Search Result

Results for "

NSG mouse,

" in MedChemExpress (MCE) Product Catalog:

By Targets:	11β-HSD (9) 5 alpha Reductase (1) 5-HT Receptor (9) Acyltransferase (4) ADC Antibody (1) ADC Cytotoxin (2) Adenosine Receptor (7) Adenylate Cyclase (2) Adiponectin Receptor (2) Adrenergic Receptor (17) Akt (11) Aldehyde Dehydrogenase (ALDH) (3) Amine N-methyltransferase (2) Amino Acid Derivatives (2) Aminoacyl-tRNA Synthetase (1) Aminopeptidase (1) AMPK (7) Amylin Receptor (3) Amyloid-β (13) Anaplastic lymphoma kinase (ALK) (3) Androgen Receptor (10) Angiotensin Receptor (4) Angiotensin-converting Enzyme (ACE) (1) Antibiotic (26) AP-1 (1) Apelin Receptor (APJ) (4) Apical Sodium-Dependent Bile Acid Transporter (3) Apoptosis (165) Aquaporin (1) Arrestin (1) Aryl Hydrocarbon Receptor (3) Atg8/LC3 (5) ATM/ATR (1) ATP Citrate Lyase (1) ATP Synthase (1) ATTECs (2) AUTACs (1) Autophagy (50) Bacterial (66) Bcl-2 Family (7) BCL6 (1) Bcr-Abl (2) Beta-lactamase (1) Beta-secretase (6) Biochemical Assay Reagents (29) Bombesin Receptor (3) Bradykinin Receptor (4) BRK (1) Btk (8) c-Fms (6) c-Kit (2) c-Met/HGFR (7) c-Myc (3) C-type Lectin-like Receptor (CTLR) (1) Calcium Channel (9) Calmodulin (2) CaMK (2) Cannabinoid Receptor (9) Carbonic Anhydrase (6) Carboxypeptidase (1) Casein Kinase (4) Caspase (14) CaSR (1) Cathepsin (4) CCR (12) CD19 (6) CD2 (1) CD20 (4) CD22 (2) CD276/B7-H3 (1) CD28 (6) CD3 (11) CD38 (3) CD47 (5) CD6 (1) CDK (27) Ceramidase (2) CFTR (1) CGRP Receptor (4) Chemerin Receptor (2) Chloride Channel (3) Cholecystokinin Receptor (5) Cholinesterase (ChE) (9) ClpP (2) Complement System (9) COX (14) CRAC Channel (1) CRFR (7) CTLA-4 (1) Cuproptosis (2) CXCR (9) Cyclic GMP-AMP Synthase (3) Cyclophilin (1) Cytochrome P450 (10) DAGL (2) Dan family (1) Dengue virus (13) Deubiquitinase (3) Dihydrofolate reductase (DHFR) (2) Dihydroorotate Dehydrogenase (2) Dipeptidyl Peptidase (5) DNA Alkylator/Crosslinker (1) DNA Methyltransferase (1) DNA/RNA Synthesis (23) Dopamine Receptor (9) Dopamine Transporter (1) Drug Derivative (4) Drug Metabolite (3) Drug-Linker Conjugates for ADC (4) Dynamin (1) DYRK (3) E-Selectin (1) E1/E2/E3 Enzyme (3) E3 Ligase Ligand-Linker Conjugates (1) EAAT (1) EBI2/GPR183 (3) EBV (2) EGFR (14) Elastase (2) ELOVL (1) Endogenous Metabolite (89) Endothelin Receptor (3) Ephrin Receptor (1) Epigenetic Reader Domain (12) Epoxide Hydrolase (9) ERK (14) Estrogen Receptor/ERR (12) FAAH (3) FABP (1) Factor Xa (1) FAK (6) Farnesyl Transferase (1) FATP (1) Fatty Acid Synthase (FASN) (5) Ferroptosis (15) FGFR (4) Filovirus (1) FLAP (2) Flavivirus (14) FLT3 (5) Fluorescent Dye (12) Formyl Peptide Receptor (FPR) (1) FOXO (1) Free Fatty Acid Receptor (4) Fungal (22) FXR (6) G protein-coupled Bile Acid Receptor 1 (1) G-quadruplex (1) G2A (GPR132) (1) GABA Receptor (14) Galectin (3) GCGR (4) Gli (1) GLP Receptor (3) Glucocorticoid Receptor (6) Glucokinase (2) Glucosylceramide Synthase (GCS) (2) GLUT (2) Glutaminase (4) Glutathione Peroxidase (2) Glycoprotein VI (1) Glycosidase (4) GlyT (2) GnRH Receptor (1) GPR119 (3) GPR171 (1) GPR52 (1) GSK-3 (6) Guanylate Cyclase (3) HBV (5) HDAC (17) Hedgehog (1) Herbicide (1) HIF/HIF Prolyl-Hydroxylase (3) Hippo (MST) (1) Histamine Receptor (14) Histone Acetyltransferase (3) Histone Demethylase (6) Histone Methyltransferase (9) HIV (10) HIV Protease (1) HMG-CoA Reductase (HMGCR) (2) HOXA (1) HSP (39) HSV (7) Huntingtin (2) HuR (1) Hydroxycarboxylic Acid Receptor (HCAR) (2) ICMT (1) IFNAR (5) IGF-1R (1) iGluR (6) IKK (5) Indoleamine 2,3-Dioxygenase (IDO) (2) Influenza Virus (7) Insecticide (5) Insulin Receptor (3) Integrin (15) Interleukin Related (42) IRAK (8) Isotope-Labeled Compounds (41) Itk (1) JAK (9) JNK (9) Keap1-Nrf2 (8) Kinesin (2) Kisspeptin Receptor (2) Lactate Dehydrogenase (2) LAG-3 (3) LDLR (2) Leukotriene Receptor (2) Lipocalin Family (1) Liposome (5) Lipoxygenase (3) LPL Receptor (8) LXR (1) mAChR (4) MAGL (9) MALT1 (2) MAP3K (1) MAP4K (1) MAPKAPK2 (MK2) (1) MCHR1 (GPR24) (6) MDM-2/p53 (7) MEK (6) Melanocortin Receptor (13) Melatonin Receptor (4) MetAP (1) mGluR (2) MHC (2) MicroRNA (5) Microtubule/Tubulin (13) Mineralocorticoid Receptor (1) Mitochondrial Metabolism (9) Mitophagy (6) Mixed Lineage Kinase (3) MMP (14) MNK (1) Molecular Glues (5) Monoamine Oxidase (11) Monoamine Transporter (1) Monocarboxylate Transporter (1) mTOR (6) Mucin (1) MyD88 (2) N-myristoyltransferase (1) nAChR (2) NADPH Oxidase (1) NAMPT (2) Necroptosis (4) NEKs (2) Neprilysin (3) Neurokinin Receptor (2) Neuropeptide FF Receptor (1) Neuropeptide Y Receptor (16) Neurotensin Receptor (5) NF-κB (27) NO Synthase (11) NOD-like Receptor (NLR) (12) Notch (4) Nuclear Factor of activated T Cells (NFAT) (3) Nuclear Hormone Receptor 4A/NR4A (1) Nucleoside Antimetabolite/Analog (4) Opioid Receptor (8) Orexin Receptor (OX Receptor) (10) Organoid (7) Orphan Receptor (2) Oxytocin Receptor (3) P-glycoprotein (1) P2X Receptor (6) P2Y Receptor (5) p38 MAPK (13) p62 (4) PACAP Receptor (1) PAI-1 (1) PAK (3) Parasite (34) PARP (7) PCSK9 (3) PD-1/PD-L1 (21) PDGFR (1) PDHK (1) PDI (3) PDK-1 (1) PERK (1) PGE synthase (3) Phosphatase (16) Phosphodiesterase (PDE) (12) Phospholipase (4) PI3K (8) PI4K (2) Piezo Channel (1) Pim (1) PIN1 (1) PINK1/Parkin (2) PKA (3) PKC (6) PKD (1) Platelet-activating Factor Receptor (PAFR) (1) Polo-like Kinase (PLK) (2) Poly(ADP-ribose) Glycohydrolase (PARG) (1) Porcupine (1) Potassium Channel (18) PPAR (20) Prolyl Endopeptidase (PREP) (3) Prostaglandin Receptor (20) PROTAC Linkers (4) PROTACs (26) Protease Activated Receptor (PAR) (4) Proteasome (1) Protein Arginine Deiminase (3) PSMA (1) PTHR (5) Pyk2 (2) Pyroptosis (3) Pyruvate Kinase (2) RABV (1) Radionuclide-Drug Conjugates (RDCs) (4) Raf (5) RANKL/RANK (1) RAR/RXR (3) Ras (11) Reactive Oxygen Species (32) RET (1) Reverse Transcriptase (4) RGS Protein (1) RIP kinase (7) ROCK (2) ROR (10) ROS Kinase (4) RSV (3) Salt-inducible Kinase (SIK) (1) SARS-CoV (12) Ser/Thr Protease (2) SGLT (6) SHMT (1) SHP2 (4) Sigma Receptor (2) Sirtuin (8) Small Interfering RNA (siRNA) (727) Smo (4) SOD (1) Sodium Channel (7) Somatostatin Receptor (10) Src (3) STAT (16) Stearoyl-CoA Desaturase (SCD) (4) STING (11) Survivin (1) Syk (2) TAM Receptor (4) Taste Receptor (2) Tau Protein (5) Telomerase (2) TGF-beta/Smad (10) TGF-β Receptor (3) Thymidylate Synthase (2) Thyroid Hormone Receptor (4) Tie (2) Tim3 (1) TNF Receptor (34) Toll-like Receptor (TLR) (28) Topoisomerase (4) Trace Amine-associated Receptor (TAAR) (3) Transferrin Receptor (2) Transmembrane Glycoprotein (10) Trk Receptor (4) TRP Channel (9) Tyrosinase (4) URAT1 (2) Urea Transporter (2) Urotensin Receptor (5) Vasopressin Receptor (4) VD/VDR (1) VDAC (1) VEGFR (7) Virus Protease (8) Wnt (14) Xanthine Oxidase (2) YAP (9) α-synuclein (5) β-catenin (8) β-glucuronidase (1) γ-secretase (2)
By Research Areas:	Cancer (644) Cardiovascular Disease (122) Endocrinology (70) Infection (187) Inflammation/Immunology (468) Metabolic Disease (258) Neurological Disease (344)
Click Chemistry:	Alkynes (4)
Oligonucleotides:	miRNA mimics (1) Decoy ODNs (1) miRNA antagomirs (1) mRNA (2) miRNA inhibitors (1) Antisense Oligonucleotides (5) siRNAs (705) miRNA agomirs (1) MicroRNAs (4) Aptamers (4) Pre-designed siRNA Sets (698) CpG ODNs (1) Cationic Lipids (3)

