Lys.
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- HY-P5201S1
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VTSEGAGLQLQK- 13C6, 15N2 (TFA) is the 13C- and 15N-labeled VTSEGAGLQLQK. VTSEGAGLQLQK is an amino acid sequence in the C-terminal region of recombinant human alpha-acid glucosidase (rhGAA), which can be used to bind anti-drug antibodies in plasma and quantitatively analyze the therapeutic effect .
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- HY-P0014S2
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Liraglutide- 13C6, 15N (TFA)is the 13C and 15N labeledLiraglutide(HY-P0014). Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used clinically to treat type 2 diabetes mellitus .
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- HY-163426S
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AFFGHYLYEVAR-(Arg- 13C6, 15N4) is 13C and 15N labeled AFFGHYLYEVAR-(Arg) .
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- HY-163427S
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FNLEALVTHTLPFEK-(Lys- 13C6, 15N2) is 13C and 15N labeled FNLEALVTHTLPFEK-(Lys) .
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- HY-163423S
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TELAEPTSTR-(Arg- 13C6, 15N4) is 13C and 15N labeled TELAEPTSTR-(Arg).
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- HY-163422S
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PHSHPALTPEQK-(Lys- 13C6, 15N2) is 13C and 15N labeled PHSHPALTPEQK-(Lys).
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- HY-163424S
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SSVFVADPK-(Lys- 13C6, 15N2) is 13C and 15N labeled SSVFVADPK-(Lys).
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- HY-163425S
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AILNYVANK-(Lys- 13C6, 15N2) is 13C and 15N labeled AILNYVANK-(Lys) .
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- HY-P1032S
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Angiotensin I- 13C19, 15N3 (human, mouse, rat) is the 13C and 15N labeled Angiotensin I (human, mouse, rat) (HY-P1032). Cellulose (Pectin glycosidase) is a natural high molecular weight polysaccharide found in many plants and organisms. It is widely used in manufacturing industries, such as in paper making, textiles, food and medicine, etc. As a renewable resource, Cellulose is biodegradable and sustainable, and can also be used to manufacture chemicals such as Cellulose Esters, Cellulose Acetate and Cellulose Nitrate. In addition, Cellulose is often used as a food additive to increase the stability and quality of food .
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- HY-P10324
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TAT-p16 (p16INK4a peptide) is a peptide mimic of p16INK4a that can induce an early G phase cell cycle arrest in the absence of active cyclin E:Cdk2 complex .
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- HY-158994S
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MEGDSRGG-(Ala- 13C3, 15N)-GGEA-(Leu- 13C6, 15N)-DPESAASSLSGAS TFA is a 13C- and 15N-labeled peptide containing 13C3, 15N-labeled alanine (Ala) and 13C6, 15N-labeled leucine (Leu).
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- HY-158992S
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SP-(Val- 13C5, 15)-EKNQ-(Leu- 13C6, 15)-TIDFINIVKDPVPHNEYKT TFA is a 13C- and 15N-labeled peptide containing 13C5, 15N-labeled valine (Val) and 13C6, 15N-labeled leucine (Leu).
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- HY-P3207S
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DLPLTFGGGT-Lys-13C6,15N2 (TFA) is a deuterated labeled DLPLTFGGGTK .
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- HY-P1033S
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Pyr1]-Apelin-13, Gly(15N) TFA is a Gly 15N labeled [Pyr1]-Apelin-13. [Pyr1]-Apelin-13 is a highly potent, selective endogenous apelin receptor agonist .
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- HY-P6421S
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LGPLVEQG-Arg( 13C6, 15N4) TFA is a peptide containing 13C6 and 15N4 labeled Arg .
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- HY-P6422S
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LAVYQAGA-Arg( 13C6, 15N4) TFA is a peptide containing 13C6 and 15N4 labeled Arg .
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- HY-P6424S
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LGADMEDVCG-Arg( 13C6, 15N4) TFA is a peptide containing 13C6 and 15N4 labeled Arg .
