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5 alpha Reductase

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5 alpha Reductase (25) Aldose Reductase (1) HMG-CoA Reductase (HMGCR) (2) IFNAR (20) PGC-1α (10) TrxR (2) α-synuclein (41) 11β-HSD (3) 5-HT Receptor (93) AAK1 (3) Acetyl-CoA Carboxylase (1) Acyltransferase (1) ADC Cytotoxin (6) ADC Linker (8) Adenosine Receptor (5) Adenylate Cyclase (1) Adiponectin Receptor (1) Adrenergic Receptor (381) AIM2 (1) Akt (26) Aldehyde Dehydrogenase (ALDH) (3) Amino Acid Derivatives (30) Aminopeptidase (2) AMPK (28) Amylases (32) Amyloid-β (15) Anaplastic lymphoma kinase (ALK) (1) Androgen Receptor (10) Angiotensin Receptor (1) Angiotensin-converting Enzyme (ACE) (4) Antibiotic (55) Antibody-Drug Conjugates (ADCs) (1) Antifolate (4) AP-1 (2) Apelin Receptor (APJ) (2) Apoptosis (321) Aryl Hydrocarbon Receptor (4) ATF6 (1) Atg8/LC3 (1) ATM/ATR (3) ATP Synthase (3) Aurora Kinase (5) Autophagy (207) Bacterial (132) Bcl-2 Family (8) Bcr-Abl (9) BCRP (1) Beclin1 (3) Beta-secretase (3) Biochemical Assay Reagents (109) c-Fms (6) c-Kit (24) c-Met/HGFR (2) 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(14) Ser/Thr Protease (6) Serotonin Transporter (4) SHP2 (2) Sialyltransferase (4) Sigma Receptor (2) Sirtuin (13) Small Interfering RNA (siRNA) (2) Smo (3) SNIPERs (2) SOD (1) Sodium Channel (19) SphK (2) Src (16) STAT (17) Stearoyl-CoA Desaturase (SCD) (1) STING (5) Syk (3) Target Protein Ligand-Linker Conjugates (1) Taste Receptor (1) Tau Protein (6) TGF-beta/Smad (3) TGF-β Receptor (7) Thrombin (2) Thymidylate Synthase (4) Thyroid Hormone Receptor (25) TNF Receptor (156) Toll-like Receptor (TLR) (38) Topoisomerase (22) Transketolase (1) Trk Receptor (1) TRP Channel (9) TSH Receptor (1) Tyrosinase (20) VD/VDR (18) VEGFR (54) Virus Protease (4) Wnt (12) Xanthine Oxidase (2) β-catenin (6)
By Research Areas:	Cancer (1418) Cardiovascular Disease (304) Endocrinology (384) Infection (298) Inflammation/Immunology (839) Metabolic Disease (680) Neurological Disease (778)
Click Chemistry:	Labeling and Fluorescence Imaging (1) Azide (12) Alkynes (12)

4282

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

144

Biochemical Assay Reagents

356

Peptides

Inhibitory Antibodies

839

Natural
Products

931

Recombinant Proteins

368

Isotope-Labeled Compounds

286

Antibodies

Click Chemistry

Targets Recommended: 5 alpha Reductase Glutathione Reductase Aldose Reductase Dihydrofolate reductase (DHFR) HMG-CoA Reductase (HMGCR) TrxR IFNAR GSNOR α-synuclein PGC-1α

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N3994

16α,17α-Epoxyprogesterone	Others	Others
16α,17α-Epoxyprogesterone is an important steroid, serving as an intermediate for many hormonal drugs such as Hydrocortisone (HY-N0583) and Megestrol (HY-B1834). It can further biotransform into another significant intermediate, 11α-hydroxy-16α,17α-epoxyprogesterone, to manufacture additional compounds .

HY-113097S

3α,7α-Dihydroxycoprostanic acid-d3	Isotope-Labeled Compounds	Others
3α,7α-Dihydroxycoprostanic acid-d₃is the deuterium labeled3α,7α-Dihydroxycoprostanic acid(HY-113097) . 3α,7α-Dihydroxycoprostanic acid is an endogenous metabolite. 3α,7α-Dihydroxycoprostanic acid, a bile acid, is the precursor to chenodeoxycholic acid .

HY-133971

Cholesterol 5α,6α-epoxide 5α,6α-Epoxycholesterol	Liposome	Others
Cholesterol-5α,6α-epoxide is an epoxide derivative of cholesterol formed by the enzymatic oxidation of cholesterol in the liver and other tissues. Cholesterol-5α,6α-epoxide has unique chemical properties that make it an important intermediate in the biosynthesis of bile acids, which play a key role in the digestion and absorption of dietary fats. It also has a potential physiological role in regulating cholesterol metabolism and transport, although its biological function is not fully understood.

HY-15536A

Cebranopadol ((1α,4α)stereoisomer) GRT6005 (1α,4α)stereoisomer	Opioid Receptor	Neurological Disease
Cebranopadol ((1α,4α)stereoisomer) is a stereoisomer of cebranopadol. Cebranopadol is a potent agonist activity on ORL-1.

HY-146225

α-Amylase/α-Glucosidase-IN-2	Glucosidase	Metabolic Disease
α-Amylase/α-Glucosidase-IN-2 (compound 5) is a potent *α-amylase* and *α-glucosidase* dual inhibitor with IC₅₀ values of 13.02, 13.09 µM for α-amylase and α-glucosidase, respectively. α-Amylase/α-Glucosidase-IN-2 has the potential for the research of diabetic complications .

HY-N2853

D-α-Tocopherylquinone α-Tocopherylquinone	Others	Cancer
D-α-Tocopherylquinone (α-Tocopherylquinone) is a quinone, can be isolated from Phaeodactylum tricornutum. D-α-Tocopherylquinone is a oxidation product of α-Tocopherol (vitamin E). D-α-Tocopherylquinone can act as an anticoagulant and as an antioxidant .

HY-147711

α-Amylase/α-Glucosidase-IN-1	Glucosidase	Metabolic Disease
α-Amylase/α-Glucosidase-IN-1 (compound 33) is a potent *α-amylase/α-glucosidase* inhibitor with IC₅₀s of 2.01, 2.09 µM for α-amylase and α-glucosidase, respectively. Kinetic studies predict that α-Amylase/α-Glucosidase-IN-1 has the potential of anti hyperglycemia .

HY-131368

α,α-Trehalose 6-phosphate potassium Tre6P potassium	Endogenous Metabolite	Others
α,α-Trehalose 6-phosphate (Tre6P) potassium is an endogenous metabolite. α,α-Trehalose 6-phosphate is a 6-phosphate derivative of α,α′-trehalose. α,α-Trehalose 6-phosphate is rapidly converted to the pathway end product, α,α′-trehalose, through the action of Tre6P phosphatase (T6PP) .

HY-131368A

α,α-Trehalose 6-phosphate Tre6P	Endogenous Metabolite	Others
α,α-Trehalose 6-phosphate (T6P) is an endogenous metabolite. α,α-Trehalose 6-phosphate is a 6-phosphate derivative of α,α′-trehalose. α,α-Trehalose 6-phosphate is rapidly converted to the pathway end product, α,α′-trehalose, through the action of Tre6P phosphatase (T6PP) .

