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H<sup> </sup> pump

" in MedChemExpress (MCE) Product Catalog:

4349

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11

Screening Libraries

49

Fluorescent Dye

160

Biochemical Assay Reagents

637

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2

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60

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480

Natural
Products

880

Recombinant Proteins

1059

Isotope-Labeled Compounds

172

Antibodies

67

Click Chemistry

238

Oligonucleotides

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-15306S
    Eltrombopag-13C4
    1 Publications Verification

    SB-497115-<sup>13sup>C4

    		 Thrombopoietin Receptor Bacterial Apoptosis Infection Cardiovascular Disease Cancer
    Eltrombopag- 13C4 (SB-497115- 13C4) is 13 sup>C-labeled Z-Eltrombopag. Z-Eltrombopag is an orally active thrombopoietin-receptor non-peptide agonist with platelet-stimulating activity for the study of chronic immune thrombocytopenia. Eltrombopag also has strong inhibitory effects on multidrug-resistant Staphylococcus aureus (Staphylococcus aureus) and can induce apoptosis (apoptosis) in liver cancer cells .
    Eltrombopag-13C4
  • HY-126906
    Milbemycin A4

    		Antibiotic P-glycoprotein Cancer
    Milbemycin A4 inhibits P-glycoprotein activity, and reverses multidrug resistance of tumor cells. Milbemycins are a family of macrolide antibiotics with insecticidal and acaricidal activity [1]sup>[2].
    Milbemycin A4
  • HY-B0113S3
    Omeprazole-13CD3

    H 16868-<sup>13sup>C,d3

    		 Proton Pump Autophagy Bacterial Phospholipase Infection Metabolic Disease Cancer
    Omeprazole- 13C,d3 is a 13C-labeled and deuterium labeled Omeprazole. Omeprazole (H 16868), a proton pump inhibitor (PPI), is available for treatment of acid-related gastrointestinal disorders. Omeprazole shows competitive inhibition of CYP2C19 activity with a Ki of 2 to 6 μM[1]. Omeprazole also inhibits growth of Gram-positive and Gram-negative bacteria[2].Omeprazole is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor)[3].
    Omeprazole-13CD3
  • HY-W011509
    CyPPA

    		Potassium Channel Neurological Disease
    CyPPA is a positive modulator of hSK3 and hSK2, with EC50 values of 14 μM and 5.6 μM, repectively. CyPPA is inactive on both hSK1 and hIK channels [1]sup .
    CyPPA
  • HY-W014423S
    L-Histidine-13C hydrochloride hydrate

    H-His-OH-<sup>13sup>C hydrochloride hydrate

    		 Endogenous Metabolite Metabolic Disease
    L-Histidine- 13C (hydrochloride hydrate) is the 13C-labeled L-Histidine hydrochloride hydrate. L-Histidine hydrochloride hydrate (H-His-OH.HCl.H2O) is an endogenous metabolite.
    L-Histidine-13C hydrochloride hydrate
  • HY-W014423S6
    L-Histidine-15N hydrochloride hydrate

    H-His-OH-<sup>15sup>N hydrochloride hydrate

    		 Isotope-Labeled Compounds Endogenous Metabolite Metabolic Disease
    L-Histidine- 15N (hydrochloride hydrate) is the 15N-labeled L-Histidine hydrochloride hydrate. L-Histidine hydrochloride hydrate (H-His-OH.HCl.H2O) is an endogenous metabolite.
    L-Histidine-15N hydrochloride hydrate
  • HY-N12231
    Carbazomycin B

    		Antibiotic Bacterial Lipoxygenase Infection Cancer
    Carbazomycin B is a bacterial metabolite and can be isolated from Streptomyces. Carbazomycin B is an antifungal and antibacterial agent. Carbazomycin B inhibits 5-lipoxygenase (5-LO) activity in extract from RBL-1 cell with the IC50 Of 1.5 µM [1]sup>[2]sup>[3]sup>[4].
    Carbazomycin B
  • HY-108166
    Hydroxystilbamidine

    		Fluorescent Dye Inflammation/Immunology
    Hydroxystilbamidine, a dye capable of binding to both DNA and RNA, is a powerful inhibitor of cellular ribonucleases. Hydroxystilbamidine is a retrograde fluorescent tracer and a histochemical stain [1]sup .
    Hydroxystilbamidine
  • HY-145128
    GR103545