2456

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

250

Peptides

MCE Kits

405

Inhibitory Antibodies

175

Natural
Products

2051

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

725

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P99132

*Anti-Mouse* CTLA-4 Antibody (9D9)**	CTLA-4	Inflammation/Immunology
Anti-Mouse CTLA-4 Antibody is an anti-mouse CTLA-4 IgG2b antibody inhibitor derived from host mouse.

HY-P990110

*Lecanemab (Mouse* IGG2a)** Mab158	Amyloid-β	Neurological Disease
Lecanemab (Mouse IGG2a) is a monoclonal antibody that targets soluble β-amyloid and has the potential to reduce cognitive decline. The variable region of Lecanemab (Mouse IGG2a) is consistent with that of Lecanemab, while the constant region is of Mouse IGG2a sequence. Lecanemab (Mouse IGG2a) holds promise for research in the field of Alzheimer's disease .

HY-RS09593

NSG1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
NSG1 Human Pre-designed siRNA Set A contains three designed siRNAs for NSG1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

NSG1 Human Pre-designed siRNA Set A NSG1 Human Pre-designed siRNA Set A

HY-RS09594

NSG2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
NSG2 Human Pre-designed siRNA Set A contains three designed siRNAs for NSG2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

NSG2 Human Pre-designed siRNA Set A NSG2 Human Pre-designed siRNA Set A

HY-P990147

*Anti-Mouse* VEGFR-2 Antibody (DC101-Mouse IgG2a)**	VEGFR	Others
Anti-Mouse VEGFR-2 Antibody (DC101-CP132) is a mouse-derived IgG2a, κ type antibody inhibitor, targeting to mouse VEGFR-2.

HY-P990793

*Anti-Mouse* CD28 Antibody (D665)**	CD28	Others
Anti-Mouse CD28 Antibody (D665) is a kind of mouse IgG1 kappa in vivo mouse antibody, targeting to CD28. The recommend isotype control of Anti-Mouse CD28 Antibody (D665): Mouse IgG1 kappa, Isotype Control (HY-P99977).

HY-P99145A

*Anti-Mouse* PD-L1/B7-H1 Antibody (10F.9G2-Mouse IgG1)**	PD-1/PD-L1	Others
Anti-Mouse PD-L1/B7-H1 Antibody (10F.9G2-Mouse IgG1) is a mouse-derived IgG1, κ type antibody inhibitor, targeting to mouse PD-L1/B7-H1.

HY-P990149

*Anti-Mouse/Human TYRP1 Antibody (TA99)*	Tyrosinase	Others
Anti-Mouse/Human TYRP1 Antibody (TA99) is a mouse-derived IgG2a, κ type antibody inhibitor, targeting to mouse/human TYRP1.

HY-P990303

*Anti-Mouse* 2C TCR Antibody (1B2)**	Nuclear Factor of activated T Cells (NFAT)	Others
Anti-Mouse 2C TCR Antibody (1B2) is a mouse-derived IgG1 type antibody inhibitor, targeting to mouse 2C TCR.

HY-P990265

*Anti-Mouse* CD69 Antibody (CD69.2.2)**	C-type Lectin-like Receptor (CTLR)	Others
Anti-Mouse CD69 Antibody (CD69.2.2) is a mouse-derived IgG1, κ type antibody inhibitor, targeting to mouse CD69.

HY-P99133

*Anti-Mouse* Fas Ligand Antibody (MFL3)**	Fatty Acid Synthase (FASN)	Inflammation/Immunology
Anti-Mouse Fas Ligand Antibody is an anti-mouse Fas Ligand IgG antibody inhibitor derived from host Armenian Hamster.

HY-P99136

*Anti-Mouse* IFN gamma Antibody (H22)**	IFNAR	Inflammation/Immunology
Anti-Mouse IFN gamma Antibody is an anti-mouse IFN gamma IgG antibody inhibitor derived from host Armenian Hamster.

HY-P99123

*Anti-Mouse* CD28 Antibody (37.51)**	CD28	Inflammation/Immunology
Anti-Mouse CD28 Antibody is an anti-mouse CD28 IgG antibody inhibitor derived from the host Syrian Hamster.

HY-P99144

*Anti-Mouse* PD-1 Antibody (RMP1-14)** 4 Publications Verification	PD-1/PD-L1	Inflammation/Immunology
Anti-Mouse PD-1 Antibody is an anti-mouse PD-1 IgG2a antibody inhibitor.