HY-133971S

Cholesterol-5α,6α-epoxide-d7	Isotope-Labeled Compounds	Others
Cholesterol-5α,6α-epoxide-d₇ is deuterium labeled Cholesterol-5α,6α-epoxide.

HY-P5845

α-Conotoxin RgIA α-RgIA	nAChR	Neurological Disease
α-Conotoxin RgIA (α-RgIA) is a specific α9α10 nAChR antagonist. α-Conotoxin RgIA can be obtained from Conus regius venom. α-Conotoxin RgIA can be used in the study of neurological diseases .

HY-N10639

(1α,2α,6β,8α,9α)-1,2,6,8,12-Pentakis(acetyloxy)-9-(benzoyloxy)dihydro-β-agarofuran	Others	Others
(1α,2α,6β,8α,9α)-1,2,6,8,12-Pentakis(acetyloxy)-9-(benzoyloxy)dihydro-β-agarofuran is a sesquiterpene polyol ester. (1α,2α,6β,8α,9α)-1,2,6,8,12-Pentakis(acetyloxy)-9-(benzoyloxy)dihydro-β-agarofuran can be used for the research of various biochemical .

HY-150857S

Thymine-α,α,α,6-d4 Glycol (mixture of diastereomers)-d4	Isotope-Labeled Compounds	Others
Thymine-α,α,α,6-d₄ Glycol (mixture of diastereomers)-d₄ is the deuterium labeled Thymine-α,α,α,6-d4 Glycol (mixture of diastereomers)[1].

HY-N9487

(R)-(-)-α-Phellandrene (-)-α-Phellandrene	Bacterial	Infection Inflammation/Immunology
(R)-(-)-α-Phellandrene ((-)-α-Phellandrene) is an the (R)-(-)-stereoisomer of α-phellandrene. α-phellandrene is an orally active cyclic monoterpene that attenuates inflammatory response, and induces DNA damage .

HY-162169

α-Amylase/α-Glucosidase-IN-8	Amylases Glucosidase	Metabolic Disease
α-Amylase/α-Glucosidase-IN-8 (Compound 7p) is a potent dual inhibitor of *α-amylase* and *α-glucosidase, with IC₅₀s* of 10.19 and 10.33 μM, respectively. α-Amylase/α-Glucosidase-IN-8 has good anti-oxidant activity(IC₅₀ = 14.93 μM). α-Amylase/α-Glucosidase-IN-8 can be used for the research of diabetes .

HY-162390

α-Amylase/α-Glucosidase-IN-11	Amylases Glucosidase	Endocrinology
α-Amylase/α-Glucosidase-IN-11 (Compound 5d) is a isoxazolidine-isatin hybrid with significant antidiabetic activity. α-Amylase/α-Glucosidase-IN-11 competitively inhibits *α-amylase* (IC₅₀ = 30.39 μM) and *α-glucosidase* (IC₅₀ = 65.1 μM), two key digestive enzymes. α-Amylase/α-Glucosidase-IN-11 does not cross the blood-brain barrier .

HY-161469

α-Amylase/α-Glucosidase-IN-13	Amylases Glucosidase	Metabolic Disease
α-Amylase/α-Glucosidase-IN-13 (Compound 5d) is a dual inhibitor of *α-Amylase/α-Glucosidase* that can be used for diabetes research .

HY-154972

α-Amylase/α-Glucosidase-IN-3	Glucosidase Amylases	Metabolic Disease
α-Amylase/α-Glucosidase-IN-3 (Compound 17) is an *α-Amylase/α-Glucosidase* dual inhibitor, with IC₅₀s of 0.70 μM and 1.10 μM. α-Amylase/α-Glucosidase-IN-3 can be used for research of type-II diabetes mellitus .

HY-149557

α-Amylase/α-Glucosidase-IN-5	Glucosidase Amylases	Metabolic Disease
α-Amylase/α-Glucosidase-IN-5 (compound 4l) is a dual inhibitor of α-glucosidase (Glucosidase) and α-amylase (Amylases) with IC₅₀s of 5.96 μM and 1.62 μM, respectively. α-Amylase/α-Glucosidase-IN-4 has potential antidiabetic activity .

HY-155241

α-Amylase/α-Glucosidase-IN-4	Glucosidase Amylases	Metabolic Disease
α-Amylase/α-Glucosidase-IN-4 (compound 5) is a dual inhibitor of α-glucosidase (Glucosidase) and α-amylase (Amylases) with IC₅₀s of 0.15 μM and 1.10 μM, respectively. α-Amylase/α-Glucosidase-IN-4 has potential antidiabetic activity .

HY-156380

α-Amylase/α-Glucosidase-IN-6	Amylases Glucosidase	Metabolic Disease
α-Amylase/α-Glucosidase-IN-6 (compound 5j) is a potent dual inhibitor of *α-amylase* and *α-glucosidase, with IC₅₀*s of 17.0 and 40.1 µM, respectively. α-Amylase/α-Glucosidase-IN-6 exhibits anti-hyperglycemic activities .

HY-B0892S

Benzyl alcohol-α-13C-α,α-d2 Benzenemethanol-α-¹³C-α,α-d₂	Isotope-Labeled Compounds Endogenous Metabolite	Others
Benzyl alcohol-α- ¹³C-α,α-d₂ is the ¹³C-labeled Benzyl alcohol. Benzyl alcohol is an aromatic alcohol; a colorless liquid with a mild pleasant aromatic odor.

HY-N10564

8α,9α-Epoxycoleon-U-quinone	P-glycoprotein	Cancer
8α,9α-Epoxycoleon-U-quinone (compound 3) is a p-glycoprotein (P-gp) regulator that is selective for cancer cells (SI=2.0). 8α,9α-Epoxycoleon-U-quinone effectively inhibits P-gp activity in NCI-H460/R cells. 8α,9α-Epoxycoleon-U-quinone also reverses the resistance of cancer cells to Doxorubicin (DOX) (HY-15142A) and enhances the anticancer effect of DOX .

HY-162036

α-Amylase/α-Glucosidase-IN-7	Glucosidase Amylases Cholinesterase (ChE)	Neurological Disease Metabolic Disease
α-Amylase/α-Glucosidase-IN-7 (Compound 3f) is a competitive *α-glucosidase* and *α-amylase* enzyme inhibitor with IC₅₀ values of 18.52 and 20.25 µM, respectively. α-Amylase/α-Glucosidase-IN-7 can also effectively inhibit AChE and BChE, with IC₅₀ values of 9.25 and 10.06 µM respectively. α-Amylase/α-Glucosidase-IN-7 can be used in diabetes and Alzheimer’s research .

HY-N2514

α-Lactose α-D-Lactose	Others	Others
α-Lactose (α-D-Lactose) is the major sugar present in milk. Lactose exists in the form of two anomers, α and β. The α form normally crystallizes as a monohydrate .

HY-W127508

α,α'-Dilaurin	Biochemical Assay Reagents	Others
α,α'-Dilaurin is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-130529

OH-α-PVP TFA OH-α-Pyrrolidinovalerophenone TFA	Endogenous Metabolite	Metabolic Disease
OH-α-PVP (OH-α-Pyrrolidinovalerophenone ) TFA is a metabolite of α-pyrrolidinovalerophenone. α-pyrrolidinovalerophenone is a synthetic stimulant of the cathinone class .