    		Opioid Receptor Neurological Disease
    GR103545 is a potent and selective agonist of the κ-opioid receptor (κ-OR). 11GR103545 is a radiotracer for imaging κ-OR in vivo [1]sup .
    GR103545
  • HY-N11122
    7-[α-L-Arabinopyranosyl-(1→6)-β-D-glucopyranosyloxy]cuminol

    		Others Others
    7-[α-L-Arabinopyranosyl-(1→6)-β-D-glucopyranosyloxy]cuminol is a cuminol glycoside. 7-[α-L-Arabinopyranosyl-(1→6)-β-D-glucopyranosyloxy]cuminol can be isolated from Rhodiola rosea sup>[1].
    7-[α-L-Arabinopyranosyl-(1→6)-β-D-glucopyranosyloxy]cuminol
  • HY-161119
    Drpitor1a

    		Dynamin Reactive Oxygen Species Cardiovascular Disease Cancer
    Drpitor1a is a potent Drp1 inhibitor. Drpitor1a inhibits mitochondrial ROS production, preventes mitochondrial fission, and improves right ventricular diastolic dysfunction during IR (ischemia reperfusion) injury. Drpitor1a has the potential for the research of lung cancer [1]sup .
    Drpitor1a
  • HY-126906R
    Milbemycin A4 (Standard)

    		Antibiotic P-glycoprotein Cancer
    Milbemycin A4 (Standard) is the analytical standard of Milbemycin A4. This product is intended for research and analytical applications. Milbemycin A4 inhibits P-glycoprotein activity, and reverses multidrug resistance of tumor cells. Milbemycins are a family of macrolide antibiotics with insecticidal and acaricidal activity [1]sup> .
    Milbemycin A4 (Standard)
  • HY-W014423S3
    L-Histidine-13C6,15N3 hydrochloride hydrate

    H-His-OH-<sup>13sup>C6,<sup>15sup>N3 hydrochloride hydrate

    		 Isotope-Labeled Compounds Endogenous Metabolite Metabolic Disease
    L-Histidine- 13C6, 15N3 (hydrochloride hydrate) is the 13C- and 15N-labeled L-Histidine hydrochloride hydrate. L-Histidine hydrochloride hydrate (H-His-OH.HCl.H2O) is an endogenous metabolite.
    L-Histidine-13C6,15N3 hydrochloride hydrate
  • HY-W014423S2
    L-Histidine-13C6 hydrochloride hydrate

    H-His-OH-<sup>13sup>C6 hydrochloride hydrate

    		 Endogenous Metabolite Metabolic Disease
    L-Histidine- 13C6 (hydrochloride hydrate) is the 13C-labeled L-Histidine hydrochloride hydrate. L-Histidine hydrochloride hydrate (H-His-OH.HCl.H2O) is an endogenous metabolite.
    L-Histidine-13C6 hydrochloride hydrate
  • HY-W014423S5
    L-Histidine-15N3 hydrochloride hydrate

    H-His-OH-<sup>15sup>N3 hydrochloride hydrate

    		 Isotope-Labeled Compounds Endogenous Metabolite Metabolic Disease
    L-Histidine- 15N3 (hydrochloride hydrate) is the 15N-labeled L-Histidine hydrochloride hydrate. L-Histidine hydrochloride hydrate (H-His-OH.HCl.H2O) is an endogenous metabolite.
    L-Histidine-15N3 hydrochloride hydrate
  • HY-12741
    LDN-212320
    5 Publications Verification

    LDN-0212320; OSU-0212320

    		 EAAT Neurological Disease
    LDN-212320 (LDN-0212320) is a glutamate transporter (GLT-1)/excitatory amino acid transporter 2 (EAAT2) activator (at translational level). LDN-212320 (LDN-0212320) prevents nociceptive pain by upregulating astroglial GLT-1 expression in the hippocampus and ACC [1]sup .
    LDN-212320
  • HY-B0656S1
    Rabeprazole-13C,d3

    LY307640-<sup>13sup>C,d3

    		 Isotope-Labeled Compounds Proton Pump Bacterial Apoptosis Cancer
    Rabeprazole-13C,d3 is a deuterated labeled Rabeprazole . Rabeprazole (LY307640) is a second-generation proton pump inhibitor (PPI) that irreversibly inactivates gastric H +/K +-ATPase. Rabeprazole induces apoptosis. Rabeprazole acts as an uridine nucleoside ribohydrolase (UNH) inhibitor with an IC50 of 0.3 μM. Rabeprazole can be used for the research of gastric ulcerations and gastroesophageal reflux .
    Rabeprazole-13C,d3
  • HY-N8824
    Maackiaflavanone