HY-P990273

*Anti-Mouse* CD38 Antibody (NIMR5)**	CD38	Others
Anti-Mouse CD38 Antibody (NIMR5) is a rat-derived IgG2a, κ type antibody inhibitor, targeting to mouse CD38.

HY-P99976

*Anti-Mouse* CD19 Antibody (1D3)**	CD19	Cancer
Anti-Mouse CD19 Antibody (1D3) is an anti-mouse CD19 IgG2a antibody inhibitor.

HY-P99999

*Anti-Mouse* CD4 Antibody (YTS 191)**	HIV	Infection
Anti-Mouse CD4 Antibody (YTS 191) is anti-mouse CD4 IgG2b antibody inhibitor derived from host Rat.

HY-P99124

*Anti-Mouse* CD3 Antibody (17A2)** 1 Publications Verification	CD3	Inflammation/Immunology
Anti-Mouse CD3 Antibody is an anti-mouse CD3 IgG2b antibody inhibitor derived from the host Rat.

HY-P990251

*Anti-Human/Mouse* denatured collagen type-I Antibody (XL313)**	MMP	Others
Anti-Human/Mouse denatured collagen type-I Antibody (XL313) is a mouse-derived IgG1, κ type antibody inhibitor, targeting to human/mouse denatured collagen type-I.

HY-P99148

*Anti-Mouse* TNF alpha Antibody (TN3-19.12)**	TNF Receptor	Inflammation/Immunology
Anti-Mouse TNF alpha Antibody is an anti-mouse TNF alpha IgG antibody inhibitor derived from host Rat.

HY-P990272

*Anti-Mouse* CD3ε Antibody (KT3)**	CD3	Inflammation/Immunology
Anti-Mouse CD3ε Antibody (KT3) is a rat-derived IgG2a type antibody inhibitor, targeting to mouse CD3ε.

HY-P99149

*Anti-Mouse* TNFR2 Antibody (TR75-54.7)**	TNF Receptor	Inflammation/Immunology
Anti-Mouse TNFR2 Antibody is an anti-mouse TNFR2 IgG antibody inhibitor derived from host Armenian Hamster.

HY-P99138

*Anti-Mouse* IL-1a Antibody (ALF-161)**	Integrin	Inflammation/Immunology
Anti-Mouse IL-1a Antibody is an anti-mouse IL-1a IgG1 antibody inhibitor derived from host Armenian Hamster.

HY-P99139

*Anti-Mouse* IL-1b Antibody (B122)**	Interleukin Related	Inflammation/Immunology
Anti-Mouse IL-1b Antibody is an anti-mouse IL-1b IgG antibody inhibitor derived from host Armenian Hamster.

HY-P990152

*Anti-Mouse* TIM-4 Antibody (RMT4-54)**	Akt ERK	Others
Anti-Mouse TIM-4 Antibody (RMT4-54) is a rat-derived IgG2a, κ type antibody inhibitor, targeting to mouse TIM-4.

HY-P99134

*Anti-Mouse* GM-CSF Antibody (MP1-22E9)**	c-Fms	Inflammation/Immunology
Anti-Mouse GM-CSF Antibody is an anti-mouse GM-CSF IgG2a antibody inhibitor derived from host Rat.

HY-P99127

*Anti-Mouse* CD54 Antibody (YN1/1.7.4)**	Integrin	Inflammation/Immunology
Anti-Mouse CD54 Antibody is an anti-mouse CD54 IgG2b antibody inhibitor derived from host Rat.

HY-P99141

*Anti-Mouse* LAG-3 Antibody (C9B7W)**	LAG-3	Inflammation/Immunology
Anti-Mouse LAG-3 is an anti-mouse LAG-3 IgG1 antibody inhibitor derived from host Rat.

HY-P990792

*Anti-Mouse* CD4 Antibody (GK1.5)**	Transmembrane Glycoprotein	Others
Anti-Mouse CD4 Antibody (GK1.5) is a kind of rat IgG2b kappa in vivo mouse antibody, targeting to CD4. The recommend isotype control of Anti-Mouse CD4 Antibody (GK1.5): Rat IgG2b kappa, Isotype Control (HY-P990682).

HY-P99140

*Anti-Mouse* IL-1R Antibody (JAMA-147)**	Interleukin Related	Inflammation/Immunology
Anti-Mouse IL-1R Antibody is an anti-mouse IL-1R IgG2b antibody inhibitor derived from host Armenian Hamster.

HY-P990131

*Anti-Mouse* CD47/IAP Antibody (MIAP301)**	CD47	Others
Anti-Mouse CD47/IAP Antibody (MIAP301) is a rat-derived IgG2a, κ type antibody inhibitor, targeting to mouse CD47/IAP.

HY-P990304

*Anti-Mouse* 4-1BBL/CD137L Antibody (TKS-1)**	TNF Receptor	Others
Anti-Mouse 4-1BBL/CD137L Antibody (TKS-1) is a mouse-derived inhibitor that is an IgG2a, κ antibody against mouse 4-1BBL/CD137L.

HY-P990820

*Anti-Mouse* TIM-4 Antibody (RMT4-53)**	Mitochondrial Metabolism	Others
Anti-Mouse TIM-4 Antibody (RMT4-53) is a kind of rat IgG2b kappa in vivo mouse antibody, targeting to TIM-4. The recommend isotype control of Anti-Mouse TIM-4 Antibody (RMT4-53): Rat IgG2b kappa, Isotype Control (HY-P990682).

HY-P990211

*Anti-Mouse* IL-6R Antibody (15A7)**	Interleukin Related	Others
Anti-Mouse IL-6R Antibody (15A7) is a rat-derived IgG2b, κ type antibody inhibitor, targeting to mouse IL-6R.

HY-P990267

*Anti-Mouse* CD45RB Antibody (MB23G2)**	Transmembrane Glycoprotein	Others
Anti-Mouse CD45RB Antibody (MB23G2) is a rat-derived IgG2a, κ type antibody inhibitor, targeting to mouse CD45RB.

HY-P990125

*Anti-Mouse* (CSF1R/CD115) Antibody (AFS98)**	c-Fms	Others
Anti-Mouse CSF1R (CD115) Antibody (AFS98) is a rat-derived IgG2a, κ type antibody inhibitor, targeting to mouse CSF1R.

HY-P99137

*Anti-Mouse* IFNAR1 Antibody (MAR1-5A3)**	IFNAR	Inflammation/Immunology
Anti-Mouse IFNAR1 Antibody (MAR1-5A3) is a neutralizing antibody of IFNAR1. Anti-Mouse IFNAR1 Antibody (MAR1-5A3) reacts with IFNAR1 and inhibits IFNAR1 signaling in vitro and in vivo. Mouse IgG1 kappa, Isotype Control (HY-P99977) is the isotype control of Anti-Mouse IFNAR1 Antibody (MAR1-5A3) .

HY-P990004

*Anti-Mouse* TIM-3 Antibody (B8.2C12)**	Tim3	Cancer
Anti-Mouse TIM-3 Antibody (B8.2C12) is an anti-mouse TIM-3 antibody inhibitor. Anti-Mouse TIM-3 Antibody (B8.2C12) is a rat IgG1κ subtype antibody .

HY-P990001

*Anti-Mouse* IL-10 Antibody (JES5-2A5)**	Interleukin Related	Inflammation/Immunology
Anti-Mouse IL-10 Antibody (JES5-2A5) is an IgG1 antibody inhibitor against mouse IL-10. Derived from rat.

HY-P990002

*Anti-Mouse* CD117/c-Kit Antibody (2B8)**	c-Kit	Cancer
Anti-Mouse CD117/c-Kit Antibody (2B8) is an IgG2b antibody inhibitor against mouse CD117. Derived from rat.