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- HY-P6425S
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LCADMEDV-Arg( 13C6, 15N4) TFA is a peptide containing 13C6 and 15N4 labeled Arg .
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- HY-P6423S
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CLAVYQAGA-Arg( 13C6, 15N4) TFA is a peptide containing 13C6 and 15N4 labeled Arg .
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- HY-P1032S2
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Angiotensin I-13C6,15N (human, mouse, rat) TFA is 13C and 15N labeled Angiotensin I (human, mouse, rat) TFA. Angiotensin I-13C6,15N (human, mouse, rat) TFA is a precursor of angiotensin II and is cleaved into angiotensin II by angiotensin converting enzyme (ACE) .
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- HY-P0090S
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Calcitonin- 13C6, 15N4 (salmon) (Salmon calcitonin- 13C6, 15N4) TFA is 13C and 15N-labeled Calcitonin (salmon) (HY-P0090). Calcitonin (salmon) , a calcium regulating hormone, is a dual-action amylin and calcitonin receptor agonist, could stimulate bone formation and inhibit bone resorption .
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- HY-W127841
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Citric acid-2,4-13C2 (Sodium Lauryl Sulfate) is a labeled citric acid. Citric acid is found in many fruits and vegetables, especially citrus fruits. It participates in biological processes in the body, such as the citric acid cycle.
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| Cat. No. |
Product Name |
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Classification |
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- HY-136205
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Iodoacetamide-alkyne; N-Hex-5-ynyl-2-iodo-acetamide
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Alkynes
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IA-Alkyne (Iodoacetamide-alkyne; N-Hex-5-ynyl-2-iodo-acetamide) is a TRP channel (TRPC) agonist and has the potential for the study of respiratory infection . IA-Alkyne can be used to develop an isotopically tagged probe for quantitative cysteine-reactivity profiling . IA-Alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-14605BS
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AGN1135-13C3; TVP1012-13C3 racemic
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Alkynes
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Rasagiline- 13C3 (mesylate racemic) is a 13C-labeled Rasagiline mesylate racemic. Rasagiline mesylate racemic is a highly potent selective irreversible mitochondrial monoamine oxidase (MAO) inhibitor[1]. Rasagiline-13C3 (mesylate racemic) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-50896S1
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CP-358774-13C6; NSC 718781-13C6; OSI-774-13C6
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Alkynes
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Erlotinib- 13C6 is a 13C-labeled Erlotinib. Erlotinib is a directly acting EGFR tyrosine kinase inhibitor, with an IC50 of 2 nM for human EGFR[1].
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- HY-136380S
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Alkynes
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Clodinafop-propargyl- 13C6 is the 13C-labeled Clodinafop-propargyl. Clodinafop-propargyl, a main member of aryloxyphenoxy-propionate herbicides, is used for postemergence control of annual grasses in cereals, including Avena, Lolium, Setaria, Phalaris and Alopecurus spp[1]. Clodinafop-propargyl-13C6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-140346AS
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Azide
PROTAC Synthesis
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L-Azidohomoalanine-1,2,3,4- 13C4 (hydrochloride) is the 13C- and 15N-labeled L-Azidohomoalanine hydrochloride. L-Azidohomoalanine hydrochloride is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. L-Azidohomoalanine-1,2,3,4-13C4 (hydrochloride) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- HY-B0216S2
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17α-Ethynylestradiol-13C2; Ethynylestradiol-13C2
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Alkynes
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Ethynyl Estradiol- 13C2 is the 13C-labeled Ethynyl Estradiol. Ethynyl Estradiol-13C2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-12008S1
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CP-358774-13C6 hydrochloride; NSC 718781-13C6 hydrochloride; OSI-774-13C6 hydrochloride
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Alkynes
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Erlotinib- 13C6 (hydrochloride) is the 13C labeled Erlotinib Hydrochloride[1]. Erlotinib Hydrochloride (CP-358774 Hydrochloride) inhibits purified EGFR kinase with an IC50 of 2 nM[2]. Erlotinib-13C6 (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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