    		Others Others
    Maackiaflavanone (compound 4) is a kind of prenylated flavanone. Maackia can be isolated from M. amurensi.
    Maackiaflavanone
  • HY-Y1250S6
    Fmoc-Gly-OH-13C2,15N

    Fmoc glycine-<sup>13sup>C2,<sup>15sup>N; N-(9-Fluorenylmethoxycarbonyl)glycine-<sup>13sup>C2,<sup>15sup>N; N-Fluorenylmethoxycarbonylglycine-<sup>13sup>C2,<sup>15sup>N; NPC 14692-<sup>13sup>C2-<sup>15sup>N; NSC 334288-<sup>13sup>C2,<sup>15sup>N; [[[(9H-Fluoren-9-yl)methoxy]carbonyl]amino]acetic acid-<sup>13sup>C2,<sup>15sup>N

    		 Isotope-Labeled Compounds Influenza Virus Bacterial Infection
    Fmoc-Gly-OH- 13C2, 15N is a 15N-labeled and 13C-labled Crystal Violet. Crystal violet (Basic Violet 3) is a triarylmethane dye. Crystal Violet (Gentian Violet) has antiviral effects against H1N1 and also has prominent bactericidal activities.
    Fmoc-Gly-OH-13C2,15N
  • HY-E70131
    Endo H, Streptomyces picatus

    Endo-β-N-acetylglucosaminidase H

    		 Others Metabolic Disease
    Endo H, Streptomyces picatus (Endo-β-N-acetylglucosaminidase H), isolated from Streptomyces plicatus, hydrolyzes the central glycosidic bond of the β1, 4-di-N-acetylchitobiose core in asparagine-linked oligosaccharides .
    Endo H, Streptomyces picatus
  • HY-131846
    6-Cl-5'-PuMP

    6-Chloropurine 5'-ribonucleotide

    		 Others Others
    6-Cl-5'-PuMP is a reactive analogue of adenosine 5’-O-monophosphate (5’-AMP), and is suitable for modifying position 6 using various nucleophiles .
    6-Cl-5'-PuMP
  • HY-Y0850U
    PVA (Mw 31000, 87-89% hydrolyzed, ～630 polymerization)

    Polyvinyl alcohol (Mw 31000, 87-89% hydrolyzed, ～630 polymerization); Poly(Ethenol) (Mw 31000, 87-89% hydrolyzed, ～630 polymerization)

    		 Biochemical Assay Reagents Others
    PVA (Mw 31000, 87-89% hydrolyzed, ～630 polymerization) (Polyvinyl alcohol (Mw 31000, 87-89% hydrolyzed, ～630 polymerization); Poly(Ethenol) (Mw 31000, 87-89% hydrolyzed, ～630 polymerization)) is a biocompatible, biodegradable, nontoxic and hydrophilic synthetic polymer. PVA (Mw 31000, 87-89% hydrolyzed, ～630 polymerization) can be used to produce bone tissue engineering scaffold [1]sup .
    PVA (Mw 31000, 87-89% hydrolyzed, ～630 polymerization)
  • HY-W014423S1
    L-Histidine-13C6,15N3,d5 hydrochloride hydrate

    H-His-OH-<sup>13sup>C6,<sup>15sup>N3,d5 hydrochloride hydrate

    		 Isotope-Labeled Compounds Endogenous Metabolite Metabolic Disease
    L-Histidine- 13C6, 15N3,d5 (hydrochloride hydrate) is the deuterium, 13C-, and 15-labeled L-Histidine hydrochloride hydrate. L-Histidine hydrochloride hydrate (H-His-OH.HCl.H2O) is an endogenous metabolite.
    L-Histidine-13C6,15N3,d5 hydrochloride hydrate
  • HY-B2176S
    ATP-13C10,15N5

    Adenosine 5'-triphosphate-<sup>13sup>C10,<sup>15sup>N5

    		 Endogenous Metabolite Metabolic Disease
    ATP- 13C10, 15N5 is the 13C and 15N labeled ATP[1]. ATP (Adenosine 5'-triphosphate) is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation[2][3].
    ATP-13C10,15N5
  • HY-W103287
    2-Hydroxyisoquinoline-1,3(2H,4H)-dione