HY-P990280

*Anti-Mouse* CD27 Antibody (RM27-3E5)**	TNF Receptor	Others
Anti-Mouse CD27 Antibody (RM27-3E5) is a rat-derived IgG2a, κ type antibody inhibitor, targeting to mouse CD27.

HY-P990207

*Anti-Mouse/Human Integrin β7 Antibody (FIB504)*	Integrin	Others
Anti-Mouse/Human Integrin β7 Antibody (FIB504) is a rat-derived IgG2a, κ type antibody inhibitor, targeting to mouse/human Integrin β7.

HY-P990270

*Anti-Mouse* CD40L/CD154 (D265A) Antibody (MR-1)**	TNF Receptor	Others
Anti-Mouse CD40L/CD154 (D265A) Antibody (MR-1) is a mouse-derived IgG1, κ type antibody inhibitor, targeting to mouse CD40L/CD154.

HY-P99146

*Anti-Mouse* TCR gamma/delta Antibody (UC7-13D5)**	CD3	Inflammation/Immunology
Anti-Mouse TCR gamma/delta Antibody is an anti-mouse TCR gamma/delta IgG antibody inhibitor derived from host Armenian Hamster.

HY-P990212

*Anti-Mouse* IL-6 Antibody (MP5-20F3)**	Interleukin Related	Others
Anti-Mouse IL-6 Antibody (MP5-20F3) is a rat-derived IgG1, κ type antibody inhibitor, targeting to mouse IL-6.

HY-P990217

*Anti-Mouse* IL-23 p19 Antibody (G23-8)**	Interleukin Related	Others
Anti-Mouse IL-23 p19 Antibody (G23-8) is a rat-derived IgG1, κ type antibody inhibitor, targeting to mouse IL-23 p19.

HY-P990802

*Anti-Mouse* CD3ε Antibody (145-2C11)**	CD3	Inflammation/Immunology
Anti-Mouse CD3ε Antibody (145-2C11) is a kind of Armenian hamster IgG1 in vivo mouse antibody, targeting to CD3ε. The recommend isotype control of Anti-Mouse CD3ε Antibody (145-2C11): Armenian hamster IgG, Isotype Control (HY-P990305).

HY-P990169

*Anti-Mouse/Human phosphorylated PD-1/CD279 Antibody (407.6G12)*	PD-1/PD-L1	Others
Anti-Mouse/Human phosphorylated PD-1/CD279 Antibody (407.6G12) is a mouse-derived IgG2a, κ type antibody inhibitor, targeting to mouse/human phosphorylated PD-1/CD279.

HY-P990129

*Anti-Mouse* CD71/TfR1 Antibody (8D3)**	Transferrin Receptor	Others
Anti-Mouse CD71/TfR1 Antibody (8D3) is a rat-derived IgG2a type antibody inhibitor, targeting to mouse CD71/TfR1.

HY-P990134

*Anti-Mouse* CD40L/CD154 Antibody (MR-1)**	TNF Receptor	Others
Anti-Mouse CD40L/CD154 Antibody (MR-1) is a Armenian hamster-derived IgG type antibody inhibitor, targeting to mouse CD40L/CD154.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-P1067

*Enterostatin(human,mouse,rat)*	Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Enterostatin, human, mouse, rat is a pentapeptide that reduces fat intake.

HY-N0370

Bergapten 4 Publications Verification 5-Methoxypsoralen	Structural Classification other families Classification of Application Fields Source classification Coumarins Phenylpropanoids Plants Disease Research Fields Cancer	Cytochrome P450 Autophagy
Bergapten is a natural anti-inflammatory and anti-tumor agent. Bergapten is inhibitory towards mouse and human CYP isoforms.

HY-N4300

4'-O-Methylochnaflavone 1 Publications Verification	Structural Classification Caprifoliaceae Ginkgoaceae Classification of Application Fields Lonicera japonica Thunb. Source classification Plants Ginkgo biloba Flavonoids Phenols Polyphenols Biflavones Inflammation/Immunology Disease Research Fields	Others
4'-O-Methylochnaflavone is a biflavonoid isolated from Lonicera japonica, suppresses mouse lymphocyte proliferation .

HY-N0204

Pulchinenoside A Anemoside A3	Triterpenes Structural Classification Classification of Application Fields Terpenoids Source classification Ranunculaceae Other Diseases Plants Disease Research Fields Pulsatilla chinensis (Bunge) Regel	iGluR
Pulchinenoside A is a natural triterpenoid saponin that enhances synaptic plasticity in the adult mouse hippocampus and facilitates spatial memory in adult mice.

HY-N7935

Procyanidin B5	Structural Classification Aronia melanocarpa Source classification Rosaceae Phenols Polyphenols Plants	Reactive Oxygen Species
Procyanidin B5 is an antioxidant agent with an IC₅₀ of 0.1 mM in mouse liver homogenate lipid peroxidation assay .

HY-N3595

Cleomiscosin A	Structural Classification Monophenols Classification of Application Fields Source classification Lignans Phenols Euphorbiaceae Phenylpropanoids Plants Macaranga adenantha Gagnep. Inflammation/Immunology Disease Research Fields	TNF Receptor
Cleomiscosin A is a coumarino-lignoid from branch of Macaranga adenantha. Cleomiscosin A is active against TNF-alpha secretion of the mouse peritoneal macrophages .

HY-P2792

Beauveriolide III	Natural Products Microorganisms Classification of Application Fields Source classification Metabolic Disease Disease Research Fields	Others
Beauveriolide III is an inhibitor of lipid droplet formation in mouse macrophages .

HY-N3775

Dodoviscin I	Structural Classification Flavonoids Flavones Dodonaea viscosa (L.) Jacq. Source classification Sapindaceae Plants	ERK
Dodoviscin I is an adipogenesis agent that increases triglyceride content in 3T3L1 mouse fibroblasts .

HY-126813

Concanamycin C	Structural Classification Natural Products Microorganisms Source classification	Fungal
Concanamycin C inhibits proliferation of mouse splenic lymphocytes. Concanamycin C exhibits antibiotic effects against fungal and yeast .

HY-148614

Isocaproaldehyde 4-Methylpentanal; 4-Methylvaleraldehyde	Structural Classification Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Others
Isocaproaldehyde is a product of side-chain cleavage of cholesterol. Isocaproaldehyde is an endogenous specific substrate of mouse vas deferens protein (MVDP) .

HY-N11494

Dauricumine	Structural Classification Alkaloids Source classification Plants Menispermaceae Menispermum dauricum Alkaloid Dimers	NF-κB
Dauricumine is a chlorinated alkaloid that inhibits NF-κB ligand-induced differentiation of mouse bone marrow-derived macrophages into multinucleated osteoclasts .

HY-N0648

Monotropein	Structural Classification Iridoids Classification of Application Fields Terpenoids Pyrola calliantha H. Andr. Source classification Rubiaceae Pyrolaceae Plants Morinda officinalis How Inflammation/Immunology Disease Research Fields	Others
Monotropein is an iridoid glycoside isolated Morinda officinalis. Monotropein inhibits the expression of inflammatory mediators in dextran sulfate sodium (DSS)-induced colitis mouse model .

HY-W587489

RL-603	Structural Classification Natural Products Source classification Endogenous metabolite	Drug Metabolite
RL-603 is the metabolite of Anagrelide (HY-B0523). RL-603 exhibits platelet-lowering activity in mouse model .

HY-P1987

Mast cell degranulating peptide (28-49)	Structural Classification Natural Products Animals Source classification	Calcium Channel
Mast cell degranulating peptide (28-49) is a depolarizing agent from bee venom, it can raise the content of cGMP level in mouse cerebellar slices .