HY-W399297

Isodeoxycholic acid 7α,12α-Dihydroxycholanoic acid	Endogenous Metabolite	Metabolic Disease
Isodeoxycholic acid (7α,12α-Dihydroxycholanoic acid) is the 3β-epimer of ursodeoxycholic acid. Isodeoxycholic acid has the effect on choleresis and liver biochemistry .

HY-114656

Dihydro-PGF1α Dihydroprostaglandin F1α	Others	Endocrinology
Dihydro-PGF1α is a potential metabolite of PGF1α .

HY-P5859

α-Pompilidotoxin α-PMTX	Biochemical Assay Reagents	Neurological Disease
α-Pompilidotoxin (α-PMTX) is a neurotoxin that can be obtained from the venom of Anoplius safnariensis. α-Pompilidotoxin reversibly and dose-dependently enhances excitatory postsynaptic currents (EPSCs). α-Pompilidotoxin is a useful tool in the field of neuroscience research .

HY-N1467

(-)-α-Terpineol (S)-α-Terpineol	Others	Others
(-)-α-Terpineol ((S)-α-Terpineol), a monoterpene compound, is one of compounds in Melaleuca alternifolia. (-)-α-Terpineol has antioxidant and anti-inflammatory activities .

HY-N0611

alpha-Boswellic acid α-Boswellic acid	Others	Neurological Disease Inflammation/Immunology Cancer
alpha-Boswellic acid (α-Boswellic acid) is an orally active pentacyclic triterpenoid compound that can be extracted from frankincense. alpha-Boswellic acid has anti-inflammatory and antitumor activities. alpha-Boswellic acid can be used in Alzheimer's disease (AD) research .

HY-N8459

α-Cembrenediol α-CBD	EBV	Cancer
α-Cembrenediol is a potent inhibitor of *EBV*.α-Cembrenediol inhibits the early antigen of the Epstein-Bar virus. α-Cembrenediol also has anti-tumour activity .

HY-N9960

α-Isopropylmalate α-IPM	Others	Others
α-Isopropylmalate (α-IPM) is the leucine biosynthetic precursor in Yeast .

HY-N0176A

α-Dihydroartemisinin α-Dihydroqinghaosu; α-Artenimol	Parasite	Infection
α-Dihydroartemisinin is a natural product that can be found in artemisinin. α-Dihydroartemisinin also shows antimalarial activity .

HY-133966S

6α-Hydroxy-5α-cholestane-d7	Isotope-Labeled Compounds	Others
6α-Hydroxy-5α-cholestane-d₇ is deuterium labeled 6α-Hydroxy-5α-cholestane.

HY-161355

α-Amylase/α-Glucosidase-IN-9	Amylases Glucosidase	Metabolic Disease
α-Amylase/α-Glucosidase-IN-9 (compound 5h) is a dual inhibitor for both *α-amylase* (IC₅₀ = 16.4 μM) and *α-glucosidase* (IC₅₀ = 31.6 μM) enzymes .

HY-129953S1

9α,11β-Prostaglandin F2α-d9	Endogenous Metabolite Isotope-Labeled Compounds	Others
9α,11β-Prostaglandin F2α-d₉ is the deuterium labeled 9α,11β-Prostaglandin F2α[1].

HY-162373

α-Amylase/α-Glucosidase-IN-10	Amylases Glucosidase P-glycoprotein	Metabolic Disease
α-Amylase/α-Glucosidase-IN-10 (compound 5d) is an α-amylase and α-glucosidase inhibitor (IC₅₀: 30.39 μM and 65.1 μM) with potential diabetes inhibitory effects. α-Amylase/α-Glucosidase-IN-10 exhibits high gastrointestinal (GI) absorption in ADMET (Absorption, Distribution, Metabolism, Excretion and Toxicity) prediction. While α-Amylase/α-Glucosidase-IN-10 acts as a substrate for P-gp and does not cross the blood-brain barrier (BBB), there may be a risk of central nervous system side effects .

HY-163439

α-Amylase/α-Glucosidase-IN-12	Amylases Glucosidase	Metabolic Disease
α-Amylase/α-Glucosidase-IN-12 (compound 10k) is a dual inhibitor targeting α-glucosidase and α-amylase with IC₅₀ of 34.52 nM and 24.62 nM, respectively. α-Amylase/α-Glucosidase-IN-12 is an inhibitor designed based on triazolo[4,3-b][1,2,4]triazine and has the potential to be used in diabetes research .

HY-P2802

α-Glucosidase α-D-Glucosidase	Glucosidase	Metabolic Disease
α-Glucosidase (α-D-Glucosidase), a carbohydrate hydrolyzing enzyme, catalyzes the liberation of α-glucose from the non-reducing end of the substrate. α-Glucosidase can facilitate the absorption of glucose by the small intestine. Inhibition of α-Glucosidase is an effective management of non-insulin-dependent diabetes mellitus (NIDDM) .

HY-N9960R

α-Isopropylmalate (Standard) α-IPM (Standard)	Others	Others
α-Isopropylmalate (Standard) is the analytical standard of α-Isopropylmalate. This product is intended for research and analytical applications. α-Isopropylmalate (α-IPM) is the leucine biosynthetic precursor in Yeast .

HY-129953S

9α,11β-Prostaglandin F2α-d4	Isotope-Labeled Compounds Endogenous Metabolite	Inflammation/Immunology
9α,11β-Prostaglandin F2α-d4 is a deuterated labeled 9α,11β-Prostaglandin F2α . 9α,11β-Prostaglandin F2α is an endogenous metabolite present in Urine that can be used for the research of Asthma .

HY-129953B

15(R)-Prostaglandin F2α 15-epi PGF2α; 15(R)-PGF2α	Endogenous Metabolite	Inflammation/Immunology
15(R)-Prostaglandin F2α is the isomer of 9α,11β-Prostaglandin F2α (HY-129953). 9α,11β-Prostaglandin F2α is an endogenous metabolite present in Urine that can be used for the research of Asthma .

HY-W087904

α-Lactose hydrate α-D-Lactose hydrate	Endogenous Metabolite	Others
α-Lactose (hydrate) (α-D-Lactose (hydrate)) is the principal carbohydrate in the milk of most mammals. α-Lactose (hydrate) consists of glucose and galactose and exists in the form of two anomers, α and β. α-Lactose (hydrate) has many uses in the food and pharmaceutical industries, such as a free-flowing or agglomerating agent, a diluent for pigments, flavors, or enzymes .

HY-121615

α-Phellandrene alpha-Phellandrene	Fungal	Infection
α-Phellandrene (alpha-Phellandrene) has antifungal activity. α-Phellandrene significantly inhibits the hyphal growth of P. cyclopium, destroys their cell membrane integrity and causes leakage of cellular components .

HY-N0683

α-Vitamin E 10+ Cited Publications (+)-α-Tocopherol; D-α-Tocopherol	Bacterial Influenza Virus Reactive Oxygen Species Ferroptosis Endogenous Metabolite	Infection Cancer
α-Vitamin E ((+)-α-Tocopherol), a naturally occurring vitamin E form, is a potent antioxidant .

HY-133890A

Tauro-α-muricholic acid sodium T-α-MCA sodium	Endogenous Metabolite FXR	Others
Tauro-α-muricholic acid (T-α-MCA) sodium is a FXR (Farnesoid X receptor) antagonist (IC₅₀=28μM). Tauro-α-muricholic acid sodium is also a endogenous metabolite that can be found in cecal .