    		HIV Integrase Infection
    Hydroxyisoquinoline-1,3(2H,4H)-dione (compound 6a) is a HIV-1 integrase (IN) and HIV-1 reverse transcriptase (RT) ribonuclease H (RNase H) inhibitor with an IC50 value of 6.32, 5.9 µM, respectively .
    2-Hydroxyisoquinoline-1,3(2H,4H)-dione
  • HY-B2176S2
    ATP-13C dilithium

    Adenosine 5'-triphosphate-<sup>13sup>C dilithium

    		 Isotope-Labeled Compounds Endogenous Metabolite Metabolic Disease Inflammation/Immunology
    ATP- 13C (Adenosine 5'-triphosphate- 13C) dilithium is 13C-labeled ATP (HY-B2176). ATP (Adenosine 5'-triphosphate) is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation.
    ATP-13C dilithium
  • HY-N0091S2
    Hypoxanthine-13C5

    Purin-6-ol-<sup>13sup>C5; Sarcine-<sup>13sup>C5

    		 Endogenous Metabolite Isotope-Labeled Compounds Others
    Hypoxanthine- 13C5 is a 13C-labeled H-Lys-OH.2HCl[1].
    Hypoxanthine-13C5
  • HY-E70228
    Cathepsin H, human liver

    		Others Cancer
    Cathepsin H, human liver is an aminopeptidase and an endopeptidase. Involved in the catabolism of proteins in the lysosomal system. Cathepsin H, human liver has a key role in the regulation of the biological behavior of tumor cells and the pathological processes of brain diseases .
    Cathepsin H, human liver
  • HY-N3872
    Ethyl β-D-glucopyranoside

    		Others Others
    Ethyl β-D-glucopyranoside (compound 10) is a kind of phenolic compound. Ethyl β-D-glucopyranoside can be isolated from ethanolic extract of Scabiosa stellata LS.
    Ethyl β-D-glucopyranoside
  • HY-101664
    Ilaprazole

    IY-81149

    		 Proton Pump TOPK Inflammation/Immunology Cancer
    Ilaprazole (IY-81149) is an orally active proton pump inhibitor. Ilaprazole irreversibly inhibits H +/K +-ATPase in a dose-dependent manner with an IC50 of pump inhibitory activity of 6 μM in rabbit parietal cell preparation. Ilaprazole is used for the research of gastric ulcers. Ilaprazole is also a potent TOPK (T-lymphokine-activated killer cell-originated protein kinase) inhibitor .
    Ilaprazole
  • HY-B2176S6
    ATP-13C10 dilithium

    Adenosine 5'-triphosphate-<sup>13sup>C10 dilithium

    		 Isotope-Labeled Compounds Endogenous Metabolite Metabolic Disease Inflammation/Immunology
    ATP- 13C10 (Adenosine 5'-triphosphate- 13C10) dilithium is 13C-labeled ATP (HY-B2176). ATP (Adenosine 5'-triphosphate) is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation.
    ATP-13C10 dilithium
  • HY-B2176S5
    ATP-15N5 dilithium

    Adenosine 5'-triphosphate-<sup>15sup>N5 dilithium

    		 Isotope-Labeled Compounds Endogenous Metabolite Metabolic Disease Inflammation/Immunology
    ATP- 15N5 (Adenosine 5'-triphosphate- 15N5) dilithium is 15N labeled ATP (HY-B2176). ATP (Adenosine 5'-triphosphate) is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation.
    ATP-15N5 dilithium
  • HY-D1583
    Cyanine5 DBCO
    1 Publications Verification

    DBCO-Cy5; Cyanine5 dibenzocyclooctyne

    		 Fluorescent Dye Others
    Cyanine5 DBCO (DBCO-Cy5) is a low-toxicity azide reactive probe (NIR fluorescent dye), for imaging azide-labeled biomolecules via a copper-free "click-through" reaction. Cyanine5 DBCO has no apparent cytotoxicity or animal toxicity and shows no damage to the physiological functions of cells other than the target cells (azide-labeled cells). Cyanine5 DBCO can be used to label and track cells in vitro and in vivo (Ex=635 nm, Em=650-700 nm) [2].
    Cyanine5 DBCO
  • HY-N8859
    Isoiridogermanal