HY-117180

Diastovaricin I 30-Hydroxy-naphthomycin C	Structural Classification Macrolide Antibiotics Antibiotics Source classification Endogenous metabolite	Antibiotic
Diastovaricin I (30-Hydroxy-naphthomycin C) is an antibiotic without exhibiting antimicrobial activity. Diastovaricin I induces differentation of mouse Friend cell .

HY-N1403

Tigogenin	Structural Classification Classification of Application Fields Source classification Metabolic Disease Agavaceae Plants Agave sisalana Perr. ex Engelm. Disease Research Fields Steroids	Others
Tigogenin, one of steroidal sapogenins, is widely used for synthesizing steroid agents. Tigogenin inhibits adipocytic differentiation and induces osteoblastic differentiation in mouse bone marrow stromal cells .

HY-N10237

Mycestericin C	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields Cancer	Others
Mycestericin C is a compound isolated from the culture broth of Mycelia sterilia ATCC 20349. Mycestericin C suppresses the proliferation of lymphocytes in the mouse allogeneic mixed lymphocyte reaction .

HY-N12431

Machilin A	Structural Classification Machilus thunbergii Sieb. et Zucc. Source classification Lignans Phenylpropanoids Plants Lauraceae	Others
Machilin A is a lignan isolated from the methanolic extract of Phoebe bark. Machilin A inhibits melanin biosynthesis in B-16 mouse melanoma cells with an IC₅₀ of 39.9 μM.

HY-158925

Conglobatin C1	Structural Classification Microorganisms Macrolide Antibiotics Antibiotics Source classification	Endogenous Metabolite
Conglobatin C1 is a bacterial metabolite and has anticancer activity. Conglobatin C1 is cytotoxic to NS-1 mouse myeloma cells (IC₅₀ = 1.05 μg/mL) .

HY-17035

Doramectin 4 Publications Verification	Infection Structural Classification Microorganisms Antibiotics Source classification Anti-parasitic Antibacterial Disease Research Disease Research Fields Other Antibiotics	Parasite Antibiotic Bacterial
Doramectin is a derivative of Ivermectin (HY-15310). Doramectin is a potent antiparasitic antibiotic. Doramectin is an active compound against S.mansoni in an NMRI mouse infection model .

HY-N2195

Nootkatone 2 Publications Verification (+)-Nootkatone	Structural Classification Terpenoids Sesquiterpenes Source classification Vitis vinifera cv. Zalema Plants Vitaceae	Others
Nootkatone, a neuroprotective agent from Vitis vinifera, has antioxidant and anti-inflammatory effects . Nootkatone improves cognitive impairment in lipopolysaccharide-induced mouse model of Alzheimer's disease .

HY-N4022

Hyuganin D Isobocconin; Seravschanin	Structural Classification Chrysanthemum × morifolium (Ramat.) Hemsl. Source classification Coumarins Phenylpropanoids Plants Umbelliferae	Others
Hyuganin D (Isobocconin) is a Coumarin (HY-N0709) constituent that substantially inhibits LPS (HY-D1056)-induced NO production in mouse peritoneal macrophages .

HY-N0370R

Bergapten (Standard)	Structural Classification other families Source classification Coumarins Phenylpropanoids Plants	Cytochrome P450 Autophagy
Bergapten (Standard) is the analytical standard of Bergapten. This product is intended for research and analytical applications. Bergapten is a natural anti-inflammatory and anti-tumor agent. Bergapten is inhibitory towards mouse and human CYP isoforms.

HY-14617

Paradol 3 Publications Verification [6]-Gingerone; [6]-Paradol	Zingiber officinale Roscoe Structural Classification Monophenols Classification of Application Fields Source classification Phenols Plants Disease Research Fields Cancer Zingiberaceae	COX
Paradol is a pungent phenolic substance found in ginger and other Zingiberaceae plants. Paradol is an effective inhibitor of tumor promotion in mouse skin carcinogenesis, binds to cyclooxygenase (COX)-2 active site.

HY-B1461

Deoxyarbutin	Structural Classification Natural Products Monophenols other families Classification of Application Fields Source classification Other Diseases Phenols Plants Disease Research Fields	Tyrosinase Apoptosis
Deoxyarbutin is an orally active tyrosinase inhibitor that can promote apoptosis of melanoma cells, enhance the vitality of mouse acinar cells, and has skin whitening and anti-tumor activity ^[1][2][3].

HY-N7563

α-Toxicarol	Structural Classification Flavonoids Leguminosae Source classification Derris trifoliata Lour. Plants Other Flavonoids	EBV
α-Toxicarol is a potent inhibitor of EBV.α-Toxicarol significantly inhibits mouse skin tumor in vivo. α-Toxicarol inhibits the TPA-induced EBV-EA activation .

HY-122467

Kumbicin C	Infection Alkaloids Microorganisms Classification of Application Fields Source classification Disease Research Fields Indole Alkaloids	Bacterial
Kumbicin C is a bis-indolyl benzenoid compound from an Australian soil fungus, Aspergillus kumbius. Kumbicin C inhibits the growth of mouse myeloma cells and the Gram-positive bacterium Bacillus subtilis .

HY-14595

Biochanin A 5+ Cited Publications 4-Methylgenistein; Olmelin	Structural Classification Neurological Disease Classification of Application Fields Source classification Trifolium pratense Linn. Plants Flavonoids Leguminosae Sunscreen Phenols Polyphenols Cosmetic Research Disease Research Fields Isoflavones Cancer	FAAH Autophagy Endogenous Metabolite
Biochanin A is a naturally occurring fatty acid amide hydrolase (FAAH) inhibitor, which inhibits FAAH with IC₅₀s of 1.8, 1.4 and 2.4 μM for mouse, rat, and human FAAH, respectively.

HY-N3646

Cudratricusxanthone A	Structural Classification Flavonoids Source classification Maclura tricuspidata Carriere Plants Moraceae Other Flavonoids	Others
Cudratricusxanthone A is isolated from Cudrania tricuspidata, and has anti-inflammatory, hepatoprotective, and anti-proliferative activities. Cudratricusxanthone A inhibits osteoclast differentiation and function in RAW 264.7 cells and mouse bone marrow monocytes .

HY-118726

Luotonin F	Structural Classification Alkaloids Peganum nigellastrum Bunge Zygophyllaceae Source classification Quinoline Alkaloids Plants	Topoisomerase
Luotonin F is an alkaloid found in the aerial parts of the P. nigellastrum Bunge. Luotonin F shows cytotoxic activity against mouse leukemia P-388 cells by inhibiting human topoisomerase II .

HY-N2556

Tirucallol	Triterpenes Classification of Application Fields Euphorbia boetica Terpenoids Source classification Euphorbiaceae Plants Disease Research Fields Inflammation/Immunology	Others
Tirucallol, a tetracyclic triterpene, is isolated from Euphorbia lacteal latex. Tirucallol has topical anti-inflammatory effect. Tirucallol can suppress ear edema in the mouse model and inhibit nitrite production in lipopolysaccharide-stimulated macrophages .

HY-N3312

Matairesinol	Infection Structural Classification other families Classification of Application Fields Anti-aging Source classification Lignans Phenols Polyphenols Phenylpropanoids Plants Disease Research Fields	Endogenous Metabolite
Matairesinol confers anti-allergic effects in an allergic dermatitis mouse model. DfE-induced changes in IL-4 and IFN-γ mRNA expression in the ears of NC/Nga mice were reversed by matairesinol application .

HY-118427

Asterriquinol D dimethyl ether	Infection Alkaloids Microorganisms Classification of Application Fields Source classification Disease Research Fields Indole Alkaloids	Parasite Endogenous Metabolite
Asterriquinol D dimethyl ether is a fungal metabolite, which can inhibit mouse myeloma NS-1 cell lines with an IC₅₀ of 28 μg/mL. Asterriquinol D dimethyl ether also inhibits *Tritrichomonas foetus* .