HY-133890

Tauro-α-muricholic acid T-α-MCA	Endogenous Metabolite FXR	Cardiovascular Disease Others Metabolic Disease
Tauro-alpha-muricholic acid (T-alpha-MCA) is a bile acid that belongs to a class of compounds that are synthesized in the liver and play an important role in the digestive process. Tauro-α-muricholic acid activates Farni X receptors (FXR) which are involved in the regulation of bile acid synthesis, metabolism and transport. Tauro-alpha-muricholic acid can be used in the study of metabolic syndrome and cardiovascular disease .

HY-N1720

2α,3α,24-Trihydroxyolean-12-en-28-oic acid	Others	Others
2α,3α,24-Trihydroxyolean-12-en-28-oic acid (compound 5) is a terpenoid that is isolated from the branches and leaves of Pyrus pashia. 2α,3α,24-Trihydroxyolean-12-en-28-oic acid shows cytotoxic activity .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N2853

D-α-Tocopherylquinone α-Tocopherylquinone	Quinones Microorganisms Classification of Application Fields Source classification Benzene Quinones Disease Research Fields Cancer	Others
D-α-Tocopherylquinone (α-Tocopherylquinone) is a quinone, can be isolated from Phaeodactylum tricornutum. D-α-Tocopherylquinone is a oxidation product of α-Tocopherol (vitamin E). D-α-Tocopherylquinone can act as an anticoagulant and as an antioxidant .

HY-131368

α,α-Trehalose 6-phosphate potassium Tre6P potassium	Structural Classification Source classification Arabidopsis thaliana (L.) Heynh. Plants Brassicaceae Saccharides	Endogenous Metabolite
α,α-Trehalose 6-phosphate (Tre6P) potassium is an endogenous metabolite. α,α-Trehalose 6-phosphate is a 6-phosphate derivative of α,α′-trehalose. α,α-Trehalose 6-phosphate is rapidly converted to the pathway end product, α,α′-trehalose, through the action of Tre6P phosphatase (T6PP) .

HY-131368A

α,α-Trehalose 6-phosphate Tre6P	Structural Classification Human Gut Microbiota Metabolites Polysaccharides Microorganisms Source classification Endogenous metabolite Saccharides	Endogenous Metabolite
α,α-Trehalose 6-phosphate (T6P) is an endogenous metabolite. α,α-Trehalose 6-phosphate is a 6-phosphate derivative of α,α′-trehalose. α,α-Trehalose 6-phosphate is rapidly converted to the pathway end product, α,α′-trehalose, through the action of Tre6P phosphatase (T6PP) .

HY-N9487

(R)-(-)-α-Phellandrene (-)-α-Phellandrene	Structural Classification Other Monoterpenes Terpenoids Plants Schinus terebinthifolius Raddi Anacardiaceae	Bacterial
(R)-(-)-α-Phellandrene ((-)-α-Phellandrene) is an the (R)-(-)-stereoisomer of α-phellandrene. α-phellandrene is an orally active cyclic monoterpene that attenuates inflammatory response, and induces DNA damage .

HY-N10564

8α,9α-Epoxycoleon-U-quinone	Structural Classification Ketones, Aldehydes, Acids Labiatae Smallanthus uvedalia (Linnaeus) Mackenzie Plants	P-glycoprotein
8α,9α-Epoxycoleon-U-quinone (compound 3) is a p-glycoprotein (P-gp) regulator that is selective for cancer cells (SI=2.0). 8α,9α-Epoxycoleon-U-quinone effectively inhibits P-gp activity in NCI-H460/R cells. 8α,9α-Epoxycoleon-U-quinone also reverses the resistance of cancer cells to Doxorubicin (DOX) (HY-15142A) and enhances the anticancer effect of DOX .

HY-N2514

α-Lactose α-D-Lactose	Polysaccharides Classification of Application Fields Animals Source classification Other Diseases Disease Research Fields Saccharides	Others
α-Lactose (α-D-Lactose) is the major sugar present in milk. Lactose exists in the form of two anomers, α and β. The α form normally crystallizes as a monohydrate .

HY-W399297

Isodeoxycholic acid 7α,12α-Dihydroxycholanoic acid	Structural Classification Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite
Isodeoxycholic acid (7α,12α-Dihydroxycholanoic acid) is the 3β-epimer of ursodeoxycholic acid. Isodeoxycholic acid has the effect on choleresis and liver biochemistry .

HY-N1467

(-)-α-Terpineol (S)-α-Terpineol	Other Terpenoids Melaleuca alternifolia Structural Classification Classification of Application Fields Terpenoids Source classification Other Diseases Myrtaceae Plants Disease Research Fields	Others
(-)-α-Terpineol ((S)-α-Terpineol), a monoterpene compound, is one of compounds in Melaleuca alternifolia. (-)-α-Terpineol has antioxidant and anti-inflammatory activities .

HY-N0611

alpha-Boswellic acid α-Boswellic acid	Triterpenes Structural Classification Classification of Application Fields Terpenoids Source classification Boswellia serrata Plants Burseraceae Inflammation/Immunology Disease Research Fields	Others
alpha-Boswellic acid (α-Boswellic acid) is an orally active pentacyclic triterpenoid compound that can be extracted from frankincense. alpha-Boswellic acid has anti-inflammatory and antitumor activities. alpha-Boswellic acid can be used in Alzheimer's disease (AD) research .

HY-N8459

α-Cembrenediol α-CBD	Structural Classification Natural Products Nicotiana tabacum L. Source classification Plants Solanaceae	EBV
α-Cembrenediol is a potent inhibitor of *EBV*.α-Cembrenediol inhibits the early antigen of the Epstein-Bar virus. α-Cembrenediol also has anti-tumour activity .

HY-N9960

α-Isopropylmalate α-IPM	Structural Classification Microorganisms Animals Ketones, Aldehydes, Acids Source classification	Others
α-Isopropylmalate (α-IPM) is the leucine biosynthetic precursor in Yeast .

HY-N0176A

α-Dihydroartemisinin α-Dihydroqinghaosu; α-Artenimol	Structural Classification Terpenoids Sesquiterpenes Source classification Artemisia carvifolia Buch.-Ham. ex Roxb. Plants Compositae	Parasite
α-Dihydroartemisinin is a natural product that can be found in artemisinin. α-Dihydroartemisinin also shows antimalarial activity .

HY-N9960R

α-Isopropylmalate (Standard) α-IPM (Standard)	Structural Classification Microorganisms Animals Ketones, Aldehydes, Acids Source classification	Others
α-Isopropylmalate (Standard) is the analytical standard of α-Isopropylmalate. This product is intended for research and analytical applications. α-Isopropylmalate (α-IPM) is the leucine biosynthetic precursor in Yeast .

HY-W087904

α-Lactose hydrate α-D-Lactose hydrate	Structural Classification Polysaccharides Animals Source classification Saccharides	Endogenous Metabolite
α-Lactose (hydrate) (α-D-Lactose (hydrate)) is the principal carbohydrate in the milk of most mammals. α-Lactose (hydrate) consists of glucose and galactose and exists in the form of two anomers, α and β. α-Lactose (hydrate) has many uses in the food and pharmaceutical industries, such as a free-flowing or agglomerating agent, a diluent for pigments, flavors, or enzymes .

