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DL-Glyceraldehyde-<sup>13</sup>C,d

" in MedChemExpress (MCE) Product Catalog:

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Click Chemistry:	Labeling and Fluorescence Imaging (1) Azide (3) Alkynes (5)
Oligonucleotides:	Aptamers (2) Rat Pre-designed siRNA Sets (4) CpG ODNs (8) mRNA (3) Mouse Pre-designed siRNA Sets (4) Solubilizing Agents (1) Cationic Lipids (1) Phospholipids (1) Human Pre-designed siRNA Sets (92) Antisense Oligonucleotides (2) siRNAs (100)

2048

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

100

Peptides

MCE Kits

544

Inhibitory Antibodies

Natural
Products

2334

Recombinant Proteins

1022

Isotope-Labeled Compounds

293

Antibodies

Click Chemistry

119

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-128748

*DL-Glyceraldehyde*	Endogenous Metabolite	Others
DL-Glyceraldehyde is a bioactive substance involved in cellular energy metabolism and a key intermediate in sugar metabolism pathways (such as glycolysis and gluconeogenesis). During glycolysis, DL-Glyceraldehyde is converted by enzymes into other metabolites to provide energy for cells; during gluconeogenesis, DL-Glyceraldehyde participates in the synthesis of glucose as a precursor. In the field of medical research, DL-Glyceraldehyde can be used to study diseases related to sugar metabolism, such as diabetes, tumors, etc[1][2].

HY-113054

DL-Glyceraldehyde 3-phosphate	Acyltransferase Bacterial Endogenous Metabolite	Infection Metabolic Disease
DL-Glyceraldehyde 3-phosphate is an intermediate in several metabolic pathways, including glycolysis and gluconeogenesis. DL-Glyceraldehyde 3-phosphate is a potent inhibitor of the growth of *E. coli. DL-Glyceraldehyde* 3-phosphate is a competitive inhibitor of the acyltransferase .

HY-128748S2

DL-Glyceraldehyde-13C,d	Isotope-Labeled Compounds Endogenous Metabolite	Others
DL-Glyceraldehyde- ¹³C,d is the deuterium and ¹³C labeled DL-Glyceraldehyde[1].

HY-131921

DL-Glyceraldehyde 3-phosphate diethyl acetal barium	Biochemical Assay Reagents	Endocrinology
DL-Glyceraldehyde 3-phosphate diethyl acetal barium is an Aspartate Aminotransferase isozyme inhibitor .

HY-128748S4

DL-Glyceraldehyde-13C3	Isotope-Labeled Compounds	Others
DL-Glyceraldehyde- ¹³C₃ is the ¹³C labled DL-Glyceraldehyde (HY-128748) . DL-Glyceraldehyde is an organic compound.

HY-128748S

DL-Glyceraldehyde-1-13C	Isotope-Labeled Compounds Endogenous Metabolite	Others
DL-Glyceraldehyde-1- ¹³C is the ¹³C labeled DL-Glyceraldehyde[1].

HY-128748S1

DL-Glyceraldehyde-2-13C	Isotope-Labeled Compounds Endogenous Metabolite	Others
DL-Glyceraldehyde-2- ¹³C is the ¹³C labeled DL-Glyceraldehyde[1].

HY-W145525

DL-Glyceraldehyde diethyl acetal 3,3-Diethoxy-1,2-propanediol	Biochemical Assay Reagents	Others
DL-Glyceraldehyde Diethyl Acetal is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-165662S

Pranoprofen-13C-d3 Pyaopofe-<sup>13sup>C-d₃; Y 8004-<sup>13sup>C-d₃	Isotope-Labeled Compounds	Others
Pranoprofen- ¹³C-d₃ (Pyaopofe- ¹³C-d₃) is ¹³C and deuterium labeled Pranoprofen .

HY-B0202S4

Irbesartan-13C,d4 SR-47436-<sup>13sup>C,d₄; BMS-186295-<sup>13sup>C,d₄	Angiotensin Receptor Apoptosis Isotope-Labeled Compounds	Cardiovascular Disease
Irbesartan- ¹³C,d₄ (SR-47436- ¹³C,d₄; BMS-186295- ¹³C,d₄) is ¹³C-labeled Irbesartan (HY-B0202) .

HY-B0389S19

D-Glucose-13C,d Glucose-<sup>13sup>C,d; D-(+)-Glucose-<sup>13sup>C,d; Dextrose-<sup>13sup>C,d	Endogenous Metabolite	Metabolic Disease Cancer
D-Glucose- ¹³C,d is the deuterium and ¹³C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical sign

HY-10219S1

Rapamycin-13C,d3 Sirolimus-<sup>13sup>C,d₃; AY-22989-<sup>13sup>C,d₃	Isotope-Labeled Compounds mTOR FKBP Autophagy	Cancer
Rapamycin- ¹³C,d₃ (Sirolimus- ¹³C,d₃; AY-22989- ¹³C,d₃) is the ¹³C and deuterium labeled Rapamycin (HY-10219) .Rapamycin is a potent and specific mTOR inhibitor with an IC₅₀ of 0.1 nM in HEK293 cells. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1. Rapamycin is an autophagy activator, an immunosuppressant .

HY-13318S1

Oseltamivir acid-13C,d3 GS 4071-<sup>13sup>C,d₃; Ro 64-0802-<sup>13sup>C,d₃; Oseltamivir carboxylate-<sup>13sup>C,d₃	Isotope-Labeled Compounds Drug Metabolite Influenza Virus	Infection
Oseltamivir acid-13C,d3 (GS 4071-13C,d3; Ro 64-0802-13C,d3) is a 13C- and deuterium-labeled Oseltamivir acid (HY-13318). Oseltamivir acid is the active metabolite of Oseltamivir phosphate and inhibits influenza virus neuraminidase (IC₅₀=2 nM). Oseltamivir acid is orally active and can be used to study influenza A/B infections .

HY-W011240S

Hydroflumethiazide-13C,d2 Methforylthiazidine-<sup>13sup>C,d₂; Rontyl-<sup>13sup>C,d₂	Isotope-Labeled Compounds	Others
Hydroflumethiazide- ¹³C,d₂ is the deuterium and ¹³C labeled Hydroflumethiazide[1].

HY-N0378S6

D-Mannitol-13C,d2 Mannitol-<sup>13sup>C,d₂; Mannite-<sup>13sup>C,d₂	Isotope-Labeled Compounds Apoptosis Endogenous Metabolite	Metabolic Disease Cancer
D-Mannitol- ¹³C,d₂ is the deuterium and ¹³C labeled D-Mannitol.

HY-B0002BS2

Ondansetron-13C,d3 GR 38032-<sup>13sup>C,d₃; SN 307-<sup>13sup>C,d₃	Isotope-Labeled Compounds 5-HT Receptor	Neurological Disease
Ondansetron- ¹³C,d₃ is the ¹³C- and deuterium labeled Ondansetron[1].

HY-15651S

Alvelestat-13C,d3 AZD9668-<sup>13sup>C,d₃	Elastase Isotope-Labeled Compounds	Inflammation/Immunology
Alvelestat- ¹³C,d₃ (AZD9668- ¹³C,d₃) is ¹³C-labeled Alvelestat (HY-15651) .

HY-W754842

Saxagliptin-13C,d2-1 hydrochloride BMS-477118-<sup>13sup>C,d₂ hydrochloride	Isotope-Labeled Compounds	Others
Saxagliptin- ¹³C,d₂-1 (BMS-477118- ¹³C,d₂) hydrochloride is ¹³C and deuterium labeled Saxagliptin (hydrochloride) .