HY-N12122

Dehydropipernonaline	Structural Classification Alkaloids Piperidine Alkaloids Source classification Piperaceae Plants Piper retrofractum Vahl	Fungal
Dehydropipernonaline (Compound 24) is an amide compound. Dehydropipernonaline shows considerable cytotoxicity to L5178Y mouse lymphoma cells (IC₅₀8.9μM). Dehydropipernonaline can be used for screening antifungal and cytotoxicity .

HY-N8730

7,8,3′,4′-Tetramethoxyflavone	Structural Classification Flavonoids Punica granatum L. Flavones Source classification Punicaceae Plants	Others
7,8,3 ',4 '-Tetramethoxyflavone is an extract isolated from natural pomegranate juice and seeds. 7,8,3 ',4' -Tetramethoxyflavone has a protective effect on the neurotoxicity of paraquat-induced Parkinson's disease mouse model .

HY-N0109

Salidroside 20+ Cited Publications Rhodioloside	Structural Classification Classification of Application Fields Rhodiola rosea Linn. Crassulaceae Phenols Plants Disease Research Fields Cancer	PINK1/Parkin mTOR Apoptosis Prolyl Endopeptidase (PREP)
Salidroside (Rhodioloside) is a prolyl endopeptidase inhibitor. Salidroside alleviates cachexia symptoms in mouse models of cancer cachexia via activating mTOR signalling. Salidroside protects dopaminergic neurons by enhancing PINK1/Parkin-mediated mitophagy.

HY-N7699A

D-Trimannuronic acid	Polysaccharides other families Source classification Plants Saccharides	TNF Receptor
D-Trimannuronic acid, an alginate oligomer is extracted from seaweed. D-Trimannuronic acid can induce TNF‐α secretion by mouse macrophage cell lines. D-Trimannuronic acid can be used for the research of pain and vascular dementia .

HY-129228

Lychnopholide	Lychnophora pseudovillosissima Semir & Leitão Structural Classification Terpenoids Sesquiterpenes Source classification Plants Compositae	Parasite
Lychnopholide is a sesquiterpene lactone derived from the Asteraceae, Lychnopholide exhibits anti-trypanosomal activity against Trypanosoma cruzi. lychnopholide encapsulated in nanocapsules reduces its toxicity to mammalian cells. Lychnopholide ameliorates Chagas disease in mouse models .

HY-N0648R

Monotropein (Standard)	Structural Classification Iridoids Terpenoids Pyrola calliantha H. Andr. Source classification Rubiaceae Pyrolaceae Plants Morinda officinalis How	Others
Monotropein (Standard) is the analytical standard of Monotropein. This product is intended for research and analytical applications. Monotropein is an iridoid glycoside isolated Morinda officinalis. Monotropein inhibits the expression of inflammatory mediators in dextran sulfate sodium (DSS)-induced colitis mouse model .

HY-W008452

H-Tyr(3-I)-OH	Structural Classification Monophenols Classification of Application Fields Ketones, Aldehydes, Acids Source classification Phenols Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
H-Tyr(3-I)-OH is a potent and effective tyrosine hydroxylase inhibitor. H-Tyr(3-I)-OH is an intermediate in the production of thyroid hormones and has a role as a human or mouse metabolite .

HY-N7491

Verticilide	Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Inflammation/Immunology Disease Research Fields	Calcium Channel
Verticilide is a ryanodine-binding inhibitor and inhibits ryanodine binding to ryanodine receptors in the cockroach at an IC₅₀ value of 4.2 ?μM (whereas inhibition against mouse ryanodine receptors was weak (IC₅₀=53.9?μM)) .

HY-126644

Halocyamine B	Structural Classification Natural Products Animals Marine natural products Source classification Other marine organisms	Bacterial Fungal
Halocyamine B exhibits antimicrobial activity against a variety of bacteria and yeasts. Halocyamine B exhibits cytotoxicity to cultured neural cells of rat fetal brain, mouse neuroblastoma N18 cells, and human hepatoma HepG2 cells .

HY-17563

2'-Deoxyguanosine 4 Publications Verification Deoxyguanosine; Guanine deoxyriboside	Structural Classification Natural Products Human Gut Microbiota Metabolites Immune System Disorder Microorganisms Classification of Application Fields Source classification Disease markers Endocrine diseases Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite
2’-Deoxyguanosine (Deoxyguanosine) is a purine nucleoside with a variety of biological activities. 2’-Deoxyguanosine can induce DNA division in mouse thymus cells. 2’-Deoxyguanosine is a potent cell division inhibitor in plant cells .

HY-18732A

L-NMMA acetate 5 Publications Verification Tilarginine acetate; Methylarginine acetate	Cardiovascular Disease Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Cancer	NO Synthase Endogenous Metabolite
L-NMMA acetate is a nitric oxide synthase inhibitor of all NOS isoforms including NOS1, NOS2, and NOS3. The K_i values for nNOS (rat), eNOS (human), and iNOS (mouse) are approximately 0.18, 0.4, and 6 µM, respectively.

HY-N11772

Mutanocyclin	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Fungal
Mutanocyclin is a potent antifungal agent. Mutanocyclin inhibits Candida albicans (C. albicans) filamentation. Mutanocyclin decreases the mRNA expression of HWP1, ECE1, FLO8, TEC1. Mutanocyclin inhibits yeast-form in ex vivo mouse .

HY-141465

3-Hydroxybutyryl-CoA	Human Gut Microbiota Metabolites Microorganisms Source classification Endogenous metabolite	Endogenous Metabolite
3-Hydroxybutyryl-CoA is a metabolite which can be found in mouse or E.coli, et al. 3-Hydroxybutyryl-CoA has a 3-hydroxybutanoyl as the S-acyl component, and is an intermediate in the fermentation of butyric acid, and in the metabolism of lysine and tryptophan .

HY-167671

BE-10988	Structural Classification Natural Products Microorganisms Source classification	Topoisomerase
BE-10988 is a DNA topoisomerase inhibitor. BE-10988 inhibits the growth of Doxorubicin (HY-15142A)-resistant and vincristine-resistant P388 mouse leukemia cell lines by increasing the formation of DNA topoisomerase complexes .

HY-A0143

Dihomo-γ-linolenic acid 3 Publications Verification DGLA; all-cis-8,11,14-Eicosatrienoic acid	Cardiovascular Disease Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease markers Endocrine diseases Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite
Dihomo-γ-linolenic acid (DGLA) is a 20-carbon ω-6 fatty acid, with anti-inflammatory and anti-proliferative activities. Dihomo-γ-linolenic acid attenuates atherosclerosis in the apolipoprotein E deficient mouse model system .

HY-N0223

Epibetulinic acid	Triterpenes Structural Classification other families Classification of Application Fields Terpenoids Source classification Plants Disease Research Fields Endocrinology	NO Synthase Prostaglandin Receptor
Epibetulinic acid exhibits potent inhibitory effects on NO and prostaglandin E2 (PGE2) production in mouse macrophages (RAW 264.7) stimulated with bacterial endotoxin with IC₅₀s of 0.7 and 0.6 μM, respectively. Anti-inflammatory activity .

HY-N0128

Sclareol 1 Publications Verification	Structural Classification Classification of Application Fields Terpenoids Labiatae Source classification Diterpenoids Artemisia mexicana Willd. Plants Erigeron breviscapus (Vant.) Hand.-Mazz. Disease Research Fields Cancer	Apoptosis
Sclareol is isolated from Salvia sclarea with anticarcinogenic activity. Sclareol shows strong cytotoxic activity against mouse leukemia?(P-388), human epidermal?carcinoma?(KB) cells and human?leukemia?cell lines. Sclareol induces cell apoptosis .