HY-121615

α-Phellandrene alpha-Phellandrene	Melaleuca alternifolia Structural Classification Other Monoterpenes Terpenoids Source classification Myrtaceae Plants	Fungal
α-Phellandrene (alpha-Phellandrene) has antifungal activity. α-Phellandrene significantly inhibits the hyphal growth of P. cyclopium, destroys their cell membrane integrity and causes leakage of cellular components .

HY-N0683

α-Vitamin E 10+ Cited Publications (+)-α-Tocopherol; D-α-Tocopherol	Infection Classification of Application Fields Moisture Cosmetic Research Disease Research Fields Cancer Food Research	Bacterial Influenza Virus Reactive Oxygen Species Ferroptosis Endogenous Metabolite
α-Vitamin E ((+)-α-Tocopherol), a naturally occurring vitamin E form, is a potent antioxidant .

HY-133890A

Tauro-α-muricholic acid sodium T-α-MCA sodium	Structural Classification Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite FXR
Tauro-α-muricholic acid (T-α-MCA) sodium is a FXR (Farnesoid X receptor) antagonist (IC₅₀=28μM). Tauro-α-muricholic acid sodium is also a endogenous metabolite that can be found in cecal .

HY-133890

Tauro-α-muricholic acid T-α-MCA	Structural Classification Human Gut Microbiota Metabolites Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Endogenous Metabolite FXR
Tauro-alpha-muricholic acid (T-alpha-MCA) is a bile acid that belongs to a class of compounds that are synthesized in the liver and play an important role in the digestive process. Tauro-α-muricholic acid activates Farni X receptors (FXR) which are involved in the regulation of bile acid synthesis, metabolism and transport. Tauro-alpha-muricholic acid can be used in the study of metabolic syndrome and cardiovascular disease .

HY-N1720

2α,3α,24-Trihydroxyolean-12-en-28-oic acid	Triterpenes Classification of Application Fields Terpenoids Pyrus pashia Buch.-Ham. ex D. Don Source classification Rosaceae Other Diseases Plants Disease Research Fields	Others
2α,3α,24-Trihydroxyolean-12-en-28-oic acid (compound 5) is a terpenoid that is isolated from the branches and leaves of Pyrus pashia. 2α,3α,24-Trihydroxyolean-12-en-28-oic acid shows cytotoxic activity .

HY-129953

9α,11β-Prostaglandin F2α	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite
9α,11β-Prostaglandin F2α is an endogenous metabolite present in Urine that can be used for the research of Asthma .

HY-W020044

*DL-alpha-Tocopherol* 2 Publications Verification DL-α-Tocopherol	Duchesnea indica (Andr.) Focke Monophenols Classification of Application Fields Source classification Other Diseases Rosaceae Phenols Plants Disease Research Fields	Ferroptosis
DL-alpha-Tocopherol is a synthetic vitamin E, with antioxidation effect. DL-alpha-Tocopherol protects human skin fibroblasts against the cytotoxic effect of UVB .

HY-116757

(±)-α-CMBHC	Cardiovascular Disease Structural Classification Monophenols Classification of Application Fields Ketones, Aldehydes, Acids Source classification Phenols Endogenous metabolite Disease Research Fields	Endogenous Metabolite
(±)-α-CMBHC is a metabolite of α-Tocopherol .

HY-N0683A

rel-α-Vitamin E rel-D-α-Tocopherol	Natural Products Monophenols other families Classification of Application Fields Source classification Phenols Plants Inflammation/Immunology Disease Research Fields	Others
rel-α-Vitamin E (rel-D-α-Tocopherol) is a vitamin with antioxidant properties and also a mixture .

HY-N0700

alpha-Asarone α-Asarone; trans-Asarone	Acorus tatarinowii Schott Structural Classification Simple Phenylpropanols Araceae Source classification Phenylpropanoids Plants	GABA Receptor
alpha-Asarone (α-Asarone) is one of the main psychoactive compounds, and possesses an antidepressant-like activity in mice.

HY-N9699

8α-Hydroxyhirsutinolide	Structural Classification Terpenoids Sesquiterpenes Source classification Plants Compositae Vachellia nilotica (L.) P. J. H. Hurter & Mabb.	NF-κB
8α-Hydroxyhirsutinolide is a sesquiterpene lactone. 8α-Hydroxyhirsutinolide inhibits TNF-α-induced NF-κB activity (IC₅₀: 1.9 μM) and NO production. 8α-Hydroxyhirsutinolide can be isolated from Vernonia cinerea .

HY-N8908

2α,9α,11-Trihydroxy-6-oxodrim-7-ene	Other Terpenoids Structural Classification Microorganisms Terpenoids Source classification	Others
2α,9α,11-Trihydroxy-6-oxodrim-7-ene is a natural product that can be isolated from the culture medium of the marine-derived fungus Aspergillus insuetus .

HY-N1820

3α-Akebonoic acid	Triterpenes Structural Classification Terpenoids Lardizabalaceae Akebia trifoliata (Thunb.) Koidz. Source classification Plants	Bacterial Glucosidase
3α-Akebonoic acid is a *α-glucosidase* inhibitor with an IC₅₀ value of 0.035 mM. 3α-Akebonoic acid shows antibacterial activity and cytotoxicity .

HY-N8745

α-Peltatin	Structural Classification Podophyllum peltatum L. Source classification Lignans Phenylpropanoids Plants Berberidaceae	Fungal
α-Peltatin is an aryl lignan. α-Peltatin has anticancer and antifungal activity. α-Peltatin inhibits DNA topoisomerase and tubulin polymerization .

HY-N0255

alpha-Hederin α-Hederin	Triterpenes Hedera nepalensis K. Koch var. sinensis (Tobl.) Rehd. Classification of Application Fields Terpenoids Source classification Other Diseases Plants Disease Research Fields Araliaceae	Apoptosis
alpha-Hederin (α-Hederin), a monodesmosidic triterpenoid saponin, exhibits promising antitumor potential against a variety of human cancer cell lines. alpha-Hederin could inhibit the proliferation and induce apoptosis of gastric cancer accompanied by glutathione decrement and reactive oxygen species generation via activating mitochondrial dependent pathway .

HY-113962

7α,25-Dihydroxycholesterol 1 Publications Verification 7α,25-OHC	Structural Classification Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields Steroids	EBI2/GPR183 Endogenous Metabolite
7α, 25-dihydroxycholesterol (7α,25-OHC) is a potent and selective agonist and endogenous ligand of the orphan GPCR receptor EBI2 (GPR183). 7α, 25-dihydroxycholesterol is highly potent at activating EBI2 (EC₅₀=140 pM; K_d=450 pM). 7α, 25-dihydroxycholesterol can serve as a chemokine directing migration of B cells, T cells and dendritic cells .

HY-N0492

α-Lipoic Acid 5 Publications Verification Thioctic acid; (±)-α-Lipoic acid; DL-α-Lipoic acid	Infection Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	NF-κB HIV Mitochondrial Metabolism Endogenous Metabolite Apoptosis
α-Lipoic Acid (Thioctic acid) is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. α-Lipoic Acid inhibits NF-κB-dependent HIV-1 LTR activation . α-Lipoic Acid induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells . α-Lipoic Acid can be used with CPUL1 (HY-151802) to construct the self-assembled nanoaggregate CPUL1-LA NA, which has improved antitumor efficacy than CPUL1 .