HY-17413S1

Zidovudine-13C,d3 Azidothymidine-<sup>13sup>C,d₃; AZT-<sup>13sup>C,d₃; ZDV-<sup>13sup>C,d₃	Isotope-Labeled Compounds HIV CRISPR/Cas9	Infection
Zidovudine- ¹³C,d₃ is the ¹³C- and deuterium labeled Zidovudine. Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection. Zidovudine increases CRISPR/Cas9-mediated editing frequency. Zidovudine-13C,d3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-13693S2

Mometasone furoate-13C,d6 Sch32088-<sup>13sup>C,d₆	Glucocorticoid Receptor Isotope-Labeled Compounds	Cancer
Mometasone furoate- ¹³C,d₆ (Sch32088- ¹³C,d₆) is ¹³C-labeled Mometasone furoate (HY-13693) .

HY-B0330S2

Levofloxacin-13C,d3 (-)-Ofloxacin-<sup>13sup>C,d₃	Isotope-Labeled Compounds Bacterial Antibiotic	Infection
Levofloxacin- ¹³C,d₃ is the ¹³C- and deuterium labeled Levofloxacin.

HY-125818S2

Cytidine-5'-triphosphate-13C,d1 dilithium Cytidine triphosphate-<sup>13sup>C,d<sup>1sup> dilithium; 5'-CTP-<sup>13sup>C,d<sup>1sup> dilithium	Isotope-Labeled Compounds DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Endogenous Metabolite	Infection Cancer
Cytidine-5'-triphosphate- ¹³C,d₁ (Cytidine triphosphate- ¹³C,d₁ dilithium; 5'-CTP- ¹³C,d₁) dilithium is deuterium and ¹³C-labeled Cytidine-5'-triphosphate (HY-125818). Cytidine 5′-triphosphate (Cytidine triphosphate; 5'-CTP) is a nucleoside triphosphate and serves as a building block for nucleotides and nucleic acids, lipid biosynthesis. Cytidine triphosphate synthase can catalyze the formation of cytidine 5′-triphosphate from uridine 5′-triphosphate (UTP). Cytidine 5′-triphosphate is an essential biomolecule?in the de novo?pyrimidine biosynthetic pathway in?T. gondii.

HY-W777599

(±)-Naproxen-13C,d3-1 (Rac)-Naproxen-<sup>13sup>C,d₃-1	Isotope-Labeled Compounds	Others
(±)-Naproxen- ¹³C,d₃-1 ((Rac)-Naproxen- ¹³C,d₃-1) is ¹³C and deuterium labeled (±)-Naproxen .

HY-121259S

Doxorubicinol-13C,d3 TFA Adriamycinol-<sup>13sup>C,d₃ TFA; DXR-OL-<sup>13sup>C,d₃ TFA	Endogenous Metabolite	Others
Doxorubicinol- ¹³C,d₃ (TFA) is the deuterium and ¹³C labeled Doxorubicinol TFA[1].

HY-13683S1

Mifepristone-13C,d3 RU486-<sup>13sup>C,d₃; RU 38486-<sup>13sup>C,d₃	Isotope-Labeled Compounds Progesterone Receptor Glucocorticoid Receptor NO Synthase Autophagy	Endocrinology Cancer
Mifepristone- ¹³C,d₃ is the ¹³C- and deuterium labeled Mifepristone. Mifepristone (RU486) is a progesterone receptor (PR) and glucocorticoid receptor (GR) antagonist with IC50s of 0.2 nM and 2.6 nM in in vitro assay[1]. Mifepristone-13C,d3 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-B0389S25

D-Glucose-13C,d1 Glucose-<sup>13sup>C,d₁; D-(+)-Glucose-<sup>13sup>C,d₁; Dextrose-<sup>13sup>C,d₁	Endogenous Metabolite	Metabolic Disease Cancer
D-Glucose- ¹³C,d is the deuterium and ¹³C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical sig

HY-G0007S1

Omeprazole sulfone-13C,d3 Omeprazole sulfone-<sup>13sup>C,d₃; Omeprazole sulphone-<sup>13sup>C,d₃	Isotope-Labeled Compounds Drug Metabolite	Others
Omeprazole metabolite Omeprazole sulfone- ¹³C,d₃ is the deuterium and ¹³C labeled Omeprazole metabolite Omeprazole sulfone[1].

HY-B0740S1

Cyclobenzaprine-13C,d3 hydrochloride MK130-<sup>13sup>C,d₃ hydrochloride	Isotope-Labeled Compounds 5-HT Receptor	Neurological Disease
Cyclobenzaprine- ¹³C,d₃ (hydrochloride) is the ¹³C- and deuterium labeled Cyclobenzaprine (hydrochloride).

HY-B0192S1

Alfuzosin-13C,d3 SL 77499-<sup>13sup>C,d₃	Isotope-Labeled Compounds Adrenergic Receptor	Endocrinology
Alfuzosin- ¹³C,d₃ is the ¹³C- and deuterium labeled Alfuzosin.

HY-18252S

Avanafil-13C,d3 TA1790-<sup>13sup>C,d₃	Isotope-Labeled Compounds Phosphodiesterase (PDE)	Cardiovascular Disease
Avanafil- ¹³C,d₃ is the ¹³C- and deuterium labeled Avanafil.

HY-B0389S21

D-Glucose-13C,d2 Glucose-<sup>13sup>C,d₂; D-(+)-Glucose-<sup>13sup>C,d₂; Dextrose-<sup>13sup>C,d₂	Endogenous Metabolite	Metabolic Disease Cancer
D-Glucose- ¹³C,d₂ is the deuterium and ¹³C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical sig

HY-111772S

Elexacaftor-13C,d3 VX-445-<sup>13sup>C,d₃	Isotope-Labeled Compounds	Inflammation/Immunology
Elexacaftor- ¹³C,d₃ is the deuterium labeled Elexacaftor (HY-111772)[1].

HY-B0621S1

Triclabendazole-13C,d3 CGA89317-<sup>13sup>C,d₃	Isotope-Labeled Compounds Microtubule/Tubulin Parasite	Infection
Triclabendazole- ¹³C,d₃ is the ¹³C- and deuterium labeled Triclabendazole[1].

HY-17506S1

Azithromycin-13C,d3 CP 62993-<sup>13sup>C,d₃	Bacterial Autophagy Antibiotic Isotope-Labeled Compounds	Others
Azithromycin- ¹³C,d₃ is the deuterium and ¹³C labeled Azithromycin[1].

HY-B0457S2

Clomipramine-13C,d3 hydrochloride Chlorimipramine-<sup>13sup>C,d₃ hydrochloride; G-34586-<sup>13sup>C,d₃ hydrochloride; NSC-169865-<sup>13sup>C,d₃ hydrochloride	Isotope-Labeled Compounds Serotonin Transporter	Neurological Disease
Clomipramine- ¹³C,d₃ (hydrochloride) is the ¹³C- and deuterium labeled Clomipramine (hydrochloride). Clomipramine (Chlorimipramine) hydrochloride is a potent 5-HT reuptake blocker with the IC50 value of 1.5 nM. Clomipramine hydrochloride is a tricyclic antidepressant that can be used for the research of depression and obsessive compulsive disorder (OCD)[1].

HY-14855S

Tedizolid-13C,d3 TR 700-<sup>13sup>C,d₃; Torezolid-<sup>13sup>C,d₃; DA-7157-<sup>13sup>C,d₃	Isotope-Labeled Compounds Bacterial Antibiotic	Infection
Tedizolid- ¹³C,d₃ is the ¹³C- and deuterium labeled Tedizolid. Tedizolid (TR 700; Torezolid; DA-7157) is a novel oxazolidinone, acting through inhibition of bacterial protein synthesis by binding to 23S ribosomal RNA (rRNA) of the 50S subunit of the ribosome.

HY-A0023AS

Alogliptin-13C,d3 SYR-322-<sup>13sup>C,d₃	Isotope-Labeled Compounds Dipeptidyl Peptidase	Metabolic Disease Cancer
Alogliptin- ¹³C,d₃ is the deuterium labeled Alogliptin. Alogliptin is a potent and selective inhibitor of DPP-4.