    16-Hydroxyiridal

    		 Others Others
    Isoiridogermanal can be isolated from the extract of rhizomes of Iris tectorum Maxim. Isoiridogermanal is cytotoxic with IC50 values of 11 μM and 23 μM against MCF-7 and C32 cell lines.
    Isoiridogermanal
  • HY-163473
    IITR08367

    		Bacterial Infection
    IITR08367 is a potent effector pump Acinetobacter baumannii Fosfomycin Efflux pump (AbaF) inhibitor for enhancing the antimicrobial activity of Fosfomycin (HY-B1075A) against Acinetobacter baumannii. IITR08367 acts by interfering with Fosfomycin/H + reverse transporter activity. .
    IITR08367
  • HY-156383
    SCO-PEG3-NHS

    		PROTAC Linkers Cancer
    SCO-PEG3-NHS is a PEG linker with a terminal imine(NH) group. SCO-PEG3-NHS is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
    SCO-PEG3-NHS
  • HY-101664R
    Ilaprazole (Standard)

    		Proton Pump TOPK Inflammation/Immunology Cancer
    Ilaprazole (Standard) is the analytical standard of Ilaprazole. This product is intended for research and analytical applications. Ilaprazole (IY-81149) is an orally active proton pump inhibitor. Ilaprazole irreversibly inhibits H +/K +-ATPase in a dose-dependent manner with an IC50 of pump inhibitory activity of 6 μM in rabbit parietal cell preparation. Ilaprazole is used for the research of gastric ulcers. Ilaprazole is also a potent TOPK (T-lymphokine-activated killer cell-originated protein kinase) inhibitor .
    Ilaprazole (Standard)
  • HY-13662S
    Lansoprazole-d4

    AG-1749-d4

    		 Proton Pump Bacterial Inflammation/Immunology Cancer
    Lansoprazole-d4 is a deuterium labeled Lansoprazole. Lansoprazole is a proton pump inhibitor which prevents the stomach from producing acid[1].
    Lansoprazole-d4
  • HY-109079A
    Abeprazan hydrochloride

    DWP14012 hydrochloride; Fexuprazan hydrochloride

    		 Proton Pump Metabolic Disease
    Abeprazan hydrochloride (DWP14012 hydrochloride) is a potassium-competitive acid blocker. Abeprazan hydrochloride inhibits H +, K +- ATPase by reversible potassium-competitive ionic binding with no acid activation required. Abeprazan hydrochloride is developed as a potential alternative to proton pump inhibitor for the treatment of acid-related diseases .
    Abeprazan hydrochloride
  • HY-109079
    Abeprazan

    DWP14012; Fexuprazan

    		 Proton Pump Metabolic Disease
    Abeprazan (DWP14012) is a potassium-competitive acid blocker. Abeprazan inhibits H +, K +- ATPase by reversible potassium-competitive ionic binding with no acid activation required. Abeprazan is developed as a potential alternative to proton pump inhibitor for the treatment of acid-related diseases .
    Abeprazan
  • HY-D1327
    Cyanine3 azide chloride

    		Fluorescent Dye Others
    Cyanine3 azide chloride, an analog of Cy3 azide, is a potent green fluorescent dye. Cyanine3 azide chloride uses click chemistry coupled with Alkyne-labeled proteins. Cyanine3 azide chloride can be detected by fluorometers, imagers, and microscopes. (λex=684 nm, λem=710 nm) [1]sup >. Cyanine3 azide (chloride) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    Cyanine3 azide chloride
  • HY-N0733S2
    Glucosamine-13C,15N hydrochloride

    D-(+)-Glucosamine-<sup>13sup>C,<sup>15sup>N hydrochloride; Chitosamine-<sup>13sup>C,<sup>15sup>N hydrochloride

    		 Isotope-Labeled Compounds Autophagy Endogenous Metabolite HIF/HIF Prolyl-Hydroxylase Reactive Oxygen Species Inflammation/Immunology Cancer
    Glucosamine- 13C, 15N (hydrochloride) is the 13C and 15N labeled Glucosamine hydrochloride. Glucosamine hydrochloride (D-Glucosamine hydrochloride) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, i
    Glucosamine-13C,15N hydrochloride
  • HY-B0271S1
    Pyrazinamide-13C,15N

    Pyrazinecarboxamide-<sup>13sup>C,<sup>15sup>N; Pyrazinoic acid amide-<sup>13sup>C,<sup>15sup>N

    		 Autophagy Antibiotic Bacterial Isotope-Labeled Compounds Infection
    Pyrazinamide- 13C, 15N is 15N and 13C labeled Pyrazinamide (HY-B0271). Pyrazinamide (Pyrazinecarboxamide; Pyrazinoic acid amide) is a potent and orally active antitubercular antibiotic. Pyrazinamide is a proagent that is converted to the active form pyrazinoic acid (POA) by PZase/nicotinamidase encoded by the pncA gene in M. tuberculosis.
    Pyrazinamide-13C,15N
  • HY-N0650S6
    L-Serine1-13C,15N

    (-)-Serine-<sup>13sup>C,<sup>15sup>N; (S)-Serine-<sup>13sup>C,<sup>15sup>N

    		 Isotope-Labeled Compounds Endogenous Metabolite Cancer
    L-Serine1- 13C, 15N is the 13C- and 15N-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.
    L-Serine1-13C,15N
  • HY-13100
    PF 03716556

    		Proton Pump Metabolic Disease
    PF 03716556 is a potent, selective, competitive and reversible acid pump (H +,K +-ATPase) antagonist with pIC50s of 6.026, 6.038 and 6.009 for porcine, canine, and human recombinant gastric H +,K +-ATPase, respectively. PF 03716556 is inactive against other receptors, ion channels, and enzymes. PF 03716556 has the potential for gastroesophageal reflux disease research .
    PF 03716556
  • HY-Y0418S
    Dulcite-13C

    Dulcitol-<sup>13sup>C; Melampyrit-<sup>13sup>C; NSC 1944-<sup>13sup>C

    		 Isotope-Labeled Compounds Endogenous Metabolite Others
    Dulcite- 13C is the 13C labeled Dulcite. Dulcite is a sugar alcohol with a slightly sweet taste which is a metabolic breakdown product of galact[1][2].
    Dulcite-13C
  • HY-13771S1
    Ursodeoxycholic acid-13C

    Ursodeoxycholate-<sup>13sup>C; Ursodiol-<sup>13sup>C; UDCA-<sup>13sup>C

    		 Isotope-Labeled Compounds G protein-coupled Bile Acid Receptor 1 FXR Endogenous Metabolite Cancer
    Ursodeoxycholic acid- 13C is the 13C labeled Ursodeoxycholic acid. Ursodeoxycholic acid (Ursodeoxycholate) is a secondary bile acid issued from the transformation of (cheno)deoxycholic acid by intestinal bacteria, acting as a key regulator of the intestinal barrier integrity and essential for lipid metabolism. Ursodeoxycholic acid acts as signaling molecule, exerting its effects by interacting with bile acid activated receptors, including G-protein coupled bile acid receptor 5 (TGR5, GPCR19) and the farnesoid X receptor (FXR). Ursodeoxycholic acid can be used for the research of a variety of hepatic and gastrointestinal diseases. Orally active[1][2].
    Ursodeoxycholic acid-13C
  • HY-15134
    ONT-093

    OC 144-093; OC 144093

    		 P-glycoprotein Cancer
    ONT-093 is a potent inhibitor of P-glycoprotein pump. ONT-093 has the potential for the research cancer diseases .
    ONT-093
  • HY-A0061S
    Trifluridine-13C,15N2

    Trifluorothymidine-<sup>13sup>C,<sup>15sup>N2; 5-Trifluorothymidine-<sup>13sup>C,<sup>15sup>N2; TFT-<sup>13sup>C,<sup>15sup>N2

    		 Thymidylate Synthase Nucleoside Antimetabolite/Analog HSV Orthopoxvirus Cancer
    Trifluridine- 13C, 15N2 is the 13C and 15N labeled Trifluridine[1]. Trifluridine (Trifluorothymidine;5-Trifluorothymidine;TFT) is an irreversible thymidylate synthase inhibitor, and thereby suppresses DNA synthesis. Trifluridine is an antiviral agent for herpes simplex virus (HSV) infection. Trifluorothymidine also has anti-orthopoxvirus activity[2].
    Trifluridine-13C,15N2
  • HY-P4439
    H-Met-Val-OH

    		Amino Acid Derivatives Neurological Disease
    H-Met-Val-OH is a dipeptide containing free N-terminal methionine. H-Met-Val-OH exhibits activity against cDNA expressing Flavin-containing monooxygenase (FMO) 1 and FMO3. H-Met-Val-OH has potential applications in the growth of neuritis .
    H-Met-Val-OH

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