HY-N0492A

α-Lipoic Acid sodium Thioctic acid sodium; (±)-α-Lipoic acid sodium; DL-α-Lipoic acid sodium	Infection Natural Products Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields Cancer	NF-κB HIV Mitochondrial Metabolism Endogenous Metabolite Apoptosis
α-Lipoic Acid (Thioctic acid) sodium is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. α-Lipoic Acid sodium inhibits NF-κB-dependent HIV-1 LTR activation . α-Lipoic Acid sodium induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells . α-Lipoic Acid sodium can be used with CPUL1 (HY-151802) to construct the self-assembled nanoaggregate CPUL1-LA NA, which has improved antitumor efficacy than CPUL1 .

HY-B2193

α-Amylase	Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Other Diseases Disease Research Fields	Others
α-Amylase is a hydrolase enzyme that catalyses the hydrolysis of internal α-1, 4-glycosidic linkages in starch to yield products like glucose and maltose.

HY-N10910

α-Isolupanine	Structural Classification Alkaloids Piperidine Alkaloids Leguminosae Source classification Lupinus angustifolius L. Plants	Others
α-Isolupanine is an alkaloid. α-Isolupanine can be isolated from Narrow-Leafed Lupin (PLupinus angustifolius L.). α-Isolupanine can be used for the research of anthracnose .

HY-N7563

α-Toxicarol	Structural Classification Flavonoids Leguminosae Source classification Derris trifoliata Lour. Plants Other Flavonoids	EBV
α-Toxicarol is a potent inhibitor of *EBV*.α-Toxicarol significantly inhibits mouse skin tumor in vivo. α-Toxicarol inhibits the TPA-induced EBV-EA activation .

HY-N0492R

α-Lipoic Acid (Standard) 5 Publications Verification Thioctic acid (Standard); (±)-α-Lipoic acid (Standard); DL-α-Lipoic acid (Standard)	Infection Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	NF-κB HIV Mitochondrial Metabolism Endogenous Metabolite Apoptosis
α-Lipoic Acid (Standard) is the analytical standard of α-Lipoic Acid. This product is intended for research and analytical applications. α-Lipoic Acid (Thioctic acid) is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. α-Lipoic Acid inhibits NF-κB-dependent HIV-1 LTR activation . α-Lipoic Acid induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells . α-Lipoic Acid can be used with CPUL1 (HY-151802) to construct the self-assembled nanoaggregate CPUL1-LA NA, which has improved antitumor efficacy than CPUL1 .

HY-N0328R

alpha-Mangostin (Standard) α-Mangostin (Standard)	Structural Classification other families Xanthones Classification of Application Fields Source classification Phenols Polyphenols Plants Disease Research Fields Cancer	Fungal Reactive Oxygen Species Bacterial Apoptosis Virus Protease
alpha-Mangostin (Standard) is the analytical standard of alpha-Mangostin. This product is intended for research and analytical applications. alpha-Mangostin (α-Mangostin) is a dietary xanthone with broad biological activities, such as antioxidant, anti-allergic, antiviral, antibacterial, anti-inflammatory and anticancer effects. It is an inhibitor of mutant IDH1 (IDH1-R132H) with a K_i of 2.85 μM.

HY-N0710

alpha-Cyperone 2 Publications Verification α-Cyperone; (+)-α-Cyperone	Structural Classification other families Classification of Application Fields Terpenoids Sesquiterpenes Source classification Plants Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite
alpha-Cyperone (α-Cyperone) is associated with the down-regulation of COX-2, IL-6, Nck-2, Cdc42 and Rac1, resulting in reduction of inflammation, which would be highly beneficial for treatment of inflammatory diseases such as AD.

HY-P1482

α-Factor Mating Pheromone, yeast 1 Publications Verification Mating Factor α	Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields Endocrinology	Others
α-Factor Mating Pheromone, yeast is a tridecapeptide secreted by S. cerevisiae α cells via Ste2p receptor.

HY-119593

α-Homonojirimycin Homonojirimycin	Structural Classification Natural Products Source classification Omphalea diandra Vell. Euphorbiaceae Plants	Glucosidase
α-Homonojirimycin is a potent *α-glucosidase* inhibitor .

HY-W014118

α-Hexylcinnamaldehyde	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields Cancer	Others
α-Hexylcinnamaldehyde, a compound derived from Cinnamaldehyde. α-Hexylcinnamaldehyde has the potential antimutagenic and chemosensitizing properties. α-Hexylcinnamaldehyde is widely used as an ingredient in many personal care, and as an additive in food and the pharmaceutical industry .

HY-N1719

Isoarjunolic acid 2α,3α,23-Trihydroxyolean-12-en-28-oic acid	Rhododendron collettianum Aitch. & Hemsl. Ericaceae Plants	Others
Isoarjunolic acid (2α,3α,23-Trihydroxyolean-12-en-28-oic acid) is a triterpenoid, can be isolated from the stems of Cornus kousa. Isoarjunolic acid could have free radical scavenging activity and elastase inhibition activity .

HY-N2794

9-Hydroxy-α-lapachone α-Dihydrocaryopterone	Quinones Structural Classification Catalpa ovata G. Don Monophenols Source classification Phenols Plants Bignoniaceae Naphthalene Quinones	NO Synthase
9-Hydroxy-α-lapachone (α-Dihydrocaryopterone) is a natural phenol, exhibits potent inhibitory effects with an IC₅₀ of 4.64 µM on LPS-induced NO production in RAW 264.7 cells .

HY-N12876

(18α)-Oleanolic acid (18α)-Oleanic acid; (18α)-Caryophyllin	Structural Classification Ketones, Aldehydes, Acids Terpenoids Source classification Vitis vinifera cv. Zalema Plants Vitaceae Pentacyclic Triterpenoids	Others
18α-Oleanolic acid is a natural pentacyclic triterpenic acid that can be isolated from plants .

HY-W020044R

*DL-alpha-Tocopherol (Standard)* 2 Publications Verification	Structural Classification Duchesnea indica (Andr.) Focke Classification of Application Fields Source classification Other Diseases Rosaceae Phenols Plants Disease Research Fields	Ferroptosis
DL-alpha-Tocopherol (Standard) is the analytical standard of DL-alpha-Tocopherol. This product is intended for research and analytical applications. DL-alpha-Tocopherol is a synthetic vitamin E, with antioxidation effect. DL-alpha-Tocopherol protects human skin fibroblasts against the cytotoxic effect of UVB .

HY-121618

α-Thujone	Infection Other Monoterpenes Platycladus orientalis (Linn.) Franco Cupressaceae Classification of Application Fields Neurological Disease Terpenoids Source classification Plants Disease Research Fields	GABA Receptor Reactive Oxygen Species Parasite Apoptosis Autophagy
α-Thujone is a monoterpene isolated from Thuja occidentalis essential oil with potent anti-tumor activities. α-Thujone is a reversible modulator of the GABA type A receptor and the IC₅₀ for α-Thujone is 21 μM in suppressing the GABA-induced currents. α-Thujone induces ROS accumulation-dependent cytotoxicity, also induces cell apoptosis and autophagy. α-Thujone has antinociceptive, insecticidal, and anthelmintic activity, and easily penetrates the blood-brain barrier .

HY-N3002

α-Arbutin 4-Hydroxyphenyl α-D-glucopyranoside	Monophenols Classification of Application Fields Source classification Phenols Metabolic Disease Cosmetic Research Plants Ericaceae Disease Research Fields	Tyrosinase
α-Arbutin (4-Hydroxyphenyl α-D-glucopyranoside) is emerging as popular and effective skin whiteners, acting as tyrosinase inhibitor .

HY-137178

20α,22R-Dihydroxycholesterol	Structural Classification Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields Steroids	Endogenous Metabolite
20α,22R-Dihydroxycholesterol is an endogenous metabolic intermediate. 20α,22R-Dihydroxycholesterol involved in the biosynthesis of cholesterol to steroid hormones .

HY-N4155

2α,19α-Dihydroxy-3-oxo-urs-12-en-28-oic acid	Rosaceae Rosa cymosa (L.) Tratt. Plants	EBV HIV Protease HSV
2α,19α-Dihydroxy-3-oxo-urs-12-en-28-oic acid, a natural ursane-type triterpene, is a potent inhibitor of HIV protease (HIV Protease). 2α,19α-Dihydroxy-3-oxo-urs-12-en-28-oic acid is also an inhibitor of the activation of Epstein-Barr virus early antigen (EBV-EA). 2α,19α-Dihydroxy-3-oxo-urs-12-en-28-oic acid displays an inhibitory activity against nitric oxide production in Lipopolysaccharide (Lipopolysaccharides)-activated RAW 264.7 cells .

HY-122485

α-Copaene	Structural Classification Natural Products Classification of Application Fields Leguminosae Source classification Other Diseases Sindora Plants Disease Research Fields	Others
α-Copaene, a sesquiterpene hydrocarbon, is a fruit volatile. α-Copaene can be used as an oviposition promoter of Bactrocera oleae .

Cat. No.	Product Name	Chemical Structure

HY-113097S

3α,7α-Dihydroxycoprostanic acid-d3
3α,7α-Dihydroxycoprostanic acid-d₃is the deuterium labeled3α,7α-Dihydroxycoprostanic acid(HY-113097) . 3α,7α-Dihydroxycoprostanic acid is an endogenous metabolite. 3α,7α-Dihydroxycoprostanic acid, a bile acid, is the precursor to chenodeoxycholic acid .

HY-133971S

Cholesterol-5α,6α-epoxide-d7
Cholesterol-5α,6α-epoxide-d₇ is deuterium labeled Cholesterol-5α,6α-epoxide.

HY-150857S

Thymine-α,α,α,6-d4 Glycol (mixture of diastereomers)-d4
Thymine-α,α,α,6-d₄ Glycol (mixture of diastereomers)-d₄ is the deuterium labeled Thymine-α,α,α,6-d4 Glycol (mixture of diastereomers)[1].

HY-B0892S

Benzyl alcohol-α-13C-α,α-d2
Benzyl alcohol-α- ¹³C-α,α-d₂ is the ¹³C-labeled Benzyl alcohol. Benzyl alcohol is an aromatic alcohol; a colorless liquid with a mild pleasant aromatic odor.

HY-133966S

6α-Hydroxy-5α-cholestane-d7
6α-Hydroxy-5α-cholestane-d₇ is deuterium labeled 6α-Hydroxy-5α-cholestane.

HY-129953S1

9α,11β-Prostaglandin F2α-d9
9α,11β-Prostaglandin F2α-d₉ is the deuterium labeled 9α,11β-Prostaglandin F2α[1].

HY-129953S

9α,11β-Prostaglandin F2α-d4
9α,11β-Prostaglandin F2α-d4 is a deuterated labeled 9α,11β-Prostaglandin F2α . 9α,11β-Prostaglandin F2α is an endogenous metabolite present in Urine that can be used for the research of Asthma .

HY-Y0149S

3,4-Dimethoxyphenylacetonitrile-α,α-d2
3,4-Dimethoxyphenylacetonitrile-α,α-d₂ is the deuterium labeled (3,4-Dimethoxyphenyl)acetonitrile[1].

HY-113962S

7α,25-Dihydroxycholesterol-d6
7α,25-Dihydroxycholesterol-d₆ is deuterium labeled 7α,25-Dihydroxycholesterol. 7α, 25-dihydroxycholesterol (7α,25-OHC) is a potent and selective agonist and endogenous ligand of the orphan GPCR receptor EBI2 (GPR183). 7α, 25-dihydroxycholesterol is highly

HY-B1204S

Histamine-α,α,β,β-d4 dihydrochloride
Histamine-α,α,β,β-d₄ (dihydrochloride) is the deuterium labeled Histamine. Histamine is an organic nitrogenous compound involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter.

HY-123489S

3α,21-Dihydroxy-5α-pregnan-20-one-d3
3α,21-Dihydroxy-5α-pregnan-20-one-d₃ is the deuterium labeled 3α,21-Dihydroxy-5α-pregnan-20-one. 3α,21-Dihydroxy-5α-pregnan-20-one (THDOC), an endogenous neurosteroid, is a positive modulator of GABAA receptors. 3α,21-Dihydroxy-5α-pregnan-20-one potentiates neuronal response to low concentrations of GABA at α4β1δ GABAA receptors in vitro.

HY-146788S

7α,27-Dihydroxycholesterol-d6
7α,27-Dihydroxycholesterol-d₆ is deuterium labeled 7α,27-Dihydroxycholesterol.

HY-B1278S1

α-Tocopherol-d6 acetate
α-Tocopherol-d₆ (acetate) is the deuterium labeled D-α-Tocopherol acetate. D-α-Tocopherol acetate (D-Vitamin E acetate) can be hydrolyzed to d-alpha-tocopherol (VE) and absorbed in the small intestine[1].

HY-113031S

16α-Hydroxydehydroepiandrosterone-d5
16α-Hydroxydehydroepiandrosterone-d₅ (16α-Hydroxy-DHEA-d₅) is the deuterium labeled 16α-Hydroxydehydroepiandrosterone[1].

HY-N0683S3

l-α-Tocopherol-d9
α-Vitamin E-d₉ is the deuterium labeled α-Vitamin E[1]. α-Vitamin E ((+)-α-Tocopherol), a naturally occurring vitamin E form, is a potent antioxidant[2][3].

HY-N7148S

α-Vitamin E-d6
α-Vitamin E-d₆ is the deuterium labeled α-Vitamin E[1].

HY-W020044S1

*DL-alpha-Tocopherol-d9*
DL-alpha-Tocopherol-d₉ is the deuterium labeled DL-alpha-Tocopherol[1]. DL-alpha-Tocopherol is a synthetic vitamin E, with antioxidation effect. DL-alpha-Tocopherol protects human skin fibroblasts against the cytotoxic effect of UVB[2].

HY-N6710S

α-Zearalenol-d4
α-Zearalenol-d4 is a deuterated labeled α-Zearalenol . α-Zearalenol is a Mycotoxin with high affinity for the estrogen receptors (ER), α-Zearalenol is the derivative of zearalenone (ZEN), causes reproductive disorders in animals, due to its xenoestrogenic effects .