HY-90001S1

Ritonavir-13C,d3 ABT 538-<sup>13sup>C,d₃; RTV-<sup>13sup>C,d₃	HIV Protease HIV SARS-CoV Apoptosis	Infection
Ritonavir- ¹³C,d₃ is the ¹³C- and deuterium labeled Ritonavir. Ritonavir (ABT 538) is an inhibitor of HIV protease used to treat HIV infection and AIDS. Ritonavir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 1.61 μM.

HY-10284S1

Linagliptin-13C,d3 BI 1356-<sup>13sup>C,d₃	Isotope-Labeled Compounds Dipeptidyl Peptidase Autophagy Ferroptosis	Metabolic Disease
Linagliptin- ¹³C,d₃ is the ¹³C- and deuterium labeled Linagliptin. Linagliptin is a highly potent, selective DPP-4 inhibitor with IC50 of 1 nM. Linagliptin-13C,d3 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-B0596S

Taltirelin-13C,d3 TA-0910-<sup>13sup>C,d₃	Isotope-Labeled Compounds Thyroid Hormone Receptor Apoptosis	Neurological Disease Endocrinology
Taltirelin- ¹³C,d₃ (TA-0910- ¹³C,d₃) is ¹³C and deuterated labeled Taltirelin (HY-B0596). Taltirelin (TA0910) is a superagonist at thyrotropin-releasing hormone receptor (TRH-R) with an IC₅₀ of 910 nM and EC₅₀ of 36 nM for stimulating an increase in cytosolic Ca ²⁺ concentration (Ca ²⁺ release).

HY-10285S1

(rel)-Saxagliptin-13C,d2 TFA (rel)-BMS-477118-<sup>13sup>C,d₂ TFA	Dipeptidyl Peptidase Isotope-Labeled Compounds	Metabolic Disease
(rel)-Saxagliptin- ¹³C,d₂ ((rel)-BMS-477118- ¹³C,d₂) TFA is ¹³C-labeled Saxagliptin (HY-10285) .

HY-10250S

Triciribine phosphate-13C,d3 TCN-P-<sup>13sup>C,d₃	Isotope-Labeled Compounds	Others
Triciribine phosphate-- ¹³C,d₃ is the deuterium and ¹³C labeled Triciribine phosphate[1].

HY-66011AS4

Moxifloxacin-13C,d3 hydrochloride BAY 12-8039-<sup>13sup>C,d₃	Isotope-Labeled Compounds	Cancer
Moxifloxacin- ¹³C,d₃ hydrochloride (BAY 12-8039- ¹³C,d₃) is ¹³C and deuterated labeled Moxifloxacin (HY-66011A). Moxifloxacin is an orally active 8-methoxyquinolone antimicrobial for use in the treatment of acute bacterial sinusitis, acute bacterial exacerbations of chronic bronchitis, and community-acquired pneumonia.

HY-126857AS1

5-Hydroxyomeprazole-13C,d2 sodium Hydroxyomeprazole-<sup>13sup>C,d₂ sodium	Isotope-Labeled Compounds Drug Metabolite	Others
5-Hydroxyomeprazole- ¹³C,d₂ sodium is ¹³C and deuterated labeled 5-Hydroxyomeprazole sodium (HY-126857A).

HY-13756S

Tacrolimus-13C,d2 FK506-<sup>13sup>C,d₂; Fujimycin-<sup>13sup>C,d₂; FR900506-<sup>13sup>C,d₂	Phosphatase FKBP Bacterial Autophagy Antibiotic	Infection Inflammation/Immunology Cancer
Tacrolimus- ¹³C,d₂ is a ¹³C-labeled and deuterium labeled Tacrolimus. Tacrolimus (FK506), a macrocyclic lactone, binds to FK506 binding protein (FKBP) to form a complex. Tacrolimus inhibits calcineurin phosphatase, which inhibits T-lymphocyte signal transduction and IL-2 transcription. Immunosuppressive properties[1].

HY-15005S

Sofosbuvir-13C,d3 PSI-7977-<sup>13sup>C,d₃; GS-7977-<sup>13sup>C,d₃	Isotope-Labeled Compounds HCV	Infection
Sofosbuvir- ¹³C,d₃ is the deuterium labeled Sofosbuvir. Sofosbuvir (PSI-7977) is an active inhibitor of HCV RNA replication in the HCV replicon assay, demonstrates potent anti-hepatitis C virus (HCV) activity.

HY-N1415S1

β-Caryophyllene-13C,d2 (-)-(E)-Caryophyllene-<sup>13sup>C,d₂; (−)-β-caryophyllene-<sup>13sup>C,d₂; (−)-trans-Caryophyllene-<sup>13sup>C,d₂	Endogenous Metabolite Cannabinoid Receptor Isotope-Labeled Compounds	Cancer
β-Caryophyllene- ¹³C,d₂ is ¹³C and deuterated labeled trans,trans-2,4-Decadienal (HY-W013627). trans,trans-2,4-Decadienal is a lipid peroxidation product of linolieic acid .

HY-N0098S

Vanillin-13C,d3 p-Vanillin-<sup>13sup>C,d₃; m-Methoxy-p-hydroxybenzaldehyde-<sup>13sup>C,d₃; p-Hydroxy-m-methoxybenzaldehyde-<sup>13sup>C,d₃	Endogenous Metabolite	Others
Vanillin- ¹³C,d₃ is the ¹³C and deuterium labeled Vanillin[1]. Vanillin (p-Vanillin) is a single molecule extracted from vanilla beans and also a popular odor used widely in perfume, food and medicine[2][3].

HY-W653977

Chlortetracycline-13C,d3 hydrochloride 7-Chlorotetracycline-<sup>13sup>C,d₃ hydrochloride	Isotope-Labeled Compounds Antibiotic Bacterial Parasite	Infection
Chlortetracycline-13C,d3 hydrochloride (7-Chlorotetracycline-13C,d3 hydrochloride) is the 13C- and deuterium labeled Chlortetracycline hydrochloride (HY-B1327). Chlortetracycline hydrochloride is an orally active, selective antibiotic, that inhibits methanogenic bacteria through inhibition of bacterial protein synthesis. Chlortetracycline hydrochloride is a specific and potent calcium ionophore antibiotic, that inhibits binding of aminoacyl-tRNA to ribosomes .

HY-16767S1

Doravirine-13C,d3 MK-1439-<sup>13sup>C,d₃	Isotope-Labeled Compounds HIV Reverse Transcriptase	Infection
Doravirine-13C,d3 (MK-1439-13C,d3) is the deuterium labeled Doravirine (HY-16767). Doravirine (MK-1439) is a highly specific HIV-1 nonnucleoside reverse transcriptase inhibitor with IC₅₀s of 4.5 nM, 5.5 nM and 6.1 nM against the wild type and K103N and Y181C reverse transcriptase mutants, respectively .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-128748

*DL-Glyceraldehyde*	Structural Classification Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Source classification Endogenous metabolite Saccharides Monosaccharides	Endogenous Metabolite
DL-Glyceraldehyde is a bioactive substance involved in cellular energy metabolism and a key intermediate in sugar metabolism pathways (such as glycolysis and gluconeogenesis). During glycolysis, DL-Glyceraldehyde is converted by enzymes into other metabolites to provide energy for cells; during gluconeogenesis, DL-Glyceraldehyde participates in the synthesis of glucose as a precursor. In the field of medical research, DL-Glyceraldehyde can be used to study diseases related to sugar metabolism, such as diabetes, tumors, etc[1][2].

HY-113054

DL-Glyceraldehyde 3-phosphate	Infection Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Acyltransferase Bacterial Endogenous Metabolite
DL-Glyceraldehyde 3-phosphate is an intermediate in several metabolic pathways, including glycolysis and gluconeogenesis. DL-Glyceraldehyde 3-phosphate is a potent inhibitor of the growth of *E. coli. DL-Glyceraldehyde* 3-phosphate is a competitive inhibitor of the acyltransferase .

HY-147089

PRRSV/CD163-IN-1	Infection Structural Classification Alkaloids Classification of Application Fields Other Alkaloids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Bacterial Endogenous Metabolite
PRRSV/CD163-IN-1 is a *PRRSV/CD163* inhibitor. PRRSV/CD163-IN-1 can inhibit the interaction between the PRRSV glycoprotein (GP2a or GP4) and the CD163-SRCR5 domain. PRRSV/CD163-IN-1 can be used for the research of porcine reproductive and respiratory syndrome (PRRS) .

HY-N3872

Ethyl β-D-glucopyranoside	Scabiosa stellata L. Structural Classification Natural Products Caprifoliaceae Source classification Plants	Others
Ethyl β-D-glucopyranoside (compound 10) is a kind of phenolic compound. Ethyl β-D-glucopyranoside can be isolated from ethanolic extract of Scabiosa stellata LS.

HY-N3980

Guaiol Champacol; Guaiac alcohol	Infection Structural Classification Natural Products Classification of Application Fields Source classification Distemonanthus benthamianus Baill. Plants Compositae Disease Research Fields	Autophagy RAD51
Guaiol is a sesquiterpenoid alcohol with oral activity found in various traditional Chinese medicines, exhibiting biological activities such as anti-proliferative, autophagy-promoting, insecticidal, anti-anxiety, anti-inflammatory, diuretic, and blood pressure-lowering effects. Guaiol induces apoptosis in non-small cell lung cancer cells by regulating the stability of RAD51 through autophagy modulation. Guaiol can also act directly on parasites, inhibiting their growth by affecting the kinetoplast, mitochondrial matrix and plasma membrane of the promastigotes. Guaiol kills amastigotes at an IC₅₀ of 0.01 µg/mL. Guaiol can be used in research related to cancer, infections, cardiovascular diseases, and inflammatory conditions ^{[4]sup .}

HY-N13288

Cordysinin C/D	Structural Classification Alkaloids Animals Other Alkaloids Source classification	Parasite
Cordysinin C/D (compound 9) is a potential anti-plasmodial compound that can effectively inhibit Plasmodium falciparum 3D7 strain .

HY-N12231

Carbazomycin B	Structural Classification Monophenols Microorganisms Source classification Phenols	Antibiotic Bacterial Lipoxygenase
Carbazomycin B is a bacterial metabolite and can be isolated from Streptomyces. Carbazomycin B is an antifungal and antibacterial agent. Carbazomycin B inhibits 5-lipoxygenase (5-LO) activity in extract from RBL-1 cell with the IC₅₀ Of 1.5 µM ^[1]sup>[2]sup>[3]sup>[4].

HY-N11122

7-[α-L-Arabinopyranosyl-(1→6)-β-D-glucopyranosyloxy]cuminol	Structural Classification Natural Products Rhodiola rosea Linn. Source classification Crassulaceae Plants	Others
7-[α-L-Arabinopyranosyl-(1→6)-β-D-glucopyranosyloxy]cuminol is a cuminol glycoside. 7-[α-L-Arabinopyranosyl-(1→6)-β-D-glucopyranosyloxy]cuminol can be isolated from Rhodiola rosea sup>[1].

HY-N8824

Maackiaflavanone	Structural Classification Flavonoids Leguminosae Flavonones Source classification Maackia amurensis Rupr. et Maxim. Plants	Others
Maackiaflavanone (compound 4) is a kind of prenylated flavanone. Maackia can be isolated from M. amurensi.

HY-N8859

Isoiridogermanal 16-Hydroxyiridal	Structural Classification Natural Products Source classification Lridaceae Plants	Others
Isoiridogermanal can be isolated from the extract of rhizomes of Iris tectorum Maxim. Isoiridogermanal is cytotoxic with IC50 values of 11 μM and 23 μM against MCF-7 and C32 cell lines.

HY-N8930

Eupatorin-5-methyl ether	Structural Classification Flavonoids Flavones Labiatae Source classification Plants Swartzia polyphylla DC.	Others
Eupatorin-5-methyl ether (TMF) can be isolated from Orthosiphon stamineus. Eupatorin-5-methyl ether is a kind of flavonoid compound. Eupatorin-5-methyl ether inhibits NO production (IC50 5.5 μM).

HY-N3980R

Guaiol (Standard)	Structural Classification Natural Products Source classification Distemonanthus benthamianus Baill. Plants Compositae	Autophagy RAD51
Guaiol (Standard) is the analytical standard of Guaiol. This product is intended for research and analytical applications. Guaiol is a sesquiterpenoid alcohol with oral activity found in various traditional Chinese medicines, exhibiting biological activities such as anti-proliferative, autophagy-promoting, insecticidal, anti-anxiety, anti-inflammatory, diuretic, and blood pressure-lowering effects. Guaiol induces apoptosis in non-small cell lung cancer cells by regulating the stability of RAD51 through autophagy modulation. Guaiol can also act directly on parasites, inhibiting their growth by affecting the kinetoplast, mitochondrial matrix and plasma membrane of the promastigotes. Guaiol kills amastigotes at an IC50 of 0.01 µg/mL. Guaiol can be used in research related to cancer, infections, cardiovascular diseases, and inflammatory conditions ^[3][4] .

HY-111054A

N-methyl-N-dithiocarboxyglucamine sodium MDCG sodium	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
N-methyl-N-dithiocarboxyglucamine (MDCG) sodium mobilizes and promotes excretion of metallothionein-bound ¹⁰⁹Cd in mouse model. N-methyl-N-dithiocarboxyglucamine significantly lowers the Cd content of both the liver and kidney, which is organs most susceptible to Cd-induced toxicity .

HY-B0579

Cyclosporin A Maximum Cited Publications 128 Publications Verification Cyclosporine A; Ciclosporin A; CsA	Structural Classification Natural Products Microorganisms Classification of Application Fields Anti-aging Source classification Inflammation/Immunology Disease Research Fields Cancer	Molecular Glues Complement System Antibiotic Cyclophilin
Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of protein phosphatase 2B (PP2B/calcineurin) with an IC₅₀ of 5 nM . Cyclosporin A also inhibits *CD11a/CD18* adhesion .

HY-111054

N-methyl-N-dithiocarboxyglucamine MDCG	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite
N-methyl-N-dithiocarboxyglucamine (MDCG) mobilizes and promotes excretion of metallothione-bound ¹⁰⁹Cd. N-methyl-N-dithiocarboxyglucamine shows effects on acute and chronic Cd intoxication .

HY-N10445

Maydispenoid A	Structural Classification Microorganisms Terpenoids Sesquiterpenes Source classification Plants Salicaceae	CD28 CD3
Maydispenoid A is a potent immunosuppressor. Maydispenoid A can inhibit anti-CD3/anti-CD28 mAbs activated and lipopolysaccharide activated murine splenocyte proliferation .

HY-W020790

Sialyl-Lewis X sLeX	Structural Classification Polysaccharides Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields Saccharides	Endogenous Metabolite
Sialyl-Lewis X (sLeX) is a sialylated fucosylated tetrasaccharide, an endogenous antigen. Sialyl-Lewis X is a high-affinity ligand for selectins (E-, P-, and L-selectin) . Sialyl-Lewis X binds to ELAM-1 and CD62 and has the ability?to inhibits CD62-mediated neutrophil recruitment to sites of inflammation .

HY-B0579R

Cyclosporin A (Standard)	Structural Classification Natural Products Microorganisms Source classification	Molecular Glues Complement System Antibiotic Cyclophilin
Cyclosporin A (Standard) is the analytical standard of Cyclosporin A. This product is intended for research and analytical applications. Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of protein phosphatase 2B (PP2B/calcineurin) with an IC50 of 5 nM . Cyclosporin A also inhibits CD11a/CD18 adhesion .

HY-N10446

Maydispenoid B	Structural Classification Microorganisms Terpenoids Sesquiterpenes Source classification	CD28 CD3
Maydispenoid B is a potent immunosuppressor. Maydispenoid B can inhibit anti-CD3/anti-CD28 mAbs activated and lipopolysaccharide activated murine splenocyte proliferation .

HY-B0430B

(±)-Pantothenic acid (±)-Pantothenate; (±)-Vitamin B5	Other disease Disease markers Endogenous metabolite	Endogenous Metabolite
(±)-Pantothenic acid ((±)-Pantothenate), a B-vitamin, is an essential vitamin required for the biosynthesis of coenzyme A (CoA) in mammalian cells. Pantothenic acid has protective activity against valproic acid (VPA)-induced neural tube defects (NTD) in CD-1 mice .

HY-N3829

epi-Eudesmol	Structural Classification Terpenoids Sesquiterpenes Source classification Erythrina burttii Baker f. Plants Compositae	Others
epi-Eudesmol is a Sesquiterpenoids product that can be isolated from the leaves of Laggera alata var. montana C. D. Adams. .

HY-N1115

Tubotaiwine (+)-Tubotaiwine; NSC 306222; Tubotaiwin	Apocynaceae Structural Classification Alkaloids Other Alkaloids Source classification Hunteria zeylanica Plants	Others
Tubotaiwine ((+)-Tubotaiwine), an alkaloid, has beneficial effect on cadmium (Cd) induced hypertension in rats. Tubotaiwine regulates systolic, diastolic and mean arterial blood pressure of the Cd exposed rats. Tubotaiwine reduces arterial stiffness, inhibits of oxidative stress and increases vascular remodeling .

HY-106784

Ajoene	Infection Structural Classification Natural Products Liliaceae Classification of Application Fields Source classification Plants Disease Research Fields A．Sativam L. var．Viviparum Regel	Fungal Apoptosis
Ajoene, a garlic-derived compound, is an antithrombotic and antifungal agent. Ajoene inhibits proliferation and induces apoptosis of human leukaemia CD34-negative cells including HL-60, U937, HEL and OCIM-I. Anticancer activities .

HY-B0134B

Bestatin trifluoroacetate Ubenimex trifluoroacetate	Infection Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields	Aminopeptidase Bacterial Antibiotic
Bestatin trifluoroacetate is an inhibitor of CD13 (Aminopeptidase N)/APN and leukotriene A4 hydrolase, used for cancer research.

HY-B0134A

Bestatin hydrochloride 5+ Cited Publications Ubenimex hydrochloride	Infection Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields	Aminopeptidase Bacterial Antibiotic
Bestatin hydrochloride is an inhibitor of CD13 (Aminopeptidase N)/APN and leukotriene A4 hydrolase, used for cancer research.

HY-B0134

Bestatin 5+ Cited Publications Ubenimex	Infection Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields	Aminopeptidase Bacterial Antibiotic
Bestatin is a natural, broad-spectrum, and competitive CD13 (Aminopeptidase N)/APN and leukotriene A4 hydrolase inhibitor. Bestatin has anticancer effects .

HY-N2362

DL-Alanine DL-2-Aminopropionic acid	Structural Classification Human Gut Microbiota Metabolites Classification of Application Fields Source classification Metabolic Disease Amino acids Endogenous metabolite Disease Research Fields	Endogenous Metabolite
DL-alanine, an orally active amino acid, is the racemic compound of L- and D-alanine. DL-alanine is employed both as a reducing and a capping agent, used with silver nitrate aqueous solutions for the production of nanoparticles. DL-alanine can be used for the research of transition metals chelation, such as Cu(II), Zn(II), Cd(11). DL-alanine, a sweetener, is classed together with glycine and sodium saccharin. DL-alanine plays a key role in the glucose-alanine cycle between tissues and liver .

HY-N10295

Flavipin	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Phenols Polyphenols Inflammation/Immunology Disease Research Fields	Aryl Hydrocarbon Receptor
Flavipin is an aryl hydrocarbon receptor (Ahr) agonist that induces the expression of Ahr downstream genes in mouse CD4 ⁺ T cells and CD11b ⁺ macrophages. Flavipin inhibits the stabilizing function of Arid5a on Il23a 3′UTR, a newly identified target mRNA . Flavipin exhibits the DPPH free radical scavenging ability with IC₅₀ value of 7.2 μM, and has potent α-glucosidase inhibition with IC₅₀ value of 33.8 μM .

HY-N2940

Bisandrographolide A BAA	Structural Classification Andrographis paniculata (Burm. F.) Nees Acanthaceae Terpenoids Source classification Diterpenoids Plants	TRP Channel
Bisandrographolide A (BAA) activates TRPV4 channel with an EC₅₀ of 790-950 nM. Bisandrographolide A can bind to CD81 and suppress its function. Bisandrographolide A is an anti-inflammatory, immunostimulant, and antihypertensive compound .

HY-N2109

Macranthoidin A	Triterpenes Structural Classification Caprifoliaceae Classification of Application Fields Terpenoids Source classification Metabolic Disease Plants Disease Research Fields	Others
Macranthoidin A is an orally active saponin from Flos Lonicerae. Macranthoidin A possess protection effects on hepatic injury caused by Acetaminophen, Cd, and CCl4, and conspicuous depressant effects on swelling of ear croton oil .

HY-N0640

Kuromanin chloride 5+ Cited Publications Chrysontemin; Cyanidin 3-O-glucoside chloride	Structural Classification Classification of Application Fields Source classification Metabolic Disease Plants Moraceae Anthocyans Flavonoids Microorganisms Phenols Polyphenols Disease Research Fields Morus alba Linn.	CD38
Kuromanin chloride (Chrysontemin) is derived from mulberry leaves and has the effect of increasing blood sugar concentration and maintaining lipid metabolism balance to reduce obesity. Kuromanin chloride can inhibit CD38 enzymatic activities .

HY-B0134R

Bestatin (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Aminopeptidase Bacterial Antibiotic
Bestatin (Standard) is the analytical standard of Bestatin. This product is intended for research and analytical applications. Bestatin is a natural, broad-spectrum, and competitive CD13 (Aminopeptidase N)/APN and leukotriene A4 hydrolase inhibitor. Bestatin has anticancer effects .

HY-N12613

Sydowimide A	Structural Classification Natural Products Microorganisms Marine natural products Source classification Marine microorganism	Phosphatase
Sydowimide A is a potent inhibitor of Src homology region 2 domain-containing phosphatase-1 (SHP1), T-cell protein tyrosine phosphatase (TCPTP) and leukocyte common antigen (CD45), with IC₅₀ values of 1.5, 2.4 and 18.83 μM, respectively .

HY-N2109R

Macranthoidin A (Standard)	Triterpenes Structural Classification Caprifoliaceae Terpenoids Source classification Plants	Others
Macranthoidin A (Standard) is the analytical standard of Macranthoidin A. This product is intended for research and analytical applications. Macranthoidin A is an orally active saponin from Flos Lonicerae. Macranthoidin A possess protection effects on hepatic injury caused by Acetaminophen, Cd, and CCl4, and conspicuous depressant effects on swelling of ear croton oil .

HY-N0640R

Kuromanin (chloride) (Standard)	Structural Classification Anthocyans Flavonoids Microorganisms Source classification Phenols Polyphenols Plants Moraceae Morus alba Linn.	CD38
Kuromanin (chloride) (Standard) is the analytical standard of Kuromanin (chloride). This product is intended for research and analytical applications. Kuromanin chloride (Chrysontemin) is derived from mulberry leaves and has the effect of increasing blood sugar concentration and maintaining lipid metabolism balance to reduce obesity. Kuromanin chloride can inhibit CD38 enzymatic activities .

HY-15310

Ivermectin 25+ Cited Publications MK-933; CD-5024; K-237	Structural Classification Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Antiviral Anti-parasitic Disease Research Disease Research Fields Cancer	Flavivirus Dengue Virus Parasite HIV Mitophagy HSV SARS-CoV Antibiotic Autophagy Bacterial
Ivermectin (MK-933) is a broad-spectrum anti-parasite agent. Ivermectin (MK-933) is a specific inhibitor of Impα/β1-mediated nuclear import and has potent antiviral activity towards both HIV-1 and dengue virus. It is a positive allosteric effector of P2X₄ and the α7 neuronal nicotinic acetylcholine receptor (nAChRs). Ivermectin also inhibits bovine herpesvirus1 (BoHV-1) replication and inhibits BoHV-1 DNA polymerase nuclear import . Ivermectin is a candidate therapeutic against SARS-CoV-2/COVID-19 .

HY-119347

Cirsilineol 3 Publications Verification	Laburnum anagyroides Medic. Structural Classification Monophenols Flavonoids Classification of Application Fields Flavones Source classification Phenols Plants Compositae Inflammation/Immunology Disease Research Fields	IFNAR STAT
Cirsilineol, a natural flavone compound, selectively inhibits IFN-γ/STAT1/T-bet signaling in intestinal CD4 ⁺ T cells. Cirsilineol has potent immunosuppressive and anti-tumor properties. Cirsilineol significantly ameliorates trinitro-benzene sulfonic acid (TNBS)-induced T-cell-mediated experimental colitis in mice .

HY-N9965

2'-Fucosyllactose 2'-FL	Infection Structural Classification Polysaccharides Animals Classification of Application Fields Inflammation/Immunology Disease Research Fields Saccharides	TNF Receptor Interleukin Related
2'-Fucosyllactose (2'-FL) is an oligosaccharide that could be derived from human milk. 2'-Fucosyllactose regulates the expression of CD14, alleviates colitis and regulates the gut microbiome. 2'-Fucosyllactose stimulates T cells to increase IFN-γ production and decreases IL-6, IL-17, and TNF-α production of cytokines .

HY-116003

12,13-DiHOME	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
12,13-DiHOME is a stimulator of Brown adipose tissue (BAT), as well as a thermogenic lipokine that activates BAT in response to cold. (±)12,13-DiHOME activates BAT fuel uptake and enhances cold tolerance, via promoting the translocation of the FA transporters FATP1 and CD36 to the cell membrane. (±)12,13-DiHOME can be used for research of metabolic disorders .

HY-N0743

Senkyunolide A 2 Publications Verification	Structural Classification Natural Products Classification of Application Fields Source classification Dicerothamnus rhinocerotis Umbelliferae Plants Disease Research Fields Cancer	α-synuclein
Senkyunolide A is a phthalide, anti-tumor cell proliferation agent with anticancer activity. Senkyunolide A protects neurons from corticosterone (HY-B1618)-induced apoptosis by decreasing protein phosphatase PP2A and α-synuclein phosphorylation and protein level. Senkyunolide A also inhibits osteoarthritis through the NLRP3 signaling pathway and suppresses the expression of *CD137*, a diagnostic biomarker for atherosclerosis .

HY-119347R

Cirsilineol (Standard)	Laburnum anagyroides Medic. Structural Classification Monophenols Flavonoids Flavones Source classification Phenols Plants Compositae	IFNAR STAT
Cirsilineol (Standard) is the analytical standard of Cirsilineol. This product is intended for research and analytical applications. Cirsilineol, a natural flavone compound, selectively inhibits IFN-γ/STAT1/T-bet signaling in intestinal CD4+ T cells. Cirsilineol has potent immunosuppressive and anti-tumor properties. Cirsilineol significantly ameliorates trinitro-benzene sulfonic acid (TNBS)-induced T-cell-mediated experimental colitis in mice .

HY-107780A

Cyclic-di-GMP sodium c-di-GMP sodium; cyclic diguanylate sodium; 5GP-5GP sodium	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	STING Endogenous Metabolite
Cyclic-di-GMP sodium is a STING agonist and a bacterial second messenger that coordinates different aspects of bacterial growth and behavior, including motility, virulence, biofilm formation, and cell cycle progression. Cyclic-di-GMP sodium has anti-cancer cell proliferation activity and also induces elevated CD4 receptor expression and cell cycle arrest. Cyclic-di-GMP sodium can be used in cancer research .

HY-107780

Cyclic-di-GMP c-di-GMP; cyclic diguanylate; 5GP-5GP	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	STING Endogenous Metabolite
Cyclic-di-GMP is a STING agonist and a bacterial second messenger that coordinates different aspects of bacterial growth and behavior, including motility, virulence, biofilm formation, and cell cycle progression. Cyclic-di-GMP has anti-cancer cell proliferation activity and also induces elevated CD4 receptor expression and cell cycle arrest. Cyclic-di-GMP can be used in cancer research .

HY-129997

Luteolinidin chloride	Structural Classification Anthocyans Flavonoids Sorghum bicolor (Linn.) Moench Classification of Application Fields Gramineae Source classification Phenols Polyphenols Plants Inflammation/Immunology Disease Research Fields	CD38 NADPH Oxidase Tyrosinase
Luteolinidin chloride is a deoxyanthocyanidin isolated from the plant Sorghum bicolor with antioxidant activity. Luteolinidin chloride is a potent *CD38* inhibitor (K_i=11.4 μM) and protects the heart from ischemia/reperfusion injury by preserving endothelial nitric oxide synthase (eNOS) function and preventing endothelial dysfunction. Luteolinidin chloride is also a competitive inhibitor of tyrosinase (IC₅₀=3.7 μM) and blocks the production of melanin .

HY-110382

Cyclic-di-GMP disodium 5+ Cited Publications c-di-GMP disodium; cyclic diguanylate disodium; 5GP-5GP disodium	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Cancer	STING Endogenous Metabolite
Cyclic-di-GMP disodium is a STING agonist and a bacterial second messenger that coordinates different aspects of bacterial growth and behavior, including motility, virulence, biofilm formation, and cell cycle progression. Cyclic-di-GMP disodium has anti-cancer cell proliferation activity and also induces elevated CD4 receptor expression and cell cycle arrest. Cyclic-di-GMP disodium can be used in cancer research .

HY-107780B

Cyclic-di-GMP diammonium 5+ Cited Publications c-di-GMP diammonium; cyclic diguanylate diammonium; 5GP-5GP diammonium	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	STING Endogenous Metabolite
Cyclic-di-GMP diammonium is a STING agonist and a bacterial second messenger that coordinates different aspects of bacterial growth and behavior, including motility, virulence, biofilm formation, and cell cycle progression. Cyclic-di-GMP diammonium has anti-cancer cell proliferation activity and also induces elevated CD4 receptor expression and cell cycle arrest. Cyclic-di-GMP diammonium can be used in cancer research .

HY-N9481

Lipoteichoic acid	Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Inflammation/Immunology Disease Research Fields	Complement System Autophagy mTOR Akt PI3K ERK Interleukin Related
Lipoteichoic acid is an orally effect anti-inflammatory and antitumor agent. Lipoteichoic acid is a crucial immune molecule in Gram-positive bacteria that activates the complement system by inducing C3 and inhibiting *CD55. Lipoteichoic acid regulates macrophage autophagy through the PI3K/Akt/mTOR* pathway. Lipoteichoic acid induces lung damage in mice. Lipoteichoic acid inhibits the production of melanin .

HY-N2199

Sotetsuflavone	Structural Classification Flavonoids Classification of Application Fields Source classification Phenols Polyphenols Selaginellaceae Plants Biflavones Selaginella tamariscina (P. Beauv.) Spring Disease Research Fields Cancer	Apoptosis Autophagy
Sotetsuflavone is a flavonoid that can be isolated from Cycas revolute. Sotetsuflavone inhibits migration and invasion of A549 cells by reversing EMT, and induces cell apoptosis and autophagy. Sotetsuflavone inhibits HIF-1α, VEGF, angiostatin, MMP-9, and MMP-13 expression in A549 cells. Sotetsuflavone also protects mice against Crohn's disease (CD)-like colitis. Sotetsuflavone can be used for research of NSCLC .

HY-N12537

PD-1/PD-L1-IN-38	Structural Classification Ketones, Aldehydes, Acids Labiatae Source classification Samanea saman (Jacq.) Merr. Plants	PD-1/PD-L1
PD-1/ PD-L1-in-38 is a PD-1/PD-L1 inhibitor, which can inhibit the proliferation of tumor cells, promote the secretion of INF-γ by CD8 ⁺ T cells, and inhibit the ability of PD-1/PD-L1 signal transduction. PD-1/PD-L1-IN-38 has antitumor activity .

HY-145491

Resolvin D5	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	ERK NF-κB
Resolvin D5 is a prolytic mediator (SPM) with anti-inflammatory activity derived from oxidized lipids DHA. Resolvin D5 inhibits Th17 cell differentiation and promotes regulatory T cell differentiation, and inhibits CD4+ T cell proliferation. Resolvin D5 attenuates osteoclast differentiation and interferes with osteoclastogenesis. Resolvin D5 also regulates ERK phosphorylation and nuclear translocation of NF-kappaB. Resolvin D5 could be used in rheumatoid arthritis research .

Cat. No.	Product Name	Chemical Structure

HY-10219S1

Rapamycin-13C,d3
Rapamycin- ¹³C,d₃ (Sirolimus- ¹³C,d₃; AY-22989- ¹³C,d₃) is the ¹³C and deuterium labeled Rapamycin (HY-10219) .Rapamycin is a potent and specific mTOR inhibitor with an IC₅₀ of 0.1 nM in HEK293 cells. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1. Rapamycin is an autophagy activator, an immunosuppressant .

HY-128748S2

DL-Glyceraldehyde-13C,d
DL-Glyceraldehyde- ¹³C,d is the deuterium and ¹³C labeled DL-Glyceraldehyde[1].

HY-128748S4

DL-Glyceraldehyde-13C3
DL-Glyceraldehyde- ¹³C₃ is the ¹³C labled DL-Glyceraldehyde (HY-128748) . DL-Glyceraldehyde is an organic compound.

HY-128748S

DL-Glyceraldehyde-1-13C
DL-Glyceraldehyde-1- ¹³C is the ¹³C labeled DL-Glyceraldehyde[1].

HY-128748S1

DL-Glyceraldehyde-2-13C
DL-Glyceraldehyde-2- ¹³C is the ¹³C labeled DL-Glyceraldehyde[1].

HY-165662S

Pranoprofen-13C-d3
Pranoprofen- ¹³C-d₃ (Pyaopofe- ¹³C-d₃) is ¹³C and deuterium labeled Pranoprofen .

HY-B0202S4

Irbesartan-13C,d4
Irbesartan- ¹³C,d₄ (SR-47436- ¹³C,d₄; BMS-186295- ¹³C,d₄) is ¹³C-labeled Irbesartan (HY-B0202) .

HY-B0389S19

D-Glucose-13C,d
D-Glucose- ¹³C,d is the deuterium and ¹³C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical sign

HY-13318S1

Oseltamivir acid-13C,d3
Oseltamivir acid-13C,d3 (GS 4071-13C,d3; Ro 64-0802-13C,d3) is a 13C- and deuterium-labeled Oseltamivir acid (HY-13318). Oseltamivir acid is the active metabolite of Oseltamivir phosphate and inhibits influenza virus neuraminidase (IC₅₀=2 nM). Oseltamivir acid is orally active and can be used to study influenza A/B infections .

HY-W011240S

Hydroflumethiazide-13C,d2
Hydroflumethiazide- ¹³C,d₂ is the deuterium and ¹³C labeled Hydroflumethiazide[1].

HY-N0378S6

D-Mannitol-13C,d2
D-Mannitol- ¹³C,d₂ is the deuterium and ¹³C labeled D-Mannitol.

HY-B0002BS2

Ondansetron-13C,d3
Ondansetron- ¹³C,d₃ is the ¹³C- and deuterium labeled Ondansetron[1].

HY-15651S

Alvelestat-13C,d3
Alvelestat- ¹³C,d₃ (AZD9668- ¹³C,d₃) is ¹³C-labeled Alvelestat (HY-15651) .

HY-W754842

Saxagliptin-13C,d2-1 hydrochloride
Saxagliptin- ¹³C,d₂-1 (BMS-477118- ¹³C,d₂) hydrochloride is ¹³C and deuterium labeled Saxagliptin (hydrochloride) .

HY-17413S1

Zidovudine-13C,d3

Zidovudine- ¹³C,d₃ is the ¹³C- and deuterium labeled Zidovudine. Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection. Zidovudine increases CRISPR/Cas9-mediated editing frequency. Zidovudine-13C,d3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-13693S2

Mometasone furoate-13C,d6
Mometasone furoate- ¹³C,d₆ (Sch32088- ¹³C,d₆) is ¹³C-labeled Mometasone furoate (HY-13693) .

HY-B0330S2

Levofloxacin-13C,d3
Levofloxacin- ¹³C,d₃ is the ¹³C- and deuterium labeled Levofloxacin.

HY-125818S2

Cytidine-5'-triphosphate-13C,d1 dilithium

Cytidine-5'-triphosphate- ¹³C,d₁ (Cytidine triphosphate- ¹³C,d₁ dilithium; 5'-CTP- ¹³C,d₁) dilithium is deuterium and ¹³C-labeled Cytidine-5'-triphosphate (HY-125818). Cytidine 5′-triphosphate (Cytidine triphosphate; 5'-CTP) is a nucleoside triphosphate and serves as a building block for nucleotides and nucleic acids, lipid biosynthesis. Cytidine triphosphate synthase can catalyze the formation of cytidine 5′-triphosphate from uridine 5′-triphosphate (UTP). Cytidine 5′-triphosphate is an essential biomolecule?in the de novo?pyrimidine biosynthetic pathway in?T. gondii.

HY-W777599

(±)-Naproxen-13C,d3-1
(±)-Naproxen- ¹³C,d₃-1 ((Rac)-Naproxen- ¹³C,d₃-1) is ¹³C and deuterium labeled (±)-Naproxen .

HY-121259S

Doxorubicinol-13C,d3 TFA
Doxorubicinol- ¹³C,d₃ (TFA) is the deuterium and ¹³C labeled Doxorubicinol TFA[1].

HY-13683S1

Mifepristone-13C,d3

Mifepristone- ¹³C,d₃ is the ¹³C- and deuterium labeled Mifepristone. Mifepristone (RU486) is a progesterone receptor (PR) and glucocorticoid receptor (GR) antagonist with IC50s of 0.2 nM and 2.6 nM in in vitro assay[1]. Mifepristone-13C,d3 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-B0389S25

D-Glucose-13C,d1
D-Glucose- ¹³C,d is the deuterium and ¹³C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical sig

HY-G0007S1

Omeprazole sulfone-13C,d3
Omeprazole metabolite Omeprazole sulfone- ¹³C,d₃ is the deuterium and ¹³C labeled Omeprazole metabolite Omeprazole sulfone[1].

HY-B0740S1

Cyclobenzaprine-13C,d3 hydrochloride
Cyclobenzaprine- ¹³C,d₃ (hydrochloride) is the ¹³C- and deuterium labeled Cyclobenzaprine (hydrochloride).

HY-B0192S1

Alfuzosin-13C,d3
Alfuzosin- ¹³C,d₃ is the ¹³C- and deuterium labeled Alfuzosin.

HY-18252S

Avanafil-13C,d3
Avanafil- ¹³C,d₃ is the ¹³C- and deuterium labeled Avanafil.

HY-B0389S21

D-Glucose-13C,d2
D-Glucose- ¹³C,d₂ is the deuterium and ¹³C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical sig

HY-111772S

Elexacaftor-13C,d3
Elexacaftor- ¹³C,d₃ is the deuterium labeled Elexacaftor (HY-111772)[1].

HY-B0621S1

Triclabendazole-13C,d3
Triclabendazole- ¹³C,d₃ is the ¹³C- and deuterium labeled Triclabendazole[1].

HY-17506S1

Azithromycin-13C,d3
Azithromycin- ¹³C,d₃ is the deuterium and ¹³C labeled Azithromycin[1].

HY-B0457S2

Clomipramine-13C,d3 hydrochloride
Clomipramine- ¹³C,d₃ (hydrochloride) is the ¹³C- and deuterium labeled Clomipramine (hydrochloride). Clomipramine (Chlorimipramine) hydrochloride is a potent 5-HT reuptake blocker with the IC50 value of 1.5 nM. Clomipramine hydrochloride is a tricyclic antidepressant that can be used for the research of depression and obsessive compulsive disorder (OCD)[1].

HY-14855S

Tedizolid-13C,d3
Tedizolid- ¹³C,d₃ is the ¹³C- and deuterium labeled Tedizolid. Tedizolid (TR 700; Torezolid; DA-7157) is a novel oxazolidinone, acting through inhibition of bacterial protein synthesis by binding to 23S ribosomal RNA (rRNA) of the 50S subunit of the ribosome.

HY-A0023AS

Alogliptin-13C,d3
Alogliptin- ¹³C,d₃ is the deuterium labeled Alogliptin. Alogliptin is a potent and selective inhibitor of DPP-4.

HY-90001S1

Ritonavir-13C,d3
Ritonavir- ¹³C,d₃ is the ¹³C- and deuterium labeled Ritonavir. Ritonavir (ABT 538) is an inhibitor of HIV protease used to treat HIV infection and AIDS. Ritonavir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 1.61 μM.

HY-10284S1

Linagliptin-13C,d3
Linagliptin- ¹³C,d₃ is the ¹³C- and deuterium labeled Linagliptin. Linagliptin is a highly potent, selective DPP-4 inhibitor with IC50 of 1 nM. Linagliptin-13C,d3 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-B0596S

Taltirelin-13C,d3
Taltirelin- ¹³C,d₃ (TA-0910- ¹³C,d₃) is ¹³C and deuterated labeled Taltirelin (HY-B0596). Taltirelin (TA0910) is a superagonist at thyrotropin-releasing hormone receptor (TRH-R) with an IC₅₀ of 910 nM and EC₅₀ of 36 nM for stimulating an increase in cytosolic Ca ²⁺ concentration (Ca ²⁺ release).

HY-10285S1

(rel)-Saxagliptin-13C,d2 TFA
(rel)-Saxagliptin- ¹³C,d₂ ((rel)-BMS-477118- ¹³C,d₂) TFA is ¹³C-labeled Saxagliptin (HY-10285) .

HY-10250S

Triciribine phosphate-13C,d3
Triciribine phosphate-- ¹³C,d₃ is the deuterium and ¹³C labeled Triciribine phosphate[1].

HY-66011AS4

Moxifloxacin-13C,d3 hydrochloride
Moxifloxacin- ¹³C,d₃ hydrochloride (BAY 12-8039- ¹³C,d₃) is ¹³C and deuterated labeled Moxifloxacin (HY-66011A). Moxifloxacin is an orally active 8-methoxyquinolone antimicrobial for use in the treatment of acute bacterial sinusitis, acute bacterial exacerbations of chronic bronchitis, and community-acquired pneumonia.

HY-126857AS1

5-Hydroxyomeprazole-13C,d2 sodium
5-Hydroxyomeprazole- ¹³C,d₂ sodium is ¹³C and deuterated labeled 5-Hydroxyomeprazole sodium (HY-126857A).

HY-13756S

Tacrolimus-13C,d2
Tacrolimus- ¹³C,d₂ is a ¹³C-labeled and deuterium labeled Tacrolimus. Tacrolimus (FK506), a macrocyclic lactone, binds to FK506 binding protein (FKBP) to form a complex. Tacrolimus inhibits calcineurin phosphatase, which inhibits T-lymphocyte signal transduction and IL-2 transcription. Immunosuppressive properties[1].

HY-15005S

Sofosbuvir-13C,d3
Sofosbuvir- ¹³C,d₃ is the deuterium labeled Sofosbuvir. Sofosbuvir (PSI-7977) is an active inhibitor of HCV RNA replication in the HCV replicon assay, demonstrates potent anti-hepatitis C virus (HCV) activity.

HY-N1415S1

β-Caryophyllene-13C,d2
β-Caryophyllene- ¹³C,d₂ is ¹³C and deuterated labeled trans,trans-2,4-Decadienal (HY-W013627). trans,trans-2,4-Decadienal is a lipid peroxidation product of linolieic acid .

HY-N0098S

Vanillin-13C,d3
Vanillin- ¹³C,d₃ is the ¹³C and deuterium labeled Vanillin[1]. Vanillin (p-Vanillin) is a single molecule extracted from vanilla beans and also a popular odor used widely in perfume, food and medicine[2][3].

HY-W653977

Chlortetracycline-13C,d3 hydrochloride

Chlortetracycline-13C,d3 hydrochloride (7-Chlorotetracycline-13C,d3 hydrochloride) is the 13C- and deuterium labeled Chlortetracycline hydrochloride (HY-B1327). Chlortetracycline hydrochloride is an orally active, selective antibiotic, that inhibits methanogenic bacteria through inhibition of bacterial protein synthesis. Chlortetracycline hydrochloride is a specific and potent calcium ionophore antibiotic, that inhibits binding of aminoacyl-tRNA to ribosomes .

HY-16767S1

Doravirine-13C,d3
Doravirine-13C,d3 (MK-1439-13C,d3) is the deuterium labeled Doravirine (HY-16767). Doravirine (MK-1439) is a highly specific HIV-1 nonnucleoside reverse transcriptase inhibitor with IC₅₀s of 4.5 nM, 5.5 nM and 6.1 nM against the wild type and K103N and Y181C reverse transcriptase mutants, respectively .

HY-10159S1

Nilotinib-13C,d3
Nilotinib-13C,d3 is a deuterated labeled Nilotinib . Nilotinib is an orally available Bcr-Abl tyrosine kinase inhibitor with antineoplastic activity.

HY-100427S

Imazamox-13C,d3
Imazamox- ¹³C,d₃ is the ¹³C- and deuterium labeled Imazamox. Imazamox (CL29926) is a systemic herbicide that inhibits the production of acetolactate synthase (ALS) in plants with high selectivity, high activity, safety and broadspectrum activity, which would then inhibit plant growth and ultimately lead to plant death[1][2].

HY-15772S1

Osimertinib-13C,d3
Osimertinib- ¹³C,d₃ is the deuterium and ¹³C labeled Osimertinib. Osimertinib (AZD9291) is a covalent, orally active, irreversible, and mutant-selective EGFR inhibitor with an apparent IC50 of 12 nM against L858R and 1 nM against L858R/T790M, respectively.

HY-16106S

Talazoparib-13C,d4
Talazoparib- ¹³C,d4 is ¹³C and deuterated labeled Talazoparib (HY-16106). Talazoparib is an orally active PARP 1/2 inhibitor with Ki values of 1.2 nM and 0.87 nM for inhibiting PARP1 and PARP2 enzymatic activities, respectively. Has anti-tumor activity.

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Species:	Human (1222) Rhesus Macaque/Cynomolgus (1) Marmoset (2) Rhesus Macaque (143) Mouse (466) Rat (216) Cynomolgus (240) E.coli (2) Rabbit (12) Dog (1) Canine (49) Pig (1)
Tag:	SUMO (17) GST (21) Flag (45) GFP (1) His (1546) Tag Free (89) Strep (2) Avi (386) Myc (15) HSA (1) MBP (1) Trx (4) Fc (735) B2M (1)
Source:	HEK293 (2156) E. coli Cell-free (7) CHO (6) CHO (9) Sf9 insect cells (3) P. pastoris (20) Sf9 insect cells (50) E. coli (83)


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