Cat. No.	Product Name	Chemical Structure

HY-P1032S2

*Angiotensin I-13C6,15N (human, mouse, rat) TFA*
Angiotensin I-13C6,15N (human, mouse, rat) TFA is ¹³C and ¹⁵N labeled Angiotensin I (human, mouse, rat) TFA. Angiotensin I-13C6,15N (human, mouse, rat) TFA is a precursor of angiotensin II and is cleaved into angiotensin II by angiotensin converting enzyme (ACE) .

HY-W134007S1

Hexadecanoate-13C16 potassium 3 Publications Verification
Hexadecanoate- ¹³C₁₆ (potassium) is the ¹³C-labeled Hexadecanoate sodium. Hexadecanoate potassium can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells[1][2].

HY-P1032S

Angiotensin I-13C19,15N3 (human, mouse, rat)

Angiotensin I- ¹³C₁₉, ¹⁵N₃ (human, mouse, rat) is the ¹³C and ¹⁵N labeled Angiotensin I (human, mouse, rat) (HY-P1032). Cellulose (Pectin glycosidase) is a natural high molecular weight polysaccharide found in many plants and organisms. It is widely used in manufacturing industries, such as in paper making, textiles, food and medicine, etc. As a renewable resource, Cellulose is biodegradable and sustainable, and can also be used to manufacture chemicals such as Cellulose Esters, Cellulose Acetate and Cellulose Nitrate. In addition, Cellulose is often used as a food additive to increase the stability and quality of food .

HY-B1899S

Taurodeoxycholic acid-d5

Taurodeoxycholic acid-d₅ is the deuterium labeled Taurodeoxycholic acid (HY-B1899) . Taurodeoxycholic acid, a bile acid, stabilizes the mitochondrial membrane, decreases free radical formation. Taurodeoxycholic acid inhibits apoptosis by blocking a calcium-mediated apoptotic pathway as well as caspase-12 activation. Taurodeoxycholic acid exhibits neuroprotective effect in 3-nitropropionic acid induced mouse model or genetic mouse model of Huntington's disease (HD) .

HY-N0370S

Bergapten-d3
Bergapten-d₃ is deuterium labeled Bergapten. Bergapten is a natural anti-inflammatory and anti-tumor agent. Bergapten is inhibitory towards mouse and human CYP isoforms.

HY-16582AS

Sonidegib-d4
Sonidegib-d4 is a isotope of Sonidegib. Sonidegib is a potent and selective Smo antagonist with IC₅₀ of 1.3 nM and 2.5 nM for mouse and human Smo in binding assay, respectively .

HY-109591S

Oleoyl coenzyme A-13C18 lithium
Oleoyl coenzyme A- ¹³C₁₈ (lithium) is the ¹³C labeled Oleoyl Coenzyme A lithium[1]. Oleoyl coenzyme A (Oleoyl-CoA) is a thioester of oleic acid and coenzyme A. Oleoyl coenzyme A has a role as an Escherichia coli metabolite and a mouse metabolite[2][3].

HY-17399S

Racecadotril-d5
Racecadotril-d₅ is the deuterium labeled Racecadotril. Racecadotril (Acetorphan) is a neutral endopeptidase (NEP) inhibitor. Racecadotril and its active metabolite Thiorphan inhibits purified NEP activity from mouse brain with Kis of 4500 and 6.1 nM, , respectively. Antidiarrheal agent[1].

HY-B0149S3

Tranexamic acid-13C2,15N
Tranexamic acid- ¹³C₂, ¹⁵N (Cyclocapron- ¹³C₂, ¹⁵N) is the ¹³C₂ and ¹⁵N labeled Tranexamic acid. Tranexamic acid is an antifibrinolytic agent that alleviates liver damage and fibrosis in mouse models of chronic bile duct injury .

HY-B0349S

Meclizine-d8
Meclizine-d₈ is a deuterium labeled Meclizine. Meclizine is a histamine H1 receptor antagonist and has the potential to treat nausea and motion sickness. Meclizine is an agonist ligand for mouse constitutive androstane receptor (CAR) and an inverse agonist for Human CAR[1][2][3].

HY-126242S

Tyk2-IN-7

Tyk2-IN-7 is a TYK2 JH2 inhibitor, binds to TYK2 JH2 domain with IC50 and Ki.app of 0.00053 μM and 0.00007 μM, respectively. Tyk2-IN-7 provides a highly selective alternative to conventional TYK2 orthosteric inhibitors, inhibits TYK2/JAK1/JAK2 kinase domain. Tyk2-IN-7 provides robust inhibition in a mouse IL-12-induced IFNγ pharmacodynamic model as well as efficacy in an IL-23 and IL-12-dependent mouse colitis model[1].

HY-13956S

Pioglitazone-d4
Pioglitazone-d₄ is a deuterium labeled Pioglitazone. Pioglitazone (U 72107) is a potent and selective PPARγ agonist with high affinity binding to the PPARγ ligand-binding domain with EC50 of 0.93 and 0.99 μM for human and mouse PPARγ, respectively[1].

HY-157029S

KRASG12D-IN-1
KRASG12D-IN-1 (compound 22) is a KRAS ^G12D Inhibitor. KRASG12D-IN-1 has dose-dependent anti-tumor efficacy in the AsPC-1 xenograft mouse models with a tumor growth inhibition .

HY-157031S

KRASG12D-IN-2
KRASG12D-IN-2 (compound 28) is a KRAS ^G12D Inhibitor. KRASG12D-IN-1 has dose-dependent anti-tumor efficacy in the AsPC-1 xenograft mouse models with a tumor growth inhibition .

HY-13757AS1

Tamoxifen-d3

Tamoxifen-d₃ is the deuterium labeled Tamoxifen[1]. Tamoxifen (ICI 47699) is an orally active, selective estrogen receptor modulator (SERM) which blocks estrogen action in breast cells and can activate estrogen activity in other cells, such as bone, liver, and uterine cells[2][3][4]. Tamoxifen is a potent Hsp90 activator and enhances the Hsp90 molecular chaperone ATPase activity. Tamoxifen also potent inhibits infectious EBOV Zaire and Marburg (MARV) with IC50 of 0.1 μM and 1.8 μM, respectively[6]. Tamoxifen activates autophagy and induces apoptosis[5]. Tamoxifen also can induce gene knockout of CreER(T2) transgenic mouse[7].

HY-114360AS1

Taurohyodeoxycholic acid-d4 sodium
Taurohyodeoxycholic acid-d4 (sodium) is a deuterated labeled Taurohyodeoxycholic acid (sodium) . Taurohyodeoxycholic acid (THDCA) sodium is the taurine-conjugated form of the secondary bile acid hyodeoxycholic acid. Taurohyodeoxycholic acid can also reduce the activity and expression of myeloperoxidase TNF-α and IL-6, as well as colonic damage in TNBS-induced ulcerative colitis mouse model.

HY-17447SA

Tranylcypromine-d5 hydrochloride

Tranylcypromine-d₅ (hydrochloride) is a deuterium labeled (rel)-Tranylcypromine hydrochloride. Tranylcypromine hydrochloride is an irreversible, nonselective monoamine oxidase (MAO) inhibitor used in the treatment of depression. Tranylcypromine hydrochloride is also a lysine-specific demethylase 1 (LSD1) inhibitor, suppresses lesion growth and improves generalized hyperalgesia in mouse with induced endometriosis[1][2].

HY-N0830S18

Palmitic acid-d1
Palmitic acid-d is the deuterium labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. PA can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells[1][2].