HY-N7264S

7α-Hydroxycholesterol-d7
7α-Hydroxycholesterol-d₇ is the deuterium labeled 7α-Hydroxycholesterol. 7α-Hydroxycholesterol is a cholesterol oxide and is formed by both enzymatic and non-enzymatic oxidation. 7α-Hydroxycholesterol can be used as a biomarker for lipid peroxidation[1][2][3].

HY-128417S

alpha-D-glucose-d12
alpha-D-glucose-d₁₂ is the deuterium labeled alpha-D-glucose. alpha-D-glucose is an endogenous metabolite.

HY-133890AS

Tauro-α-muricholic acid-d4 sodium
Tauro-α-muricholic acid-d₄ (sodium) is the deuterium labeled Tauro-α-muricholic acid sodium[1].

HY-132649S

α-Cholestane-d4
α-Cholestane-d₄ is the deuterium labeled α-Cholestane[1].

HY-134670S1

α-Hydroxymetoprolol-d7
α-Hydroxymetoprolol-d₇ is the deuterium labeled α-Hydroxymetoprolol[1].

HY-Y0245S

α-Cyanopyridine-d4
α-Cyanopyridine-d₄ is the deuterium labeled α-Cyanopyridine[1].

HY-151892S

Glimepiride-d4(phenylethyl-α,α,β,β-d4)(cis/trans)
Glimepiride-d₄(phenylethyl-α,α,β,β-d₄)(cis/trans) is the deuterium labeled [1].

HY-128417S1

Alpha-D-glucose-13C
Alpha-D-glucose- ¹³C is the ¹³C labeled alpha-D-glucose. alpha-D-glucose is an endogenous metabolite[1].

HY-128417S3

alpha-D-glucose-d7
alpha-D-glucose-d₇ is the deuterium labeled alpha-D-glucose[1]. alpha-D-glucose is an endogenous metabolite.

HY-W020044S

*DL-alpha-Tocopherol-13C3*
DL-alpha-Tocopherol- ¹³C₃ is the ¹³C-labeled DL-alpha-Tocopherol. DL-alpha-Tocopherol is a synthetic vitamin E, with antioxidation effect. DL-alpha-Tocopherol protects human skin fibroblasts against the cytotoxic effect of UVB[1].

HY-118566S

5α-Androstenone-d4
5α-Androstenone-d₄ is the deuterium labeled 5α-Androstenone[1].

HY-133970S

5α-Cholestane-d6
5α-Cholestane-d₆ is the deuterium labeled 5α-Cholestane[1].

HY-133970S1

5α-Cholestane-d2
5α-Cholestane-d₂ is the deuterium labeled 5α-Cholestane[1].

HY-W145656S

α,β-Trehalose-d2
α,β-Trehalose-d₂ is the deuterium labeled α,β-Trehalose[1].

HY-115433S1

α-Muricholic acid-d4
α-Muricholic acid-d₄ is the deuterium labeled α-Muricholic acid. α-Muricholic acid is the most abundant primary bile acid in rodents[1][2].

HY-115433S

α-Muricholic acid-d5
α-Muricholic acid-d₅ is the deuterium labeled α-Muricholic acid. α-Muricholic acid is the most abundant primary bile acid in rodents[1][2].

HY-N0683S

α-Vitamin E-13C6
α-Vitamin E- ¹³C₆ is the ¹³C-labeled α-Vitamin E. α-Vitamin E ((+)-α-Tocopherol), a naturally occurring vitamin E form, is a potent antioxidant[1][2].

HY-N0683S1

α-Vitamin E-13C3
α-Vitamin E- ¹³C₃ is the ¹³C-labeled α-Vitamin E. α-Vitamin E ((+)-α-Tocopherol), a naturally occurring vitamin E form, is a potent antioxidant[1][2].

HY-146784S

7α,24(R/S)-Dihydroxycholesterol-d7
7α,24(R/S)-Dihydroxycholesterol-d₇ is deuterium labeled 7α,24(R/S)-Dihydroxycholesterol.

HY-146787S

7α,24(R/S)-Dihydroxycholestenone-d7
7α,24(R/S)-Dihydroxycholestenone-d₇ is deuterium labeled 7α,24(R/S)-Dihydroxycholestenone.

HY-N5142S

α-Terpineol-d3
α-Terpineol-d₃ is the deuterium labeled α-Terpineol[1]. α-Terpineol is isolated from Eucalyptus globulus Labill, exhibits strong antimicrobial activity against periodontopathic and cariogenic bacteria[2].α-Terpineol possesses antifungal activity against T. mentagrophytes, and the activity might lead to irreversible cellular disruption[2].

HY-W010249S

D-α-Phenyl-glycine-d5
D-α-Phenyl-glycine-d₅ is the deuterium labeled D-α-Phenyl-glycine.

HY-W017406S

L-α-Phenyl-glycine-d5
L-α-Phenyl-glycine-d₅ is the deuterium labeled L-α-Phenyl-glycine.

HY-N0728S2

α-Linolenic acid-d14
α-Linolenic acid-d₁₄ is the deuterium labeled α-Linolenic acid. α-Linolenic acid, isolated from seed oils, is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer[1].

HY-N0728S

α-Linolenic acid-d5
α-Linolenic acid-d₅ is the deuterium labeled α-Linolenic acid. α-Linolenic acid, isolated from seed oils, is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer[1].

HY-N8847S

α-Ionone-13C3
α-Ionone- ¹³C₃ is the ¹³C labeled α-Ionone[1].

HY-146638S

5α-Pregnan-11β,17α,21-triol-3,20-dione-1,2,4,5-d4
5α-Pregnan-11β,17α,21-triol-3,20-dione-1,2,4,5-d₄ is the deuterium labeled 5α-Pregnan-11β,17α,21-triol-3,20-dione-1,2,4,5[1].

HY-144241S

*DL-Alpha-tocopherol nicotinate-d9*
DL-Alpha-tocopherol nicotinate-d₉ is the deuterium labeled DL-Alpha-tocopherol nicotinate[1].

HY-150718S

α-Ketoisohexanoic acid-d3 sodium
α-Ketoisohexanoic acid-d₃ (sodium) is the deuterium labeled α-Ketoisohexanoic acid sodium[1].

HY-154758S

*6-Alpha-Methyl-Cortisol-d4*
6-Alpha-Methyl-Cortisol-d₄ is deuterated labeled 6-Alpha-Methyl-Cortisol.

HY-154759S

*6-Alpha-Methyl-Prednisolone-d4*
6-Alpha-Methyl-Prednisolone-d₄ is deuterated labeled 6-Alpha-Methyl-Prednisolone.

HY-156250S

7α-Methylthiol spironolactone-d5
7α-Methylthiol spironolactone-d₅ is deuterated labeled 7α-Methylthiol spironolactone.

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Species:	Human (557) Porcine (2) Rhesus Macaque (23) Bovine (7) Rat (57) Cynomolgus (43) E.coli (3) Rabbit (2) Canine (20) Pig (2) Virus (2) Marmoset (1) Mouse (188) Sheep (2) Equine (1) Staphylococcus aureus (1)
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Source:	HEK293 (574) E. coli Cell-free (3) CHO (15) Sf9 insect cells (2) P. pastoris (31) Sf9 insect cells (66) E. coli (240)


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