HY-N0830S5

Palmitic acid-d3
Palmitic acid-d₃ is the deuterium labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. PA can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells[1][2].

HY-N0830S2

Palmitic acid-d31
Palmitic acid-d₃₁ is the deuterium labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. PA can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells[1][2].

HY-N0830BS

Palmitic acid-13C sodium
Palmitic acid- ¹³C (sodium) is the ¹³C-labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. Palmitic acid can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells[1][2].

HY-N0830S4

Palmitic acid-d2
Palmitic acid-d₂ is the deuterium labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. Palmitic acid can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells[1][2].

HY-N0830S7

Palmitic acid-d4
Palmitic acid-d₄ is the deuterium labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. Palmitic acid can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells[1][2].

HY-N0830S9

Palmitic acid-13C
Palmitic acid- ¹³C is the ¹³C-labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. Palmitic acid can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells[1][2].

HY-N0830S14

Palmitic acid-d17
Palmitic acid-d₁₇ is the deuterium labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. PA can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells[1][2].

HY-N0830S20

Palmitic acid-d9
Palmitic acid-d₉ is the deuterium labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. PA can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells[1][2].

HY-N0830S21

Palmitic acid-d5
Palmitic acid-d₅ is the deuterium labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. PA can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells[1][2].

HY-13762S

Tesmilifene-d4
Tesmilifene-d4 is the deuterium labeled Tesmilifene (HY-13762). Tesmilifene is an antihistamine agent and a chemical sensitizer. Tesmilifene targets cytochrome P450, exhibits hormonal effects on DNA synthesis in MCF-7 cells, and stimulates the tumor growth in mouse/rat models. Tesmilifene overcomes multidrug resistance .

HY-N0830S6

Palmitic acid-13C16 3 Publications Verification
Palmitic acid- ¹³C₁₆ is the ¹³C-labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. PA can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells[1][2].

HY-N0830BS1

Palmitic acid-13C16 sodium 3 Publications Verification
Palmitic acid- ¹³C₁₆ (sodium) is the ¹³C-labeled Palmitic acid sodium. Palmitic acid sodium is a long-chain saturated fatty acid commonly found in both animals and plants. Palmitic acid sodium can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells[1][2].

HY-N0830S10

Palmitic acid-13C2
Palmitic acid- ¹³C₂ is the ¹³C-labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. Palmitic acid can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells[1][2].

HY-N0830S11

Palmitic acid-d2-1
Palmitic acid-d₂-1 is the deuterium labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. Palmitic acid can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells[1][2].

HY-N0830S12

Palmitic acid-d4-1
Palmitic acid-d₄-1 is the deuterium labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. PA can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells[1][2][3].

HY-N0830S13

Palmitic acid-d4-2
Palmitic acid-d₄-2 is the deuterium labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. PA can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells[1][2].

HY-N0830S15

Palmitic acid-d2-2
Palmitic acid-d₂-2 is the deuterium labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. PA can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells[1][2].

HY-N0830S16

Palmitic acid-d2-3
Palmitic acid-d₂-3 is the deuterium labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. PA can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells[1][2].

HY-N0830S17

Palmitic acid-d2-4
Palmitic acid-d₂-4 is the deuterium labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. PA can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells[1][2].

HY-N0830S19

Palmitic acid-d2-5
Palmitic acid-d₂-5 is the deuterium labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. PA can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells[1][2].

HY-13956S1

Pioglitazone-d4 (alkyl)
Pioglitazone-d₄ (alkyl) (U 72107-d4 (alkyl)) is the deuterium labeled Pioglitazone. Pioglitazone (U 72107) is a potent and selective PPARγ agonist with high affinity binding to the PPARγ ligand-binding domain with EC50 of 0.93 and 0.99 μM for human and mouse PPARγ, respectively[1][2].

HY-N0830S3

Palmitic acid-1-13C
Palmitic acid-1- ¹³C is the ¹³C-labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. Palmitic acid can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells[1][2].

HY-N0830S8

Palmitic acid-9,10-d2
Palmitic acid-9,10-d₂ is the deuterium labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. Palmitic acid can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells[1][2].

HY-B0702S

Nicergoline-13C,d3
Nicergoline- ¹³C,d₃ is the ¹³C- and deuterium labeled Nicergoline. Nicergoline, an ergoline derivative ester of bromonicotinic acid, is a potent, selective and orally active antagonist of α1A-adrenoceptor. Nicergoline has vasodilator effects. Nicergoline also has ameliorative effects on cognitive function in mouse models of Alzheimer's disease[1][2].

HY-B0131S2

Prostaglandin E1-d9
Prostaglandin E1-d₉ is deuterium labeled Prostaglandin E1.Prostaglandin E1 is a prostanoid receptor ligand, with Kis of 1.1 nM, 2.1 nM, 10 nM, 33 nM and 36 nM for mouse EP3, EP4, EP2, IP and EP1, respectively. Prostaglandin E1 induces vasodilation and inh

HY-B1198S

Piperonyl butoxide-d9
Piperonyl butoxide-d₉ is the deuterium labeled Piperonyl butoxide.Piperonyl butoxide (ENT-14250) is a pesticide synergist and food additive. Piperonyl butoxide has adverse effects on reproduction, development and behavior in mice. Piperonyl butoxide can activate c-Jun and ATF-2 in mouse hepatocytes. Piperonyl butoxide is a liver cancer carcinogen in rats and mice .

HY-N0830S1

Palmitic acid-15,15,16,16,16-d5
Palmitic acid-15,15,16,16,16-d₅ is the deuterium labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. PA can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells[1][2].

HY-N0830S

Palmitic acid-1,2,3,4-13C4
Palmitic acid-1,2,3,4- ¹³C₄ is the ¹³C-labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. Palmitic acid can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells[1][2].

HY-W757743

Acalabrutinib-d3
Acalabrutinib-d₃ (ACP-196-d₃) is the deuterated form of Acalabrutinib (HY-17600). Acalabrutinib (ACP-196) is an orally active, irreversible, highly selective second-generation BTK inhibitor. Acalabrutinib covalently binds to Cys481 in the ATP-binding pocket of BTK. Acalabrutinib shows strong targeting and efficacy in mouse models of chronic lymphocytic leukemia (CLL).

HY-W008452S

H-Tyr(3-I)-OH-13C6
H-Tyr(3-I)-OH- ¹³C₆ is the ¹³C-labeled H-Tyr(3-I)-OH. H-Tyr(3-I)-OH is a potent and effective tyrosine hydroxylase inhibitor. H-Tyr(3-I)-OH is an intermediate in the production of thyroid hormones and has a role as a human or mouse metabolite[1][2].

HY-128423AS

Tylvalosin-d9
Tylvalosin-d₉ (Acetylisovaleryltylo?sin-d₉) is the deuterium labeled Tylvalosin (HY-128423A) . Tylvalosin is a third-generation macrolide, with anti-inflammatory property. Tylvalosin decreases the levels of IL-8, IL-6, IL-1β, PGE2, TNF-α and NO, and reduces the inflammatory cells recruitment and activation in mouse acute lung injury model .

HY-14894S2

Pragliflozin-13C6
Pragliflozin- ¹³C₆ (ASP1941- ¹³C₆) is ¹³C labeled Ipragliflozin. Ipragliflozin (ASP1941) is an orally active and selective SGLT2 inhibitor with IC₅₀s of 7.38 and 1876 nM, 6.73 and 1166 nM, 5.64 and 1380 nM for human SGLT2 and SGLT1, rat SGLT2 and SGLT1, mouse SGLT2 and SGLT1, respectively. Antidiabetic agent .

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks